# geneInfo

ensembl_gene_id: A0A1U7Q2K0
symbol: ND4L
gene_biotype: protein_coding
description:
  NADH-ubiquinone oxidoreductase chain 4L; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.


ensembl_gene_id: A0A1U7Q5H6
symbol: CYTB
gene_biotype: protein_coding
description:
  Cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.


ensembl_gene_id: A0A1U7QZJ7
symbol: NADSYN1
gene_biotype: protein_coding
description:
  Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family.


ensembl_gene_id: A0A1U7R0P3
symbol: GPN3
gene_biotype: protein_coding
description:
  GPN-loop GTPase 3; Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family.


ensembl_gene_id: A0A1U7R1P5
symbol: LOC102379317
gene_biotype: protein_coding
description:
  Cytochrome b-c1 complex subunit 6; This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1. Belongs to the UQCRH/QCR6 family.


ensembl_gene_id: A0A1U7R294
symbol: MED13
gene_biotype: protein_coding
description:
  Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.


ensembl_gene_id: A0A1U7R2D1
symbol: PAFAH1B1
gene_biotype: protein_coding
description:
  Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family.


ensembl_gene_id: A0A1U7R2G6
symbol: RBP7
gene_biotype: protein_coding
description:
  Retinoid-binding protein 7; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.


ensembl_gene_id: A0A1U7R2S3
symbol: DUPD1
gene_biotype: protein_coding
description:
  Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.


ensembl_gene_id: A0A1U7R2Y0
symbol: CHRM3
gene_biotype: protein_coding
description:
  Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.


ensembl_gene_id: A0A1U7R380
symbol: PANX2
gene_biotype: protein_coding
description:
  Pannexin; Structural component of the gap junctions and the hemichannels; Belongs to the pannexin family.


ensembl_gene_id: A0A1U7R3E5
symbol: POP4
gene_biotype: protein_coding
description:
  Ribonuclease P protein subunit p29; Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends.


ensembl_gene_id: A0A1U7R3H0
symbol: B3GAT2
gene_biotype: protein_coding
description:
  Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family.


ensembl_gene_id: A0A1U7R4G1
symbol: GABRA5
gene_biotype: protein_coding
description:
  Gamma-aminobutyric acid receptor subunit alpha-5; Belongs to the ligand-gated ion channel (TC 1.A.9) family.


ensembl_gene_id: A0A1U7R4M4
symbol: MFN1
gene_biotype: protein_coding
description:
  Mitofusin-1 isoform X1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.


ensembl_gene_id: A0A1U7R4T4
symbol: ATP4B
gene_biotype: protein_coding
description:
  Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.


ensembl_gene_id: A0A1U7R4U6
symbol: LOC102379010
gene_biotype: protein_coding
description:
  Molybdopterin synthase catalytic subunit; Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group; Belongs to the MoaE family. MOCS2B subfamily.


ensembl_gene_id: A0A1U7R5M7
symbol: HSD17B1
gene_biotype: protein_coding
description:
  Estradiol 17-beta-dehydrogenase 1 isoform X1; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: A0A1U7R663
symbol: SCN4A
gene_biotype: protein_coding
description:
  Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.


ensembl_gene_id: A0A1U7R6F1
symbol: PPP2R5C
gene_biotype: protein_coding
description:
  Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit.


ensembl_gene_id: A0A1U7R7A2
symbol: FANCC
gene_biotype: protein_coding
description:
  Fanconi anemia group C protein homolog; DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1.


ensembl_gene_id: A0A1U7R7D4
symbol: RET
gene_biotype: protein_coding
description:
  Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands.


ensembl_gene_id: A0A1U7R7G2
symbol: PLCB2
gene_biotype: protein_coding
description:
  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.


ensembl_gene_id: A0A1U7R7G8
symbol: RPUSD2
gene_biotype: protein_coding
description:
  Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.


ensembl_gene_id: A0A1U7R7N2
symbol: LOC102384332
gene_biotype: protein_coding
description:
  High-affinity choline transporter 1-like; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: A0A1U7R7T5
symbol: EIF4E3
gene_biotype: protein_coding
description:
  Eukaryotic translation initiation factor 4E type 3; Belongs to the eukaryotic initiation factor 4E family.


ensembl_gene_id: A0A1U7R840
symbol: CACNG8
gene_biotype: protein_coding
description:
  Voltage-dependent calcium channel gamma-8 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.


ensembl_gene_id: A0A1U7R875
symbol: MYO1H
gene_biotype: protein_coding
description:
  Unconventional myosin-Ih isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.


ensembl_gene_id: A0A1U7R893
symbol: SEC61B
gene_biotype: protein_coding
description:
  Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.


ensembl_gene_id: A0A1U7R8C1
symbol: P2RX7
gene_biotype: protein_coding
description:
  P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family.


ensembl_gene_id: A0A1U7R8I7
symbol: TRPA1
gene_biotype: protein_coding
description:
  Transient receptor potential cation channel subfamily A member 1; Belongs to the transient receptor (TC 1.A.4) family.


ensembl_gene_id: A0A1U7R8Q2
symbol: TALDO1
gene_biotype: protein_coding
description:
  Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.


ensembl_gene_id: A0A1U7R8R7
symbol: FUT10
gene_biotype: protein_coding
description:
  Alpha-(1,3)-fucosyltransferase; Probable fucosyltransferase; Belongs to the glycosyltransferase 10 family.


ensembl_gene_id: A0A1U7R8T3
symbol: GRIN3A
gene_biotype: protein_coding
description:
  Glutamate receptor ionotropic, NMDA 3A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.


ensembl_gene_id: A0A1U7R903
symbol: BBS7
gene_biotype: protein_coding
description:
  Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.


ensembl_gene_id: A0A1U7R918
symbol: OTC
gene_biotype: protein_coding
description:
  Ornithine carbamoyltransferase, mitochondrial; Belongs to the aspartate/ornithine carbamoyltransferase superfamily.


ensembl_gene_id: A0A1U7R935
symbol: LOC102374632
gene_biotype: protein_coding
description:
  Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.


ensembl_gene_id: A0A1U7R980
symbol: SLC5A9
gene_biotype: protein_coding
description:
  Sodium/glucose cotransporter 4 isoform X1; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: A0A1U7R9G5
symbol: LOC102369974
gene_biotype: protein_coding
description:
  S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.


ensembl_gene_id: A0A1U7R9S0
symbol: RPS6KB1
gene_biotype: protein_coding
description:
  Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.


ensembl_gene_id: A0A1U7R9T6
symbol: DUSP14
gene_biotype: protein_coding
description:
  Dual specificity protein phosphatase 14; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.


ensembl_gene_id: A0A1U7RA16
symbol: NDUFA10
gene_biotype: protein_coding
description:
  NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.


ensembl_gene_id: A0A1U7RA39
symbol: RER1
gene_biotype: protein_coding
description:
  Protein RER1; Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.


ensembl_gene_id: A0A1U7RAB7
symbol: MAP2K1
gene_biotype: protein_coding
description:
  Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily.


ensembl_gene_id: A0A1U7RAH9
symbol: LOC102385731
gene_biotype: protein_coding
description:
  Desmocollin-1 isoform X1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.


ensembl_gene_id: A0A1U7RAJ7
symbol: KIFC3
gene_biotype: protein_coding
description:
  Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.


ensembl_gene_id: A0A1U7RAU8
symbol: UPP2
gene_biotype: protein_coding
description:
  Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.


ensembl_gene_id: A0A1U7RAY3
symbol: NAT10
gene_biotype: protein_coding
description:
  RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.


ensembl_gene_id: A0A1U7RB21
symbol: FSHR
gene_biotype: protein_coding
description:
  Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways.


ensembl_gene_id: A0A1U7RBC3
symbol: LOC102383489
gene_biotype: protein_coding
description:
  Histone H3-like; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.


ensembl_gene_id: A0A1U7RBD7
symbol: NOSIP
gene_biotype: protein_coding
description:
  Nitric oxide synthase-interacting protein; Negatively regulates nitric oxide production by inducing nitric oxide synthase translocation to actin cytoskeleton and inhibiting its enzymatic activity; Belongs to the NOSIP family.


ensembl_gene_id: A0A1U7RBE6
symbol: CPT1C
gene_biotype: protein_coding
description:
  Carnitine O-palmitoyltransferase 1, brain isoform isoform X1; Belongs to the carnitine/choline acetyltransferase family.


ensembl_gene_id: A0A1U7RBP0
symbol: SLC25A12
gene_biotype: protein_coding
description:
  Calcium-binding mitochondrial carrier protein Aralar1 isoform X1; Belongs to the mitochondrial carrier (TC 2.A.29) family.


ensembl_gene_id: A0A1U7RBU3
symbol: GABRB3
gene_biotype: protein_coding
description:
  Gamma-aminobutyric acid receptor subunit beta-3 isoform X1; Belongs to the ligand-gated ion channel (TC 1.A.9) family.


ensembl_gene_id: A0A1U7RBV2
symbol: UNG
gene_biotype: protein_coding
description:
  Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.


ensembl_gene_id: A0A1U7RBW2
symbol: EIF4E2
gene_biotype: protein_coding
description:
  Eukaryotic translation initiation factor 4E type 2 isoform X1; Belongs to the eukaryotic initiation factor 4E family.


ensembl_gene_id: A0A1U7RBW3
symbol: ISCU
gene_biotype: protein_coding
description:
  Iron-sulfur cluster assembly enzyme ISCU, mitochondrial; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.


ensembl_gene_id: A0A1U7RC10
symbol: ATP2A2
gene_biotype: protein_coding
description:
  Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.


ensembl_gene_id: A0A1U7RC21
symbol: TPST2
gene_biotype: protein_coding
description:
  Protein-tyrosine sulfotransferase; Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate; Belongs to the protein sulfotransferase family.


ensembl_gene_id: A0A1U7RC69
symbol: MYO16
gene_biotype: protein_coding
description:
  Unconventional myosin-XVI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.


ensembl_gene_id: A0A1U7RCB7
symbol: MED7
gene_biotype: protein_coding
description:
  Mediator of RNA polymerase II transcription subunit 7; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery.


ensembl_gene_id: A0A1U7RCG7
symbol: LOC102373195
gene_biotype: protein_coding
description:
  Occludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Belongs to the ELL/occludin family.


ensembl_gene_id: A0A1U7RCI8
symbol: PMM2
gene_biotype: protein_coding
description:
  Phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions.


ensembl_gene_id: A0A1U7RCP8
symbol: CCDC78
gene_biotype: protein_coding
description:
  Coiled-coil domain-containing protein 78; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.


ensembl_gene_id: A0A1U7RCQ0
symbol: GTPBP3
gene_biotype: protein_coding
description:
  LOW QUALITY PROTEIN: tRNA modification GTPase GTPBP3, mitochondrial; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.


ensembl_gene_id: A0A1U7RCS8
symbol: CUNH19orf70
gene_biotype: protein_coding
description:
  MICOS complex subunit MIC13; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.


ensembl_gene_id: A0A1U7RCT8
symbol: MAP2K2
gene_biotype: protein_coding
description:
  Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily.


ensembl_gene_id: A0A1U7RCW3
symbol: RARS
gene_biotype: protein_coding
description:
  arginine--tRNA ligase, cytoplasmic isoform X1; Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: A0A1U7RD30
symbol: TMCO1
gene_biotype: protein_coding
description:
  Calcium load-activated calcium channel; Calcium-selective channel required to prevent calcium stores from overfilling.


ensembl_gene_id: A0A1U7RD57
symbol: RUVBL1
gene_biotype: protein_coding
description:
  RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.


ensembl_gene_id: A0A1U7RD60
symbol: PIF1
gene_biotype: protein_coding
description:
  ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.


ensembl_gene_id: A0A1U7RD90
symbol: LOC102371628
gene_biotype: protein_coding
description:
  Acid-sensing ion channel 2-like isoform X1; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.


ensembl_gene_id: A0A1U7RDI9
symbol: LOC102383500
gene_biotype: protein_coding
description:
  Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.


ensembl_gene_id: A0A1U7RDL0
symbol: PIGW
gene_biotype: protein_coding
description:
  Phosphatidylinositol-glycan biosynthesis class W protein; Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor.


ensembl_gene_id: A0A1U7RDL7
symbol: GUF1
gene_biotype: protein_coding
description:
  Translation factor GUF1, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.


ensembl_gene_id: A0A1U7RDU1
symbol: SLC9A8
gene_biotype: protein_coding
description:
  Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.


ensembl_gene_id: A0A1U7RDY8
symbol: LOC102368329
gene_biotype: protein_coding
description:
  Receptor-type guanylate cyclase gcy-22-like isoform X1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.


ensembl_gene_id: A0A1U7RE20
symbol: ATP5PD
gene_biotype: protein_coding
description:
  ATP synthase subunit d, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the cent [...]


ensembl_gene_id: A0A1U7RE31
symbol: WNT11
gene_biotype: protein_coding
description:
  Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.


ensembl_gene_id: A0A1U7RE50
symbol: ST3GAL1
gene_biotype: protein_coding
description:
  CMP-N-acetylneuraminate-beta-galactosamide- alpha-2,3-sialyltransferase 1 isoform X1; Belongs to the glycosyltransferase 29 family.


ensembl_gene_id: A0A1U7RE80
symbol: SEPT9
gene_biotype: protein_coding
description:
  Septin-9 isoform X1; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.


ensembl_gene_id: A0A1U7RE83
symbol: MTR
gene_biotype: protein_coding
description:
  Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.


ensembl_gene_id: A0A1U7REA2
symbol: KMO
gene_biotype: protein_coding
description:
  Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.


ensembl_gene_id: A0A1U7REA5
symbol: TTR
gene_biotype: protein_coding
description:
  Transthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.


ensembl_gene_id: A0A1U7REL1
symbol: EXOC2
gene_biotype: protein_coding
description:
  Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family.


ensembl_gene_id: A0A1U7REM4
symbol: SHH
gene_biotype: protein_coding
description:
  Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.


ensembl_gene_id: A0A1U7REQ3
symbol: GLO1
gene_biotype: protein_coding
description:
  Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.


ensembl_gene_id: A0A1U7RET4
symbol: LOC102377021
gene_biotype: protein_coding
description:
  NADH dehydrogenase [ubiquinone] 1 subunit C2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.


ensembl_gene_id: A0A1U7REU1
symbol: MRE11
gene_biotype: protein_coding
description:
  Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.


ensembl_gene_id: A0A1U7RFE9
symbol: ARPC5L
gene_biotype: protein_coding
description:
  Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.


ensembl_gene_id: A0A1U7RFJ5
symbol: GRPEL1
gene_biotype: protein_coding
description:
  GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family.


ensembl_gene_id: A0A1U7RFN2
symbol: RAN
gene_biotype: protein_coding
description:
  GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.


ensembl_gene_id: A0A1U7RFT1
symbol: GATB
gene_biotype: protein_coding
description:
  Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Belongs to the GatB/GatE family. GatB subfamily.


ensembl_gene_id: A0A1U7RFV9
symbol: LOC102378831
gene_biotype: protein_coding
description:
  Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.


ensembl_gene_id: A0A1U7RG22
symbol: PABPC4
gene_biotype: protein_coding
description:
  Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.


ensembl_gene_id: A0A1U7RG53
symbol: GPN2
gene_biotype: protein_coding
description:
  GPN-loop GTPase 2; Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family.


ensembl_gene_id: A0A1U7RGN3
symbol: TRMT5
gene_biotype: protein_coding
description:
  tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the TRM5 / TYW2 family.


ensembl_gene_id: A0A1U7RGS6
symbol: FABP2
gene_biotype: protein_coding
description:
  Fatty acid-binding protein, intestinal; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.


ensembl_gene_id: A0A1U7RGV9
symbol: ETFDH
gene_biotype: protein_coding
description:
  Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone.


ensembl_gene_id: A0A1U7RGY5
symbol: QRSL1
gene_biotype: protein_coding
description:
  Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Belongs to the amidase family. GatA subfamily.


ensembl_gene_id: A0A1U7RH01
symbol: SDHB
gene_biotype: protein_coding
description:
  Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).


ensembl_gene_id: A0A1U7RH12
symbol: COQ5
gene_biotype: protein_coding
description:
  2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2).


ensembl_gene_id: A0A1U7RH48
symbol: INSIG2
gene_biotype: protein_coding
description:
  Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family.


ensembl_gene_id: A0A1U7RH71
symbol: ADORA2A
gene_biotype: protein_coding
description:
  Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family.


ensembl_gene_id: A0A1U7RHG1
symbol: ELOF1
gene_biotype: protein_coding
description:
  Transcription elongation factor 1 homolog; Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions. Belongs to the ELOF1 family.


ensembl_gene_id: A0A1U7RHS1
symbol: KATNB1
gene_biotype: protein_coding
description:
  Katanin p80 WD40 repeat-containing subunit B1; Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.


ensembl_gene_id: A0A1U7RHU2
symbol: LSM8
gene_biotype: protein_coding
description:
  U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.


ensembl_gene_id: A0A1U7RHZ8
symbol: CAT
gene_biotype: protein_coding
description:
  Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.


ensembl_gene_id: A0A1U7RI46
symbol: ACMSD
gene_biotype: protein_coding
description:
  2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). Belongs to the metallo-dependent hydrolases superfamily.


ensembl_gene_id: A0A1U7RIA0
symbol: EEF1A1
gene_biotype: protein_coding
description:
  Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.


ensembl_gene_id: A0A1U7RIB2
symbol: CTPS1
gene_biotype: protein_coding
description:
  CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.


ensembl_gene_id: A0A1U7RIF8
symbol: RNF8
gene_biotype: protein_coding
description:
  E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...]


ensembl_gene_id: A0A1U7RIH2
symbol: ARPC1A
gene_biotype: protein_coding
description:
  Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.


ensembl_gene_id: A0A1U7RIH9
symbol: ATP6V0D2
gene_biotype: protein_coding
description:
  V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family.


ensembl_gene_id: A0A1U7RIJ2
symbol: GPR83
gene_biotype: protein_coding
description:
  Probable G-protein coupled receptor 83 isoform X1; Belongs to the G-protein coupled receptor 1 family.


ensembl_gene_id: A0A1U7RIK8
symbol: CACNG6
gene_biotype: protein_coding
description:
  Voltage-dependent calcium channel gamma-6 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.


ensembl_gene_id: A0A1U7RIL7
symbol: TSEN34
gene_biotype: protein_coding
description:
  tRNA-splicing endonuclease subunit Sen34; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structura [...]


ensembl_gene_id: A0A1U7RIT7
symbol: PRKCG
gene_biotype: protein_coding
description:
  Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.


ensembl_gene_id: A0A1U7RIV4
symbol: OLA1
gene_biotype: protein_coding
description:
  Obg-like ATPase 1; Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP.


ensembl_gene_id: A0A1U7RIW8
symbol: METAP1D
gene_biotype: protein_coding
description:
  Methionine aminopeptidase; Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met- Ala-, Cys, Gly, Pro, Ser, Thr, or Val).


ensembl_gene_id: A0A1U7RIZ8
symbol: LOC102388444
gene_biotype: protein_coding
description:
  Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.


ensembl_gene_id: A0A1U7RJ00
symbol: ACP6
gene_biotype: protein_coding
description:
  Lysophosphatidic acid phosphatase type 6 isoform X1; Belongs to the histidine acid phosphatase family.


ensembl_gene_id: A0A1U7RJ12
symbol: RIOX2
gene_biotype: protein_coding
description:
  Bifunctional lysine-specific demethylase and histidyl-hydroxylase; Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase.


ensembl_gene_id: A0A1U7RJ42
symbol: POLR3B
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: A0A1U7RJ94
symbol: PDGFRA
gene_biotype: protein_coding
description:
  Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development.


ensembl_gene_id: A0A1U7RJA0
symbol: ATP10D
gene_biotype: protein_coding
description:
  Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.


ensembl_gene_id: A0A1U7RJD0
symbol: LOC102371719
gene_biotype: protein_coding
description:
  Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.


ensembl_gene_id: A0A1U7RJF3
symbol: ST8SIA3
gene_biotype: protein_coding
description:
  sia-alpha-2,3-Gal-beta-1,4-GlcNAc-R:alpha 2,8-sialyltransferase; Belongs to the glycosyltransferase 29 family.


ensembl_gene_id: A0A1U7RJH6
symbol: SLC24A3
gene_biotype: protein_coding
description:
  Sodium/potassium/calcium exchanger 3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.


ensembl_gene_id: A0A1U7RJN6
symbol: PIGV
gene_biotype: protein_coding
description:
  GPI mannosyltransferase 2; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis.


ensembl_gene_id: A0A1U7RJP9
symbol: LOC102373987
gene_biotype: protein_coding
description:
  Gamma-aminobutyric acid receptor subunit rho-2 isoform X1; Belongs to the ligand-gated ion channel (TC 1.A.9) family.


ensembl_gene_id: A0A1U7RJR3
symbol: TRIT1
gene_biotype: protein_coding
description:
  tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37; Belongs to the IPP transferase family.


ensembl_gene_id: A0A1U7RJS6
symbol: STN1
gene_biotype: protein_coding
description:
  CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication.


ensembl_gene_id: A0A1U7RJT3
symbol: TRPC3
gene_biotype: protein_coding
description:
  Short transient receptor potential channel 3 isoform X1; Belongs to the transient receptor (TC 1.A.4) family.


ensembl_gene_id: A0A1U7RJV2
symbol: USP9X
gene_biotype: protein_coding
description:
  Probable ubiquitin carboxyl-terminal hydrolase FAF-X isoform X1; Belongs to the peptidase C19 family.


ensembl_gene_id: A0A1U7RK10
symbol: GABRP
gene_biotype: protein_coding
description:
  Gamma-aminobutyric acid receptor subunit pi; Belongs to the ligand-gated ion channel (TC 1.A.9) family.


ensembl_gene_id: A0A1U7RK46
symbol: LOC102368517
gene_biotype: protein_coding
description:
  Glyoxylate reductase/hydroxypyruvate reductase-like isoform X1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: A0A1U7RK91
symbol: ATP6V0A4
gene_biotype: protein_coding
description:
  V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.


ensembl_gene_id: A0A1U7RK97
symbol: TOP3B
gene_biotype: protein_coding
description:
  DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.


ensembl_gene_id: A0A1U7RKP8
symbol: APIP
gene_biotype: protein_coding
description:
  Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway. May play a role in apoptosis.


ensembl_gene_id: A0A1U7RKS6
symbol: NLK
gene_biotype: protein_coding
description:
  Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.


ensembl_gene_id: A0A1U7RKT2
symbol: NSMCE4A
gene_biotype: protein_coding
description:
  Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.


ensembl_gene_id: A0A1U7RKT5
symbol: PRMT3
gene_biotype: protein_coding
description:
  Protein arginine N-methyltransferase 3 isoform X1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.


ensembl_gene_id: A0A1U7RKT9
symbol: GATC
gene_biotype: protein_coding
description:
  Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Belongs to the GatC family.


ensembl_gene_id: A0A1U7RKZ0
symbol: DRAXIN
gene_biotype: protein_coding
description:
  Draxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord; Belongs to the draxin family.


ensembl_gene_id: A0A1U7RKZ5
symbol: MFN2
gene_biotype: protein_coding
description:
  Mitofusin-2 isoform X1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.


ensembl_gene_id: A0A1U7RL26
symbol: GJA10
gene_biotype: protein_coding
description:
  Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.


ensembl_gene_id: A0A1U7RLA8
symbol: TIPIN
gene_biotype: protein_coding
description:
  TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family.


ensembl_gene_id: A0A1U7RLA9
symbol: CACNG7
gene_biotype: protein_coding
description:
  Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.


ensembl_gene_id: A0A1U7RLG1
symbol: NUDT21
gene_biotype: protein_coding
description:
  Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The  [...]


ensembl_gene_id: A0A1U7RLK3
symbol: USB1
gene_biotype: protein_coding
description:
  U6 snRNA phosphodiesterase; Phosphodiesterase responsible for the U6 snRNA 3' end processing. Acts as an exoribonuclease (RNase) responsible for trimming the poly(U) tract of the last nucleotides in the pre-U6 snRNA molecule, leading to the formation of mature U6 snRNA; Belongs to the 2H phosphoesterase superfamily. USB1 family.


ensembl_gene_id: A0A1U7RLK5
symbol: EIF2B1
gene_biotype: protein_coding
description:
  Translation initiation factor eIF-2B subunit alpha; Belongs to the eIF-2B alpha/beta/delta subunits family.


ensembl_gene_id: A0A1U7RLN9
symbol: LOC102381626
gene_biotype: protein_coding
description:
  Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]


ensembl_gene_id: A0A1U7RLT1
symbol: KIF27
gene_biotype: protein_coding
description:
  Kinesin-like protein KIF27; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.


ensembl_gene_id: A0A1U7RLT6
symbol: SLC28A3
gene_biotype: protein_coding
description:
  Sodium/nucleoside cotransporter; Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.


ensembl_gene_id: A0A1U7RLZ8
symbol: TFB1M
gene_biotype: protein_coding
description:
  rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.


ensembl_gene_id: A0A1U7RM08
symbol: CKS2
gene_biotype: protein_coding
description:
  Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.


ensembl_gene_id: A0A1U7RM51
symbol: PPAT
gene_biotype: protein_coding
description:
  Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.


ensembl_gene_id: A0A1U7RMD6
symbol: DUSP18
gene_biotype: protein_coding
description:
  Dual specificity protein phosphatase 18; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.


ensembl_gene_id: A0A1U7RME8
symbol: PGAP3
gene_biotype: protein_coding
description:
  Post-GPI attachment to proteins factor 3; Involved in the lipid remodeling steps of GPI-anchor maturation; Belongs to the PGAP3 family.


ensembl_gene_id: A0A1U7RMG6
symbol: LIN7C
gene_biotype: protein_coding
description:
  Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family.


ensembl_gene_id: A0A1U7RMQ5
symbol: MAT2B
gene_biotype: protein_coding
description:
  Methionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine.


ensembl_gene_id: A0A1U7RMQ8
symbol: LSM5
gene_biotype: protein_coding
description:
  U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.


ensembl_gene_id: A0A1U7RMT8
symbol: UBE3A
gene_biotype: protein_coding
description:
  Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates.


ensembl_gene_id: A0A1U7RMX0
symbol: POLR2H
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.


ensembl_gene_id: A0A1U7RMY3
symbol: ATP6V0B
gene_biotype: protein_coding
description:
  V-type proton ATPase 21 kDa proteolipid subunit; Belongs to the V-ATPase proteolipid subunit family.


ensembl_gene_id: A0A1U7RN45
symbol: NAXD
gene_biotype: protein_coding
description:
  ATP-dependent (S)-NAD(P)H-hydrate dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.


ensembl_gene_id: A0A1U7RN98
symbol: ATP6V1B2
gene_biotype: protein_coding
description:
  Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family.


ensembl_gene_id: A0A1U7RNA2
symbol: BMT2
gene_biotype: protein_coding
description:
  S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]


ensembl_gene_id: A0A1U7RNA6
symbol: NMT1
gene_biotype: protein_coding
description:
  Glycylpeptide N-tetradecanoyltransferase; Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins; Belongs to the NMT family.


ensembl_gene_id: A0A1U7RNB3
symbol: AP3M2
gene_biotype: protein_coding
description:
  LOW QUALITY PROTEIN: AP-3 complex subunit mu-2; Belongs to the adaptor complexes medium subunit family.


ensembl_gene_id: A0A1U7RNE7
symbol: PIK3CG
gene_biotype: protein_coding
description:
  Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform isoform X1; Belongs to the PI3/PI4-kinase family.


ensembl_gene_id: A0A1U7RNJ3
symbol: TMEM97
gene_biotype: protein_coding
description:
  Transmembrane protein 97; Intracellular orphan receptor that binds numerous drugs and which is highly expressed in various proliferating cells. Corresponds to the sigma-2 receptor, which is thought to play important role in regulating cell survival, morphology and differentiation. May play a role as a regulator of cellular cholesterol homeostasis. May function as sterol isomerase. May alter the activity of some cytochrome P450 proteins.


ensembl_gene_id: A0A1U7RNM9
symbol: TMEM269
gene_biotype: protein_coding
description:
  Transmembrane protein 269 isoform X1; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: A0A1U7RNP4
symbol: DDOST
gene_biotype: protein_coding
description:
  Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across t [...]


ensembl_gene_id: A0A1U7RNQ8
symbol: NDUFS7
gene_biotype: protein_coding
description:
  NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial; Belongs to the complex I 20 kDa subunit family.


ensembl_gene_id: A0A1U7RNR4
symbol: CNN2
gene_biotype: protein_coding
description:
  Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.


ensembl_gene_id: A0A1U7RNT7
symbol: ATP5MC1
gene_biotype: protein_coding
description:
  ATP synthase F(0) complex subunit C1, mitochondrial isoform X1; Belongs to the ATPase C chain family.


ensembl_gene_id: A0A1U7RNX6
symbol: WDR12
gene_biotype: protein_coding
description:
  Ribosome biogenesis protein WDR12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.


ensembl_gene_id: A0A1U7RNY6
symbol: TUBB4A
gene_biotype: protein_coding
description:
  Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.


ensembl_gene_id: A0A1U7RNZ0
symbol: TRNT1
gene_biotype: protein_coding
description:
  CCA tRNA nucleotidyltransferase 1, mitochondrial isoform X1; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.


ensembl_gene_id: A0A1U7RP15
symbol: KCNK1
gene_biotype: protein_coding
description:
  Potassium channel subfamily K member 1 isoform X1; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.


ensembl_gene_id: A0A1U7RP31
symbol: ASNA1
gene_biotype: protein_coding
description:
  ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion.  [...]


ensembl_gene_id: A0A1U7RPH5
symbol: ARPP19
gene_biotype: protein_coding
description:
  cAMP-regulated phosphoprotein 19; Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. Belongs to the endosulfine family.


ensembl_gene_id: A0A1U7RPI8
symbol: LOC102384045
gene_biotype: protein_coding
description:
  Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.


ensembl_gene_id: A0A1U7RPK0
symbol: GABRB1
gene_biotype: protein_coding
description:
  Gamma-aminobutyric acid receptor subunit beta-1 isoform X1; Belongs to the ligand-gated ion channel (TC 1.A.9) family.


ensembl_gene_id: A0A1U7RPK2
symbol: ACTR8
gene_biotype: protein_coding
description:
  Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily.


ensembl_gene_id: A0A1U7RPK5
symbol: LOC102379106
gene_biotype: protein_coding
description:
  Myelin P2 protein-like; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.


ensembl_gene_id: A0A1U7RPK9
symbol: RABGGTB
gene_biotype: protein_coding
description:
  Geranylgeranyl transferase type-2 subunit beta; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C- terminal sequence -XXCC, -XCXC and -CCXX.


ensembl_gene_id: A0A1U7RPM0
symbol: ST6GALNAC5
gene_biotype: protein_coding
description:
  alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5; Belongs to the glycosyltransferase 29 family.


ensembl_gene_id: A0A1U7RPV6
symbol: SCNN1B
gene_biotype: protein_coding
description:
  Amiloride-sensitive sodium channel subunit beta; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.


ensembl_gene_id: A0A1U7RPX7
symbol: SOD2
gene_biotype: protein_coding
description:
  Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.


ensembl_gene_id: A0A1U7RPZ3
symbol: MYO7A
gene_biotype: protein_coding
description:
  Unconventional myosin-VIIa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.


ensembl_gene_id: A0A1U7RPZ4
symbol: DOHH
gene_biotype: protein_coding
description:
  Deoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor; Belongs to the deoxyhypusine hydroxylase family.


ensembl_gene_id: A0A1U7RQ10
symbol: ATP6V1H
gene_biotype: protein_coding
description:
  V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system.


ensembl_gene_id: A0A1U7RQ33
symbol: SIRT5
gene_biotype: protein_coding
description:
  NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.


ensembl_gene_id: A0A1U7RQ42
symbol: PPARG
gene_biotype: protein_coding
description:
  Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]


ensembl_gene_id: A0A1U7RQ44
symbol: SEC16A
gene_biotype: protein_coding
description:
  Protein transport protein sec16; Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus.


ensembl_gene_id: A0A1U7RQ57
symbol: MED9
gene_biotype: protein_coding
description:
  Mediator of RNA polymerase II transcription subunit 9; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.


ensembl_gene_id: A0A1U7RQ63
symbol: NDUFA8
gene_biotype: protein_coding
description:
  NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.


ensembl_gene_id: A0A1U7RQA3
symbol: SLC2A8
gene_biotype: protein_coding
description:
  Solute carrier family 2, facilitated glucose transporter member 8; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.


ensembl_gene_id: A0A1U7RQB7
symbol: GLDC
gene_biotype: protein_coding
description:
  Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine.


ensembl_gene_id: A0A1U7RQB9
symbol: CDC123
gene_biotype: protein_coding
description:
  Cell division cycle protein 123 homolog; Required for S phase entry of the cell cycle. Belongs to the CDC123 family.


ensembl_gene_id: A0A1U7RQF9
symbol: TUBGCP5
gene_biotype: protein_coding
description:
  Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family.


ensembl_gene_id: A0A1U7RQL9
symbol: CAV3
gene_biotype: protein_coding
description:
  Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.


ensembl_gene_id: A0A1U7RQM3
symbol: TRH
gene_biotype: protein_coding
description:
  Pro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems.


ensembl_gene_id: A0A1U7RQQ1
symbol: LOC102381815
gene_biotype: protein_coding
description:
  Gamma-aminobutyric acid receptor subunit alpha-3-like; Belongs to the ligand-gated ion channel (TC 1.A.9) family.


ensembl_gene_id: A0A1U7RQV1
symbol: PELO
gene_biotype: protein_coding
description:
  Protein pelota homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs.


ensembl_gene_id: A0A1U7RQV4
symbol: MED17
gene_biotype: protein_coding
description:
  Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.


ensembl_gene_id: A0A1U7RQX5
symbol: URM1
gene_biotype: protein_coding
description:
  Ubiquitin-related modifier 1; Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically [...]


ensembl_gene_id: A0A1U7RQY6
symbol: SNU13
gene_biotype: protein_coding
description:
  Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family.


ensembl_gene_id: A0A1U7RQZ7
symbol: PDE6D
gene_biotype: protein_coding
description:
  Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta; Promotes the release of prenylated target proteins from cellular membranes. Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location. Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E. Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI). Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasing the nucleotide [...]


ensembl_gene_id: A0A1U7RR06
symbol: CACNG1
gene_biotype: protein_coding
description:
  Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics.


ensembl_gene_id: A0A1U7RR30
symbol: PRDM12
gene_biotype: protein_coding
description:
  PR domain zinc finger protein 12; Involved in the positive regulation of histone H3-K9 dimethylation; Belongs to the class V-like SAM-binding methyltransferase superfamily.


ensembl_gene_id: A0A1U7RR67
symbol: LOC102378459
gene_biotype: protein_coding
description:
  Mitochondrial ornithine transporter 1-like; Belongs to the mitochondrial carrier (TC 2.A.29) family.


ensembl_gene_id: A0A1U7RR68
symbol: SRP72
gene_biotype: protein_coding
description:
  Signal recognition particle subunit SRP72; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane; Belongs to the SRP72 family.


ensembl_gene_id: A0A1U7RR93
symbol: LOC102387947
gene_biotype: protein_coding
description:
  Potassium voltage-gated channel subfamily A member 1 isoform X1; Belongs to the potassium channel family.


ensembl_gene_id: A0A1U7RRC7
symbol: NDUFAF7
gene_biotype: protein_coding
description:
  Protein arginine methyltransferase NDUFAF7; Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).


ensembl_gene_id: A0A1U7RRI0
symbol: ENTPD8
gene_biotype: protein_coding
description:
  Ectonucleoside triphosphate diphosphohydrolase 8 isoform X1; Belongs to the GDA1/CD39 NTPase family.


ensembl_gene_id: A0A1U7RRI4
symbol: RARS2
gene_biotype: protein_coding
description:
  Probable arginine--tRNA ligase, mitochondrial isoform X1; Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: A0A1U7RRI9
symbol: RAD51
gene_biotype: protein_coding
description:
  DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]


ensembl_gene_id: A0A1U7RRK1
symbol: PYGB
gene_biotype: protein_coding
description:
  Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.


ensembl_gene_id: A0A1U7RRL9
symbol: GOSR2
gene_biotype: protein_coding
description:
  Golgi SNAP receptor complex member 2 isoform X1; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network.


ensembl_gene_id: A0A1U7RRM1
symbol: CALCRL
gene_biotype: protein_coding
description:
  Calcitonin gene-related peptide type 1 receptor; Belongs to the G-protein coupled receptor 2 family.


ensembl_gene_id: A0A1U7RRT4
symbol: COPG1
gene_biotype: protein_coding
description:
  Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.


ensembl_gene_id: A0A1U7RRT5
symbol: HAAO
gene_biotype: protein_coding
description:
  3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family.


ensembl_gene_id: A0A1U7RRV8
symbol: LSM3
gene_biotype: protein_coding
description:
  U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.


ensembl_gene_id: A0A1U7RRY8
symbol: SLC25A22
gene_biotype: protein_coding
description:
  Mitochondrial glutamate carrier 1 isoform X1; Belongs to the mitochondrial carrier (TC 2.A.29) family.


ensembl_gene_id: A0A1U7RS41
symbol: SLC25A27
gene_biotype: protein_coding
description:
  Mitochondrial uncoupling protein 4 isoform X1; Belongs to the mitochondrial carrier (TC 2.A.29) family.


ensembl_gene_id: A0A1U7RS77
symbol: MBOAT1
gene_biotype: protein_coding
description:
  Lysophospholipid acyltransferase 1 isoform X1; Belongs to the membrane-bound acyltransferase family.


ensembl_gene_id: A0A1U7RS96
symbol: MNAT1
gene_biotype: protein_coding
description:
  CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex.


ensembl_gene_id: A0A1U7RSB5
symbol: TRMT61A
gene_biotype: protein_coding
description:
  tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A; Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.


ensembl_gene_id: A0A1U7RSB8
symbol: MED10
gene_biotype: protein_coding
description:
  Mediator of RNA polymerase II transcription subunit 10; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.


ensembl_gene_id: A0A1U7RSD0
symbol: KIF4A
gene_biotype: protein_coding
description:
  Chromosome-associated kinesin KIF4A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.


ensembl_gene_id: A0A1U7RSL5
symbol: SLC2A1
gene_biotype: protein_coding
description:
  Solute carrier family 2, facilitated glucose transporter member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.


ensembl_gene_id: A0A1U7RSM0
symbol: SEPT6
gene_biotype: protein_coding
description:
  Septin-6 isoform X1; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.


ensembl_gene_id: A0A1U7RST2
symbol: GNGT2
gene_biotype: protein_coding
description:
  Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.


ensembl_gene_id: A0A1U7RSU7
symbol: MTCH1
gene_biotype: protein_coding
description:
  Mitochondrial carrier homolog 1 isoform X1; Belongs to the mitochondrial carrier (TC 2.A.29) family.


ensembl_gene_id: A0A1U7RSX2
symbol: SLC44A2
gene_biotype: protein_coding
description:
  LOW QUALITY PROTEIN: choline transporter-like protein 2; Belongs to the CTL (choline transporter-like) family.


ensembl_gene_id: A0A1U7RSY4
symbol: POLR1A
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: A0A1U7RT09
symbol: SMARCAL1
gene_biotype: protein_coding
description:
  SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily.


ensembl_gene_id: A0A1U7RT52
symbol: LOC102374986
gene_biotype: protein_coding
description:
  Histone-arginine methyltransferase CARM1-like isoform X1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.


ensembl_gene_id: A0A1U7RT64
symbol: ELOVL2
gene_biotype: protein_coding
description:
  Elongation of very long chain fatty acids protein 2; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA). May participate to the production  [...]


ensembl_gene_id: A0A1U7RT81
symbol: RPLP0
gene_biotype: protein_coding
description:
  60S acidic ribosomal protein P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10.


ensembl_gene_id: A0A1U7RT91
symbol: POP5
gene_biotype: protein_coding
description:
  Ribonuclease P/MRP protein subunit POP5; Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.


ensembl_gene_id: A0A1U7RTD0
symbol: SMARCB1
gene_biotype: protein_coding
description:
  SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family.


ensembl_gene_id: A0A1U7RTH3
symbol: SLC25A3
gene_biotype: protein_coding
description:
  Phosphate carrier protein, mitochondrial isoform X1; Belongs to the mitochondrial carrier (TC 2.A.29) family.


ensembl_gene_id: A0A1U7RTP0
symbol: RHAG
gene_biotype: protein_coding
description:
  Ammonium transporter Rh type A; Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.


ensembl_gene_id: A0A1U7RTP2
symbol: SLC10A7
gene_biotype: protein_coding
description:
  Sodium/bile acid cotransporter; Does not show transport activity towards bile acids or steroid sulfates; Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.


ensembl_gene_id: A0A1U7RTP5
symbol: NMD3
gene_biotype: protein_coding
description:
  60S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family.


ensembl_gene_id: A0A1U7RTP8
symbol: SLC24A5
gene_biotype: protein_coding
description:
  Sodium/potassium/calcium exchanger 5; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.


ensembl_gene_id: A0A1U7RTU2
symbol: CAPZA3
gene_biotype: protein_coding
description:
  F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.


ensembl_gene_id: A0A1U7RTW3
symbol: MSRB2
gene_biotype: protein_coding
description:
  Peptide-methionine (R)-S-oxide reductase; Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues.


ensembl_gene_id: A0A1U7RTX9
symbol: MPC2
gene_biotype: protein_coding
description:
  Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.


ensembl_gene_id: A0A1U7RUF7
symbol: VPS41
gene_biotype: protein_coding
description:
  Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family.


ensembl_gene_id: A0A1U7RUG7
symbol: CPT1A
gene_biotype: protein_coding
description:
  Carnitine O-palmitoyltransferase 1, liver isoform isoform X1; Belongs to the carnitine/choline acetyltransferase family.


ensembl_gene_id: A0A1U7RUI5
symbol: B4GALNT4
gene_biotype: protein_coding
description:
  Beta-1,4-N-acetylgalactosaminyltransferase; Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N'- diacetyllactosediamine, GalNAc-beta-1,4-GlcNAc structures in N-linked glycans and probably O-linked glycans.


ensembl_gene_id: A0A1U7RUL4
symbol: TRAPPC3L
gene_biotype: protein_coding
description:
  Trafficking protein particle complex subunit; May play a role in vesicular transport from endoplasmic reticulum to Golgi.


ensembl_gene_id: A0A1U7RUN4
symbol: ARL1
gene_biotype: protein_coding
description:
  ADP-ribosylation factor-like protein 1 isoform X2; Belongs to the small GTPase superfamily. Arf family.


ensembl_gene_id: A0A1U7RUW3
symbol: EIF3I
gene_biotype: protein_coding
description:
  Eukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.


ensembl_gene_id: A0A1U7RUY5
symbol: CRAT
gene_biotype: protein_coding
description:
  Carnitine O-acetyltransferase isoform X3; Belongs to the carnitine/choline acetyltransferase family.


ensembl_gene_id: A0A1U7RUY6
symbol: BDNF
gene_biotype: protein_coding
description:
  Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family.


ensembl_gene_id: A0A1U7RV46
symbol: ST6GALNAC4
gene_biotype: protein_coding
description:
  N-acetylgalactosaminide alpha-2,6-sialyltransferase (sialyltransferase 7D); Belongs to the glycosyltransferase 29 family.


ensembl_gene_id: A0A1U7RV67
symbol: HOXD9
gene_biotype: protein_coding
description:
  Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family.


ensembl_gene_id: A0A1U7RV76
symbol: LOC102369474
gene_biotype: protein_coding
description:
  Heparan-sulfate 6-O-sulfotransferase; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.


ensembl_gene_id: A0A1U7RVF1
symbol: SLC26A1
gene_biotype: protein_coding
description:
  Sulfate anion transporter 1; Mediates sulfate transport with high affinity. Mediates oxalate transport. Mediates bicarbonate transport. Does not accept succinate as cosubstrate; Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.


ensembl_gene_id: A0A1U7RVP3
symbol: CRYBG1
gene_biotype: protein_coding
description:
  Beta/gamma crystallin domain-containing protein 1 isoform X2; Belongs to the beta/gamma-crystallin family.


ensembl_gene_id: A0A1U7RVP4
symbol: LOC102373915
gene_biotype: protein_coding
description:
  Uricase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin. Belongs to the uricase family.


ensembl_gene_id: A0A1U7RVQ8
symbol: DUSP1
gene_biotype: protein_coding
description:
  Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.


ensembl_gene_id: A0A1U7RVW0
symbol: LOC102385096
gene_biotype: protein_coding
description:
  Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.


ensembl_gene_id: A0A1U7RWB0
symbol: NOP2
gene_biotype: protein_coding
description:
  Probable 28S rRNA (Cytosine(4447)-C(5))-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.


ensembl_gene_id: A0A1U7RWF0
symbol: PSEN1
gene_biotype: protein_coding
description:
  Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.


ensembl_gene_id: A0A1U7RWF5
symbol: LOC102383053
gene_biotype: protein_coding
description:
  Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.


ensembl_gene_id: A0A1U7RWG5
symbol: NDUFA12
gene_biotype: protein_coding
description:
  NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.


ensembl_gene_id: A0A1U7RWN1
symbol: LOC102369897
gene_biotype: protein_coding
description:
  Septin-2; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.


ensembl_gene_id: A0A1U7RWP8
symbol: SLC8A3
gene_biotype: protein_coding
description:
  Sodium/calcium exchanger 3 isoform X1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.


ensembl_gene_id: A0A1U7RWU6
symbol: TEAD3
gene_biotype: protein_coding
description:
  Transcriptional enhancer factor TEF-5; Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.


ensembl_gene_id: A0A1U7RWZ5
symbol: MYO6
gene_biotype: protein_coding
description:
  Unconventional myosin-VI isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.


ensembl_gene_id: A0A1U7RX39
symbol: ST6GALNAC3
gene_biotype: protein_coding
description:
  alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 isoform X1; Belongs to the glycosyltransferase 29 family.


ensembl_gene_id: A0A1U7RX54
symbol: ATP6V1C2
gene_biotype: protein_coding
description:
  V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.


ensembl_gene_id: A0A1U7RX74
symbol: KCNK18
gene_biotype: protein_coding
description:
  Potassium channel subfamily K member 18; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.


ensembl_gene_id: A0A1U7RX95
symbol: PLCG2
gene_biotype: protein_coding
description:
  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.


ensembl_gene_id: A0A1U7RXB7
symbol: KRR1
gene_biotype: protein_coding
description:
  KRR1 small subunit processome component; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.


ensembl_gene_id: A0A1U7RXD4
symbol: PAN3
gene_biotype: protein_coding
description:
  PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA deca [...]


ensembl_gene_id: A0A1U7RXI3
symbol: LOC102382075
gene_biotype: protein_coding
description:
  Gamma-aminobutyric acid receptor subunit beta-4 isoform X1; Belongs to the ligand-gated ion channel (TC 1.A.9) family.


ensembl_gene_id: A0A1U7RXT4
symbol: CCT7
gene_biotype: protein_coding
description:
  T-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.


ensembl_gene_id: A0A1U7RXW6
symbol: ECHDC2
gene_biotype: protein_coding
description:
  enoyl-CoA hydratase domain-containing protein 2, mitochondrial isoform X1; Belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: A0A1U7RXX9
symbol: ATP6V1G1
gene_biotype: protein_coding
description:
  V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.


ensembl_gene_id: A0A1U7RY61
symbol: ETNPPL
gene_biotype: protein_coding
description:
  Ethanolamine-phosphate phospho-lyase isoform X1; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: A0A1U7RY63
symbol: MVD
gene_biotype: protein_coding
description:
  Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes.


ensembl_gene_id: A0A1U7RY70
symbol: EIF3L
gene_biotype: protein_coding
description:
  Eukaryotic translation initiation factor 3 subunit L; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.


ensembl_gene_id: A0A1U7RY82
symbol: CTU2
gene_biotype: protein_coding
description:
  Cytoplasmic tRNA 2-thiolation protein 2; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with CTU1/ATPBD3 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.


ensembl_gene_id: A0A1U7RY91
symbol: LOC102382746
gene_biotype: protein_coding
description:
  Tricarboxylate transport protein, mitochondrial-like; Belongs to the mitochondrial carrier (TC 2.A.29) family.


ensembl_gene_id: A0A1U7RY95
symbol: EIF3D
gene_biotype: protein_coding
description:
  Eukaryotic translation initiation factor 3 subunit D; mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. In the eIF-3 complex, eif3d specifically recognizes and binds the 7- methylguanosine cap of a subset of mRNAs.


ensembl_gene_id: A0A1U7RYB9
symbol: CAMK2A
gene_biotype: protein_coding
description:
  Calcium/calmodulin-dependent protein kinase type II subunit alpha; Belongs to the protein kinase superfamily.


ensembl_gene_id: A0A1U7RYC4
symbol: LOC102374005
gene_biotype: protein_coding
description:
  Transient receptor potential cation channel subfamily V member 6-like isoform X1; Belongs to the transient receptor (TC 1.A.4) family.


ensembl_gene_id: A0A1U7RYE2
symbol: OXSM
gene_biotype: protein_coding
description:
  3-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: A0A1U7RYF5
symbol: PDHA1
gene_biotype: protein_coding
description:
  Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


ensembl_gene_id: A0A1U7RYR4
symbol: ARL5C
gene_biotype: protein_coding
description:
  Putative ADP-ribosylation factor-like protein 5C; Belongs to the small GTPase superfamily. Arf family.


ensembl_gene_id: A0A1U7RYS3
symbol: USP16
gene_biotype: protein_coding
description:
  Ubiquitin carboxyl-terminal hydrolase 16; Specifically deubiquitinates 'Lys-120' of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A is a prerequisite for subsequent phosphorylation at 'Ser-11' of histone H3 (H3S10ph), and is required for chromosome segregation when cells enter into mitosis. Regulates Hox gene expression via histone H2A deubiquitination. Prefers nucleosomal substrates. Does not deubiquitinate histone H2B.


ensembl_gene_id: A0A1U7RYT8
symbol: FUT8
gene_biotype: protein_coding
description:
  Alpha-(1,6)-fucosyltransferase; Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans. Belongs to the glycosyltransferase 23 family.


ensembl_gene_id: A0A1U7RZ04
symbol: LOC102381801
gene_biotype: protein_coding
description:
  Ectonucleoside triphosphate diphosphohydrolase 8-like isoform X1; Belongs to the GDA1/CD39 NTPase family.


ensembl_gene_id: A0A1U7RZ15
symbol: RHCG
gene_biotype: protein_coding
description:
  Ammonium transporter Rh type C; Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.


ensembl_gene_id: A0A1U7RZA5
symbol: GLRA2
gene_biotype: protein_coding
description:
  Glycine receptor subunit alpha-2 isoform X1; Belongs to the ligand-gated ion channel (TC 1.A.9) family.


ensembl_gene_id: A0A1U7RZH1
symbol: TNFSF10
gene_biotype: protein_coding
description:
  Tumor necrosis factor ligand superfamily member 10 isoform X1; Belongs to the tumor necrosis factor family.


ensembl_gene_id: A0A1U7RZH7
symbol: SLC2A2
gene_biotype: protein_coding
description:
  Solute carrier family 2, facilitated glucose transporter member 2; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.


ensembl_gene_id: A0A1U7RZJ0
symbol: GABRA2
gene_biotype: protein_coding
description:
  Gamma-aminobutyric acid receptor subunit alpha-2; Belongs to the ligand-gated ion channel (TC 1.A.9) family.


ensembl_gene_id: A0A1U7RZJ6
symbol: LOC102378857
gene_biotype: protein_coding
description:
  Fatty acid-binding protein, adipocyte; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.


ensembl_gene_id: A0A1U7RZK5
symbol: SUV39H1
gene_biotype: protein_coding
description:
  Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily.


ensembl_gene_id: A0A1U7RZK8
symbol: STAR
gene_biotype: protein_coding
description:
  Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone.


ensembl_gene_id: A0A1U7RZN6
symbol: PROSC
gene_biotype: protein_coding
description:
  Pyridoxal phosphate homeostasis protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'- phosphate (PLP), the active form of vitamin B6; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.


ensembl_gene_id: A0A1U7RZT0
symbol: IMMT
gene_biotype: protein_coding
description:
  MICOS complex subunit MIC60; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.


ensembl_gene_id: A0A1U7RZX5
symbol: ACAT2
gene_biotype: protein_coding
description:
  acetyl-CoA acetyltransferase, cytosolic isoform X1; Belongs to the thiolase-like superfamily. Thiolase family.


ensembl_gene_id: A0A1U7S037
symbol: LOC102378538
gene_biotype: protein_coding
description:
  5-phosphohydroxy-L-lysine phospho-lyase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: A0A1U7S0D3
symbol: ATG4D
gene_biotype: protein_coding
description:
  Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family.


ensembl_gene_id: A0A1U7S0F6
symbol: NDOR1
gene_biotype: protein_coding
description:
  NADPH-dependent diflavin oxidoreductase 1; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Transfers electrons from NADPH to the Fe/S cluster of CIAPIN1. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.


ensembl_gene_id: A0A1U7S0F7
symbol: KIF23
gene_biotype: protein_coding
description:
  Kinesin-like protein KIF23; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.


ensembl_gene_id: A0A1U7S0F8
symbol: DUSP22
gene_biotype: protein_coding
description:
  Dual specificity protein phosphatase 22 isoform X1; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.


ensembl_gene_id: A0A1U7S0N8
symbol: SCNN1G
gene_biotype: protein_coding
description:
  Amiloride-sensitive sodium channel subunit gamma; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.


ensembl_gene_id: A0A1U7S0Q3
symbol: ELOVL7
gene_biotype: protein_coding
description:
  Elongation of very long chain fatty acids protein 7; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs and C18:3(n-6)-CoAs. Also active toward C20:4-, C18:0-, C18:1-, C18:2- and C16:0-CoAs, and weakly toward C20:0-CoA. Little or no activity toward C22:0-, C24:0 [...]


ensembl_gene_id: A0A1U7S0Q8
symbol: FGF1
gene_biotype: protein_coding
description:
  Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]


ensembl_gene_id: A0A1U7S0R8
symbol: SEPT8
gene_biotype: protein_coding
description:
  Septin-8 isoform X1; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.


ensembl_gene_id: A0A1U7S0X9
symbol: GRK7
gene_biotype: protein_coding
description:
  G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.


ensembl_gene_id: A0A1U7S109
symbol: ELP3
gene_biotype: protein_coding
description:
  Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation.


ensembl_gene_id: A0A1U7S197
symbol: TOP2A
gene_biotype: protein_coding
description:
  DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.


ensembl_gene_id: A0A1U7S198
symbol: LOC102379284
gene_biotype: protein_coding
description:
  Arylamine N-acetyltransferase, pineal gland isozyme NAT-10-like; Belongs to the arylamine N-acetyltransferase family.


ensembl_gene_id: A0A1U7S1D4
symbol: EXOC6
gene_biotype: protein_coding
description:
  Exocyst complex component; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.


ensembl_gene_id: A0A1U7S1D7
symbol: KIF11
gene_biotype: protein_coding
description:
  Kinesin-like protein KIF11 isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.


ensembl_gene_id: A0A1U7S1E8
symbol: SFT2D2
gene_biotype: protein_coding
description:
  Vesicle transport protein; May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex. Belongs to the SFT2 family.


ensembl_gene_id: A0A1U7S1J6
symbol: MAP2K3
gene_biotype: protein_coding
description:
  Dual specificity mitogen-activated protein kinase kinase 3 isoform X1; Belongs to the protein kinase superfamily.


ensembl_gene_id: A0A1U7S1N2
symbol: ATG12
gene_biotype: protein_coding
description:
  Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.


ensembl_gene_id: A0A1U7S1P4
symbol: MED11
gene_biotype: protein_coding
description:
  Mediator of RNA polymerase II transcription subunit 11; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.


ensembl_gene_id: A0A1U7S1R6
symbol: TRPV3
gene_biotype: protein_coding
description:
  Transient receptor potential cation channel subfamily V member 3; Belongs to the transient receptor (TC 1.A.4) family.


ensembl_gene_id: A0A1U7S1T6
symbol: ADSS
gene_biotype: protein_coding
description:
  Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.


ensembl_gene_id: A0A1U7S1Z4
symbol: ST6GALNAC6
gene_biotype: protein_coding
description:
  alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6; Belongs to the glycosyltransferase 29 family.


ensembl_gene_id: A0A1U7S241
symbol: MAP2K5
gene_biotype: protein_coding
description:
  Dual specificity mitogen-activated protein kinase kinase 5 isoform X1; Belongs to the protein kinase superfamily.


ensembl_gene_id: A0A1U7S242
symbol: GINS4
gene_biotype: protein_coding
description:
  DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family.


ensembl_gene_id: A0A1U7S243
symbol: TUBB3
gene_biotype: protein_coding
description:
  Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.


ensembl_gene_id: A0A1U7S2D2
symbol: ENTPD6
gene_biotype: protein_coding
description:
  Ectonucleoside triphosphate diphosphohydrolase 6 isoform X1; Belongs to the GDA1/CD39 NTPase family.


ensembl_gene_id: A0A1U7S2F6
symbol: POLR3C
gene_biotype: protein_coding
description:
  RNA polymerase III subunit C3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: A0A1U7S2G3
symbol: RBM8A
gene_biotype: protein_coding
description:
  RNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs.


ensembl_gene_id: A0A1U7S2H0
symbol: COQ4
gene_biotype: protein_coding
description:
  Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family.


ensembl_gene_id: A0A1U7S2N2
symbol: ELOVL5
gene_biotype: protein_coding
description:
  Elongation of very long chain fatty acids protein 5; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. May participate to the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involv [...]


ensembl_gene_id: A0A1U7S2P5
symbol: SNF8
gene_biotype: protein_coding
description:
  Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family.


ensembl_gene_id: A0A1U7S2S8
symbol: TNFSF14
gene_biotype: protein_coding
description:
  Tumor necrosis factor ligand superfamily member 14 isoform X1; Belongs to the tumor necrosis factor family.


ensembl_gene_id: A0A1U7S2W7
symbol: CASQ2
gene_biotype: protein_coding
description:
  Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.


ensembl_gene_id: A0A1U7S321
symbol: LOC102383890
gene_biotype: protein_coding
description:
  CMP-N-acetylneuraminate-beta-galactosamide- alpha-2,3-sialyltransferase 2-like; Belongs to the glycosyltransferase 29 family.


ensembl_gene_id: A0A1U7S368
symbol: KCNK13
gene_biotype: protein_coding
description:
  Potassium channel subfamily K member 13; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.


ensembl_gene_id: A0A1U7S381
symbol: SCARA5
gene_biotype: protein_coding
description:
  Scavenger receptor class A member 5; Ferritin receptor that mediates non-transferrin-dependent delivery of iron. Mediates cellular uptake of ferritin-bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type-specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non- transferrin iron delivery pathways.


ensembl_gene_id: A0A1U7S393
symbol: SLC26A9
gene_biotype: protein_coding
description:
  Solute carrier family 26 member 9; DIDS- and thiosulfate- sensitive anion exchanger mediating chloride, sulfate and oxalate transport. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.


ensembl_gene_id: A0A1U7S3D0
symbol: PIGP
gene_biotype: protein_coding
description:
  Phosphatidylinositol N-acetylglucosaminyltransferase subunit P; Part of the complex catalyzing the transfer of N- acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.


ensembl_gene_id: A0A1U7S3G8
symbol: POLR3F
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase III subunit RPC6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs; Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family.


ensembl_gene_id: A0A1U7S3I8
symbol: ANAPC10
gene_biotype: protein_coding
description:
  Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.


ensembl_gene_id: A0A1U7S3N0
symbol: POLE2
gene_biotype: protein_coding
description:
  DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family.


ensembl_gene_id: A0A1U7S3Q2
symbol: MST1
gene_biotype: protein_coding
description:
  Hepatocyte growth factor-like protein isoform X1; Belongs to the peptidase S1 family. Plasminogen subfamily.


ensembl_gene_id: A0A1U7S3R7
symbol: NSUN2
gene_biotype: protein_coding
description:
  LOW QUALITY PROTEIN: tRNA (Cytosine(34)-C(5))-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.


ensembl_gene_id: A0A1U7S3S6
symbol: PFKM
gene_biotype: protein_coding
description:
  ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.


ensembl_gene_id: A0A1U7S3X1
symbol: TSEN2
gene_biotype: protein_coding
description:
  tRNA-splicing endonuclease subunit Sen2; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural [...]


ensembl_gene_id: A0A1U7S460
symbol: FES
gene_biotype: protein_coding
description:
  Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily.


ensembl_gene_id: A0A1U7S465
symbol: WDR76
gene_biotype: protein_coding
description:
  WD repeat-containing protein 76; Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC. Belongs to the WD repeat DDB2/WDR76 family.


ensembl_gene_id: A0A1U7S4C4
symbol: LOC102381592
gene_biotype: protein_coding
description:
  Kinesin-like protein KIF19; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.


ensembl_gene_id: A0A1U7S4K4
symbol: AK3
gene_biotype: protein_coding
description:
  GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.


ensembl_gene_id: A0A1U7S4L5
symbol: LOC102378986
gene_biotype: protein_coding
description:
  Major histocompatibility complex class I-related gene protein-like; Belongs to the MHC class I family.


ensembl_gene_id: A0A1U7S4N4
symbol: TOP1MT
gene_biotype: protein_coding
description:
  DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...]


ensembl_gene_id: A0A1U7S4N6
symbol: PIK3C2G
gene_biotype: protein_coding
description:
  Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma; Belongs to the PI3/PI4-kinase family.


ensembl_gene_id: A0A1U7S4Q8
symbol: LOC102373662
gene_biotype: protein_coding
description:
  Uncharacterized protein LOC102373662 isoform X1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: A0A1U7S557
symbol: DUSP4
gene_biotype: protein_coding
description:
  Dual specificity protein phosphatase 4; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.


ensembl_gene_id: A0A1U7S591
symbol: SLC25A15
gene_biotype: protein_coding
description:
  Mitochondrial ornithine transporter 1 isoform X1; Belongs to the mitochondrial carrier (TC 2.A.29) family.


ensembl_gene_id: A0A1U7S5B8
symbol: GABRR1
gene_biotype: protein_coding
description:
  Gamma-aminobutyric acid receptor subunit rho-1 isoform X1; Belongs to the ligand-gated ion channel (TC 1.A.9) family.


ensembl_gene_id: A0A1U7S5E8
symbol: PRKCD
gene_biotype: protein_coding
description:
  Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.


ensembl_gene_id: A0A1U7S5F5
symbol: MINOS1
gene_biotype: protein_coding
description:
  MICOS complex subunit MIC10; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.


ensembl_gene_id: A0A1U7S5G1
symbol: CHAC1
gene_biotype: protein_coding
description:
  Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.


ensembl_gene_id: A0A1U7S5H8
symbol: RGR
gene_biotype: protein_coding
description:
  RPE-retinal G protein-coupled receptor; Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.


ensembl_gene_id: A0A1U7S5J3
symbol: BMPR1A
gene_biotype: protein_coding
description:
  Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.


ensembl_gene_id: A0A1U7S5L3
symbol: NDUFS1
gene_biotype: protein_coding
description:
  NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial; Belongs to the complex I 75 kDa subunit family.


ensembl_gene_id: A0A1U7S5M4
symbol: OAT
gene_biotype: protein_coding
description:
  Ornithine aminotransferase, mitochondrial isoform X1; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: A0A1U7S5N0
symbol: EEF1AKMT2
gene_biotype: protein_coding
description:
  EEF1A lysine methyltransferase 2; Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-318'; Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM4 family.


ensembl_gene_id: A0A1U7S5N5
symbol: CDS2
gene_biotype: protein_coding
description:
  Phosphatidate cytidylyltransferase; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin.


ensembl_gene_id: A0A1U7S5S1
symbol: ADORA1
gene_biotype: protein_coding
description:
  Adenosine receptor A1; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family.


ensembl_gene_id: A0A1U7S5U5
symbol: SOD3
gene_biotype: protein_coding
description:
  Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family.


ensembl_gene_id: A0A1U7S5X9
symbol: PPIL4
gene_biotype: protein_coding
description:
  Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.


ensembl_gene_id: A0A1U7S613
symbol: ST8SIA4
gene_biotype: protein_coding
description:
  CMP-N-acetylneuraminate-poly-alpha-2, 8-sialyltransferase; Belongs to the glycosyltransferase 29 family.


ensembl_gene_id: A0A1U7S621
symbol: PIGM
gene_biotype: protein_coding
description:
  GPI mannosyltransferase 1; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN- acyl-PI during GPI precursor assembly.


ensembl_gene_id: A0A1U7S653
symbol: GTPBP4
gene_biotype: protein_coding
description:
  Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.


ensembl_gene_id: A0A1U7S6A3
symbol: MED20
gene_biotype: protein_coding
description:
  Mediator of RNA polymerase II transcription subunit 20; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.


ensembl_gene_id: A0A1U7S6F6
symbol: OPA1
gene_biotype: protein_coding
description:
  Dynamin-like 120 kDa protein, mitochondrial isoform X1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.


ensembl_gene_id: A0A1U7S6N5
symbol: SNRPC
gene_biotype: protein_coding
description:
  U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...]


ensembl_gene_id: A0A1U7S6Q2
symbol: LOC102375088
gene_biotype: protein_coding
description:
  Major histocompatibility complex class I-related gene protein-like isoform X1; Belongs to the MHC class I family.


ensembl_gene_id: A0A1U7S6Y2
symbol: TGFBR2
gene_biotype: protein_coding
description:
  Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.


ensembl_gene_id: A0A1U7S6Z4
symbol: LOC102385390
gene_biotype: protein_coding
description:
  Adenosine receptor A3; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family.


ensembl_gene_id: A0A1U7S7B8
symbol: METTL16
gene_biotype: protein_coding
description:
  U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; RNA N6-methyltransferase that methylates adenosine residues of a subset of RNAs and plays a key role in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6- methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure. In presence of S-adenosyl-L-methionine, binds the 3'-UTR region of MAT2A mRNA and specifical [...]


ensembl_gene_id: A0A1U7S7C5
symbol: KITLG
gene_biotype: protein_coding
description:
  Kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family.


ensembl_gene_id: A0A1U7S7F9
symbol: DHRS9
gene_biotype: protein_coding
description:
  Dehydrogenase/reductase SDR family member 9; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: A0A1U7S7J9
symbol: RHBG
gene_biotype: protein_coding
description:
  Ammonium transporter Rh type B; Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.


ensembl_gene_id: A0A1U7S7N8
symbol: LOC102381400
gene_biotype: protein_coding
description:
  Lysozyme; Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Belongs to the glycosyl hydrolase 22 family.


ensembl_gene_id: A0A1U7S7S5
symbol: AGO4
gene_biotype: protein_coding
description:
  Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs; Belongs to the argonaute family. Ago subfamily.


ensembl_gene_id: A0A1U7S7T7
symbol: LOC102378555
gene_biotype: protein_coding
description:
  Unconventional myosin-Ie-like; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.


ensembl_gene_id: A0A1U7S7U1
symbol: AARS
gene_biotype: protein_coding
description:
  LOW QUALITY PROTEIN: alanine--tRNA ligase, cytoplasmic; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.


ensembl_gene_id: A0A1U7S7Z2
symbol: GALNT18
gene_biotype: protein_coding
description:
  Polypeptide N-acetylgalactosaminyltransferase 18 isoform X1; Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.


ensembl_gene_id: A0A1U7S7Z9
symbol: HHATL
gene_biotype: protein_coding
description:
  Protein-cysteine N-palmitoyltransferase HHAT-like protein isoform X1; Belongs to the membrane-bound acyltransferase family.


ensembl_gene_id: A0A1U7S835
symbol: MYO1C
gene_biotype: protein_coding
description:
  Unconventional myosin-Ic isoform X2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.


ensembl_gene_id: A0A1U7S856
symbol: CACNG2
gene_biotype: protein_coding
description:
  Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.


ensembl_gene_id: A0A1U7S860
symbol: TRAPPC5
gene_biotype: protein_coding
description:
  Trafficking protein particle complex subunit 5; May play a role in vesicular transport from endoplasmic reticulum to Golgi.


ensembl_gene_id: A0A1U7S8B4
symbol: AK6
gene_biotype: protein_coding
description:
  Adenylate kinase isoenzyme 6; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation; Belongs to the adenylate kinase family. AK6 subfamily.


ensembl_gene_id: A0A1U7S8F7
symbol: LOC102384876
gene_biotype: protein_coding
description:
  Peptidoglycan-recognition protein; Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Involved in innate immunity.


ensembl_gene_id: A0A1U7S8J1
symbol: EIF3J
gene_biotype: protein_coding
description:
  Eukaryotic translation initiation factor 3 subunit J; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.


ensembl_gene_id: A0A1U7S8M0
symbol: LOC102375640
gene_biotype: protein_coding
description:
  Unconventional myosin-Vb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.


ensembl_gene_id: A0A1U7S8N8
symbol: LOC102378789
gene_biotype: protein_coding
description:
  Arylamine N-acetyltransferase, pineal gland isozyme NAT-3-like; Belongs to the arylamine N-acetyltransferase family.


ensembl_gene_id: A0A1U7S8X4
symbol: OSTC
gene_biotype: protein_coding
description:
  Oligosaccharyltransferase complex subunit; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All s [...]


ensembl_gene_id: A0A1U7S906
symbol: MED31
gene_biotype: protein_coding
description:
  Mediator of RNA polymerase II transcription subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.


ensembl_gene_id: A0A1U7S908
symbol: LOC102387857
gene_biotype: protein_coding
description:
  Myosin light chain kinase, smooth muscle-like isoform X1; Belongs to the protein kinase superfamily.


ensembl_gene_id: A0A1U7S930
symbol: LOC102373747
gene_biotype: protein_coding
description:
  Transient receptor potential cation channel subfamily V member 6-like; Belongs to the transient receptor (TC 1.A.4) family.


ensembl_gene_id: A0A1U7S932
symbol: PTH1R
gene_biotype: protein_coding
description:
  Parathyroid hormone/parathyroid hormone-related peptide receptor isoform X1; Belongs to the G-protein coupled receptor 2 family.


ensembl_gene_id: A0A1U7S951
symbol: SUPT4H1
gene_biotype: protein_coding
description:
  Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family.


ensembl_gene_id: A0A1U7S957
symbol: MED19
gene_biotype: protein_coding
description:
  Mediator of RNA polymerase II transcription subunit 19; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.


ensembl_gene_id: A0A1U7S9J2
symbol: GPC4
gene_biotype: protein_coding
description:
  Glypican-4 isoform X1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.


ensembl_gene_id: A0A1U7S9M0
symbol: KCNK10
gene_biotype: protein_coding
description:
  Potassium channel subfamily K member 10; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.


ensembl_gene_id: A0A1U7S9N5
symbol: EIF3M
gene_biotype: protein_coding
description:
  Eukaryotic translation initiation factor 3 subunit M; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.


ensembl_gene_id: A0A1U7S9U2
symbol: PRDM4
gene_biotype: protein_coding
description:
  PR domain zinc finger protein 4; May function as a transcription factor involved in cell differentiation.


ensembl_gene_id: A0A1U7S9U8
symbol: KATNA1
gene_biotype: protein_coding
description:
  Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.


ensembl_gene_id: A0A1U7S9V1
symbol: ATP5MG
gene_biotype: protein_coding
description:
  ATP synthase subunit; Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core, and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proto [...]


ensembl_gene_id: A0A1U7S9W6
symbol: LRP6
gene_biotype: protein_coding
description:
  Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.


ensembl_gene_id: A0A1U7SA43
symbol: PPP2R2B
gene_biotype: protein_coding
description:
  Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.


ensembl_gene_id: A0A1U7SA76
symbol: LOC102379716
gene_biotype: protein_coding
description:
  Mas-related G-protein coupled receptor member H-like; Belongs to the G-protein coupled receptor 1 family.


ensembl_gene_id: A0A1U7SAB1
symbol: HSD17B10
gene_biotype: protein_coding
description:
  3-hydroxyacyl-CoA dehydrogenase type-2 isoform X2; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: A0A1U7SAD0
symbol: BGN
gene_biotype: protein_coding
description:
  Biglycan; May be involved in collagen fiber assembly. Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.


ensembl_gene_id: A0A1U7SAM3
symbol: SLC9A3R2
gene_biotype: protein_coding
description:
  Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression.


ensembl_gene_id: A0A1U7SAQ8
symbol: LOC102376880
gene_biotype: protein_coding
description:
  Unconventional myosin-Vb-like isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.


ensembl_gene_id: A0A1U7SAR5
symbol: ADI1
gene_biotype: protein_coding
description:
  1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Also down-regulates cell migration mediated by MMP14. Belongs to the acireductone dioxygenase (ARD) family.


ensembl_gene_id: A0A1U7SAS7
symbol: EIF4E1B
gene_biotype: protein_coding
description:
  Eukaryotic translation initiation factor 4E type 1B; Belongs to the eukaryotic initiation factor 4E family.


ensembl_gene_id: A0A1U7SAX5
symbol: EBAG9
gene_biotype: protein_coding
description:
  Receptor-binding cancer antigen expressed on SiSo cells; May participate in suppression of cell proliferation and induces apoptotic cell death through activation of interleukin-1-beta converting enzyme (ICE)-like proteases.


ensembl_gene_id: A0A1U7SB00
symbol: PHKB
gene_biotype: protein_coding
description:
  Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I.


ensembl_gene_id: A0A1U7SB11
symbol: HADHA
gene_biotype: protein_coding
description:
  Trifunctional enzyme subunit alpha, mitochondrial; Belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: A0A1U7SB36
symbol: LOC102369184
gene_biotype: protein_coding
description:
  RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.


ensembl_gene_id: A0A1U7SB73
symbol: EIF3B
gene_biotype: protein_coding
description:
  Eukaryotic translation initiation factor 3 subunit B; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome; Belongs to the eIF-3 subunit B family.


ensembl_gene_id: A0A1U7SB91
symbol: ENTPD1
gene_biotype: protein_coding
description:
  Ectonucleoside triphosphate diphosphohydrolase 1 isoform X1; Belongs to the GDA1/CD39 NTPase family.


ensembl_gene_id: A0A1U7SB96
symbol: RBP2
gene_biotype: protein_coding
description:
  Retinol-binding protein 2; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.


ensembl_gene_id: A0A1U7SBE7
symbol: MRPL24
gene_biotype: protein_coding
description:
  39S ribosomal protein L24, mitochondrial isoform X1; Belongs to the universal ribosomal protein uL24 family.


ensembl_gene_id: A0A1U7SBU8
symbol: SLC24A4
gene_biotype: protein_coding
description:
  Sodium/potassium/calcium exchanger 4 isoform X1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.


ensembl_gene_id: A0A1U7SBY7
symbol: KIF24
gene_biotype: protein_coding
description:
  Kinesin-like protein KIF24; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.


ensembl_gene_id: A0A1U7SC22
symbol: IDH1
gene_biotype: protein_coding
description:
  Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.


ensembl_gene_id: A0A1U7SC59
symbol: SIAH1
gene_biotype: protein_coding
description:
  E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.


ensembl_gene_id: A0A1U7SC63
symbol: LONP2
gene_biotype: protein_coding
description:
  Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import; Belongs to the peptidase S16 family.


ensembl_gene_id: A0A1U7SC65
symbol: MC1R
gene_biotype: protein_coding
description:
  Melanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family.


ensembl_gene_id: A0A1U7SCA9
symbol: ROCK1
gene_biotype: protein_coding
description:
  Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.


ensembl_gene_id: A0A1U7SCG3
symbol: RTCB
gene_biotype: protein_coding
description:
  RNA-splicing ligase RtcB homolog; Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs.


ensembl_gene_id: A0A1U7SCH1
symbol: LOC102385256
gene_biotype: protein_coding
description:
  Sodium/potassium/calcium exchanger 2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.


ensembl_gene_id: A0A1U7SCI4
symbol: PCNA
gene_biotype: protein_coding
description:
  Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.


ensembl_gene_id: A0A1U7SCI6
symbol: LOC102373703
gene_biotype: protein_coding
description:
  MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.


ensembl_gene_id: A0A1U7SCJ8
symbol: PPME1
gene_biotype: protein_coding
description:
  Protein phosphatase methylesterase 1; Demethylates proteins that have been reversibly carboxymethylated.


ensembl_gene_id: A0A1U7SCJ9
symbol: PLN
gene_biotype: protein_coding
description:
  Cardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN.


ensembl_gene_id: A0A1U7SCP3
symbol: ATP5F1B
gene_biotype: protein_coding
description:
  ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.


ensembl_gene_id: A0A1U7SCS2
symbol: ADGRF5
gene_biotype: protein_coding
description:
  Adhesion G protein-coupled receptor F5 isoform X1; Belongs to the G-protein coupled receptor 2 family.


ensembl_gene_id: A0A1U7SCU3
symbol: LOC102377010
gene_biotype: protein_coding
description:
  Retinol-binding protein 1; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.


ensembl_gene_id: A0A1U7SD06
symbol: ATP5PF
gene_biotype: protein_coding
description:
  ATP synthase-coupling factor 6, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain; Belongs to the eukaryotic ATPase subunit F6 family.


ensembl_gene_id: A0A1U7SD07
symbol: CLP1
gene_biotype: protein_coding
description:
  Polyribonucleotide 5'-hydroxyl-kinase Clp1; Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; thi [...]


ensembl_gene_id: A0A1U7SD41
symbol: CEPT1
gene_biotype: protein_coding
description:
  Choline/ethanolaminephosphotransferase 1 isoform X1; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: A0A1U7SD64
symbol: NCAPH
gene_biotype: protein_coding
description:
  Condensin complex subunit 2; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes.


ensembl_gene_id: A0A1U7SDB7
symbol: LOC102382214
gene_biotype: protein_coding
description:
  Myosin heavy chain, skeletal muscle, adult-like; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.


ensembl_gene_id: A0A1U7SDC8
symbol: LOC102386129
gene_biotype: protein_coding
description:
  C-terminal-binding protein 2-like isoform X1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: A0A1U7SDF5
symbol: INS
gene_biotype: protein_coding
description:
  Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.


ensembl_gene_id: A0A1U7SDG7
symbol: CD40LG
gene_biotype: protein_coding
description:
  CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.


ensembl_gene_id: A0A1U7SDM8
symbol: LOC102380512
gene_biotype: protein_coding
description:
  LOW QUALITY PROTEIN: epidermal retinol dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: A0A1U7SDS9
symbol: KCND3
gene_biotype: protein_coding
description:
  Potassium voltage-gated channel subfamily D member 3 isoform X1; Belongs to the potassium channel family.


ensembl_gene_id: A0A1U7SDT2
symbol: LOC102385782
gene_biotype: protein_coding
description:
  Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.


ensembl_gene_id: A0A1U7SDV9
symbol: GABRA6
gene_biotype: protein_coding
description:
  Gamma-aminobutyric acid receptor subunit alpha-6; Belongs to the ligand-gated ion channel (TC 1.A.9) family.


ensembl_gene_id: A0A1U7SDW3
symbol: GSR
gene_biotype: protein_coding
description:
  Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.


ensembl_gene_id: A0A1U7SEA6
symbol: CSNK2B
gene_biotype: protein_coding
description:
  Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.


ensembl_gene_id: A0A1U7SEC5
symbol: ST3GAL2
gene_biotype: protein_coding
description:
  CMP-N-acetylneuraminate-beta-galactosamide- alpha-2,3-sialyltransferase 2; Belongs to the glycosyltransferase 29 family.


ensembl_gene_id: A0A1U7SEF8
symbol: NDUFA2
gene_biotype: protein_coding
description:
  NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.


ensembl_gene_id: A0A1U7SEH5
symbol: LOC102382101
gene_biotype: protein_coding
description:
  LOW QUALITY PROTEIN: tumor necrosis factor ligand superfamily member 10-like; Belongs to the tumor necrosis factor family.


ensembl_gene_id: A0A1U7SEH6
symbol: SCNN1A
gene_biotype: protein_coding
description:
  Amiloride-sensitive sodium channel subunit alpha isoform X1; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.


ensembl_gene_id: A0A1U7SEQ1
symbol: ATP5F1A
gene_biotype: protein_coding
description:
  ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.


ensembl_gene_id: A0A1U7SEU3
symbol: METTL1
gene_biotype: protein_coding
description:
  tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.


ensembl_gene_id: A0A1U7SEU7
symbol: LOC102386058
gene_biotype: protein_coding
description:
  LOW QUALITY PROTEIN: retinol dehydrogenase 16-like; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: A0A1U7SF36
symbol: GDI1
gene_biotype: protein_coding
description:
  Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.


ensembl_gene_id: A0A1U7SF53
symbol: DHRS7C
gene_biotype: protein_coding
description:
  Dehydrogenase/reductase SDR family member 7C; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: A0A1U7SF72
symbol: RBKS
gene_biotype: protein_coding
description:
  Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.


ensembl_gene_id: A0A1U7SFB8
symbol: LOC102378561
gene_biotype: protein_coding
description:
  Class I histocompatibility antigen, F10 alpha chain-like isoform X1; Belongs to the MHC class I family.


ensembl_gene_id: A0A1U7SFD8
symbol: MED18
gene_biotype: protein_coding
description:
  Mediator of RNA polymerase II transcription subunit 18; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.


ensembl_gene_id: A0A1U7SFH1
symbol: LOC102371062
gene_biotype: protein_coding
description:
  Fatty acid-binding protein, heart; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.


ensembl_gene_id: A0A1U7SFK4
symbol: SLC25A11
gene_biotype: protein_coding
description:
  Mitochondrial 2-oxoglutarate/malate carrier protein; Belongs to the mitochondrial carrier (TC 2.A.29) family.


ensembl_gene_id: A0A1U7SFV4
symbol: SLC25A25
gene_biotype: protein_coding
description:
  Calcium-binding mitochondrial carrier protein SCaMC-2 isoform X1; Belongs to the mitochondrial carrier (TC 2.A.29) family.


ensembl_gene_id: A0A1U7SG01
symbol: LOC102381244
gene_biotype: protein_coding
description:
  SURF1-like protein; Probably involved in the biogenesis of the COX complex. Belongs to the SURF1 family.


ensembl_gene_id: A0A1U7SG23
symbol: LOC102377201
gene_biotype: protein_coding
description:
  Uncharacterized protein LOC102377201; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: A0A1U7SG76
symbol: POLA2
gene_biotype: protein_coding
description:
  DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis.


ensembl_gene_id: A0A1U7SGA3
symbol: EIF3H
gene_biotype: protein_coding
description:
  Eukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.


ensembl_gene_id: A0A1U7SGJ0
symbol: PAN2
gene_biotype: protein_coding
description:
  PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent  [...]


ensembl_gene_id: A0A1U7SGT2
symbol: INHA
gene_biotype: protein_coding
description:
  Inhibin alpha chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition; Belongs to the TGF-beta family.


ensembl_gene_id: A0A1U7SGY8
symbol: VMA21
gene_biotype: protein_coding
description:
  Vacuolar ATPase assembly integral membrane protein VMA21; Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum; Belongs to the VMA21 family.


ensembl_gene_id: A0A1U7SHB3
symbol: BLOC1S6
gene_biotype: protein_coding
description:
  Biogenesis of lysosome-related organelles complex 1 subunit 6; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particular [...]


ensembl_gene_id: A0A1U7SHB6
symbol: PNP
gene_biotype: protein_coding
description:
  Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.


ensembl_gene_id: A0A1U7SHC6
symbol: SEC23B
gene_biotype: protein_coding
description:
  Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.


ensembl_gene_id: A0A1U7SHG7
symbol: SLC5A7
gene_biotype: protein_coding
description:
  High affinity choline transporter 1; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: A0A1U7SHK3
symbol: UTP11
gene_biotype: protein_coding
description:
  U3 small nucleolar RNA-associated protein 11; Involved in nucleolar processing of pre-18S ribosomal RNA.


ensembl_gene_id: A0A1U7SHK8
symbol: HMGCS2
gene_biotype: protein_coding
description:
  3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.


ensembl_gene_id: A0A1U7SHM5
symbol: RPSA
gene_biotype: protein_coding
description:
  40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Belongs to the universal ribosomal protein uS2 family.


ensembl_gene_id: A0A1U7SHU8
symbol: TDO2
gene_biotype: protein_coding
description:
  Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.


ensembl_gene_id: A0A1U7SHX7
symbol: KIF22
gene_biotype: protein_coding
description:
  Kinesin-like protein KIF22 isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.


ensembl_gene_id: A0A1U7SHY1
symbol: ADCY6
gene_biotype: protein_coding
description:
  Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.


ensembl_gene_id: A0A1U7SI05
symbol: RIOK3
gene_biotype: protein_coding
description:
  Serine/threonine-protein kinase RIO3; Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.


ensembl_gene_id: A0A1U7SIA9
symbol: DPM3
gene_biotype: protein_coding
description:
  Dolichol-phosphate mannosyltransferase subunit 3; Stabilizer subunit of the dolichol-phosphate mannose (DPM) synthase complex; tethers catalytic subunit to the ER. Belongs to the DPM3 family.


ensembl_gene_id: A0A1U7SID2
symbol: VPS28
gene_biotype: protein_coding
description:
  Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.


ensembl_gene_id: A0A1U7SIG2
symbol: DNMT3A
gene_biotype: protein_coding
description:
  DNA (Cytosine-5)-methyltransferase 3A isoform X1; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.


ensembl_gene_id: A0A1U7SIH9
symbol: NUP93
gene_biotype: protein_coding
description:
  Nuclear pore complex protein Nup93; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance; Belongs to the nucleoporin interacting component (NIC) family.


ensembl_gene_id: A0A1U7SII6
symbol: LOC102378992
gene_biotype: protein_coding
description:
  Uncharacterized protein LOC102378992 isoform X1; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: A0A1U7SIN4
symbol: LOC102377430
gene_biotype: protein_coding
description:
  Uncharacterized protein LOC102377430; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: A0A1U7SIP7
symbol: TSFM
gene_biotype: protein_coding
description:
  Elongation factor Ts, mitochondrial; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.


ensembl_gene_id: A0A1U7SIT8
symbol: GUCY1B1
gene_biotype: protein_coding
description:
  Guanylate cyclase soluble subunit beta-1 isoform X1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.


ensembl_gene_id: A0A1U7SIV0
symbol: PRKACA
gene_biotype: protein_coding
description:
  cAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily.


ensembl_gene_id: A0A1U7SJ62
symbol: ENSA
gene_biotype: protein_coding
description:
  Alpha-endosulfine; Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. Belongs to the endosulfine family.


ensembl_gene_id: A0A1U7SJE8
symbol: RPA1
gene_biotype: protein_coding
description:
  Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.


ensembl_gene_id: A0A1U7SJF4
symbol: KATNAL2
gene_biotype: protein_coding
description:
  Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.


ensembl_gene_id: A0A1U7SJF9
symbol: GMPR
gene_biotype: protein_coding
description:
  GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.


ensembl_gene_id: A0A1U7SJS6
symbol: LOC102372247
gene_biotype: protein_coding
description:
  LOW QUALITY PROTEIN: uncharacterized protein LOC102372247; Belongs to the intermediate filament family.


ensembl_gene_id: A0A1U7SJV7
symbol: LOC102387624
gene_biotype: protein_coding
description:
  Transient receptor potential cation channel subfamily V member 2 isoform X1; Belongs to the transient receptor (TC 1.A.4) family.


ensembl_gene_id: A0A1U7SJZ6
symbol: LOC102387399
gene_biotype: protein_coding
description:
  Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.


ensembl_gene_id: A0A1U7SKK8
symbol: SSR2
gene_biotype: protein_coding
description:
  Translocon-associated protein subunit beta; TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.


ensembl_gene_id: A0A1U7SKP2
symbol: THG1L
gene_biotype: protein_coding
description:
  tRNA(His) guanylyltransferase; Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage.


ensembl_gene_id: A0A1U7SKR8
symbol: MTAP
gene_biotype: protein_coding
description:
  S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.


ensembl_gene_id: A0A1U7SKU0
symbol: IMPDH1
gene_biotype: protein_coding
description:
  Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.


ensembl_gene_id: A0A1U7SL15
symbol: SLC2A12
gene_biotype: protein_coding
description:
  Solute carrier family 2, facilitated glucose transporter member 12 isoform X1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.


ensembl_gene_id: A0A1U7SL25
symbol: HADHB
gene_biotype: protein_coding
description:
  Trifunctional enzyme subunit beta, mitochondrial; Belongs to the thiolase-like superfamily. Thiolase family.


ensembl_gene_id: A0A1U7SL48
symbol: CDA
gene_biotype: protein_coding
description:
  Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.


ensembl_gene_id: A0A1U7SL62
symbol: APEX1
gene_biotype: protein_coding
description:
  DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.


ensembl_gene_id: A0A1U7SL70
symbol: LOC102379954
gene_biotype: protein_coding
description:
  Epidermal retinol dehydrogenase 2-like; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: A0A1U7SLB6
symbol: GABRG2
gene_biotype: protein_coding
description:
  Gamma-aminobutyric acid receptor subunit gamma-2; Belongs to the ligand-gated ion channel (TC 1.A.9) family.


ensembl_gene_id: A0A1U7SLD9
symbol: LOC102383590
gene_biotype: protein_coding
description:
  Kinesin-like protein KIF20B isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.


ensembl_gene_id: A0A1U7SLJ5
symbol: GTF2E2
gene_biotype: protein_coding
description:
  Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.


ensembl_gene_id: A0A1U7SLS2
symbol: FIS1
gene_biotype: protein_coding
description:
  Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering.


ensembl_gene_id: A0A1U7SLT2
symbol: EIF3E
gene_biotype: protein_coding
description:
  Eukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.


ensembl_gene_id: A0A1U7SLU7
symbol: ACLY
gene_biotype: protein_coding
description:
  ATP-citrate synthase; In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family.


ensembl_gene_id: A0A1U7SM30
symbol: PPOX
gene_biotype: protein_coding
description:
  Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.


ensembl_gene_id: A0A1U7SM75
symbol: SETD7
gene_biotype: protein_coding
description:
  Histone-lysine N-methyltransferase SETD7; Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes.


ensembl_gene_id: A0A1U7SME1
symbol: AMPD2
gene_biotype: protein_coding
description:
  AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.


ensembl_gene_id: A0A1U7SMH4
symbol: LOC102371161
gene_biotype: protein_coding
description:
  Multidrug and toxin extrusion protein; Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.


ensembl_gene_id: A0A1U7SMN6
symbol: POR
gene_biotype: protein_coding
description:
  NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5; In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.


ensembl_gene_id: A0A1U7SMS6
symbol: PHKG1
gene_biotype: protein_coding
description:
  Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform; Belongs to the protein kinase superfamily.


ensembl_gene_id: A0A1U7SMU9
symbol: POLE
gene_biotype: protein_coding
description:
  DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.


ensembl_gene_id: A0A1U7SMX8
symbol: NDUFS3
gene_biotype: protein_coding
description:
  NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial; Belongs to the complex I 30 kDa subunit family.


ensembl_gene_id: A0A1U7SN08
symbol: LOC102386213
gene_biotype: protein_coding
description:
  Epoxide hydrolase; Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. Belongs to the peptidase S33 family.


ensembl_gene_id: A0A1U7SN22
symbol: LOC102376346
gene_biotype: protein_coding
description:
  Cytochrome c oxidase subunit 6A2, mitochondrial; Belongs to the cytochrome c oxidase subunit 6A family.


ensembl_gene_id: A0A1U7SNC8
symbol: LOC102385138
gene_biotype: protein_coding
description:
  Interferon-induced GTP-binding protein Mx1-like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.


ensembl_gene_id: A0A1U7SNE5
symbol: ZNRD1
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.


ensembl_gene_id: A0A1U7SNK8
symbol: HIBCH
gene_biotype: protein_coding
description:
  3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: A0A1U7SNW2
symbol: GABRA1
gene_biotype: protein_coding
description:
  Gamma-aminobutyric acid receptor subunit alpha-1; Belongs to the ligand-gated ion channel (TC 1.A.9) family.


ensembl_gene_id: A0A1U7SNZ7
symbol: RDH5
gene_biotype: protein_coding
description:
  LOW QUALITY PROTEIN: 11-cis retinol dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: A0A1U7SP84
symbol: CCR9
gene_biotype: protein_coding
description:
  LOW QUALITY PROTEIN: C-C chemokine receptor type 9; Belongs to the G-protein coupled receptor 1 family.


ensembl_gene_id: A0A1U7SPB6
symbol: EHD4
gene_biotype: protein_coding
description:
  EH domain-containing protein 4; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.


ensembl_gene_id: A0A1U7SPC0
symbol: EIF2B4
gene_biotype: protein_coding
description:
  LOW QUALITY PROTEIN: translation initiation factor eIF-2B subunit delta; Belongs to the eIF-2B alpha/beta/delta subunits family.


ensembl_gene_id: A0A1U7SPH6
symbol: MYO1F
gene_biotype: protein_coding
description:
  Unconventional myosin-If; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.


ensembl_gene_id: A0A1U7SPK6
symbol: CIAO1
gene_biotype: protein_coding
description:
  Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Belongs to the WD repeat CIA1 family.


ensembl_gene_id: A0A1U7SPU1
symbol: SPA17
gene_biotype: protein_coding
description:
  Sperm surface protein Sp17; Sperm surface zona pellucida binding protein. Helps to bind spermatozoa to the zona pellucida with high affinity. Might function in binding zona pellucida and carbohydrates.


ensembl_gene_id: A0A1U7SQ41
symbol: MTCH2
gene_biotype: protein_coding
description:
  Mitochondrial carrier homolog 2 isoform X1; Belongs to the mitochondrial carrier (TC 2.A.29) family.


ensembl_gene_id: A0A1U7SQC9
symbol: GFM2
gene_biotype: protein_coding
description:
  Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.


ensembl_gene_id: A0A1U7SQG7
symbol: TAT
gene_biotype: protein_coding
description:
  Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate.


ensembl_gene_id: A0A1U7SR16
symbol: LOC102381022
gene_biotype: protein_coding
description:
  Uncharacterized protein LOC102381022; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: A0A1U7SR71
symbol: WARS
gene_biotype: protein_coding
description:
  tryptophan--tRNA ligase, cytoplasmic isoform X1; Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: A0A1U7SRA5
symbol: ENY2
gene_biotype: protein_coding
description:
  Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histones. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. The TREX-2 complex  [...]


ensembl_gene_id: A0A1U7SRK8
symbol: LOC102371169
gene_biotype: protein_coding
description:
  17-beta-hydroxysteroid dehydrogenase type 6-like; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: A0A1U7SS08
symbol: CIAPIN1
gene_biotype: protein_coding
description:
  Anamorsin; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1. NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electron [...]


ensembl_gene_id: A0A1U7SS29
symbol: PGAM2
gene_biotype: protein_coding
description:
  Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.


ensembl_gene_id: A0A1U7SS34
symbol: SLC20A1
gene_biotype: protein_coding
description:
  Phosphate transporter; Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport. Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.


ensembl_gene_id: A0A1U7SS44
symbol: PPIA
gene_biotype: protein_coding
description:
  Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.


ensembl_gene_id: A0A1U7SSK4
symbol: PIGK
gene_biotype: protein_coding
description:
  GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family.


ensembl_gene_id: A0A1U7SSX9
symbol: METAP2
gene_biotype: protein_coding
description:
  Methionine aminopeptidase 2; Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met- Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.


ensembl_gene_id: A0A1U7STF0
symbol: PTPN14
gene_biotype: protein_coding
description:
  Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily.


ensembl_gene_id: A0A1U7STY6
symbol: LOC102381202
gene_biotype: protein_coding
description:
  NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.


ensembl_gene_id: A0A1U7SU05
symbol: ZRANB2
gene_biotype: protein_coding
description:
  Zinc finger Ran-binding domain-containing protein 2; May interfere with constitutive 5'-splice site selection. Belongs to the ZRANB2 family.


ensembl_gene_id: A0A1U7SUE4
symbol: OSGEPL1
gene_biotype: protein_coding
description:
  Probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance.


ensembl_gene_id: A0A1U7SUQ5
symbol: KIF16B
gene_biotype: protein_coding
description:
  Kinesin-like protein KIF16B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.


ensembl_gene_id: A0A1U7SUV3
symbol: GNL2
gene_biotype: protein_coding
description:
  Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.


ensembl_gene_id: A0A1U7SUX6
symbol: CKMT2
gene_biotype: protein_coding
description:
  Creatine kinase S-type, mitochondrial isoform X1; Belongs to the ATP:guanido phosphotransferase family.


ensembl_gene_id: A0A1U7SV05
symbol: RNF168
gene_biotype: protein_coding
description:
  E3 ubiquitin-protein ligase RNF168; E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and ubiquitinates histone H2A and H2AX, leading to amplify the RNF8-dependent H2A ubiquitination and promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recrui [...]


ensembl_gene_id: A0A1U7SV55
symbol: GUCY1A1
gene_biotype: protein_coding
description:
  Guanylate cyclase soluble subunit alpha-1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.


ensembl_gene_id: A0A1U7SVJ7
symbol: LOC102367733
gene_biotype: protein_coding
description:
  Cytochrome b-c1 complex subunit 7; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain; Belongs to the UQCRB/QCR7 family.


ensembl_gene_id: A0A1U7SWC7
symbol: GTF2H4
gene_biotype: protein_coding
description:
  General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.


ensembl_gene_id: A0A1U7SWP8
symbol: ROR2
gene_biotype: protein_coding
description:
  LOW QUALITY PROTEIN: tyrosine-protein kinase transmembrane receptor ROR2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily.


ensembl_gene_id: A0A1U7SWQ0
symbol: RAG1
gene_biotype: protein_coding
description:
  V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break  [...]


ensembl_gene_id: A0A1U7SXA4
symbol: LOC102383910
gene_biotype: protein_coding
description:
  Uncharacterized protein LOC102383910; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.


ensembl_gene_id: A0A1U7SY24
symbol: LOC102381113
gene_biotype: protein_coding
description:
  Solute carrier family 2, facilitated glucose transporter member 9-like; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.


ensembl_gene_id: A0A1U7SYD7
symbol: COQ2
gene_biotype: protein_coding
description:
  4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.


ensembl_gene_id: A0A1U7SYI6
symbol: FABP7
gene_biotype: protein_coding
description:
  Fatty acid-binding protein, brain; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.


ensembl_gene_id: A0A1U8CU12
symbol: MYO5A
gene_biotype: protein_coding
description:
  Unconventional myosin-Va isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.


ensembl_gene_id: A0A1U8CU89
symbol: KIF26A
gene_biotype: protein_coding
description:
  Kinesin-like protein KIF26A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.


ensembl_gene_id: A0A1U8CV80
symbol: HSPA2
gene_biotype: protein_coding
description:
  LOW QUALITY PROTEIN: heat shock-related 70 kDa protein 2; Belongs to the heat shock protein 70 family.


ensembl_gene_id: A0A1U8CVH5
symbol: LOC102375680
gene_biotype: protein_coding
description:
  Ankyrin repeat domain-containing protein 65; Belongs to the bacterial ribosomal protein bL20 family.


ensembl_gene_id: A0A1U8CVK5
symbol: GABRR3
gene_biotype: protein_coding
description:
  Gamma-aminobutyric acid receptor subunit rho-3; Belongs to the ligand-gated ion channel (TC 1.A.9) family.


ensembl_gene_id: A0A1U8CVK8
symbol: DUSP27
gene_biotype: protein_coding
description:
  Inactive dual specificity phosphatase 27; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.


ensembl_gene_id: A0A1U8CVN3
symbol: GUCY1A2
gene_biotype: protein_coding
description:
  Guanylate cyclase soluble subunit alpha-2 isoform X2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.


ensembl_gene_id: A0A1U8CVV5
symbol: HSDL1
gene_biotype: protein_coding
description:
  Inactive hydroxysteroid dehydrogenase-like protein 1 isoform X1; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: A0A1U8CW18
symbol: MND1
gene_biotype: protein_coding
description:
  Meiotic nuclear division protein 1 homolog; Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis. Belongs to the MND1 family.


ensembl_gene_id: A0A1U8CWY2
symbol: LOC102371879
gene_biotype: protein_coding
description:
  TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...]


ensembl_gene_id: A0A1U8CX21
symbol: SIRT4
gene_biotype: protein_coding
description:
  NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily.


ensembl_gene_id: A0A1U8CX66
symbol: LOC106721969
gene_biotype: protein_coding
description:
  Solute carrier family 2, facilitated glucose transporter member 11-like isoform X1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.


ensembl_gene_id: A0A1U8CXC1
symbol: MPHOSPH10
gene_biotype: protein_coding
description:
  U3 small nucleolar ribonucleoprotein protein MPP10; Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing; Belongs to the MPP10 family.


ensembl_gene_id: A0A1U8CXE0
symbol: FAN1
gene_biotype: protein_coding
description:
  Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.


ensembl_gene_id: A0A1U8CXG1
symbol: SLC24A1
gene_biotype: protein_coding
description:
  Sodium/potassium/calcium exchanger 1 isoform X1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.


ensembl_gene_id: A0A1U8CY58
symbol: NBN
gene_biotype: protein_coding
description:
  Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis.


ensembl_gene_id: A0A1U8CY64
symbol: LARS2
gene_biotype: protein_coding
description:
  Probable leucine--tRNA ligase, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: A0A1U8CY73
symbol: KIF15
gene_biotype: protein_coding
description:
  Kinesin-like protein KIF15; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.


ensembl_gene_id: A0A1U8CYJ9
symbol: LOC102386707
gene_biotype: protein_coding
description:
  Solute carrier family 2, facilitated glucose transporter member 11-like; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.


ensembl_gene_id: A0A1U8CYS1
symbol: PRMT7
gene_biotype: protein_coding
description:
  Protein arginine N-methyltransferase; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s. Plays a role in gene imprinting by being r [...]


ensembl_gene_id: A0A1U8CYS6
symbol: ATP6V0E1
gene_biotype: protein_coding
description:
  V-type proton ATPase subunit; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.


ensembl_gene_id: A0A1U8CYV5
symbol: PDGFRB
gene_biotype: protein_coding
description:
  Platelet-derived growth factor receptor beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.


ensembl_gene_id: A0A1U8CZF0
symbol: COMT
gene_biotype: protein_coding
description:
  Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones.


ensembl_gene_id: A0A1U8CZJ7
symbol: ADGRL4
gene_biotype: protein_coding
description:
  Adhesion G protein-coupled receptor L4 isoform X1; Belongs to the G-protein coupled receptor 2 family.


ensembl_gene_id: A0A1U8CZN1
symbol: GABRA4
gene_biotype: protein_coding
description:
  LOW QUALITY PROTEIN: gamma-aminobutyric acid receptor subunit alpha-4; Belongs to the ligand-gated ion channel (TC 1.A.9) family.


ensembl_gene_id: A0A1U8D073
symbol: MDN1
gene_biotype: protein_coding
description:
  Midasin; Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits; Belongs to the midasin family.


ensembl_gene_id: A0A1U8D0E4
symbol: QTRT2
gene_biotype: protein_coding
description:
  Queuine tRNA-ribosyltransferase accessory subunit 2; Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine); Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily.


ensembl_gene_id: A0A1U8D0P2
symbol: DIS3L2
gene_biotype: protein_coding
description:
  DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation. Belongs to the RNR ribonuclease family. DIS3L2 subfamily.


ensembl_gene_id: A0A1U8D0V1
symbol: XRN2
gene_biotype: protein_coding
description:
  5'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II.


ensembl_gene_id: A0A1U8D0V4
symbol: LOC102381382
gene_biotype: protein_coding
description:
  Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.


ensembl_gene_id: A0A1U8D0X3
symbol: VPS29
gene_biotype: protein_coding
description:
  Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.


ensembl_gene_id: A0A1U8D1Z4
symbol: ST3GAL4
gene_biotype: protein_coding
description:
  CMP-N-acetylneuraminate-beta-galactosamide- alpha-2,3-sialyltransferase 4 isoform X1; Belongs to the glycosyltransferase 29 family.


ensembl_gene_id: A0A1U8D276
symbol: SLC25A23
gene_biotype: protein_coding
description:
  Calcium-binding mitochondrial carrier protein SCaMC-3; Belongs to the mitochondrial carrier (TC 2.A.29) family.


ensembl_gene_id: A0A1U8D293
symbol: MRI1
gene_biotype: protein_coding
description:
  Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.


ensembl_gene_id: A0A1U8D2F3
symbol: APAF1
gene_biotype: protein_coding
description:
  Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.


ensembl_gene_id: A0A1U8D2Q9
symbol: GDA
gene_biotype: protein_coding
description:
  Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.


ensembl_gene_id: A0A1U8D370
symbol: LOC102388601
gene_biotype: protein_coding
description:
  Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...]


ensembl_gene_id: A0A1U8D3U3
symbol: SEPSECS
gene_biotype: protein_coding
description:
  O-phosphoseryl-tRNA(Sec) selenium transferase; Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl- tRNA(Sec) required for selenoprotein biosynthesis.


ensembl_gene_id: A0A1U8D457
symbol: ATE1
gene_biotype: protein_coding
description:
  Arginyl-tRNA--protein transferase 1; Involved in the post-translational conjugation of arginine to the N-terminal aspartate or glutamate of a protein. This arginylation is required for degradation of the protein via the ubiquitin pathway. Belongs to the R-transferase family.


ensembl_gene_id: A0A1U8D466
symbol: SLC25A39
gene_biotype: protein_coding
description:
  Solute carrier family 25 member 39 isoform X1; Belongs to the mitochondrial carrier (TC 2.A.29) family.


ensembl_gene_id: A0A1U8D4Q8
symbol: KIF14
gene_biotype: protein_coding
description:
  Kinesin-like protein KIF14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.


ensembl_gene_id: A0A1U8D536
symbol: CFTR
gene_biotype: protein_coding
description:
  Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.


ensembl_gene_id: A0A1U8D5E2
symbol: LOC102375433
gene_biotype: protein_coding
description:
  Potassium channel subfamily K member 17; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.


ensembl_gene_id: A0A1U8D5E4
symbol: FEN1
gene_biotype: protein_coding
description:
  Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as  [...]


ensembl_gene_id: A0A1U8D5J6
symbol: DHRS7B
gene_biotype: protein_coding
description:
  Dehydrogenase/reductase SDR family member 7B isoform X1; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: A0A1U8D5K0
symbol: PEMT
gene_biotype: protein_coding
description:
  Phosphatidylethanolamine N-methyltransferase; Catalyzes the three sequential steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME), PMME to phosphatidyldimethylethanolamine (PDME), and PDME to phosphatidylcholine (PC); Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family.


ensembl_gene_id: A0A1U8D5U2
symbol: ATXN7L3
gene_biotype: protein_coding
description:
  Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates histone H2B. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription.


ensembl_gene_id: A0A1U8D608
symbol: TRMT2B
gene_biotype: protein_coding
description:
  LOW QUALITY PROTEIN: tRNA (Uracil(54)-C(5))-methyltransferase homolog; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.


ensembl_gene_id: A0A1U8D652
symbol: KIT
gene_biotype: protein_coding
description:
  Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.


ensembl_gene_id: A0A1U8D677
symbol: LOC102370299
gene_biotype: protein_coding
description:
  LOW QUALITY PROTEIN: galanin receptor type 1-like; Belongs to the G-protein coupled receptor 1 family.


ensembl_gene_id: A0A1U8D6C0
symbol: DPM1
gene_biotype: protein_coding
description:
  Dolichol-phosphate mannosyltransferase subunit 1; Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins.


ensembl_gene_id: A0A1U8D6D7
symbol: AVPR1B
gene_biotype: protein_coding
description:
  Vasopressin V1b receptor; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.


ensembl_gene_id: A0A1U8D6F1
symbol: PIK3C2B
gene_biotype: protein_coding
description:
  Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta isoform X1; Belongs to the PI3/PI4-kinase family.


ensembl_gene_id: A0A1U8D6S4
symbol: AGO3
gene_biotype: protein_coding
description:
  Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs; Belongs to the argonaute family. Ago subfamily.


ensembl_gene_id: A0A1U8D6X5
symbol: NTHL1
gene_biotype: protein_coding
description:
  Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family.


ensembl_gene_id: A0A1U8D6Y3
symbol: AARS2
gene_biotype: protein_coding
description:
  LOW QUALITY PROTEIN: alanine--tRNA ligase, mitochondrial; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. Belongs to the class-II aminoacyl-tRNA synthetase family.


ensembl_gene_id: A0A1U8D6Y9
symbol: LOC106721894
gene_biotype: protein_coding
description:
  Potassium channel subfamily K member 16-like; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.


ensembl_gene_id: A0A1U8D724
symbol: PDHB
gene_biotype: protein_coding
description:
  Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.


ensembl_gene_id: A0A1U8D7F0
symbol: FLT3
gene_biotype: protein_coding
description:
  Receptor-type tyrosine-protein kinase FLT3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.


ensembl_gene_id: A0A1U8D7H8
symbol: UBR3
gene_biotype: protein_coding
description:
  E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.


ensembl_gene_id: A0A1U8D7N8
symbol: NDUFA6
gene_biotype: protein_coding
description:
  NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 isoform X1; Belongs to the complex I LYR family.


ensembl_gene_id: A0A1U8D7Y1
symbol: VIPR1
gene_biotype: protein_coding
description:
  Vasoactive intestinal polypeptide receptor 1 isoform X1; Belongs to the G-protein coupled receptor 2 family.


ensembl_gene_id: A0A1U8D8B9
symbol: LOC102368266
gene_biotype: protein_coding
description:
  LOW QUALITY PROTEIN: heat shock 70 kDa protein 1A-like; Belongs to the heat shock protein 70 family.


ensembl_gene_id: A0A1U8D8P5
symbol: HSD17B12
gene_biotype: protein_coding
description:
  Very-long-chain 3-oxoacyl-CoA reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: A0A1U8D8T3
symbol: LOC102382057
gene_biotype: protein_coding
description:
  Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the low-voltage activated (LVA) group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...]


ensembl_gene_id: A0A1U8D968
symbol: CSF1R
gene_biotype: protein_coding
description:
  Macrophage colony-stimulating factor 1 receptor isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.


ensembl_gene_id: A0A1U8D9F7
symbol: LOC102374825
gene_biotype: protein_coding
description:
  LOW QUALITY PROTEIN: platelet-activating factor receptor-like; Belongs to the G-protein coupled receptor 1 family.


ensembl_gene_id: A0A1U8D9N5
symbol: CLTCL1
gene_biotype: protein_coding
description:
  Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.


ensembl_gene_id: A0A1U8DA53
symbol: LOC102377904
gene_biotype: protein_coding
description:
  Mitochondrial import inner membrane translocase subunit TIM23; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.


ensembl_gene_id: A0A1U8DAE7
symbol: AP4M1
gene_biotype: protein_coding
description:
  LOW QUALITY PROTEIN: AP-4 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.


ensembl_gene_id: A0A1U8DAU9
symbol: PGD
gene_biotype: protein_coding
description:
  6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.


ensembl_gene_id: A0A1U8DB40
symbol: MED4
gene_biotype: protein_coding
description:
  Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.


ensembl_gene_id: A0A1U8DB77
symbol: LOC102379211
gene_biotype: protein_coding
description:
  Growth hormone secretagogue receptor type 1-like; Belongs to the G-protein coupled receptor 1 family.


ensembl_gene_id: A0A1U8DBE0
symbol: NUP35
gene_biotype: protein_coding
description:
  Nucleoporin NUP53; Functions as a component of the nuclear pore complex (NPC). Belongs to the Nup35 family.


ensembl_gene_id: A0A1U8DBF3
symbol: MGME1
gene_biotype: protein_coding
description:
  Mitochondrial genome maintenance exonuclease 1; Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance. Has preference for 5'-3' exonuclease activity. Necessary for maintenance of proper 7S DNA levels. Probably involved in mitochondrial DNA (mtDNA) repair. Belongs to the MGME1 family.


ensembl_gene_id: A0A1U8DBH7
symbol: HACD2
gene_biotype: protein_coding
description:
  Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors  [...]


ensembl_gene_id: A0A1U8DBK4
symbol: SLC44A5
gene_biotype: protein_coding
description:
  Choline transporter-like protein 5 isoform X1; Belongs to the CTL (choline transporter-like) family.


ensembl_gene_id: A0A1U8DBN2
symbol: KCNK12
gene_biotype: protein_coding
description:
  Potassium channel subfamily K member 12; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.


ensembl_gene_id: A0A1U8DBQ6
symbol: MAP4K5
gene_biotype: protein_coding
description:
  Non-specific serine/threonine protein kinase; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.


ensembl_gene_id: A0A1U8DBV9
symbol: HPS5
gene_biotype: protein_coding
description:
  Hermansky-Pudlak syndrome 5 protein homolog; May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules.


ensembl_gene_id: A0A1U8DC28
symbol: COPZ2
gene_biotype: protein_coding
description:
  Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.


ensembl_gene_id: A0A1U8DCC6
symbol: GTF2F1
gene_biotype: protein_coding
description:
  Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.


ensembl_gene_id: A0A1U8DDK9
symbol: ABAT
gene_biotype: protein_coding
description:
  4-aminobutyrate aminotransferase, mitochondrial isoform X1; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: A0A1U8DDR5
symbol: FTSJ1
gene_biotype: protein_coding
description:
  Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase; Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs.


ensembl_gene_id: A0A1U8DDU3
symbol: LOC102370007
gene_biotype: protein_coding
description:
  LOW QUALITY PROTEIN: uncharacterized protein LOC102370007; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: A0A1U8DDU5
symbol: RRM1
gene_biotype: protein_coding
description:
  Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.


ensembl_gene_id: A0A1U8DDY2
symbol: MDM4
gene_biotype: protein_coding
description:
  Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family.


ensembl_gene_id: A0A1U8DES7
symbol: SLC5A8
gene_biotype: protein_coding
description:
  Sodium-coupled monocarboxylate transporter 1; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: A0A1U8DEZ2
symbol: DPH1
gene_biotype: protein_coding
description:
  2-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2.


ensembl_gene_id: A0A1U8DFF0
symbol: GUSB
gene_biotype: protein_coding
description:
  Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family.


ensembl_gene_id: A0A1U8DFM9
symbol: PPP1R3C
gene_biotype: protein_coding
description:
  Protein phosphatase 1 regulatory subunit 3C; Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown.


ensembl_gene_id: A0A1U8DFQ5
symbol: AMT
gene_biotype: protein_coding
description:
  Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.


ensembl_gene_id: A0A1U8DFZ0
symbol: LEP
gene_biotype: protein_coding
description:
  Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. Belongs to the leptin family.


ensembl_gene_id: A0A1U8DGR7
symbol: MYO9A
gene_biotype: protein_coding
description:
  Unconventional myosin-IXa isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.


ensembl_gene_id: A0A1U8DGZ4
symbol: LOC102379965
gene_biotype: protein_coding
description:
  Cytochrome c, somatic-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.


ensembl_gene_id: A0A1U8DH80
symbol: PIP4P2
gene_biotype: protein_coding
description:
  Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P).


ensembl_gene_id: A0A1U8DHE6
symbol: GYS2
gene_biotype: protein_coding
description:
  Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan.


ensembl_gene_id: A0A1U8DHH7
symbol: AGO2
gene_biotype: protein_coding
description:
  Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]


ensembl_gene_id: A0A1U8DHP2
symbol: TMSB15B
gene_biotype: protein_coding
description:
  Thymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family.


ensembl_gene_id: A0A1U8DHU0
symbol: HGF
gene_biotype: protein_coding
description:
  Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.


ensembl_gene_id: A0A1U8DI20
symbol: EHD1
gene_biotype: protein_coding
description:
  EH domain-containing protein 1 isoform X1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.


ensembl_gene_id: A0A1U8DIJ1
symbol: MX1
gene_biotype: protein_coding
description:
  Interferon-induced GTP-binding protein Mx1 isoform X1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.


ensembl_gene_id: A0A1U8DIK2
symbol: LMF2
gene_biotype: protein_coding
description:
  Lipase maturation factor; Involved in the maturation of specific proteins in the endoplasmic reticulum; Belongs to the lipase maturation factor family.


ensembl_gene_id: A0A1U8DIL2
symbol: GPC3
gene_biotype: protein_coding
description:
  Glypican-3 isoform X1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.


ensembl_gene_id: A0A1U8DIM1
symbol: PLSCR1
gene_biotype: protein_coding
description:
  Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family.


ensembl_gene_id: A0A1U8DIS9
symbol: MED21
gene_biotype: protein_coding
description:
  Mediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.


ensembl_gene_id: A0A1U8DJ44
symbol: AGPAT2
gene_biotype: protein_coding
description:
  1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.


ensembl_gene_id: A0A1U8DJ58
symbol: NSUN6
gene_biotype: protein_coding
description:
  Putative methyltransferase NSUN6 isoform X1; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.


ensembl_gene_id: A0A1U8DJG0
symbol: LOC102387880
gene_biotype: protein_coding
description:
  LOW QUALITY PROTEIN: trace amine-associated receptor 9-like; Belongs to the G-protein coupled receptor 1 family.


ensembl_gene_id: A0A1U8DJJ5
symbol: EHD3
gene_biotype: protein_coding
description:
  EH domain-containing protein 3 isoform X1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.


ensembl_gene_id: A0A1U8DJK3
symbol: AGPS
gene_biotype: protein_coding
description:
  Alkylglycerone-phosphate synthase; Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids; Belongs to the FAD-binding oxidoreductase/transferase type 4 family.


ensembl_gene_id: A0A1U8DK58
symbol: MYO7B
gene_biotype: protein_coding
description:
  Unconventional myosin-VIIb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.


ensembl_gene_id: A0A1U8DK77
symbol: MYO19
gene_biotype: protein_coding
description:
  Unconventional myosin-XIX isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.


ensembl_gene_id: A0A1U8DK88
symbol: PRMT5
gene_biotype: protein_coding
description:
  Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily.


ensembl_gene_id: A0A1U8DKU3
symbol: MYO9B
gene_biotype: protein_coding
description:
  Unconventional myosin-IXb isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.


ensembl_gene_id: A0A1U8DKW9
symbol: PGS1
gene_biotype: protein_coding
description:
  CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin; Belongs to the CDP-alcohol phosphatidyltransferase class-II family.


ensembl_gene_id: A0A1U8DLQ1
symbol: TARBP2
gene_biotype: protein_coding
description:
  RISC-loading complex subunit TARBP2; Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from [...]


ensembl_gene_id: A0A1U8DLQ2
symbol: ARCN1
gene_biotype: protein_coding
description:
  Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.


ensembl_gene_id: A0A1U8DLW7
symbol: SNRPE
gene_biotype: protein_coding
description:
  Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family.


ensembl_gene_id: A0A1U8DLZ2
symbol: FPGS
gene_biotype: protein_coding
description:
  Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.


ensembl_gene_id: A0A1U8DM01
symbol: LOC102372691
gene_biotype: protein_coding
description:
  Myosin heavy chain, skeletal muscle, adult; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.


ensembl_gene_id: A0A1U8DM61
symbol: COPA
gene_biotype: protein_coding
description:
  Coatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.


ensembl_gene_id: A0A1U8DMC5
symbol: CCR8
gene_biotype: protein_coding
description:
  LOW QUALITY PROTEIN: C-C chemokine receptor type 8; Belongs to the G-protein coupled receptor 1 family.


ensembl_gene_id: A0A1U8DME1
symbol: TNFSF13B
gene_biotype: protein_coding
description:
  Tumor necrosis factor ligand superfamily member 13B isoform X1; Belongs to the tumor necrosis factor family.


ensembl_gene_id: A0A1U8DMW6
symbol: CAPZB
gene_biotype: protein_coding
description:
  F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.


ensembl_gene_id: A0A1U8DN21
symbol: LOC102384161
gene_biotype: protein_coding
description:
  Uncharacterized protein LOC102384161; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.


ensembl_gene_id: A0A1U8DNT7
symbol: RP2
gene_biotype: protein_coding
description:
  Protein XRP2; Acts as a GTPase-activating protein (GAP) for tubulin in concert with tubulin-specific chaperone C, but does not enhance tubulin heterodimerization.


ensembl_gene_id: A0A1U8DNU1
symbol: POLM
gene_biotype: protein_coding
description:
  DNA-directed DNA/RNA polymerase mu; Gap-filling polymerase involved in repair of DNA double- strand breaks by non-homologous end joining (NHEJ). Belongs to the DNA polymerase type-X family.


ensembl_gene_id: A0A1U8DNX9
symbol: MYO1G
gene_biotype: protein_coding
description:
  Unconventional myosin-Ig; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.


ensembl_gene_id: A0A1U8DNY3
symbol: PTK2B
gene_biotype: protein_coding
description:
  Protein-tyrosine kinase 2-beta isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family.


ensembl_gene_id: A0A1U8DP40
symbol: LOC102380799
gene_biotype: protein_coding
description:
  Stress-associated endoplasmic reticulum protein; May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation. Belongs to the RAMP4 family.


ensembl_gene_id: A0A1U8DPA2
symbol: LOC106723349
gene_biotype: protein_coding
description:
  LOW QUALITY PROTEIN: olfactory receptor 13G1-like; Belongs to the G-protein coupled receptor 1 family.


ensembl_gene_id: A0A1U8DPB4
symbol: LOC102369097
gene_biotype: protein_coding
description:
  LOW QUALITY PROTEIN: short transient receptor potential channel 2-like; Belongs to the transient receptor (TC 1.A.4) family.


ensembl_gene_id: A0A1U8DPS2
symbol: LOC102379374
gene_biotype: protein_coding
description:
  LOW QUALITY PROTEIN: putative cation exchanger C521.04c; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.


ensembl_gene_id: A0A1U8DPV0
symbol: ALG3
gene_biotype: protein_coding
description:
  Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase; Adds the first Dol-P-Man derived mannose in an alpha-1,3 linkage to Man(5)GlcNAc(2)-PP-Dol.


ensembl_gene_id: A0A1U8DQ23
symbol: VPS16
gene_biotype: protein_coding
description:
  Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.


ensembl_gene_id: A0A1U8DQB8
symbol: MOCS2
gene_biotype: protein_coding
description:
  Molybdopterin synthase sulfur carrier subunit; Acts as a sulfur carrier required for molybdopterin biosynthesis. Component of the molybdopterin synthase complex that catalyzes the conversion of precursor Z into molybdopterin by mediating the incorporation of 2 sulfur atoms into precursor Z to generate a dithiolene group. In the complex, serves as sulfur donor by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. After interaction with MOCS2B, the sulfur is then transferred to precursor Z to form molybdopterin; Belongs to the MoaD family. MOCS2A subfamily.


ensembl_gene_id: A0A1U8DQK0
symbol: LOC102377785
gene_biotype: protein_coding
description:
  Calcium/calmodulin-dependent protein kinase type IV-like; Belongs to the protein kinase superfamily.


ensembl_gene_id: A0A1U8DR59
symbol: CNP
gene_biotype: protein_coding
description:
  2',3'-cyclic-nucleotide 3'-phosphodiesterase; May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin; Belongs to the 2H phosphoesterase superfamily. CNPase family.


ensembl_gene_id: A0A1U8DR88
symbol: KDM1A
gene_biotype: protein_coding
description:
  Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.


ensembl_gene_id: A0A1U8DRD6
symbol: GABRG3
gene_biotype: protein_coding
description:
  Gamma-aminobutyric acid receptor subunit gamma-3; Belongs to the ligand-gated ion channel (TC 1.A.9) family.


ensembl_gene_id: A0A1U8DS06
symbol: IARS
gene_biotype: protein_coding
description:
  isoleucine--tRNA ligase, cytoplasmic isoform X1; Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: A0A1U8DS52
symbol: CPT1B
gene_biotype: protein_coding
description:
  Carnitine O-palmitoyltransferase 1, muscle isoform isoform X1; Belongs to the carnitine/choline acetyltransferase family.


ensembl_gene_id: A0A1U8DTA4
symbol: ORC1
gene_biotype: protein_coding
description:
  Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.


ensembl_gene_id: A0A1U8DTG7
symbol: XPOT
gene_biotype: protein_coding
description:
  Exportin-T; tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Belongs to the exportin family.


ensembl_gene_id: A0A1U8DUC0
symbol: SDAD1
gene_biotype: protein_coding
description:
  Protein SDA1; Required for 60S pre-ribosomal subunits export to the cytoplasm; Belongs to the SDA1 family.


ensembl_gene_id: A0A1U8DUL8
symbol: LOC102370921
gene_biotype: protein_coding
description:
  Retinol dehydrogenase 7-like isoform X1; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: A0A1U8DV16
symbol: LOC102374268
gene_biotype: protein_coding
description:
  LOW QUALITY PROTEIN: D(1C) dopamine receptor-like; Belongs to the G-protein coupled receptor 1 family.


ensembl_gene_id: A0A1U8DV32
symbol: AGXT2
gene_biotype: protein_coding
description:
  Alanine--glyoxylate aminotransferase 2, mitochondrial; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: A0A1U8DVJ8
symbol: NDUFV1
gene_biotype: protein_coding
description:
  NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain.


ensembl_gene_id: A0A1U8DW86
symbol: PTPN6
gene_biotype: protein_coding
description:
  Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.


ensembl_gene_id: A0A1U8DWC6
symbol: PRLR
gene_biotype: protein_coding
description:
  Prolactin receptor; This is a receptor for the anterior pituitary hormone prolactin; Belongs to the type I cytokine receptor family. Type 1 subfamily.


ensembl_gene_id: A0A1U8DX09
symbol: MYO1B
gene_biotype: protein_coding
description:
  Unconventional myosin-Ib; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.


ensembl_gene_id: A0A1U8DX28
symbol: SLC40A1
gene_biotype: protein_coding
description:
  Solute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily.


ensembl_gene_id: A0A1U8DXL1
symbol: BLVRA
gene_biotype: protein_coding
description:
  Biliverdin reductase A; Reduces the gamma-methene bridge of the open tetrapyrrole, biliverdin IX alpha, to bilirubin with the concomitant oxidation of a NADH or NADPH cofactor; Belongs to the Gfo/Idh/MocA family. Biliverdin reductase subfamily.


ensembl_gene_id: A0A1U8DXL5
symbol: KIF25
gene_biotype: protein_coding
description:
  Kinesin-like protein KIF25; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.


ensembl_gene_id: A0A1U8DY57
symbol: LOC102378834
gene_biotype: protein_coding
description:
  Eukaryotic translation initiation factor 1A, Y-chromosomal; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.


ensembl_gene_id: A0A1U8DYC1
symbol: VPS11
gene_biotype: protein_coding
description:
  Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family.


ensembl_gene_id: A0A1U8DYL9
symbol: GPR171
gene_biotype: protein_coding
description:
  LOW QUALITY PROTEIN: probable G-protein coupled receptor 171; Belongs to the G-protein coupled receptor 1 family.


ensembl_gene_id: A0A1U8E0I2
symbol: PEX12
gene_biotype: protein_coding
description:
  Peroxisome assembly protein 12; Required for protein import into peroxisomes. Belongs to the pex2/pex10/pex12 family.


ensembl_gene_id: A0A1U8E0K2
symbol: GRIN3B
gene_biotype: protein_coding
description:
  Glutamate receptor ionotropic, NMDA 3B; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.


ensembl_gene_id: A0A1U8E1M1
symbol: GTF2F2
gene_biotype: protein_coding
description:
  General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity.


ensembl_gene_id: A0A3Q0FH89
symbol: SLC25A47
gene_biotype: protein_coding
description:
  Solute carrier family 25 member 47 isoform X1; Belongs to the mitochondrial carrier (TC 2.A.29) family.


ensembl_gene_id: A0A3Q0FHS5
symbol: LOC106722873
gene_biotype: protein_coding
description:
  Tubulin alpha chain-like; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.


ensembl_gene_id: A0A3Q0FHY5
symbol: LOC102384892
gene_biotype: protein_coding
description:
  Septin-11 isoform X1; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.


ensembl_gene_id: A0A3Q0FI66
symbol: ROR1
gene_biotype: protein_coding
description:
  LOW QUALITY PROTEIN: inactive tyrosine-protein kinase transmembrane receptor ROR1; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily.


ensembl_gene_id: A0A3Q0FI97
symbol: SLC25A29
gene_biotype: protein_coding
description:
  Mitochondrial basic amino acids transporter isoform X2; Belongs to the mitochondrial carrier (TC 2.A.29) family.


ensembl_gene_id: A0A3Q0FIK0
symbol: RPN2
gene_biotype: protein_coding
description:
  Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...]


ensembl_gene_id: A0A3Q0FIN7
symbol: BCAT1
gene_biotype: protein_coding
description:
  Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: A0A3Q0FJ11
symbol: ENOPH1
gene_biotype: protein_coding
description:
  Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).


ensembl_gene_id: A0A3Q0FJ63
symbol: ATG9A
gene_biotype: protein_coding
description:
  Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.


ensembl_gene_id: A0A3Q0FJ70
symbol: SLC2A10
gene_biotype: protein_coding
description:
  Solute carrier family 2, facilitated glucose transporter member 10 isoform X1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.


ensembl_gene_id: A0A3Q0FJM7
symbol: COQ9
gene_biotype: protein_coding
description:
  Ubiquinone biosynthesis protein; Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration.


ensembl_gene_id: A0A3Q0FK70
symbol: DHODH
gene_biotype: protein_coding
description:
  Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.


ensembl_gene_id: A0A3Q0FKA2
symbol: LOC102384144
gene_biotype: protein_coding
description:
  Mitochondrial glutamate carrier 1-like isoform X1; Belongs to the mitochondrial carrier (TC 2.A.29) family.


ensembl_gene_id: A0A3Q0FKL2
symbol: NSUN7
gene_biotype: protein_coding
description:
  Putative methyltransferase NSUN7 isoform X1; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.


ensembl_gene_id: A0A3Q0FKP2
symbol: PTK7
gene_biotype: protein_coding
description:
  Inactive tyrosine-protein kinase 7 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family.


ensembl_gene_id: A0A3Q0FLF8
symbol: MYO1A
gene_biotype: protein_coding
description:
  LOW QUALITY PROTEIN: unconventional myosin-Ia; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.


ensembl_gene_id: A0A3Q0FLS6
symbol: DCAF11
gene_biotype: protein_coding
description:
  DDB1- and CUL4-associated factor 11; May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex; Belongs to the WD repeat LEC14B family.


ensembl_gene_id: A0A3Q0FM51
symbol: SLC44A4
gene_biotype: protein_coding
description:
  LOW QUALITY PROTEIN: choline transporter-like protein 4; Belongs to the CTL (choline transporter-like) family.


ensembl_gene_id: A0A3Q0FM80
symbol: HDAC7
gene_biotype: protein_coding
description:
  Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.


ensembl_gene_id: A0A3Q0FMB6
symbol: LOC102373761
gene_biotype: protein_coding
description:
  Unconventional myosin-X-like; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.


ensembl_gene_id: A0A3Q0FMF2
symbol: WDR4
gene_biotype: protein_coding
description:
  tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4; Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit. Belongs to the WD repeat TRM82 family.


ensembl_gene_id: A0A3Q0FMJ3
symbol: LOC102370745
gene_biotype: protein_coding
description:
  Solute carrier family 2, facilitated glucose transporter member 5 isoform X1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.


ensembl_gene_id: A0A3Q0FMS8
symbol: SRL
gene_biotype: protein_coding
description:
  Sarcalumenin isoform X1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.


ensembl_gene_id: A0A3Q0FMT3
symbol: ADCY9
gene_biotype: protein_coding
description:
  Adenylate cyclase type 9 isoform X1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.


ensembl_gene_id: A0A3Q0FN76
symbol: KIF21B
gene_biotype: protein_coding
description:
  Kinesin-like protein KIF21B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.


ensembl_gene_id: A0A3Q0FN91
symbol: EIF2A
gene_biotype: protein_coding
description:
  Eukaryotic translation initiation factor 2A; Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl- tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.


ensembl_gene_id: A0A3Q0FNK7
symbol: SLC8B1
gene_biotype: protein_coding
description:
  Mitochondrial sodium/calcium exchanger protein; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.


ensembl_gene_id: A0A3Q0FNT5
symbol: ACAT1
gene_biotype: protein_coding
description:
  acetyl-CoA acetyltransferase, mitochondrial; Belongs to the thiolase-like superfamily. Thiolase family.


ensembl_gene_id: A0A3Q0FNZ6
symbol: SBK1
gene_biotype: protein_coding
description:
  Serine/threonine-protein kinase SBK1; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.


ensembl_gene_id: A0A3Q0FPG1
symbol: KCNC4
gene_biotype: protein_coding
description:
  Potassium voltage-gated channel subfamily C member 4 isoform X1; Belongs to the potassium channel family.


ensembl_gene_id: A0A3Q0FPG9
symbol: BCKDHA
gene_biotype: protein_coding
description:
  2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).


ensembl_gene_id: A0A3Q0FPS3
symbol: LOC102371856
gene_biotype: protein_coding
description:
  Low molecular weight neuronal intermediate filament-like; Belongs to the intermediate filament family.


ensembl_gene_id: A0A3Q0FPY9
symbol: LOC102387816
gene_biotype: protein_coding
description:
  Sodium/potassium/calcium exchanger 2-like; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.


ensembl_gene_id: A0A3Q0FQ15
symbol: JPH2
gene_biotype: protein_coding
description:
  Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.


ensembl_gene_id: A0A3Q0FQ75
symbol: SLC2A9
gene_biotype: protein_coding
description:
  Solute carrier family 2, facilitated glucose transporter member 9 isoform X1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.


ensembl_gene_id: A0A3Q0FQM9
symbol: KMT2A
gene_biotype: protein_coding
description:
  Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily.


ensembl_gene_id: A0A3Q0FQN9
symbol: ITPA
gene_biotype: protein_coding
description:
  Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family.


ensembl_gene_id: A0A3Q0FQR4
symbol: LOC102383995
gene_biotype: protein_coding
description:
  Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma-like; Belongs to the PI3/PI4-kinase family.


ensembl_gene_id: A0A3Q0FQU8
symbol: ARPC2
gene_biotype: protein_coding
description:
  Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.


ensembl_gene_id: A0A3Q0FQV3
symbol: ADGRL1
gene_biotype: protein_coding
description:
  Adhesion G protein-coupled receptor L1 isoform X1; Belongs to the G-protein coupled receptor 2 family.


ensembl_gene_id: A0A3Q0FQX7
symbol: LOC102371862
gene_biotype: protein_coding
description:
  LOW QUALITY PROTEIN: adhesion G protein-coupled receptor E3-like; Belongs to the G-protein coupled receptor 2 family.


ensembl_gene_id: A0A3Q0FRL9
symbol: KDSR
gene_biotype: protein_coding
description:
  3-ketodihydrosphingosine reductase isoform X1; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: A0A3Q0FRV0
symbol: ADGRD2
gene_biotype: protein_coding
description:
  LOW QUALITY PROTEIN: adhesion G-protein coupled receptor D2; Belongs to the G-protein coupled receptor 2 family.


ensembl_gene_id: A0A3Q0FS75
symbol: PES1
gene_biotype: protein_coding
description:
  Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.


ensembl_gene_id: A0A3Q0FSD3
symbol: IL16
gene_biotype: protein_coding
description:
  Pro-interleukin-16; Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4.


ensembl_gene_id: A0A3Q0FSF1
symbol: DPYD
gene_biotype: protein_coding
description:
  Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family.


ensembl_gene_id: A0A3Q0FSH7
symbol: CACNA1S
gene_biotype: protein_coding
description:
  Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.


ensembl_gene_id: A0A3Q0FSW4
symbol: TRMT1L
gene_biotype: protein_coding
description:
  TRMT1-like protein isoform X1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.


ensembl_gene_id: A0A3Q0FSY5
symbol: GBA2
gene_biotype: protein_coding
description:
  Non-lysosomal glucosylceramidase; Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide.


ensembl_gene_id: A0A3Q0FT00
symbol: LPCAT3
gene_biotype: protein_coding
description:
  Lysophospholipid acyltransferase 5 isoform X1; Belongs to the membrane-bound acyltransferase family.


ensembl_gene_id: A0A3Q0FT12
symbol: NDUFS2
gene_biotype: protein_coding
description:
  NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial; Belongs to the complex I 49 kDa subunit family.


ensembl_gene_id: A0A3Q0FT51
symbol: LOC102372858
gene_biotype: protein_coding
description:
  Cadherin EGF LAG seven-pass G-type receptor 1 isoform X1; Belongs to the G-protein coupled receptor 2 family.


ensembl_gene_id: A0A3Q0FTF4
symbol: LOC102381531
gene_biotype: protein_coding
description:
  AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]


ensembl_gene_id: A0A3Q0FTM2
symbol: RRP8
gene_biotype: protein_coding
description:
  Ribosomal RNA-processing protein 8; Probable methyltransferase required to silence rDNA. Belongs to the methyltransferase superfamily. RRP8 family.


ensembl_gene_id: A0A3Q0FTS8
symbol: KIF13B
gene_biotype: protein_coding
description:
  Kinesin-like protein KIF13B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.


ensembl_gene_id: A0A3Q0FTV0
symbol: POLL
gene_biotype: protein_coding
description:
  DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.


ensembl_gene_id: A0A3Q0FTZ9
symbol: TUFM
gene_biotype: protein_coding
description:
  Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.


ensembl_gene_id: A0A3Q0FUC6
symbol: PKMYT1
gene_biotype: protein_coding
description:
  Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase; Belongs to the protein kinase superfamily.


ensembl_gene_id: A0A3Q0FUE5
symbol: TP53
gene_biotype: protein_coding
description:
  Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.


ensembl_gene_id: A0A3Q0FUT8
symbol: LOC112548853
gene_biotype: protein_coding
description:
  Uncharacterized protein LOC112548853; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.


ensembl_gene_id: A0A3Q0FUU0
symbol: LOC102379493
gene_biotype: protein_coding
description:
  H-2 class I histocompatibility antigen, Q9 alpha chain-like isoform X1; Belongs to the MHC class I family.


ensembl_gene_id: A0A3Q0FV11
symbol: SLC2A4
gene_biotype: protein_coding
description:
  Solute carrier family 2, facilitated glucose transporter member 4; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.


ensembl_gene_id: A0A3Q0FV42
symbol: MAP2K4
gene_biotype: protein_coding
description:
  Dual specificity mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily.


ensembl_gene_id: A0A3Q0FVA7
symbol: GPN1
gene_biotype: protein_coding
description:
  GPN-loop GTPase; Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.


ensembl_gene_id: A0A3Q0FVD4
symbol: SLC5A6
gene_biotype: protein_coding
description:
  Sodium-dependent multivitamin transporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: A0A3Q0FVF6
symbol: SLC25A38
gene_biotype: protein_coding
description:
  Mitochondrial glycine transporter; Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix. Required during erythropoiesis. Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily.


ensembl_gene_id: A0A3Q0FVJ0
symbol: LOC102385175
gene_biotype: protein_coding
description:
  LOW QUALITY PROTEIN: olfactory receptor 2T7-like; Belongs to the G-protein coupled receptor 1 family.


ensembl_gene_id: A0A3Q0FVT1
symbol: HSPA5
gene_biotype: protein_coding
description:
  LOW QUALITY PROTEIN: endoplasmic reticulum chaperone BiP; Belongs to the heat shock protein 70 family.


ensembl_gene_id: A0A3Q0FVV6
symbol: ADGRD1
gene_biotype: protein_coding
description:
  Adhesion G-protein coupled receptor D1 isoform X1; Belongs to the G-protein coupled receptor 2 family.


ensembl_gene_id: A0A3Q0FWF7
symbol: CLTB
gene_biotype: protein_coding
description:
  Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.


ensembl_gene_id: A0A3Q0FWM6
symbol: PSMD2
gene_biotype: protein_coding
description:
  26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family.


ensembl_gene_id: A0A3Q0FWS7
symbol: SCAI
gene_biotype: protein_coding
description:
  Protein SCAI; Tumor suppressor which functions to suppress MRTFA-induced SRF transcriptional activity.


ensembl_gene_id: A0A3Q0FX45
symbol: LOC102379089
gene_biotype: protein_coding
description:
  Eukaryotic translation initiation factor 3 subunit C; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.


ensembl_gene_id: A0A3Q0FX66
symbol: ALDH18A1
gene_biotype: protein_coding
description:
  Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.


ensembl_gene_id: A0A3Q0FXB7
symbol: SLC25A44
gene_biotype: protein_coding
description:
  Solute carrier family 25 member 44 isoform X1; Belongs to the mitochondrial carrier (TC 2.A.29) family.


ensembl_gene_id: A0A3Q0FXE4
symbol: PRMT1
gene_biotype: protein_coding
description:
  Protein arginine N-methyltransferase 1 isoform X1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.


ensembl_gene_id: A0A3Q0FXE9
symbol: CACNG4
gene_biotype: protein_coding
description:
  Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.


ensembl_gene_id: A0A3Q0FXN2
symbol: MAP2K6
gene_biotype: protein_coding
description:
  Dual specificity mitogen-activated protein kinase kinase 6 isoform X1; Belongs to the protein kinase superfamily.


ensembl_gene_id: A0A3Q0FXP2
symbol: PCSK4
gene_biotype: protein_coding
description:
  LOW QUALITY PROTEIN: proprotein convertase subtilisin/kexin type 4; Belongs to the peptidase S8 family.


ensembl_gene_id: A0A3Q0FY71
symbol: ALDH16A1
gene_biotype: protein_coding
description:
  Aldehyde dehydrogenase family 16 member A1 isoform X1; Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: A0A3Q0FYE0
symbol: RPN1
gene_biotype: protein_coding
description:
  Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...]


ensembl_gene_id: A0A3Q0FYK4
symbol: LOC102386989
gene_biotype: protein_coding
description:
  Vasoactive intestinal polypeptide receptor 1-like; Belongs to the G-protein coupled receptor 2 family.


ensembl_gene_id: A0A3Q0FYU7
symbol: FTSJ3
gene_biotype: protein_coding
description:
  pre-rRNA processing protein FTSJ3; Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation. Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily.


ensembl_gene_id: A0A3Q0FYX6
symbol: ECH1
gene_biotype: protein_coding
description:
  delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial; Belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: A0A3Q0FZ18
symbol: MYO5C
gene_biotype: protein_coding
description:
  Unconventional myosin-Vc; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.


ensembl_gene_id: A0A3Q0FZ40
symbol: LOC102376848
gene_biotype: protein_coding
description:
  Sodium/nucleoside cotransporter isoform X2; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: A0A3Q0FZ85
symbol: AP4E1
gene_biotype: protein_coding
description:
  AP-4 complex subunit epsilon; AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system; Belongs to the adaptor complexes large subunit family.


ensembl_gene_id: A0A3Q0FZJ0
symbol: CDC42BPB
gene_biotype: protein_coding
description:
  Serine/threonine-protein kinase MRCK beta isoform X1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.


ensembl_gene_id: A0A3Q0G0H2
symbol: ST6GALNAC2
gene_biotype: protein_coding
description:
  LOW QUALITY PROTEIN: alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2; Belongs to the glycosyltransferase 29 family.


ensembl_gene_id: A0A3Q0G0I7
symbol: LOC102384407
gene_biotype: protein_coding
description:
  Estradiol 17-beta-dehydrogenase 11; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: A0A3Q0G0J7
symbol: SLC25A19
gene_biotype: protein_coding
description:
  Mitochondrial thiamine pyrophosphate carrier; Belongs to the mitochondrial carrier (TC 2.A.29) family.


ensembl_gene_id: A0A3Q0G0K9
symbol: LOC102370130
gene_biotype: protein_coding
description:
  LOW QUALITY PROTEIN: opsin-5-like; Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.


ensembl_gene_id: A0A3Q0G0Z3
symbol: ST6GALNAC1
gene_biotype: protein_coding
description:
  alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1; Belongs to the glycosyltransferase 29 family.


ensembl_gene_id: A0A3Q0G125
symbol: RHOT1
gene_biotype: protein_coding
description:
  Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family.


ensembl_gene_id: A0A3Q0G1G6
symbol: POLRMT
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the phage and mitochondrial RNA polymerase family.


ensembl_gene_id: A0A3Q0G1H5
symbol: DHX29
gene_biotype: protein_coding
description:
  ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily.


ensembl_gene_id: A0A3Q0G1N7
symbol: TICAM1
gene_biotype: protein_coding
description:
  TIR domain-containing adapter molecule 1; Involved in innate immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of proinflammatory cytokines.


ensembl_gene_id: A0A3Q0G1R9
symbol: LOC102379261
gene_biotype: protein_coding
description:
  Visual pigment-like receptor peropsin; Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.


ensembl_gene_id: A0A3Q0G1S3
symbol: KCNK5
gene_biotype: protein_coding
description:
  Potassium channel subfamily K member 5 isoform X1; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.


ensembl_gene_id: A0A3Q0G1T8
symbol: GLP1R
gene_biotype: protein_coding
description:
  LOW QUALITY PROTEIN: glucagon-like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family.


ensembl_gene_id: A0A3Q0G1X7
symbol: TSHR
gene_biotype: protein_coding
description:
  Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.


ensembl_gene_id: A0A3Q0G2B4
symbol: MED16
gene_biotype: protein_coding
description:
  Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.


ensembl_gene_id: A0A3Q0G2H0
symbol: HMCES
gene_biotype: protein_coding
description:
  Abasic site processing protein HMCES; Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA. The HMCES DNA-protein cross- link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endon [...]


ensembl_gene_id: A0A3Q0G2W6
symbol: EEF1AKMT1
gene_biotype: protein_coding
description:
  EEF1A lysine methyltransferase 1; Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-79'; Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM5 family.


ensembl_gene_id: A0A3Q0G352
symbol: SDHA
gene_biotype: protein_coding
description:
  Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).


ensembl_gene_id: A0A3Q0G398
symbol: KDR
gene_biotype: protein_coding
description:
  Vascular endothelial growth factor receptor 2 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.


ensembl_gene_id: A0A3Q0G3N8
symbol: LOC102384751
gene_biotype: protein_coding
description:
  Parathyroid hormone/parathyroid hormone-related peptide receptor-like; Belongs to the G-protein coupled receptor 2 family.


ensembl_gene_id: A0A3Q0G507
symbol: COPB1
gene_biotype: protein_coding
description:
  Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.


ensembl_gene_id: A0A3Q0G560
symbol: EXOC7
gene_biotype: protein_coding
description:
  Exocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.


ensembl_gene_id: A0A3Q0G592
symbol: SLC25A20
gene_biotype: protein_coding
description:
  Mitochondrial carnitine/acylcarnitine carrier protein; Belongs to the mitochondrial carrier (TC 2.A.29) family.


ensembl_gene_id: A0A3Q0G5N8
symbol: HSD17B3
gene_biotype: protein_coding
description:
  Testosterone 17-beta-dehydrogenase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: A0A3Q0G5V0
symbol: PISD
gene_biotype: protein_coding
description:
  Phosphatidylserine decarboxylase proenzyme, mitochondrial; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine.


ensembl_gene_id: A0A3Q0G5X9
symbol: ELP1
gene_biotype: protein_coding
description:
  Elongator complex protein 1; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. Belongs to the ELP1/IKA1 family.


ensembl_gene_id: A0A3Q0G5Y6
symbol: LOC102372458
gene_biotype: protein_coding
description:
  LOW QUALITY PROTEIN: solute carrier family 2, facilitated glucose transporter member 11-like; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.


ensembl_gene_id: A0A3Q0G674
symbol: SCNN1D
gene_biotype: protein_coding
description:
  Amiloride-sensitive sodium channel subunit delta; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.


ensembl_gene_id: A0A3Q0G6C0
symbol: CRYBG3
gene_biotype: protein_coding
description:
  LOW QUALITY PROTEIN: very large A-kinase anchor protein; Belongs to the beta/gamma-crystallin family.


ensembl_gene_id: A0A3Q0G6J6
symbol: LOC102372710
gene_biotype: protein_coding
description:
  Uncharacterized protein LOC102372710; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.


ensembl_gene_id: A0A3Q0G6R8
symbol: MYO18B
gene_biotype: protein_coding
description:
  LOW QUALITY PROTEIN: unconventional myosin-XVIIIb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.


ensembl_gene_id: A0A3Q0G6Y1
symbol: TFIP11
gene_biotype: protein_coding
description:
  Tuftelin-interacting protein 11; Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Belongs to the TFP11/STIP family.


ensembl_gene_id: A0A3Q0G7A3
symbol: SETD6
gene_biotype: protein_coding
description:
  N-lysine methyltransferase SETD6; Protein-lysine N-methyltransferase. Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SETD6 subfamily.


ensembl_gene_id: A0A3Q0G7R7
symbol: B2M
gene_biotype: protein_coding
description:
  Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.


ensembl_gene_id: A0A3Q0G7X8
symbol: MVK
gene_biotype: protein_coding
description:
  Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.


ensembl_gene_id: A0A3Q0G7Z3
symbol: AVPR1A
gene_biotype: protein_coding
description:
  Vasopressin V1a receptor; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.


ensembl_gene_id: A0A3Q0G8D6
symbol: GPD2
gene_biotype: protein_coding
description:
  Glycerol-3-phosphate dehydrogenase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.


ensembl_gene_id: A0A3Q0G8T7
symbol: COQ3
gene_biotype: protein_coding
description:
  Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.


ensembl_gene_id: A0A3Q0G930
symbol: RSAD1
gene_biotype: protein_coding
description:
  Radical S-adenosyl methionine domain-containing protein; May be a heme chaperone, appears to bind heme. Homologous bacterial proteins do not have oxygen-independent coproporphyrinogen- III oxidase activity. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L- methionine; Belongs to the anaerobic coproporphyrinogen-III oxidase family.


ensembl_gene_id: A0A3Q0G9A3
symbol: LOC102375853
gene_biotype: protein_coding
description:
  Guanylate cyclase soluble subunit beta-2-like; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.


ensembl_gene_id: A0A3Q0G9E1
symbol: LOC102384422
gene_biotype: protein_coding
description:
  Solute carrier family 2, facilitated glucose transporter member 11 isoform X1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.


ensembl_gene_id: A0A3Q0G9G2
symbol: ADGRG6
gene_biotype: protein_coding
description:
  Adhesion G-protein coupled receptor G6 isoform X1; Belongs to the G-protein coupled receptor 2 family.


ensembl_gene_id: A0A3Q0G9H3
symbol: HAT1
gene_biotype: protein_coding
description:
  Histone acetyltransferase type B catalytic subunit; Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG.


ensembl_gene_id: A0A3Q0G9L5
symbol: SEPT7
gene_biotype: protein_coding
description:
  Septin-7 isoform X1; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.


ensembl_gene_id: A0A3Q0G9P4
symbol: NPSR1
gene_biotype: protein_coding
description:
  Neuropeptide S receptor; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.


ensembl_gene_id: A0A3Q0G9V4
symbol: TRPV4
gene_biotype: protein_coding
description:
  LOW QUALITY PROTEIN: transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family.


ensembl_gene_id: A0A3Q0GA52
symbol: TUBG1
gene_biotype: protein_coding
description:
  Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome.


ensembl_gene_id: A0A3Q0GA90
symbol: MED15
gene_biotype: protein_coding
description:
  Mediator of RNA polymerase II transcription subunit 15; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.


ensembl_gene_id: A0A3Q0GAE0
symbol: LOC102371551
gene_biotype: protein_coding
description:
  Sulfate transporter; Sulfate transporter. May play a role in endochondral bone formation; Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.


ensembl_gene_id: A0A3Q0GAR9
symbol: GTF2A2
gene_biotype: protein_coding
description:
  Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family.


ensembl_gene_id: A0A3Q0GAV7
symbol: MRPL22
gene_biotype: protein_coding
description:
  39S ribosomal protein L22, mitochondrial isoform X1; Belongs to the universal ribosomal protein uL22 family.


ensembl_gene_id: A0A3Q0GB41
symbol: LOC102378203
gene_biotype: protein_coding
description:
  Gonadotropin-releasing hormone II receptor-like; Belongs to the G-protein coupled receptor 1 family.


ensembl_gene_id: A0A3Q0GB43
symbol: PHKA2
gene_biotype: protein_coding
description:
  Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. Belongs to the phosphorylase b kinase regulatory chain family.


ensembl_gene_id: A0A3Q0GBG1
symbol: GLRA1
gene_biotype: protein_coding
description:
  Glycine receptor subunit alpha-1 isoform X1; Belongs to the ligand-gated ion channel (TC 1.A.9) family.


ensembl_gene_id: A0A3Q0GBQ4
symbol: LOC102388055
gene_biotype: protein_coding
description:
  Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.


ensembl_gene_id: A0A3Q0GC00
symbol: EIF3A
gene_biotype: protein_coding
description:
  Eukaryotic translation initiation factor 3 subunit A; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.


ensembl_gene_id: A0A3Q0GC56
symbol: KYNU
gene_biotype: protein_coding
description:
  Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.


ensembl_gene_id: A0A3Q0GC92
symbol: SNRPD1
gene_biotype: protein_coding
description:
  Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family.


ensembl_gene_id: A0A3Q0GCA6
symbol: ACTR2
gene_biotype: protein_coding
description:
  Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.


ensembl_gene_id: A0A3Q0GCB1
symbol: NCAPD3
gene_biotype: protein_coding
description:
  Condensin-2 complex subunit D3; Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis.


ensembl_gene_id: A0A3Q0GCC3
symbol: SLC25A1
gene_biotype: protein_coding
description:
  Tricarboxylate transport protein, mitochondrial; Belongs to the mitochondrial carrier (TC 2.A.29) family.


ensembl_gene_id: A0A3Q0GCF9
symbol: GPHN
gene_biotype: protein_coding
description:
  Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.


ensembl_gene_id: A0A3Q0GCK2
symbol: SEPT5
gene_biotype: protein_coding
description:
  Septin-5 isoform X1; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.


ensembl_gene_id: A0A3Q0GCK3
symbol: SLC5A12
gene_biotype: protein_coding
description:
  Sodium-coupled monocarboxylate transporter 2; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: A0A3Q0GCL8
symbol: ADGRL2
gene_biotype: protein_coding
description:
  Adhesion G protein-coupled receptor L2 isoform X1; Belongs to the G-protein coupled receptor 2 family.


ensembl_gene_id: A0A3Q0GCW9
symbol: EIF2B2
gene_biotype: protein_coding
description:
  Translation initiation factor eIF-2B subunit beta; Belongs to the eIF-2B alpha/beta/delta subunits family.


ensembl_gene_id: A0A3Q0GD28
symbol: SRP54
gene_biotype: protein_coding
description:
  Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily.


ensembl_gene_id: A0A3Q0GDI5
symbol: SLC44A3
gene_biotype: protein_coding
description:
  Choline transporter-like protein 3 isoform X1; Belongs to the CTL (choline transporter-like) family.


ensembl_gene_id: A0A3Q0GDS2
symbol: ROCK2
gene_biotype: protein_coding
description:
  Rho-associated protein kinase 2 isoform X1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.


ensembl_gene_id: A0A3Q0GE17
symbol: NAP1L4
gene_biotype: protein_coding
description:
  Nucleosome assembly protein 1-like 4 isoform X1; Belongs to the nucleosome assembly protein (NAP) family.


ensembl_gene_id: A0A3Q0GEB3
symbol: FLT4
gene_biotype: protein_coding
description:
  Vascular endothelial growth factor receptor 3 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.


ensembl_gene_id: A0A3Q0GEY8
symbol: HPGD
gene_biotype: protein_coding
description:
  15-hydroxyprostaglandin dehydrogenase [NAD(+)]; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: A0A3Q0GFA8
symbol: LOC102387428
gene_biotype: protein_coding
description:
  Ethanolaminephosphotransferase 1-like; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: A0A3Q0GFC1
symbol: IARS2
gene_biotype: protein_coding
description:
  isoleucine--tRNA ligase, mitochondrial isoform X1; Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: A0A3Q0GFE2
symbol: LOC102373718
gene_biotype: protein_coding
description:
  Retinol dehydrogenase 12 isoform X1; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: A0A3Q0GFG3
symbol: GLRA3
gene_biotype: protein_coding
description:
  Glycine receptor subunit alpha-3 isoform X1; Belongs to the ligand-gated ion channel (TC 1.A.9) family.


ensembl_gene_id: A0A3Q0GFS3
symbol: TP63
gene_biotype: protein_coding
description:
  Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes.


ensembl_gene_id: A0A3Q0GG01
symbol: LOC102376944
gene_biotype: protein_coding
description:
  Protein HIRA; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family.


ensembl_gene_id: A0A3Q0GG74
symbol: TNK2
gene_biotype: protein_coding
description:
  LOW QUALITY PROTEIN: activated CDC42 kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family.


ensembl_gene_id: A0A3Q0GGC6
symbol: PSMD1
gene_biotype: protein_coding
description:
  26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family.


ensembl_gene_id: A0A3Q0GGC8
symbol: LOC102376455
gene_biotype: protein_coding
description:
  LOW QUALITY PROTEIN: keratin, type I cytoskeletal 15-like; Belongs to the intermediate filament family.


ensembl_gene_id: A0A3Q0GGG2
symbol: CDC6
gene_biotype: protein_coding
description:
  Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.


ensembl_gene_id: A0A3Q0GGG5
symbol: RTEL1
gene_biotype: protein_coding
description:
  Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by  [...]


ensembl_gene_id: A0A3Q0GGK2
symbol: MYO1E
gene_biotype: protein_coding
description:
  Unconventional myosin-Ie isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.


ensembl_gene_id: A0A3Q0GGL2
symbol: DNM1L
gene_biotype: protein_coding
description:
  Dynamin-1-like protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.


ensembl_gene_id: A0A3Q0GHC9
symbol: GABRG1
gene_biotype: protein_coding
description:
  LOW QUALITY PROTEIN: gamma-aminobutyric acid receptor subunit gamma-1; Belongs to the ligand-gated ion channel (TC 1.A.9) family.


ensembl_gene_id: A0A3Q0GI02
symbol: LOC102377482
gene_biotype: protein_coding
description:
  Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]


ensembl_gene_id: A0A3Q0GIA4
symbol: KCNQ1
gene_biotype: protein_coding
description:
  Potassium voltage-gated channel subfamily KQT member 1 isoform X1; Belongs to the potassium channel family.


ensembl_gene_id: A0A3Q0GJ41
symbol: QTRT1
gene_biotype: protein_coding
description:
  Queuine tRNA-ribosyltransferase catalytic subunit 1; Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, formi [...]


ensembl_gene_id: A0A3Q0GJ66
symbol: SLC44A1
gene_biotype: protein_coding
description:
  Choline transporter-like protein 1 isoform X1; Belongs to the CTL (choline transporter-like) family.


ensembl_gene_id: A0A3Q0GJ98
symbol: DNMT1
gene_biotype: protein_coding
description:
  DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.


ensembl_gene_id: A0A3Q0GJB8
symbol: LOC102382142
gene_biotype: protein_coding
description:
  Retinol dehydrogenase 8-like isoform X1; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: A0A3Q0GJD7
symbol: LPL
gene_biotype: protein_coding
description:
  Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.


ensembl_gene_id: A0A3Q0GJS6
symbol: CARM1
gene_biotype: protein_coding
description:
  Histone-arginine methyltransferase CARM1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.


ensembl_gene_id: A0A3Q0GJT1
symbol: DNM2
gene_biotype: protein_coding
description:
  Dynamin-2 isoform X1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.


ensembl_gene_id: A0A3Q0GJX9
symbol: CACNA1A
gene_biotype: protein_coding
description:
  Voltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents.


ensembl_gene_id: A0A3Q0GK41
symbol: PRMT9
gene_biotype: protein_coding
description:
  Protein arginine N-methyltransferase 9 isoform X1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.


ensembl_gene_id: A0A3Q0GK85
symbol: ATP6V0C
gene_biotype: protein_coding
description:
  V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.


ensembl_gene_id: A0A3Q0GKY4
symbol: LOC102385272
gene_biotype: protein_coding
description:
  Dual specificity protein phosphatase 22-A-like; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.


ensembl_gene_id: A0A3Q0GLF2
symbol: DUSP19
gene_biotype: protein_coding
description:
  Dual specificity protein phosphatase 19; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.


ensembl_gene_id: A0A3Q0GLH3
symbol: PRIM2
gene_biotype: protein_coding
description:
  DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands.


ensembl_gene_id: A0A3Q0GLI9
symbol: PPIP5K2
gene_biotype: protein_coding
description:
  Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates  [...]


ensembl_gene_id: A0A3Q0GLP4
symbol: ALDH1L2
gene_biotype: protein_coding
description:
  10-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily.


ensembl_gene_id: A0A3Q0GLR9
symbol: LOC102369473
gene_biotype: protein_coding
description:
  Unconventional myosin-XV-like; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.


ensembl_gene_id: A0A3Q0GLX9
symbol: LSM1
gene_biotype: protein_coding
description:
  U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs.


ensembl_gene_id: A0A3Q0GM32
symbol: PTPA
gene_biotype: protein_coding
description:
  Serine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.


ensembl_gene_id: A0A3Q0GM48
symbol: DNM1
gene_biotype: protein_coding
description:
  Dynamin-1 isoform X1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.


ensembl_gene_id: A0A3Q0GMD5
symbol: SEPT12
gene_biotype: protein_coding
description:
  Septin-12; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.


ensembl_gene_id: A0A3Q0GMF8
symbol: LOC102380821
gene_biotype: protein_coding
description:
  Kinesin-like protein KIF28P; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.


ensembl_gene_id: A0A3Q0GMH2
symbol: LOC102385029
gene_biotype: protein_coding
description:
  ADP-ribosylation factor-like protein 8B isoform X1; Belongs to the small GTPase superfamily. Arf family.


ensembl_gene_id: A0A3Q0GN60
symbol: NFIX
gene_biotype: protein_coding
description:
  Nuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.


ensembl_gene_id: A0A3Q0GN66
symbol: RNASEH2A
gene_biotype: protein_coding
description:
  Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.


ensembl_gene_id: A0A3Q0GN75
symbol: EIF3G
gene_biotype: protein_coding
description:
  Eukaryotic translation initiation factor 3 subunit G; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. This subunit can bind 18S rRNA.


ensembl_gene_id: A0A3Q0GN89
symbol: TRMT1
gene_biotype: protein_coding
description:
  tRNA (Guanine(26)-N(2))-dimethyltransferase isoform X1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.


ensembl_gene_id: A0A3Q0GND8
symbol: PRKD3
gene_biotype: protein_coding
description:
  Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.


ensembl_gene_id: A0A3Q0GNM7
symbol: ESR1
gene_biotype: protein_coding
description:
  Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.


ensembl_gene_id: A0A3Q0GNN1
symbol: ECSIT
gene_biotype: protein_coding
description:
  LOW QUALITY PROTEIN: evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial.


ensembl_gene_id: A0A3Q0GNR6
symbol: NUBP2
gene_biotype: protein_coding
description:
  Cytosolic Fe-S cluster assembly factor NUBP2; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily.


ensembl_gene_id: A0A3Q0GPE2
symbol: LOC102387010
gene_biotype: protein_coding
description:
  S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.


ensembl_gene_id: A0A3Q0GPU0
symbol: PIK3C2A
gene_biotype: protein_coding
description:
  LOW QUALITY PROTEIN: phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha; Belongs to the PI3/PI4-kinase family.


ensembl_gene_id: A0A3Q0GPZ5
symbol: SLC8A1
gene_biotype: protein_coding
description:
  Sodium/calcium exchanger 1 isoform X1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.


ensembl_gene_id: A0A3Q0GQ91
symbol: UBA7
gene_biotype: protein_coding
description:
  Ubiquitin-like modifier-activating enzyme 7 isoform X1; Belongs to the ubiquitin-activating E1 family.


ensembl_gene_id: A0A3Q0GQF0
symbol: SLC5A10
gene_biotype: protein_coding
description:
  Sodium/glucose cotransporter 5 isoform X1; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: A0A3Q0GR93
symbol: PRTFDC1
gene_biotype: protein_coding
description:
  Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.


ensembl_gene_id: A0A3Q0GR94
symbol: NSUN4
gene_biotype: protein_coding
description:
  5-methylcytosine rRNA methyltransferase NSUN4 isoform X1; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.


ensembl_gene_id: A0A3Q0GRU5
symbol: IPPK
gene_biotype: protein_coding
description:
  Inositol-pentakisphosphate 2-kinase; Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate).


ensembl_gene_id: A0A3Q0GRZ9
symbol: LOC102381808
gene_biotype: protein_coding
description:
  Kinesin-like protein KIF26B isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.


ensembl_gene_id: A0A3Q0GS33
symbol: ADCYAP1R1
gene_biotype: protein_coding
description:
  Pituitary adenylate cyclase-activating polypeptide type I receptor; Belongs to the G-protein coupled receptor 2 family.


ensembl_gene_id: A0A3Q0GS95
symbol: MB
gene_biotype: protein_coding
description:
  Myoglobin; Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.


ensembl_gene_id: A0A3Q0GSA9
symbol: CNR1
gene_biotype: protein_coding
description:
  Cannabinoid receptor; Involved in cannabinoid-induced CNS effects. Belongs to the G-protein coupled receptor 1 family.


ensembl_gene_id: A0A3Q0GSB9
symbol: RNGTT
gene_biotype: protein_coding
description:
  Polynucleotide 5'-triphosphatase; Bifunctional mRNA-capping enzyme exhibiting RNA 5'- triphosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the gmp moiety of GTP to the 5'-diphosphate terminus.


ensembl_gene_id: A0A3Q0GSC8
symbol: ELOVL1
gene_biotype: protein_coding
description:
  Elongation of very long chain fatty acids protein 1; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that  [...]


ensembl_gene_id: A0A3Q0GSE5
symbol: MED14
gene_biotype: protein_coding
description:
  Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.


ensembl_gene_id: A0A3Q0GSU3
symbol: TERT
gene_biotype: protein_coding
description:
  Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.


ensembl_gene_id: A0A3Q0GSY7
symbol: RFT1
gene_biotype: protein_coding
description:
  Protein RFT1 homolog; May be involved in N-linked oligosaccharide assembly. Belongs to the RFT1 family.


ensembl_gene_id: A0A3Q0GTA7
symbol: ST3GAL3
gene_biotype: protein_coding
description:
  CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X1; Belongs to the glycosyltransferase 29 family.


ensembl_gene_id: A0A3Q0GTB3
symbol: KCNC1
gene_biotype: protein_coding
description:
  Potassium voltage-gated channel subfamily C member 1 isoform X4; Belongs to the potassium channel family.


ensembl_gene_id: A0A3Q0GTJ8
symbol: MYO1D
gene_biotype: protein_coding
description:
  Unconventional myosin-Id; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.


ensembl_gene_id: A0A3Q0GU79
symbol: MED6
gene_biotype: protein_coding
description:
  Mediator of RNA polymerase II transcription subunit 6; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.


ensembl_gene_id: A0A3Q0GU87
symbol: REV1
gene_biotype: protein_coding
description:
  DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.


ensembl_gene_id: A0A3Q0GUF6
symbol: DLAT
gene_biotype: protein_coding
description:
  Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


ensembl_gene_id: A0A3Q0GUK6
symbol: KCND2
gene_biotype: protein_coding
description:
  Potassium voltage-gated channel subfamily D member 2 isoform X2; Belongs to the potassium channel family.


ensembl_gene_id: A0A3Q0GUL4
symbol: SDHD
gene_biotype: protein_coding
description:
  Succinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family.


ensembl_gene_id: A0A3Q0GUN8
symbol: SLC26A4
gene_biotype: protein_coding
description:
  Pendrin; Sodium-independent transporter of chloride and iodide. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.


ensembl_gene_id: A0A3Q0GUR1
symbol: KCNG3
gene_biotype: protein_coding
description:
  LOW QUALITY PROTEIN: potassium voltage-gated channel subfamily G member 3; Belongs to the potassium channel family.


ensembl_gene_id: A0A3Q0GUR5
symbol: CACNA1E
gene_biotype: protein_coding
description:
  Voltage-dependent R-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents.


ensembl_gene_id: A0A3Q0GUR7
symbol: SLC26A3
gene_biotype: protein_coding
description:
  Chloride anion exchanger; Chloride/bicarbonate exchanger. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.


ensembl_gene_id: A0A3Q0GVD1
symbol: GAR1
gene_biotype: protein_coding
description:
  H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine (psi) residues may serve to stabilize the conformation of rRNAs.


ensembl_gene_id: A0A3Q0GVS8
symbol: SLC25A24
gene_biotype: protein_coding
description:
  Calcium-binding mitochondrial carrier protein SCaMC-1; Belongs to the mitochondrial carrier (TC 2.A.29) family.


ensembl_gene_id: A0A3Q0GW56
symbol: TIMM44
gene_biotype: protein_coding
description:
  Mitochondrial import inner membrane translocase subunit TIM44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the Tim44 family.


ensembl_gene_id: A0A3Q0GW92
symbol: SCP2
gene_biotype: protein_coding
description:
  Non-specific lipid-transfer protein isoform X1; Belongs to the thiolase-like superfamily. Thiolase family.


ensembl_gene_id: A0A3Q0GWC0
symbol: CPT2
gene_biotype: protein_coding
description:
  Carnitine O-palmitoyltransferase 2, mitochondrial isoform X1; Belongs to the carnitine/choline acetyltransferase family.


ensembl_gene_id: A0A3Q0GWP3
symbol: ACKR2
gene_biotype: protein_coding
description:
  LOW QUALITY PROTEIN: atypical chemokine receptor 2; Belongs to the G-protein coupled receptor 1 family.


ensembl_gene_id: A0A3Q0GWX0
symbol: TRPC1
gene_biotype: protein_coding
description:
  Short transient receptor potential channel 1 isoform X1; Belongs to the transient receptor (TC 1.A.4) family.


ensembl_gene_id: A0A3Q0GWX6
symbol: MED8
gene_biotype: protein_coding
description:
  Mediator of RNA polymerase II transcription subunit 8; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.


ensembl_gene_id: A0A3Q0GX41
symbol: ST8SIA1
gene_biotype: protein_coding
description:
  alpha-N-acetylneuraminide alpha-2,8-sialyltransferase; Belongs to the glycosyltransferase 29 family.


ensembl_gene_id: A0A3Q0GX49
symbol: EARS2
gene_biotype: protein_coding
description:
  Probable glutamate--tRNA ligase, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: A0A3Q0GX60
symbol: CIT
gene_biotype: protein_coding
description:
  Citron Rho-interacting kinase; Plays a role in cytokinesis. Displays serine/threonine protein kinase activity; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.


ensembl_gene_id: A0A3Q0GXK7
symbol: KATNAL1
gene_biotype: protein_coding
description:
  Katanin p60 ATPase-containing subunit A-like 1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily. A-like 1 sub-subfamily.


ensembl_gene_id: A0A3Q0GXK8
symbol: FLT1
gene_biotype: protein_coding
description:
  Vascular endothelial growth factor receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.


ensembl_gene_id: A0A3Q0GXP6
symbol: DHRS7
gene_biotype: protein_coding
description:
  Dehydrogenase/reductase SDR family member 7; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: A0A3Q0GXY0
symbol: RIOK1
gene_biotype: protein_coding
description:
  Serine/threonine-protein kinase RIO1; Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.


ensembl_gene_id: A0A3Q0GYC6
symbol: DUS4L
gene_biotype: protein_coding
description:
  tRNA-dihydrouridine synthase; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs; Belongs to the dus family.


ensembl_gene_id: A0A3Q0GYG5
symbol: SLC25A13
gene_biotype: protein_coding
description:
  Calcium-binding mitochondrial carrier protein Aralar2 isoform X1; Belongs to the mitochondrial carrier (TC 2.A.29) family.


ensembl_gene_id: A0A3Q0GYT2
symbol: SUCLG2
gene_biotype: protein_coding
description:
  Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.


ensembl_gene_id: A0A3Q0GYV2
symbol: SLC25A26
gene_biotype: protein_coding
description:
  S-adenosylmethionine mitochondrial carrier protein; Belongs to the mitochondrial carrier (TC 2.A.29) family.


ensembl_gene_id: A0A3Q0GZ38
symbol: PTPN3
gene_biotype: protein_coding
description:
  Tyrosine-protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily.


ensembl_gene_id: A0A3Q0GZ44
symbol: MOCOS
gene_biotype: protein_coding
description:
  Molybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.


ensembl_gene_id: A0A3Q0GZ66
symbol: KIF1A
gene_biotype: protein_coding
description:
  LOW QUALITY PROTEIN: kinesin-like protein KIF1A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.


ensembl_gene_id: A0A3Q0GZE1
symbol: LOC102371226
gene_biotype: protein_coding
description:
  LOW QUALITY PROTEIN: myosin-10-like; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.


ensembl_gene_id: A0A3Q0GZI7
symbol: PRMT8
gene_biotype: protein_coding
description:
  Protein arginine N-methyltransferase 8; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.


ensembl_gene_id: A0A3Q0GZK2
symbol: ST6GAL1
gene_biotype: protein_coding
description:
  LOW QUALITY PROTEIN: beta-galactoside alpha-2,6-sialyltransferase 1; Belongs to the glycosyltransferase 29 family.


ensembl_gene_id: A0A3Q0GZS7
symbol: NAE1
gene_biotype: protein_coding
description:
  NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.


ensembl_gene_id: A0A3Q0H088
symbol: LOC102388529
gene_biotype: protein_coding
description:
  Mitochondrial uncoupling protein 2 isoform X1; Belongs to the mitochondrial carrier (TC 2.A.29) family.


ensembl_gene_id: A0A3Q0H094
symbol: MYH15
gene_biotype: protein_coding
description:
  LOW QUALITY PROTEIN: myosin-15; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.


ensembl_gene_id: A0A3Q0H0D4
symbol: KIF7
gene_biotype: protein_coding
description:
  Kinesin-like protein KIF7 isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.


ensembl_gene_id: A0A3Q0H0F5
symbol: KIF21A
gene_biotype: protein_coding
description:
  LOW QUALITY PROTEIN: kinesin-like protein KIF21A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.


ensembl_gene_id: A0A3Q0H0K5
symbol: UBA2
gene_biotype: protein_coding
description:
  SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.


ensembl_gene_id: A0A3Q0H0M2
symbol: LOC102384210
gene_biotype: protein_coding
description:
  Potassium voltage-gated channel subfamily KQT member 1-like isoform X1; Belongs to the potassium channel family.


ensembl_gene_id: A0A3Q0H0R5
symbol: LOC102370650
gene_biotype: protein_coding
description:
  Gamma-aminobutyric acid receptor subunit beta-2-like; Belongs to the ligand-gated ion channel (TC 1.A.9) family.


ensembl_gene_id: A0A3Q0H0R8
symbol: GPR17
gene_biotype: protein_coding
description:
  Uracil nucleotide/cysteinyl leukotriene receptor; Belongs to the G-protein coupled receptor 1 family.


ensembl_gene_id: A0A3Q0H0V5
symbol: LOC102368372
gene_biotype: protein_coding
description:
  Leucine carboxyl methyltransferase 1; Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha- leucine ester residues; Belongs to the methyltransferase superfamily. LCMT family.


ensembl_gene_id: A0A3Q0H0W3
symbol: SLC5A11
gene_biotype: protein_coding
description:
  Sodium/myo-inositol cotransporter 2 isoform X1; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: A0A3Q0H163
symbol: CHM
gene_biotype: protein_coding
description:
  Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.


ensembl_gene_id: A0A3Q0H184
symbol: SLC2A13
gene_biotype: protein_coding
description:
  Proton myo-inositol cotransporter; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.


ensembl_gene_id: A0A3Q0H1D4
symbol: RPLP2
gene_biotype: protein_coding
description:
  60S acidic ribosomal protein P2 isoform X1; Belongs to the eukaryotic ribosomal protein P1/P2 family.


ensembl_gene_id: A0A3Q0H1E9
symbol: KIF13A
gene_biotype: protein_coding
description:
  LOW QUALITY PROTEIN: kinesin-like protein KIF13A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.


ensembl_gene_id: A0A3Q0H1M0
symbol: ENTPD4
gene_biotype: protein_coding
description:
  Ectonucleoside triphosphate diphosphohydrolase 4 isoform X1; Belongs to the GDA1/CD39 NTPase family.


ensembl_gene_id: A0A3Q0H1N7
symbol: GPC1
gene_biotype: protein_coding
description:
  Glypican-1 isoform X1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.


ensembl_gene_id: A0A3Q0H1S2
symbol: DHRS11
gene_biotype: protein_coding
description:
  Dehydrogenase/reductase SDR family member 11 isoform X1; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: A0A3Q0H1T8
symbol: ADGRB1
gene_biotype: protein_coding
description:
  LOW QUALITY PROTEIN: adhesion G protein-coupled receptor B1; Belongs to the G-protein coupled receptor 2 family.


ensembl_gene_id: A0A3Q0H1Y8
symbol: HSD17B2
gene_biotype: protein_coding
description:
  Estradiol 17-beta-dehydrogenase 2 isoform X1; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: A0A3Q0H201
symbol: SDR42E1
gene_biotype: protein_coding
description:
  Short-chain dehydrogenase/reductase family 42E member 1 isoform X1; Belongs to the 3-beta-HSD family.


ensembl_gene_id: A0A3Q0H204
symbol: GCSH
gene_biotype: protein_coding
description:
  Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family.


ensembl_gene_id: A0A3Q0H224
symbol: SLC25A42
gene_biotype: protein_coding
description:
  Mitochondrial coenzyme A transporter SLC25A42; Belongs to the mitochondrial carrier (TC 2.A.29) family.


ensembl_gene_id: A0A3Q0H227
symbol: LSM4
gene_biotype: protein_coding
description:
  U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA.


ensembl_gene_id: A0A3Q0H265
symbol: KCNS3
gene_biotype: protein_coding
description:
  LOW QUALITY PROTEIN: potassium voltage-gated channel subfamily S member 3; Belongs to the potassium channel family.


ensembl_gene_id: A0A3Q0H2C5
symbol: LOC102384784
gene_biotype: protein_coding
description:
  Gamma-aminobutyric acid receptor subunit gamma-4; Belongs to the ligand-gated ion channel (TC 1.A.9) family.


ensembl_gene_id: A0A3Q0H2J5
symbol: TXNDC5
gene_biotype: protein_coding
description:
  Thioredoxin domain-containing protein 5 isoform X2; Belongs to the protein disulfide isomerase family.


ensembl_gene_id: A0A3Q0H2K6
symbol: BLOC1S5
gene_biotype: protein_coding
description:
  Biogenesis of lysosome-related organelles complex 1 subunit 5; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO).


ensembl_gene_id: A0A3Q0H2P2
symbol: MYO10
gene_biotype: protein_coding
description:
  LOW QUALITY PROTEIN: unconventional myosin-X; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.


ensembl_gene_id: A0A3Q0H2P4
symbol: NTF3
gene_biotype: protein_coding
description:
  Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family.


ensembl_gene_id: A0A3Q0H2P5
symbol: SEPT3
gene_biotype: protein_coding
description:
  Neuronal-specific septin-3 isoform X1; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.


ensembl_gene_id: A0A3Q0H326
symbol: UGDH
gene_biotype: protein_coding
description:
  UDP-glucose 6-dehydrogenase; Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate. Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.


ensembl_gene_id: A0A3Q0H373
symbol: LOC102372656
gene_biotype: protein_coding
description:
  LOW QUALITY PROTEIN: ATPase family AAA domain-containing protein 1-B-like; Belongs to the AAA ATPase family.


ensembl_gene_id: A0A3Q0H3G2
symbol: G6PD
gene_biotype: protein_coding
description:
  Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.


ensembl_gene_id: A0A3Q0H3N8
symbol: ST3GAL6
gene_biotype: protein_coding
description:
  Type 2 lactosamine alpha-2,3-sialyltransferase isoform X1; Belongs to the glycosyltransferase 29 family.


ensembl_gene_id: A0A3Q0H487
symbol: MCM7
gene_biotype: protein_coding
description:
  DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]


ensembl_gene_id: A0A3Q0H4G0
symbol: DYNC1LI2
gene_biotype: protein_coding
description:
  Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.


ensembl_gene_id: A0A3Q0H4I5
symbol: CACNA1B
gene_biotype: protein_coding
description:
  Voltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents.


ensembl_gene_id: A0A3Q0H4M8
symbol: DPM2
gene_biotype: protein_coding
description:
  Dolichol phosphate-mannose biosynthesis regulatory protein; Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization. Belongs to the DPM2 family.


ensembl_gene_id: A0A3Q0H4N0
symbol: KCNK2
gene_biotype: protein_coding
description:
  Potassium channel subfamily K member 2; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.


ensembl_gene_id: A0A3Q0H4S8
symbol: SLC2A6
gene_biotype: protein_coding
description:
  LOW QUALITY PROTEIN: solute carrier family 2, facilitated glucose transporter member 6; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.


ensembl_gene_id: A0A3Q0H5D1
symbol: BDH1
gene_biotype: protein_coding
description:
  D-beta-hydroxybutyrate dehydrogenase, mitochondrial; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: A0A3Q0H5G6
symbol: SLC25A33
gene_biotype: protein_coding
description:
  Solute carrier family 25 member 33 isoform X1; Belongs to the mitochondrial carrier (TC 2.A.29) family.


ensembl_gene_id: A0A3Q0H5H1
symbol: LOC102384482
gene_biotype: protein_coding
description:
  Glypican-5-like; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.


ensembl_gene_id: A0A3Q0H5T9
symbol: WARS2
gene_biotype: protein_coding
description:
  tryptophan--tRNA ligase, mitochondrial isoform X1; Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: A0A3Q0H5V1
symbol: AK1
gene_biotype: protein_coding
description:
  Adenylate kinase isoenzyme 1; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.


ensembl_gene_id: A0A3Q0H631
symbol: ST3GAL5
gene_biotype: protein_coding
description:
  Lactosylceramide alpha-2,3-sialyltransferase isoform X1; Belongs to the glycosyltransferase 29 family.


ensembl_gene_id: A0A3Q0H7A4
symbol: TP73
gene_biotype: protein_coding
description:
  Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.


ensembl_gene_id: A0A3Q0H7J0
symbol: SUCLA2
gene_biotype: protein_coding
description:
  Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.


ensembl_gene_id: A0A3Q0H7Q0
symbol: LIAS
gene_biotype: protein_coding
description:
  Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.


ensembl_gene_id: A0A3Q0H7U0
symbol: CLUH
gene_biotype: protein_coding
description:
  Clustered mitochondria protein homolog; mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria. Specifically binds mRNAs of nuclear- encoded mitochondrial proteins in the cytoplasm and regulates transport or translation of these transcripts close to mitochondria, playing a role in mitochondrial biogenesis; Belongs to the CLU family.


ensembl_gene_id: A0A3Q0H9Q1
symbol: LOC102381171
gene_biotype: protein_coding
description:
  LOW QUALITY PROTEIN: uncharacterized serine/threonine-protein kinase SBK3-like; Belongs to the protein kinase superfamily.


ensembl_gene_id: A0A3Q0HA04
symbol: TRRAP
gene_biotype: protein_coding
description:
  LOW QUALITY PROTEIN: transformation/transcription domain-associated protein; Belongs to the PI3/PI4-kinase family.


ensembl_gene_id: A0A3Q0HA15
symbol: LOC102371919
gene_biotype: protein_coding
description:
  D-beta-hydroxybutyrate dehydrogenase, mitochondrial-like; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: A0A3Q0HA50
symbol: PRKACB
gene_biotype: protein_coding
description:
  cAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily.


ensembl_gene_id: A0A3Q0HAN4
symbol: UGT8
gene_biotype: protein_coding
description:
  2-hydroxyacylsphingosine 1-beta-galactosyltransferase isoform X1; Belongs to the UDP-glycosyltransferase family.


ensembl_gene_id: A0A3Q0HBA7
symbol: NCAPD2
gene_biotype: protein_coding
description:
  Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.


ensembl_gene_id: A0A3Q0HBF2
symbol: MRTO4
gene_biotype: protein_coding
description:
  Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.


ensembl_gene_id: A0A3Q0HBH4
symbol: PHGDH
gene_biotype: protein_coding
description:
  D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: A0A3Q0HBN5
symbol: LOC102374086
gene_biotype: protein_coding
description:
  LOW QUALITY PROTEIN: plasma membrane calcium-transporting ATPase 3; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.


ensembl_gene_id: A0A3Q0HBQ6
symbol: PORCN
gene_biotype: protein_coding
description:
  Protein-serine O-palmitoleoyltransferase porcupine isoform X1; Belongs to the membrane-bound acyltransferase family.


ensembl_gene_id: A0A3Q0HBZ2
symbol: DNMT3B
gene_biotype: protein_coding
description:
  DNA (Cytosine-5)-methyltransferase 3B; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.


ensembl_gene_id: A0A3Q0HC08
symbol: DUSP15
gene_biotype: protein_coding
description:
  Dual specificity protein phosphatase 15 isoform X1; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.


ensembl_gene_id: A0A3Q0HC55
symbol: KIF1B
gene_biotype: protein_coding
description:
  Kinesin-like protein KIF1B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.


ensembl_gene_id: A0A3Q0HC87
symbol: GABRD
gene_biotype: protein_coding
description:
  Gamma-aminobutyric acid receptor subunit delta; Belongs to the ligand-gated ion channel (TC 1.A.9) family.


ensembl_gene_id: A0A3Q0HCC1
symbol: TRMT2A
gene_biotype: protein_coding
description:
  tRNA (Uracil-5-)-methyltransferase homolog A isoform X1; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.


ensembl_gene_id: A0A3Q0HCC9
symbol: LOC112551680
gene_biotype: protein_coding
description:
  LOW QUALITY PROTEIN: olfactory receptor-like protein COR9; Belongs to the G-protein coupled receptor 1 family.


ensembl_gene_id: A0A3Q0HD05
symbol: SPDL1
gene_biotype: protein_coding
description:
  Protein Spindly; Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex; Belongs to the Spindly family.


ensembl_gene_id: A0A3Q0HD58
symbol: FLAD1
gene_biotype: protein_coding
description:
  FAD synthase; Catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme. In the C-terminal section; belongs to the PAPS reductase family. FAD1 subfamily.


ensembl_gene_id: A0A3Q0HD62
symbol: LOC102368462
gene_biotype: protein_coding
description:
  Vascular endothelial growth factor receptor kdr-like; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.


ensembl_gene_id: A0A3Q0HDE6
symbol: LOC102367915
gene_biotype: protein_coding
description:
  LOW QUALITY PROTEIN: desmoglein-1-like; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.


ensembl_gene_id: A0A3Q0HDG3
symbol: AP3M1
gene_biotype: protein_coding
description:
  LOW QUALITY PROTEIN: AP-3 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.


ensembl_gene_id: A0A3Q0HDH5
symbol: MAF1
gene_biotype: protein_coding
description:
  Repressor of RNA polymerase III transcription MAF1; Element of the TORC1 signaling pathway that acts as a mediator of diverse signals and that represses RNA polymerase III transcription. Inhibits the de novo assembly of TFIIIB onto DNA. Belongs to the MAF1 family.


ensembl_gene_id: A0A3Q0HDZ3
symbol: SLC2A3
gene_biotype: protein_coding
description:
  Solute carrier family 2, facilitated glucose transporter member 3; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.


ensembl_gene_id: A0A3Q0HED2
symbol: LOC102372244
gene_biotype: protein_coding
description:
  C5a anaphylatoxin chemotactic receptor 1 isoform X1; Belongs to the G-protein coupled receptor 1 family.


ensembl_gene_id: A0A3Q0HEE0
symbol: PTK2
gene_biotype: protein_coding
description:
  Focal adhesion kinase 1 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family.


ensembl_gene_id: A0A3Q0HEI1
symbol: MYO18A
gene_biotype: protein_coding
description:
  Unconventional myosin-XVIIIa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.


ensembl_gene_id: A0A3Q0HEK1
symbol: SUPT6H
gene_biotype: protein_coding
description:
  Transcription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family.


ensembl_gene_id: A0A3Q0HER2
symbol: NAXE
gene_biotype: protein_coding
description:
  NAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.


ensembl_gene_id: A0A3Q0HEW6
symbol: GART
gene_biotype: protein_coding
description:
  Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family.  In the central section; belongs to the AIR synthase family.


ensembl_gene_id: A0A3Q0HF10
symbol: FBLN1
gene_biotype: protein_coding
description:
  Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes.


ensembl_gene_id: A0A3Q0HF46
symbol: LOC102372182
gene_biotype: protein_coding
description:
  Transient receptor potential cation channel subfamily V member 1 isoform X1; Belongs to the transient receptor (TC 1.A.4) family.


ensembl_gene_id: A0A3Q0HGI7
symbol: POLR3GL
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase III subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.


ensembl_gene_id: A0A3Q0HGV8
symbol: CTBP1
gene_biotype: protein_coding
description:
  C-terminal-binding protein 1 isoform X1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: A0A3Q0HHM9
symbol: CENPE
gene_biotype: protein_coding
description:
  LOW QUALITY PROTEIN: centromere-associated protein E; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.


ensembl_gene_id: A0A3Q0HHN7
symbol: SLC25A36
gene_biotype: protein_coding
description:
  Solute carrier family 25 member 36 isoform X1; Belongs to the mitochondrial carrier (TC 2.A.29) family.


ensembl_gene_id: A0A3Q0HHQ9
symbol: NSUN5
gene_biotype: protein_coding
description:
  Probable 28S rRNA (Cytosine-C(5))-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.


ensembl_gene_id: A0A3Q0HHR0
symbol: BOP1
gene_biotype: protein_coding
description:
  Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.


ensembl_gene_id: A0A3Q0HHX3
symbol: CRABP2
gene_biotype: protein_coding
description:
  Cellular retinoic acid-binding protein 2; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.


ensembl_gene_id: A0A3Q0HHX6
symbol: SELENOI
gene_biotype: protein_coding
description:
  Ethanolaminephosphotransferase 1 isoform X1; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: A0A3Q0HI02
symbol: TIMM50
gene_biotype: protein_coding
description:
  Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.


ensembl_gene_id: A0A3Q0HIB6
symbol: LOC112551958
gene_biotype: protein_coding
description:
  LOW QUALITY PROTEIN: mas-related G-protein coupled receptor member H-like; Belongs to the G-protein coupled receptor 1 family.


ensembl_gene_id: A0A3Q0HIZ0
symbol: LOC102377700
gene_biotype: protein_coding
description:
  Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B-like; Belongs to the transient receptor (TC 1.A.4) family.


ensembl_gene_id: A0A3Q0HJL8
symbol: EIF6
gene_biotype: protein_coding
description:
  Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.


ensembl_gene_id: A0A3Q0HJR3
symbol: CDC42BPA
gene_biotype: protein_coding
description:
  Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.


ensembl_gene_id: A0A3Q0HJV4
symbol: ARL2
gene_biotype: protein_coding
description:
  ADP-ribosylation factor-like protein 2 isoform X1; Belongs to the small GTPase superfamily. Arf family.


ensembl_gene_id: A0A3Q0HK10
symbol: GFM1
gene_biotype: protein_coding
description:
  Elongation factor G, mitochondrial; Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. Does not mediate the disassembly of ribosomes from messenger RNA at the termination of mito [...]


ensembl_gene_id: A0A3Q0HK18
symbol: LOC102381524
gene_biotype: protein_coding
description:
  Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.


ensembl_gene_id: A0A3Q0HK22
symbol: NSUN3
gene_biotype: protein_coding
description:
  tRNA (Cytosine(34)-C(5))-methyltransferase, mitochondrial; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.


ensembl_gene_id: A0A3Q0HK63
symbol: ATG7
gene_biotype: protein_coding
description:
  Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]


ensembl_gene_id: A0A3Q0HKJ6
symbol: SEPT10
gene_biotype: protein_coding
description:
  Septin-10; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.


ensembl_gene_id: A0A3Q0HKP0
symbol: LOC102385137
gene_biotype: protein_coding
description:
  Protein farnesyltransferase subunit beta; Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.


ensembl_gene_id: A0A3Q0HKU3
symbol: VBP1
gene_biotype: protein_coding
description:
  Prefoldin subunit 3; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit alpha family.


ensembl_gene_id: A0A3Q0HKX5
symbol: PGM3
gene_biotype: protein_coding
description:
  Phosphoacetylglucosamine mutase; Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, a sugar nucleotide critical to multiple glycosylation pathways including protein N- and O- glycosylation; Belongs to the phosphohexose mutase family.


ensembl_gene_id: A0A3Q0HL46
symbol: LOC102388548
gene_biotype: protein_coding
description:
  alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2-like isoform X1; Belongs to the glycosyltransferase 29 family.


ensembl_gene_id: A0A3Q0HLI9
symbol: ENTPD7
gene_biotype: protein_coding
description:
  Ectonucleoside triphosphate diphosphohydrolase 7 isoform X1; Belongs to the GDA1/CD39 NTPase family.


ensembl_gene_id: A0A3Q0HLN2
symbol: SEPT4
gene_biotype: protein_coding
description:
  Septin-4 isoform X1; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.


ensembl_gene_id: A0A3Q0HLR2
symbol: ZMPSTE24
gene_biotype: protein_coding
description:
  CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family.


ensembl_gene_id: A0A3Q0HLX9
symbol: KIF19
gene_biotype: protein_coding
description:
  LOW QUALITY PROTEIN: kinesin-like protein KIF19; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.


ensembl_gene_id: A0A3Q0HNJ7
symbol: ORC4
gene_biotype: protein_coding
description:
  Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family.


ensembl_gene_id: A0A3Q0HPS1
symbol: SSRP1
gene_biotype: protein_coding
description:
  FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]


ensembl_gene_id: A0A3Q0HQ71
symbol: GPR142
gene_biotype: protein_coding
description:
  LOW QUALITY PROTEIN: probable G-protein coupled receptor 142; Belongs to the G-protein coupled receptor 1 family.


ensembl_gene_id: A0A3Q0HQJ9
symbol: ATAT1
gene_biotype: protein_coding
description:
  Alpha-tubulin N-acetyltransferase 1; Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dyn [...]


ensembl_gene_id: Q8HG38
symbol: ND6
gene_biotype: protein_coding
description:
  NADH-ubiquinone oxidoreductase chain 6; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.


ensembl_gene_id: Q8HG39
symbol: ND5
gene_biotype: protein_coding
description:
  NADH-ubiquinone oxidoreductase chain 5; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.


ensembl_gene_id: Q8HG40
symbol: ND4
gene_biotype: protein_coding
description:
  NADH-ubiquinone oxidoreductase chain 4; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.


ensembl_gene_id: Q8HG42
symbol: ND3
gene_biotype: protein_coding
description:
  NADH-ubiquinone oxidoreductase chain 3; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.


ensembl_gene_id: Q8HG43
symbol: COX3
gene_biotype: protein_coding
description:
  Cytochrome c oxidase subunit 3; Subunits I, II and III form the functional core of the enzyme complex.


ensembl_gene_id: Q8HG46
symbol: COX2
gene_biotype: protein_coding
description:
  Cytochrome c oxidase subunit 2; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1.


ensembl_gene_id: Q8HG47
symbol: COX1
gene_biotype: protein_coding
description:
  Cytochrome c oxidase subunit 1; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.


ensembl_gene_id: Q8HG48
symbol: ND2
gene_biotype: protein_coding
description:
  NADH-ubiquinone oxidoreductase chain 2; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.


