# geneInfo

ensembl_gene_id: S7S_00005
symbol: dnaA
gene_biotype: protein_coding
description:
  Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.


ensembl_gene_id: S7S_00010
symbol: S7S_00010
gene_biotype: protein_coding
description:
  DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of  [...]


ensembl_gene_id: S7S_00015
symbol: recF
gene_biotype: protein_coding
description:
  Recombination protein F; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family.


ensembl_gene_id: S7S_00020
symbol: gyrB
gene_biotype: protein_coding
description:
  DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.


ensembl_gene_id: S7S_00025
symbol: S7S_00025
gene_biotype: protein_coding
description:
  Two component transcriptional regulator; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: S7S_00040
symbol: S7S_00040
gene_biotype: protein_coding
description:
  Histidinol-phosphate phosphatase family domain-containing protein; COG0241 Histidinol phosphatase and related phosphatases.


ensembl_gene_id: S7S_00085
symbol: S7S_00085
gene_biotype: protein_coding
description:
  HMGL-like protein; COG0119 Isopropylmalate/homocitrate/citramalate synthases; Belongs to the alpha-IPM synthase/homocitrate synthase family.


ensembl_gene_id: S7S_00095
symbol: S7S_00095
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1075 Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold.


ensembl_gene_id: S7S_00130
symbol: trkA
gene_biotype: protein_coding
description:
  Potassium transporter peripheral membrane component; COG0569 K+ transport systems, NAD-binding component.


ensembl_gene_id: S7S_00135
symbol: S7S_00135
gene_biotype: protein_coding
description:
  tRNA and rRNA cytosine-C5-methylase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.


ensembl_gene_id: S7S_00140
symbol: fmt
gene_biotype: protein_coding
description:
  methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.


ensembl_gene_id: S7S_00145
symbol: def
gene_biotype: protein_coding
description:
  Peptide deformylase 1; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.


ensembl_gene_id: S7S_00155
symbol: S7S_00155
gene_biotype: protein_coding
description:
  Peptide deformylase; COG0758 Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake.


ensembl_gene_id: S7S_00160
symbol: tsaC
gene_biotype: protein_coding
description:
  Sua5/YciO/YrdC/YwlC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.


ensembl_gene_id: S7S_00165
symbol: hemF
gene_biotype: protein_coding
description:
  Coproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX.


ensembl_gene_id: S7S_00170
symbol: aroE
gene_biotype: protein_coding
description:
  Shikimate dehydrogenase 1; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).


ensembl_gene_id: S7S_00195
symbol: S7S_00195
gene_biotype: protein_coding
description:
  Addiction module antidote protein; COG3609 Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain.


ensembl_gene_id: S7S_00200
symbol: S7S_00200
gene_biotype: protein_coding
description:
  Toxin, ParE-ParD toxin-antitoxin system; COG3668 Plasmid stabilization system protein; Belongs to the RelE toxin family.


ensembl_gene_id: S7S_00230
symbol: S7S_00230
gene_biotype: protein_coding
description:
  Transmembrane PepSY domain-containing protein; COG3182 Uncharacterized iron-regulated membrane protein.


ensembl_gene_id: S7S_00255
symbol: recG
gene_biotype: protein_coding
description:
  ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily.


ensembl_gene_id: S7S_00260
symbol: S7S_00260
gene_biotype: protein_coding
description:
  Hydrogen peroxide-inducible gene activator OxyR; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: S7S_00275
symbol: S7S_00275
gene_biotype: protein_coding
description:
  GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.


ensembl_gene_id: S7S_00280
symbol: rpoZ
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.


ensembl_gene_id: S7S_00325
symbol: lspA
gene_biotype: protein_coding
description:
  Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.


ensembl_gene_id: S7S_00340
symbol: S7S_00340
gene_biotype: protein_coding
description:
  Winged helix family two component transcriptional regulator; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: S7S_00365
symbol: S7S_00365
gene_biotype: protein_coding
description:
  Phage integrase family site specific recombinase; COG0582 Integrase; Belongs to the 'phage' integrase family.


ensembl_gene_id: S7S_00375
symbol: rph
gene_biotype: protein_coding
description:
  Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.


ensembl_gene_id: S7S_00380
symbol: pyrE
gene_biotype: protein_coding
description:
  Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).


ensembl_gene_id: S7S_00390
symbol: slmA
gene_biotype: protein_coding
description:
  Division inhibitor protein; Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.


ensembl_gene_id: S7S_00395
symbol: argB
gene_biotype: protein_coding
description:
  Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.


ensembl_gene_id: S7S_00405
symbol: dut
gene_biotype: protein_coding
description:
  Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.


ensembl_gene_id: S7S_00410
symbol: S7S_00410
gene_biotype: protein_coding
description:
  Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.


ensembl_gene_id: S7S_00440
symbol: modB
gene_biotype: protein_coding
description:
  Molybdate ABC transporter permease protein; Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: S7S_00445
symbol: S7S_00445
gene_biotype: protein_coding
description:
  Molybdenum ABC transporter periplasmic molybdate-binding protein; COG0725 ABC-type molybdate transport system, periplasmic component.


ensembl_gene_id: S7S_00465
symbol: S7S_00465
gene_biotype: protein_coding
description:
  Type II secretion system protein; COG4964 Flp pilus assembly protein, secretin CpaC; Belongs to the bacterial secretin family.


ensembl_gene_id: S7S_00480
symbol: S7S_00480
gene_biotype: protein_coding
description:
  Type II secretion system protein F domain-containing protein; COG4965 Flp pilus assembly protein TadB.


ensembl_gene_id: S7S_00485
symbol: S7S_00485
gene_biotype: protein_coding
description:
  Type II secretion system protein F domain-containing protein; COG2064 Flp pilus assembly protein TadC.


ensembl_gene_id: S7S_00515
symbol: mutM
gene_biotype: protein_coding
description:
  formamidopyrimidine-DNA glycosylase 2; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.


ensembl_gene_id: S7S_00540
symbol: coaD
gene_biotype: protein_coding
description:
  Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.


ensembl_gene_id: S7S_00590
symbol: S7S_00590
gene_biotype: protein_coding
description:
  COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs.


ensembl_gene_id: S7S_00595
symbol: S7S_00595
gene_biotype: protein_coding
description:
  hydroxymethylglutaryl-CoA reductase, degradative; COG1257 Hydroxymethylglutaryl-CoA reductase; Belongs to the HMG-CoA reductase family.


ensembl_gene_id: S7S_00605
symbol: S7S_00605
gene_biotype: protein_coding
description:
  CoA-transferase family III; COG1804 Predicted acyl-CoA transferases/carnitine dehydratase; Belongs to the CoA-transferase III family.


ensembl_gene_id: S7S_00610
symbol: S7S_00610
gene_biotype: protein_coding
description:
  TRAP-T family transporter, DctP (Periplasmic binding) subunit; COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component.


ensembl_gene_id: S7S_00625
symbol: S7S_00625
gene_biotype: protein_coding
description:
  TRAP dicarboxylate transporter subunit DctQ; COG3090 TRAP-type C4-dicarboxylate transport system, small permease component.


ensembl_gene_id: S7S_00630
symbol: S7S_00630
gene_biotype: protein_coding
description:
  TRAP-T family protein transporter, DctM (12 TMs) subunit; COG1593 TRAP-type C4-dicarboxylate transport system, large permease component.


ensembl_gene_id: S7S_00650
symbol: S7S_00650
gene_biotype: protein_coding
description:
  Methyltransferase; Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle; Belongs to the methyltransferase superfamily. RsmD family.


ensembl_gene_id: S7S_00665
symbol: ftsY
gene_biotype: protein_coding
description:
  Cell division transporter substrate-binding protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.


ensembl_gene_id: S7S_00670
symbol: ftsE
gene_biotype: protein_coding
description:
  Cell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division.


ensembl_gene_id: S7S_00675
symbol: S7S_00675
gene_biotype: protein_coding
description:
  Cell division protein FtsX; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.


ensembl_gene_id: S7S_00680
symbol: rpoH
gene_biotype: protein_coding
description:
  RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.


ensembl_gene_id: S7S_00695
symbol: thiG
gene_biotype: protein_coding
description:
  Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.


ensembl_gene_id: S7S_00720
symbol: S7S_00720
gene_biotype: protein_coding
description:
  Peptide-aspartate beta-dioxygenase; COG3555 Aspartyl/asparaginyl beta-hydroxylase and related dioxygenases.


ensembl_gene_id: S7S_00740
symbol: S7S_00740
gene_biotype: protein_coding
description:
  COG0685 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.


ensembl_gene_id: S7S_00745
symbol: ahcY
gene_biotype: protein_coding
description:
  S-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.


ensembl_gene_id: S7S_00750
symbol: metK
gene_biotype: protein_coding
description:
  S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.


ensembl_gene_id: S7S_00765
symbol: tpm
gene_biotype: protein_coding
description:
  Thiopurine S-methyltransferase; COG0500 SAM-dependent methyltransferases; Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.


ensembl_gene_id: S7S_00845
symbol: S7S_00845
gene_biotype: protein_coding
description:
  Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.


ensembl_gene_id: S7S_00850
symbol: S7S_00850
gene_biotype: protein_coding
description:
  COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.


ensembl_gene_id: S7S_00860
symbol: S7S_00860
gene_biotype: protein_coding
description:
  Fructose-bisphosphate aldolase, class II, Calvin cycle subtype; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.


ensembl_gene_id: S7S_00905
symbol: S7S_00905
gene_biotype: protein_coding
description:
  COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: S7S_00915
symbol: S7S_00915
gene_biotype: protein_coding
description:
  Fumarylacetoacetate hydrolase family protein; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).


ensembl_gene_id: S7S_00925
symbol: rpiA
gene_biotype: protein_coding
description:
  Ribose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.


ensembl_gene_id: S7S_00930
symbol: ilvA
gene_biotype: protein_coding
description:
  Threonine ammonia-lyase, biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.


ensembl_gene_id: S7S_00940
symbol: S7S_00940
gene_biotype: protein_coding
description:
  COG0212 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.


ensembl_gene_id: S7S_00945
symbol: S7S_00945
gene_biotype: protein_coding
description:
  Hypothetical protein; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.


ensembl_gene_id: S7S_00965
symbol: S7S_00965
gene_biotype: protein_coding
description:
  Oxygenase; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.


ensembl_gene_id: S7S_00980
symbol: dapD
gene_biotype: protein_coding
description:
  Putative tetrahydrodipicolinate N-succinyltransferase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.


ensembl_gene_id: S7S_00990
symbol: S7S_00990
gene_biotype: protein_coding
description:
  Iron ABC transporter substrate-binding protein; COG1840 ABC-type Fe3+ transport system, periplasmic component.


ensembl_gene_id: S7S_01020
symbol: gcvT
gene_biotype: protein_coding
description:
  Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine.


ensembl_gene_id: S7S_01025
symbol: gcvH
gene_biotype: protein_coding
description:
  Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.


ensembl_gene_id: S7S_01030
symbol: gcvPA
gene_biotype: protein_coding
description:
  Glycine dehydrogenase subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.


ensembl_gene_id: S7S_01035
symbol: gcvPB
gene_biotype: protein_coding
description:
  Glycine dehydrogenase subunit 2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily.


ensembl_gene_id: S7S_01100
symbol: rppH
gene_biotype: protein_coding
description:
  RNA pyrophosphohydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily.


ensembl_gene_id: S7S_01105
symbol: S7S_01105
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate-protein phosphotransferase PtsP; COG3605 Signal transduction protein containing GAF and PtsI domains; Belongs to the PEP-utilizing enzyme family.


ensembl_gene_id: S7S_01125
symbol: lgt
gene_biotype: protein_coding
description:
  Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.


ensembl_gene_id: S7S_01130
symbol: thyA
gene_biotype: protein_coding
description:
  Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.


ensembl_gene_id: S7S_01135
symbol: S7S_01135
gene_biotype: protein_coding
description:
  Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.


ensembl_gene_id: S7S_01180
symbol: S7S_01180
gene_biotype: protein_coding
description:
  Hypothetical protein; COG3609 Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain.


ensembl_gene_id: S7S_01185
symbol: S7S_01185
gene_biotype: protein_coding
description:
  Aminoglycoside resistance protein; Mediates bacterial resistance to the antibiotics streptomycin and spectomycin.


ensembl_gene_id: S7S_01190
symbol: S7S_01190
gene_biotype: protein_coding
description:
  Membrane-associated protein in eicosanoid and glutathione metabolism (mapeg); COG5331 Uncharacterized protein conserved in bacteria.


ensembl_gene_id: S7S_01195
symbol: S7S_01195
gene_biotype: protein_coding
description:
  Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family.


ensembl_gene_id: S7S_01210
symbol: xerC
gene_biotype: protein_coding
description:
  Integrase/recombinase XerC; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.


ensembl_gene_id: S7S_01220
symbol: dapF
gene_biotype: protein_coding
description:
  Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.


ensembl_gene_id: S7S_01255
symbol: lysA
gene_biotype: protein_coding
description:
  Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.


ensembl_gene_id: S7S_01285
symbol: S7S_01285
gene_biotype: protein_coding
description:
  Two-component system sensor protein, alginate biosynthesis; COG2972 Predicted signal transduction protein with a C-terminal ATPase domain.


ensembl_gene_id: S7S_01340
symbol: pckA
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.


ensembl_gene_id: S7S_01345
symbol: hslO
gene_biotype: protein_coding
description:
  33 kDa chaperonin; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.


ensembl_gene_id: S7S_01350
symbol: S7S_01350
gene_biotype: protein_coding
description:
  S4 domain-containing protein; COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog); Belongs to the HSP15 family.


ensembl_gene_id: S7S_01360
symbol: nudE
gene_biotype: protein_coding
description:
  Adenosine nucleotide hydrolase NudE; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes.


ensembl_gene_id: S7S_01365
symbol: cysQ
gene_biotype: protein_coding
description:
  3'(2'),5'-bisphosphate nucleotidase; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family.


ensembl_gene_id: S7S_01395
symbol: S7S_01395
gene_biotype: protein_coding
description:
  Drug resistance MFS transporter, drug:H+ antiporter-1; COG0477 Permeases of the major facilitator superfamily.


ensembl_gene_id: S7S_01410
symbol: S7S_01410
gene_biotype: protein_coding
description:
  Oxidative damage protection protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.


ensembl_gene_id: S7S_01440
symbol: hisH
gene_biotype: protein_coding
description:
  Glutamine amidotransferase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.


ensembl_gene_id: S7S_01445
symbol: hisA
gene_biotype: protein_coding
description:
  Imidazole-4-carboxamide isomerase; COG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase.


ensembl_gene_id: S7S_01455
symbol: hisF
gene_biotype: protein_coding
description:
  Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.


ensembl_gene_id: S7S_01485
symbol: S7S_01485
gene_biotype: protein_coding
description:
  Glutaredoxin; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.


ensembl_gene_id: S7S_01490
symbol: secB
gene_biotype: protein_coding
description:
  Protein-export protein secB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.


ensembl_gene_id: S7S_01495
symbol: trmL
gene_biotype: protein_coding
description:
  RNA methyltransferase; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.


ensembl_gene_id: S7S_01515
symbol: S7S_01515
gene_biotype: protein_coding
description:
  alpha-L-glutamate ligase; COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase).


ensembl_gene_id: S7S_01545
symbol: S7S_01545
gene_biotype: protein_coding
description:
  COG0482 Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain.


ensembl_gene_id: S7S_01550
symbol: S7S_01550
gene_biotype: protein_coding
description:
  COG0425 Predicted redox protein, regulator of disulfide bond formation; Belongs to the sulfur carrier protein TusA family.


ensembl_gene_id: S7S_01570
symbol: ntrC
gene_biotype: protein_coding
description:
  Fis family nitrogen metabolism transcriptional regulator NtrC; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.


ensembl_gene_id: S7S_01580
symbol: S7S_01580
gene_biotype: protein_coding
description:
  Proline iminopeptidase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); Belongs to the peptidase S33 family.


ensembl_gene_id: S7S_01585
symbol: dtd
gene_biotype: protein_coding
description:
  D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family.


ensembl_gene_id: S7S_01605
symbol: tatC
gene_biotype: protein_coding
description:
  Sec-independent periplasmic protein translocator TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.


ensembl_gene_id: S7S_01610
symbol: tatB
gene_biotype: protein_coding
description:
  Twin arginine-targeting protein translocase TatB; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.


ensembl_gene_id: S7S_01615
symbol: tatA
gene_biotype: protein_coding
description:
  Sec-independent protein translocase protein tatA/E; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.


ensembl_gene_id: S7S_01635
symbol: ubiE
gene_biotype: protein_coding
description:
  Ubiquinone/menaquinone biosynthesis methyltransferase ubiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2).


ensembl_gene_id: S7S_01645
symbol: hslU
gene_biotype: protein_coding
description:
  ATP-dependent protease ATP-binding subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.


ensembl_gene_id: S7S_01650
symbol: hslV
gene_biotype: protein_coding
description:
  ATP-dependent protease subunit HslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.


ensembl_gene_id: S7S_01665
symbol: priA
gene_biotype: protein_coding
description:
  Replication restart DNA helicase PriA; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.


ensembl_gene_id: S7S_01710
symbol: aroK
gene_biotype: protein_coding
description:
  Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.


ensembl_gene_id: S7S_01715
symbol: aroB
gene_biotype: protein_coding
description:
  3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).


ensembl_gene_id: S7S_01735
symbol: hemE
gene_biotype: protein_coding
description:
  Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.


ensembl_gene_id: S7S_01760
symbol: S7S_01760
gene_biotype: protein_coding
description:
  Pterin-4-alpha-carbinolamine dehydratase superfamily protein; COG2154 Pterin-4a-carbinolamine dehydratase.


ensembl_gene_id: S7S_01775
symbol: S7S_01775
gene_biotype: protein_coding
description:
  2-phosphosulfolactate phosphatase subfamily protein; COG2045 Phosphosulfolactate phosphohydrolase and related enzymes; Belongs to the ComB family.


ensembl_gene_id: S7S_01790
symbol: bioB
gene_biotype: protein_coding
description:
  Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.


ensembl_gene_id: S7S_01795
symbol: bioF
gene_biotype: protein_coding
description:
  8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.


ensembl_gene_id: S7S_01800
symbol: bioH
gene_biotype: protein_coding
description:
  Biotin biosynthesis protein bioH; The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.


ensembl_gene_id: S7S_01805
symbol: bioC
gene_biotype: protein_coding
description:
  Biotin biosynthesis protein BioC; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.


ensembl_gene_id: S7S_01810
symbol: bioD
gene_biotype: protein_coding
description:
  Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.


ensembl_gene_id: S7S_01840
symbol: S7S_01840
gene_biotype: protein_coding
description:
  methylated-DNA--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.


ensembl_gene_id: S7S_01865
symbol: S7S_01865
gene_biotype: protein_coding
description:
  COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: S7S_01915
symbol: S7S_01915
gene_biotype: protein_coding
description:
  TonB-dependent outer-membrane transporter; COG4771 Outer membrane receptor for ferrienterochelin and colicins.


ensembl_gene_id: S7S_01930
symbol: leuA
gene_biotype: protein_coding
description:
  2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.


ensembl_gene_id: S7S_01940
symbol: secD
gene_biotype: protein_coding
description:
  Bifunctional preprotein translocase subunit SecD/SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily.


ensembl_gene_id: S7S_01975
symbol: S7S_01975
gene_biotype: protein_coding
description:
  COG1062 Zn-dependent alcohol dehydrogenases, class III; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.


ensembl_gene_id: S7S_01990
symbol: moaA
gene_biotype: protein_coding
description:
  Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.


ensembl_gene_id: S7S_02005
symbol: ubiD
gene_biotype: protein_coding
description:
  3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.


ensembl_gene_id: S7S_02010
symbol: S7S_02010
gene_biotype: protein_coding
description:
  Tat (twin-arginine translocation) pathway signal sequence domain-containing protein; COG3211 Predicted phosphatase.


ensembl_gene_id: S7S_02020
symbol: rho
gene_biotype: protein_coding
description:
  Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.


ensembl_gene_id: S7S_02035
symbol: ppk
gene_biotype: protein_coding
description:
  Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family.


ensembl_gene_id: S7S_02050
symbol: S7S_02050
gene_biotype: protein_coding
description:
  Glyoxalase/bleomycin resistance protein/dioxygenase; COG3565 Predicted dioxygenase of extradiol dioxygenase family.


ensembl_gene_id: S7S_02055
symbol: greB
gene_biotype: protein_coding
description:
  Transcription elongation factor GreB; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.


ensembl_gene_id: S7S_02065
symbol: S7S_02065
gene_biotype: protein_coding
description:
  Isoprenoid biosynthesis protein; Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate; Belongs to the peptidase C56 family.


ensembl_gene_id: S7S_02100
symbol: dsbB
gene_biotype: protein_coding
description:
  Disulfide bond formation protein DsbB; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family.


ensembl_gene_id: S7S_02110
symbol: gshA
gene_biotype: protein_coding
description:
  Glutamate--cysteine ligase; COG2918 Gamma-glutamylcysteine synthetase; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.


ensembl_gene_id: S7S_02130
symbol: ompR
gene_biotype: protein_coding
description:
  COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: S7S_02160
symbol: S7S_02160
gene_biotype: protein_coding
description:
  ATPase, histidine kinase-, DNA gyrase B-, and HSP90-like domain-containing protein; COG0642 Signal transduction histidine kinase.


ensembl_gene_id: S7S_02175
symbol: hemC
gene_biotype: protein_coding
description:
  Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.


ensembl_gene_id: S7S_02180
symbol: S7S_02180
gene_biotype: protein_coding
description:
  uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.


ensembl_gene_id: S7S_02195
symbol: hemH
gene_biotype: protein_coding
description:
  Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.


ensembl_gene_id: S7S_02200
symbol: S7S_02200
gene_biotype: protein_coding
description:
  (Fe-S)-binding protein; COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases.


ensembl_gene_id: S7S_02220
symbol: argA
gene_biotype: protein_coding
description:
  N-acetylglutamate synthase; COG0548 Acetylglutamate kinase; Belongs to the acetyltransferase family. ArgA subfamily.


ensembl_gene_id: S7S_02235
symbol: S7S_02235
gene_biotype: protein_coding
description:
  Type II secretion system protein; COG2804 Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB.


ensembl_gene_id: S7S_02240
symbol: glnE
gene_biotype: protein_coding
description:
  Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...]


ensembl_gene_id: S7S_02245
symbol: ilvE
gene_biotype: protein_coding
description:
  Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: S7S_02265
symbol: S7S_02265
gene_biotype: protein_coding
description:
  Lipopolysaccharide core heptose(I) kinase RfaP; Catalyzes the phosphorylation of heptose(I) of the outer membrane lipopolysaccharide core; Belongs to the protein kinase superfamily. KdkA/rfaP family.


ensembl_gene_id: S7S_02310
symbol: lpxL
gene_biotype: protein_coding
description:
  Lipid A biosynthesis lauroyl acyltransferase; Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A).


ensembl_gene_id: S7S_02315
symbol: hldE
gene_biotype: protein_coding
description:
  Bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family.


ensembl_gene_id: S7S_02330
symbol: S7S_02330
gene_biotype: protein_coding
description:
  3-deoxy-D-manno-octulosonic-acid transferase subfamily protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.


ensembl_gene_id: S7S_02340
symbol: thiC
gene_biotype: protein_coding
description:
  Phosphomethylpyrimidine synthase ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.


ensembl_gene_id: S7S_02345
symbol: S7S_02345
gene_biotype: protein_coding
description:
  ADP-ribose pyrophosphatase; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes.


ensembl_gene_id: S7S_02355
symbol: cpdA
gene_biotype: protein_coding
description:
  Icc protein; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.


ensembl_gene_id: S7S_02365
symbol: parE
gene_biotype: protein_coding
description:
  DNA topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily.


ensembl_gene_id: S7S_02370
symbol: parC
gene_biotype: protein_coding
description:
  DNA topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.


ensembl_gene_id: S7S_02385
symbol: S7S_02385
gene_biotype: protein_coding
description:
  COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; Belongs to the pseudouridine synthase RsuA family.


ensembl_gene_id: S7S_02405
symbol: S7S_02405
gene_biotype: protein_coding
description:
  Putative short chain dehydrogenase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: S7S_02415
symbol: srkA
gene_biotype: protein_coding
description:
  Serine/threonine protein kinase; A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.


ensembl_gene_id: S7S_02445
symbol: S7S_02445
gene_biotype: protein_coding
description:
  Cytochrome c oxidase, cbb3-type subunit III; C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.


ensembl_gene_id: S7S_02460
symbol: S7S_02460
gene_biotype: protein_coding
description:
  COG3278 Cbb3-type cytochrome oxidase, subunit 1; Belongs to the heme-copper respiratory oxidase family.


ensembl_gene_id: S7S_02485
symbol: S7S_02485
gene_biotype: protein_coding
description:
  Penicillin-binding protein; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).


ensembl_gene_id: S7S_02495
symbol: S7S_02495
gene_biotype: protein_coding
description:
  Antitoxin of toxin-antitoxin stability system; Antitoxin component of a type II toxin-antitoxin (TA) system.


ensembl_gene_id: S7S_02520
symbol: S7S_02520
gene_biotype: protein_coding
description:
  PKD domain-containing protein; COG3979 Uncharacterized protein contain chitin-binding domain type 3.


ensembl_gene_id: S7S_02595
symbol: S7S_02595
gene_biotype: protein_coding
description:
  Von Willebrand factor type A; COG4245 Uncharacterized protein encoded in toxicity protection region of plasmid R478, contains von Willebrand factor (vWF) domain.


ensembl_gene_id: S7S_02605
symbol: vapC
gene_biotype: protein_coding
description:
  Plasmid maintenance protein; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family.


ensembl_gene_id: S7S_02620
symbol: thiE
gene_biotype: protein_coding
description:
  Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.


ensembl_gene_id: S7S_02635
symbol: argC
gene_biotype: protein_coding
description:
  N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.


ensembl_gene_id: S7S_02650
symbol: erpA
gene_biotype: protein_coding
description:
  Iron--sulfur cluster insertion protein erpA; Required for insertion of 4Fe-4S clusters for at least IspG.


ensembl_gene_id: S7S_02665
symbol: anmK
gene_biotype: protein_coding
description:
  anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family.


ensembl_gene_id: S7S_02675
symbol: tyrS
gene_biotype: protein_coding
description:
  tyrosine-tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.


ensembl_gene_id: S7S_02720
symbol: S7S_02720
gene_biotype: protein_coding
description:
  ABC transporter permease; COG0559 Branched-chain amino acid ABC-type transport system, permease components; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: S7S_02725
symbol: S7S_02725
gene_biotype: protein_coding
description:
  ABC transporter permease; COG4177 ABC-type branched-chain amino acid transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: S7S_02730
symbol: S7S_02730
gene_biotype: protein_coding
description:
  Urea ABC transporter permease; COG4177 ABC-type branched-chain amino acid transport system, permease component.


ensembl_gene_id: S7S_02740
symbol: S7S_02740
gene_biotype: protein_coding
description:
  Urea ABC transporter ATP-binding protein UrtE; COG0410 ABC-type branched-chain amino acid transport systems, ATPase component.


ensembl_gene_id: S7S_02755
symbol: birA
gene_biotype: protein_coding
description:
  biotin-[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.


ensembl_gene_id: S7S_02760
symbol: coaX
gene_biotype: protein_coding
description:
  Type III pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.


ensembl_gene_id: S7S_02770
symbol: tuf
gene_biotype: protein_coding
description:
  Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.


ensembl_gene_id: S7S_02775
symbol: secE
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61-gamma family.


ensembl_gene_id: S7S_02780
symbol: nusG
gene_biotype: protein_coding
description:
  Transcription antitermination protein NusG; Participates in transcription elongation, termination and antitermination.


ensembl_gene_id: S7S_02785
symbol: rplK
gene_biotype: protein_coding
description:
  50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.


ensembl_gene_id: S7S_02790
symbol: rplA
gene_biotype: protein_coding
description:
  50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.


ensembl_gene_id: S7S_02795
symbol: rplJ
gene_biotype: protein_coding
description:
  50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.


ensembl_gene_id: S7S_02800
symbol: rplL
gene_biotype: protein_coding
description:
  50S ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family.


ensembl_gene_id: S7S_02805
symbol: rpoB
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: S7S_02815
symbol: rpsL
gene_biotype: protein_coding
description:
  30S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.


ensembl_gene_id: S7S_02820
symbol: rpsG
gene_biotype: protein_coding
description:
  30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.


ensembl_gene_id: S7S_02825
symbol: fusA
gene_biotype: protein_coding
description:
  Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...]


ensembl_gene_id: S7S_02835
symbol: rpsJ
gene_biotype: protein_coding
description:
  30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.


ensembl_gene_id: S7S_02840
symbol: rplC
gene_biotype: protein_coding
description:
  50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.


ensembl_gene_id: S7S_02850
symbol: rplW
gene_biotype: protein_coding
description:
  50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.


ensembl_gene_id: S7S_02855
symbol: rplB
gene_biotype: protein_coding
description:
  50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.


ensembl_gene_id: S7S_02860
symbol: rpsS
gene_biotype: protein_coding
description:
  30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.


ensembl_gene_id: S7S_02865
symbol: rplV
gene_biotype: protein_coding
description:
  50S ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.


ensembl_gene_id: S7S_02870
symbol: rpsC
gene_biotype: protein_coding
description:
  30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.


ensembl_gene_id: S7S_02875
symbol: rplP
gene_biotype: protein_coding
description:
  50S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.


ensembl_gene_id: S7S_02885
symbol: rpsQ
gene_biotype: protein_coding
description:
  30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.


ensembl_gene_id: S7S_02890
symbol: rplN
gene_biotype: protein_coding
description:
  50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.


ensembl_gene_id: S7S_02895
symbol: rplX
gene_biotype: protein_coding
description:
  50S ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.


ensembl_gene_id: S7S_02900
symbol: rplE
gene_biotype: protein_coding
description:
  50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.


ensembl_gene_id: S7S_02905
symbol: rpsN
gene_biotype: protein_coding
description:
  30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family.


ensembl_gene_id: S7S_02910
symbol: rpsH
gene_biotype: protein_coding
description:
  30S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.


ensembl_gene_id: S7S_02915
symbol: rplF
gene_biotype: protein_coding
description:
  50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.


ensembl_gene_id: S7S_02920
symbol: rplR
gene_biotype: protein_coding
description:
  50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.


ensembl_gene_id: S7S_02925
symbol: rpsE
gene_biotype: protein_coding
description:
  30S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.


ensembl_gene_id: S7S_02935
symbol: rplO
gene_biotype: protein_coding
description:
  50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.


ensembl_gene_id: S7S_02940
symbol: secY
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.


ensembl_gene_id: S7S_02950
symbol: rpsM
gene_biotype: protein_coding
description:
  30S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family.


ensembl_gene_id: S7S_02955
symbol: rpsK
gene_biotype: protein_coding
description:
  30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.


ensembl_gene_id: S7S_02960
symbol: rpsD
gene_biotype: protein_coding
description:
  30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.


ensembl_gene_id: S7S_02965
symbol: rpoA
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: S7S_02980
symbol: uvrA
gene_biotype: protein_coding
description:
  Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.


ensembl_gene_id: S7S_02995
symbol: S7S_02995
gene_biotype: protein_coding
description:
  Single-stranded DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.


ensembl_gene_id: S7S_03025
symbol: S7S_03025
gene_biotype: protein_coding
description:
  Adenylate and guanylate cyclase catalytic domain-containing protein; COG0642 Signal transduction histidine kinase.


ensembl_gene_id: S7S_03050
symbol: S7S_03050
gene_biotype: protein_coding
description:
  Short chain dehydrogenase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: S7S_03065
symbol: S7S_03065
gene_biotype: protein_coding
description:
  Short chain dehydrogenase; COG3320 Putative dehydrogenase domain of multifunctional non-ribosomal peptide synthetases and related enzymes.


ensembl_gene_id: S7S_03135
symbol: S7S_03135
gene_biotype: protein_coding
description:
  Short chain dehydrogenase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: S7S_03145
symbol: S7S_03145
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases.


ensembl_gene_id: S7S_03170
symbol: rplU
gene_biotype: protein_coding
description:
  50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.


ensembl_gene_id: S7S_03180
symbol: obgE
gene_biotype: protein_coding
description:
  GTPase CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.


ensembl_gene_id: S7S_03185
symbol: proB
gene_biotype: protein_coding
description:
  Gamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.


ensembl_gene_id: S7S_03195
symbol: murJ
gene_biotype: protein_coding
description:
  Virulence factor MVIN-like protein; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.


ensembl_gene_id: S7S_03205
symbol: ileS
gene_biotype: protein_coding
description:
  isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.


ensembl_gene_id: S7S_03210
symbol: lspA-2
gene_biotype: protein_coding
description:
  Lipoprotein signal peptidase 2; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.


ensembl_gene_id: S7S_03220
symbol: ispH
gene_biotype: protein_coding
description:
  LytB protein; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.


ensembl_gene_id: S7S_03225
symbol: S7S_03225
gene_biotype: protein_coding
description:
  Putative type-4 fimbrial pilin related signal peptide protein; COG4970 Tfp pilus assembly protein FimT.


ensembl_gene_id: S7S_03270
symbol: S7S_03270
gene_biotype: protein_coding
description:
  Fis family transcriptional regulator; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains.


ensembl_gene_id: S7S_03285
symbol: nadE
gene_biotype: protein_coding
description:
  NAD+ synthase (Glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.


ensembl_gene_id: S7S_03290
symbol: bamD
gene_biotype: protein_coding
description:
  Outer membrane assembly lipoprotein YfiO; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: S7S_03295
symbol: S7S_03295
gene_biotype: protein_coding
description:
  Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.


ensembl_gene_id: S7S_03305
symbol: clpB
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease, ATP-binding subunit ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.


ensembl_gene_id: S7S_03315
symbol: S7S_03315
gene_biotype: protein_coding
description:
  Acetolactate synthase 3 catalytic subunit; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase].


ensembl_gene_id: S7S_03365
symbol: S7S_03365
gene_biotype: protein_coding
description:
  Glyoxalase/bleomycin resistance protein/dioxygenase; COG0346 Lactoylglutathione lyase and related lyases.


ensembl_gene_id: S7S_03440
symbol: S7S_03440
gene_biotype: protein_coding
description:
  6-aminohexanoate-dimer hydrolase; COG1680 Beta-lactamase class C and other penicillin binding proteins.


ensembl_gene_id: S7S_03465
symbol: ilvC
gene_biotype: protein_coding
description:
  Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.


ensembl_gene_id: S7S_03470
symbol: S7S_03470
gene_biotype: protein_coding
description:
  CDP-diacylglycerol--serine O-phosphatidyltransferase; COG1183 Phosphatidylserine synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: S7S_03495
symbol: S7S_03495
gene_biotype: protein_coding
description:
  Efflux transporter, RND family, MFP subunit; COG0845 Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: S7S_03500
symbol: S7S_03500
gene_biotype: protein_coding
description:
  RND transporter, HAE1/HME family, permease protein; COG0841 Cation/multidrug efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: S7S_03535
symbol: valS
gene_biotype: protein_coding
description:
  valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.


ensembl_gene_id: S7S_03550
symbol: pepA
gene_biotype: protein_coding
description:
  Cytosol aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.


ensembl_gene_id: S7S_03570
symbol: queA
gene_biotype: protein_coding
description:
  S-adenosylmethionine--tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).


ensembl_gene_id: S7S_03575
symbol: tgt
gene_biotype: protein_coding
description:
  Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...]


ensembl_gene_id: S7S_03580
symbol: yajC
gene_biotype: protein_coding
description:
  Preprotein translocase subunit YajC; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.


ensembl_gene_id: S7S_03585
symbol: secD-2
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.


ensembl_gene_id: S7S_03590
symbol: secF
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.


ensembl_gene_id: S7S_03595
symbol: S7S_03595
gene_biotype: protein_coding
description:
  Classes I and II superfamily aminotransferase; COG0436 Aspartate/tyrosine/aromatic aminotransferase.


ensembl_gene_id: S7S_03600
symbol: S7S_03600
gene_biotype: protein_coding
description:
  Amidase; COG0154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases; Belongs to the amidase family.


ensembl_gene_id: S7S_03605
symbol: S7S_03605
gene_biotype: protein_coding
description:
  D-isomer specific 2-hydroxyacid dehydrogenase family protein; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases.


ensembl_gene_id: S7S_03610
symbol: S7S_03610
gene_biotype: protein_coding
description:
  Aminotransferase; COG0160 4-aminobutyrate aminotransferase and related aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: S7S_03615
symbol: S7S_03615
gene_biotype: protein_coding
description:
  Dehydrogenase, isocitrate/isopropylmalate family protein; COG0473 Isocitrate/isopropylmalate dehydrogenase.


ensembl_gene_id: S7S_03620
symbol: S7S_03620
gene_biotype: protein_coding
description:
  Succinate-semialdehyde dehydrogenase subfamily protein; COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: S7S_03625
symbol: S7S_03625
gene_biotype: protein_coding
description:
  Type 12 methyltransferase; COG2227 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase.


ensembl_gene_id: S7S_03630
symbol: S7S_03630
gene_biotype: protein_coding
description:
  Inositol monophosphatase family protein; COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family.


ensembl_gene_id: S7S_03635
symbol: trmJ
gene_biotype: protein_coding
description:
  RNA methyltransferase; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.


ensembl_gene_id: S7S_03645
symbol: S7S_03645
gene_biotype: protein_coding
description:
  Iron-sulfur cluster assembly transcription factor IscR; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.


ensembl_gene_id: S7S_03655
symbol: S7S_03655
gene_biotype: protein_coding
description:
  XylDLEGF operon transcriptional activator 1; COG2207 AraC-type DNA-binding domain-containing proteins.


ensembl_gene_id: S7S_03665
symbol: potA
gene_biotype: protein_coding
description:
  Putrescine/spermidine ABC transporter ATPase protein; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.


ensembl_gene_id: S7S_03670
symbol: S7S_03670
gene_biotype: protein_coding
description:
  Binding-protein-dependent transport system inner membrane protein; COG1176 ABC-type spermidine/putrescine transport system, permease component I.


ensembl_gene_id: S7S_03675
symbol: potC
gene_biotype: protein_coding
description:
  Spermidine/putrescine ABC transporter membrane protein; COG1177 ABC-type spermidine/putrescine transport system, permease component II.


ensembl_gene_id: S7S_03680
symbol: S7S_03680
gene_biotype: protein_coding
description:
  Spermidine/putrescine ABC transporter substrate-binding protein; Required for the activity of the bacterial periplasmic transport system of putrescine; Belongs to the bacterial solute-binding protein PotD/PotF family.


ensembl_gene_id: S7S_03705
symbol: S7S_03705
gene_biotype: protein_coding
description:
  Fe-S metabolism associated domain-containing protein; COG2166 SufE protein probably involved in Fe-S center assembly.


ensembl_gene_id: S7S_03720
symbol: S7S_03720
gene_biotype: protein_coding
description:
  Cysteine desulfurase, SufS subfamily protein; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.


ensembl_gene_id: S7S_03725
symbol: S7S_03725
gene_biotype: protein_coding
description:
  ABC transporter permease; COG0719 ABC-type transport system involved in Fe-S cluster assembly, permease component.


ensembl_gene_id: S7S_03730
symbol: S7S_03730
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component.


ensembl_gene_id: S7S_03735
symbol: S7S_03735
gene_biotype: protein_coding
description:
  Cysteine desulfurase activator complex subunit SufB; COG0719 ABC-type transport system involved in Fe-S cluster assembly, permease component.


ensembl_gene_id: S7S_03740
symbol: ndk
gene_biotype: protein_coding
description:
  Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.


ensembl_gene_id: S7S_03745
symbol: rlmN
gene_biotype: protein_coding
description:
  Fe-S-cluster redox protein; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family.


ensembl_gene_id: S7S_03760
symbol: ispG
gene_biotype: protein_coding
description:
  1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family.


ensembl_gene_id: S7S_03775
symbol: bamB
gene_biotype: protein_coding
description:
  Outer membrane assembly lipoprotein YfgL; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: S7S_03780
symbol: der
gene_biotype: protein_coding
description:
  GTPase Der; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.


ensembl_gene_id: S7S_03800
symbol: xseA
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family.


ensembl_gene_id: S7S_03805
symbol: guaB
gene_biotype: protein_coding
description:
  Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.


ensembl_gene_id: S7S_03825
symbol: S7S_03825
gene_biotype: protein_coding
description:
  Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.


ensembl_gene_id: S7S_03840
symbol: S7S_03840
gene_biotype: protein_coding
description:
  Antitoxin of a toxin/antitoxin system, phd-like protein; Antitoxin component of a type II toxin-antitoxin (TA) system.


ensembl_gene_id: S7S_03865
symbol: S7S_03865
gene_biotype: protein_coding
description:
  Transcriptional regulatory protein PtsJ; COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs.


ensembl_gene_id: S7S_03890
symbol: azoR
gene_biotype: protein_coding
description:
  NAD(P)H dehydrogenase (Quinone); Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity; Belongs to the azoreductase type 1 family.


ensembl_gene_id: S7S_03895
symbol: S7S_03895
gene_biotype: protein_coding
description:
  Diacylglycerol kinase catalytic domain-containing protein; COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase.


ensembl_gene_id: S7S_03920
symbol: S7S_03920
gene_biotype: protein_coding
description:
  N-acetyltransferase family protein; COG2162 Arylamine N-acetyltransferase; Belongs to the arylamine N-acetyltransferase family.


ensembl_gene_id: S7S_03950
symbol: S7S_03950
gene_biotype: protein_coding
description:
  Sensory histidine kinase in two-component regulatory system with RstA; COG0642 Signal transduction histidine kinase.


ensembl_gene_id: S7S_03995
symbol: S7S_03995
gene_biotype: protein_coding
description:
  Zn-dependent hydrolase; COG3228 Uncharacterized protein conserved in bacteria; Belongs to the MtfA family.


ensembl_gene_id: S7S_04015
symbol: S7S_04015
gene_biotype: protein_coding
description:
  Excinuclease ABC subunit C; COG0861 Membrane protein TerC, possibly involved in tellurium resistance.


ensembl_gene_id: S7S_04020
symbol: S7S_04020
gene_biotype: protein_coding
description:
  Beta-hydroxylase, aspartyl/asparaginyl family protein; COG3555 Aspartyl/asparaginyl beta-hydroxylase and related dioxygenases.


ensembl_gene_id: S7S_04035
symbol: S7S_04035
gene_biotype: protein_coding
description:
  LysR family transcription regulator protein; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: S7S_04060
symbol: S7S_04060
gene_biotype: protein_coding
description:
  Auxiliary transport protein, MFP family; COG0845 Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: S7S_04085
symbol: purT
gene_biotype: protein_coding
description:
  Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family.


ensembl_gene_id: S7S_04090
symbol: tadA
gene_biotype: protein_coding
description:
  Cytidine/deoxycytidylate deaminase family protein; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.


ensembl_gene_id: S7S_04095
symbol: mltF
gene_biotype: protein_coding
description:
  Ligand-binding/transglycosylase domain-containing protein; Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.


ensembl_gene_id: S7S_04100
symbol: purL
gene_biotype: protein_coding
description:
  Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.


ensembl_gene_id: S7S_04140
symbol: S7S_04140
gene_biotype: protein_coding
description:
  FUR family transcriptional regulator; COG0735 Fe2+/Zn2+ uptake regulation proteins; Belongs to the Fur family.


ensembl_gene_id: S7S_04155
symbol: S7S_04155
gene_biotype: protein_coding
description:
  NUDIX family hydrolase; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes.


ensembl_gene_id: S7S_04170
symbol: S7S_04170
gene_biotype: protein_coding
description:
  Phospholipase, patatin family protein; COG1752 Predicted esterase of the alpha-beta hydrolase superfamily.


ensembl_gene_id: S7S_04185
symbol: S7S_04185
gene_biotype: protein_coding
description:
  Cytochrome C assembly protein; COG4137 ABC-type uncharacterized transport system, permease component.


ensembl_gene_id: S7S_04190
symbol: ffh
gene_biotype: protein_coding
description:
  Signal recognition particle protein Ffh; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual comp [...]


ensembl_gene_id: S7S_04200
symbol: rimM
gene_biotype: protein_coding
description:
  Ribosome maturation factor rimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family.


ensembl_gene_id: S7S_04205
symbol: trmD
gene_biotype: protein_coding
description:
  tRNA (guanine-N(1)-)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.


ensembl_gene_id: S7S_04210
symbol: rplS
gene_biotype: protein_coding
description:
  50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.


ensembl_gene_id: S7S_04220
symbol: xerD
gene_biotype: protein_coding
description:
  Integrase/recombinase XerD; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.


ensembl_gene_id: S7S_04225
symbol: S7S_04225
gene_biotype: protein_coding
description:
  Protein disulfide-isomerase; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily.


ensembl_gene_id: S7S_04240
symbol: S7S_04240
gene_biotype: protein_coding
description:
  Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.


ensembl_gene_id: S7S_04295
symbol: S7S_04295
gene_biotype: protein_coding
description:
  CAIB/BAIF family protein; COG1804 Predicted acyl-CoA transferases/carnitine dehydratase; Belongs to the CoA-transferase III family.


ensembl_gene_id: S7S_04310
symbol: S7S_04310
gene_biotype: protein_coding
description:
  COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain; Belongs to the peptidase S1C family.


ensembl_gene_id: S7S_04360
symbol: S7S_04360
gene_biotype: protein_coding
description:
  Lipocalin family protein; Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.


ensembl_gene_id: S7S_04450
symbol: S7S_04450
gene_biotype: protein_coding
description:
  Cyclic nucleotide-binding domain-containing protein; COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases.


ensembl_gene_id: S7S_04460
symbol: gatB
gene_biotype: protein_coding
description:
  aspartyl/glutamyl-tRNA amidotransferase subunit B; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily.


ensembl_gene_id: S7S_04465
symbol: gatA
gene_biotype: protein_coding
description:
  glutamyl-tRNA(Gln) amidotransferase subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln).


ensembl_gene_id: S7S_04470
symbol: gatC
gene_biotype: protein_coding
description:
  glutamyl-tRNA(Gln) amidotransferase subunit C; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family.


ensembl_gene_id: S7S_04485
symbol: S7S_04485
gene_biotype: protein_coding
description:
  Rod shape-determining protein MreD; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins. Belongs to the MreD family.


ensembl_gene_id: S7S_04490
symbol: S7S_04490
gene_biotype: protein_coding
description:
  Maf protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.


ensembl_gene_id: S7S_04510
symbol: S7S_04510
gene_biotype: protein_coding
description:
  Cyclic nucleotide-binding protein; COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases.


ensembl_gene_id: S7S_04540
symbol: S7S_04540
gene_biotype: protein_coding
description:
  Phosphotransferase system, nitrogen regulatory IIA protein; COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type).


ensembl_gene_id: S7S_04550
symbol: S7S_04550
gene_biotype: protein_coding
description:
  RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.


ensembl_gene_id: S7S_04555
symbol: S7S_04555
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG1137 ABC-type (unclassified) transport system, ATPase component.


ensembl_gene_id: S7S_04570
symbol: S7S_04570
gene_biotype: protein_coding
description:
  YrbI family phosphatase; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family.


ensembl_gene_id: S7S_04575
symbol: S7S_04575
gene_biotype: protein_coding
description:
  KpsF/GutQ family protein; COG0794 Predicted sugar phosphate isomerase involved in capsule formation.


ensembl_gene_id: S7S_04585
symbol: S7S_04585
gene_biotype: protein_coding
description:
  Toluene tolerance protein Ttg2D; COG2854 ABC-type transport system involved in resistance to organic solvents, auxiliary component.


ensembl_gene_id: S7S_04590
symbol: S7S_04590
gene_biotype: protein_coding
description:
  BolA-like protein; COG5007 Predicted transcriptional regulator, BolA superfamily; Belongs to the BolA/IbaG family.


ensembl_gene_id: S7S_04595
symbol: murA
gene_biotype: protein_coding
description:
  UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.


ensembl_gene_id: S7S_04600
symbol: hisG
gene_biotype: protein_coding
description:
  ATP phosphoribosyltransferase catalytic subunit; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily.


ensembl_gene_id: S7S_04605
symbol: hisD
gene_biotype: protein_coding
description:
  Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.


ensembl_gene_id: S7S_04610
symbol: hisC
gene_biotype: protein_coding
description:
  COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.


ensembl_gene_id: S7S_04625
symbol: S7S_04625
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase.


ensembl_gene_id: S7S_04665
symbol: cas1
gene_biotype: protein_coding
description:
  CRISPR associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.


ensembl_gene_id: S7S_04670
symbol: cas2
gene_biotype: protein_coding
description:
  CRISPR-associated Cas2 family protein; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.


ensembl_gene_id: S7S_04705
symbol: rplM
gene_biotype: protein_coding
description:
  50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.


ensembl_gene_id: S7S_04715
symbol: S7S_04715
gene_biotype: protein_coding
description:
  Ubiquinol-cytochrome c reductase iron-sulfur subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.


ensembl_gene_id: S7S_04720
symbol: S7S_04720
gene_biotype: protein_coding
description:
  Cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.


ensembl_gene_id: S7S_04750
symbol: gmhA
gene_biotype: protein_coding
description:
  Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.


ensembl_gene_id: S7S_04755
symbol: S7S_04755
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0792 Predicted endonuclease distantly related to archaeal Holliday junction resolvase; Belongs to the UPF0102 family.


ensembl_gene_id: S7S_04765
symbol: rsmI
gene_biotype: protein_coding
description:
  Tetrapyrrole methylase family protein; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.


ensembl_gene_id: S7S_04775
symbol: rsmH
gene_biotype: protein_coding
description:
  Ribosomal RNA small subunit methyltransferase H; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.


ensembl_gene_id: S7S_04780
symbol: ftsL
gene_biotype: protein_coding
description:
  Cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.


ensembl_gene_id: S7S_04785
symbol: ftsI
gene_biotype: protein_coding
description:
  Penicillin-binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.


ensembl_gene_id: S7S_04790
symbol: murE
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.


ensembl_gene_id: S7S_04795
symbol: murF
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alan ine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.


ensembl_gene_id: S7S_04800
symbol: mraY
gene_biotype: protein_coding
description:
  phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.


ensembl_gene_id: S7S_04805
symbol: murD
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.


ensembl_gene_id: S7S_04810
symbol: ftsW
gene_biotype: protein_coding
description:
  Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily.


ensembl_gene_id: S7S_04815
symbol: murG
gene_biotype: protein_coding
description:
  Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.


ensembl_gene_id: S7S_04825
symbol: ddl
gene_biotype: protein_coding
description:
  D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.


ensembl_gene_id: S7S_04830
symbol: ftsQ
gene_biotype: protein_coding
description:
  Cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.


ensembl_gene_id: S7S_04835
symbol: ftsA
gene_biotype: protein_coding
description:
  Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.


ensembl_gene_id: S7S_04840
symbol: ftsZ
gene_biotype: protein_coding
description:
  Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.


ensembl_gene_id: S7S_04845
symbol: lpxC
gene_biotype: protein_coding
description:
  UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family.


ensembl_gene_id: S7S_04860
symbol: secA
gene_biotype: protein_coding
description:
  Protein translocase subunit secA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family.


ensembl_gene_id: S7S_04865
symbol: argJ
gene_biotype: protein_coding
description:
  Bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.


ensembl_gene_id: S7S_04870
symbol: S7S_04870
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; Belongs to the Nudix hydrolase family.


ensembl_gene_id: S7S_04875
symbol: yacG
gene_biotype: protein_coding
description:
  Hypothetical protein; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C- terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.


ensembl_gene_id: S7S_04880
symbol: coaE
gene_biotype: protein_coding
description:
  dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.


ensembl_gene_id: S7S_04885
symbol: S7S_04885
gene_biotype: protein_coding
description:
  Leaderpeptidase and N-methyltransferase; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.


ensembl_gene_id: S7S_04890
symbol: S7S_04890
gene_biotype: protein_coding
description:
  Type II secretion system protein F domain-containing protein; COG1459 Type II secretory pathway, component PulF.


ensembl_gene_id: S7S_04900
symbol: S7S_04900
gene_biotype: protein_coding
description:
  Fimbrial protein; COG4969 Tfp pilus assembly protein, major pilin PilA; Belongs to the N-Me-Phe pilin family.


ensembl_gene_id: S7S_04905
symbol: S7S_04905
gene_biotype: protein_coding
description:
  Fimbrial assembly protein fimD, serogroup D; COG1680 Beta-lactamase class C and other penicillin binding proteins.


ensembl_gene_id: S7S_04970
symbol: S7S_04970
gene_biotype: protein_coding
description:
  N-acetyl-anhydromuranmyl-L-alanine amidase; COG3023 Negative regulator of beta-lactamase expression.


ensembl_gene_id: S7S_04980
symbol: aceE
gene_biotype: protein_coding
description:
  Pyruvate dehydrogenase subunit E1; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


ensembl_gene_id: S7S_04985
symbol: S7S_04985
gene_biotype: protein_coding
description:
  Pyruvate dehydrogenase, E2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


ensembl_gene_id: S7S_05020
symbol: S7S_05020
gene_biotype: protein_coding
description:
  2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.


ensembl_gene_id: S7S_05035
symbol: S7S_05035
gene_biotype: protein_coding
description:
  6-O-methylguanine DNA methyltransferase, DNA binding domain subfamily protein; COG3695 Predicted methylated DNA-protein cysteine methyltransferase.


ensembl_gene_id: S7S_05040
symbol: fabG
gene_biotype: protein_coding
description:
  3-ketoacyl-(acyl-carrier-protein) reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: S7S_05045
symbol: groS
gene_biotype: protein_coding
description:
  10 kDa chaperonin; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.


ensembl_gene_id: S7S_05050
symbol: groL
gene_biotype: protein_coding
description:
  60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.


ensembl_gene_id: S7S_05080
symbol: S7S_05080
gene_biotype: protein_coding
description:
  ATPase, histidine kinase-, DNA gyrase B-, and HSP90-like domain-containing protein; COG4585 Signal transduction histidine kinase.


ensembl_gene_id: S7S_05100
symbol: S7S_05100
gene_biotype: protein_coding
description:
  Putative outer membrane autotransporter barrel domain-containing protein; COG4625 Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain.


ensembl_gene_id: S7S_05105
symbol: S7S_05105
gene_biotype: protein_coding
description:
  Peptidase, S54 (Rhomboid) family protein; COG0705 Uncharacterized membrane protein (homolog of Drosophila rhomboid).


ensembl_gene_id: S7S_05115
symbol: S7S_05115
gene_biotype: protein_coding
description:
  Ribosomal-protein-alanine acetyltransferase; Acetylates the N-terminal alanine of ribosomal protein S18.


ensembl_gene_id: S7S_05155
symbol: S7S_05155
gene_biotype: protein_coding
description:
  Conserved repeat domain protein; COG0719 ABC-type transport system involved in Fe-S cluster assembly, permease component.


ensembl_gene_id: S7S_05170
symbol: prfC
gene_biotype: protein_coding
description:
  Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.


ensembl_gene_id: S7S_05175
symbol: S7S_05175
gene_biotype: protein_coding
description:
  Alkylphosphonate uptake protein; COG2824 Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism.


ensembl_gene_id: S7S_05180
symbol: S7S_05180
gene_biotype: protein_coding
description:
  Glyoxalase/bleomycin resistance protein/dioxygenase; COG2764 Uncharacterized protein conserved in bacteria.


ensembl_gene_id: S7S_05265
symbol: S7S_05265
gene_biotype: protein_coding
description:
  Glyoxylase 1; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.


ensembl_gene_id: S7S_05275
symbol: S7S_05275
gene_biotype: protein_coding
description:
  Extracytoplasmic-function sigma-70 factor; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: S7S_05290
symbol: S7S_05290
gene_biotype: protein_coding
description:
  Thioesterase domain-containing protein; COG3208 Predicted thioesterase involved in non-ribosomal peptide biosynthesis.


ensembl_gene_id: S7S_05305
symbol: S7S_05305
gene_biotype: protein_coding
description:
  Amino acid adenylation domain-containing protein; COG1020 Non-ribosomal peptide synthetase modules and related proteins.


ensembl_gene_id: S7S_05340
symbol: S7S_05340
gene_biotype: protein_coding
description:
  Fumarylacetoacetate hydrolase; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).


ensembl_gene_id: S7S_05350
symbol: S7S_05350
gene_biotype: protein_coding
description:
  phytanoyl-CoA dioxygenase (PhyH) family protein; COG5285 Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin.


ensembl_gene_id: S7S_05355
symbol: S7S_05355
gene_biotype: protein_coding
description:
  Monooxygenase FAD-binding protein; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.


ensembl_gene_id: S7S_05380
symbol: S7S_05380
gene_biotype: protein_coding
description:
  Oxidoreductase FAD-binding domain-containing protein; COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1.


ensembl_gene_id: S7S_05395
symbol: S7S_05395
gene_biotype: protein_coding
description:
  TonB-dependent siderophore receptor; COG4773 Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid.


ensembl_gene_id: S7S_05415
symbol: S7S_05415
gene_biotype: protein_coding
description:
  Pyoverdine synthetase E, pdvE; COG4615 ABC-type siderophore export system, fused ATPase and permease components.


ensembl_gene_id: S7S_05435
symbol: dsbD
gene_biotype: protein_coding
description:
  Thiol:disulfide interchange protein DsbD; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily.


ensembl_gene_id: S7S_05445
symbol: dsbG
gene_biotype: protein_coding
description:
  Disulfide isomerase/thiol-disulfide oxidase; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily.


ensembl_gene_id: S7S_05450
symbol: S7S_05450
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipi n synthases and related enzymes.


ensembl_gene_id: S7S_05465
symbol: S7S_05465
gene_biotype: protein_coding
description:
  Beta-ketoacyl synthase; COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: S7S_05475
symbol: S7S_05475
gene_biotype: protein_coding
description:
  Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.


ensembl_gene_id: S7S_05490
symbol: S7S_05490
gene_biotype: protein_coding
description:
  DNA integration/recombination/inversion protein; COG0582 Integrase; Belongs to the 'phage' integrase family.


ensembl_gene_id: S7S_05540
symbol: S7S_05540
gene_biotype: protein_coding
description:
  Adenine-specific DNA-methyltransferase; COG0286 Type I restriction-modification system methyltransferase subunit.


ensembl_gene_id: S7S_05550
symbol: S7S_05550
gene_biotype: protein_coding
description:
  Restriction modification system DNA specificity domain-containing protein; COG0732 Restriction endonuclease S subunits.


ensembl_gene_id: S7S_05555
symbol: S7S_05555
gene_biotype: protein_coding
description:
  HsdR family type I site-specific deoxyribonuclease; Subunit R is required for both nuclease and ATPase activities, but not for modification.


ensembl_gene_id: S7S_05650
symbol: S7S_05650
gene_biotype: protein_coding
description:
  ATP synthase, Delta/Epsilon chain, long alpha-helix domain-containing protein; COG4913 Uncharacterized protein conserved in bacteria.


ensembl_gene_id: S7S_05705
symbol: S7S_05705
gene_biotype: protein_coding
description:
  NAD dependent epimerase/dehydratase family protein; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: S7S_05720
symbol: dinB
gene_biotype: protein_coding
description:
  DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.


ensembl_gene_id: S7S_05730
symbol: S7S_05730
gene_biotype: protein_coding
description:
  FAD binding domain-containing protein; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.


ensembl_gene_id: S7S_05735
symbol: S7S_05735
gene_biotype: protein_coding
description:
  Serine endopeptidase/trypsin-like serine proteinase family protein; COG5640 Secreted trypsin-like serine protease.


ensembl_gene_id: S7S_05745
symbol: ppc
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family.


ensembl_gene_id: S7S_05820
symbol: S7S_05820
gene_biotype: protein_coding
description:
  Sodium/hydrogen exchanger; COG4651 Kef-type K+ transport system, predicted NAD-binding component; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.


ensembl_gene_id: S7S_05830
symbol: S7S_05830
gene_biotype: protein_coding
description:
  Quaternary ammonium compound-resistance protein; COG2076 Membrane transporters of cations and cationic drugs.


ensembl_gene_id: S7S_05835
symbol: S7S_05835
gene_biotype: protein_coding
description:
  Dehydrogenase; COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: S7S_05840
symbol: S7S_05840
gene_biotype: protein_coding
description:
  Acetolactate synthase; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Belongs to the TPP enzyme family.


ensembl_gene_id: S7S_05860
symbol: S7S_05860
gene_biotype: protein_coding
description:
  Ribonucleotide-diphosphate reductase subunit beta; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.


ensembl_gene_id: S7S_05865
symbol: S7S_05865
gene_biotype: protein_coding
description:
  Ribonucleotide-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.


ensembl_gene_id: S7S_05880
symbol: glpK
gene_biotype: protein_coding
description:
  Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.


ensembl_gene_id: S7S_05895
symbol: S7S_05895
gene_biotype: protein_coding
description:
  Toxin-antitoxin systems (TAS) HicB; COG4226 Uncharacterized protein encoded in hypervariable junctions of pilus gene clusters.


ensembl_gene_id: S7S_05905
symbol: S7S_05905
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG3842 ABC-type spermidine/putrescine transport systems, ATPase components; Belongs to the ABC transporter superfamily.


ensembl_gene_id: S7S_05910
symbol: S7S_05910
gene_biotype: protein_coding
description:
  Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.


ensembl_gene_id: S7S_05915
symbol: argD
gene_biotype: protein_coding
description:
  COG4992 Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.


ensembl_gene_id: S7S_06000
symbol: S7S_06000
gene_biotype: protein_coding
description:
  Monovalent cation/proton antiporter, MnhG/PhaG subunit; COG1320 Multisubunit Na+/H+ antiporter, MnhG subunit.


ensembl_gene_id: S7S_06005
symbol: S7S_06005
gene_biotype: protein_coding
description:
  Multiple resistance and pH regulation protein F; COG2212 Multisubunit Na+/H+ antiporter, MnhF subunit.


ensembl_gene_id: S7S_06015
symbol: S7S_06015
gene_biotype: protein_coding
description:
  Na(+) H(+) antiporter subunit D; COG0651 Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit.


ensembl_gene_id: S7S_06030
symbol: S7S_06030
gene_biotype: protein_coding
description:
  Monovalent cation/H+ antiporter subunit A; COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit.


ensembl_gene_id: S7S_06035
symbol: S7S_06035
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1721 Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain).


ensembl_gene_id: S7S_06070
symbol: S7S_06070
gene_biotype: protein_coding
description:
  Putative Trp repressor binding protein; COG0655 Multimeric flavodoxin WrbA; Belongs to the WrbA family.


ensembl_gene_id: S7S_06095
symbol: S7S_06095
gene_biotype: protein_coding
description:
  Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.


ensembl_gene_id: S7S_06140
symbol: S7S_06140
gene_biotype: protein_coding
description:
  HicB protein; COG4226 Uncharacterized protein encoded in hypervariable junctions of pilus gene clusters.


ensembl_gene_id: S7S_06150
symbol: S7S_06150
gene_biotype: protein_coding
description:
  Monooxygenase flavin-binding family protein; COG2072 Predicted flavoprotein involved in K+ transport.


ensembl_gene_id: S7S_06155
symbol: S7S_06155
gene_biotype: protein_coding
description:
  Short chain dehydrogenase/reductase family oxidoreductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: S7S_06165
symbol: S7S_06165
gene_biotype: protein_coding
description:
  COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: S7S_06230
symbol: proS
gene_biotype: protein_coding
description:
  prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...]


ensembl_gene_id: S7S_06285
symbol: S7S_06285
gene_biotype: protein_coding
description:
  COG0776 Bacterial nucleoid DNA-binding protein; Belongs to the bacterial histone-like protein family.


ensembl_gene_id: S7S_06290
symbol: aspS
gene_biotype: protein_coding
description:
  aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.


ensembl_gene_id: S7S_06300
symbol: ruvC
gene_biotype: protein_coding
description:
  Crossover junction endodeoxyribonuclease ruvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.


ensembl_gene_id: S7S_06305
symbol: ruvA
gene_biotype: protein_coding
description:
  Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.


ensembl_gene_id: S7S_06310
symbol: ruvB
gene_biotype: protein_coding
description:
  Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.


ensembl_gene_id: S7S_06320
symbol: tolQ
gene_biotype: protein_coding
description:
  Biopolymer transport protein TolQ; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: S7S_06325
symbol: tolR
gene_biotype: protein_coding
description:
  Biopolymer transport protein TolR; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: S7S_06335
symbol: tolB
gene_biotype: protein_coding
description:
  Protein tolB; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: S7S_06340
symbol: pal
gene_biotype: protein_coding
description:
  Peptidogycan-associated lipoprotein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: S7S_06345
symbol: cpoB
gene_biotype: protein_coding
description:
  Tol-pal system protein YbgF; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family.


ensembl_gene_id: S7S_06350
symbol: queE
gene_biotype: protein_coding
description:
  Radical activating enzyme; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.


ensembl_gene_id: S7S_06355
symbol: queC
gene_biotype: protein_coding
description:
  7-cyano-7-deazaguanine synthase 1; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.


ensembl_gene_id: S7S_06390
symbol: nadA
gene_biotype: protein_coding
description:
  Quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate; Belongs to the quinolinate synthase A family. Type 1 subfamily.


ensembl_gene_id: S7S_06395
symbol: rhlE
gene_biotype: protein_coding
description:
  ATP-dependent RNA helicase; DEAD-box RNA helicase involved in ribosome assembly. Has RNA- dependent ATPase activity and unwinds double-stranded RNA.


ensembl_gene_id: S7S_06400
symbol: S7S_06400
gene_biotype: protein_coding
description:
  M48 family peptidase; Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.


ensembl_gene_id: S7S_06405
symbol: S7S_06405
gene_biotype: protein_coding
description:
  Protein containing SirA-like domain; COG0425 Predicted redox protein, regulator of disulfide bond formation; Belongs to the sulfur carrier protein TusA family.


ensembl_gene_id: S7S_06425
symbol: dapA
gene_biotype: protein_coding
description:
  Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).


ensembl_gene_id: S7S_06435
symbol: S7S_06435
gene_biotype: protein_coding
description:
  Metallo-beta-lactamase superfamily protein; COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I.


ensembl_gene_id: S7S_06440
symbol: purC
gene_biotype: protein_coding
description:
  COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family.


ensembl_gene_id: S7S_06450
symbol: S7S_06450
gene_biotype: protein_coding
description:
  D-isomer specific 2-hydroxyacid dehydrogenase; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: S7S_06490
symbol: smc
gene_biotype: protein_coding
description:
  Chromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family.


ensembl_gene_id: S7S_06495
symbol: zipA
gene_biotype: protein_coding
description:
  Cell division protein ZipA; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.


ensembl_gene_id: S7S_06500
symbol: ligA
gene_biotype: protein_coding
description:
  NAD-dependent DNA ligase LigA; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily.


ensembl_gene_id: S7S_06525
symbol: metE
gene_biotype: protein_coding
description:
  5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.


ensembl_gene_id: S7S_06530
symbol: S7S_06530
gene_biotype: protein_coding
description:
  Transcriptional activator MetR; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: S7S_06545
symbol: S7S_06545
gene_biotype: protein_coding
description:
  LuxR family transcriptional regulator; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: S7S_06585
symbol: S7S_06585
gene_biotype: protein_coding
description:
  CoA-transferase family III family protein 5; COG1804 Predicted acyl-CoA transferases/carnitine dehydratase; Belongs to the CoA-transferase III family.


ensembl_gene_id: S7S_06605
symbol: S7S_06605
gene_biotype: protein_coding
description:
  CoA-transferase; COG1804 Predicted acyl-CoA transferases/carnitine dehydratase; Belongs to the CoA-transferase III family.


ensembl_gene_id: S7S_06625
symbol: S7S_06625
gene_biotype: protein_coding
description:
  Lipid-transfer protein; COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.


ensembl_gene_id: S7S_06660
symbol: S7S_06660
gene_biotype: protein_coding
description:
  Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: S7S_06665
symbol: S7S_06665
gene_biotype: protein_coding
description:
  COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: S7S_06670
symbol: S7S_06670
gene_biotype: protein_coding
description:
  COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: S7S_06710
symbol: S7S_06710
gene_biotype: protein_coding
description:
  Thioesterase superfamily protein; COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism.


ensembl_gene_id: S7S_06740
symbol: S7S_06740
gene_biotype: protein_coding
description:
  Hypothetical protein; COG3788 Uncharacterized relative of glutathione S-transferase, MAPEG superfamily.


ensembl_gene_id: S7S_06745
symbol: mnmC
gene_biotype: protein_coding
description:
  D-amino acid oxidase family protein; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family.


ensembl_gene_id: S7S_06765
symbol: S7S_06765
gene_biotype: protein_coding
description:
  NADH:flavin oxidoreductase/NADH Oxidase; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family.


ensembl_gene_id: S7S_06770
symbol: S7S_06770
gene_biotype: protein_coding
description:
  COG0300 Short-chain dehydrogenases of various substrate specificities; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: S7S_06805
symbol: dnaE2
gene_biotype: protein_coding
description:
  Error-prone DNA polymerase 2; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.


ensembl_gene_id: S7S_06815
symbol: S7S_06815
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases.


ensembl_gene_id: S7S_06870
symbol: S7S_06870
gene_biotype: protein_coding
description:
  4-carboxymuconolactone decarboxylase; COG0599 Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit.


ensembl_gene_id: S7S_06905
symbol: S7S_06905
gene_biotype: protein_coding
description:
  Outer membrane lipoprotein Blc; Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.


ensembl_gene_id: S7S_06910
symbol: ccmA
gene_biotype: protein_coding
description:
  Cytochrome c biogenesis ATP-binding export protein CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.


ensembl_gene_id: S7S_06915
symbol: S7S_06915
gene_biotype: protein_coding
description:
  Heme exporter protein B; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family.


ensembl_gene_id: S7S_06920
symbol: ccmC
gene_biotype: protein_coding
description:
  Heme exporter protein C; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family.


ensembl_gene_id: S7S_06925
symbol: S7S_06925
gene_biotype: protein_coding
description:
  Heme exporter protein CcmD; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmD/CycX/HelD family.


ensembl_gene_id: S7S_06930
symbol: ccmE
gene_biotype: protein_coding
description:
  Cytochrome c-type biogenesis protein CcmE; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family.


ensembl_gene_id: S7S_06940
symbol: S7S_06940
gene_biotype: protein_coding
description:
  Bacterioferritin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family.


ensembl_gene_id: S7S_06955
symbol: S7S_06955
gene_biotype: protein_coding
description:
  TRAP transporter 4TM/12TM fusion protein; COG4666 TRAP-type uncharacterized transport system, fused permease components.


ensembl_gene_id: S7S_06960
symbol: S7S_06960
gene_biotype: protein_coding
description:
  Benzoate 1,2-dioxygenase subunit alpha; COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit.


ensembl_gene_id: S7S_06970
symbol: S7S_06970
gene_biotype: protein_coding
description:
  Benzyl alcohol dehydrogenase; COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases.


ensembl_gene_id: S7S_06975
symbol: S7S_06975
gene_biotype: protein_coding
description:
  Oxidoreductase FAD-binding subunit; COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases.


ensembl_gene_id: S7S_06980
symbol: S7S_06980
gene_biotype: protein_coding
description:
  Glyoxalase/bleomycin resistance protein/dioxygenase superfamily protein 8; COG0346 Lactoylglutathione lyase and related lyases.


ensembl_gene_id: S7S_06995
symbol: S7S_06995
gene_biotype: protein_coding
description:
  Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.


ensembl_gene_id: S7S_07000
symbol: S7S_07000
gene_biotype: protein_coding
description:
  4-hyroxy-2-oxovalerate/4-hydroxy-2-oxopentanoic acid aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family.


ensembl_gene_id: S7S_07065
symbol: oadG
gene_biotype: protein_coding
description:
  Oxaloacetate decarboxylase subunit gamma; Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.


ensembl_gene_id: S7S_07075
symbol: S7S_07075
gene_biotype: protein_coding
description:
  Oxaloacetate decarboxylase subunit beta; Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation; Belongs to the GcdB/MmdB/OadB family.


ensembl_gene_id: S7S_07080
symbol: S7S_07080
gene_biotype: protein_coding
description:
  Oxidoreductase NAD-binding domain-containing protein; COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1.


ensembl_gene_id: S7S_07110
symbol: queF
gene_biotype: protein_coding
description:
  7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).


ensembl_gene_id: S7S_07190
symbol: S7S_07190
gene_biotype: protein_coding
description:
  Oxidoreductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: S7S_07195
symbol: S7S_07195
gene_biotype: protein_coding
description:
  LuxR family two component transcriptional regulator; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: S7S_07235
symbol: S7S_07235
gene_biotype: protein_coding
description:
  Aldehyde dehydrogenase (NAD) family protein; COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: S7S_07275
symbol: surE
gene_biotype: protein_coding
description:
  5'-nucleotidase surE 1; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.


ensembl_gene_id: S7S_07320
symbol: S7S_07320
gene_biotype: protein_coding
description:
  Two component LuxR family transcriptional regulator; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: S7S_07340
symbol: S7S_07340
gene_biotype: protein_coding
description:
  COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain.


ensembl_gene_id: S7S_07355
symbol: S7S_07355
gene_biotype: protein_coding
description:
  Quaternary ammonium efflux pump, 4 TMS small multidrug resistance (SMR) family, GacE; COG2076 Membrane transporters of cations and cationic drugs.


ensembl_gene_id: S7S_07365
symbol: selO
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation). Belongs to the SELO family.


ensembl_gene_id: S7S_07405
symbol: S7S_07405
gene_biotype: protein_coding
description:
  Heat-shock protein IbpA; COG0071 Molecular chaperone (small heat shock protein); Belongs to the small heat shock protein (HSP20) family.


ensembl_gene_id: S7S_07425
symbol: dnaX
gene_biotype: protein_coding
description:
  DNA polymerase III subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.


ensembl_gene_id: S7S_07430
symbol: S7S_07430
gene_biotype: protein_coding
description:
  Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.


ensembl_gene_id: S7S_07435
symbol: recR
gene_biotype: protein_coding
description:
  Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.


ensembl_gene_id: S7S_07500
symbol: pdxB
gene_biotype: protein_coding
description:
  Erythronate-4-phosphate dehydrogenase; Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate.


ensembl_gene_id: S7S_07515
symbol: htpX
gene_biotype: protein_coding
description:
  Protease HtpX; COG0501 Zn-dependent protease with chaperone function; Belongs to the peptidase M48B family.


ensembl_gene_id: S7S_07535
symbol: msrB
gene_biotype: protein_coding
description:
  methionine-R-sulfoxide reductase; COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase; Belongs to the MsrB Met sulfoxide reductase family.


ensembl_gene_id: S7S_07590
symbol: S7S_07590
gene_biotype: protein_coding
description:
  CcdB antidote CcdA; COG5302 Post-segregation antitoxin (ccd killing mechanism protein) encoded by the F plasmid.


ensembl_gene_id: S7S_07595
symbol: S7S_07595
gene_biotype: protein_coding
description:
  OmpA family protein; COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins.


ensembl_gene_id: S7S_07605
symbol: S7S_07605
gene_biotype: protein_coding
description:
  COG4987 ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components.


ensembl_gene_id: S7S_07610
symbol: S7S_07610
gene_biotype: protein_coding
description:
  ABC transporter permease/ATP-binding protein; COG4988 ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components.


ensembl_gene_id: S7S_07650
symbol: S7S_07650
gene_biotype: protein_coding
description:
  Efflux ABC transporter permease; COG3127 Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component.


ensembl_gene_id: S7S_07655
symbol: S7S_07655
gene_biotype: protein_coding
description:
  ABC transporter ATPase; COG4181 Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component.


ensembl_gene_id: S7S_07685
symbol: S7S_07685
gene_biotype: protein_coding
description:
  alpha-methylacyl-CoA racemase; COG1804 Predicted acyl-CoA transferases/carnitine dehydratase; Belongs to the CoA-transferase III family.


ensembl_gene_id: S7S_07705
symbol: S7S_07705
gene_biotype: protein_coding
description:
  Intracellular septation protein A; Involved in cell division; probably involved in intracellular septation; Belongs to the YciB family.


ensembl_gene_id: S7S_07710
symbol: S7S_07710
gene_biotype: protein_coding
description:
  Polymerase and histidinol phosphatase PHP; COG0613 Predicted metal-dependent phosphoesterases (PHP family).


ensembl_gene_id: S7S_07715
symbol: S7S_07715
gene_biotype: protein_coding
description:
  Sua5/YciO/YrdC/YwlC family protein; COG0009 Putative translation factor (SUA5); Belongs to the SUA5 family.


ensembl_gene_id: S7S_07720
symbol: trpS
gene_biotype: protein_coding
description:
  tryptophanyl-tRNA ligase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: S7S_07725
symbol: S7S_07725
gene_biotype: protein_coding
description:
  Excinuclease ABC subunit B; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.


ensembl_gene_id: S7S_07730
symbol: S7S_07730
gene_biotype: protein_coding
description:
  Transcriptional regulator; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.


ensembl_gene_id: S7S_07735
symbol: S7S_07735
gene_biotype: protein_coding
description:
  S4 domain-containing protein; COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; Belongs to the pseudouridine synthase RsuA family.


ensembl_gene_id: S7S_07750
symbol: S7S_07750
gene_biotype: protein_coding
description:
  16S ribosomal RNA methyltransferase RsmE; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.


ensembl_gene_id: S7S_07785
symbol: S7S_07785
gene_biotype: protein_coding
description:
  5'-Nucleotidase domain-containing protein; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases.


ensembl_gene_id: S7S_07840
symbol: S7S_07840
gene_biotype: protein_coding
description:
  Cobalt/zinc/cadmium efflux RND transporter permease; COG3696 Putative silver efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: S7S_07895
symbol: S7S_07895
gene_biotype: protein_coding
description:
  Transaldolase B; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 1 subfamily.


ensembl_gene_id: S7S_07900
symbol: dusA
gene_biotype: protein_coding
description:
  tRNA-dihydrouridine synthase A; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily.


ensembl_gene_id: S7S_07945
symbol: gltX
gene_biotype: protein_coding
description:
  glutamyl-tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.


ensembl_gene_id: S7S_07985
symbol: S7S_07985
gene_biotype: protein_coding
description:
  Succinate dehydrogenase, hydrophobic membrane anchor protein; Membrane-anchoring subunit of succinate dehydrogenase (SDH).


ensembl_gene_id: S7S_07990
symbol: sdhA
gene_biotype: protein_coding
description:
  COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.


ensembl_gene_id: S7S_08005
symbol: S7S_08005
gene_biotype: protein_coding
description:
  Dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).


ensembl_gene_id: S7S_08010
symbol: S7S_08010
gene_biotype: protein_coding
description:
  COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes.


ensembl_gene_id: S7S_08015
symbol: sucC
gene_biotype: protein_coding
description:
  succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.


ensembl_gene_id: S7S_08020
symbol: sucD
gene_biotype: protein_coding
description:
  succinyl-CoA ligase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.


ensembl_gene_id: S7S_08045
symbol: gpsA
gene_biotype: protein_coding
description:
  COG0240 Glycerol-3-phosphate dehydrogenase; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.


ensembl_gene_id: S7S_08085
symbol: S7S_08085
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: S7S_08135
symbol: S7S_08135
gene_biotype: protein_coding
description:
  Excitatory amino acid transporter; COG1301 Na+/H+-dicarboxylate symporters; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: S7S_08160
symbol: prmB
gene_biotype: protein_coding
description:
  N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue.


ensembl_gene_id: S7S_08165
symbol: aroC
gene_biotype: protein_coding
description:
  Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.


ensembl_gene_id: S7S_08170
symbol: S7S_08170
gene_biotype: protein_coding
description:
  Nucleoside:H+ symporter:Major facilitator superfamily protein; COG0477 Permeases of the major facilitator superfamily.


ensembl_gene_id: S7S_08185
symbol: S7S_08185
gene_biotype: protein_coding
description:
  Phospholipase; COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipi n synthases and related enzymes.


ensembl_gene_id: S7S_08200
symbol: leuC
gene_biotype: protein_coding
description:
  Isopropylmalate isomerase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.


ensembl_gene_id: S7S_08205
symbol: leuD
gene_biotype: protein_coding
description:
  Isopropylmalate isomerase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.


ensembl_gene_id: S7S_08210
symbol: leuB
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.


ensembl_gene_id: S7S_08215
symbol: asd
gene_biotype: protein_coding
description:
  Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.


ensembl_gene_id: S7S_08220
symbol: S7S_08220
gene_biotype: protein_coding
description:
  COG0136 Aspartate-semialdehyde dehydrogenase; Belongs to the aspartate-semialdehyde dehydrogenase family.


ensembl_gene_id: S7S_08230
symbol: truA
gene_biotype: protein_coding
description:
  tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.


ensembl_gene_id: S7S_08240
symbol: trpB
gene_biotype: protein_coding
description:
  Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.


ensembl_gene_id: S7S_08245
symbol: trpA
gene_biotype: protein_coding
description:
  Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.


ensembl_gene_id: S7S_08250
symbol: accD
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase, carboxyl transferase beta beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.


ensembl_gene_id: S7S_08265
symbol: S7S_08265
gene_biotype: protein_coding
description:
  Colicin V production protein; COG1286 Uncharacterized membrane protein, required for colicin V production.


ensembl_gene_id: S7S_08270
symbol: purF
gene_biotype: protein_coding
description:
  Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.


ensembl_gene_id: S7S_08275
symbol: metZ
gene_biotype: protein_coding
description:
  O-succinylhomoserine sulfhydrylase protein; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.


ensembl_gene_id: S7S_08295
symbol: ppnP
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.


ensembl_gene_id: S7S_08380
symbol: rne
gene_biotype: protein_coding
description:
  Phosphoric diester hydrolase; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily.


ensembl_gene_id: S7S_08405
symbol: S7S_08405
gene_biotype: protein_coding
description:
  Maf protein; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.


ensembl_gene_id: S7S_08420
symbol: plsX
gene_biotype: protein_coding
description:
  Phosphate acyltransferase; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.


ensembl_gene_id: S7S_08430
symbol: S7S_08430
gene_biotype: protein_coding
description:
  3-oxoacyl-ACP reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: S7S_08440
symbol: S7S_08440
gene_biotype: protein_coding
description:
  3-oxoacyl-ACP synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.


ensembl_gene_id: S7S_08445
symbol: S7S_08445
gene_biotype: protein_coding
description:
  Class IV aminotransferase; COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase.


ensembl_gene_id: S7S_08450
symbol: mltG
gene_biotype: protein_coding
description:
  Aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.


ensembl_gene_id: S7S_08455
symbol: tmk
gene_biotype: protein_coding
description:
  Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.


ensembl_gene_id: S7S_08515
symbol: S7S_08515
gene_biotype: protein_coding
description:
  Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP).


ensembl_gene_id: S7S_08520
symbol: cobB
gene_biotype: protein_coding
description:
  COG0846 NAD-dependent protein deacetylases, SIR2 family; Belongs to the sirtuin family. Class III subfamily.


ensembl_gene_id: S7S_08530
symbol: S7S_08530
gene_biotype: protein_coding
description:
  Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases.


ensembl_gene_id: S7S_08545
symbol: S7S_08545
gene_biotype: protein_coding
description:
  Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone.


ensembl_gene_id: S7S_08630
symbol: S7S_08630
gene_biotype: protein_coding
description:
  Carbamoyl-phosphate synthase ATP-binding subunit L; COG4770 Acetyl/propionyl-CoA carboxylase, alpha subunit.


ensembl_gene_id: S7S_08665
symbol: S7S_08665
gene_biotype: protein_coding
description:
  Ribonuclease activity regulator protein RraA; Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.


ensembl_gene_id: S7S_08685
symbol: S7S_08685
gene_biotype: protein_coding
description:
  CzcB family heavy metal RND efflux membrane fusion protein; COG0845 Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: S7S_08690
symbol: S7S_08690
gene_biotype: protein_coding
description:
  CzcA family heavy metal RND efflux protein; COG3696 Putative silver efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: S7S_08695
symbol: mdh
gene_biotype: protein_coding
description:
  Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.


ensembl_gene_id: S7S_08730
symbol: S7S_08730
gene_biotype: protein_coding
description:
  Response regulator receiver and ANTAR domain-containing protein; COG3707 Response regulator with putative antiterminator output domain.


ensembl_gene_id: S7S_08755
symbol: S7S_08755
gene_biotype: protein_coding
description:
  Nitrite reductase (NAD(P)H) large subunit; COG1251 NAD(P)H-nitrite reductase; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.


ensembl_gene_id: S7S_08770
symbol: S7S_08770
gene_biotype: protein_coding
description:
  Nitrate reductase; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.


ensembl_gene_id: S7S_08775
symbol: S7S_08775
gene_biotype: protein_coding
description:
  Precorrin-2 dehydrogenase; COG0007 Uroporphyrinogen-III methylase; Belongs to the precorrin methyltransferase family.


ensembl_gene_id: S7S_08805
symbol: S7S_08805
gene_biotype: protein_coding
description:
  OmpA/MotB domain-containing protein; COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins.


ensembl_gene_id: S7S_08820
symbol: S7S_08820
gene_biotype: protein_coding
description:
  COG3318 Predicted metal-binding protein related to the C-terminal domain of SecA; Belongs to the UPF0149 family.


ensembl_gene_id: S7S_08840
symbol: S7S_08840
gene_biotype: protein_coding
description:
  Oxidoreductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: S7S_08845
symbol: ttcA
gene_biotype: protein_coding
description:
  tRNA 2-thiocytidine biosynthesis protein TtcA; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.


ensembl_gene_id: S7S_08850
symbol: glcB
gene_biotype: protein_coding
description:
  Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.


ensembl_gene_id: S7S_08900
symbol: mnmA
gene_biotype: protein_coding
description:
  tRNA-specific 2-thiouridylase mnmA; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.


ensembl_gene_id: S7S_08905
symbol: nudJ
gene_biotype: protein_coding
description:
  NUDIX family hydrolase; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; Belongs to the Nudix hydrolase family. NudJ subfamily.


ensembl_gene_id: S7S_08910
symbol: moaC
gene_biotype: protein_coding
description:
  Molybdenum cofactor biosynthesis protein MoaC; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.


ensembl_gene_id: S7S_08920
symbol: moaE
gene_biotype: protein_coding
description:
  Molybdopterin guanine dinucleotide biosynthesis protein MoaE; COG0314 Molybdopterin converting factor, large subunit.


ensembl_gene_id: S7S_08925
symbol: S7S_08925
gene_biotype: protein_coding
description:
  Ribosomal large subunit pseudouridine synthase E; COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases.


ensembl_gene_id: S7S_08940
symbol: clpS
gene_biotype: protein_coding
description:
  Hypothetical protein; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family.


ensembl_gene_id: S7S_08945
symbol: S7S_08945
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease, ATP-binding subunitclpa; COG0542 ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family.


ensembl_gene_id: S7S_08950
symbol: infA
gene_biotype: protein_coding
description:
  Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.


ensembl_gene_id: S7S_08955
symbol: bpt
gene_biotype: protein_coding
description:
  arginyl-tRNA-protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate. Belongs to the R-transferase family. Bpt subfamily.


ensembl_gene_id: S7S_08960
symbol: aat
gene_biotype: protein_coding
description:
  leucyl/phenylalanyl-tRNA--protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.


ensembl_gene_id: S7S_08975
symbol: lolA
gene_biotype: protein_coding
description:
  Outer membrane lipoprotein carrier protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).


ensembl_gene_id: S7S_08980
symbol: S7S_08980
gene_biotype: protein_coding
description:
  Recombination factor protein RarA; COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase.


ensembl_gene_id: S7S_08985
symbol: serS
gene_biotype: protein_coding
description:
  seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).


ensembl_gene_id: S7S_08990
symbol: cysG
gene_biotype: protein_coding
description:
  uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family.  In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.


ensembl_gene_id: S7S_09005
symbol: S7S_09005
gene_biotype: protein_coding
description:
  Sulfur transfer complex subunit TusD; COG1553 Uncharacterized conserved protein involved in intracellular sulfur reduction.


ensembl_gene_id: S7S_09020
symbol: crcB
gene_biotype: protein_coding
description:
  Camphor resistance protein CrcB; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.


ensembl_gene_id: S7S_09025
symbol: crcB-2
gene_biotype: protein_coding
description:
  Hypothetical protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.


ensembl_gene_id: S7S_09035
symbol: uvrC
gene_biotype: protein_coding
description:
  UvrABC system protein C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.


ensembl_gene_id: S7S_09040
symbol: S7S_09040
gene_biotype: protein_coding
description:
  CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; COG0558 Phosphatidylglycerophosphate synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: S7S_09060
symbol: S7S_09060
gene_biotype: protein_coding
description:
  Protein-glutamate methylesterase; COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain.


ensembl_gene_id: S7S_09070
symbol: S7S_09070
gene_biotype: protein_coding
description:
  Type II secretory pathway, ATPase PulE-like protein; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.


ensembl_gene_id: S7S_09105
symbol: S7S_09105
gene_biotype: protein_coding
description:
  General secretion pathway protein L; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.


ensembl_gene_id: S7S_09110
symbol: S7S_09110
gene_biotype: protein_coding
description:
  General secretion pathway protein M; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.


ensembl_gene_id: S7S_09140
symbol: metH
gene_biotype: protein_coding
description:
  B12-dependent methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.


ensembl_gene_id: S7S_09155
symbol: S7S_09155
gene_biotype: protein_coding
description:
  NAD(P) transhydrogenase subunit beta; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.


ensembl_gene_id: S7S_09190
symbol: S7S_09190
gene_biotype: protein_coding
description:
  Transporter gate domain-containing protein; COG2715 Uncharacterized membrane protein, required for spore maturation in B.subtilis.


ensembl_gene_id: S7S_09200
symbol: corA
gene_biotype: protein_coding
description:
  Magnesium and cobalt transport protein CorA; Mediates influx of magnesium ions. Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.


ensembl_gene_id: S7S_09230
symbol: S7S_09230
gene_biotype: protein_coding
description:
  Transcriptional regulator Anr; COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases.


ensembl_gene_id: S7S_09235
symbol: S7S_09235
gene_biotype: protein_coding
description:
  COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductases; Belongs to the anaerobic coproporphyrinogen-III oxidase family.


ensembl_gene_id: S7S_09305
symbol: S7S_09305
gene_biotype: protein_coding
description:
  AbrB family transcriptional regulator; COG2002 Regulators of stationary/sporulation gene expression.


ensembl_gene_id: S7S_09310
symbol: S7S_09310
gene_biotype: protein_coding
description:
  Twitching motility protein PilT; COG5611 Predicted nucleic-acid-binding protein, contains PIN domain.


ensembl_gene_id: S7S_09390
symbol: S7S_09390
gene_biotype: protein_coding
description:
  Bcr/CflA family multidrug resistance transporter; COG0477 Permeases of the major facilitator superfamily.


ensembl_gene_id: S7S_09445
symbol: S7S_09445
gene_biotype: protein_coding
description:
  Puromycin N-acetyltransferase; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases.


ensembl_gene_id: S7S_09470
symbol: S7S_09470
gene_biotype: protein_coding
description:
  Thioesterase family protein; COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism.


ensembl_gene_id: S7S_09495
symbol: S7S_09495
gene_biotype: protein_coding
description:
  Glutathione reductase; COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes.


ensembl_gene_id: S7S_09505
symbol: S7S_09505
gene_biotype: protein_coding
description:
  COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains).


ensembl_gene_id: S7S_09510
symbol: S7S_09510
gene_biotype: protein_coding
description:
  Hypothetical protein; COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases.


ensembl_gene_id: S7S_09515
symbol: S7S_09515
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.


ensembl_gene_id: S7S_09520
symbol: S7S_09520
gene_biotype: protein_coding
description:
  PEP synthetase regulatory protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.


ensembl_gene_id: S7S_09565
symbol: S7S_09565
gene_biotype: protein_coding
description:
  2-methylcitrate synthase/citrate synthase II subfamily protein; COG0372 Citrate synthase; Belongs to the citrate synthase family.


ensembl_gene_id: S7S_09570
symbol: prpB
gene_biotype: protein_coding
description:
  2-methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.


ensembl_gene_id: S7S_09620
symbol: cysH
gene_biotype: protein_coding
description:
  Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.


ensembl_gene_id: S7S_09655
symbol: mtnA
gene_biotype: protein_coding
description:
  Initiation factor eIF-2B; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).


ensembl_gene_id: S7S_09660
symbol: mtnB
gene_biotype: protein_coding
description:
  Sugar aldolase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Belongs to the aldolase class II family. MtnB subfamily.


ensembl_gene_id: S7S_09665
symbol: mtnD
gene_biotype: protein_coding
description:
  ARD/ARD' family protein; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.


ensembl_gene_id: S7S_09680
symbol: S7S_09680
gene_biotype: protein_coding
description:
  Ribosomal ribonucleate guanine-2-methyltransferase; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.


ensembl_gene_id: S7S_09690
symbol: S7S_09690
gene_biotype: protein_coding
description:
  RND family efflux transporter, MFP subunit; COG0845 Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: S7S_09695
symbol: S7S_09695
gene_biotype: protein_coding
description:
  Acriflavin resistance protein; COG0841 Cation/multidrug efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: S7S_09700
symbol: S7S_09700
gene_biotype: protein_coding
description:
  Hypothetical protein; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family.


ensembl_gene_id: S7S_09705
symbol: rimO
gene_biotype: protein_coding
description:
  Ribosomal protein S12 methylthiotransferase RimO; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily.


ensembl_gene_id: S7S_09725
symbol: lon
gene_biotype: protein_coding
description:
  ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.


ensembl_gene_id: S7S_09730
symbol: S7S_09730
gene_biotype: protein_coding
description:
  Ribosomal large subunit pseudouridine synthase A; COG0564 Pseudouridylate synthases, 23S RNA-specific.


ensembl_gene_id: S7S_09740
symbol: msrA
gene_biotype: protein_coding
description:
  Methionine sulfoxide reductase A; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.


ensembl_gene_id: S7S_09755
symbol: nfuA
gene_biotype: protein_coding
description:
  Hypothetical protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.


ensembl_gene_id: S7S_09760
symbol: S7S_09760
gene_biotype: protein_coding
description:
  multidrug/Oligosaccharidyl-lipid/Polysaccharide flippase superfamily protein; COG0534 Na+-driven multidrug efflux pump.


ensembl_gene_id: S7S_09770
symbol: S7S_09770
gene_biotype: protein_coding
description:
  COG0155 Sulfite reductase, beta subunit (hemoprotein); Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.


ensembl_gene_id: S7S_09800
symbol: nudC
gene_biotype: protein_coding
description:
  NADH pyrophosphatase zinc ribbon domain family protein; COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding; Belongs to the Nudix hydrolase family. NudC subfamily.


ensembl_gene_id: S7S_09810
symbol: dnaQ
gene_biotype: protein_coding
description:
  DNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.


ensembl_gene_id: S7S_09825
symbol: gloB
gene_biotype: protein_coding
description:
  Hydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.


ensembl_gene_id: S7S_09840
symbol: S7S_09840
gene_biotype: protein_coding
description:
  Oligopeptide ABC transporter substrate-binding protein; COG4166 ABC-type oligopeptide transport system, periplasmic component.


ensembl_gene_id: S7S_09855
symbol: S7S_09855
gene_biotype: protein_coding
description:
  Oligopeptide ABC transporter ATP-binding protein; COG4172 ABC-type uncharacterized transport system, duplicated ATPase component; Belongs to the ABC transporter superfamily.


ensembl_gene_id: S7S_09870
symbol: S7S_09870
gene_biotype: protein_coding
description:
  DNA-binding protein HU; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.


ensembl_gene_id: S7S_09880
symbol: clpX
gene_biotype: protein_coding
description:
  ATP-dependent protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.


ensembl_gene_id: S7S_09885
symbol: clpP
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease, proteolytic subunitclpp; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.


ensembl_gene_id: S7S_09890
symbol: tig
gene_biotype: protein_coding
description:
  Trigger factor Tig; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.


ensembl_gene_id: S7S_09895
symbol: folD
gene_biotype: protein_coding
description:
  Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.


ensembl_gene_id: S7S_09905
symbol: S7S_09905
gene_biotype: protein_coding
description:
  Peptidyl-prolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.


ensembl_gene_id: S7S_09910
symbol: S7S_09910
gene_biotype: protein_coding
description:
  Cyclophilin type peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.


ensembl_gene_id: S7S_09915
symbol: lpxH
gene_biotype: protein_coding
description:
  UDP-2,3-diacylglucosamine hydrolase; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: S7S_09925
symbol: S7S_09925
gene_biotype: protein_coding
description:
  tRNA-(ms(2)io(6)a)-hydroxylase; COG4445 Hydroxylase for synthesis of 2-methylthio-cis-ribozeatin in tRNA.


ensembl_gene_id: S7S_09935
symbol: S7S_09935
gene_biotype: protein_coding
description:
  Bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; COG1049 Aconitase B; Belongs to the aconitase/IPM isomerase family.


ensembl_gene_id: S7S_09965
symbol: S7S_09965
gene_biotype: protein_coding
description:
  COG0394 Protein-tyrosine-phosphatase; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.


ensembl_gene_id: S7S_09970
symbol: kdsB
gene_biotype: protein_coding
description:
  3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.


ensembl_gene_id: S7S_09975
symbol: lpxK
gene_biotype: protein_coding
description:
  Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).


ensembl_gene_id: S7S_09980
symbol: msbA
gene_biotype: protein_coding
description:
  Lipid A export ATP-binding/permease MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.


ensembl_gene_id: S7S_10010
symbol: lolD
gene_biotype: protein_coding
description:
  Lipoprotein releasing system ATP-binding protein lolD; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner.


ensembl_gene_id: S7S_10025
symbol: S7S_10025
gene_biotype: protein_coding
description:
  Peptidyl-arginine deiminase family protein; COG2957 Peptidylarginine deiminase and related enzymes; Belongs to the agmatine deiminase family.


ensembl_gene_id: S7S_10040
symbol: S7S_10040
gene_biotype: protein_coding
description:
  N-acetylglutamate synthase / N-acetylglutamate kinase; COG1396 Predicted transcriptional regulators.


ensembl_gene_id: S7S_10065
symbol: S7S_10065
gene_biotype: protein_coding
description:
  Thiamine biosynthesis lipoprotein; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. Belongs to the ApbE family.


ensembl_gene_id: S7S_10070
symbol: nqrF
gene_biotype: protein_coding
description:
  Na(+)-translocating NADH-quinone reductase subunit F; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.


ensembl_gene_id: S7S_10075
symbol: nqrE
gene_biotype: protein_coding
description:
  Na(+)-translocating NADH-quinone reductase subunit E; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol; Belongs to the NqrDE/RnfAE family.


ensembl_gene_id: S7S_10080
symbol: nqrD
gene_biotype: protein_coding
description:
  Na(+)-translocating NADH-quinone reductase subunit D; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol; Belongs to the NqrDE/RnfAE family.


ensembl_gene_id: S7S_10085
symbol: nqrC
gene_biotype: protein_coding
description:
  Na(+)-translocating NADH-quinone reductase subunit C; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.


ensembl_gene_id: S7S_10090
symbol: nqrB
gene_biotype: protein_coding
description:
  Na(+)-translocating NADH-quinone reductase subunit B; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.


ensembl_gene_id: S7S_10095
symbol: nqrA
gene_biotype: protein_coding
description:
  Na(+)-translocating NADH-quinone reductase subunit A; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.


ensembl_gene_id: S7S_10115
symbol: mfd
gene_biotype: protein_coding
description:
  Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.


ensembl_gene_id: S7S_10135
symbol: S7S_10135
gene_biotype: protein_coding
description:
  Nucleoside phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine.


ensembl_gene_id: S7S_10150
symbol: nagZ
gene_biotype: protein_coding
description:
  Beta-hexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.


ensembl_gene_id: S7S_10165
symbol: S7S_10165
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1611 Predicted Rossmann fold nucleotide-binding protein; Belongs to the LOG family.


ensembl_gene_id: S7S_10175
symbol: topA
gene_biotype: protein_coding
description:
  DNA topoisomerase I subunit omega; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus rem [...]


ensembl_gene_id: S7S_10185
symbol: S7S_10185
gene_biotype: protein_coding
description:
  COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases.


ensembl_gene_id: S7S_10190
symbol: lexA
gene_biotype: protein_coding
description:
  LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.


ensembl_gene_id: S7S_10210
symbol: rlmL
gene_biotype: protein_coding
description:
  23S rRNA m(2)G2445 methyltransferase; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family.


ensembl_gene_id: S7S_10215
symbol: rmf
gene_biotype: protein_coding
description:
  Ribosome modulation factor; During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes); Belongs to the ribosome modulation factor family.


ensembl_gene_id: S7S_10220
symbol: pyrD
gene_biotype: protein_coding
description:
  Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.


ensembl_gene_id: S7S_10230
symbol: S7S_10230
gene_biotype: protein_coding
description:
  BNR repeat-containing protein; COG4447 Uncharacterized protein related to plant photosystem II stability/assembly factor.


ensembl_gene_id: S7S_10255
symbol: nadK
gene_biotype: protein_coding
description:
  Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.


ensembl_gene_id: S7S_10345
symbol: S7S_10345
gene_biotype: protein_coding
description:
  Putative oxidoreductase; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.


ensembl_gene_id: S7S_10350
symbol: cmoB
gene_biotype: protein_coding
description:
  tRNA mo(5)U34 methyltransferase; Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L- methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5- carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.


ensembl_gene_id: S7S_10355
symbol: cmoA
gene_biotype: protein_coding
description:
  tRNA (cmo5U34)-methyltransferase; Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).


ensembl_gene_id: S7S_10365
symbol: ihfA
gene_biotype: protein_coding
description:
  Integration host factor subunit alpha; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.


ensembl_gene_id: S7S_10370
symbol: pheT
gene_biotype: protein_coding
description:
  phenylalanyl-tRNA synthetase subunit beta; COG0073 EMAP domain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.


ensembl_gene_id: S7S_10375
symbol: pheS
gene_biotype: protein_coding
description:
  COG0016 Phenylalanyl-tRNA synthetase alpha subunit; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.


ensembl_gene_id: S7S_10380
symbol: rplT
gene_biotype: protein_coding
description:
  50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.


ensembl_gene_id: S7S_10390
symbol: infC
gene_biotype: protein_coding
description:
  Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.


ensembl_gene_id: S7S_10400
symbol: uvrB
gene_biotype: protein_coding
description:
  Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate  [...]


ensembl_gene_id: S7S_10415
symbol: cysN
gene_biotype: protein_coding
description:
  Sulfate adenylyltransferase, large subunit; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.


ensembl_gene_id: S7S_10420
symbol: cysD
gene_biotype: protein_coding
description:
  Sulfate adenylyltransferase subunit 2; COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes.


ensembl_gene_id: S7S_10485
symbol: S7S_10485
gene_biotype: protein_coding
description:
  DegT/DnrJ/EryC1/StrS family aminotransferase; COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; Belongs to the DegT/DnrJ/EryC1 family.


ensembl_gene_id: S7S_10515
symbol: S7S_10515
gene_biotype: protein_coding
description:
  Sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family protein; COG0110 Acetyltransferase (isoleucine patch superfamily).


ensembl_gene_id: S7S_10525
symbol: S7S_10525
gene_biotype: protein_coding
description:
  COG0381 UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family.


ensembl_gene_id: S7S_10545
symbol: S7S_10545
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0187 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit.


ensembl_gene_id: S7S_10570
symbol: S7S_10570
gene_biotype: protein_coding
description:
  COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.


ensembl_gene_id: S7S_10605
symbol: S7S_10605
gene_biotype: protein_coding
description:
  Beta-lactamase domain-containing protein; COG1236 Predicted exonuclease of the beta-lactamase fold involved in RNA processing.


ensembl_gene_id: S7S_10650
symbol: S7S_10650
gene_biotype: protein_coding
description:
  Low molecular weight phosphotyrosine protein phosphatase; COG0394 Protein-tyrosine-phosphatase; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.


ensembl_gene_id: S7S_10670
symbol: S7S_10670
gene_biotype: protein_coding
description:
  HipA domain-containing protein; COG3550 Uncharacterized protein related to capsule biosynthesis enzymes.


ensembl_gene_id: S7S_10690
symbol: pyrF
gene_biotype: protein_coding
description:
  Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.


ensembl_gene_id: S7S_10695
symbol: lapB
gene_biotype: protein_coding
description:
  Tetratricopeptide repeat protein; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane; Belongs to the LapB family.


ensembl_gene_id: S7S_10705
symbol: ihfB
gene_biotype: protein_coding
description:
  Integration host factor subunit beta; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.


ensembl_gene_id: S7S_10710
symbol: rpsA
gene_biotype: protein_coding
description:
  30S ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.


ensembl_gene_id: S7S_10720
symbol: aroA
gene_biotype: protein_coding
description:
  Bifunctional cyclohexadienyl dehydrogenase/ 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.


ensembl_gene_id: S7S_10735
symbol: serC
gene_biotype: protein_coding
description:
  3-phosphoserine/phosphohydroxythreonine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.


ensembl_gene_id: S7S_10740
symbol: gyrA
gene_biotype: protein_coding
description:
  DNA gyrase subunit A-like protein; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.


ensembl_gene_id: S7S_10745
symbol: mtaD
gene_biotype: protein_coding
description:
  N-ethylammeline chlorohydrolase; Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.


ensembl_gene_id: S7S_10750
symbol: ubiG
gene_biotype: protein_coding
description:
  3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family.


ensembl_gene_id: S7S_10760
symbol: S7S_10760
gene_biotype: protein_coding
description:
  Short chain dehydrogenase/reductase family oxidoreductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: S7S_10790
symbol: S7S_10790
gene_biotype: protein_coding
description:
  Hypothetical protein; COG4664 TRAP-type mannitol/chloroaromatic compound transport system, large permease component.


ensembl_gene_id: S7S_10795
symbol: S7S_10795
gene_biotype: protein_coding
description:
  TRAP transporter, DctM-like membrane protein; COG4664 TRAP-type mannitol/chloroaromatic compound transport system, large permease component.


ensembl_gene_id: S7S_10805
symbol: S7S_10805
gene_biotype: protein_coding
description:
  HIT family protein; COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases.


ensembl_gene_id: S7S_10825
symbol: rnd
gene_biotype: protein_coding
description:
  Ribonuclease D; Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides; Belongs to the RNase D family.


ensembl_gene_id: S7S_10835
symbol: gpmA
gene_biotype: protein_coding
description:
  Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.


ensembl_gene_id: S7S_10845
symbol: S7S_10845
gene_biotype: protein_coding
description:
  HlyD family secretion protein; COG0845 Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: S7S_10875
symbol: lifO
gene_biotype: protein_coding
description:
  Lipase chaperone; May be involved in the folding of the extracellular lipase during its passage through the periplasm; Belongs to the lipase chaperone family.


ensembl_gene_id: S7S_10885
symbol: S7S_10885
gene_biotype: protein_coding
description:
  Alpha/beta fold family hydrolase; COG1075 Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold.


ensembl_gene_id: S7S_10905
symbol: tusA
gene_biotype: protein_coding
description:
  Sulfurtransferase tusA-like protein; Sulfur carrier protein which probably makes part of a sulfur- relay system; Belongs to the sulfur carrier protein TusA family.


ensembl_gene_id: S7S_10915
symbol: S7S_10915
gene_biotype: protein_coding
description:
  Antibiotic biosynthesis monooxygenase; COG2329 Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides.


ensembl_gene_id: S7S_10920
symbol: S7S_10920
gene_biotype: protein_coding
description:
  23S rRNA C2498 ribose 2'-O-ribose methyltransferase; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.


ensembl_gene_id: S7S_10930
symbol: purU
gene_biotype: protein_coding
description:
  Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).


ensembl_gene_id: S7S_10940
symbol: S7S_10940
gene_biotype: protein_coding
description:
  Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: S7S_10950
symbol: S7S_10950
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain.


ensembl_gene_id: S7S_10995
symbol: S7S_10995
gene_biotype: protein_coding
description:
  Potassium efflux system protein; COG0475 Kef-type K+ transport systems, membrane components; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.


ensembl_gene_id: S7S_11005
symbol: S7S_11005
gene_biotype: protein_coding
description:
  TrkA domain-containing protein; COG1226 Kef-type K+ transport systems, predicted NAD-binding component.


ensembl_gene_id: S7S_11030
symbol: S7S_11030
gene_biotype: protein_coding
description:
  COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins; Belongs to the outer membrane OOP (TC 1.B.6) superfamily.


ensembl_gene_id: S7S_11070
symbol: S7S_11070
gene_biotype: protein_coding
description:
  Fatty oxidation complex subunit alpha; COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: S7S_11090
symbol: S7S_11090
gene_biotype: protein_coding
description:
  rimK-like ATP-grasp domain family protein; COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase).


ensembl_gene_id: S7S_11165
symbol: csrA
gene_biotype: protein_coding
description:
  Carbon storage regulator CsrA; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).


ensembl_gene_id: S7S_11175
symbol: alaS
gene_biotype: protein_coding
description:
  Phosphoserine aminotransferase, Methanosarcina type; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.


ensembl_gene_id: S7S_11185
symbol: recA
gene_biotype: protein_coding
description:
  recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.


ensembl_gene_id: S7S_11190
symbol: S7S_11190
gene_biotype: protein_coding
description:
  CinA domain-containing protein; COG1546 Uncharacterized protein (competence- and mitomycin-induced); Belongs to the CinA family.


ensembl_gene_id: S7S_11205
symbol: S7S_11205
gene_biotype: protein_coding
description:
  Phospholipase D active site motif protein 5; COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipi n synthases and related enzymes.


ensembl_gene_id: S7S_11365
symbol: S7S_11365
gene_biotype: protein_coding
description:
  Efflux transporter RND family, MFP subunit; COG0845 Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: S7S_11370
symbol: S7S_11370
gene_biotype: protein_coding
description:
  RND transporter HAE1/HME family, permease; COG0841 Cation/multidrug efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: S7S_11485
symbol: mutS
gene_biotype: protein_coding
description:
  DNA mismatch repair protein mutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.


ensembl_gene_id: S7S_11490
symbol: S7S_11490
gene_biotype: protein_coding
description:
  Ferredoxin, 4Fe-4S; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.


ensembl_gene_id: S7S_11525
symbol: S7S_11525
gene_biotype: protein_coding
description:
  Cardiolipin synthase; COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipi n synthases and related enzymes.


ensembl_gene_id: S7S_11545
symbol: S7S_11545
gene_biotype: protein_coding
description:
  Soluble pyridine nucleotide transhydrogenase; COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes.


ensembl_gene_id: S7S_11560
symbol: S7S_11560
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0593 ATPase involved in DNA replication initiation; Belongs to the DnaA family. HdA subfamily.


ensembl_gene_id: S7S_11570
symbol: purM
gene_biotype: protein_coding
description:
  Phosphoribosylformylglycinamidine cyclo-ligase; COG0150 Phosphoribosylaminoimidazole (AIR) synthetase.


ensembl_gene_id: S7S_11575
symbol: purN
gene_biotype: protein_coding
description:
  Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.


ensembl_gene_id: S7S_11595
symbol: S7S_11595
gene_biotype: protein_coding
description:
  Mrp/Nbp35 family ATP-binding protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.


ensembl_gene_id: S7S_11745
symbol: metG
gene_biotype: protein_coding
description:
  methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.


ensembl_gene_id: S7S_11755
symbol: S7S_11755
gene_biotype: protein_coding
description:
  Alkyl hydroperoxide reductase subunit C; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.


ensembl_gene_id: S7S_11785
symbol: S7S_11785
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0188 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit.


ensembl_gene_id: S7S_11795
symbol: S7S_11795
gene_biotype: protein_coding
description:
  COG5265 ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components.


ensembl_gene_id: S7S_11800
symbol: S7S_11800
gene_biotype: protein_coding
description:
  Flavin-dependent oxidoreductase; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: S7S_11835
symbol: S7S_11835
gene_biotype: protein_coding
description:
  Putative permease, DMT superfamily protein; COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily.


ensembl_gene_id: S7S_11850
symbol: S7S_11850
gene_biotype: protein_coding
description:
  Molybdopterin dinucleotide-binding region; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing.


ensembl_gene_id: S7S_11860
symbol: rnfA
gene_biotype: protein_coding
description:
  Electron transport complex protein RnfA; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.


ensembl_gene_id: S7S_11865
symbol: rnfB
gene_biotype: protein_coding
description:
  Electron transport complex protein RnfB; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.


ensembl_gene_id: S7S_11870
symbol: rnfC
gene_biotype: protein_coding
description:
  NADH:ubiquinone oxidoreductase, subunit RnfC; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.


ensembl_gene_id: S7S_11875
symbol: rnfD
gene_biotype: protein_coding
description:
  Electron transport complex protein rnfD; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the NqrB/RnfD family.


ensembl_gene_id: S7S_11880
symbol: rnfG
gene_biotype: protein_coding
description:
  Electron complex protein rnfG; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the RnfG family.


ensembl_gene_id: S7S_11885
symbol: rnfE
gene_biotype: protein_coding
description:
  Electron transport complex RsxE subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.


ensembl_gene_id: S7S_11905
symbol: nth
gene_biotype: protein_coding
description:
  Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.


ensembl_gene_id: S7S_11910
symbol: S7S_11910
gene_biotype: protein_coding
description:
  O-antigen polymerase family protein/toluene tolerance protein; COG0515 Serine/threonine protein kinase.


ensembl_gene_id: S7S_11920
symbol: rimK
gene_biotype: protein_coding
description:
  COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase); Belongs to the RimK family.


ensembl_gene_id: S7S_11930
symbol: S7S_11930
gene_biotype: protein_coding
description:
  Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.


ensembl_gene_id: S7S_11935
symbol: argG
gene_biotype: protein_coding
description:
  COG0137 Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.


ensembl_gene_id: S7S_11940
symbol: rnt
gene_biotype: protein_coding
description:
  Ribonuclease T; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.


ensembl_gene_id: S7S_11950
symbol: S7S_11950
gene_biotype: protein_coding
description:
  Cation efflux family protein; COG0053 Predicted Co/Zn/Cd cation transporters; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.


ensembl_gene_id: S7S_11965
symbol: pcm
gene_biotype: protein_coding
description:
  protein-L-isoaspartate(D-aspartate) O-methyltransferase; Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.


ensembl_gene_id: S7S_11970
symbol: truD
gene_biotype: protein_coding
description:
  tRNA pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family.


ensembl_gene_id: S7S_11975
symbol: ispF
gene_biotype: protein_coding
description:
  2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).


ensembl_gene_id: S7S_11980
symbol: ispD
gene_biotype: protein_coding
description:
  2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).


ensembl_gene_id: S7S_11985
symbol: ftsB
gene_biotype: protein_coding
description:
  Septum formation initiator subfamily protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.


ensembl_gene_id: S7S_11990
symbol: eno
gene_biotype: protein_coding
description:
  Enolase 1; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.


ensembl_gene_id: S7S_11995
symbol: kdsA
gene_biotype: protein_coding
description:
  2-dehydro-3-deoxyphosphooctonate aldolase; COG2877 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; Belongs to the KdsA family.


ensembl_gene_id: S7S_12000
symbol: pyrG
gene_biotype: protein_coding
description:
  CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.


ensembl_gene_id: S7S_12005
symbol: tilS
gene_biotype: protein_coding
description:
  tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.


ensembl_gene_id: S7S_12010
symbol: accA
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.


ensembl_gene_id: S7S_12015
symbol: S7S_12015
gene_biotype: protein_coding
description:
  TonB-dependent receptor domain-containing protein; COG4771 Outer membrane receptor for ferrienterochelin and colicins.


ensembl_gene_id: S7S_12035
symbol: lpxB
gene_biotype: protein_coding
description:
  Lipid A disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: S7S_12040
symbol: lpxA
gene_biotype: protein_coding
description:
  acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: S7S_12045
symbol: fabZ
gene_biotype: protein_coding
description:
  (3R)-hydroxymyristoyl-ACP dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.


ensembl_gene_id: S7S_12050
symbol: lpxD
gene_biotype: protein_coding
description:
  UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily.


ensembl_gene_id: S7S_12060
symbol: bamA
gene_biotype: protein_coding
description:
  Outer membrane protein surface antigen family protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: S7S_12070
symbol: dxr
gene_biotype: protein_coding
description:
  1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family.


ensembl_gene_id: S7S_12080
symbol: uppS
gene_biotype: protein_coding
description:
  Undecaprenyl pyrophosphate synthetase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.


ensembl_gene_id: S7S_12085
symbol: frr
gene_biotype: protein_coding
description:
  Ribosome-recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.


ensembl_gene_id: S7S_12095
symbol: tsf
gene_biotype: protein_coding
description:
  Translation elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.


ensembl_gene_id: S7S_12105
symbol: map
gene_biotype: protein_coding
description:
  Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.


ensembl_gene_id: S7S_12110
symbol: glnD
gene_biotype: protein_coding
description:
  PII uridylyl-transferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.


ensembl_gene_id: S7S_12120
symbol: S7S_12120
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1393 Arsenate reductase and related proteins, glutaredoxin family; Belongs to the ArsC family.


ensembl_gene_id: S7S_12125
symbol: dapD-2
gene_biotype: protein_coding
description:
  2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.


ensembl_gene_id: S7S_12130
symbol: dapE
gene_biotype: protein_coding
description:
  Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily.


ensembl_gene_id: S7S_12160
symbol: S7S_12160
gene_biotype: protein_coding
description:
  Nucleoprotein/polynucleotide-associated enzyme; COG3122 Uncharacterized protein conserved in bacteria.


ensembl_gene_id: S7S_12170
symbol: S7S_12170
gene_biotype: protein_coding
description:
  Allophanate hydrolase; COG0154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases.


ensembl_gene_id: S7S_12210
symbol: S7S_12210
gene_biotype: protein_coding
description:
  ABC transporter substrate-binding protein; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components.


ensembl_gene_id: S7S_12240
symbol: uppP
gene_biotype: protein_coding
description:
  Bacitracin resistance protein BacA/undecaprenol kinase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.


ensembl_gene_id: S7S_12250
symbol: S7S_12250
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone.


ensembl_gene_id: S7S_12260
symbol: mobA
gene_biotype: protein_coding
description:
  Molybdopterin-guanine dinucleotide biosynthesis protein MobA; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family.


ensembl_gene_id: S7S_12270
symbol: minE
gene_biotype: protein_coding
description:
  Cell division topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.


ensembl_gene_id: S7S_12280
symbol: minC
gene_biotype: protein_coding
description:
  Septum site-determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family.


ensembl_gene_id: S7S_12285
symbol: adk
gene_biotype: protein_coding
description:
  Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.


ensembl_gene_id: S7S_12300
symbol: S7S_12300
gene_biotype: protein_coding
description:
  Periplasmic protein thiol:disulfide oxidoreductase, DsbE subfamily; COG0526 Thiol-disulfide isomerase and thioredoxins.


ensembl_gene_id: S7S_12310
symbol: fabA
gene_biotype: protein_coding
description:
  3-hydroxydecanoyl-(acyl carrier protein) dehydratase; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.


ensembl_gene_id: S7S_12315
symbol: S7S_12315
gene_biotype: protein_coding
description:
  3-oxoacyl-ACP synthase; COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: S7S_12340
symbol: S7S_12340
gene_biotype: protein_coding
description:
  DNA-3-methyladenine glycosylase II; COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase.


ensembl_gene_id: S7S_12355
symbol: rlmD
gene_biotype: protein_coding
description:
  RNA methyltransferase; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.


ensembl_gene_id: S7S_12370
symbol: acpS
gene_biotype: protein_coding
description:
  Holo-[acyl-carrier-protein] synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.


ensembl_gene_id: S7S_12375
symbol: pdxJ
gene_biotype: protein_coding
description:
  Pyridoxine 5'-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.


ensembl_gene_id: S7S_12380
symbol: S7S_12380
gene_biotype: protein_coding
description:
  GNAT family acetyltransferase; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases.


ensembl_gene_id: S7S_12395
symbol: era
gene_biotype: protein_coding
description:
  GTP-binding protein Era-like-protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.


ensembl_gene_id: S7S_12400
symbol: rnc
gene_biotype: protein_coding
description:
  Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.


ensembl_gene_id: S7S_12415
symbol: lepA
gene_biotype: protein_coding
description:
  GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.


ensembl_gene_id: S7S_12420
symbol: S7S_12420
gene_biotype: protein_coding
description:
  Alginate biosynthesis negative regulator, serine protease; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain; Belongs to the peptidase S1C family.


ensembl_gene_id: S7S_12505
symbol: S7S_12505
gene_biotype: protein_coding
description:
  Methylmalonate semialdehyde dehydrogenase (Acylating); COG1012 NAD-dependent aldehyde dehydrogenases.


ensembl_gene_id: S7S_12515
symbol: ung
gene_biotype: protein_coding
description:
  uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.


ensembl_gene_id: S7S_12530
symbol: S7S_12530
gene_biotype: protein_coding
description:
  Peptide chain release factor 1; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.


ensembl_gene_id: S7S_12545
symbol: fadB
gene_biotype: protein_coding
description:
  Multifunctional fatty acid oxidation complex subunit alpha; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: S7S_12550
symbol: fadA
gene_biotype: protein_coding
description:
  3-ketoacyl-CoA thiolase; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.


ensembl_gene_id: S7S_12640
symbol: S7S_12640
gene_biotype: protein_coding
description:
  RND family efflux transporter MFP subunit; COG0845 Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: S7S_12650
symbol: S7S_12650
gene_biotype: protein_coding
description:
  Two component transcriptional regulator, winged helix family protein; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: S7S_12750
symbol: S7S_12750
gene_biotype: protein_coding
description:
  Outer membrane protein transport protein (OMPP1/FadL/TodX); COG1066 Predicted ATP-dependent serine protease.


ensembl_gene_id: S7S_12785
symbol: S7S_12785
gene_biotype: protein_coding
description:
  Hypothetical protein; COG2026 Cytotoxic translational repressor of toxin-antitoxin stability system.


ensembl_gene_id: S7S_12820
symbol: S7S_12820
gene_biotype: protein_coding
description:
  Thiol:disulfide interchange protein; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily.


ensembl_gene_id: S7S_12980
symbol: S7S_12980
gene_biotype: protein_coding
description:
  HicB family protein; COG4226 Uncharacterized protein encoded in hypervariable junctions of pilus gene clusters.


ensembl_gene_id: S7S_12985
symbol: deaD
gene_biotype: protein_coding
description:
  ATP-dependent RNA helicase; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.


ensembl_gene_id: S7S_12995
symbol: S7S_12995
gene_biotype: protein_coding
description:
  DNA-binding heavy metal response regulator; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: S7S_13040
symbol: S7S_13040
gene_biotype: protein_coding
description:
  Secreted protein containing outer membrane protein, OmpA/MotB, C-terminal domain; COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins.


ensembl_gene_id: S7S_13110
symbol: S7S_13110
gene_biotype: protein_coding
description:
  Flavodoxin reductase-like protein; COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1.


ensembl_gene_id: S7S_13135
symbol: S7S_13135
gene_biotype: protein_coding
description:
  Molybdopterin synthase sulfurylase MoeB; COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2.


ensembl_gene_id: S7S_13140
symbol: prmC
gene_biotype: protein_coding
description:
  N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.


ensembl_gene_id: S7S_13145
symbol: prfA
gene_biotype: protein_coding
description:
  Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.


ensembl_gene_id: S7S_13150
symbol: hemA
gene_biotype: protein_coding
description:
  glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).


ensembl_gene_id: S7S_13160
symbol: S7S_13160
gene_biotype: protein_coding
description:
  Molecular chaperone LolB; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.


ensembl_gene_id: S7S_13165
symbol: ispE
gene_biotype: protein_coding
description:
  4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.


ensembl_gene_id: S7S_13170
symbol: prs
gene_biotype: protein_coding
description:
  Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.


ensembl_gene_id: S7S_13175
symbol: rplY
gene_biotype: protein_coding
description:
  50S ribosomal protein L25/general stress protein Ctc; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.


ensembl_gene_id: S7S_13180
symbol: pth
gene_biotype: protein_coding
description:
  peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.


ensembl_gene_id: S7S_13190
symbol: ychF
gene_biotype: protein_coding
description:
  GTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.


ensembl_gene_id: S7S_13205
symbol: S7S_13205
gene_biotype: protein_coding
description:
  DEAD/DEAH box helicase domain-containing protein; COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster.


ensembl_gene_id: S7S_13225
symbol: S7S_13225
gene_biotype: protein_coding
description:
  COG2865 Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen.


ensembl_gene_id: S7S_13290
symbol: S7S_13290
gene_biotype: protein_coding
description:
  COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit.


ensembl_gene_id: S7S_13300
symbol: S7S_13300
gene_biotype: protein_coding
description:
  Putative periplasmic binding protein; COG2358 TRAP-type uncharacterized transport system, periplasmic component.


ensembl_gene_id: S7S_13310
symbol: S7S_13310
gene_biotype: protein_coding
description:
  Hypothetical protein; COG4666 TRAP-type uncharacterized transport system, fused permease components.


ensembl_gene_id: S7S_13335
symbol: S7S_13335
gene_biotype: protein_coding
description:
  ferredoxin--NAD(+) reductase FAD/NAD(P)-binding protein; COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases.


ensembl_gene_id: S7S_13375
symbol: S7S_13375
gene_biotype: protein_coding
description:
  Cytochrome c oxidase subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).


ensembl_gene_id: S7S_13380
symbol: S7S_13380
gene_biotype: protein_coding
description:
  Cytochrome c oxidase subunit I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.


ensembl_gene_id: S7S_13405
symbol: S7S_13405
gene_biotype: protein_coding
description:
  COG1999 Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems.


ensembl_gene_id: S7S_13415
symbol: cyoE
gene_biotype: protein_coding
description:
  Prenyltransferase family protein; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.


ensembl_gene_id: S7S_13455
symbol: S7S_13455
gene_biotype: protein_coding
description:
  Sodium solute transporter family protein; COG0591 Na+/proline symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: S7S_13470
symbol: S7S_13470
gene_biotype: protein_coding
description:
  PAS/PAC sensor(s)-containing diguanylate cyclase/phosphodiesterase; COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.


ensembl_gene_id: S7S_13480
symbol: S7S_13480
gene_biotype: protein_coding
description:
  COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.


ensembl_gene_id: S7S_13485
symbol: S7S_13485
gene_biotype: protein_coding
description:
  Short-chain dehydrogenase/reductase family protein; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: S7S_13495
symbol: rhlB
gene_biotype: protein_coding
description:
  ATP-dependent RNA helicase RhlB; DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. Belongs to the DEAD box helicase family. RhlB subfamily.


ensembl_gene_id: S7S_13505
symbol: S7S_13505
gene_biotype: protein_coding
description:
  PhoH family protein; COG1875 Predicted ATPase related to phosphate starvation-inducible protein PhoH.


ensembl_gene_id: S7S_13545
symbol: miaB
gene_biotype: protein_coding
description:
  (dimethylallyl)adenosine tRNA methylthiotransferase; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.


ensembl_gene_id: S7S_13555
symbol: S7S_13555
gene_biotype: protein_coding
description:
  Sulfate/thiosulfate transporter subunit; Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: S7S_13565
symbol: cysA
gene_biotype: protein_coding
description:
  Sulfate ABC transporter ATPase; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system.


ensembl_gene_id: S7S_13575
symbol: ybeY
gene_biotype: protein_coding
description:
  Hypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.


ensembl_gene_id: S7S_13595
symbol: lnt
gene_biotype: protein_coding
description:
  Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily.


ensembl_gene_id: S7S_13615
symbol: lptE
gene_biotype: protein_coding
description:
  Rare lipoprotein B; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane; Belongs to the LptE lipoprotein family.


ensembl_gene_id: S7S_13635
symbol: proA
gene_biotype: protein_coding
description:
  Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.


ensembl_gene_id: S7S_13640
symbol: nadD
gene_biotype: protein_coding
description:
  Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).


ensembl_gene_id: S7S_13645
symbol: rsfS
gene_biotype: protein_coding
description:
  Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.


ensembl_gene_id: S7S_13650
symbol: rlmH
gene_biotype: protein_coding
description:
  Ribosomal RNA large subunit methyltransferase H; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family.


ensembl_gene_id: S7S_13655
symbol: mrdA
gene_biotype: protein_coding
description:
  Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.


ensembl_gene_id: S7S_13660
symbol: mrdB
gene_biotype: protein_coding
description:
  Rod-shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.


ensembl_gene_id: S7S_13670
symbol: rlpA
gene_biotype: protein_coding
description:
  Lipoprotein, rare lipoprotein A family lipoprotein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.


ensembl_gene_id: S7S_13675
symbol: S7S_13675
gene_biotype: protein_coding
description:
  D-alanyl-D-alanine-carboxypeptidase; COG1686 D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family.


ensembl_gene_id: S7S_13690
symbol: lipB
gene_biotype: protein_coding
description:
  Octanoyltransferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.


ensembl_gene_id: S7S_13695
symbol: lipA
gene_biotype: protein_coding
description:
  Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.


ensembl_gene_id: S7S_13760
symbol: S7S_13760
gene_biotype: protein_coding
description:
  TonB family protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.


ensembl_gene_id: S7S_13770
symbol: cysA-2
gene_biotype: protein_coding
description:
  Sulfate/thiosulfate import ATP-binding protein cysA 2; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system.


ensembl_gene_id: S7S_13780
symbol: S7S_13780
gene_biotype: protein_coding
description:
  ABC-type sulfate/thiosulfate uptakesystem permease component 1 CysT; Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: S7S_13785
symbol: S7S_13785
gene_biotype: protein_coding
description:
  Sulfate ABC transporter substrate-binding protein; COG1613 ABC-type sulfate transport system, periplasmic component.


ensembl_gene_id: S7S_13810
symbol: ubiX
gene_biotype: protein_coding
description:
  Aromatic acid decarboxylase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family.


ensembl_gene_id: S7S_13820
symbol: mpl
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily.


ensembl_gene_id: S7S_13830
symbol: S7S_13830
gene_biotype: protein_coding
description:
  Formamidase regulatory protein FmdB; COG0086 DNA-directed RNA polymerase, beta' subunit/160 kD subunit.


ensembl_gene_id: S7S_13845
symbol: S7S_13845
gene_biotype: protein_coding
description:
  Urea ABC transporter ATP-binding protein UrtD; COG4674 Uncharacterized ABC-type transport system, ATPase component.


ensembl_gene_id: S7S_13850
symbol: S7S_13850
gene_biotype: protein_coding
description:
  Urea ABC transporter permease UrtC; COG4177 ABC-type branched-chain amino acid transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: S7S_13855
symbol: S7S_13855
gene_biotype: protein_coding
description:
  COG0559 Branched-chain amino acid ABC-type transport system, permease components; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: S7S_13860
symbol: S7S_13860
gene_biotype: protein_coding
description:
  Urea ABC transporter substrate-binding protein; COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component.


ensembl_gene_id: S7S_13870
symbol: S7S_13870
gene_biotype: protein_coding
description:
  LuxR family transcriptional regulator; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: S7S_13875
symbol: pfp
gene_biotype: protein_coding
description:
  6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.


ensembl_gene_id: S7S_13885
symbol: S7S_13885
gene_biotype: protein_coding
description:
  DEAD/DEAH box helicase; COG0513 Superfamily II DNA and RNA helicases; Belongs to the DEAD box helicase family.


ensembl_gene_id: S7S_13895
symbol: ppa
gene_biotype: protein_coding
description:
  Inorganic diphosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.


ensembl_gene_id: S7S_13925
symbol: aroQ
gene_biotype: protein_coding
description:
  3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.


ensembl_gene_id: S7S_13930
symbol: S7S_13930
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.


ensembl_gene_id: S7S_13935
symbol: S7S_13935
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.


ensembl_gene_id: S7S_13940
symbol: prmA
gene_biotype: protein_coding
description:
  50S ribosomal protein L11 methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family.


ensembl_gene_id: S7S_13950
symbol: dusB
gene_biotype: protein_coding
description:
  NifR3 family TIM-barrel protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily.


ensembl_gene_id: S7S_13955
symbol: S7S_13955
gene_biotype: protein_coding
description:
  Fis family transcriptional regulator; Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters; Belongs to the transcriptional regulatory Fis family.


ensembl_gene_id: S7S_13960
symbol: purH
gene_biotype: protein_coding
description:
  Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful).


ensembl_gene_id: S7S_13970
symbol: S7S_13970
gene_biotype: protein_coding
description:
  cAMP-dependent protein kinase regulatory chain; COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases.


ensembl_gene_id: S7S_13990
symbol: coq7
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6- methoxy-1,4-benzoquinol during ubiquinone biosynthesis.


ensembl_gene_id: S7S_14005
symbol: speD
gene_biotype: protein_coding
description:
  S-adenosylmethionine decarboxylase; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.


ensembl_gene_id: S7S_14020
symbol: S7S_14020
gene_biotype: protein_coding
description:
  DNA-binding transcriptional dual regulator Crp; COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases.


ensembl_gene_id: S7S_14025
symbol: S7S_14025
gene_biotype: protein_coding
description:
  Lysophospholipase-like protein; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: S7S_14040
symbol: S7S_14040
gene_biotype: protein_coding
description:
  TRAP dicarboxylate transporter- DctP subunit; COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component.


ensembl_gene_id: S7S_14050
symbol: S7S_14050
gene_biotype: protein_coding
description:
  TRAP transporter, DctM subunit subfamily protein; COG1593 TRAP-type C4-dicarboxylate transport system, large permease component.


ensembl_gene_id: S7S_14060
symbol: S7S_14060
gene_biotype: protein_coding
description:
  Class II aldolase and adducin N-terminal domain-containing protein 3; COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases.


ensembl_gene_id: S7S_14125
symbol: S7S_14125
gene_biotype: protein_coding
description:
  COG4941 Predicted RNA polymerase sigma factor containing a TPR repeat domain; Belongs to the sigma-70 factor family.


ensembl_gene_id: S7S_14155
symbol: trpD
gene_biotype: protein_coding
description:
  Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).


ensembl_gene_id: S7S_14180
symbol: S7S_14180
gene_biotype: protein_coding
description:
  Two-component system heavy metal sensor histidine kinase; Member of a two-component regulatory system.


ensembl_gene_id: S7S_14185
symbol: S7S_14185
gene_biotype: protein_coding
description:
  Two-component system copper resistance phosphate regulon response regulator; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: S7S_14530
symbol: trpE
gene_biotype: protein_coding
description:
  Anthranilate synthase, component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concent [...]


ensembl_gene_id: S7S_14560
symbol: fliA
gene_biotype: protein_coding
description:
  RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily.


ensembl_gene_id: S7S_14570
symbol: flhA
gene_biotype: protein_coding
description:
  Flagellar biosynthesis protein A; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.


ensembl_gene_id: S7S_14580
symbol: flhB
gene_biotype: protein_coding
description:
  Flagellar biosynthesis protein FlhB; Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the type III secretion exporter family.


ensembl_gene_id: S7S_14585
symbol: S7S_14585
gene_biotype: protein_coding
description:
  Chemotaxis regulator CheZ; Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).


ensembl_gene_id: S7S_14600
symbol: cheB
gene_biotype: protein_coding
description:
  Chemotaxis-specific protein-glutamate methyltransferase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.


ensembl_gene_id: S7S_14605
symbol: S7S_14605
gene_biotype: protein_coding
description:
  Chemotaxis protein CheR; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.


ensembl_gene_id: S7S_14635
symbol: flhC
gene_biotype: protein_coding
description:
  Transcriptional activator FlhC; Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhC family.


ensembl_gene_id: S7S_14640
symbol: flhD
gene_biotype: protein_coding
description:
  Putative flagellar transcriptional activator transcription regulator protein; Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhD family.


ensembl_gene_id: S7S_14645
symbol: S7S_14645
gene_biotype: protein_coding
description:
  Flagellar protein FhlB-like protein; COG2257 Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB.


ensembl_gene_id: S7S_14665
symbol: S7S_14665
gene_biotype: protein_coding
description:
  Flagellar hook-associated 2-like protein; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.


ensembl_gene_id: S7S_14675
symbol: S7S_14675
gene_biotype: protein_coding
description:
  Flagellin; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.


ensembl_gene_id: S7S_14695
symbol: S7S_14695
gene_biotype: protein_coding
description:
  Flagellar MS-ring protein; The M ring may be actively involved in energy transduction. Belongs to the FliF family.


ensembl_gene_id: S7S_14700
symbol: S7S_14700
gene_biotype: protein_coding
description:
  Flagellar motor switch protein G; FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.


ensembl_gene_id: S7S_14725
symbol: S7S_14725
gene_biotype: protein_coding
description:
  Flagellar basal body-associated protein FliL; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.


ensembl_gene_id: S7S_14730
symbol: S7S_14730
gene_biotype: protein_coding
description:
  Flagellar motor switch protein FliM; FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.


ensembl_gene_id: S7S_14735
symbol: S7S_14735
gene_biotype: protein_coding
description:
  Flagellar motor switch protein; FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliN/MopA/SpaO family.


ensembl_gene_id: S7S_14745
symbol: fliP
gene_biotype: protein_coding
description:
  Flagellar biosynthetic protein; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family.


ensembl_gene_id: S7S_14750
symbol: fliQ
gene_biotype: protein_coding
description:
  Flagellar biosynthetic fliq transmembrane protein; Role in flagellar biosynthesis. Belongs to the FliQ/MopD/SpaQ family.


ensembl_gene_id: S7S_14755
symbol: S7S_14755
gene_biotype: protein_coding
description:
  Flagellar biosynthetic protein FliR; Role in flagellar biosynthesis. Belongs to the FliR/MopE/SpaR family.


ensembl_gene_id: S7S_14765
symbol: S7S_14765
gene_biotype: protein_coding
description:
  Plasmid stability protein StbB; COG1487 Predicted nucleic acid-binding protein, contains PIN domain.


ensembl_gene_id: S7S_14785
symbol: flgI
gene_biotype: protein_coding
description:
  Flagellar basal body P-ring protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.


ensembl_gene_id: S7S_14790
symbol: flgH
gene_biotype: protein_coding
description:
  Flagellar basal body L-ring protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.


ensembl_gene_id: S7S_14810
symbol: flgD
gene_biotype: protein_coding
description:
  Flagellar basal body rod modification protein; Required for flagellar hook formation. May act as a scaffolding protein.


ensembl_gene_id: S7S_14820
symbol: S7S_14820
gene_biotype: protein_coding
description:
  Flagellar basal-body rod protein FlgB; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.


ensembl_gene_id: S7S_14825
symbol: S7S_14825
gene_biotype: protein_coding
description:
  Flagellar basal body P-ring biosynthesis protein FlgA; Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P- ring assembly; Belongs to the FlgA family.


ensembl_gene_id: S7S_14845
symbol: S7S_14845
gene_biotype: protein_coding
description:
  Oxidoreductase, FAD/FMN-binding superfamily protein; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family.


ensembl_gene_id: S7S_14865
symbol: S7S_14865
gene_biotype: protein_coding
description:
  COG0843 Heme/copper-type cytochrome/quinol oxidases, subunit 1; Belongs to the heme-copper respiratory oxidase family.


ensembl_gene_id: S7S_14900
symbol: S7S_14900
gene_biotype: protein_coding
description:
  Nucleotidyltransferase family protein; COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon).


ensembl_gene_id: S7S_14910
symbol: lptD
gene_biotype: protein_coding
description:
  Hypothetical protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.


ensembl_gene_id: S7S_14915
symbol: surA
gene_biotype: protein_coding
description:
  Survival protein SurA; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.


ensembl_gene_id: S7S_14920
symbol: pdxA
gene_biotype: protein_coding
description:
  Pyridoxal phosphate biosynthetic protein PdxA; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).


ensembl_gene_id: S7S_14925
symbol: rsmA
gene_biotype: protein_coding
description:
  Ribosomal RNA small subunit methyltransferase A; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.


ensembl_gene_id: S7S_14935
symbol: apaH
gene_biotype: protein_coding
description:
  Diadenosine tetraphosphatase; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family.


ensembl_gene_id: S7S_14970
symbol: cca
gene_biotype: protein_coding
description:
  tRNA cytidylyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.


ensembl_gene_id: S7S_14975
symbol: S7S_14975
gene_biotype: protein_coding
description:
  Dehydrogenase/reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: S7S_15000
symbol: S7S_15000
gene_biotype: protein_coding
description:
  7, 8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase.


ensembl_gene_id: S7S_15005
symbol: S7S_15005
gene_biotype: protein_coding
description:
  Dihydroneopterin aldolase family protein; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.


ensembl_gene_id: S7S_15010
symbol: plsY
gene_biotype: protein_coding
description:
  Glycerol-3-phosphate acyltransferase; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.


ensembl_gene_id: S7S_15015
symbol: tsaD
gene_biotype: protein_coding
description:
  Glycoprotease family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.


ensembl_gene_id: S7S_15030
symbol: dnaG
gene_biotype: protein_coding
description:
  DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.


ensembl_gene_id: S7S_15035
symbol: rpoD
gene_biotype: protein_coding
description:
  RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.


ensembl_gene_id: S7S_15085
symbol: S7S_15085
gene_biotype: protein_coding
description:
  Hypothetical protein; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.


ensembl_gene_id: S7S_15100
symbol: S7S_15100
gene_biotype: protein_coding
description:
  Fatty acyl-CoA reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: S7S_15145
symbol: S7S_15145
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component.


ensembl_gene_id: S7S_15195
symbol: S7S_15195
gene_biotype: protein_coding
description:
  Outer membrane phospholipase A; Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities. Belongs to the phospholipase A1 family.


ensembl_gene_id: S7S_15255
symbol: S7S_15255
gene_biotype: protein_coding
description:
  Membrane protein; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. Belongs to the ApbE family.


ensembl_gene_id: S7S_15350
symbol: thrS
gene_biotype: protein_coding
description:
  Threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).


ensembl_gene_id: S7S_15355
symbol: hisI
gene_biotype: protein_coding
description:
  phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.


ensembl_gene_id: S7S_15370
symbol: S7S_15370
gene_biotype: protein_coding
description:
  Alpha-hemolysin; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family.


ensembl_gene_id: S7S_15410
symbol: ectA
gene_biotype: protein_coding
description:
  DABA acetyltransferase; Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A.


ensembl_gene_id: S7S_15415
symbol: S7S_15415
gene_biotype: protein_coding
description:
  Diaminobutyrate--2-oxoglutarate aminotransferase; Catalyzes reversively the conversion of L-aspartate beta- semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: S7S_15420
symbol: ectC
gene_biotype: protein_coding
description:
  L-ectoine synthase; Catalyzes the circularization of gamma-N-acetyl-alpha,gamma- diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4- pyrimidine carboxylic acid), which is an excellent osmoprotectant.


ensembl_gene_id: S7S_15440
symbol: acsA
gene_biotype: protein_coding
description:
  Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.


ensembl_gene_id: S7S_15445
symbol: S7S_15445
gene_biotype: protein_coding
description:
  Transcriptional regulator DegU; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: S7S_15475
symbol: S7S_15475
gene_biotype: protein_coding
description:
  Cyclic nucleotide-binding domain-containing protein; COG2905 Predicted signal-transduction protein containing cAMP-binding and CBS domains.


ensembl_gene_id: S7S_15490
symbol: dusC
gene_biotype: protein_coding
description:
  Dihydrouridine synthase (Dus) superfamily protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs. Belongs to the Dus family. DusC subfamily.


ensembl_gene_id: S7S_15500
symbol: xseB
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.


ensembl_gene_id: S7S_15510
symbol: dxs
gene_biotype: protein_coding
description:
  Deoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.


ensembl_gene_id: S7S_15530
symbol: S7S_15530
gene_biotype: protein_coding
description:
  C4-dicarboxylate transporter/malic acid transport protein; COG1275 Tellurite resistance protein and related permeases.


ensembl_gene_id: S7S_15540
symbol: S7S_15540
gene_biotype: protein_coding
description:
  Phosphatidylglycerophosphatase A; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).


ensembl_gene_id: S7S_15545
symbol: thiL
gene_biotype: protein_coding
description:
  Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.


ensembl_gene_id: S7S_15550
symbol: nusB
gene_biotype: protein_coding
description:
  Transcriptional terminator nusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.


ensembl_gene_id: S7S_15555
symbol: ribH
gene_biotype: protein_coding
description:
  6,7-dimethyl-8-ribityllumazine synthase 2; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family.


ensembl_gene_id: S7S_15565
symbol: S7S_15565
gene_biotype: protein_coding
description:
  Glucan biosynthesis protein D; Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).


ensembl_gene_id: S7S_15575
symbol: ribB
gene_biotype: protein_coding
description:
  Bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II-like protein; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.


ensembl_gene_id: S7S_15585
symbol: S7S_15585
gene_biotype: protein_coding
description:
  (S)-2-hydroxy-fatty-acid dehydrogenase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.


ensembl_gene_id: S7S_15590
symbol: nrdR
gene_biotype: protein_coding
description:
  Transcriptional regulator; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.


ensembl_gene_id: S7S_15595
symbol: glyA
gene_biotype: protein_coding
description:
  Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.


ensembl_gene_id: S7S_15610
symbol: S7S_15610
gene_biotype: protein_coding
description:
  Hypothetical protein; Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second-messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a possible effector protein.


ensembl_gene_id: S7S_15625
symbol: radA
gene_biotype: protein_coding
description:
  DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.


ensembl_gene_id: S7S_15630
symbol: S7S_15630
gene_biotype: protein_coding
description:
  Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.


ensembl_gene_id: S7S_15635
symbol: S7S_15635
gene_biotype: protein_coding
description:
  DNA helicase, DnaB type; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily.


ensembl_gene_id: S7S_15670
symbol: rpsR
gene_biotype: protein_coding
description:
  30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.


ensembl_gene_id: S7S_15695
symbol: S7S_15695
gene_biotype: protein_coding
description:
  COG0566 rRNA methylases; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.


ensembl_gene_id: S7S_15700
symbol: rnr
gene_biotype: protein_coding
description:
  Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.


ensembl_gene_id: S7S_15720
symbol: purA
gene_biotype: protein_coding
description:
  Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.


ensembl_gene_id: S7S_15725
symbol: hisZ
gene_biotype: protein_coding
description:
  ATP phosphoribosyl transferase regulatory subunit; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.


ensembl_gene_id: S7S_15745
symbol: hflX
gene_biotype: protein_coding
description:
  Protease GTPase subunit; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.


ensembl_gene_id: S7S_15750
symbol: hfq
gene_biotype: protein_coding
description:
  Host factor Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.


ensembl_gene_id: S7S_15755
symbol: miaA
gene_biotype: protein_coding
description:
  tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.


ensembl_gene_id: S7S_15765
symbol: mutL
gene_biotype: protein_coding
description:
  DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.


ensembl_gene_id: S7S_15780
symbol: nnrE
gene_biotype: protein_coding
description:
  Carbohydrate kinase family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.  Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repa [...]


ensembl_gene_id: S7S_15785
symbol: queG
gene_biotype: protein_coding
description:
  (Fe-S)-binding protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family.


ensembl_gene_id: S7S_15810
symbol: orn
gene_biotype: protein_coding
description:
  Oligoribonuclease; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family.


ensembl_gene_id: S7S_15820
symbol: rsgA
gene_biotype: protein_coding
description:
  GTPase RsgA; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.


ensembl_gene_id: S7S_15830
symbol: psd
gene_biotype: protein_coding
description:
  Phosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).


ensembl_gene_id: S7S_15835
symbol: S7S_15835
gene_biotype: protein_coding
description:
  rimK domain-containing protein ATP-grasp; COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase).


ensembl_gene_id: S7S_15845
symbol: S7S_15845
gene_biotype: protein_coding
description:
  Phosphoserine phosphatase SerB:HAD-superfamily hydrolase, subfamily IB; COG3830 ACT domain-containing protein.


ensembl_gene_id: S7S_15865
symbol: efp
gene_biotype: protein_coding
description:
  Translation elongation factor P; Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation; Belongs to the elongation factor P family.


ensembl_gene_id: S7S_15875
symbol: S7S_15875
gene_biotype: protein_coding
description:
  Extracellular ligand-binding receptor; COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component.


ensembl_gene_id: S7S_15905
symbol: dksA
gene_biotype: protein_coding
description:
  DnaK transcriptional regulator DksA; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.


ensembl_gene_id: S7S_15910
symbol: S7S_15910
gene_biotype: protein_coding
description:
  COG0008 Glutamyl- and glutaminyl-tRNA synthetases; Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: S7S_15930
symbol: pcnB
gene_biotype: protein_coding
description:
  poly(A) polymerase; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control. Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.


ensembl_gene_id: S7S_15935
symbol: S7S_15935
gene_biotype: protein_coding
description:
  2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase.


ensembl_gene_id: S7S_15945
symbol: panB
gene_biotype: protein_coding
description:
  3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.


ensembl_gene_id: S7S_15950
symbol: panC
gene_biotype: protein_coding
description:
  Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.


ensembl_gene_id: S7S_15955
symbol: panD
gene_biotype: protein_coding
description:
  Aspartate alpha-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.


ensembl_gene_id: S7S_15960
symbol: acsA-2
gene_biotype: protein_coding
description:
  Acetyl-coenzyme A synthetase 2; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.


ensembl_gene_id: S7S_16010
symbol: S7S_16010
gene_biotype: protein_coding
description:
  Transglutaminase domain-containing protein; COG1305 Transglutaminase-like enzymes, putative cysteine proteases.


ensembl_gene_id: S7S_16045
symbol: S7S_16045
gene_biotype: protein_coding
description:
  Metallophosphoesterase; COG4632 Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase.


ensembl_gene_id: S7S_16165
symbol: S7S_16165
gene_biotype: protein_coding
description:
  NAD dependent epimerase/dehydratase family protein; COG0451 Nucleoside-diphosphate-sugar epimerases.


ensembl_gene_id: S7S_16180
symbol: S7S_16180
gene_biotype: protein_coding
description:
  Linear amide C-N hydrolase, choloylglycine hydrolase family protein; COG3049 Penicillin V acylase and related amidases.


ensembl_gene_id: S7S_16210
symbol: def-2
gene_biotype: protein_coding
description:
  Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.


ensembl_gene_id: S7S_16225
symbol: S7S_16225
gene_biotype: protein_coding
description:
  Sigma-24 (FecI); COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family.


ensembl_gene_id: S7S_16230
symbol: S7S_16230
gene_biotype: protein_coding
description:
  Alkylhydroperoxidase; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.


ensembl_gene_id: S7S_16240
symbol: S7S_16240
gene_biotype: protein_coding
description:
  TonB-dependent siderophore receptor subfamily protein; COG1629 Outer membrane receptor proteins, mostly Fe transport.


ensembl_gene_id: S7S_16270
symbol: purE
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazole carboxylase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).


ensembl_gene_id: S7S_16275
symbol: S7S_16275
gene_biotype: protein_coding
description:
  ATP-grasp domain-containing protein; COG0026 Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase).


ensembl_gene_id: S7S_16295
symbol: S7S_16295
gene_biotype: protein_coding
description:
  Eukaryotic hydroxysteroid (17-beta) dehydrogenase 4; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: S7S_16340
symbol: S7S_16340
gene_biotype: protein_coding
description:
  Substrate-binding protein, ABC-type oligopeptide transporter; COG0747 ABC-type dipeptide transport system, periplasmic component.


ensembl_gene_id: S7S_16355
symbol: S7S_16355
gene_biotype: protein_coding
description:
  Oligopeptide/dipeptide ABC transporter ATP-binding protein-like protein; COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase; Belongs to the ABC transporter superfamily.


ensembl_gene_id: S7S_16470
symbol: pnp
gene_biotype: protein_coding
description:
  Polynucleotide phosphorylase/polyadenylase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.


ensembl_gene_id: S7S_16475
symbol: rpsO
gene_biotype: protein_coding
description:
  30S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.


ensembl_gene_id: S7S_16480
symbol: truB
gene_biotype: protein_coding
description:
  Pseudouridylate synthase; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.


ensembl_gene_id: S7S_16485
symbol: rbfA
gene_biotype: protein_coding
description:
  Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.


ensembl_gene_id: S7S_16490
symbol: infB
gene_biotype: protein_coding
description:
  Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.


ensembl_gene_id: S7S_16495
symbol: nusA
gene_biotype: protein_coding
description:
  Transcription elongation factor; Participates in both transcription termination and antitermination.


ensembl_gene_id: S7S_16500
symbol: rimP
gene_biotype: protein_coding
description:
  Hypothetical protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.


ensembl_gene_id: S7S_16505
symbol: secG
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.


ensembl_gene_id: S7S_16510
symbol: tpiA
gene_biotype: protein_coding
description:
  Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.


ensembl_gene_id: S7S_16515
symbol: glmM
gene_biotype: protein_coding
description:
  Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.


ensembl_gene_id: S7S_16525
symbol: ftsH
gene_biotype: protein_coding
description:
  Cell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family.  In the central section; belongs to the AAA ATPase family.


ensembl_gene_id: S7S_16530
symbol: rlmE
gene_biotype: protein_coding
description:
  Ribosomal RNA large subunit methyltransferase E; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.


ensembl_gene_id: S7S_16540
symbol: greA
gene_biotype: protein_coding
description:
  Transcription elongation factor greA 1; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.


ensembl_gene_id: S7S_16555
symbol: dapB
gene_biotype: protein_coding
description:
  Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.


ensembl_gene_id: S7S_16590
symbol: dnaJ
gene_biotype: protein_coding
description:
  Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]


ensembl_gene_id: S7S_16600
symbol: grpE
gene_biotype: protein_coding
description:
  Protein grpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]


ensembl_gene_id: S7S_16605
symbol: hrcA
gene_biotype: protein_coding
description:
  Heat-inducible transcription repressor hrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons.


ensembl_gene_id: S7S_16615
symbol: fur
gene_biotype: protein_coding
description:
  Fur family transcriptional regulator; COG0735 Fe2+/Zn2+ uptake regulation proteins; Belongs to the Fur family.


ensembl_gene_id: S7S_16620
symbol: bamE
gene_biotype: protein_coding
description:
  Outer membrane lipoprotein OmlA; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: S7S_16630
symbol: S7S_16630
gene_biotype: protein_coding
description:
  COG0733 Na+-dependent transporters of the SNF family; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.


ensembl_gene_id: S7S_16635
symbol: smpB
gene_biotype: protein_coding
description:
  SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]


ensembl_gene_id: S7S_16685
symbol: S7S_16685
gene_biotype: protein_coding
description:
  XRE family transcriptional regulator; COG5499 Predicted transcription regulator containing HTH domain.


ensembl_gene_id: S7S_16710
symbol: S7S_16710
gene_biotype: protein_coding
description:
  Lipoprotein release ABC transporter permease; COG0577 ABC-type antimicrobial peptide transport system, permease component.


ensembl_gene_id: S7S_16730
symbol: mtgA
gene_biotype: protein_coding
description:
  Monofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family.


ensembl_gene_id: S7S_16750
symbol: cobQ
gene_biotype: protein_coding
description:
  Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.


ensembl_gene_id: S7S_16760
symbol: S7S_16760
gene_biotype: protein_coding
description:
  cob(I)alamin adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.


ensembl_gene_id: S7S_16770
symbol: S7S_16770
gene_biotype: protein_coding
description:
  Transporter permease; COG0609 ABC-type Fe3+-siderophore transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: S7S_16790
symbol: S7S_16790
gene_biotype: protein_coding
description:
  Aminotransferase; COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase.


ensembl_gene_id: S7S_16795
symbol: cobD
gene_biotype: protein_coding
description:
  Cobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.


ensembl_gene_id: S7S_16800
symbol: cobT
gene_biotype: protein_coding
description:
  Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).


ensembl_gene_id: S7S_16810
symbol: cobS
gene_biotype: protein_coding
description:
  Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.


ensembl_gene_id: S7S_16820
symbol: S7S_16820
gene_biotype: protein_coding
description:
  Cobinamide kinase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.


ensembl_gene_id: S7S_16825
symbol: S7S_16825
gene_biotype: protein_coding
description:
  Cation transport regulator protein; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.


ensembl_gene_id: S7S_16850
symbol: S7S_16850
gene_biotype: protein_coding
description:
  Molybdopterin biosynthesis protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.


ensembl_gene_id: S7S_16855
symbol: S7S_16855
gene_biotype: protein_coding
description:
  Molybdenum cofactor biosynthesis protein B; May be involved in the biosynthesis of molybdopterin. Belongs to the MoaB/Mog family.


ensembl_gene_id: S7S_16870
symbol: S7S_16870
gene_biotype: protein_coding
description:
  Fic family protein; Adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins.


ensembl_gene_id: S7S_16905
symbol: S7S_16905
gene_biotype: protein_coding
description:
  D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain protein; COG1052 Lactate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: S7S_16920
symbol: S7S_16920
gene_biotype: protein_coding
description:
  Arginine decarboxylase; Catalyzes the biosynthesis of agmatine from arginine. Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.


ensembl_gene_id: S7S_16925
symbol: speE
gene_biotype: protein_coding
description:
  Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.


ensembl_gene_id: S7S_16990
symbol: S7S_16990
gene_biotype: protein_coding
description:
  Alpha/beta fold hydrolase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: S7S_17005
symbol: S7S_17005
gene_biotype: protein_coding
description:
  methylated-DNA--protein-cysteine methyltransferase; COG2207 AraC-type DNA-binding domain-containing proteins.


ensembl_gene_id: S7S_17050
symbol: S7S_17050
gene_biotype: protein_coding
description:
  Short chain dehydrogenase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: S7S_17065
symbol: S7S_17065
gene_biotype: protein_coding
description:
  P2-like signal transmitter protein; COG0347 Nitrogen regulatory protein PII; Belongs to the P(II) protein family.


ensembl_gene_id: S7S_17095
symbol: S7S_17095
gene_biotype: protein_coding
description:
  NAD dependent epimerase/dehydratase family protein; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: S7S_17100
symbol: rep
gene_biotype: protein_coding
description:
  UvrD/REP helicase subfamily protein; Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.


ensembl_gene_id: S7S_17200
symbol: mltF-2
gene_biotype: protein_coding
description:
  Transglycosylase; Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.


ensembl_gene_id: S7S_17210
symbol: S7S_17210
gene_biotype: protein_coding
description:
  ABC transporter transmembrane protein; COG0842 ABC-type multidrug transport system, permease component.


ensembl_gene_id: S7S_17305
symbol: S7S_17305
gene_biotype: protein_coding
description:
  O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase subfamily protein; COG2873 O-acetylhomoserine sulfhydrylase.


ensembl_gene_id: S7S_17355
symbol: mscL
gene_biotype: protein_coding
description:
  Large-conductance mechanosensitive channel; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.


ensembl_gene_id: S7S_17360
symbol: tpx
gene_biotype: protein_coding
description:
  Redoxin domain protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily.


ensembl_gene_id: S7S_17430
symbol: msrA-2
gene_biotype: protein_coding
description:
  Peptide methionine sulfoxide reductase family protein; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.


ensembl_gene_id: S7S_17585
symbol: recD
gene_biotype: protein_coding
description:
  Exonuclease V subunit alpha; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Hol [...]


ensembl_gene_id: S7S_17590
symbol: recB
gene_biotype: protein_coding
description:
  ATP-dependent exonuclease V subunit beta; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination an [...]


ensembl_gene_id: S7S_17595
symbol: recC
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease V subunit gamma; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and re [...]


ensembl_gene_id: S7S_17620
symbol: engB
gene_biotype: protein_coding
description:
  GTP-binding protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.


ensembl_gene_id: S7S_17630
symbol: polA
gene_biotype: protein_coding
description:
  DNA polymerase I superfamily protein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.


ensembl_gene_id: S7S_17645
symbol: thrB
gene_biotype: protein_coding
description:
  COG2334 Putative homoserine kinase type II (protein kinase fold); Belongs to the pseudomonas-type ThrB family.


ensembl_gene_id: S7S_17660
symbol: S7S_17660
gene_biotype: protein_coding
description:
  High-affinity zinc uptake system protein znuA; COG4531 ABC-type Zn2+ transport system, periplasmic component/surface adhesin.


ensembl_gene_id: S7S_17665
symbol: znuC
gene_biotype: protein_coding
description:
  Zinc transport protein ATPase; Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family.


ensembl_gene_id: S7S_17670
symbol: S7S_17670
gene_biotype: protein_coding
description:
  High-affinity zinc uptake system membrane protein ZnuB; COG1108 ABC-type Mn2+/Zn2+ transport systems, permease components.


ensembl_gene_id: S7S_17715
symbol: S7S_17715
gene_biotype: protein_coding
description:
  Pyridine nucleotide-disulfide oxidoreductase; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Belongs to the FAD-dependent oxidoreductase family.


ensembl_gene_id: S7S_17725
symbol: ubiC
gene_biotype: protein_coding
description:
  Chorismate lyase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family.


ensembl_gene_id: S7S_17730
symbol: ubiA
gene_biotype: protein_coding
description:
  4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.


ensembl_gene_id: S7S_17735
symbol: S7S_17735
gene_biotype: protein_coding
description:
  Phosphate regulon transcriptional regulatory protein phoB; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: S7S_17775
symbol: S7S_17775
gene_biotype: protein_coding
description:
  Arsenate reductase; COG0394 Protein-tyrosine-phosphatase; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.


ensembl_gene_id: S7S_17790
symbol: pstB
gene_biotype: protein_coding
description:
  Phosphate transporter ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.


ensembl_gene_id: S7S_17800
symbol: S7S_17800
gene_biotype: protein_coding
description:
  Phosphate ABC transporter permease; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: S7S_17815
symbol: S7S_17815
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain.


ensembl_gene_id: S7S_17820
symbol: metX
gene_biotype: protein_coding
description:
  Homoserine O-acetyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.


ensembl_gene_id: S7S_17830
symbol: S7S_17830
gene_biotype: protein_coding
description:
  Nucleoside-triphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.


ensembl_gene_id: S7S_17840
symbol: S7S_17840
gene_biotype: protein_coding
description:
  Coproporphyrinogen oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.


ensembl_gene_id: S7S_17855
symbol: S7S_17855
gene_biotype: protein_coding
description:
  RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family protein; COG0841 Cation/multidrug efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: S7S_17860
symbol: bioA
gene_biotype: protein_coding
description:
  Adenosylmethionine--8-amino-7-oxononanoate transaminase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.


ensembl_gene_id: S7S_17865
symbol: S7S_17865
gene_biotype: protein_coding
description:
  Hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.


ensembl_gene_id: S7S_17900
symbol: S7S_17900
gene_biotype: protein_coding
description:
  Lipid A biosynthesis acyltransferase superfamily protein; COG1560 Lauroyl/myristoyl acyltransferase.


ensembl_gene_id: S7S_17915
symbol: S7S_17915
gene_biotype: protein_coding
description:
  Protein-glutamate methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.


ensembl_gene_id: S7S_17920
symbol: S7S_17920
gene_biotype: protein_coding
description:
  Two-component hybrid chemotactic sensor and regulator; COG0643 Chemotaxis protein histidine kinase and related kinases.


ensembl_gene_id: S7S_17950
symbol: gshB
gene_biotype: protein_coding
description:
  COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase); Belongs to the prokaryotic GSH synthase family.


ensembl_gene_id: S7S_17960
symbol: S7S_17960
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1678 Putative transcriptional regulator; Belongs to the UPF0301 (AlgH) family.


ensembl_gene_id: S7S_17965
symbol: S7S_17965
gene_biotype: protein_coding
description:
  Endonuclease, Holliday junction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family.


ensembl_gene_id: S7S_17970
symbol: S7S_17970
gene_biotype: protein_coding
description:
  Transcriptional regulator PyrR; COG2065 Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase.


ensembl_gene_id: S7S_17975
symbol: pyrB
gene_biotype: protein_coding
description:
  COG0540 Aspartate carbamoyltransferase, catalytic chain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.


ensembl_gene_id: S7S_17980
symbol: S7S_17980
gene_biotype: protein_coding
description:
  Dihydroorotase, multifunctional complex type; COG0044 Dihydroorotase and related cyclic amidohydrolases.


ensembl_gene_id: S7S_18025
symbol: S7S_18025
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family protein; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: S7S_18055
symbol: S7S_18055
gene_biotype: protein_coding
description:
  Hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.


ensembl_gene_id: S7S_18060
symbol: proC
gene_biotype: protein_coding
description:
  Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.


ensembl_gene_id: S7S_18100
symbol: S7S_18100
gene_biotype: protein_coding
description:
  Glycine cleavage system transcriptional activator; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: S7S_18115
symbol: S7S_18115
gene_biotype: protein_coding
description:
  RND efflux transporter, permease protein; COG0841 Cation/multidrug efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: S7S_18120
symbol: S7S_18120
gene_biotype: protein_coding
description:
  Multidrug RND efflux transporter, permease protein MdtB; COG0841 Cation/multidrug efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: S7S_18205
symbol: S7S_18205
gene_biotype: protein_coding
description:
  Filamentous hemagglutinin-like protein; COG3210 Large exoproteins involved in heme utilization or adhesion.


ensembl_gene_id: S7S_18215
symbol: S7S_18215
gene_biotype: protein_coding
description:
  Binding protein component of ABC transporter; Part of the ABC transporter complex PstSACB involved in phosphate import; Belongs to the PstS family.


ensembl_gene_id: S7S_18225
symbol: glmS
gene_biotype: protein_coding
description:
  Glucosamine 6-phosphate synthase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.


ensembl_gene_id: S7S_18230
symbol: glmU
gene_biotype: protein_coding
description:
  Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.


ensembl_gene_id: S7S_18235
symbol: atpC
gene_biotype: protein_coding
description:
  ATP synthase subunit epsilon; Produces ATP from ADP in the presence of a proton gradient across the membrane.


ensembl_gene_id: S7S_18240
symbol: atpD
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.


ensembl_gene_id: S7S_18245
symbol: atpG
gene_biotype: protein_coding
description:
  ATP synthase subunit gamma; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.


ensembl_gene_id: S7S_18250
symbol: atpA
gene_biotype: protein_coding
description:
  ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.


ensembl_gene_id: S7S_18255
symbol: atpH
gene_biotype: protein_coding
description:
  ATP synthase subunit delta; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.


ensembl_gene_id: S7S_18260
symbol: atpF
gene_biotype: protein_coding
description:
  ATP synthase subunit b; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family.


ensembl_gene_id: S7S_18265
symbol: atpE
gene_biotype: protein_coding
description:
  ATP synthase subunit c 1; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.


ensembl_gene_id: S7S_18270
symbol: atpB
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit A; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family.


ensembl_gene_id: S7S_18340
symbol: S7S_18340
gene_biotype: protein_coding
description:
  Transcriptional regulator LysR family protein; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: S7S_18345
symbol: S7S_18345
gene_biotype: protein_coding
description:
  ParB-like nuclease domain family protein; COG1475 Predicted transcriptional regulators; Belongs to the ParB family.


ensembl_gene_id: S7S_18355
symbol: rsmG
gene_biotype: protein_coding
description:
  Methyltransferase GidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.


ensembl_gene_id: S7S_18360
symbol: mnmG
gene_biotype: protein_coding
description:
  tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family.


ensembl_gene_id: S7S_18365
symbol: S7S_18365
gene_biotype: protein_coding
description:
  Sodium/hydrogen exchanger family protein; COG3263 NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain.


ensembl_gene_id: S7S_18430
symbol: rapA
gene_biotype: protein_coding
description:
  ATP-dependent helicase HepA; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily.


ensembl_gene_id: S7S_18455
symbol: S7S_18455
gene_biotype: protein_coding
description:
  COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.


ensembl_gene_id: S7S_18480
symbol: fumC
gene_biotype: protein_coding
description:
  Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.


ensembl_gene_id: S7S_18555
symbol: mnmE
gene_biotype: protein_coding
description:
  tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.


ensembl_gene_id: S7S_18560
symbol: yidC
gene_biotype: protein_coding
description:
  Hypothetical protein; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.


ensembl_gene_id: S7S_18565
symbol: rnpA
gene_biotype: protein_coding
description:
  Ribonuclease P, protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.


