# geneInfo

ensembl_gene_id: DB31_0018
symbol: hflX
gene_biotype: protein_coding
description:
  GTP-binding protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.


ensembl_gene_id: DB31_0046
symbol: fliQ
gene_biotype: protein_coding
description:
  Flagellar biosynthesis protein FliQ; Role in flagellar biosynthesis. Belongs to the FliQ/MopD/SpaQ family.


ensembl_gene_id: DB31_0077
symbol: DB31_0077
gene_biotype: protein_coding
description:
  Methylated-DNA--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.


ensembl_gene_id: DB31_0092
symbol: DB31_0092
gene_biotype: protein_coding
description:
  Ribosomal large subunit pseudouridine synthase B; Belongs to the pseudouridine synthase RsuA family.


ensembl_gene_id: DB31_0119
symbol: DB31_0119
gene_biotype: protein_coding
description:
  Oxidoreductase, short chain dehydrogenase/reductase family protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: DB31_0129
symbol: fusA
gene_biotype: protein_coding
description:
  Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...]


ensembl_gene_id: DB31_0147
symbol: DB31_0147
gene_biotype: protein_coding
description:
  Proton/glutamate symport protein; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: DB31_0164
symbol: DB31_0164
gene_biotype: protein_coding
description:
  Excinuclease ABC subunit A, dimeric form; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.


ensembl_gene_id: DB31_0177
symbol: DB31_0177
gene_biotype: protein_coding
description:
  Macrolide-specific efflux protein MacA; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: DB31_0196
symbol: DB31_0196
gene_biotype: protein_coding
description:
  3-oxoacyl-[acyl-carrier protein] reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: DB31_0197
symbol: DB31_0197
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family protein; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: DB31_0231
symbol: DB31_0231
gene_biotype: protein_coding
description:
  Putative RND efflux membrane fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: DB31_0232
symbol: DB31_0232
gene_biotype: protein_coding
description:
  Cobalt-zinc-cadmium resistance protein CzcA; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: DB31_0269
symbol: DB31_0269
gene_biotype: protein_coding
description:
  Ferric siderophore transport system, periplasmic binding protein TonB; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.


ensembl_gene_id: DB31_0307
symbol: cysH
gene_biotype: protein_coding
description:
  Phosphoadenylyl-sulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.


ensembl_gene_id: DB31_0311
symbol: DB31_0311
gene_biotype: protein_coding
description:
  Sulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.


ensembl_gene_id: DB31_0312
symbol: DB31_0312
gene_biotype: protein_coding
description:
  Sulfite reductase [NADPH] flavoprotein alpha-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.


ensembl_gene_id: DB31_0313
symbol: cysI
gene_biotype: protein_coding
description:
  Sulfite reductase [NADPH] hemoprotein beta-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.


ensembl_gene_id: DB31_0315
symbol: DB31_0315
gene_biotype: protein_coding
description:
  Sulfate transport system permease protein CysT; Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: DB31_0317
symbol: cysA
gene_biotype: protein_coding
description:
  Sulfate and thiosulfate import ATP-binding protein CysA; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system.


ensembl_gene_id: DB31_0402
symbol: DB31_0402
gene_biotype: protein_coding
description:
  Hypothetical protein; Hydrolyzes 6-aminopenicillinic acid and 7- aminocephalosporanic acid (ACA) derivatives.


ensembl_gene_id: DB31_0434
symbol: hmuV
gene_biotype: protein_coding
description:
  ABC-type hemin transport system, ATPase component; Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system.


ensembl_gene_id: DB31_0435
symbol: DB31_0435
gene_biotype: protein_coding
description:
  Hemin ABC transporter, permease protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: DB31_0449
symbol: gltS
gene_biotype: protein_coding
description:
  Sodium/glutamate symporter; Catalyzes the sodium-dependent transport of glutamate. Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.


ensembl_gene_id: DB31_0467
symbol: DB31_0467
gene_biotype: protein_coding
description:
  Formate dehydrogenase O alpha subunit protein; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: DB31_0508
symbol: dapF
gene_biotype: protein_coding
description:
  Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.


ensembl_gene_id: DB31_0511
symbol: DB31_0511
gene_biotype: protein_coding
description:
  Ribonucleotide reductase of class Ia (aerobic), alpha subunit protein; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.


ensembl_gene_id: DB31_0512
symbol: DB31_0512
gene_biotype: protein_coding
description:
  Ribonucleotide reductase of class Ia (aerobic), beta subunit protein; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.


ensembl_gene_id: DB31_0515
symbol: DB31_0515
gene_biotype: protein_coding
description:
  Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.


ensembl_gene_id: DB31_0520
symbol: prs
gene_biotype: protein_coding
description:
  Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.


ensembl_gene_id: DB31_0521
symbol: rplY
gene_biotype: protein_coding
description:
  LSU ribosomal protein L25p; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.


ensembl_gene_id: DB31_0522
symbol: pth
gene_biotype: protein_coding
description:
  Peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.


ensembl_gene_id: DB31_0524
symbol: rpsR
gene_biotype: protein_coding
description:
  SSU ribosomal protein S18p; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.


ensembl_gene_id: DB31_0526
symbol: DB31_0526
gene_biotype: protein_coding
description:
  Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily.


ensembl_gene_id: DB31_0532
symbol: thiE
gene_biotype: protein_coding
description:
  Thiamin-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.


ensembl_gene_id: DB31_0537
symbol: clpB
gene_biotype: protein_coding
description:
  ClpB protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.


ensembl_gene_id: DB31_0539
symbol: argR
gene_biotype: protein_coding
description:
  Arginine pathway regulatory protein ArgR, repressor of arg regulon; Regulates arginine biosynthesis genes.


ensembl_gene_id: DB31_0540
symbol: DB31_0540
gene_biotype: protein_coding
description:
  Ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily.


ensembl_gene_id: DB31_0547
symbol: argC
gene_biotype: protein_coding
description:
  N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.


ensembl_gene_id: DB31_0557
symbol: truA
gene_biotype: protein_coding
description:
  tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.


ensembl_gene_id: DB31_0561
symbol: DB31_0561
gene_biotype: protein_coding
description:
  Putative poly(beta-D-mannuronate) O-acetylase; Belongs to the membrane-bound acyltransferase family.


ensembl_gene_id: DB31_0566
symbol: DB31_0566
gene_biotype: protein_coding
description:
  Prevent host death protein, Phd antitoxin; Antitoxin component of a type II toxin-antitoxin (TA) system.


ensembl_gene_id: DB31_0568
symbol: DB31_0568
gene_biotype: protein_coding
description:
  2-keto-3-deoxy-D-arabino-heptulosonate-7- phosphate synthase I alpha; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP).


ensembl_gene_id: DB31_0571
symbol: speE
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.


ensembl_gene_id: DB31_0595
symbol: cheB
gene_biotype: protein_coding
description:
  Chemotaxis response regulator protein-glutamate methylesterase CheB; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.


ensembl_gene_id: DB31_0630
symbol: truD
gene_biotype: protein_coding
description:
  tRNA pseudouridine 13 synthase; Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family.


ensembl_gene_id: DB31_0638
symbol: dnaG
gene_biotype: protein_coding
description:
  DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.


ensembl_gene_id: DB31_0639
symbol: rpoD
gene_biotype: protein_coding
description:
  RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.


ensembl_gene_id: DB31_0650
symbol: ctaB
gene_biotype: protein_coding
description:
  Heme O synthase, protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.


ensembl_gene_id: DB31_0675
symbol: frr
gene_biotype: protein_coding
description:
  Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.


ensembl_gene_id: DB31_0677
symbol: tsf
gene_biotype: protein_coding
description:
  Translation elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.


ensembl_gene_id: DB31_0682
symbol: secA
gene_biotype: protein_coding
description:
  Protein export cytoplasm protein SecA ATPase RNA helicase; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family.


ensembl_gene_id: DB31_0690
symbol: DB31_0690
gene_biotype: protein_coding
description:
  D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: DB31_0691
symbol: apt
gene_biotype: protein_coding
description:
  Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.


ensembl_gene_id: DB31_0702
symbol: nadK
gene_biotype: protein_coding
description:
  NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.


ensembl_gene_id: DB31_0716
symbol: hemE
gene_biotype: protein_coding
description:
  Uroporphyrinogen III decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.


ensembl_gene_id: DB31_0752
symbol: DB31_0752
gene_biotype: protein_coding
description:
  4-carboxymuconolactone decarboxylase domain/alkylhydroperoxidase AhpD family core domain protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.


ensembl_gene_id: DB31_0822
symbol: tgt
gene_biotype: protein_coding
description:
  tRNA-guanine transglycosylase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the [...]


ensembl_gene_id: DB31_0827
symbol: DB31_0827
gene_biotype: protein_coding
description:
  dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.


ensembl_gene_id: DB31_0828
symbol: DB31_0828
gene_biotype: protein_coding
description:
  Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.


ensembl_gene_id: DB31_0829
symbol: DB31_0829
gene_biotype: protein_coding
description:
  dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family.


ensembl_gene_id: DB31_0830
symbol: DB31_0830
gene_biotype: protein_coding
description:
  dTDP-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.


ensembl_gene_id: DB31_0842
symbol: DB31_0842
gene_biotype: protein_coding
description:
  Putative Co/Zn/Cd efflux system membrane fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: DB31_0845
symbol: DB31_0845
gene_biotype: protein_coding
description:
  Maltose/maltodextrin ABC transporter, substrate binding periplasmic protein MalE; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Binds maltose and higher maltodextrins. Belongs to the bacterial solute-binding protein 1 family.


ensembl_gene_id: DB31_0855
symbol: DB31_0855
gene_biotype: protein_coding
description:
  CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: DB31_0864
symbol: pyrE
gene_biotype: protein_coding
description:
  Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).


ensembl_gene_id: DB31_0876
symbol: dxs
gene_biotype: protein_coding
description:
  1-deoxy-D-xylulose 5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.


ensembl_gene_id: DB31_0879
symbol: xseB
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease VII small subunit protein; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.


ensembl_gene_id: DB31_0880
symbol: xseA
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease VII large subunit protein; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family.


ensembl_gene_id: DB31_0906
symbol: DB31_0906
gene_biotype: protein_coding
description:
  Hypothetical protein; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.


ensembl_gene_id: DB31_0947
symbol: aspS
gene_biotype: protein_coding
description:
  Aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.


ensembl_gene_id: DB31_0987
symbol: DB31_0987
gene_biotype: protein_coding
description:
  Putative cytoplasmic protein; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.


ensembl_gene_id: DB31_1044
symbol: DB31_1044
gene_biotype: protein_coding
description:
  Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.


ensembl_gene_id: DB31_1060
symbol: DB31_1060
gene_biotype: protein_coding
description:
  2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: DB31_1061
symbol: DB31_1061
gene_biotype: protein_coding
description:
  Glutamate-1-semialdehyde aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: DB31_1065
symbol: secF
gene_biotype: protein_coding
description:
  Protein-export membrane protein SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.


ensembl_gene_id: DB31_1066
symbol: secD
gene_biotype: protein_coding
description:
  Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.


ensembl_gene_id: DB31_1067
symbol: yajC
gene_biotype: protein_coding
description:
  Preprotein translocase subunit YajC; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.


ensembl_gene_id: DB31_1069
symbol: queA
gene_biotype: protein_coding
description:
  S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).


ensembl_gene_id: DB31_1100
symbol: msrA
gene_biotype: protein_coding
description:
  Peptide methionine sulfoxide reductase MsrA; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.


ensembl_gene_id: DB31_1116
symbol: map
gene_biotype: protein_coding
description:
  Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.


ensembl_gene_id: DB31_1144
symbol: ackA
gene_biotype: protein_coding
description:
  Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.


ensembl_gene_id: DB31_1200
symbol: DB31_1200
gene_biotype: protein_coding
description:
  Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.


ensembl_gene_id: DB31_1222
symbol: recF
gene_biotype: protein_coding
description:
  DNA recombination and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family.


ensembl_gene_id: DB31_1225
symbol: DB31_1225
gene_biotype: protein_coding
description:
  DNA polymerase III beta subunit protein; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initia [...]


ensembl_gene_id: DB31_1233
symbol: infC
gene_biotype: protein_coding
description:
  Translation initiation factor 3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.


ensembl_gene_id: DB31_1248
symbol: DB31_1248
gene_biotype: protein_coding
description:
  Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.


ensembl_gene_id: DB31_1325
symbol: DB31_1325
gene_biotype: protein_coding
description:
  CDP-alcohol phosphatidyltransferase family protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: DB31_1334
symbol: DB31_1334
gene_biotype: protein_coding
description:
  Glycerol-3-phosphate dehydrogenase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.


ensembl_gene_id: DB31_1384
symbol: aat
gene_biotype: protein_coding
description:
  Leucyl/phenylalanyl-tRNA--protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.


ensembl_gene_id: DB31_1390
symbol: glgA
gene_biotype: protein_coding
description:
  Glycogen synthase, ADP-glucose transglucosylase; Synthesizes alpha-1,4-glucan chains using ADP-glucose.


ensembl_gene_id: DB31_1391
symbol: pdxH
gene_biotype: protein_coding
description:
  Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).


ensembl_gene_id: DB31_1394
symbol: DB31_1394
gene_biotype: protein_coding
description:
  Protoporphyrinogen IX oxidase, aerobic, HemY; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.


ensembl_gene_id: DB31_1405
symbol: rlmN
gene_biotype: protein_coding
description:
  Ribosomal RNA large subunit methyltransferase N; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family.


ensembl_gene_id: DB31_1413
symbol: gluQ
gene_biotype: protein_coding
description:
  glutamyl-Q-tRNA synthetase; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.


ensembl_gene_id: DB31_1437
symbol: pckG
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.


ensembl_gene_id: DB31_1442
symbol: bioD
gene_biotype: protein_coding
description:
  Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.


ensembl_gene_id: DB31_1443
symbol: bioF
gene_biotype: protein_coding
description:
  8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.


ensembl_gene_id: DB31_1444
symbol: bioB
gene_biotype: protein_coding
description:
  Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.


ensembl_gene_id: DB31_1449
symbol: radA
gene_biotype: protein_coding
description:
  DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.


ensembl_gene_id: DB31_1454
symbol: DB31_1454
gene_biotype: protein_coding
description:
  Putative Glutathione-regulated potassium-efflux system protein KefB; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.


ensembl_gene_id: DB31_1467
symbol: proA
gene_biotype: protein_coding
description:
  Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.


ensembl_gene_id: DB31_1468
symbol: rsfS
gene_biotype: protein_coding
description:
  Iojap protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.


ensembl_gene_id: DB31_1469
symbol: rlmH
gene_biotype: protein_coding
description:
  Methyltransferase; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family.


ensembl_gene_id: DB31_1478
symbol: gpmI
gene_biotype: protein_coding
description:
  2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.


ensembl_gene_id: DB31_1519
symbol: speE-3
gene_biotype: protein_coding
description:
  Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.


ensembl_gene_id: DB31_1523
symbol: DB31_1523
gene_biotype: protein_coding
description:
  S-adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.


ensembl_gene_id: DB31_1525
symbol: DB31_1525
gene_biotype: protein_coding
description:
  Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.


ensembl_gene_id: DB31_1531
symbol: menB
gene_biotype: protein_coding
description:
  Naphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA); Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.


ensembl_gene_id: DB31_1550
symbol: DB31_1550
gene_biotype: protein_coding
description:
  Cysteine desulfurase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.


ensembl_gene_id: DB31_1560
symbol: DB31_1560
gene_biotype: protein_coding
description:
  Coproporphyrinogen III oxidase, oxygen-independent; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.


ensembl_gene_id: DB31_1573
symbol: prmA
gene_biotype: protein_coding
description:
  Ribosomal protein L11 methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family.


ensembl_gene_id: DB31_1596
symbol: nadA
gene_biotype: protein_coding
description:
  Quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.


ensembl_gene_id: DB31_1605
symbol: uvrA
gene_biotype: protein_coding
description:
  Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.


ensembl_gene_id: DB31_1617
symbol: purA
gene_biotype: protein_coding
description:
  Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.


ensembl_gene_id: DB31_1630
symbol: uvrB
gene_biotype: protein_coding
description:
  Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate  [...]


ensembl_gene_id: DB31_1631
symbol: uvrC
gene_biotype: protein_coding
description:
  Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.


ensembl_gene_id: DB31_1642
symbol: DB31_1642
gene_biotype: protein_coding
description:
  Proline synthase; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.


ensembl_gene_id: DB31_1643
symbol: DB31_1643
gene_biotype: protein_coding
description:
  Septum formation protein Maf; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.


ensembl_gene_id: DB31_1650
symbol: mrdB
gene_biotype: protein_coding
description:
  Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.


ensembl_gene_id: DB31_1657
symbol: hemA
gene_biotype: protein_coding
description:
  Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).


ensembl_gene_id: DB31_1658
symbol: hemC
gene_biotype: protein_coding
description:
  Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.


ensembl_gene_id: DB31_1664
symbol: DB31_1664
gene_biotype: protein_coding
description:
  Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.


ensembl_gene_id: DB31_1685
symbol: pdhA
gene_biotype: protein_coding
description:
  Pyruvate dehydrogenase E1 component alpha subunit protein; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


ensembl_gene_id: DB31_1686
symbol: DB31_1686
gene_biotype: protein_coding
description:
  Pyruvate dehydrogenase E1 component beta subunit protein; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.


ensembl_gene_id: DB31_1687
symbol: DB31_1687
gene_biotype: protein_coding
description:
  Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


ensembl_gene_id: DB31_1694
symbol: gltX
gene_biotype: protein_coding
description:
  Glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).


ensembl_gene_id: DB31_1720
symbol: anmK
gene_biotype: protein_coding
description:
  Anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family.


ensembl_gene_id: DB31_1722
symbol: murQ
gene_biotype: protein_coding
description:
  N-acetylmuramic acid 6-phosphate etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.


ensembl_gene_id: DB31_1727
symbol: purN
gene_biotype: protein_coding
description:
  Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.


ensembl_gene_id: DB31_1732
symbol: accD
gene_biotype: protein_coding
description:
  Acetyl-coenzyme A carboxyl transferase beta chain; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.


ensembl_gene_id: DB31_1746
symbol: lptD
gene_biotype: protein_coding
description:
  Outer membrane protein; Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane; Belongs to the LptD family.


ensembl_gene_id: DB31_1768
symbol: nuoI
gene_biotype: protein_coding
description:
  NADH-ubiquinone oxidoreductase chain I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: DB31_1769
symbol: nuoH
gene_biotype: protein_coding
description:
  NADH-ubiquinone oxidoreductase chain H; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.


ensembl_gene_id: DB31_1771
symbol: nuoD
gene_biotype: protein_coding
description:
  NADH-ubiquinone oxidoreductase chain D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family.


ensembl_gene_id: DB31_1772
symbol: nuoC
gene_biotype: protein_coding
description:
  NADH-ubiquinone oxidoreductase chain C; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 30 kDa subunit family.


ensembl_gene_id: DB31_1776
symbol: nuoB
gene_biotype: protein_coding
description:
  NADH-ubiquinone oxidoreductase chain B; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: DB31_1777
symbol: nuoA
gene_biotype: protein_coding
description:
  NADH ubiquinone oxidoreductase chain A; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family.


ensembl_gene_id: DB31_1828
symbol: DB31_1828
gene_biotype: protein_coding
description:
  Molybdenum cofactor biosynthesis protein MoaB; May be involved in the biosynthesis of molybdopterin. Belongs to the MoaB/Mog family.


ensembl_gene_id: DB31_1850
symbol: DB31_1850
gene_biotype: protein_coding
description:
  Gamma-aminobutyrate:alpha-ketoglutarate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: DB31_1879
symbol: tmk
gene_biotype: protein_coding
description:
  Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.


ensembl_gene_id: DB31_1884
symbol: DB31_1884
gene_biotype: protein_coding
description:
  Hypothetical protein; CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin). Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.


ensembl_gene_id: DB31_1886
symbol: macB
gene_biotype: protein_coding
description:
  Macrolide export ATP-binding/permease protein MacB; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.


ensembl_gene_id: DB31_1907
symbol: metG
gene_biotype: protein_coding
description:
  Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.


ensembl_gene_id: DB31_1920
symbol: DB31_1920
gene_biotype: protein_coding
description:
  NAD-dependent glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.


ensembl_gene_id: DB31_1922
symbol: tpiA
gene_biotype: protein_coding
description:
  Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.


ensembl_gene_id: DB31_1923
symbol: DB31_1923
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.


ensembl_gene_id: DB31_1926
symbol: DB31_1926
gene_biotype: protein_coding
description:
  Type I restriction-modification system, restriction subunit R; Subunit R is required for both nuclease and ATPase activities, but not for modification.


ensembl_gene_id: DB31_1955
symbol: DB31_1955
gene_biotype: protein_coding
description:
  Hypothetical protein; Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella. In the N-terminal section; belongs to the bacterial solute- binding protein 3 family.


ensembl_gene_id: DB31_2004
symbol: ttcA
gene_biotype: protein_coding
description:
  tRNA(Cytosine32)-2-thiocytidine synthetase; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.


ensembl_gene_id: DB31_2007
symbol: DB31_2007
gene_biotype: protein_coding
description:
  Thermostable carboxypeptidase 1; Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.


ensembl_gene_id: DB31_2010
symbol: prfC
gene_biotype: protein_coding
description:
  Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.


ensembl_gene_id: DB31_2013
symbol: rsgA
gene_biotype: protein_coding
description:
  Putative GTPase; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.


ensembl_gene_id: DB31_2075
symbol: clpS
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease adaptor protein ClpS; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family.


ensembl_gene_id: DB31_2088
symbol: DB31_2088
gene_biotype: protein_coding
description:
  Dihydrolipoamide succinyltransferase component (E2) of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).


ensembl_gene_id: DB31_2113
symbol: msrQ
gene_biotype: protein_coding
description:
  Putative membrane protein; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, usin [...]


ensembl_gene_id: DB31_2114
symbol: msrP
gene_biotype: protein_coding
description:
  Putative sulfite oxidase subunit YedY; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce  [...]


ensembl_gene_id: DB31_2121
symbol: trpD
gene_biotype: protein_coding
description:
  Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).


ensembl_gene_id: DB31_2124
symbol: trpB
gene_biotype: protein_coding
description:
  Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.


ensembl_gene_id: DB31_2125
symbol: trpA
gene_biotype: protein_coding
description:
  Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.


ensembl_gene_id: DB31_2199
symbol: DB31_2199
gene_biotype: protein_coding
description:
  Oxidoreductase, 2OG-Fe(II) oxygenase family protein; Belongs to the iron/ascorbate-dependent oxidoreductase family.


ensembl_gene_id: DB31_2267
symbol: dnaX
gene_biotype: protein_coding
description:
  DNA polymerase III subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.


ensembl_gene_id: DB31_2271
symbol: tadA
gene_biotype: protein_coding
description:
  tRNA-specific adenosine-34 deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.


ensembl_gene_id: DB31_2272
symbol: serS
gene_biotype: protein_coding
description:
  Seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).


ensembl_gene_id: DB31_2291
symbol: cobB
gene_biotype: protein_coding
description:
  NAD-dependent protein deacetylase of SIR2 family protein; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class II subfamily.


ensembl_gene_id: DB31_2298
symbol: DB31_2298
gene_biotype: protein_coding
description:
  5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: DB31_2300
symbol: nbaC
gene_biotype: protein_coding
description:
  3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.


ensembl_gene_id: DB31_2302
symbol: kynU
gene_biotype: protein_coding
description:
  Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively.


ensembl_gene_id: DB31_2303
symbol: kmo
gene_biotype: protein_coding
description:
  Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily.


ensembl_gene_id: DB31_2325
symbol: DB31_2325
gene_biotype: protein_coding
description:
  RNA polymerase sigma factor RpoH; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.


ensembl_gene_id: DB31_2328
symbol: DB31_2328
gene_biotype: protein_coding
description:
  5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.


ensembl_gene_id: DB31_2357
symbol: DB31_2357
gene_biotype: protein_coding
description:
  Excinuclease ABC subunit A protein; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.


ensembl_gene_id: DB31_2378
symbol: ahcY
gene_biotype: protein_coding
description:
  Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.


ensembl_gene_id: DB31_2386
symbol: rplM
gene_biotype: protein_coding
description:
  LSU ribosomal protein L13p (L13Ae); This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.


ensembl_gene_id: DB31_2421
symbol: bamD
gene_biotype: protein_coding
description:
  Competence protein ComL precursor; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: DB31_2428
symbol: rph
gene_biotype: protein_coding
description:
  Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.


ensembl_gene_id: DB31_2429
symbol: DB31_2429
gene_biotype: protein_coding
description:
  Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific); Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.


ensembl_gene_id: DB31_2438
symbol: tig
gene_biotype: protein_coding
description:
  Cell division trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.


ensembl_gene_id: DB31_2439
symbol: clpP
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease proteolytic subunit protein; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.


ensembl_gene_id: DB31_2440
symbol: clpX
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.


ensembl_gene_id: DB31_2444
symbol: lon
gene_biotype: protein_coding
description:
  ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.


ensembl_gene_id: DB31_2466
symbol: DB31_2466
gene_biotype: protein_coding
description:
  Hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.


ensembl_gene_id: DB31_2483
symbol: DB31_2483
gene_biotype: protein_coding
description:
  Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.


ensembl_gene_id: DB31_2485
symbol: DB31_2485
gene_biotype: protein_coding
description:
  2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.


ensembl_gene_id: DB31_2532
symbol: DB31_2532
gene_biotype: protein_coding
description:
  Short-chain dehydrogenase/reductase SDR; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: DB31_2547
symbol: rho
gene_biotype: protein_coding
description:
  Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.


ensembl_gene_id: DB31_2550
symbol: ligA
gene_biotype: protein_coding
description:
  DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily.


ensembl_gene_id: DB31_2575
symbol: lolD
gene_biotype: protein_coding
description:
  Putative ABC transporter ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner. Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.


ensembl_gene_id: DB31_2595
symbol: lolD-2
gene_biotype: protein_coding
description:
  Lipoprotein releasing system ATP-binding protein LolD; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner. Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.


ensembl_gene_id: DB31_2631
symbol: DB31_2631
gene_biotype: protein_coding
description:
  Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.


ensembl_gene_id: DB31_2633
symbol: DB31_2633
gene_biotype: protein_coding
description:
  Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.


ensembl_gene_id: DB31_2638
symbol: DB31_2638
gene_biotype: protein_coding
description:
  Putative deoxyribose-specific ABC transporter, permease protein; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: DB31_2645
symbol: deoC
gene_biotype: protein_coding
description:
  Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.


ensembl_gene_id: DB31_2674
symbol: DB31_2674
gene_biotype: protein_coding
description:
  Cobalt/zinc/cadmium efflux RND transporter, membrane fusion protein, CzcB family protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: DB31_2680
symbol: ftsY
gene_biotype: protein_coding
description:
  Signal recognition particle receptor protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.


ensembl_gene_id: DB31_2698
symbol: ddl
gene_biotype: protein_coding
description:
  D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.


ensembl_gene_id: DB31_2704
symbol: DB31_2704
gene_biotype: protein_coding
description:
  Cell division protein FtsX; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.


ensembl_gene_id: DB31_2705
symbol: ftsE
gene_biotype: protein_coding
description:
  Cell division transporter, ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division.


ensembl_gene_id: DB31_2713
symbol: tolB
gene_biotype: protein_coding
description:
  tolB protein precursor protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: DB31_2717
symbol: DB31_2717
gene_biotype: protein_coding
description:
  Glucose/mannose:H+ symporter GlcP; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.


ensembl_gene_id: DB31_2725
symbol: DB31_2725
gene_biotype: protein_coding
description:
  Biotin carboxylase of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.


ensembl_gene_id: DB31_2726
symbol: DB31_2726
gene_biotype: protein_coding
description:
  Biotin carboxyl carrier protein of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.


ensembl_gene_id: DB31_2728
symbol: efp
gene_biotype: protein_coding
description:
  Translation elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.


ensembl_gene_id: DB31_2738
symbol: DB31_2738
gene_biotype: protein_coding
description:
  Leader peptidase (Prepilin peptidase); Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.


ensembl_gene_id: DB31_2739
symbol: DB31_2739
gene_biotype: protein_coding
description:
  Putative iron binding protein from the HesB_IscA_SufA family protein; Belongs to the HesB/IscA family.


ensembl_gene_id: DB31_2753
symbol: DB31_2753
gene_biotype: protein_coding
description:
  Methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.


ensembl_gene_id: DB31_2762
symbol: acsA
gene_biotype: protein_coding
description:
  Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.


ensembl_gene_id: DB31_2776
symbol: menA
gene_biotype: protein_coding
description:
  1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily.


ensembl_gene_id: DB31_2779
symbol: DB31_2779
gene_biotype: protein_coding
description:
  Chemotaxis protein methyltransferase CheR; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.


ensembl_gene_id: DB31_2799
symbol: rlpA
gene_biotype: protein_coding
description:
  Rare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.


ensembl_gene_id: DB31_2802
symbol: DB31_2802
gene_biotype: protein_coding
description:
  Undecaprenyl pyrophosphate synthetase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.


ensembl_gene_id: DB31_2809
symbol: dinB
gene_biotype: protein_coding
description:
  DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.


ensembl_gene_id: DB31_2812
symbol: mtnC
gene_biotype: protein_coding
description:
  2,3-diketo-5-methylthiopentyl-1-phosphate enolase-phosphatase; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.


ensembl_gene_id: DB31_2813
symbol: mtnD
gene_biotype: protein_coding
description:
  1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.


ensembl_gene_id: DB31_2814
symbol: mtnB
gene_biotype: protein_coding
description:
  Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Belongs to the aldolase class II family. MtnB subfamily.


ensembl_gene_id: DB31_2816
symbol: pcnB
gene_biotype: protein_coding
description:
  Poly(A) polymerase; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control. Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.


ensembl_gene_id: DB31_2820
symbol: plsX
gene_biotype: protein_coding
description:
  Phosphate:acyl-ACP acyltransferase PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.


ensembl_gene_id: DB31_2827
symbol: purE
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazole carboxylase catalytic subunit protein; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).


ensembl_gene_id: DB31_2828
symbol: purK
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazole carboxylase ATPase subunit protein; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).


ensembl_gene_id: DB31_2873
symbol: DB31_2873
gene_biotype: protein_coding
description:
  Type IV fimbrial assembly, ATPase PilB; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.


ensembl_gene_id: DB31_2953
symbol: DB31_2953
gene_biotype: protein_coding
description:
  Putative Holliday junction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family.


ensembl_gene_id: DB31_2963
symbol: DB31_2963
gene_biotype: protein_coding
description:
  Glycogen phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.


ensembl_gene_id: DB31_3002
symbol: DB31_3002
gene_biotype: protein_coding
description:
  3-oxoacyl-[acyl-carrier-protein] synthase, KASII; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: DB31_3044
symbol: tatC
gene_biotype: protein_coding
description:
  Twin-arginine translocation protein TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.


ensembl_gene_id: DB31_3054
symbol: DB31_3054
gene_biotype: protein_coding
description:
  Ribosomal large subunit pseudouridine synthase C; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.


ensembl_gene_id: DB31_3073
symbol: tal
gene_biotype: protein_coding
description:
  Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.


ensembl_gene_id: DB31_3111
symbol: dapB
gene_biotype: protein_coding
description:
  Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.


ensembl_gene_id: DB31_3112
symbol: dapA
gene_biotype: protein_coding
description:
  Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).


ensembl_gene_id: DB31_3113
symbol: lysA
gene_biotype: protein_coding
description:
  Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.


ensembl_gene_id: DB31_3117
symbol: DB31_3117
gene_biotype: protein_coding
description:
  Formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.


ensembl_gene_id: DB31_3118
symbol: DB31_3118
gene_biotype: protein_coding
description:
  Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.


ensembl_gene_id: DB31_3121
symbol: ku
gene_biotype: protein_coding
description:
  Ku domain protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.


ensembl_gene_id: DB31_3130
symbol: thyA
gene_biotype: protein_coding
description:
  Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.


ensembl_gene_id: DB31_3131
symbol: DB31_3131
gene_biotype: protein_coding
description:
  Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.


ensembl_gene_id: DB31_3161
symbol: DB31_3161
gene_biotype: protein_coding
description:
  RNA polymerase, sigma-24 subunit, ECF subfamily protein; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: DB31_3192
symbol: rnz
gene_biotype: protein_coding
description:
  Ribonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family.


ensembl_gene_id: DB31_3198
symbol: purL
gene_biotype: protein_coding
description:
  Phosphoribosylformylglycinamidine synthase, synthetase subunit protein; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.


ensembl_gene_id: DB31_3202
symbol: hppA
gene_biotype: protein_coding
description:
  Pyrophosphate-energized proton pump; Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.


ensembl_gene_id: DB31_3240
symbol: dnaJ
gene_biotype: protein_coding
description:
  Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]


ensembl_gene_id: DB31_3254
symbol: ung
gene_biotype: protein_coding
description:
  Uracil-DNA glycosylase, family 1; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.


ensembl_gene_id: DB31_3272
symbol: gyrA
gene_biotype: protein_coding
description:
  DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.


ensembl_gene_id: DB31_3276
symbol: ureG
gene_biotype: protein_coding
description:
  Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.


ensembl_gene_id: DB31_3277
symbol: ureF
gene_biotype: protein_coding
description:
  Urease accessory protein UreF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.


ensembl_gene_id: DB31_3280
symbol: ureD
gene_biotype: protein_coding
description:
  Urease accessory protein UreD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.


ensembl_gene_id: DB31_3437
symbol: DB31_3437
gene_biotype: protein_coding
description:
  6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.


ensembl_gene_id: DB31_3439
symbol: zwf
gene_biotype: protein_coding
description:
  Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.


ensembl_gene_id: DB31_3465
symbol: sbcD
gene_biotype: protein_coding
description:
  Exonuclease SbcD; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.


ensembl_gene_id: DB31_3562
symbol: mfd
gene_biotype: protein_coding
description:
  Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.


ensembl_gene_id: DB31_3570
symbol: DB31_3570
gene_biotype: protein_coding
description:
  Menaquinone-cytochrome c reductase, cytochrome B subunit protein; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.


ensembl_gene_id: DB31_3608
symbol: DB31_3608
gene_biotype: protein_coding
description:
  Omega-amino acid--pyruvate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: DB31_3610
symbol: DB31_3610
gene_biotype: protein_coding
description:
  Short-chain dehydrogenase/reductase (SDR) protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: DB31_3652
symbol: astB
gene_biotype: protein_coding
description:
  Succinylarginine dihydrolase; Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)- succinylornithine, ammonia and CO(2).


ensembl_gene_id: DB31_3657
symbol: DB31_3657
gene_biotype: protein_coding
description:
  RNA polymerase sigma-54 factor RpoN; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.


ensembl_gene_id: DB31_3661
symbol: hpf
gene_biotype: protein_coding
description:
  Ribosomal subunit interface protein; Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.


ensembl_gene_id: DB31_3667
symbol: dtd
gene_biotype: protein_coding
description:
  D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family.


ensembl_gene_id: DB31_3677
symbol: DB31_3677
gene_biotype: protein_coding
description:
  Single-stranded DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.


ensembl_gene_id: DB31_3686
symbol: nuoN
gene_biotype: protein_coding
description:
  NADH-ubiquinone oxidoreductase chain N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family.


ensembl_gene_id: DB31_3689
symbol: nuoK
gene_biotype: protein_coding
description:
  NADH-ubiquinone oxidoreductase chain K; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family.


ensembl_gene_id: DB31_3690
symbol: DB31_3690
gene_biotype: protein_coding
description:
  NADH-ubiquinone oxidoreductase chain J; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: DB31_3691
symbol: DB31_3691
gene_biotype: protein_coding
description:
  NADH-ubiquinone oxidoreductase chain F; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family.


ensembl_gene_id: DB31_3702
symbol: pyrG
gene_biotype: protein_coding
description:
  CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.


ensembl_gene_id: DB31_3715
symbol: kdsB
gene_biotype: protein_coding
description:
  3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.


ensembl_gene_id: DB31_3721
symbol: purF
gene_biotype: protein_coding
description:
  Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.


ensembl_gene_id: DB31_3728
symbol: DB31_3728
gene_biotype: protein_coding
description:
  Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.


ensembl_gene_id: DB31_3770
symbol: DB31_3770
gene_biotype: protein_coding
description:
  6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family.


ensembl_gene_id: DB31_3791
symbol: DB31_3791
gene_biotype: protein_coding
description:
  D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: DB31_3816
symbol: DB31_3816
gene_biotype: protein_coding
description:
  Folate-dependent protein for Fe/S cluster synthesis/repair in oxidative stress; Belongs to the GcvT family.


ensembl_gene_id: DB31_3830
symbol: DB31_3830
gene_biotype: protein_coding
description:
  Putative sodium:dicarboxylate symporter; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: DB31_3832
symbol: dusA
gene_biotype: protein_coding
description:
  tRNA dihydrouridine synthase A; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily.


ensembl_gene_id: DB31_3880
symbol: ppk
gene_biotype: protein_coding
description:
  Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family.


ensembl_gene_id: DB31_3885
symbol: mltG
gene_biotype: protein_coding
description:
  Hypothetical protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.


ensembl_gene_id: DB31_3886
symbol: truB
gene_biotype: protein_coding
description:
  tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.


ensembl_gene_id: DB31_3887
symbol: queF
gene_biotype: protein_coding
description:
  NADPH dependent preQ0 reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.


ensembl_gene_id: DB31_3936
symbol: DB31_3936
gene_biotype: protein_coding
description:
  5-Hydroxyisourate Hydrolase (HIUase); Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.


ensembl_gene_id: DB31_3956
symbol: nadE
gene_biotype: protein_coding
description:
  NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.


ensembl_gene_id: DB31_4038
symbol: atpC
gene_biotype: protein_coding
description:
  ATP synthase epsilon chain; Produces ATP from ADP in the presence of a proton gradient across the membrane.


ensembl_gene_id: DB31_4040
symbol: atpD
gene_biotype: protein_coding
description:
  ATP synthase beta chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.


ensembl_gene_id: DB31_4041
symbol: atpG
gene_biotype: protein_coding
description:
  ATP synthase gamma chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.


ensembl_gene_id: DB31_4130
symbol: atpH
gene_biotype: protein_coding
description:
  ATP synthase delta chain; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.


ensembl_gene_id: DB31_4132
symbol: atpA
gene_biotype: protein_coding
description:
  ATP synthase alpha chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.


ensembl_gene_id: DB31_4154
symbol: DB31_4154
gene_biotype: protein_coding
description:
  23S rRNA (guanosine-2'-O-) -methyltransferase rlmB; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.


ensembl_gene_id: DB31_4167
symbol: DB31_4167
gene_biotype: protein_coding
description:
  Ferredoxin; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.


ensembl_gene_id: DB31_4173
symbol: DB31_4173
gene_biotype: protein_coding
description:
  Cobalt-zinc-cadmium resistance protein; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.


ensembl_gene_id: DB31_4176
symbol: gcvP
gene_biotype: protein_coding
description:
  Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.


ensembl_gene_id: DB31_4177
symbol: gcvH
gene_biotype: protein_coding
description:
  Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.


ensembl_gene_id: DB31_4178
symbol: gcvT
gene_biotype: protein_coding
description:
  Aminomethyltransferase (glycine cleavage system T protein); The glycine cleavage system catalyzes the degradation of glycine.


ensembl_gene_id: DB31_4179
symbol: DB31_4179
gene_biotype: protein_coding
description:
  5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.


ensembl_gene_id: DB31_4183
symbol: folD
gene_biotype: protein_coding
description:
  Methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.


ensembl_gene_id: DB31_4187
symbol: pyrD
gene_biotype: protein_coding
description:
  Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.


ensembl_gene_id: DB31_4195
symbol: engB
gene_biotype: protein_coding
description:
  GTP-binding protein EngB; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.


ensembl_gene_id: DB31_4198
symbol: coaE
gene_biotype: protein_coding
description:
  Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.


ensembl_gene_id: DB31_4204
symbol: argD
gene_biotype: protein_coding
description:
  Acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.


ensembl_gene_id: DB31_4205
symbol: hslU
gene_biotype: protein_coding
description:
  ATP-dependent hsl protease ATP-binding subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.


ensembl_gene_id: DB31_4206
symbol: hslV
gene_biotype: protein_coding
description:
  ATP-dependent protease HslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.


ensembl_gene_id: DB31_4222
symbol: xerC
gene_biotype: protein_coding
description:
  Tyrosine recombinase XerC; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.


ensembl_gene_id: DB31_4225
symbol: trmFO
gene_biotype: protein_coding
description:
  tRNA:m(5)U-54 MTase gid; Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs; Belongs to the MnmG family. TrmFO subfamily.


ensembl_gene_id: DB31_4230
symbol: topA
gene_biotype: protein_coding
description:
  DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]


ensembl_gene_id: DB31_4244
symbol: ilvE
gene_biotype: protein_coding
description:
  Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: DB31_4252
symbol: tyrS
gene_biotype: protein_coding
description:
  Tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.


ensembl_gene_id: DB31_4256
symbol: rlmE
gene_biotype: protein_coding
description:
  Cell division protein FtsJ; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.


ensembl_gene_id: DB31_4274
symbol: tatA
gene_biotype: protein_coding
description:
  Twin-arginine translocation protein TatA; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.


ensembl_gene_id: DB31_4282
symbol: DB31_4282
gene_biotype: protein_coding
description:
  Zinc ABC transporter, periplasmic-binding protein ZnuA; Belongs to the bacterial solute-binding protein 9 family.


ensembl_gene_id: DB31_4300
symbol: pstB
gene_biotype: protein_coding
description:
  Phosphate transport ATP-binding protein PstB; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.


ensembl_gene_id: DB31_4302
symbol: DB31_4302
gene_biotype: protein_coding
description:
  Phosphate transport system permease protein PstC; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: DB31_4304
symbol: DB31_4304
gene_biotype: protein_coding
description:
  Na+/H+ antiporter; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.


ensembl_gene_id: DB31_4307
symbol: DB31_4307
gene_biotype: protein_coding
description:
  Ribonucleotide reductase of class II (coenzyme B12-dependent); Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.


ensembl_gene_id: DB31_4333
symbol: DB31_4333
gene_biotype: protein_coding
description:
  CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: DB31_4345
symbol: DB31_4345
gene_biotype: protein_coding
description:
  Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.


ensembl_gene_id: DB31_4346
symbol: recR
gene_biotype: protein_coding
description:
  Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.


ensembl_gene_id: DB31_4368
symbol: DB31_4368
gene_biotype: protein_coding
description:
  Hypothetical protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.


ensembl_gene_id: DB31_4482
symbol: gpsA
gene_biotype: protein_coding
description:
  Glycerol-3-phosphate dehydrogenase; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.


ensembl_gene_id: DB31_4486
symbol: hflX-2
gene_biotype: protein_coding
description:
  GTP-binding protein HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.


ensembl_gene_id: DB31_4487
symbol: proB
gene_biotype: protein_coding
description:
  Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.


ensembl_gene_id: DB31_4510
symbol: def
gene_biotype: protein_coding
description:
  Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.


ensembl_gene_id: DB31_4563
symbol: mtgA
gene_biotype: protein_coding
description:
  Monofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family.


ensembl_gene_id: DB31_4583
symbol: ftsZ
gene_biotype: protein_coding
description:
  Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.


ensembl_gene_id: DB31_4585
symbol: ftsA
gene_biotype: protein_coding
description:
  Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.


ensembl_gene_id: DB31_4586
symbol: ftsQ
gene_biotype: protein_coding
description:
  Cell division protein FtsQ; Essential cell division protein; Belongs to the FtsQ/DivIB family. FtsQ subfamily.


ensembl_gene_id: DB31_4590
symbol: murG
gene_biotype: protein_coding
description:
  UDP-N-acetylglucosamine N-acetylglucosamine transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.


ensembl_gene_id: DB31_4592
symbol: murD
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.


ensembl_gene_id: DB31_4593
symbol: mraY
gene_biotype: protein_coding
description:
  Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.


ensembl_gene_id: DB31_4594
symbol: murF
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.


ensembl_gene_id: DB31_4595
symbol: murE
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.


ensembl_gene_id: DB31_4598
symbol: rsmH
gene_biotype: protein_coding
description:
  rRNA small subunit methyltransferase H; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.


ensembl_gene_id: DB31_4629
symbol: proS
gene_biotype: protein_coding
description:
  Prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).


ensembl_gene_id: DB31_4633
symbol: DB31_4633
gene_biotype: protein_coding
description:
  2'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family.


ensembl_gene_id: DB31_4643
symbol: DB31_4643
gene_biotype: protein_coding
description:
  Branched-chain amino acid transport system permease protein LivM; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: DB31_4644
symbol: DB31_4644
gene_biotype: protein_coding
description:
  High-affinity branched-chain amino acid transport system permease protein LivH; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: DB31_4651
symbol: grpE
gene_biotype: protein_coding
description:
  Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...]


ensembl_gene_id: DB31_4670
symbol: thiL
gene_biotype: protein_coding
description:
  Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.


ensembl_gene_id: DB31_4692
symbol: kup
gene_biotype: protein_coding
description:
  Kup system potassium uptake protein; Transport of potassium into the cell; Belongs to the HAK/KUP transporter (TC 2.A.72) family.


ensembl_gene_id: DB31_4695
symbol: hrcA
gene_biotype: protein_coding
description:
  Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons.


ensembl_gene_id: DB31_4740
symbol: hemF
gene_biotype: protein_coding
description:
  Coproporphyrinogen III oxidase, aerobic; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX.


ensembl_gene_id: DB31_4751
symbol: glpK
gene_biotype: protein_coding
description:
  Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.


ensembl_gene_id: DB31_4762
symbol: DB31_4762
gene_biotype: protein_coding
description:
  2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family.


ensembl_gene_id: DB31_4818
symbol: trmL
gene_biotype: protein_coding
description:
  tRNA (cytosine34-2'-O-)-methyltransferase; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.


ensembl_gene_id: DB31_4826
symbol: DB31_4826
gene_biotype: protein_coding
description:
  Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.


ensembl_gene_id: DB31_4891
symbol: rpsJ
gene_biotype: protein_coding
description:
  SSU ribosomal protein S10p (S20e); Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.


ensembl_gene_id: DB31_4893
symbol: rplW
gene_biotype: protein_coding
description:
  LSU ribosomal protein L23p (L23Ae); One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.


ensembl_gene_id: DB31_4894
symbol: rplB
gene_biotype: protein_coding
description:
  LSU ribosomal protein L2p (L8e); One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.


ensembl_gene_id: DB31_4895
symbol: rpsS
gene_biotype: protein_coding
description:
  SSU ribosomal protein S19p (S15e); Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.


ensembl_gene_id: DB31_4896
symbol: rplV
gene_biotype: protein_coding
description:
  LSU ribosomal protein L22p (L17e); The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.


ensembl_gene_id: DB31_4897
symbol: rpsC
gene_biotype: protein_coding
description:
  SSU ribosomal protein S3p (S3e); Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.


ensembl_gene_id: DB31_4898
symbol: rplP
gene_biotype: protein_coding
description:
  LSU ribosomal protein L16p (L10e); Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.


ensembl_gene_id: DB31_4900
symbol: rpsQ
gene_biotype: protein_coding
description:
  SSU ribosomal protein S17p (S11e); One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.


ensembl_gene_id: DB31_4901
symbol: rplN
gene_biotype: protein_coding
description:
  LSU ribosomal protein L14p (L23e); Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.


ensembl_gene_id: DB31_4902
symbol: rplX
gene_biotype: protein_coding
description:
  LSU ribosomal protein L24p (L26e); One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.


ensembl_gene_id: DB31_4903
symbol: rplE
gene_biotype: protein_coding
description:
  LSU ribosomal protein L5p (L11e); This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.


ensembl_gene_id: DB31_4904
symbol: rpsZ
gene_biotype: protein_coding
description:
  SSU ribosomal protein S14p (S29e); Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.


ensembl_gene_id: DB31_4905
symbol: rpsH
gene_biotype: protein_coding
description:
  SSU ribosomal protein S8p (S15Ae); One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.


ensembl_gene_id: DB31_4906
symbol: rplF
gene_biotype: protein_coding
description:
  LSU ribosomal protein L6p (L9e); This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.


ensembl_gene_id: DB31_4907
symbol: rplR
gene_biotype: protein_coding
description:
  LSU ribosomal protein L18p (L5e); This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.


ensembl_gene_id: DB31_4908
symbol: rpsE
gene_biotype: protein_coding
description:
  SSU ribosomal protein S5p (S2e); Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.


ensembl_gene_id: DB31_4910
symbol: rplO
gene_biotype: protein_coding
description:
  LSU ribosomal protein L15p (L27Ae); Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.


ensembl_gene_id: DB31_4911
symbol: secY
gene_biotype: protein_coding
description:
  Preprotein translocase secY subunit protein; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.


ensembl_gene_id: DB31_4912
symbol: adk
gene_biotype: protein_coding
description:
  Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.


ensembl_gene_id: DB31_4914
symbol: infA
gene_biotype: protein_coding
description:
  Translation initiation factor 1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.


ensembl_gene_id: DB31_4916
symbol: rpsM
gene_biotype: protein_coding
description:
  SSU ribosomal protein S13p (S18e); Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family.


ensembl_gene_id: DB31_4917
symbol: rpsK
gene_biotype: protein_coding
description:
  SSU ribosomal protein S11p (S14e); Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.


ensembl_gene_id: DB31_4918
symbol: rpsD
gene_biotype: protein_coding
description:
  SSU ribosomal protein S4p (S9e); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.


ensembl_gene_id: DB31_4919
symbol: rpoA
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase alpha subunit protein; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: DB31_4923
symbol: DB31_4923
gene_biotype: protein_coding
description:
  1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.


ensembl_gene_id: DB31_4927
symbol: psuG
gene_biotype: protein_coding
description:
  Indigoidine synthase A-like protein; Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway; Belongs to the pseudouridine-5'-phosphate glycosidase family.


ensembl_gene_id: DB31_4948
symbol: selA
gene_biotype: protein_coding
description:
  L-seryl-tRNA(Sec) selenium transferase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.


ensembl_gene_id: DB31_4973
symbol: rplC
gene_biotype: protein_coding
description:
  LSU ribosomal protein L3p (L3e); One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.


ensembl_gene_id: DB31_4998
symbol: coaD
gene_biotype: protein_coding
description:
  Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.


ensembl_gene_id: DB31_5049
symbol: greA
gene_biotype: protein_coding
description:
  Transcription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.


ensembl_gene_id: DB31_5050
symbol: recG
gene_biotype: protein_coding
description:
  ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily.


ensembl_gene_id: DB31_5051
symbol: pcm
gene_biotype: protein_coding
description:
  Protein-L-isoaspartate O-methyltransferase; Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.


ensembl_gene_id: DB31_5053
symbol: DB31_5053
gene_biotype: protein_coding
description:
  Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.


ensembl_gene_id: DB31_5061
symbol: nhaA
gene_biotype: protein_coding
description:
  Na+/H+ antiporter NhaA type; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.


ensembl_gene_id: DB31_5062
symbol: mutS
gene_biotype: protein_coding
description:
  DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.


ensembl_gene_id: DB31_5070
symbol: DB31_5070
gene_biotype: protein_coding
description:
  YrdC/Sua5 family protein, required for threonylcarbamoyladenosine (t(6)A) formation in tRNA; Belongs to the SUA5 family.


ensembl_gene_id: DB31_5072
symbol: xerD
gene_biotype: protein_coding
description:
  Site-specific recombinase XerD; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.


ensembl_gene_id: DB31_5078
symbol: DB31_5078
gene_biotype: protein_coding
description:
  Segregation and condensation protein A; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.


ensembl_gene_id: DB31_5079
symbol: DB31_5079
gene_biotype: protein_coding
description:
  Segregation and condensation protein B; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.


ensembl_gene_id: DB31_5096
symbol: rtcA
gene_biotype: protein_coding
description:
  RNA 3'-terminal phosphate cyclase; Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.


ensembl_gene_id: DB31_5104
symbol: DB31_5104
gene_biotype: protein_coding
description:
  Hypothetical protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.


ensembl_gene_id: DB31_5117
symbol: DB31_5117
gene_biotype: protein_coding
description:
  SSU ribosomal protein S1p; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.


ensembl_gene_id: DB31_5124
symbol: DB31_5124
gene_biotype: protein_coding
description:
  RNA methyltransferase, TrmA family protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.


ensembl_gene_id: DB31_5129
symbol: miaB
gene_biotype: protein_coding
description:
  tRNA-i(6)A37 methylthiotransferase; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.


ensembl_gene_id: DB31_5134
symbol: guaB
gene_biotype: protein_coding
description:
  Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.


ensembl_gene_id: DB31_5159
symbol: der
gene_biotype: protein_coding
description:
  GTP-binding protein EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.


ensembl_gene_id: DB31_5160
symbol: era
gene_biotype: protein_coding
description:
  GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.


ensembl_gene_id: DB31_5163
symbol: rnc
gene_biotype: protein_coding
description:
  Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.


ensembl_gene_id: DB31_5192
symbol: DB31_5192
gene_biotype: protein_coding
description:
  Ribosomal RNA small subunit methyltransferase B; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.


ensembl_gene_id: DB31_5197
symbol: miaA
gene_biotype: protein_coding
description:
  tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.


ensembl_gene_id: DB31_5207
symbol: psd
gene_biotype: protein_coding
description:
  Phosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).


ensembl_gene_id: DB31_5245
symbol: DB31_5245
gene_biotype: protein_coding
description:
  Protein-L-isoD(D-D) O-methyltransferase; Specifically methylates the guanosine in position 1516 of 16S rRNA.


ensembl_gene_id: DB31_5249
symbol: DB31_5249
gene_biotype: protein_coding
description:
  Cell division protein DivIC (FtsB), stabilizes FtsL against RasP cleavage; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.


ensembl_gene_id: DB31_5273
symbol: glgE
gene_biotype: protein_coding
description:
  Alpha-amylase; Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.


ensembl_gene_id: DB31_5276
symbol: glgB
gene_biotype: protein_coding
description:
  1,4-alpha-glucan (glycogen) branching enzyme, GH-13-type; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.


ensembl_gene_id: DB31_5290
symbol: queE
gene_biotype: protein_coding
description:
  Queuosine Biosynthesis QueE Radical SAM; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.


ensembl_gene_id: DB31_5291
symbol: queC
gene_biotype: protein_coding
description:
  Queuosine Biosynthesis QueC ATPase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.


ensembl_gene_id: DB31_5302
symbol: ihfA
gene_biotype: protein_coding
description:
  Integration host factor alpha subunit protein; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.


ensembl_gene_id: DB31_5303
symbol: pheT
gene_biotype: protein_coding
description:
  Phenylalanyl-tRNA synthetase beta chain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.


ensembl_gene_id: DB31_5304
symbol: pheS
gene_biotype: protein_coding
description:
  Phenylalanyl-tRNA synthetase alpha chain; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.


ensembl_gene_id: DB31_5305
symbol: rplT
gene_biotype: protein_coding
description:
  LSU ribosomal protein L20p; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.


ensembl_gene_id: DB31_5308
symbol: thrS
gene_biotype: protein_coding
description:
  Threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).


ensembl_gene_id: DB31_5353
symbol: murJ
gene_biotype: protein_coding
description:
  Putative peptidoglycan lipid II flippase MurJ; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.


ensembl_gene_id: DB31_5359
symbol: rsmI
gene_biotype: protein_coding
description:
  rRNA small subunit methyltransferase I; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.


ensembl_gene_id: DB31_5372
symbol: DB31_5372
gene_biotype: protein_coding
description:
  Oxidoreductase, short-chain dehydrogenase/reductase family protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: DB31_5378
symbol: rplS
gene_biotype: protein_coding
description:
  LSU ribosomal protein L19p; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.


ensembl_gene_id: DB31_5379
symbol: trmD
gene_biotype: protein_coding
description:
  tRNA (Guanine37-N1) -methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.


ensembl_gene_id: DB31_5380
symbol: rimM
gene_biotype: protein_coding
description:
  16S rRNA processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family.


ensembl_gene_id: DB31_5385
symbol: ndk
gene_biotype: protein_coding
description:
  Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.


ensembl_gene_id: DB31_5386
symbol: sucD
gene_biotype: protein_coding
description:
  Succinyl-CoA ligase [ADP-forming] alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.


ensembl_gene_id: DB31_5387
symbol: sucC
gene_biotype: protein_coding
description:
  Succinyl-CoA ligase [ADP-forming] beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.


ensembl_gene_id: DB31_5390
symbol: mdh
gene_biotype: protein_coding
description:
  Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.


ensembl_gene_id: DB31_5395
symbol: menC
gene_biotype: protein_coding
description:
  O-succinylbenzoate synthase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB).


ensembl_gene_id: DB31_5397
symbol: menH
gene_biotype: protein_coding
description:
  2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Catalyzes a proton abstraction reaction that results in 2,5- elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6- hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).


ensembl_gene_id: DB31_5398
symbol: menD
gene_biotype: protein_coding
description:
  2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily.


ensembl_gene_id: DB31_5400
symbol: ubiE
gene_biotype: protein_coding
description:
  2-heptaprenyl-1,4-naphthoquinone methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2).


ensembl_gene_id: DB31_5403
symbol: aroC
gene_biotype: protein_coding
description:
  Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.


ensembl_gene_id: DB31_5405
symbol: DB31_5405
gene_biotype: protein_coding
description:
  5-Enolpyruvylshikimate-3-phosphate synthase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.


ensembl_gene_id: DB31_5413
symbol: DB31_5413
gene_biotype: protein_coding
description:
  Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.


ensembl_gene_id: DB31_5417
symbol: pyrC
gene_biotype: protein_coding
description:
  Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.


ensembl_gene_id: DB31_5418
symbol: pyrB
gene_biotype: protein_coding
description:
  Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.


ensembl_gene_id: DB31_5420
symbol: lepA
gene_biotype: protein_coding
description:
  Translation elongation factor LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.


ensembl_gene_id: DB31_5429
symbol: mnmA
gene_biotype: protein_coding
description:
  tRNA-specific 2-thiouridylase MnmA; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.


ensembl_gene_id: DB31_5491
symbol: DB31_5491
gene_biotype: protein_coding
description:
  Hypothetical protein; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.


ensembl_gene_id: DB31_5494
symbol: DB31_5494
gene_biotype: protein_coding
description:
  Inner membrane component of tripartite multidrug resistance system; Belongs to the major facilitator superfamily.


ensembl_gene_id: DB31_5501
symbol: trpB-2
gene_biotype: protein_coding
description:
  Tryptophan synthase beta chain protein; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.


ensembl_gene_id: DB31_5511
symbol: DB31_5511
gene_biotype: protein_coding
description:
  NAD(P) transhydrogenase alpha subunit protein; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the AlaDH/PNT family.


ensembl_gene_id: DB31_5512
symbol: DB31_5512
gene_biotype: protein_coding
description:
  NAD(P) transhydrogenase subunit beta; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.


ensembl_gene_id: DB31_5524
symbol: DB31_5524
gene_biotype: protein_coding
description:
  RND multidrug efflux transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: DB31_5534
symbol: DB31_5534
gene_biotype: protein_coding
description:
  Putative sugar ABC transport system, permease protein YjfF; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: DB31_5535
symbol: DB31_5535
gene_biotype: protein_coding
description:
  Ribose ABC transport system, permease protein RbsC; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: DB31_5573
symbol: lnt
gene_biotype: protein_coding
description:
  Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily.


ensembl_gene_id: DB31_5577
symbol: dnaE2
gene_biotype: protein_coding
description:
  DNA polymerase III alpha subunit protein; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.


ensembl_gene_id: DB31_5669
symbol: mutL
gene_biotype: protein_coding
description:
  DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.


ensembl_gene_id: DB31_5680
symbol: accA
gene_biotype: protein_coding
description:
  Acetyl-coenzyme A carboxyl transferase alpha chain; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.


ensembl_gene_id: DB31_5711
symbol: DB31_5711
gene_biotype: protein_coding
description:
  Acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: DB31_5758
symbol: lspA
gene_biotype: protein_coding
description:
  Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.


ensembl_gene_id: DB31_5778
symbol: recD2
gene_biotype: protein_coding
description:
  RecD-like DNA helicase YrrC; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily.


ensembl_gene_id: DB31_5784
symbol: selO
gene_biotype: protein_coding
description:
  Selenoprotein O and cysteine-containing protein; Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation). Belongs to the SELO family.


ensembl_gene_id: DB31_5846
symbol: proC
gene_biotype: protein_coding
description:
  Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.


ensembl_gene_id: DB31_5862
symbol: polA
gene_biotype: protein_coding
description:
  DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.


ensembl_gene_id: DB31_5889
symbol: rpoC
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase beta' subunit protein; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: DB31_5890
symbol: rpoB
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase beta subunit protein; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: DB31_5891
symbol: rplL
gene_biotype: protein_coding
description:
  LSU ribosomal protein L7/L12 (P1/P2); Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family.


ensembl_gene_id: DB31_5892
symbol: rplJ
gene_biotype: protein_coding
description:
  LSU ribosomal protein L10p (P0); Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.


ensembl_gene_id: DB31_5893
symbol: rplA
gene_biotype: protein_coding
description:
  LSU ribosomal protein L1p (L10Ae); Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.


ensembl_gene_id: DB31_5894
symbol: rplK
gene_biotype: protein_coding
description:
  LSU ribosomal protein L11p (L12e); Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.


ensembl_gene_id: DB31_5895
symbol: nusG
gene_biotype: protein_coding
description:
  Transcription antitermination protein NusG; Participates in transcription elongation, termination and antitermination.


ensembl_gene_id: DB31_5896
symbol: secE
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61-gamma family.


ensembl_gene_id: DB31_5943
symbol: DB31_5943
gene_biotype: protein_coding
description:
  tRNA dihydrouridine synthase B; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.


ensembl_gene_id: DB31_5962
symbol: ftsH
gene_biotype: protein_coding
description:
  Cell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family.  In the central section; belongs to the AAA ATPase family.


ensembl_gene_id: DB31_5995
symbol: DB31_5995
gene_biotype: protein_coding
description:
  Ribosomal RNA small subunit methyltransferase E; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.


ensembl_gene_id: DB31_6044
symbol: tsaD
gene_biotype: protein_coding
description:
  YgjD/Kae1/Qri7 family, required for threonylcarbamoyladenosine (t(6)A) formation in tRNA; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.


ensembl_gene_id: DB31_6045
symbol: rsmA
gene_biotype: protein_coding
description:
  Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.


ensembl_gene_id: DB31_6053
symbol: DB31_6053
gene_biotype: protein_coding
description:
  3-oxoacyl-[acyl-carrier-protein] synthase, KASII; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.


ensembl_gene_id: DB31_6056
symbol: panB
gene_biotype: protein_coding
description:
  3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.


ensembl_gene_id: DB31_6057
symbol: panC
gene_biotype: protein_coding
description:
  Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.


ensembl_gene_id: DB31_6058
symbol: smpB
gene_biotype: protein_coding
description:
  tmRNA-binding protein SmpB; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switc [...]


ensembl_gene_id: DB31_6067
symbol: rimP
gene_biotype: protein_coding
description:
  Hypothetical protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.


ensembl_gene_id: DB31_6068
symbol: nusA
gene_biotype: protein_coding
description:
  Transcription termination protein NusA; Participates in both transcription termination and antitermination.


ensembl_gene_id: DB31_6070
symbol: infB
gene_biotype: protein_coding
description:
  Translation initiation factor 2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.


ensembl_gene_id: DB31_6072
symbol: rbfA
gene_biotype: protein_coding
description:
  Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.


ensembl_gene_id: DB31_6075
symbol: rpsO
gene_biotype: protein_coding
description:
  SSU ribosomal protein S15p (S13e); Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.


ensembl_gene_id: DB31_6076
symbol: pnp
gene_biotype: protein_coding
description:
  Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.


ensembl_gene_id: DB31_6084
symbol: dut
gene_biotype: protein_coding
description:
  Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.


ensembl_gene_id: DB31_6106
symbol: purU
gene_biotype: protein_coding
description:
  Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).


ensembl_gene_id: DB31_6118
symbol: DB31_6118
gene_biotype: protein_coding
description:
  Glutamate--cysteine ligase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.


ensembl_gene_id: DB31_6129
symbol: alaS
gene_biotype: protein_coding
description:
  Alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.


ensembl_gene_id: DB31_6141
symbol: trmB
gene_biotype: protein_coding
description:
  tRNA (guanine46-N7-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.


ensembl_gene_id: DB31_6190
symbol: ppc
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family.


ensembl_gene_id: DB31_6205
symbol: DB31_6205
gene_biotype: protein_coding
description:
  Fumarate hydratase class I protein; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.


ensembl_gene_id: DB31_6220
symbol: DB31_6220
gene_biotype: protein_coding
description:
  Ornithine cyclodeaminase; Catalyzes the NAD(+)-dependent oxidative deamination of L- alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate; Belongs to the ornithine cyclodeaminase/mu-crystallin family. Archaeal alanine dehydrogenase subfamily.


ensembl_gene_id: DB31_6291
symbol: groL
gene_biotype: protein_coding
description:
  Heat shock protein 60 family chaperone GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.


ensembl_gene_id: DB31_6297
symbol: valS
gene_biotype: protein_coding
description:
  Valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.


ensembl_gene_id: DB31_6306
symbol: eno
gene_biotype: protein_coding
description:
  Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.


ensembl_gene_id: DB31_6307
symbol: surE
gene_biotype: protein_coding
description:
  5-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.


ensembl_gene_id: DB31_6311
symbol: lexA
gene_biotype: protein_coding
description:
  SOS-response repressor and protease LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.


ensembl_gene_id: DB31_6336
symbol: yacG
gene_biotype: protein_coding
description:
  Hypothetical protein; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C- terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.


ensembl_gene_id: DB31_6356
symbol: pal
gene_biotype: protein_coding
description:
  Outer membrane lipoprotein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: DB31_6387
symbol: DB31_6387
gene_biotype: protein_coding
description:
  Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.


ensembl_gene_id: DB31_6409
symbol: tilS
gene_biotype: protein_coding
description:
  tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.


ensembl_gene_id: DB31_6421
symbol: glmM
gene_biotype: protein_coding
description:
  Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.


ensembl_gene_id: DB31_6423
symbol: pdxJ
gene_biotype: protein_coding
description:
  Pyridoxine 5'-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.


ensembl_gene_id: DB31_6424
symbol: acpS
gene_biotype: protein_coding
description:
  Holo-[acyl-carrier protein] synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.


ensembl_gene_id: DB31_6425
symbol: nnrD
gene_biotype: protein_coding
description:
  NAD(P)HX epimerase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.  Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epime [...]


ensembl_gene_id: DB31_6432
symbol: cheD
gene_biotype: protein_coding
description:
  Chemotaxis protein CheD; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.


ensembl_gene_id: DB31_6437
symbol: DB31_6437
gene_biotype: protein_coding
description:
  Chemotaxis protein methyltransferase CheR; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.


ensembl_gene_id: DB31_6441
symbol: DB31_6441
gene_biotype: protein_coding
description:
  Putative formate dehydrogenase oxidoreductase protein; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: DB31_6497
symbol: DB31_6497
gene_biotype: protein_coding
description:
  Malonyl CoA-acyl carrier protein transacylase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: DB31_6523
symbol: thiC
gene_biotype: protein_coding
description:
  Hydroxymethylpyrimidine phosphate synthase ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.


ensembl_gene_id: DB31_6525
symbol: DB31_6525
gene_biotype: protein_coding
description:
  Molybdenum cofactor biosynthesis protein MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.


ensembl_gene_id: DB31_6532
symbol: hisG
gene_biotype: protein_coding
description:
  ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily.


ensembl_gene_id: DB31_6533
symbol: hisD
gene_biotype: protein_coding
description:
  Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.


ensembl_gene_id: DB31_6535
symbol: hisH
gene_biotype: protein_coding
description:
  Imidazole glycerol phosphate synthase amidotransferase subunit protein; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.


ensembl_gene_id: DB31_6537
symbol: DB31_6537
gene_biotype: protein_coding
description:
  Imidazoleglycerol-phosphate dehydratase; Belongs to the imidazoleglycerol-phosphate dehydratase family.


ensembl_gene_id: DB31_6538
symbol: hisF
gene_biotype: protein_coding
description:
  Imidazole glycerol phosphate synthase cyclase subunit protein; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.


ensembl_gene_id: DB31_6570
symbol: lipA
gene_biotype: protein_coding
description:
  Lipoate synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.


ensembl_gene_id: DB31_6573
symbol: lipB
gene_biotype: protein_coding
description:
  Octanoate-[acyl-carrier-protein]-protein-N- octanoyltransferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. Belongs to the Nudix hydrolase family.


ensembl_gene_id: DB31_6575
symbol: ribA
gene_biotype: protein_coding
description:
  GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family.


ensembl_gene_id: DB31_6576
symbol: DB31_6576
gene_biotype: protein_coding
description:
  Molybdopterin biosynthesis protein MoeA; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.


ensembl_gene_id: DB31_6578
symbol: rnr
gene_biotype: protein_coding
description:
  3'-to-5' exoribonuclease RNase R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.


ensembl_gene_id: DB31_6584
symbol: mutS2
gene_biotype: protein_coding
description:
  Recombination inhibitory protein MutS2; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.


ensembl_gene_id: DB31_6589
symbol: nadD
gene_biotype: protein_coding
description:
  Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).


ensembl_gene_id: DB31_6596
symbol: ubiE-2
gene_biotype: protein_coding
description:
  Hypothetical protein; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2).


ensembl_gene_id: DB31_6670
symbol: DB31_6670
gene_biotype: protein_coding
description:
  Cation transport protein chaC; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.


ensembl_gene_id: DB31_6752
symbol: DB31_6752
gene_biotype: protein_coding
description:
  Molybdenum transport system permease protein ModB; Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: DB31_6753
symbol: DB31_6753
gene_biotype: protein_coding
description:
  Molybdenum transport ATP-binding protein ModC; Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Molybdate importer (TC 3.A.1.8) family.


ensembl_gene_id: DB31_6783
symbol: DB31_6783
gene_biotype: protein_coding
description:
  Formate dehydrogenase-O, major subunit protein; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: DB31_6813
symbol: DB31_6813
gene_biotype: protein_coding
description:
  Maltose/maltodextrin transport ATP-binding protein MalK; Belongs to the ABC transporter superfamily.


ensembl_gene_id: DB31_6829
symbol: DB31_6829
gene_biotype: protein_coding
description:
  Vitamin B12 ABC transporter, permease component BtuC; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: DB31_6881
symbol: hprK
gene_biotype: protein_coding
description:
  HPr kinase/phosphorylase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).


ensembl_gene_id: DB31_6894
symbol: DB31_6894
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate-protein phosphotransferase of PTS system; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).


ensembl_gene_id: DB31_6907
symbol: metK
gene_biotype: protein_coding
description:
  S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.


ensembl_gene_id: DB31_6910
symbol: uppP
gene_biotype: protein_coding
description:
  Undecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.


ensembl_gene_id: DB31_6935
symbol: DB31_6935
gene_biotype: protein_coding
description:
  Ribose transport system permease protein RbsC; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: DB31_6989
symbol: DB31_6989
gene_biotype: protein_coding
description:
  Ribosomal RNA large subunit methyltransferase N; Belongs to the radical SAM superfamily. RlmN family.


ensembl_gene_id: DB31_7009
symbol: fumC
gene_biotype: protein_coding
description:
  Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.


ensembl_gene_id: DB31_7022
symbol: DB31_7022
gene_biotype: protein_coding
description:
  DNA-cytosine methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.


ensembl_gene_id: DB31_7035
symbol: argB
gene_biotype: protein_coding
description:
  Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.


ensembl_gene_id: DB31_7067
symbol: mtnA
gene_biotype: protein_coding
description:
  Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).


ensembl_gene_id: DB31_7071
symbol: mtnP
gene_biotype: protein_coding
description:
  5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.


ensembl_gene_id: DB31_7074
symbol: DB31_7074
gene_biotype: protein_coding
description:
  Glycerol-3-phosphate ABC transporter, ATP-binding protein UgpC; Belongs to the ABC transporter superfamily.


ensembl_gene_id: DB31_7352
symbol: ychF
gene_biotype: protein_coding
description:
  GTP-binding and nucleic acid-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.


ensembl_gene_id: DB31_7353
symbol: atpF
gene_biotype: protein_coding
description:
  ATP synthase B chain; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family.


ensembl_gene_id: DB31_7354
symbol: atpE
gene_biotype: protein_coding
description:
  ATP synthase C chain; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.


ensembl_gene_id: DB31_7355
symbol: atpB
gene_biotype: protein_coding
description:
  ATP synthase A chain; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family.


ensembl_gene_id: DB31_7379
symbol: lgt
gene_biotype: protein_coding
description:
  Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.


ensembl_gene_id: DB31_7480
symbol: rpiA
gene_biotype: protein_coding
description:
  Ribose 5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.


ensembl_gene_id: DB31_7481
symbol: tal-2
gene_biotype: protein_coding
description:
  Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily.


ensembl_gene_id: DB31_7494
symbol: DB31_7494
gene_biotype: protein_coding
description:
  Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: DB31_7551
symbol: gyrB
gene_biotype: protein_coding
description:
  DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.


ensembl_gene_id: DB31_7597
symbol: tpm
gene_biotype: protein_coding
description:
  Thiopurine S-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.


ensembl_gene_id: DB31_7633
symbol: kdpC
gene_biotype: protein_coding
description:
  Potassium-transporting ATPase C chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.


ensembl_gene_id: DB31_7634
symbol: kdpB
gene_biotype: protein_coding
description:
  Potassium-transporting ATPase B chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.


ensembl_gene_id: DB31_7635
symbol: kdpA
gene_biotype: protein_coding
description:
  Potassium-transporting ATPase A chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane.


ensembl_gene_id: DB31_7710
symbol: DB31_7710
gene_biotype: protein_coding
description:
  Drug resistance transporter EmrB/QacA subfamily protein; Belongs to the major facilitator superfamily.


ensembl_gene_id: DB31_7787
symbol: dnaA
gene_biotype: protein_coding
description:
  Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.


ensembl_gene_id: DB31_7789
symbol: rnpA
gene_biotype: protein_coding
description:
  Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.


ensembl_gene_id: DB31_7790
symbol: DB31_7790
gene_biotype: protein_coding
description:
  Hypothetical protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family.


ensembl_gene_id: DB31_7791
symbol: yidC
gene_biotype: protein_coding
description:
  Inner membrane protein translocase component YidC, long form; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.


ensembl_gene_id: DB31_7794
symbol: mnmE
gene_biotype: protein_coding
description:
  GTPase and tRNA-U34 5-formylation enzyme TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.


ensembl_gene_id: DB31_7813
symbol: mnmG
gene_biotype: protein_coding
description:
  tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family.


ensembl_gene_id: DB31_7814
symbol: rsmG
gene_biotype: protein_coding
description:
  rRNA small subunit 7-methylguanosine (m7G) methyltransferase GidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.


ensembl_gene_id: DB31_7840
symbol: fdhD
gene_biotype: protein_coding
description:
  Formate dehydrogenase chain D; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.


ensembl_gene_id: DB31_7843
symbol: mobA
gene_biotype: protein_coding
description:
  Formate dehydrogenase chain D; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family.


ensembl_gene_id: DB31_7851
symbol: DB31_7851
gene_biotype: protein_coding
description:
  Putative short-chain oxidoreductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: DB31_7863
symbol: kynA
gene_biotype: protein_coding
description:
  Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.


ensembl_gene_id: DB31_7942
symbol: bpt
gene_biotype: protein_coding
description:
  Leucyl/phenylalanyl-tRNA--protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate. Belongs to the R-transferase family. Bpt subfamily.


ensembl_gene_id: DB31_8033
symbol: DB31_8033
gene_biotype: protein_coding
description:
  Ribonuclease E inhibitor RraA; Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.


ensembl_gene_id: DB31_8047
symbol: glmU
gene_biotype: protein_coding
description:
  N-acetylglucosamine-1-phosphate uridyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.


ensembl_gene_id: DB31_8048
symbol: glmS
gene_biotype: protein_coding
description:
  Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.


ensembl_gene_id: DB31_8058
symbol: recA
gene_biotype: protein_coding
description:
  RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.


ensembl_gene_id: DB31_8093
symbol: fmt
gene_biotype: protein_coding
description:
  Methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.


ensembl_gene_id: DB31_8095
symbol: DB31_8095
gene_biotype: protein_coding
description:
  Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.


ensembl_gene_id: DB31_8111
symbol: DB31_8111
gene_biotype: protein_coding
description:
  Anaerobic Dehydrogenase, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: DB31_8155
symbol: priA
gene_biotype: protein_coding
description:
  Helicase PriA essential for oriC/DnaA-independent DNA replication; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.


ensembl_gene_id: DB31_8160
symbol: nth
gene_biotype: protein_coding
description:
  Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.


ensembl_gene_id: DB31_8194
symbol: gatC
gene_biotype: protein_coding
description:
  Aspartyl-tRNA(Asn) amidotransferase subunit C; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family.


ensembl_gene_id: DB31_8195
symbol: gatA
gene_biotype: protein_coding
description:
  Aspartyl-tRNA(Asn) amidotransferase subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln).


ensembl_gene_id: DB31_8196
symbol: gatB
gene_biotype: protein_coding
description:
  Aspartyl-tRNA(Asn) amidotransferase subunit B; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily.


ensembl_gene_id: DB31_8202
symbol: rplU
gene_biotype: protein_coding
description:
  LSU ribosomal protein L21p; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.


ensembl_gene_id: DB31_8204
symbol: obg
gene_biotype: protein_coding
description:
  GTP-binding protein Obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.


ensembl_gene_id: DB31_8205
symbol: trmH
gene_biotype: protein_coding
description:
  tRNA (guanosine(18)-2'-O)-methyltransferase; Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.


ensembl_gene_id: DB31_8206
symbol: DB31_8206
gene_biotype: protein_coding
description:
  Outer membrane lipoprotein carrier protein LolA; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).


ensembl_gene_id: DB31_8208
symbol: rimO
gene_biotype: protein_coding
description:
  tRNA-i(6)A37 methylthiotransferase; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily.


ensembl_gene_id: DB31_8211
symbol: rnj
gene_biotype: protein_coding
description:
  Zn-dependent hydrolase; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.


ensembl_gene_id: DB31_8216
symbol: nfi
gene_biotype: protein_coding
description:
  Endonuclease V; DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.


ensembl_gene_id: DB31_8251
symbol: glgC
gene_biotype: protein_coding
description:
  Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.


ensembl_gene_id: DB31_8273
symbol: hemH
gene_biotype: protein_coding
description:
  Ferrochelatase, protoheme ferro-lyase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.


ensembl_gene_id: DB31_8277
symbol: DB31_8277
gene_biotype: protein_coding
description:
  YrdC/Sua5 family protein, required for threonylcarbamoyladenosine (t(6)A) formation in tRNA; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.


ensembl_gene_id: DB31_8306
symbol: ahpD
gene_biotype: protein_coding
description:
  Alkylhydroperoxidase protein D; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.


ensembl_gene_id: DB31_8315
symbol: lpxK
gene_biotype: protein_coding
description:
  Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).


ensembl_gene_id: DB31_8318
symbol: DB31_8318
gene_biotype: protein_coding
description:
  3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.


ensembl_gene_id: DB31_8327
symbol: lpxB
gene_biotype: protein_coding
description:
  Lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: DB31_8334
symbol: lpxA
gene_biotype: protein_coding
description:
  Acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: DB31_8335
symbol: fabZ
gene_biotype: protein_coding
description:
  (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.


ensembl_gene_id: DB31_8336
symbol: lpxD
gene_biotype: protein_coding
description:
  UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily.


ensembl_gene_id: DB31_8338
symbol: bamA
gene_biotype: protein_coding
description:
  Outer membrane protein assembly factor YaeT precursor; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: DB31_8345
symbol: DB31_8345
gene_biotype: protein_coding
description:
  Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.


ensembl_gene_id: DB31_8347
symbol: ybeY
gene_biotype: protein_coding
description:
  Metal-dependent hydrolase; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.


ensembl_gene_id: DB31_8373
symbol: nusB
gene_biotype: protein_coding
description:
  Transcription termination protein NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.


ensembl_gene_id: DB31_8374
symbol: ribH
gene_biotype: protein_coding
description:
  6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.


ensembl_gene_id: DB31_8375
symbol: ribB
gene_biotype: protein_coding
description:
  3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.


ensembl_gene_id: DB31_8377
symbol: DB31_8377
gene_biotype: protein_coding
description:
  Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.


ensembl_gene_id: DB31_8378
symbol: nrdR
gene_biotype: protein_coding
description:
  Ribonucleotide reductase transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.


ensembl_gene_id: DB31_8379
symbol: glyA
gene_biotype: protein_coding
description:
  Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.


ensembl_gene_id: DB31_8383
symbol: DB31_8383
gene_biotype: protein_coding
description:
  3-oxoacyl-[acyl-carrier protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: DB31_8385
symbol: fabH
gene_biotype: protein_coding
description:
  3-oxoacyl-[acyl-carrier-protein] synthase, KASIII; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.


ensembl_gene_id: DB31_8400
symbol: DB31_8400
gene_biotype: protein_coding
description:
  Phosphate transport system regulatory protein PhoU; Plays a role in the regulation of phosphate uptake.


ensembl_gene_id: DB31_8418
symbol: hypA
gene_biotype: protein_coding
description:
  [NiFe] hydrogenase nickel incorporation protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.


ensembl_gene_id: DB31_8419
symbol: DB31_8419
gene_biotype: protein_coding
description:
  [NiFe] hydrogenase metallocenter assembly protein HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.


ensembl_gene_id: DB31_8424
symbol: DB31_8424
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.


ensembl_gene_id: DB31_8434
symbol: ffh
gene_biotype: protein_coding
description:
  Hypothetical protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components; Belongs to  [...]


ensembl_gene_id: DB31_8451
symbol: cheB-7
gene_biotype: protein_coding
description:
  Chemotaxis response regulator protein-glutamate methylesterase CheB; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.


ensembl_gene_id: DB31_8469
symbol: rpoZ
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase omega subunit protein; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.


ensembl_gene_id: DB31_8473
symbol: groS
gene_biotype: protein_coding
description:
  Heat shock protein 60 family co-chaperone GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.


ensembl_gene_id: DB31_8480
symbol: smc
gene_biotype: protein_coding
description:
  Chromosome partition protein smc; Required for chromosome condensation and partitioning. Belongs to the SMC family.


ensembl_gene_id: DB31_8489
symbol: prfA
gene_biotype: protein_coding
description:
  Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.


ensembl_gene_id: DB31_8490
symbol: prmC
gene_biotype: protein_coding
description:
  Methylase of polypeptide chain release factor; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.


ensembl_gene_id: DB31_8491
symbol: murA
gene_biotype: protein_coding
description:
  UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.


ensembl_gene_id: DB31_8507
symbol: serC
gene_biotype: protein_coding
description:
  Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.


ensembl_gene_id: DB31_8527
symbol: pepA
gene_biotype: protein_coding
description:
  Cytosol aminopeptidase PepA; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.


ensembl_gene_id: DB31_8529
symbol: pyrF
gene_biotype: protein_coding
description:
  Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.


ensembl_gene_id: DB31_8533
symbol: lpxC
gene_biotype: protein_coding
description:
  UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family.


ensembl_gene_id: DB31_8535
symbol: ruvB
gene_biotype: protein_coding
description:
  Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.


ensembl_gene_id: DB31_8543
symbol: ruvA
gene_biotype: protein_coding
description:
  Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.


ensembl_gene_id: DB31_8544
symbol: ruvC
gene_biotype: protein_coding
description:
  Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.


ensembl_gene_id: DB31_8553
symbol: DB31_8553
gene_biotype: protein_coding
description:
  S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.


ensembl_gene_id: DB31_8587
symbol: iscS
gene_biotype: protein_coding
description:
  Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.


ensembl_gene_id: DB31_8588
symbol: DB31_8588
gene_biotype: protein_coding
description:
  Iron-sulfur cluster assembly scaffold protein IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.


ensembl_gene_id: DB31_8590
symbol: hscB
gene_biotype: protein_coding
description:
  Chaperone protein HscB; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family.


ensembl_gene_id: DB31_8591
symbol: hscA
gene_biotype: protein_coding
description:
  Chaperone protein HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.


ensembl_gene_id: DB31_8605
symbol: fni
gene_biotype: protein_coding
description:
  Isopentenyl-diphosphate delta-isomerase, FMN-dependent; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).


ensembl_gene_id: DB31_8838
symbol: rpsG
gene_biotype: protein_coding
description:
  SSU ribosomal protein S7p (S5e); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.


ensembl_gene_id: DB31_8839
symbol: rpsL
gene_biotype: protein_coding
description:
  SSU ribosomal protein S12p (S23e); Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.


ensembl_gene_id: DB31_8859
symbol: corA
gene_biotype: protein_coding
description:
  Magnesium and cobalt transport protein CorA; Mediates influx of magnesium ions. Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.


ensembl_gene_id: DB31_8870
symbol: thiG
gene_biotype: protein_coding
description:
  Thiazole biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.


ensembl_gene_id: DB31_8883
symbol: DB31_8883
gene_biotype: protein_coding
description:
  ABC transporter involved in cytochrome c biogenesis, ATPase component CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.


ensembl_gene_id: DB31_8884
symbol: DB31_8884
gene_biotype: protein_coding
description:
  ABC transporter involved in cytochrome c biogenesis, CcmB subunit protein; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family.


ensembl_gene_id: DB31_8887
symbol: DB31_8887
gene_biotype: protein_coding
description:
  Cytochrome c-type biogenesis protein CcmE, heme chaperone; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.


ensembl_gene_id: DB31_8894
symbol: DB31_8894
gene_biotype: protein_coding
description:
  UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase; Belongs to the DegT/DnrJ/EryC1 family.


ensembl_gene_id: DB31_8896
symbol: DB31_8896
gene_biotype: protein_coding
description:
  Hypothetical protein; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family.


ensembl_gene_id: DB31_8928
symbol: DB31_8928
gene_biotype: protein_coding
description:
  GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.


ensembl_gene_id: DB31_8946
symbol: greB
gene_biotype: protein_coding
description:
  Transcription elongation factor GreB; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. Belongs to the GreA/GreB family. GreB subfamily.


ensembl_gene_id: DB31_9032
symbol: DB31_9032
gene_biotype: protein_coding
description:
  Lactam utilization protein LamB; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.


ensembl_gene_id: DB31_9093
symbol: coaX
gene_biotype: protein_coding
description:
  Pantothenate kinase type III protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.


ensembl_gene_id: DB31_9094
symbol: birA
gene_biotype: protein_coding
description:
  Biotin-protein ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.


