# pathwayInfo

id: SM00460
description: Transglutaminase/protease-like homologues
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00460
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM00460_Transglutaminase/protease-like_homologues


id: SM00464
description: Found in ATP-dependent protease La (LON)
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00464
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM00464_Found_in_ATP-dependent_protease_La_(LON)


id: SM00471
description: Metal dependent phosphohydrolases with conserved HD motif.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00471
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM00471_Metal_dependent_phosphohydrolases_with_conserved_HD_motif.


id: SM00479
description: Exonuclease domain in DNA-polymerase alpha and epsilon chain, ribonuclease T and other exonucleases
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00479
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM00479_Exonuclease_domain_in_DNA-polymerase_alpha_and_epsilon_chain,_ribonuclease_T_and_other_exonucleases


id: SM00493
description: Topoisomerases, DnaG-type primases, OLD family nucleases and RecR proteins
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00493
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM00493_Topoisomerases,_DnaG-type_primases,_OLD_family_nucleases_and_RecR_proteins


id: SM00508
description: Cysteine-rich motif following a subset of SET domains
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00508
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM00508_Cysteine-rich_motif_following_a_subset_of_SET_domains


id: SM00513
description: Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00513
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM00513_Putative_DNA-binding_(bihelical)_motif_predicted_to_be_involved_in_chromosomal_organisation


id: SM00525
description: Iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3)
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00525
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM00525_Iron-sulpphur_binding_domain_in_DNA-(apurinic_or_apyrimidinic_site)_lyase_(subfamily_of_ENDO3)


id: SM00530
description: Helix-turn-helix XRE-family like proteins
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00530
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM00530_Helix-turn-helix_XRE-family_like_proteins


id: SM00533
description: DNA-binding domain of DNA mismatch repair MUTS family
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00533
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM00533_DNA-binding_domain_of_DNA_mismatch_repair_MUTS_family


id: SM00534
description: ATPase domain of DNA mismatch repair MUTS family
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00534
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM00534_ATPase_domain_of_DNA_mismatch_repair_MUTS_family


id: SM00558
description: A domain family that is part of the cupin metalloenzyme superfamily.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00558
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM00558_A_domain_family_that_is_part_of_the_cupin_metalloenzyme_superfamily.


id: SM00562
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00562
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM00562_These_are_enzymes_that_catalyze_nonsubstrate_specific_conversions_of_nucleoside_diphosphates_to_nucleoside_triphosphates._These_enzymes_play_important_roles_in_bacterial_growth,_signal_transduction_and_pathogenicity.

description:
  These are enzymes that catalyze nonsubstrate specific conversions of nucleoside diphosphates to nucleoside triphosphates. These enzymes play important roles in bacterial growth, signal transduction and pathogenicity.


id: SM00670
description: Large family of predicted nucleotide-binding domains
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00670
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM00670_Large_family_of_predicted_nucleotide-binding_domains


id: SM00702
description: Prolyl 4-hydroxylase alpha subunit homologues.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00702
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM00702_Prolyl_4-hydroxylase_alpha_subunit_homologues.


id: SM00729
description: Elongator protein 3, MiaB family, Radical SAM
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00729
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM00729_Elongator_protein_3,_MiaB_family,_Radical_SAM


id: SM00738
description: In Spt5p, this domain may confer affinity for Spt4p. It possesses a RNP-like fold.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00738
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM00738_In_Spt5p,_this_domain_may_confer_affinity_for_Spt4p._It_possesses_a_RNP-like_fold.


id: SM00752
description: Horizontally Transferred TransMembrane Domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00752
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM00752_Horizontally_Transferred_TransMembrane_Domain


id: SM00754
description: A domain in the BMP inhibitor chordin and in microbial proteins.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00754
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM00754_A_domain_in_the_BMP_inhibitor_chordin_and_in_microbial_proteins.


id: SM00758
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00758
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM00758_Domain_in_bacterial_beta-glucosidases_other_glycosidases,_glycosyltransferases,_proteases,_amidases,_yeast_adhesins,_and_bacterial_toxins.

description:
  Domain in bacterial beta-glucosidases other glycosidases, glycosyltransferases, proteases, amidases, yeast adhesins, and bacterial toxins.


id: SM00760
description: Bacterial dnaA protein helix-turn-helix domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00760
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM00760_Bacterial_dnaA_protein_helix-turn-helix_domain


id: SM00769
description: Water Stress and Hypersensitive response
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00769
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM00769_Water_Stress_and_Hypersensitive_response


id: SM00810
description: Alpha-amylase C-terminal beta-sheet domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00810
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM00810_Alpha-amylase_C-terminal_beta-sheet_domain


id: SM00822
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00822
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM00822_This_enzymatic_domain_is_part_of_bacterial_polyketide_synthases_and_catalyses_the_first_step_in_the_reductive_modification_of_the_beta-carbonyl_centres_in_the_growing_polyketide_chain._It_uses_NADPH_to_reduce_the_keto_group_to_a_hydroxy_group.

description:
  This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group.


id: SM00827
description: Acyl transferase domain in polyketide synthase (PKS) enzymes.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00827
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM00827_Acyl_transferase_domain_in_polyketide_synthase_(PKS)_enzymes.


id: SM00837
description: Rare lipoprotein A (RlpA)-like double-psi beta-barrel
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00837
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM00837_Rare_lipoprotein_A_(RlpA)-like_double-psi_beta-barrel


id: SM00839
description: Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00839
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM00839_Glutamate/Leucine/Phenylalanine/Valine_dehydrogenase


id: SM00840
description: This DALR domain is found in cysteinyl-tRNA-synthetases.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00840
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM00840_This_DALR_domain_is_found_in_cysteinyl-tRNA-synthetases.


id: SM00843
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00843
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM00843_This_domain_directs_oriented_DNA_translocation_and_forms_a_winged_helix_structure._Mutated_proteins_with_substitutions_in_the_FtsK_gamma_DNA-recognition_helix_are_impaired_in_DNA_binding.

description:
  This domain directs oriented DNA translocation and forms a winged helix structure. Mutated proteins with substitutions in the FtsK gamma DNA-recognition helix are impaired in DNA binding.


id: SM00846
description: Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00846
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM00846_Glyceraldehyde_3-phosphate_dehydrogenase,_NAD_binding_domain


id: SM00847
description: Helicase associated domain (HA2) Add an annotation
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00847
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM00847_Helicase_associated_domain_(HA2)__Add_an_annotation


id: SM00854
description: Bacterial capsule synthesis protein PGA_cap
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00854
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM00854_Bacterial_capsule_synthesis_protein_PGA_cap


id: SM00858
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00858
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM00858_This_domain_family_includes_a_range_of_different_proteins._Such_as_antifreeze_proteins_and_flagellar_FlgA_proteins,_and_CpaB_pilus_proteins.

description:
  This domain family includes a range of different proteins. Such as antifreeze proteins and flagellar FlgA proteins, and CpaB pilus proteins.


id: SM00859
description: Semialdehyde dehydrogenase, NAD binding domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00859
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM00859_Semialdehyde_dehydrogenase,_NAD_binding_domain


id: SM00861
description: Transketolase, pyrimidine binding domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00861
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM00861_Transketolase,_pyrimidine_binding_domain


id: SM00862
description: Transcriptional regulatory protein, C terminal
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00862
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM00862_Transcriptional_regulatory_protein,_C_terminal


id: SM00863
description: Threonyl and Alanyl tRNA synthetase second additional domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00863
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM00863_Threonyl_and_Alanyl_tRNA_synthetase_second_additional_domain


id: SM00870
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00870
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM00870_Asparaginase,_which_is_found_in_various_plant,_animal_and_bacterial_cells,_catalyses_the_deamination_of_asparagine_to_yield_aspartic_acid_and_an_ammonium_ion,_resulting_in_a_depletion_of_free_circulatory_asparagine_in_plasma_PUBMED:3026924._The_...

description:
  Asparaginase, which is found in various plant, animal and bacterial cells, catalyses the deamination of asparagine to yield aspartic acid and an ammonium ion, resulting in a depletion of free circulatory asparagine in plasma PUBMED:3026924. The ...


id: SM00876
description: Biotin and Thiamin Synthesis associated domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00876
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM00876_Biotin_and_Thiamin_Synthesis_associated_domain


id: SM00877
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00877
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM00877_Bacterial_microcompartments_are_primitive_organelles_composed_entirely_of_protein_subunits._The_prototypical_bacterial_microcompartment_is_the_carboxysome,_a_protein_shell_for_sequestering_carbon_fixation_reactions._These_proteins_for_hexameric_...

description:
  Bacterial microcompartments are primitive organelles composed entirely of protein subunits. The prototypical bacterial microcompartment is the carboxysome, a protein shell for sequestering carbon fixation reactions. These proteins for hexameric ...


id: SM00880
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00880
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM00880_The_CHAD_domain_is_an_alpha-helical_domain_functionally_associated_with_some_members_of_the_adenylate_cyclase_family_._It_has_conserved_histidines_that_may_chelate_metals.

description:
  The CHAD domain is an alpha-helical domain functionally associated with some members of the adenylate cyclase family . It has conserved histidines that may chelate metals.


id: SM00896
description: Ferredoxin-fold anticodon binding domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00896
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM00896_Ferredoxin-fold_anticodon_binding_domain


id: SM00898
description: Formamidopyrimidine-DNA glycosylase N-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00898
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM00898_Formamidopyrimidine-DNA_glycosylase_N-terminal_domain


id: SM00901
description: This domain contains a conserved N-terminal (F/Y)RG motif. It is functionally uncharacterised.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00901
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM00901_This_domain_contains_a_conserved_N-terminal_(F/Y)RG_motif._It_is_functionally_uncharacterised.


id: SM00922
description: Mandelate racemase / muconate lactonizing enzyme, C-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00922
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM00922_Mandelate_racemase_/_muconate_lactonizing_enzyme,_C-terminal_domain


id: SM00926
description: Molybdopterin oxidoreductase Fe4S4 domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00926
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM00926_Molybdopterin_oxidoreductase_Fe4S4_domain


id: SM00928
description: NADH-ubiquinone oxidoreductase-F iron-sulfur binding region
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00928
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM00928_NADH-ubiquinone_oxidoreductase-F_iron-sulfur_binding_region


id: SM00929
description: NADH-ubiquinone oxidoreductase-G iron-sulfur binding region
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00929
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM00929_NADH-ubiquinone_oxidoreductase-G_iron-sulfur_binding_region


id: SM00934
description: Orotidine 5-phosphate decarboxylase / HUMPS family
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00934
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM00934_Orotidine_5-phosphate_decarboxylase_/_HUMPS_family


id: SM00937
description: This domain is found in peptide chain release factors.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00937
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM00937_This_domain_is_found_in_peptide_chain_release_factors.


id: SM00939
description: X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00939
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM00939_X-Pro_dipeptidyl-peptidase_C-terminal_non-catalytic_domain


id: SM00941
description: Pyrimidine nucleoside phosphorylase C-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00941
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM00941_Pyrimidine_nucleoside_phosphorylase_C-terminal_domain


id: SM00948
description: Proteasome subunit A N-terminal signature Add an annotation
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00948
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM00948_Proteasome_subunit_A_N-terminal_signature__Add_an_annotation


id: SM00955
description: This domain is the catalytic domain of ribonuclease II.PUBMED:16806266
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00955
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM00955_This_domain_is_the_catalytic_domain_of_ribonuclease_II.PUBMED:16806266


id: SM00959
description: Rho termination factor, N-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00959
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM00959_Rho_termination_factor,_N-terminal_domain


id: SM00963
description: SRP54-type protein, helical bundle domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00963
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM00963_SRP54-type_protein,_helical_bundle_domain


id: SM00965
description: Secretin and TonB N terminus short domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00965
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM00965_Secretin_and_TonB_N_terminus_short_domain


id: SM00967
description: RNA 2-O ribose methyltransferase substrate binding
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00967
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM00967_RNA_2-O_ribose_methyltransferase_substrate_binding


id: SM00978
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00978
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM00978_Tim44_is_an_essential_component_of_the_machinery_that_mediates_the_translocation_of_nuclear-encoded_proteins_across_the_mitochondrial_inner_membrane_PUBMED:10430866._Tim44_is_thought_to_bind_phospholipids_of_the_mitochondrial_inner_membrane_both_by_...

description:
  Tim44 is an essential component of the machinery that mediates the translocation of nuclear-encoded proteins across the mitochondrial inner membrane PUBMED:10430866. Tim44 is thought to bind phospholipids of the mitochondrial inner membrane both by ...


id: SM00981
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00981
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM00981_The_THUMP_domain_is_named_after_after_thiouridine_synthases,_methylases_and_PSUSs_PUBMED:11295541._The_THUMP_domain_consists_of_about_110_amino_acid_residues._The_structure_of_ThiI_reveals_that_the_THUMP_has_a_fold_unlike_that_of_previously_...

description:
  The THUMP domain is named after after thiouridine synthases, methylases and PSUSs PUBMED:11295541. The THUMP domain consists of about 110 amino acid residues. The structure of ThiI reveals that the THUMP has a fold unlike that of previously ...


id: SM00982
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00982
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM00982_This_domain_is_found_in_proteins_necessary_for_strand-specific_repair_in_DNA_such_as_TRCF_in_Escherichia_coli._A_lesion_in_the_template_strand_blocks_the_RNA_polymerase_complex_(RNAP)._The_RNAP-DNA-RNA_complex_is_specifically_recognised_by_the_...

description:
  This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli. A lesion in the template strand blocks the RNA polymerase complex (RNAP). The RNAP-DNA-RNA complex is specifically recognised by the ...


id: SM00987
description: UreE urease accessory protein, C-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00987
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM00987_UreE_urease_accessory_protein,_C-terminal_domain


id: SM00989
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00989
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM00989_The_V4R_(vinyl_4_reductase)_domain_is_a_predicted_small_molecular_binding_domain,_that_may_bind_to_hydrocarbons.

description:
  The V4R (vinyl 4 reductase) domain is a predicted small molecular binding domain, that may bind to hydrocarbons.


id: SM00997
description: S-adenosyl-L-homocysteine hydrolase, NAD binding domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00997
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM00997_S-adenosyl-L-homocysteine_hydrolase,_NAD_binding_domain


id: SM01002
description: Alanine dehydrogenase/PNT, C-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01002
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM01002_Alanine_dehydrogenase/PNT,_C-terminal_domain


id: SM01003
description: Alanine dehydrogenase/PNT, N-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01003
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM01003_Alanine_dehydrogenase/PNT,_N-terminal_domain


id: SM01007
description: Class II Aldolase and Adducin N-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01007
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM01007_Class_II_Aldolase_and_Adducin_N-terminal_domain


id: SM01008
description: Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01008
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM01008_Aldehyde_oxidase_and_xanthine_dehydrogenase,_a/b_hammerhead_domain


id: SM01049
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01049
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM01049_Cache_is_an_extracellular_domain_that_is_predicted_to_have_a_role_in_small-molecule_recognition_in_a_wide_range_of_proteins,_including_the_animal_dihydropyridine-sensitive_voltage-gated_Ca2+_channel

description:
  Cache is an extracellular domain that is predicted to have a role in small-molecule recognition in a wide range of proteins, including the animal dihydropyridine-sensitive voltage-gated Ca2+ channel


id: SM01060
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01060
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM01060_Catalases_are_antioxidant_enzymes_that_catalyse_the_conversion_of_hydrogen_peroxide_to_water_and_molecular_oxygen,_serving_to_protect_cells_from_its_toxic_effects_PUBMED:11351128._Hydrogen_peroxide_is_produced_as_a_consequence_of_oxidative_cellular_...

description:
  Catalases are antioxidant enzymes that catalyse the conversion of hydrogen peroxide to water and molecular oxygen, serving to protect cells from its toxic effects PUBMED:11351128. Hydrogen peroxide is produced as a consequence of oxidative cellular ...


id: SM01079
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01079
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM01079_This_domain_is_found_in_the_extracellular_portion_of_receptor-like_proteins_-_such_as_serine/threonine_kinases_and_adenylyl_cyclases_PUBMED:11590000,_PUBMED:11590001._Predicted_to_be_a_ligand_binding_domain_PUBMED:11590000.

description:
  This domain is found in the extracellular portion of receptor-like proteins - such as serine/threonine kinases and adenylyl cyclases PUBMED:11590000, PUBMED:11590001. Predicted to be a ligand binding domain PUBMED:11590000.


id: SM01080
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01080
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM01080_CHASE2_is_an_extracellular_sensory_domain,_which_is_present_in_various_classes_of_transmembrane_receptors_that_are_parts_of_signal_transduction_pathways_in_bacteria._Specifically,_CHASE2_domains_are_found_in_histidine_kinases,_adenylate_cyclases,_...

description:
  CHASE2 is an extracellular sensory domain, which is present in various classes of transmembrane receptors that are parts of signal transduction pathways in bacteria. Specifically, CHASE2 domains are found in histidine kinases, adenylate cyclases, ...


id: SM01086
description: C-terminal, D2-small domain, of ClpB protein
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01086
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM01086_C-terminal,_D2-small_domain,_of_ClpB_protein


id: SM01092
description: CO dehydrogenase flavoprotein C-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01092
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM01092_CO_dehydrogenase_flavoprotein_C-terminal_domain


id: SM01096
description: Carbamoyl-phosphate synthetase large chain, oligomerisation domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01096
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM01096_Carbamoyl-phosphate_synthetase_large_chain,_oligomerisation_domain


id: SM01097
description: Carbamoyl-phosphate synthase small chain, CPSase domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01097
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM01097_Carbamoyl-phosphate_synthase_small_chain,_CPSase_domain


id: SM01103
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01103
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM01103_Escherichia_coli_YhbY_is_associated_with_pre-50S_ribosomal_subunits,_which_implies_a_function_in_ribosome_assembly._GFP_fused_to_a_single-domain_CRM_protein_from_maize_localises_to_the_nucleolus,_suggesting_that_an_analogous_activity_may_have_been_...

description:
  Escherichia coli YhbY is associated with pre-50S ribosomal subunits, which implies a function in ribosome assembly. GFP fused to a single-domain CRM protein from maize localises to the nucleolus, suggesting that an analogous activity may have been ...


id: SM01144
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01144
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM01144_This_presumed_domain_is_found_in_bacterial_and_eukaryotic_proteins._Its_function_is_unknown._The_domain_contains_multiple_conserved_motifs_including_a_DTXW_motif_that_this_domain_has_been_named_after.

description:
  This presumed domain is found in bacterial and eukaryotic proteins. Its function is unknown. The domain contains multiple conserved motifs including a DTXW motif that this domain has been named after.


id: SM01150
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01150
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM01150_This_domain_is_found_in_a_variety_of_bacterial_and_fungal_hypothetical_proteins_of_unknown_function._The_structure_of_this_domain_has_been_solved_by_structural_genomics._The_structure_implies_a_zinc-binding_function,_so_it_is_a_putative_metal_...

description:
  This domain is found in a variety of bacterial and fungal hypothetical proteins of unknown function. The structure of this domain has been solved by structural genomics. The structure implies a zinc-binding function, so it is a putative metal ...


id: SM01204
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01204
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM01204_The_FIST_C_domain_is_a_novel_sensory_domain,_which_is_present_in_signal_transduction_proteins_from_Bacteria,_Archaea_and_Eukarya._Chromosomal_proximity_of_FIST-encoding_genes_to_those_coding_for_proteins_involved_in_amino_acid_metabolism_and_...

description:
  The FIST C domain is a novel sensory domain, which is present in signal transduction proteins from Bacteria, Archaea and Eukarya. Chromosomal proximity of FIST-encoding genes to those coding for proteins involved in amino acid metabolism and ...


id: SM01209
description: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01209
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM01209_Phosphoribosylglycinamide_synthetase,_ATP-grasp_(A)_domain


id: SM01210
description: Phosphoribosylglycinamide synthetase, C domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01210
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM01210_Phosphoribosylglycinamide_synthetase,_C_domain


id: SM01211
description: CobB/CobQ-like glutamine amidotransferase domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01211
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM01211_CobB/CobQ-like_glutamine_amidotransferase_domain


id: SM01231
description: Signal transducing histidine kinase, homodimeric domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01231
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM01231_Signal_transducing_histidine_kinase,_homodimeric_domain


id: SM01232
description: Formamidopyrimidine-DNA glycosylase H2TH domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01232
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM01232_Formamidopyrimidine-DNA_glycosylase_H2TH_domain


id: SM01234
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01234
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM01234_This_domain_has_haemolytic_activity_(PMID:19306042)._It_is_found_in_short_(73-103_amino_acid)_proteins_and_contains_three_conserved_cysteine_residues.

description:
  This domain has haemolytic activity (PMID:19306042). It is found in short (73-103 amino acid) proteins and contains three conserved cysteine residues.


id: SM01322
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01322
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM01322_This_family_consists_of_several_hypothetical_bacterial_proteins_of_around_180_residues_in_length_which_are_often_known_as_YaeQ._YaeQ_is_homologous_to_RfaH,_a_specialised_transcription_elongation_protein._YaeQ_is_known_to_compensate_for_loss_of_RfaH_...

description:
  This family consists of several hypothetical bacterial proteins of around 180 residues in length which are often known as YaeQ. YaeQ is homologous to RfaH, a specialised transcription elongation protein. YaeQ is known to compensate for loss of RfaH ...


id: SM01324
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01324
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM01324_This_presumed_extracellular_domain_is_about_70_amino_acids_in_length._It_is_named_YARHG_after_a_conserved_motif_in_the_sequence._This_domain_is_associated_with_peptidases_and_bacterial_kinase_proteins._Its_molecular_function_is_unknown.

description:
  This presumed extracellular domain is about 70 amino acids in length. It is named YARHG after a conserved motif in the sequence. This domain is associated with peptidases and bacterial kinase proteins. Its molecular function is unknown.


id: SM01325
description: This family of proteins has no known function.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01325
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM01325_This_family_of_proteins_has_no_known_function.


id: SM01329
description: Isocitrate/isopropylmalate dehydrogenase
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01329
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM01329_Isocitrate/isopropylmalate_dehydrogenase


id: SM01340
description: DNA mismatch repair protein, C-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01340
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM01340_DNA_mismatch_repair_protein,_C-terminal_domain


id: SM01350
description: 6-phosphogluconate dehydrogenase, C-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01350
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM01350_6-phosphogluconate_dehydrogenase,_C-terminal_domain


id: SM01382
description: Ribosomal Proteins L2, C-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01382
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM01382_Ribosomal_Proteins_L2,_C-terminal_domain


id: SM01383
description: Ribosomal Proteins L2, RNA binding domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01383
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM01383_Ribosomal_Proteins_L2,_RNA_binding_domain


id: SM01390
description: Ribosomal protein S4/S9 N-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01390
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM01390_Ribosomal_protein_S4/S9_N-terminal_domain


id: SM01400
description: N-terminal domain of ribose phosphate pyrophosphokinase
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01400
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM01400_N-terminal_domain_of_ribose_phosphate_pyrophosphokinase


id: SM01419
description: Alpha-macro-globulin thiol-ester bond-forming region
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01419
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM01419_Alpha-macro-globulin_thiol-ester_bond-forming_region


id: SM01433
description: PD-(D/E)XK nuclease transposase sub-family
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01433
name:
  Protein Domains (SMART).STRING_v12.0_394096_STRINGid_SM01433_PD-(D/E)XK_nuclease_transposase_sub-family


