# geneInfo

ensembl_gene_id: Spro_2304
symbol: Spro_2304
gene_biotype: protein_coding
description:
  PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: vei:Veis_4630 glyoxalase/bleomycin resistance protein/dioxygenase.


ensembl_gene_id: Spro_2306
symbol: Spro_2306
gene_biotype: protein_coding
description:
  Peptidyl-dipeptidase Dcp; PFAM: peptidase M3A and M3B thimet/oligopeptidase F; KEGG: xac:XAC0249 peptidyl-dipeptidase.


ensembl_gene_id: Spro_2308
symbol: Spro_2308
gene_biotype: protein_coding
description:
  N-carbamoylsarcosine amidase; PFAM: isochorismatase hydrolase; KEGG: ppf:Pput_1896 isochorismatase hydrolase.


ensembl_gene_id: Spro_2309
symbol: maiA
gene_biotype: protein_coding
description:
  Asp/Glu racemase; Catalyzes cis-trans isomerization of the C2-C3 double bond in maleate to yield fumarate.


ensembl_gene_id: Spro_2313
symbol: Spro_2313
gene_biotype: protein_coding
description:
  Transcriptional regulator, MarR family; PFAM: regulatory protein MarR; KEGG: reu:Reut_A2508 regulatory protein, MarR.


ensembl_gene_id: Spro_2314
symbol: Spro_2314
gene_biotype: protein_coding
description:
  PFAM: ferredoxin; [2Fe-2S]-binding domain protein; KEGG: ppf:Pput_1890 (2Fe-2S)-binding domain protein.


ensembl_gene_id: Spro_2315
symbol: Spro_2315
gene_biotype: protein_coding
description:
  PFAM: cytochrome c class I; aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; KEGG: ppu:PP_3948 aldehyde dehydrogenase family protein, putative/cytochrome c family protein, putative.


ensembl_gene_id: Spro_2317
symbol: Spro_2317
gene_biotype: protein_coding
description:
  ABC transporter-related protein; PFAM: ABC transporter transmembrane region; ABC transporter related; peptidase C39 bacteriocin processing; SMART: AAA ATPase; KEGG: bps:BPSL3093 colicin V processing peptidase.


ensembl_gene_id: Spro_2319
symbol: Spro_2319
gene_biotype: protein_coding
description:
  PFAM: aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; KEGG: swi:Swit_3976 aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding.


ensembl_gene_id: Spro_2320
symbol: Spro_2320
gene_biotype: protein_coding
description:
  PFAM: ferredoxin; [2Fe-2S]-binding domain protein; KEGG: bch:Bcen2424_4406 (2Fe-2S)-binding domain protein.


ensembl_gene_id: Spro_2321
symbol: Spro_2321
gene_biotype: protein_coding
description:
  Gluconate 2-dehydrogenase (acceptor); PFAM: cytochrome c class I; KEGG: bch:Bcen2424_5380 cytochrome c, class I.


ensembl_gene_id: Spro_2322
symbol: Spro_2322
gene_biotype: protein_coding
description:
  Oxalate decarboxylase; PFAM: Cupin domain protein; Cupin 2 conserved barrel domain protein; KEGG: plu:plu2325 putative oxalate decarboxylase.


ensembl_gene_id: Spro_2323
symbol: Spro_2323
gene_biotype: protein_coding
description:
  TIGRFAM: PTS system, glucose subfamily, IIA subunit; PTS system, beta-glucoside-specific IIABC subunit; PFAM: sugar-specific permease EIIA 1 domain; phosphotransferase system PTS EIIB protein; phosphotransferase system EIIC; KEGG: eca:ECA0860 PTS system, IIabc component.


ensembl_gene_id: Spro_2324
symbol: Spro_2324
gene_biotype: protein_coding
description:
  PFAM: glycoside hydrolase family 1; KEGG: eca:ECA0859 beta-glucosidase; Belongs to the glycosyl hydrolase 1 family.


ensembl_gene_id: Spro_2325
symbol: Spro_2325
gene_biotype: protein_coding
description:
  Transcriptional antiterminator, BglG; PFAM: CAT RNA-binding domain protein; PRD domain protein; KEGG: eca:ECA0858 putative beta-glucoside operon antiterminator.


ensembl_gene_id: Spro_2326
symbol: Spro_2326
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: mms:mma_1186 transcriptional regulator, LysR family.


ensembl_gene_id: Spro_2333
symbol: Spro_2333
gene_biotype: protein_coding
description:
  PFAM: glucose-methanol-choline oxidoreductase; FAD dependent oxidoreductase; KEGG: bch:Bcen2424_4610 glucose-methanol-choline oxidoreductase.


ensembl_gene_id: Spro_2335
symbol: Spro_2335
gene_biotype: protein_coding
description:
  Gluconate 2-dehydrogenase (acceptor); PFAM: cytochrome c class I; KEGG: bch:Bcen2424_4612 cytochrome c, class I.


ensembl_gene_id: Spro_2336
symbol: Spro_2336
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF6 transmembrane; KEGG: yen:YE1742 putative inner membrane protein.


ensembl_gene_id: Spro_2337
symbol: Spro_2337
gene_biotype: protein_coding
description:
  Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: yen:YE1743 putative AraC-family transcriptional regulatory protein.


ensembl_gene_id: Spro_2341
symbol: Spro_2341
gene_biotype: protein_coding
description:
  KEGG: eca:ECA2248 putative mannosyl-3-phosphoglycerate phosphatase; TIGRFAM: HAD-superfamily hydrolase, subfamily IIB; mannosyl-3-phosphoglycerate phosphatase family; PFAM: sucrose-6F-phosphate phosphohydrolase; Haloacid dehalogenase domain protein hydrolase type 3.


ensembl_gene_id: Spro_2346
symbol: ddpX
gene_biotype: protein_coding
description:
  Peptidase M15D vanX D-ala-D-ala dipeptidase; Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.


ensembl_gene_id: Spro_2347
symbol: Spro_2347
gene_biotype: protein_coding
description:
  PFAM: extracellular solute-binding protein family 5; KEGG: ecs:ECs2091 putative hemin-binding lipoprotein.


ensembl_gene_id: Spro_2348
symbol: Spro_2348
gene_biotype: protein_coding
description:
  PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sbo:SBO_1571 putative transport system permease protein.


ensembl_gene_id: Spro_2349
symbol: Spro_2349
gene_biotype: protein_coding
description:
  PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ecs:ECs2089 putative transport protein.


ensembl_gene_id: Spro_2350
symbol: Spro_2350
gene_biotype: protein_coding
description:
  KEGG: ecj:JW1479 D-Ala-D-Ala transporter subunit; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; Belongs to the ABC transporter superfamily.


ensembl_gene_id: Spro_2351
symbol: Spro_2351
gene_biotype: protein_coding
description:
  Oligopeptide/dipeptide ABC transporter, ATPase subunit; KEGG: ecs:ECs2087 putative ATP-binding component of a transport system; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; Belongs to the ABC transporter superfamily.


ensembl_gene_id: Spro_2352
symbol: Spro_2352
gene_biotype: protein_coding
description:
  acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: Spro_2353
symbol: Spro_2353
gene_biotype: protein_coding
description:
  PFAM: major facilitator superfamily MFS_1; KEGG: bxe:Bxe_B0529 major facilitator superfamily (MFS) efflux pump.


ensembl_gene_id: Spro_2354
symbol: Spro_2354
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: rpe:RPE_2870 transcriptional regulator, LysR family.


ensembl_gene_id: Spro_2361
symbol: Spro_2361
gene_biotype: protein_coding
description:
  ABC transporter-related protein; PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: eca:ECA0854 ABC transporter, ATP-binding protein.


ensembl_gene_id: Spro_2362
symbol: Spro_2362
gene_biotype: protein_coding
description:
  TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eca:ECA0855 ABC transporter permease protein.


ensembl_gene_id: Spro_2363
symbol: Spro_2363
gene_biotype: protein_coding
description:
  PFAM: extracellular solute-binding protein family 3; KEGG: eca:ECA0856 ABC transporter, periplasmic binding protein.


ensembl_gene_id: Spro_2368
symbol: Spro_2368
gene_biotype: protein_coding
description:
  PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: atc:AGR_L_1189 hypothetical protein.


ensembl_gene_id: Spro_2371
symbol: Spro_2371
gene_biotype: protein_coding
description:
  PFAM: iron-containing alcohol dehydrogenase; 3-dehydroquinate synthase; KEGG: eca:ECA2718 putative iron-containing alcohol dehydrogenase.


ensembl_gene_id: Spro_2372
symbol: Spro_2372
gene_biotype: protein_coding
description:
  PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; NmrA family protein; Male sterility domain; KR domain protein; KEGG: ppu:PP_2986 oxidoreductase, putative.


ensembl_gene_id: Spro_2383
symbol: Spro_2383
gene_biotype: protein_coding
description:
  PFAM: CopG domain protein DNA-binding domain protein; KEGG: csa:Csal_1436 helix-turn-helix protein, CopG.


ensembl_gene_id: Spro_2385
symbol: Spro_2385
gene_biotype: protein_coding
description:
  PFAM: Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA/FabZ; KEGG: asa:ASA_3149 (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase.


ensembl_gene_id: Spro_2388
symbol: Spro_2388
gene_biotype: protein_coding
description:
  PFAM: membrane attack complex component/perforin/complement C9; KEGG: cmi:CMM_2382 hypothetical protein, putative perforin.


ensembl_gene_id: Spro_2389
symbol: Spro_2389
gene_biotype: protein_coding
description:
  KEGG: ecv:APECO1_2952 arsenate reductase ArsC; TIGRFAM: arsenate reductase; PFAM: arsenate reductase and related.


ensembl_gene_id: Spro_2390
symbol: Spro_2390
gene_biotype: protein_coding
description:
  Arsenical pump membrane protein; Involved in arsenical resistance. Thought to form the channel of an arsenite pump; Belongs to the ArsB family.


ensembl_gene_id: Spro_2391
symbol: Spro_2391
gene_biotype: protein_coding
description:
  Transcriptional regulator, ArsR family; PFAM: regulatory protein ArsR; KEGG: eca:ECA1605 arsenical resistance operon repressor.


ensembl_gene_id: Spro_2392
symbol: Spro_2392
gene_biotype: protein_coding
description:
  PAS modulated sigma54 specific transcriptional regulator, Fis family; PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; GAF domain protein; ATPase associated with various cellular activities AAA_5; SMART: PAS domain containing protein; AAA ATPase; KEGG: psp:PSPPH_2337 sigma-54 dependent transcriptional regulator.


ensembl_gene_id: Spro_2393
symbol: Spro_2393
gene_biotype: protein_coding
description:
  Inositol 2-dehydrogenase; PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: pst:PSPTO_3047 myo-inositol 2-dehydrogenase, putative.


ensembl_gene_id: Spro_2394
symbol: Spro_2394
gene_biotype: protein_coding
description:
  PFAM: Xylose isomerase domain protein TIM barrel; KEGG: psp:PSPPH_2335 AP endonuclease, family 2 superfamily; Belongs to the hyi family.


ensembl_gene_id: Spro_2397
symbol: Spro_2397
gene_biotype: protein_coding
description:
  PFAM: extracellular solute-binding protein family 3; KEGG: yen:YE2044 amino acid-binding periplasmic protein precursor.


ensembl_gene_id: Spro_2398
symbol: Spro_2398
gene_biotype: protein_coding
description:
  TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: yen:YE2043 amino acid transport system permease protein.


ensembl_gene_id: Spro_2399
symbol: Spro_2399
gene_biotype: protein_coding
description:
  TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: cvi:CV_3087 histidine transport system membrane protein M.


ensembl_gene_id: Spro_2400
symbol: Spro_2400
gene_biotype: protein_coding
description:
  PFAM: regulatory protein AsnC/Lrp family; KEGG: yen:YE2040 probable leucine-responsive regulatory protein.


ensembl_gene_id: Spro_2402
symbol: Spro_2402
gene_biotype: protein_coding
description:
  ABC transporter-related protein; PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: maq:Maqu_0009 ABC transporter related.


ensembl_gene_id: Spro_2403
symbol: Spro_2403
gene_biotype: protein_coding
description:
  PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: stm:STM1567 alcohol dehydrogenase.


ensembl_gene_id: Spro_2406
symbol: Spro_2406
gene_biotype: protein_coding
description:
  PFAM: fimbrial biogenesis outer membrane usher protein; KEGG: bch:Bcen2424_1755 fimbrial biogenesis outer membrane usher protein.


ensembl_gene_id: Spro_2408
symbol: Spro_2408
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF1120; KEGG: bch:Bcen2424_1753 protein of unknown function DUF1120.


ensembl_gene_id: Spro_2410
symbol: Spro_2410
gene_biotype: protein_coding
description:
  PFAM: aldehyde dehydrogenase; KEGG: pae:PA4022 probable aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: Spro_2411
symbol: Spro_2411
gene_biotype: protein_coding
description:
  GAF modulated sigma54 specific transcriptional regulator, Fis family; PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; GAF domain protein; SMART: AAA ATPase; KEGG: kpn:KPN_02992 putative helix-turn-helix, fis-type.


ensembl_gene_id: Spro_2412
symbol: Spro_2412
gene_biotype: protein_coding
description:
  PFAM: extracellular solute-binding protein family 3; KEGG: eca:ECA2156 ABC transporter, substrate binding protein.


ensembl_gene_id: Spro_2413
symbol: Spro_2413
gene_biotype: protein_coding
description:
  Heavy metal translocating P-type ATPase; TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper ion binding protein; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; Heavy metal transport/detoxification protein; E1-E2 ATPase-associated domain protein; KEGG: atc:AGR_C_2202 copper-transporting ATPase.


ensembl_gene_id: Spro_2414
symbol: Spro_2414
gene_biotype: protein_coding
description:
  Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; PAS fold-4 domain protein; KEGG: acb:A1S_1949 putative diguanylate cyclase/phosphodiesterase.


ensembl_gene_id: Spro_2416
symbol: Spro_2416
gene_biotype: protein_coding
description:
  TAP domain protein; PFAM: alpha/beta hydrolase fold; TAP domain protein; KEGG: atu:Atu2171 hydrolase.


ensembl_gene_id: Spro_2417
symbol: Spro_2417
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: kpn:KPN_03313 putative bacterial regulatory protein, LysR; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Spro_2419
symbol: Spro_2419
gene_biotype: protein_coding
description:
  TIGRFAM: 2,4-diaminobutyrate 4-transaminase; PFAM: aminotransferase class-III; KEGG: eca:ECA2243 diaminobutyrate--2-oxoglutarate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: Spro_2420
symbol: Spro_2420
gene_biotype: protein_coding
description:
  Diguanylate cyclase with PAS/PAC sensor; KEGG: aha:AHA_3686 histidine kinase-response regulator hybrid protein; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; GAF domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.


ensembl_gene_id: Spro_2422
symbol: Spro_2422
gene_biotype: protein_coding
description:
  TIGRFAM: high-affinity nickel-transporter; KEGG: plu:plu2170 putative high-affinity nickel-transport protein; Belongs to the NiCoT transporter (TC 2.A.52) family.


ensembl_gene_id: Spro_2423
symbol: Spro_2423
gene_biotype: protein_coding
description:
  (NiFe) hydrogenase maturation protein HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.


ensembl_gene_id: Spro_2424
symbol: Spro_2424
gene_biotype: protein_coding
description:
  TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: kpn:KPN_02090 formate dehydrogenase H, selenopolypeptide subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: Spro_2425
symbol: Spro_2425
gene_biotype: protein_coding
description:
  PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: stm:STM2843 electron transport protein (FeS senter) from formate to hydrogen.


ensembl_gene_id: Spro_2426
symbol: Spro_2426
gene_biotype: protein_coding
description:
  TIGRFAM: hydrogenase maturation protease; hydrogenase maturation protease HycI; hydrogenase maturation peptidase superfamily; PFAM: peptidase M52 hydrogen uptake protein; KEGG: sdy:SDY_2914 HycI.


ensembl_gene_id: Spro_2427
symbol: Spro_2427
gene_biotype: protein_coding
description:
  PFAM: formate hydrogenlyase maturation HycH; KEGG: kpn:KPN_03055 processing of HycE (part of the FHL complex).


ensembl_gene_id: Spro_2428
symbol: Spro_2428
gene_biotype: protein_coding
description:
  PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; KEGG: ent:Ent638_3192 NADH ubiquinone oxidoreductase, 20 kDa subunit.


ensembl_gene_id: Spro_2429
symbol: Spro_2429
gene_biotype: protein_coding
description:
  PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: ecv:APECO1_3805 formate hydrogenlyase complex iron-sulfur protein.


ensembl_gene_id: Spro_2430
symbol: Spro_2430
gene_biotype: protein_coding
description:
  PFAM: NADH-ubiquinone oxidoreductase chain 49kDa; NADH dehydrogenase (ubiquinone) 30 kDa subunit; KEGG: stm:STM2849 hydrogenase 3 large subunit.


ensembl_gene_id: Spro_2431
symbol: Spro_2431
gene_biotype: protein_coding
description:
  PFAM: respiratory-chain NADH dehydrogenase subunit 1; KEGG: kpn:KPN_03059 hydrogenase 3, membrane subunit (part of FHL complex).


ensembl_gene_id: Spro_2432
symbol: Spro_2432
gene_biotype: protein_coding
description:
  NADH dehydrogenase (quinone); PFAM: NADH/Ubiquinone/plastoquinone (complex I); KEGG: spt:SPA2709 NADH dehydrogenase subunit N.


ensembl_gene_id: Spro_2433
symbol: Spro_2433
gene_biotype: protein_coding
description:
  PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: stm:STM2852 hydrogenase-3 iron-sulfur subunit.


ensembl_gene_id: Spro_2435
symbol: hypA
gene_biotype: protein_coding
description:
  Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.


ensembl_gene_id: Spro_2436
symbol: Spro_2436
gene_biotype: protein_coding
description:
  TIGRFAM: hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K; KEGG: stm:STM2855 hydrogenase-3 accessory protein, assembly of metallocenter.


ensembl_gene_id: Spro_2437
symbol: Spro_2437
gene_biotype: protein_coding
description:
  TIGRFAM: hydrogenase assembly chaperone hypC/hupF; PFAM: hydrogenase expression/formation protein (HUPF/HYPC); KEGG: yen:YE2796 putative hydrogenase isoenzymes formation protein.


ensembl_gene_id: Spro_2438
symbol: Spro_2438
gene_biotype: protein_coding
description:
  TIGRFAM: hydrogenase expression/formation protein HypD; PFAM: hydrogenase formation HypD protein; KEGG: yen:YE3602 hydrogenase isoenzymes formation protein; Belongs to the HypD family.


ensembl_gene_id: Spro_2439
symbol: Spro_2439
gene_biotype: protein_coding
description:
  TIGRFAM: hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein; AIR synthase related protein domain protein; KEGG: sec:SC2791 putative hydrogenase expression/formation protein.


ensembl_gene_id: Spro_2440
symbol: Spro_2440
gene_biotype: protein_coding
description:
  Transcriptional regulator, NifA subfamily, Fis Family; PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; GAF domain protein; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: sbo:SBO_2789 formate hydrogen-lyase transcriptional activator for FdhF, hyc and hyp operons.


ensembl_gene_id: Spro_2443
symbol: Spro_2443
gene_biotype: protein_coding
description:
  KEGG: pfl:PFL_2568 sensory box transcriptional regulator, LuxR family; TIGRFAM: PAS sensor protein; PFAM: regulatory protein LuxR; PAS fold-3 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.


ensembl_gene_id: Spro_2444
symbol: Spro_2444
gene_biotype: protein_coding
description:
  TIGRFAM: Dyp-type peroxidase family; PFAM: Dyp-type peroxidase; KEGG: aor:AO090102000042 predicted iron-dependent peroxidase.


ensembl_gene_id: Spro_2448
symbol: Spro_2448
gene_biotype: protein_coding
description:
  PFAM: NUDIX hydrolase; KEGG: mms:mma_2565 MutT/NUDIX-family hydrolase; Belongs to the Nudix hydrolase family.


ensembl_gene_id: Spro_2450
symbol: Spro_2450
gene_biotype: protein_coding
description:
  TIGRFAM: gluconate transporter; PFAM: Gluconate transporter; Citrate transporter; KEGG: spt:SPA3652 DsdX permease.


ensembl_gene_id: Spro_2451
symbol: Spro_2451
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; TIGRFAM: D-serine deaminase transcriptional activator; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: stm:STM3800 transcriptional activator.


ensembl_gene_id: Spro_2452
symbol: Spro_2452
gene_biotype: protein_coding
description:
  PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: rso:RSp0505 2-hydroxyacid dehydrogenase.


ensembl_gene_id: Spro_2454
symbol: Spro_2454
gene_biotype: protein_coding
description:
  TIGRFAM: TonB-dependent copper receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: plu:plu3519 unnamed protein product; highly similar to outer membrane receptor protein.


ensembl_gene_id: Spro_2455
symbol: Spro_2455
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ent:Ent638_0049 transcriptional regulator, LysR family.


ensembl_gene_id: Spro_2456
symbol: Spro_2456
gene_biotype: protein_coding
description:
  PFAM: major facilitator superfamily MFS_1; KEGG: ent:Ent638_0048 major facilitator superfamily MFS_1.


ensembl_gene_id: Spro_2458
symbol: Spro_2458
gene_biotype: protein_coding
description:
  PFAM: C4-dicarboxylate transporter/malic acid transport protein; KEGG: stm:STM1609 TDT family, K+-tellurite ethidium and proflavin transport protein.


ensembl_gene_id: Spro_2459
symbol: Spro_2459
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: bpl:BURPS1106A_A0260 transcriptional regulator, LysR family.


ensembl_gene_id: Spro_2461
symbol: Spro_2461
gene_biotype: protein_coding
description:
  Alkylglycerone-phosphate synthase; PFAM: FAD linked oxidase domain protein; KEGG: ecv:APECO1_3760 putative FAD containing dehydrogenase.


ensembl_gene_id: Spro_2462
symbol: Spro_2462
gene_biotype: protein_coding
description:
  PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: ecs:ECs3630 putative oxidoreductase.


ensembl_gene_id: Spro_2465
symbol: Spro_2465
gene_biotype: protein_coding
description:
  PFAM: glycerol-3-phosphate responsive antiterminator; KEGG: ecs:ECs3623 putative anti-terminator regulatory protein.


ensembl_gene_id: Spro_2466
symbol: Spro_2466
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: yps:YPTB2501 putative LysR-family transcriptional regulator.


ensembl_gene_id: Spro_2467
symbol: Spro_2467
gene_biotype: protein_coding
description:
  PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: ypp:YPDSF_1874 transporter protein.


ensembl_gene_id: Spro_2470
symbol: Spro_2470
gene_biotype: protein_coding
description:
  TIGRFAM: succinic semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase; KEGG: yen:YE3793 succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: Spro_2471
symbol: Spro_2471
gene_biotype: protein_coding
description:
  PFAM: GCN5-related N-acetyltransferase; regulatory protein MarR; KEGG: pfl:PFL_3482 transcriptional regulator, MarR family/acetyl transferase, GNAT family.


ensembl_gene_id: Spro_2472
symbol: Spro_2472
gene_biotype: protein_coding
description:
  PFAM: amino acid permease-associated region; KEGG: plu:plu3105 unnamed protein product; similar to D-serine/D-alanine/glycine transporter.


ensembl_gene_id: Spro_2473
symbol: Spro_2473
gene_biotype: protein_coding
description:
  PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; KEGG: kpn:KPN_01492 putative glutamic dehyrogenase-like protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.


ensembl_gene_id: Spro_2474
symbol: Spro_2474
gene_biotype: protein_coding
description:
  PFAM: AMP-dependent synthetase and ligase; KEGG: rha:RHA1_ro03779 long-chain-fatty-acid--CoA ligase.


ensembl_gene_id: Spro_2475
symbol: Spro_2475
gene_biotype: protein_coding
description:
  TIGRFAM: intracellular protease, PfpI family; PFAM: ThiJ/PfpI domain protein; KEGG: kpn:KPN_01321 putative intracellular protease/amidase.


ensembl_gene_id: Spro_2477
symbol: Spro_2477
gene_biotype: protein_coding
description:
  TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein; KEGG: yen:YE0445 probable outer membrane efflux lipoprotein.


ensembl_gene_id: Spro_2478
symbol: Spro_2478
gene_biotype: protein_coding
description:
  TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: yen:YE0444 multidrug efflux protein.


ensembl_gene_id: Spro_2479
symbol: Spro_2479
gene_biotype: protein_coding
description:
  TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: ypi:YpsIP31758_3586 efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: Spro_2480
symbol: Spro_2480
gene_biotype: protein_coding
description:
  TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: ent:Ent638_0043 drug resistance transporter, EmrB/QacA subfamily.


ensembl_gene_id: Spro_2482
symbol: Spro_2482
gene_biotype: protein_coding
description:
  Agmatine deiminase; PFAM: Porphyromonas-type peptidyl-arginine deiminase; KEGG: pen:PSEEN4632 peptidylarginine deiminase, PPADH family; Belongs to the agmatine deiminase family.


ensembl_gene_id: Spro_2483
symbol: Spro_2483
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: pfo:Pfl_2369 transcriptional regulator, LysR family.


ensembl_gene_id: Spro_2484
symbol: Spro_2484
gene_biotype: protein_coding
description:
  KEGG: pap:PSPA7_4047 gamma-glutamyltransferase; TIGRFAM: gamma-glutamyltransferase; PFAM: gamma-glutamyltranspeptidase.


ensembl_gene_id: Spro_2487
symbol: Spro_2487
gene_biotype: protein_coding
description:
  Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; KEGG: eca:ECA3650 putative DNA-binding protein.


ensembl_gene_id: Spro_2489
symbol: Spro_2489
gene_biotype: protein_coding
description:
  TIGRFAM: transposase, IS605 OrfB family; PFAM: putative transposase IS891/IS1136/IS1341 family; transposase IS605 OrfB; KEGG: shn:Shewana3_4234 transposase, IS605 OrfB family.


ensembl_gene_id: Spro_2490
symbol: Spro_2490
gene_biotype: protein_coding
description:
  Gluconate 2-dehydrogenase (acceptor); PFAM: cytochrome c class I; KEGG: pae:PA1600 probable cytochrome c.


ensembl_gene_id: Spro_2491
symbol: Spro_2491
gene_biotype: protein_coding
description:
  PFAM: aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; KEGG: pae:PA1601 probable aldehyde dehydrogenase.


ensembl_gene_id: Spro_2493
symbol: Spro_2493
gene_biotype: protein_coding
description:
  TIGRFAM: cysteine desulfurase, SufS subfamily; PFAM: aminotransferase class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: azo:azo0369 probable cysteine desulphurase; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: Spro_2497
symbol: Spro_2497
gene_biotype: protein_coding
description:
  PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: ypp:YPDSF_1946 D-isomer specific 2-hydroxyacid dehydrogenase family protein.


ensembl_gene_id: Spro_2498
symbol: Spro_2498
gene_biotype: protein_coding
description:
  PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: yps:YPTB2567 putative 2-ketogluconate transporter, ACS family-MFS superfamily.


ensembl_gene_id: Spro_2499
symbol: Spro_2499
gene_biotype: protein_coding
description:
  Transcriptional regulator, RpiR family; PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); KEGG: yen:YE1415 putative LacI-family regulatory protein.


ensembl_gene_id: Spro_2500
symbol: Spro_2500
gene_biotype: protein_coding
description:
  PFAM: glycoside hydrolase family 1; KEGG: yen:YE1417 6-phospho-beta-glucosidase; Belongs to the glycosyl hydrolase 1 family.


ensembl_gene_id: Spro_2501
symbol: Spro_2501
gene_biotype: protein_coding
description:
  TIGRFAM: protocatechuate 3,4-dioxygenase, beta subunit; PFAM: intradiol ring-cleavage dioxygenase; KEGG: kpn:KPN_01948 putative oxidoreductase.


ensembl_gene_id: Spro_2502
symbol: Spro_2502
gene_biotype: protein_coding
description:
  Protocatechuate 3,4-dioxygenase, alpha subunit; KEGG: kpn:KPN_01949 intradiol ring-cleavage dioxygenase; TIGRFAM: protocatechuate 3,4-dioxygenase, alpha subunit; PFAM: intradiol ring-cleavage dioxygenase.


ensembl_gene_id: Spro_2503
symbol: Spro_2503
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: stm:STM1625 putative transcriptional regulator.


ensembl_gene_id: Spro_2504
symbol: Spro_2504
gene_biotype: protein_coding
description:
  KEGG: kpn:KPN_01543 putative 4-carboxymuconolactone decarboxylase; TIGRFAM: 4-carboxymuconolactone decarboxylase; PFAM: Carboxymuconolactone decarboxylase.


ensembl_gene_id: Spro_2505
symbol: Spro_2505
gene_biotype: protein_coding
description:
  TIGRFAM: 3-carboxy-cis,cis-muconate cycloisomerase; PFAM: fumarate lyase; KEGG: kpn:KPN_01541 putative fumarate lyase.


ensembl_gene_id: Spro_2506
symbol: Spro_2506
gene_biotype: protein_coding
description:
  4-hydroxybenzoate 3-monooxygenase; PFAM: monooxygenase FAD-binding; KEGG: rme:Rmet_5490 monooxygenase, FAD-binding.


ensembl_gene_id: Spro_2507
symbol: Spro_2507
gene_biotype: protein_coding
description:
  TIGRFAM: benzoate transport; PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: kpn:KPN_03917 putative permeases of the major facilitator superfamily.


ensembl_gene_id: Spro_2512
symbol: Spro_2512
gene_biotype: protein_coding
description:
  PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: kpn:KPN_00382 general substrate transporter.


ensembl_gene_id: Spro_2514
symbol: Spro_2514
gene_biotype: protein_coding
description:
  Transcriptional regulator, IclR family; TIGRFAM: beta-ketoadipate pathway transcriptional regulators, PcaR/PcaU/PobR family; PFAM: regulatory protein IclR; Transcriptional regulator IclR; KEGG: kpn:KPN_01537 putative transcriptional repressor (IclR family).


ensembl_gene_id: Spro_2515
symbol: dsdA
gene_biotype: protein_coding
description:
  KEGG: yen:YE0800 D-serine dehydratase; TIGRFAM: D-serine ammonia-lyase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit.


ensembl_gene_id: Spro_2516
symbol: Spro_2516
gene_biotype: protein_coding
description:
  PFAM: 3-demethylubiquinone-9 3-methyltransferase; KEGG: mes:Meso_0138 3-demethylubiquinone-9 3-methyltransferase.


ensembl_gene_id: Spro_2517
symbol: Spro_2517
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF1428; KEGG: ent:Ent638_0929 protein of unknown function DUF1428.


ensembl_gene_id: Spro_2518
symbol: Spro_2518
gene_biotype: protein_coding
description:
  TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: pen:PSEEN2260 diguanylate cyclase (GGDEF) domain.


ensembl_gene_id: Spro_2521
symbol: Spro_2521
gene_biotype: protein_coding
description:
  PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; KEGG: pin:Ping_2381 alpha-D-1,4-glucosidase.


ensembl_gene_id: Spro_2522
symbol: Spro_2522
gene_biotype: protein_coding
description:
  PFAM: ABC transporter related; TOBE domain protein; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: rso:RSc2140 probable sugar ATP-binding ABC transporter protein.


ensembl_gene_id: Spro_2523
symbol: Spro_2523
gene_biotype: protein_coding
description:
  PFAM: glycoside hydrolase family 4; KEGG: mag:amb2735 alpha-galactosidase/6-phospho-beta-glucosidase.


ensembl_gene_id: Spro_2524
symbol: Spro_2524
gene_biotype: protein_coding
description:
  PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bms:BRA0306 sugar ABC transporter, permease protein.


ensembl_gene_id: Spro_2525
symbol: Spro_2525
gene_biotype: protein_coding
description:
  PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: hch:HCH_00203 ABC-type sugar transport system, permease components.


ensembl_gene_id: Spro_2526
symbol: Spro_2526
gene_biotype: protein_coding
description:
  PFAM: extracellular solute-binding protein family 1; KEGG: csa:Csal_0258 extracellular solute-binding protein, family 1.


ensembl_gene_id: Spro_2527
symbol: Spro_2527
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ppr:PBPRB0712 hypothetical transcriptional regulator.


ensembl_gene_id: Spro_2528
symbol: Spro_2528
gene_biotype: protein_coding
description:
  PFAM: MscS Mechanosensitive ion channel; KEGG: yen:YE0322 putative inner-membrane transport protein.


ensembl_gene_id: Spro_2529
symbol: Spro_2529
gene_biotype: protein_coding
description:
  ABC transporter-related protein; PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ent:Ent638_2048 ABC transporter related.


ensembl_gene_id: Spro_2530
symbol: Spro_2530
gene_biotype: protein_coding
description:
  TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; KEGG: nha:Nham_1450 cation diffusion facilitator family transporter; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.


ensembl_gene_id: Spro_2531
symbol: Spro_2531
gene_biotype: protein_coding
description:
  PFAM: CBS domain containing protein; MgtE integral membrane region; KEGG: kpn:KPN_03856 putative Mg/Co/Ni transporter MgtE.


ensembl_gene_id: Spro_2532
symbol: Spro_2532
gene_biotype: protein_coding
description:
  DNA (cytosine-5-)-methyltransferase; PFAM: transposase IS605 OrfB; KEGG: sfv:SFV_1675 putative virulence protein.


ensembl_gene_id: Spro_2534
symbol: Spro_2534
gene_biotype: protein_coding
description:
  PFAM: extracellular solute-binding protein family 1; KEGG: yen:YE1241 iron(III)-binding periplasmic protein.


ensembl_gene_id: Spro_2535
symbol: Spro_2535
gene_biotype: protein_coding
description:
  PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: yen:YE1240 iron(III)-transport system permease.


ensembl_gene_id: Spro_2536
symbol: fbpC
gene_biotype: protein_coding
description:
  ABC transporter-related protein; Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import. Responsible for energy coupling to the transport system.


ensembl_gene_id: Spro_2537
symbol: fusA
gene_biotype: protein_coding
description:
  Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...]


ensembl_gene_id: Spro_2540
symbol: Spro_2540
gene_biotype: protein_coding
description:
  Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein AraC type; AraC protein arabinose-binding/dimerisation; KEGG: eca:ECA1518 AraC-family transcriptional regulator.


ensembl_gene_id: Spro_2542
symbol: Spro_2542
gene_biotype: protein_coding
description:
  PFAM: Alpha/beta hydrolase fold-3 domain protein; KEGG: bur:Bcep18194_B3090 esterase/lipase/thioesterase.


ensembl_gene_id: Spro_2544
symbol: Spro_2544
gene_biotype: protein_coding
description:
  PFAM: AP endonuclease 2 domain protein; Xylose isomerase domain protein TIM barrel; KEGG: pfl:PFL_3507 AP endonuclease family 2 protein.


ensembl_gene_id: Spro_2547
symbol: kup
gene_biotype: protein_coding
description:
  K potassium transporter; Responsible for the low-affinity transport of potassium into the cell, with the probable concomitant uptake of protons (symport system); Belongs to the HAK/KUP transporter (TC 2.A.72) family.


ensembl_gene_id: Spro_2548
symbol: Spro_2548
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: bam:Bamb_3505 transcriptional regulator, LysR family.


ensembl_gene_id: Spro_2549
symbol: Spro_2549
gene_biotype: protein_coding
description:
  PFAM: inner-membrane translocator; KEGG: bxe:Bxe_A0822 ABC branched chain amino acid family transporter, inner membrane subunit; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: Spro_2550
symbol: Spro_2550
gene_biotype: protein_coding
description:
  PFAM: inner-membrane translocator; KEGG: rso:RSc2439 probable amino-acid transmembrane ABC transporter protein; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: Spro_2551
symbol: Spro_2551
gene_biotype: protein_coding
description:
  ABC transporter-related protein; PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: rme:Rmet_2864 ABC transporter-related protein.


ensembl_gene_id: Spro_2552
symbol: Spro_2552
gene_biotype: protein_coding
description:
  ABC transporter-related protein; PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: bte:BTH_I0788 branched-chain amino acid ABC transporter, ATP-binding protein; Belongs to the ABC transporter superfamily.


ensembl_gene_id: Spro_2553
symbol: Spro_2553
gene_biotype: protein_coding
description:
  PFAM: Extracellular ligand-binding receptor; KEGG: bam:Bamb_3506 extracellular ligand-binding receptor.


ensembl_gene_id: Spro_2555
symbol: Spro_2555
gene_biotype: protein_coding
description:
  KEGG: bxe:Bxe_A1427 amidase, hydantoinase/carbamoylase; TIGRFAM: amidase, hydantoinase/carbamoylase family; PFAM: peptidase M20; peptidase dimerisation domain protein.


ensembl_gene_id: Spro_2558
symbol: Spro_2558
gene_biotype: protein_coding
description:
  PFAM: Mg2 transporter protein CorA family protein; KEGG: kpn:KPN_01510 putative Mg2+ and Co2+ transporters.


ensembl_gene_id: Spro_2560
symbol: Spro_2560
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF344; KEGG: bur:Bcep18194_B1834 protein of unknown function DUF344.


ensembl_gene_id: Spro_2561
symbol: Spro_2561
gene_biotype: protein_coding
description:
  PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; KEGG: bxe:Bxe_A1545 peptidase S11, D-alanyl-D-alanine carboxypeptidase 1; Belongs to the peptidase S11 family.


ensembl_gene_id: Spro_2563
symbol: Spro_2563
gene_biotype: protein_coding
description:
  PFAM: regulatory protein GntR HTH; aminotransferase class I and II; KEGG: aav:Aave_0017 transcriptional regulator, GntR family.


ensembl_gene_id: Spro_2566
symbol: Spro_2566
gene_biotype: protein_coding
description:
  TIGRFAM: pyridoxal kinase; PFAM: Phosphomethylpyrimidine kinase type-1; KEGG: kpn:KPN_02766 pyridoxine kinase; Belongs to the pyridoxine kinase family.


ensembl_gene_id: Spro_2567
symbol: ycgR
gene_biotype: protein_coding
description:
  YcgR family protein; Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility.


ensembl_gene_id: Spro_2571
symbol: Spro_2571
gene_biotype: protein_coding
description:
  PFAM: extracellular solute-binding protein family 1; KEGG: cpr:CPR_0476 ABC transporter, substrate-binding protein.


ensembl_gene_id: Spro_2572
symbol: Spro_2572
gene_biotype: protein_coding
description:
  PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bcz:BCZK1635 sugar ABC transporter, permease.


ensembl_gene_id: Spro_2573
symbol: Spro_2573
gene_biotype: protein_coding
description:
  PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bcz:BCZK1636 sugar ABC transporter, permease.


ensembl_gene_id: Spro_2574
symbol: Spro_2574
gene_biotype: protein_coding
description:
  PFAM: ABC transporter related; TOBE domain protein; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: amt:Amet_0894 ABC transporter related.


ensembl_gene_id: Spro_2577
symbol: Spro_2577
gene_biotype: protein_coding
description:
  Transcriptional regulator, DeoR family; PFAM: regulatory protein DeoR; Helix-turn-helix type 11 domain protein; KEGG: plu:plu0832 putative aga operon transcriptional repressor.


ensembl_gene_id: Spro_2578
symbol: Spro_2578
gene_biotype: protein_coding
description:
  TIGRFAM: Sugar isomerase AgaS; PFAM: sugar isomerase (SIS); KEGG: plu:plu0834 putative tagatose-6-phosphate ketose/aldose isomerase.


ensembl_gene_id: Spro_2579
symbol: Spro_2579
gene_biotype: protein_coding
description:
  Class II aldolase, tagatose bisphosphate family; KEGG: plu:plu0839 tagatose-bisphosphate aldolase GatY; TIGRFAM: ketose-bisphosphate aldolase; class II aldolase, tagatose bisphosphate family; PFAM: ketose-bisphosphate aldolase class-II.


ensembl_gene_id: Spro_2581
symbol: Spro_2581
gene_biotype: protein_coding
description:
  methylated-DNA--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.


ensembl_gene_id: Spro_2582
symbol: Spro_2582
gene_biotype: protein_coding
description:
  Transcriptional regulator, Crp/Fnr family; PFAM: cyclic nucleotide-binding; regulatory protein Crp; KEGG: ent:Ent638_1853 putative transcriptional regulator, Crp/Fnr family.


ensembl_gene_id: Spro_2584
symbol: Spro_2584
gene_biotype: protein_coding
description:
  NAD(P)(+) transhydrogenase (AB-specific); The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.


ensembl_gene_id: Spro_2585
symbol: Spro_2585
gene_biotype: protein_coding
description:
  NAD(P) transhydrogenase, alpha subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the AlaDH/PNT family.


ensembl_gene_id: Spro_2587
symbol: Spro_2587
gene_biotype: protein_coding
description:
  TIGRFAM: arginine/ornithine antiporter; PFAM: amino acid permease-associated region; KEGG: ypi:YpsIP31758_1828 putative arginine/ornithine antiporter ArcD.


ensembl_gene_id: Spro_2590
symbol: Spro_2590
gene_biotype: protein_coding
description:
  Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: yen:YE2083 two-component regulatory system, response regulator protein.


ensembl_gene_id: Spro_2591
symbol: Spro_2591
gene_biotype: protein_coding
description:
  Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: ypi:YpsIP31758_1825 sensor protein RstB.


ensembl_gene_id: Spro_2592
symbol: Spro_2592
gene_biotype: protein_coding
description:
  Carboxypeptidase Taq; Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.


ensembl_gene_id: Spro_2595
symbol: Spro_2595
gene_biotype: protein_coding
description:
  KEGG: ypi:YpsIP31758_1815 ATP-dependent helicase HrpA; TIGRFAM: ATP-dependent helicase HrpA; PFAM: helicase domain protein; helicase-associated domain protein; protein of unknown function DUF1605; SMART: AAA ATPase; DEAD-like helicases.


ensembl_gene_id: Spro_2600
symbol: Spro_2600
gene_biotype: protein_coding
description:
  PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: ypi:YpsIP31758_1808 fermentative lactate dehydrogenase.


ensembl_gene_id: Spro_2601
symbol: Spro_2601
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF306 Meta and HslJ; KEGG: ypi:YpsIP31758_1807 heat shock protein HslJ.


ensembl_gene_id: Spro_2603
symbol: Spro_2603
gene_biotype: protein_coding
description:
  PFAM: small multidrug resistance protein; KEGG: yen:YE2101 quaternary ammonium compound-resistance protein.


ensembl_gene_id: Spro_2604
symbol: Spro_2604
gene_biotype: protein_coding
description:
  PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: yen:YE2102 putative pyruvate-flavodoxin oxidoreductase.


ensembl_gene_id: Spro_2605
symbol: Spro_2605
gene_biotype: protein_coding
description:
  PFAM: peptidase S24 and S26 domain protein; KEGG: stm:STM1998 error-prone repair: SOS-response transcriptional repressors (LexA homologs, RecA-mediated autopeptidases).


ensembl_gene_id: Spro_2606
symbol: Spro_2606
gene_biotype: protein_coding
description:
  DNA-directed DNA polymerase; PFAM: UMUC domain protein DNA-repair protein; KEGG: ecc:c1632 umuC protein; Belongs to the DNA polymerase type-Y family.


ensembl_gene_id: Spro_2607
symbol: ttcA
gene_biotype: protein_coding
description:
  PP-loop domain protein; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.


ensembl_gene_id: Spro_2608
symbol: Spro_2608
gene_biotype: protein_coding
description:
  PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: psa:PST_3709 lactoylglutathione lyase.


ensembl_gene_id: Spro_2609
symbol: Spro_2609
gene_biotype: protein_coding
description:
  PFAM: Mg2 transporter protein CorA family protein; KEGG: yen:YE2107 CorA-like Mg2+ transporter protein.


ensembl_gene_id: Spro_2611
symbol: Spro_2611
gene_biotype: protein_coding
description:
  PFAM: extracellular solute-binding protein family 5; KEGG: yen:YE2110 putative periplasmic murein peptide-binding protein.


ensembl_gene_id: Spro_2613
symbol: Spro_2613
gene_biotype: protein_coding
description:
  PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: pap:PSPA7_4415 alcohol dehydrogenase, zinc-binding.


ensembl_gene_id: Spro_2615
symbol: Spro_2615
gene_biotype: protein_coding
description:
  PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: yps:YPTB2260 putative mandelate racemase / muconate lactonizing protein.


ensembl_gene_id: Spro_2616
symbol: tpx
gene_biotype: protein_coding
description:
  Redoxin domain protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily.


ensembl_gene_id: Spro_2617
symbol: Spro_2617
gene_biotype: protein_coding
description:
  Transcriptional regulator, TyrR; KEGG: ypi:YpsIP31758_1794 transcriptional regulatory protein TyrR; TIGRFAM: PAS sensor protein; PFAM: sigma-54 factor interaction domain-containing protein; amino acid-binding ACT domain protein; PAS fold domain protein; SMART: PAS domain containing protein; AAA ATPase.


ensembl_gene_id: Spro_2619
symbol: Spro_2619
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF463 YcjX family protein; KEGG: yen:YE2118 hypothetical protein.


ensembl_gene_id: Spro_2624
symbol: Spro_2624
gene_biotype: protein_coding
description:
  TIGRFAM: shock protein A; PFAM: PspA/IM30 family protein; KEGG: ypi:YpsIP31758_1786 phage shock protein A.


ensembl_gene_id: Spro_2625
symbol: Spro_2625
gene_biotype: protein_coding
description:
  Sigma54 specific transcriptional regulator, Fis family; KEGG: yen:YE2122 psp operon transcriptional activator; TIGRFAM: Transcriptional activator PspF; PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; SMART: AAA ATPase.


ensembl_gene_id: Spro_2626
symbol: Spro_2626
gene_biotype: protein_coding
description:
  PFAM: cobalamin synthesis protein P47K; cobalamin synthesis CobW domain protein; KEGG: csa:Csal_0192 cobalamin synthesis protein, P47K.


ensembl_gene_id: Spro_2629
symbol: Spro_2629
gene_biotype: protein_coding
description:
  PFAM: extracellular solute-binding protein family 5; KEGG: yen:YE2125 peptide transport periplasmic protein precursor.


ensembl_gene_id: Spro_2630
symbol: Spro_2630
gene_biotype: protein_coding
description:
  PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: yen:YE2126 peptide transport system permease protein.


ensembl_gene_id: Spro_2631
symbol: Spro_2631
gene_biotype: protein_coding
description:
  PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: yen:YE2127 peptide transport system permease protein.


ensembl_gene_id: Spro_2632
symbol: Spro_2632
gene_biotype: protein_coding
description:
  Oligopeptide/dipeptide ABC transporter, ATPase subunit; KEGG: yen:YE2128 peptide transport system ATP-binding protein; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; Belongs to the ABC transporter superfamily.


ensembl_gene_id: Spro_2633
symbol: Spro_2633
gene_biotype: protein_coding
description:
  ABC transporter-related protein; PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ypi:YpsIP31758_1780 peptide ABC transporter, ATP-binding protein SapF.


ensembl_gene_id: Spro_2634
symbol: Spro_2634
gene_biotype: protein_coding
description:
  TIGRFAM: uncharacterized peroxidase-related enzyme; PFAM: Carboxymuconolactone decarboxylase; KEGG: ypi:YpsIP31758_1779 hypothetical protein.


ensembl_gene_id: Spro_2635
symbol: Spro_2635
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: yen:YE2132 LysR-family transcriptional regulatory protein.


ensembl_gene_id: Spro_2636
symbol: Spro_2636
gene_biotype: protein_coding
description:
  Serine-type D-Ala-D-Ala carboxypeptidase; PFAM: beta-lactamase; peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; Penicillin-binding protein 5 domain protein; KEGG: ent:Ent638_2578 serine-type D-Ala-D-Ala carboxypeptidase; Belongs to the peptidase S11 family.


ensembl_gene_id: Spro_2637
symbol: Spro_2637
gene_biotype: protein_coding
description:
  TIGRFAM: oxidoreductase alpha (molybdopterin) subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; KEGG: yen:YE1983 putative oxidoreductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: Spro_2638
symbol: rnb
gene_biotype: protein_coding
description:
  Exoribonuclease II; Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction.


ensembl_gene_id: Spro_2640
symbol: Spro_2640
gene_biotype: protein_coding
description:
  Putative transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.


ensembl_gene_id: Spro_2641
symbol: Spro_2641
gene_biotype: protein_coding
description:
  KEGG: yen:YE0645 putative pyruvate formate-lyase 3 activating enzyme; TIGRFAM: glycyl-radical enzyme activating protein family; PFAM: Radical SAM domain protein.


ensembl_gene_id: Spro_2642
symbol: Spro_2642
gene_biotype: protein_coding
description:
  Pyruvate formate-lyase; KEGG: yen:YE0646 putative formate acetyltransferase; TIGRFAM: pyruvate formate-lyase; PFAM: formate C-acetyltransferase glycine radical; pyruvate formate-lyase PFL.


ensembl_gene_id: Spro_2643
symbol: Spro_2643
gene_biotype: protein_coding
description:
  Transcriptional regulator, DeoR family; PFAM: regulatory protein DeoR; Helix-turn-helix type 11 domain protein; KEGG: sec:SC1699 putative regulatory protein, DeoR family.


ensembl_gene_id: Spro_2644
symbol: Spro_2644
gene_biotype: protein_coding
description:
  KEGG: eca:ECA1960 L-ribulose-5-phosphate 4-epimerase; TIGRFAM: L-ribulose-5-phosphate 4-epimerase; PFAM: class II aldolase/adducin family protein.


ensembl_gene_id: Spro_2646
symbol: Spro_2646
gene_biotype: protein_coding
description:
  PFAM: translation initiation factor SUI1; KEGG: yen:YE1974 translation initiation factor SUI1 family protein.


ensembl_gene_id: Spro_2647
symbol: pyrF
gene_biotype: protein_coding
description:
  Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.


ensembl_gene_id: Spro_2650
symbol: lapB
gene_biotype: protein_coding
description:
  Tetratricopeptide TPR_2 repeat protein; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane; Belongs to the LapB family.


ensembl_gene_id: Spro_2651
symbol: lapA
gene_biotype: protein_coding
description:
  Protein of unknown function DUF1049; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family.


ensembl_gene_id: Spro_2652
symbol: Spro_2652
gene_biotype: protein_coding
description:
  Phosphatidylglycerophosphatase; PFAM: phosphoesterase PA-phosphatase related; KEGG: eca:ECA1944 phosphatidylglycerophosphatase B.


ensembl_gene_id: Spro_2653
symbol: ribA
gene_biotype: protein_coding
description:
  GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.


ensembl_gene_id: Spro_2656
symbol: Spro_2656
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: yen:YE2198 cys regulon transcriptional activator.


ensembl_gene_id: Spro_2657
symbol: topA
gene_biotype: protein_coding
description:
  DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]


ensembl_gene_id: Spro_2660
symbol: Spro_2660
gene_biotype: protein_coding
description:
  PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: ypm:YP_2012 short chain dehydrogenase.


ensembl_gene_id: Spro_2661
symbol: Spro_2661
gene_biotype: protein_coding
description:
  cob(I)alamin adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.


ensembl_gene_id: Spro_2662
symbol: Spro_2662
gene_biotype: protein_coding
description:
  Pseudouridine synthase; PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: ypi:YpsIP31758_1928 ribosomal large subunit pseudouridine synthase B; Belongs to the pseudouridine synthase RsuA family.


ensembl_gene_id: Spro_2665
symbol: Spro_2665
gene_biotype: protein_coding
description:
  TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC domain; KEGG: ypi:YpsIP31758_1929 SUA5/YciO/YrdC/YwlC family protein; Belongs to the SUA5 family.


ensembl_gene_id: Spro_2666
symbol: Spro_2666
gene_biotype: protein_coding
description:
  PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; KEGG: ypi:YpsIP31758_1930 PHP domain protein.


ensembl_gene_id: Spro_2667
symbol: Spro_2667
gene_biotype: protein_coding
description:
  KEGG: eca:ECA2296 anthranilate synthase component I; TIGRFAM: anthranilate synthase component I; PFAM: Anthranilate synthase component I domain protein; Chorismate binding-like.


ensembl_gene_id: Spro_2668
symbol: Spro_2668
gene_biotype: protein_coding
description:
  TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: yen:YE2210 anthranilate synthase component II.


ensembl_gene_id: Spro_2669
symbol: trpD
gene_biotype: protein_coding
description:
  Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).


ensembl_gene_id: Spro_2670
symbol: trpF
gene_biotype: protein_coding
description:
  Indole-3-glycerol-phosphate synthase/phosphoribosylanthranilate isomerase; PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); Indole-3-glycerol phosphate synthase; KEGG: yen:YE2212 tryptophan biosynthesis protein TrpCF.


ensembl_gene_id: Spro_2671
symbol: trpB
gene_biotype: protein_coding
description:
  Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.


ensembl_gene_id: Spro_2672
symbol: trpA
gene_biotype: protein_coding
description:
  Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.


ensembl_gene_id: Spro_2673
symbol: Spro_2673
gene_biotype: protein_coding
description:
  PFAM: transport-associated; SMART: Transport-associated and nodulation region; KEGG: ypi:YpsIP31758_1939 putative phospholipid-binding domain protein.


ensembl_gene_id: Spro_2676
symbol: Spro_2676
gene_biotype: protein_coding
description:
  PFAM: Sulfate transporter/antisigma-factor antagonist STAS; sulphate transporter; KEGG: ypi:YpsIP31758_1943 sulfate permease family protein.


ensembl_gene_id: Spro_2677
symbol: Spro_2677
gene_biotype: protein_coding
description:
  Intracellular septation protein A; Involved in cell division; probably involved in intracellular septation; Belongs to the YciB family.


ensembl_gene_id: Spro_2679
symbol: Spro_2679
gene_biotype: protein_coding
description:
  Transcriptional regulator, LacI family; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: rso:RSc1014 probable transcriptional regulatory DNA-binding repressor transcription regulator protein.


ensembl_gene_id: Spro_2680
symbol: Spro_2680
gene_biotype: protein_coding
description:
  PFAM: Inosine/uridine-preferring nucleoside hydrolase; KEGG: slo:Shew_3859 inosine/uridine-preferring nucleoside hydrolase; Belongs to the IUNH family.


ensembl_gene_id: Spro_2681
symbol: Spro_2681
gene_biotype: protein_coding
description:
  PFAM: major facilitator superfamily MFS_1; KEGG: spc:Sputcn32_1658 major facilitator superfamily MFS_1.


ensembl_gene_id: Spro_2682
symbol: Spro_2682
gene_biotype: protein_coding
description:
  TonB family protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.


ensembl_gene_id: Spro_2683
symbol: queH
gene_biotype: protein_coding
description:
  Protein of unknown function DUF208; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).


ensembl_gene_id: Spro_2687
symbol: Spro_2687
gene_biotype: protein_coding
description:
  PFAM: major facilitator superfamily MFS_1; KEGG: pau:PA14_47640 putative major facilitator superfamily (MFS) transporter.


ensembl_gene_id: Spro_2688
symbol: Spro_2688
gene_biotype: protein_coding
description:
  PFAM: Ferritin Dps family protein; KEGG: vco:VC0395_A2381 DPS family protein; Belongs to the Dps family.


ensembl_gene_id: Spro_2689
symbol: clsA
gene_biotype: protein_coding
description:
  Phospholipase D/Transphosphatidylase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.


ensembl_gene_id: Spro_2690
symbol: Spro_2690
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF440; KEGG: yen:YE2228 hypothetical protein; Belongs to the UPF0263 family.


ensembl_gene_id: Spro_2691
symbol: Spro_2691
gene_biotype: protein_coding
description:
  Transcriptional regulator, DeoR family; PFAM: regulatory protein DeoR; Helix-turn-helix type 11 domain protein; KEGG: bbt:BBta_2220 glycerol-3-phosphate regulon repressor, transcriptional regulator protein, DeoR family.


ensembl_gene_id: Spro_2692
symbol: Spro_2692
gene_biotype: protein_coding
description:
  PFAM: carbohydrate kinase FGGY; KEGG: pae:PA1487 probable carbohydrate kinase; Belongs to the FGGY kinase family.


ensembl_gene_id: Spro_2695
symbol: Spro_2695
gene_biotype: protein_coding
description:
  PFAM: FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: vei:Veis_1679 FAD-dependent pyridine nucleotide-disulphide oxidoreductase.


ensembl_gene_id: Spro_2696
symbol: Spro_2696
gene_biotype: protein_coding
description:
  PFAM: FAD dependent oxidoreductase; BFD domain protein [2Fe-2S]-binding domain protein; KEGG: pfl:PFL_0501 oxidoreductase, FAD-binding.


ensembl_gene_id: Spro_2697
symbol: Spro_2697
gene_biotype: protein_coding
description:
  Oligopeptide/dipeptide ABC transporter, ATPase subunit; KEGG: yen:YE2229 oligopeptide transport ATP-binding protein; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; Belongs to the ABC transporter superfamily.


ensembl_gene_id: Spro_2698
symbol: Spro_2698
gene_biotype: protein_coding
description:
  Oligopeptide/dipeptide ABC transporter, ATPase subunit; KEGG: yen:YE2230 oligopeptide transport ATP-binding protein; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; Belongs to the ABC transporter superfamily.


ensembl_gene_id: Spro_2699
symbol: Spro_2699
gene_biotype: protein_coding
description:
  PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sbo:SBO_1822 OppC.


ensembl_gene_id: Spro_2700
symbol: Spro_2700
gene_biotype: protein_coding
description:
  Alkaline phosphatase; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eca:ECA2323 oligopeptide transport system permease protein.


ensembl_gene_id: Spro_2701
symbol: Spro_2701
gene_biotype: protein_coding
description:
  PFAM: extracellular solute-binding protein family 5; KEGG: yen:YE2233 periplasmic oligopeptide-binding protein precursor.


ensembl_gene_id: Spro_2702
symbol: Spro_2702
gene_biotype: protein_coding
description:
  PFAM: extracellular solute-binding protein family 5; KEGG: yen:YE2234 periplasmic oligopeptide-binding protein precursor.


ensembl_gene_id: Spro_2704
symbol: Spro_2704
gene_biotype: protein_coding
description:
  PFAM: iron-containing alcohol dehydrogenase; aldehyde dehydrogenase; KEGG: yen:YE2238 aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.


ensembl_gene_id: Spro_2706
symbol: Spro_2706
gene_biotype: protein_coding
description:
  PFAM: histone family protein nucleoid-structuring protein H-NS; KEGG: ypi:YpsIP31758_1966 DNA-binding protein H-NS; Belongs to the histone-like protein H-NS family.


ensembl_gene_id: Spro_2707
symbol: Spro_2707
gene_biotype: protein_coding
description:
  PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: kpn:KPN_02492 uridine diphosphate galacturonate 4-epimerase.


ensembl_gene_id: Spro_2708
symbol: Spro_2708
gene_biotype: protein_coding
description:
  PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; KEGG: sgl:SG1368 putative UDP-glucose dehydrogenase.


ensembl_gene_id: Spro_2709
symbol: Spro_2709
gene_biotype: protein_coding
description:
  TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase; KEGG: eca:ECA2329 UTP--glucose-1-phosphate uridylyltransferase.


ensembl_gene_id: Spro_2710
symbol: rssB
gene_biotype: protein_coding
description:
  Response regulator receiver protein; Regulates the turnover of the sigma S factor (RpoS) by promoting its proteolysis in exponentially growing cells. Acts by binding and delivering RpoS to the ClpXP protease. RssB is not co- degraded with RpoS, but is released from the complex and can initiate a new cycle of RpoS recognition and degradation.


ensembl_gene_id: Spro_2712
symbol: Spro_2712
gene_biotype: protein_coding
description:
  PFAM: SEC-C motif domain protein; KEGG: yen:YE2246 hypothetical protein; Belongs to the UPF0225 family.


ensembl_gene_id: Spro_2713
symbol: purU
gene_biotype: protein_coding
description:
  Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).


ensembl_gene_id: Spro_2714
symbol: Spro_2714
gene_biotype: protein_coding
description:
  PFAM: conserved hypothetical protein; KEGG: psa:PST_1098 hypothetical protein; Belongs to the LOG family.


ensembl_gene_id: Spro_2715
symbol: Spro_2715
gene_biotype: protein_coding
description:
  TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase; KEGG: ypi:YpsIP31758_1976 exodeoxyribonuclease III.


ensembl_gene_id: Spro_2716
symbol: Spro_2716
gene_biotype: protein_coding
description:
  PFAM: NUDIX hydrolase; KEGG: yen:YE2255 putative pyrophosphohydrolase; Belongs to the Nudix hydrolase family.


ensembl_gene_id: Spro_2718
symbol: topB
gene_biotype: protein_coding
description:
  DNA topoisomerase III; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA su [...]


ensembl_gene_id: Spro_2719
symbol: selU
gene_biotype: protein_coding
description:
  Rhodanese domain protein; Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2- selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.


ensembl_gene_id: Spro_2722
symbol: Spro_2722
gene_biotype: protein_coding
description:
  KEGG: yen:YE2260 protease IV; TIGRFAM: signal peptide peptidase SppA, 67K type; signal peptide peptidase SppA, 36K type; PFAM: peptidase S49.


ensembl_gene_id: Spro_2724
symbol: Spro_2724
gene_biotype: protein_coding
description:
  Nicotinamidase; PFAM: isochorismatase hydrolase; KEGG: ypi:YpsIP31758_1984 pyrazinamidase/nicotinamidase.


ensembl_gene_id: Spro_2725
symbol: Spro_2725
gene_biotype: protein_coding
description:
  PFAM: glycoside hydrolase family 18; SMART: chitinase II; KEGG: kpn:KPN_01201 putative chitinase II; Belongs to the glycosyl hydrolase 18 family.


ensembl_gene_id: Spro_2727
symbol: msrB
gene_biotype: protein_coding
description:
  TIGRFAM: methionine-R-sulfoxide reductase; PFAM: Methionine sulfoxide reductase B; KEGG: ypi:YpsIP31758_1986 methionine-R-sulfoxide reductase; Belongs to the MsrB Met sulfoxide reductase family.


ensembl_gene_id: Spro_2728
symbol: Spro_2728
gene_biotype: protein_coding
description:
  KEGG: ypi:YpsIP31758_1987 glyceraldehyde-3-phosphate dehydrogenase, type I; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.


ensembl_gene_id: Spro_2729
symbol: Spro_2729
gene_biotype: protein_coding
description:
  PFAM: Aldose 1-epimerase; KEGG: yps:YPTB2082 hypothetical protein; Belongs to the glucose-6-phosphate 1-epimerase family.


ensembl_gene_id: Spro_2732
symbol: Spro_2732
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF444; KEGG: yen:YE2273 hypothetical protein; Belongs to the UPF0229 family.


ensembl_gene_id: Spro_2736
symbol: Spro_2736
gene_biotype: protein_coding
description:
  TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: yen:YE0323 ferrioxamine receptor precursor.


ensembl_gene_id: Spro_2739
symbol: Spro_2739
gene_biotype: protein_coding
description:
  ABC transporter-related protein; PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: eca:ECA1552 ABC transporter ATP-binding protein.


ensembl_gene_id: Spro_2740
symbol: Spro_2740
gene_biotype: protein_coding
description:
  ABC transporter-related protein; PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: eca:ECA1551 ABC transporter ATP binding protein.


ensembl_gene_id: Spro_2741
symbol: Spro_2741
gene_biotype: protein_coding
description:
  PFAM: extracellular solute-binding protein family 5; KEGG: eca:ECA1549 putative ABC transporter substrate-binding protein.


ensembl_gene_id: Spro_2742
symbol: Spro_2742
gene_biotype: protein_coding
description:
  PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eca:ECA1548 putative transport system membrane protein.


ensembl_gene_id: Spro_2744
symbol: Spro_2744
gene_biotype: protein_coding
description:
  TIGRFAM: drug resistance transporter, Bcr/CflA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: ypi:YpsIP31758_1996 drug resistance transporter, Bcr/CflA family.


ensembl_gene_id: Spro_2745
symbol: Spro_2745
gene_biotype: protein_coding
description:
  Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.


ensembl_gene_id: Spro_2746
symbol: dadA
gene_biotype: protein_coding
description:
  D-amino-acid dehydrogenase; Oxidative deamination of D-amino acids; Belongs to the DadA oxidoreductase family.


ensembl_gene_id: Spro_2748
symbol: fadR
gene_biotype: protein_coding
description:
  Fatty acid metabolism transcriptional regulator FadR; Multifunctional regulator of fatty acid metabolism.


ensembl_gene_id: Spro_2749
symbol: nhaB
gene_biotype: protein_coding
description:
  Na+/H+ antiporter NhaB; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.


ensembl_gene_id: Spro_2750
symbol: dsbB
gene_biotype: protein_coding
description:
  Disulphide bond formation protein DsbB; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family.


ensembl_gene_id: Spro_2751
symbol: Spro_2751
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function UPF0153; KEGG: yen:YE2365 hypothetical protein; Belongs to the UPF0260 family.


ensembl_gene_id: Spro_2752
symbol: Spro_2752
gene_biotype: protein_coding
description:
  KEGG: ent:Ent638_1759 protein of unknown function DUF883, ElaB; Belongs to the UPF0337 (CsbD) family.


ensembl_gene_id: Spro_2753
symbol: Spro_2753
gene_biotype: protein_coding
description:
  PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: yen:YE2366 putative fumarylacetoacetate hydrolase family protein.


ensembl_gene_id: Spro_2756
symbol: minC
gene_biotype: protein_coding
description:
  Septum site-determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family.


ensembl_gene_id: Spro_2757
symbol: Spro_2757
gene_biotype: protein_coding
description:
  TIGRFAM: septum site-determining protein MinD; PFAM: Cobyrinic acid ac-diamide synthase; KEGG: eca:ECA2369 septum site-determining protein.


ensembl_gene_id: Spro_2758
symbol: minE
gene_biotype: protein_coding
description:
  Cell division topological specificity factor MinE; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.


ensembl_gene_id: Spro_2759
symbol: rnd
gene_biotype: protein_coding
description:
  Ribonuclease D; Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides; Belongs to the RNase D family.


ensembl_gene_id: Spro_2761
symbol: Spro_2761
gene_biotype: protein_coding
description:
  TIGRFAM: outer membrane lipoprotein, Slp family; PFAM: outer membrane lipoprotein Slp; KEGG: yen:YE2376 putative lipoprotein.


ensembl_gene_id: Spro_2762
symbol: Spro_2762
gene_biotype: protein_coding
description:
  PFAM: peptidase M22 glycoprotease; KEGG: ypi:YpsIP31758_2016 peptidase family M22, nonpeptidase-like protein.


ensembl_gene_id: Spro_2767
symbol: Spro_2767
gene_biotype: protein_coding
description:
  KEGG: yen:YE2382 KHG/KDPG aldolase; TIGRFAM: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; PFAM: KDPG and KHG aldolase.


ensembl_gene_id: Spro_2768
symbol: zwf
gene_biotype: protein_coding
description:
  Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.


ensembl_gene_id: Spro_2769
symbol: Spro_2769
gene_biotype: protein_coding
description:
  Transcriptional regulator, RpiR family; PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); KEGG: yen:YE2384 hex regulon repressor.


ensembl_gene_id: Spro_2770
symbol: Spro_2770
gene_biotype: protein_coding
description:
  KEGG: eca:ECA2481 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family.


ensembl_gene_id: Spro_2771
symbol: lpxM
gene_biotype: protein_coding
description:
  Lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase; Catalyzes the transfer of myristate from myristoyl-acyl carrier protein (ACP) to Kdo(2)-(lauroyl)-lipid IV(A) to form Kdo(2)- lipid A.


ensembl_gene_id: Spro_2772
symbol: Spro_2772
gene_biotype: protein_coding
description:
  Peptidase M23B; PFAM: Peptidoglycan-binding LysM; peptidase M23B; Opacity-associated protein A domain protein; KEGG: ypi:YpsIP31758_2026 peptidase, M23 family.


ensembl_gene_id: Spro_2773
symbol: Spro_2773
gene_biotype: protein_coding
description:
  PFAM: periplasmic solute binding protein; KEGG: yen:YE2388 exported high-affinity zinc uptake system protein.


ensembl_gene_id: Spro_2774
symbol: znuC
gene_biotype: protein_coding
description:
  ABC transporter-related protein; Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family.


ensembl_gene_id: Spro_2775
symbol: Spro_2775
gene_biotype: protein_coding
description:
  ABC-3 protein; PFAM: transport system permease protein; ABC-3 protein; KEGG: ypi:YpsIP31758_2029 high-affinity zinc uptake ABC transporter, permease protein.


ensembl_gene_id: Spro_2776
symbol: ruvB
gene_biotype: protein_coding
description:
  Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.


ensembl_gene_id: Spro_2777
symbol: ruvA
gene_biotype: protein_coding
description:
  Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.


ensembl_gene_id: Spro_2778
symbol: ruvC
gene_biotype: protein_coding
description:
  Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.


ensembl_gene_id: Spro_2781
symbol: aspS
gene_biotype: protein_coding
description:
  aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.


ensembl_gene_id: Spro_2782
symbol: Spro_2782
gene_biotype: protein_coding
description:
  TIGRFAM: putative regulatory protein, FmdB family; PFAM: Putative regulatory protein FmdB; KEGG: aeh:Mlg_0229 putative regulatory protein, FmdB family.


ensembl_gene_id: Spro_2786
symbol: cmoA
gene_biotype: protein_coding
description:
  Putative methyltransferase; Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).


ensembl_gene_id: Spro_2787
symbol: cmoB
gene_biotype: protein_coding
description:
  Putative methyltransferase; Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L- methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5- carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.


ensembl_gene_id: Spro_2792
symbol: murJ
gene_biotype: protein_coding
description:
  Integral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.


ensembl_gene_id: Spro_2794
symbol: Spro_2794
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF480; KEGG: stm:STM1168 putative cytoplasmic protein; Belongs to the UPF0502 family.


ensembl_gene_id: Spro_2795
symbol: Spro_2795
gene_biotype: protein_coding
description:
  PFAM: GCN5-related N-acetyltransferase; KEGG: yen:YE2412 ribosomal-protein-alanine acetyltransferase.


ensembl_gene_id: Spro_2798
symbol: Spro_2798
gene_biotype: protein_coding
description:
  TIGRFAM: glutaredoxin, GrxB family; PFAM: glutaredoxin 2 domain protein; KEGG: ent:Ent638_1578 glutaredoxin, GrxB family.


ensembl_gene_id: Spro_2802
symbol: Spro_2802
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF437; KEGG: yen:YE1787 hypothetical protein; Belongs to the UPF0267 family.


ensembl_gene_id: Spro_2804
symbol: dbpA
gene_biotype: protein_coding
description:
  DEAD/DEAH box helicase domain protein; DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes.


ensembl_gene_id: Spro_2805
symbol: purT
gene_biotype: protein_coding
description:
  Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family.


ensembl_gene_id: Spro_2806
symbol: Spro_2806
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function UPF0181; KEGG: ypi:YpsIP31758_2352 hypothetical protein; Belongs to the UPF0181 family.


ensembl_gene_id: Spro_2808
symbol: Spro_2808
gene_biotype: protein_coding
description:
  TIGRFAM: para-aminobenzoate synthase, subunit I; PFAM: Anthranilate synthase component I domain protein; Chorismate binding-like; KEGG: yps:YPTB1649 para-aminobenzoate synthase component I.


ensembl_gene_id: Spro_2809
symbol: Spro_2809
gene_biotype: protein_coding
description:
  PFAM: NUDIX hydrolase; KEGG: yen:YE1780 MutT-family protein; Belongs to the Nudix hydrolase family. PCD1 subfamily.


ensembl_gene_id: Spro_2810
symbol: Spro_2810
gene_biotype: protein_coding
description:
  KEGG: ypi:YpsIP31758_2355 L-serine ammonia-lyase; TIGRFAM: L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain; Belongs to the iron-sulfur dependent L-serine dehydratase family.


ensembl_gene_id: Spro_2812
symbol: Spro_2812
gene_biotype: protein_coding
description:
  Integral membrane protein TerC; PFAM: CBS domain containing protein; transporter-associated region; Integral membrane protein TerC; KEGG: ypi:YpsIP31758_2367 membrane protein TerC family/CBS domain protein.


ensembl_gene_id: Spro_2813
symbol: Spro_2813
gene_biotype: protein_coding
description:
  KEGG: yps:YPTB1634 PTS system, mannose-specific IIAB component; TIGRFAM: PTS system, mannose/fructose/sorbose family, IIB subunit; PTS system, mannose/fructose/sorbose family, IIA subunit; PFAM: PTS system fructose subfamily IIA component; PTS system sorbose subfamily IIB component.


ensembl_gene_id: Spro_2814
symbol: Spro_2814
gene_biotype: protein_coding
description:
  TIGRFAM: PTS system, mannose/fructose/sorbose family, IIC subunit; PFAM: phosphotransferase system PTS sorbose-specific IIC subunit; KEGG: ypi:YpsIP31758_2369 PTS system, mannose/fructose/sorbose family, IIC component.


ensembl_gene_id: Spro_2815
symbol: Spro_2815
gene_biotype: protein_coding
description:
  TIGRFAM: PTS system, mannose/fructose/sorbose family, IID subunit; PFAM: PTS system mannose/fructose/sorbose family IID component; KEGG: sgl:SG1325 PTS system mannose-specific IID component ManZ.


ensembl_gene_id: Spro_2817
symbol: mntP
gene_biotype: protein_coding
description:
  Protein of unknown function DUF204; Probably functions as a manganese efflux pump. Belongs to the MntP (TC 9.B.29) family.


ensembl_gene_id: Spro_2818
symbol: Spro_2818
gene_biotype: protein_coding
description:
  PFAM: major facilitator superfamily MFS_1; KEGG: vei:Veis_4582 drug resistance transporter, EmrB/QacA subfamily.


ensembl_gene_id: Spro_2820
symbol: Spro_2820
gene_biotype: protein_coding
description:
  rRNA (guanine-N(1)-)-methyltransferase; PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: ypi:YpsIP31758_2376 ribosomal RNA large subunit methyltransferase A.


ensembl_gene_id: Spro_2821
symbol: Spro_2821
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF152; KEGG: ypk:y2562 hypothetical protein; Belongs to the multicopper oxidase YfiH/RL5 family.


ensembl_gene_id: Spro_2822
symbol: Spro_2822
gene_biotype: protein_coding
description:
  PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: yps:YPTB1624 cold shock protein.


ensembl_gene_id: Spro_2823
symbol: Spro_2823
gene_biotype: protein_coding
description:
  PFAM: beta-lactamase domain protein; KEGG: ypi:YpsIP31758_2754 metallo-beta-lactamase family protein.


ensembl_gene_id: Spro_2825
symbol: Spro_2825
gene_biotype: protein_coding
description:
  PFAM: amino acid permease-associated region; KEGG: yen:YE1761 aromatic amino acid transport protein.


ensembl_gene_id: Spro_2833
symbol: Spro_2833
gene_biotype: protein_coding
description:
  Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: yen:YE1753 AraC-family transcriptional regulatory protein.


ensembl_gene_id: Spro_2836
symbol: Spro_2836
gene_biotype: protein_coding
description:
  PFAM: Peptidoglycan-binding LysM; transport-associated; SMART: Transport-associated and nodulation region; KEGG: stm:STM2795 hypothetical protein.


ensembl_gene_id: Spro_2840
symbol: astE
gene_biotype: protein_coding
description:
  Succinylglutamate desuccinylase/aspartoacylase; Transforms N(2)-succinylglutamate into succinate and glutamate; Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.


ensembl_gene_id: Spro_2841
symbol: astB
gene_biotype: protein_coding
description:
  Succinylarginine dihydrolase; Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)- succinylornithine, ammonia and CO(2).


ensembl_gene_id: Spro_2842
symbol: astD
gene_biotype: protein_coding
description:
  Aldehyde dehydrogenase; Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.


ensembl_gene_id: Spro_2843
symbol: astA
gene_biotype: protein_coding
description:
  Arginine N-succinyltransferase; Catalyzes the transfer of succinyl-CoA to arginine to produce N(2)-succinylarginine.


ensembl_gene_id: Spro_2844
symbol: argD
gene_biotype: protein_coding
description:
  Acetylornithine and succinylornithine aminotransferase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.


ensembl_gene_id: Spro_2845
symbol: Spro_2845
gene_biotype: protein_coding
description:
  PFAM: extracellular solute-binding protein family 1; KEGG: vvy:VVA0125 ABC-type sugar transport system, periplasmic component.


ensembl_gene_id: Spro_2846
symbol: Spro_2846
gene_biotype: protein_coding
description:
  PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: vvy:VVA0126 ABC-type sugar transport system, permease component.


ensembl_gene_id: Spro_2847
symbol: Spro_2847
gene_biotype: protein_coding
description:
  PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: vvy:VVA0127 ABC-type sugar transport system, permease component.


ensembl_gene_id: Spro_2848
symbol: Spro_2848
gene_biotype: protein_coding
description:
  PFAM: peptidase M17 leucyl aminopeptidase domain protein; KEGG: gbe:GbCGDNIH1_2202 cytosol aminopeptidase.


ensembl_gene_id: Spro_2849
symbol: Spro_2849
gene_biotype: protein_coding
description:
  ABC transporter-related protein; PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: mmw:Mmwyl1_0607 ABC transporter related; Belongs to the ABC transporter superfamily.


ensembl_gene_id: Spro_2850
symbol: Spro_2850
gene_biotype: protein_coding
description:
  Transcriptional regulator, LacI family; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: smd:Smed_4293 periplasmic binding protein/LacI transcriptional regulator.


ensembl_gene_id: Spro_2853
symbol: Spro_2853
gene_biotype: protein_coding
description:
  Oligopeptide/dipeptide ABC transporter, ATPase subunit; KEGG: kpn:KPN_02023 ATP-binding protein of oligopeptide ABC transport system; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; Belongs to the ABC transporter superfamily.


ensembl_gene_id: Spro_2854
symbol: Spro_2854
gene_biotype: protein_coding
description:
  Oligopeptide/dipeptide ABC transporter, ATPase subunit; KEGG: kpn:KPN_02022 putative ABC transport system ATP-binding protein; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; Belongs to the ABC transporter superfamily.


ensembl_gene_id: Spro_2855
symbol: Spro_2855
gene_biotype: protein_coding
description:
  PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: kpn:KPN_02021 oligopeptide ABC transporter, permease protein.


ensembl_gene_id: Spro_2856
symbol: Spro_2856
gene_biotype: protein_coding
description:
  PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: kpn:KPN_02020 oligopeptide ABC transporter, permease.


ensembl_gene_id: Spro_2857
symbol: Spro_2857
gene_biotype: protein_coding
description:
  PFAM: extracellular solute-binding protein family 5; KEGG: kpn:KPN_02019 putative oligopeptide ABC transporter, oligopeptide-binding protein.


ensembl_gene_id: Spro_2858
symbol: Spro_2858
gene_biotype: protein_coding
description:
  Transcriptional regulator, GntR family with aminotransferase domain; PFAM: regulatory protein GntR HTH; aminotransferase class I and II; KEGG: yen:YE2470 putative GntR-family regulatory protein.


ensembl_gene_id: Spro_2859
symbol: Spro_2859
gene_biotype: protein_coding
description:
  PFAM: cytochrome bd ubiquinol oxidase subunit I; KEGG: yen:YE2471 putative cytochrome oxidase subunit.


ensembl_gene_id: Spro_2860
symbol: Spro_2860
gene_biotype: protein_coding
description:
  TIGRFAM: cytochrome d ubiquinol oxidase, subunit II; PFAM: cytochrome bd ubiquinol oxidase subunit II; KEGG: yen:YE2472 putative cytochrome oxidase subunit.


ensembl_gene_id: Spro_2867
symbol: Spro_2867
gene_biotype: protein_coding
description:
  PFAM: beta-lactamase domain protein; KEGG: ypi:YpsIP31758_2106 metallo-beta-lactamase family protein.


ensembl_gene_id: Spro_2868
symbol: Spro_2868
gene_biotype: protein_coding
description:
  PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: ypi:YpsIP31758_2107 NAD-dependent epimerase/dehydratase family protein.


ensembl_gene_id: Spro_2869
symbol: Spro_2869
gene_biotype: protein_coding
description:
  PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III domain protein; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; KEGG: yps:YPTB1971 putative 3-oxoacyl-(acyl-carrier-protein) synthase III.


ensembl_gene_id: Spro_2879
symbol: Spro_2879
gene_biotype: protein_coding
description:
  Transcriptional regulator, LuxR family; PFAM: regulatory protein LuxR; KEGG: aha:AHA_1023 DNA-binding response regulator, LuxR family.


ensembl_gene_id: Spro_2880
symbol: Spro_2880
gene_biotype: protein_coding
description:
  KEGG: kpn:KPN_02211 nitrate reductase 1, cytochrome b(NR), gamma subunit; TIGRFAM: respiratory nitrate reductase, gamma subunit; PFAM: Nitrate reductase gamma subunit.


ensembl_gene_id: Spro_2881
symbol: Spro_2881
gene_biotype: protein_coding
description:
  TIGRFAM: nitrate reductase molybdenum cofactor assembly chaperone; PFAM: Nitrate reductase delta subunit; KEGG: eca:ECA2033 respiratory nitrate reductase 1 delta chain.


ensembl_gene_id: Spro_2882
symbol: Spro_2882
gene_biotype: protein_coding
description:
  TIGRFAM: nitrate reductase, beta subunit; KEGG: eca:ECA2032 respiratory nitrate reductase 1 beta chain.


ensembl_gene_id: Spro_2883
symbol: Spro_2883
gene_biotype: protein_coding
description:
  TIGRFAM: nitrate reductase, alpha subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; KEGG: eca:ECA2031 respiratory nitrate reductase 1 alpha chain; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: Spro_2886
symbol: Spro_2886
gene_biotype: protein_coding
description:
  PFAM: glycosyl transferase family 2; KEGG: bsu:BG11868 similar to capsular polysaccharide biosynthesis.


ensembl_gene_id: Spro_2887
symbol: Spro_2887
gene_biotype: protein_coding
description:
  PFAM: Carbohydrate-binding CenC domain protein; KEGG: ehi:10.t00010 hypothetical protein Pfam: CBM_4_9.


ensembl_gene_id: Spro_2889
symbol: Spro_2889
gene_biotype: protein_coding
description:
  PFAM: glycosyl transferase group 1; KEGG: gox:GOX0630 lipopolysaccharide core biosynthesis protein WbcM.


ensembl_gene_id: Spro_2892
symbol: Spro_2892
gene_biotype: protein_coding
description:
  PFAM: polysaccharide biosynthesis protein; KEGG: ana:all4430 probable polysaccharide biosynthesis protein.


ensembl_gene_id: Spro_2893
symbol: Spro_2893
gene_biotype: protein_coding
description:
  Non-specific protein-tyrosine kinase; PFAM: lipopolysaccharide biosynthesis protein; KEGG: eca:ECA1419 tyrosine-protein kinase.


ensembl_gene_id: Spro_2896
symbol: Spro_2896
gene_biotype: protein_coding
description:
  PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: tde:TDE1439 epimerase/dehydratase, putative.


ensembl_gene_id: Spro_2897
symbol: Spro_2897
gene_biotype: protein_coding
description:
  Transcriptional regulator, CadC; PFAM: transcriptional regulator domain protein; KEGG: vvy:VVA0492 hypothetical protein.


ensembl_gene_id: Spro_2898
symbol: Spro_2898
gene_biotype: protein_coding
description:
  TIGRFAM: nitrite transporter; PFAM: major facilitator superfamily MFS_1; KEGG: spt:SPA1108 nitrite extrusion protein (nitrite facilitator).


ensembl_gene_id: Spro_2899
symbol: Spro_2899
gene_biotype: protein_coding
description:
  Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase dimerisation and phosphoacceptor region; KEGG: eca:ECA2029 nitrate/nitrite sensor kinase.


ensembl_gene_id: Spro_2900
symbol: Spro_2900
gene_biotype: protein_coding
description:
  Two component transcriptional regulator, LuxR family; PFAM: regulatory protein LuxR; response regulator receiver; Sigma-70 region 4 type 2; KEGG: eca:ECA2028 nitrate/nitrite response regulator.


ensembl_gene_id: Spro_2902
symbol: Spro_2902
gene_biotype: protein_coding
description:
  PFAM: peptidase A24A prepilin type IV; KEGG: yen:YE3574 type 4 prepilin-like proteins leader peptide processing enzyme; Belongs to the peptidase A24 family.


ensembl_gene_id: Spro_2904
symbol: Spro_2904
gene_biotype: protein_coding
description:
  TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: eca:ECA2989 uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family.


ensembl_gene_id: Spro_2905
symbol: Spro_2905
gene_biotype: protein_coding
description:
  PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; BFD domain protein [2Fe-2S]-binding domain protein; KEGG: eca:ECA2990 nitrate reductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.


ensembl_gene_id: Spro_2906
symbol: Spro_2906
gene_biotype: protein_coding
description:
  TIGRFAM: nitrite reductase [NAD(P)H], large subunit; nitrite reductase [NAD(P)H], small subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein; Rieske [2Fe-2S] domain protein; nitrite and sulphite reductase 4Fe-4S region; BFD domain protein [2Fe-2S]-binding domain protein; KEGG: eca:ECA2991 nitrite reductase [NAD(P)H] large subunit.


ensembl_gene_id: Spro_2907
symbol: Spro_2907
gene_biotype: protein_coding
description:
  KEGG: eca:ECA2992 nitrate transport protein; TIGRFAM: nitrate ABC transporter, ATPase subunits C and D; PFAM: ABC transporter related; SMART: AAA ATPase.


ensembl_gene_id: Spro_2908
symbol: Spro_2908
gene_biotype: protein_coding
description:
  TIGRFAM: nitrate ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eca:ECA2993 nitrate transporter permease component.


ensembl_gene_id: Spro_2910
symbol: Spro_2910
gene_biotype: protein_coding
description:
  PFAM: ANTAR domain protein; Nitrate and nitrite sensing domain protein; KEGG: eca:ECA2995 nitrate-and nitrite-responsive positive regulator.


ensembl_gene_id: Spro_2911
symbol: Spro_2911
gene_biotype: protein_coding
description:
  PFAM: extracellular solute-binding protein family 5; KEGG: psp:PSPPH_2742 ABC transporter, periplasmic oligopeptide-binding protein.


ensembl_gene_id: Spro_2912
symbol: Spro_2912
gene_biotype: protein_coding
description:
  ABC transporter-related protein; PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: mmw:Mmwyl1_2060 ABC transporter related.


ensembl_gene_id: Spro_2913
symbol: Spro_2913
gene_biotype: protein_coding
description:
  ABC transporter-related protein; PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: mmw:Mmwyl1_2059 ABC transporter related.


ensembl_gene_id: Spro_2914
symbol: Spro_2914
gene_biotype: protein_coding
description:
  PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: mmw:Mmwyl1_2058 binding-protein-dependent transport systems inner membrane component.


ensembl_gene_id: Spro_2915
symbol: Spro_2915
gene_biotype: protein_coding
description:
  PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: mmw:Mmwyl1_2057 binding-protein-dependent transport systems inner membrane component.


ensembl_gene_id: Spro_2916
symbol: Spro_2916
gene_biotype: protein_coding
description:
  4-phytase; PFAM: extracellular solute-binding protein family 5; KEGG: mmw:Mmwyl1_2056 extracellular solute-binding protein family 5.


ensembl_gene_id: Spro_2917
symbol: Spro_2917
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: yen:YE2474 putative LysR-family transcriptional regulatory protein.


ensembl_gene_id: Spro_2918
symbol: Spro_2918
gene_biotype: protein_coding
description:
  ChaC family protein; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.


ensembl_gene_id: Spro_2919
symbol: Spro_2919
gene_biotype: protein_coding
description:
  PFAM: Siderophore-interacting protein; FAD-binding 9 siderophore-interacting domain protein; KEGG: yen:YE2476 hypothetical protein.


ensembl_gene_id: Spro_2920
symbol: Spro_2920
gene_biotype: protein_coding
description:
  TIGRFAM: calcium/proton exchanger; PFAM: sodium/calcium exchanger membrane region; KEGG: ypi:YpsIP31758_2124 calcium/proton antiporter.


ensembl_gene_id: Spro_2922
symbol: Spro_2922
gene_biotype: protein_coding
description:
  PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; KEGG: dsy:DSY2332 putative anaerobic DMSO reductase chain A precursor; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: Spro_2923
symbol: Spro_2923
gene_biotype: protein_coding
description:
  PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: dsy:DSY2331 putative anaerobic DMSO reductase chain B iron-sulfur subunit.


ensembl_gene_id: Spro_2926
symbol: Spro_2926
gene_biotype: protein_coding
description:
  PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: ent:Ent638_2099 TonB-dependent siderophore receptor.


ensembl_gene_id: Spro_2927
symbol: Spro_2927
gene_biotype: protein_coding
description:
  Dyp-type peroxidase family; Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the tetrapyrrol ring intact. Belongs to the DyP-type peroxidase family.


ensembl_gene_id: Spro_2930
symbol: Spro_2930
gene_biotype: protein_coding
description:
  Sodium/proline symporter; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: Spro_2931
symbol: Spro_2931
gene_biotype: protein_coding
description:
  Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family.  In the N-terminal section; belongs to the proline dehydrogenase family.


ensembl_gene_id: Spro_2934
symbol: Spro_2934
gene_biotype: protein_coding
description:
  ABC transporter-related protein; PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: yen:YE2514 putative amino-acid ABC transporter (ATP-binding protein).


ensembl_gene_id: Spro_2935
symbol: Spro_2935
gene_biotype: protein_coding
description:
  TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ypi:YpsIP31758_2273 amino acid ABC transporter, permease protein.


ensembl_gene_id: Spro_2936
symbol: Spro_2936
gene_biotype: protein_coding
description:
  PFAM: extracellular solute-binding protein family 3; SMART: ionotropic glutamate receptor; KEGG: yen:YE2516 putative cystine-binding periplasmic protein.


ensembl_gene_id: Spro_2937
symbol: dcyD
gene_biotype: protein_coding
description:
  Pyridoxal phosphate-dependent enzyme, D-cysteine desulfhydrase family; Catalyzes the alpha,beta-elimination reaction of D-cysteine and of several D-cysteine derivatives. It could be a defense mechanism against D-cysteine; Belongs to the ACC deaminase/D-cysteine desulfhydrase family.


ensembl_gene_id: Spro_2938
symbol: Spro_2938
gene_biotype: protein_coding
description:
  PFAM: integrase domain protein SAM domain protein; KEGG: yen:YE2518 putative alternative sigma factor regulatory protein.


ensembl_gene_id: Spro_2939
symbol: fliA
gene_biotype: protein_coding
description:
  RNA polymerase, sigma 28 subunit, FliA/WhiG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily.


ensembl_gene_id: Spro_2940
symbol: Spro_2940
gene_biotype: protein_coding
description:
  Flagellin domain protein; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.


ensembl_gene_id: Spro_2941
symbol: Spro_2941
gene_biotype: protein_coding
description:
  Flagellar hook-associated 2 domain protein; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.


ensembl_gene_id: Spro_2943
symbol: fliT
gene_biotype: protein_coding
description:
  Flagellar export chaperone; Dual-function protein that regulates the transcription of class 2 flagellar operons and that also acts as an export chaperone for the filament-capping protein FliD. As a transcriptional regulator, acts as an anti-FlhDC factor; it directly binds FlhC, thus inhibiting the binding of the FlhC/FlhD complex to class 2 promoters, resulting in decreased expression of class 2 flagellar operons. As a chaperone, effects FliD transition to the membrane by preventing its premature polymerization, and by directing it to the export apparatus.


ensembl_gene_id: Spro_2944
symbol: Spro_2944
gene_biotype: protein_coding
description:
  Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: yen:YE2527 putative AraC-family transcriptional regulatory protein.


ensembl_gene_id: Spro_2946
symbol: fliE
gene_biotype: protein_coding
description:
  TIGRFAM: flagellar hook-basal body complex subunit FliE; PFAM: flagellar hook-basal body complex protein FliE; KEGG: eca:ECA1727 flagellar hook-basal body complex protein.


ensembl_gene_id: Spro_2947
symbol: Spro_2947
gene_biotype: protein_coding
description:
  Flagellar M-ring protein FliF; The M ring may be actively involved in energy transduction. Belongs to the FliF family.


ensembl_gene_id: Spro_2948
symbol: Spro_2948
gene_biotype: protein_coding
description:
  Flagellar motor switch protein FliG; FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.


ensembl_gene_id: Spro_2950
symbol: Spro_2950
gene_biotype: protein_coding
description:
  ATPase, FliI/YscN family; KEGG: yps:YPTB1700 flagellum-specific ATP synthase; TIGRFAM: ATPase, FliI/YscN family; flagellar protein export ATPase FliI; PFAM: H+transporting two-sector ATPase alpha/beta subunit central region; SMART: AAA ATPase.


ensembl_gene_id: Spro_2951
symbol: Spro_2951
gene_biotype: protein_coding
description:
  Flagellar export protein FliJ; Flagellar protein that affects chemotactic events. Belongs to the FliJ family.


ensembl_gene_id: Spro_2952
symbol: Spro_2952
gene_biotype: protein_coding
description:
  PFAM: flagellar hook-length control protein; KEGG: ypi:YpsIP31758_2295 flagellar hook-length control protein.


ensembl_gene_id: Spro_2953
symbol: Spro_2953
gene_biotype: protein_coding
description:
  Flagellar basal body-associated protein FliL; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.


ensembl_gene_id: Spro_2954
symbol: Spro_2954
gene_biotype: protein_coding
description:
  Flagellar motor switch protein FliM; FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.


ensembl_gene_id: Spro_2955
symbol: Spro_2955
gene_biotype: protein_coding
description:
  Flagellar motor switch protein FliN; FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliN/MopA/SpaO family.


ensembl_gene_id: Spro_2957
symbol: fliP
gene_biotype: protein_coding
description:
  Flagellar biosynthetic protein FliP; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family.


ensembl_gene_id: Spro_2958
symbol: fliQ
gene_biotype: protein_coding
description:
  Flagellar biosynthetic protein FliQ; Role in flagellar biosynthesis. Belongs to the FliQ/MopD/SpaQ family.


ensembl_gene_id: Spro_2959
symbol: Spro_2959
gene_biotype: protein_coding
description:
  Flagellar biosynthetic protein FliR; Role in flagellar biosynthesis. Belongs to the FliR/MopE/SpaR family.


ensembl_gene_id: Spro_2960
symbol: Spro_2960
gene_biotype: protein_coding
description:
  TIGRFAM: flagellar hook-associated protein 3; PFAM: flagellin domain protein; KEGG: yen:YE2550 flagellar hook-associated protein 3.


ensembl_gene_id: Spro_2961
symbol: flgK
gene_biotype: protein_coding
description:
  TIGRFAM: flagellar hook-associated protein FlgK; PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; KEGG: yen:YE2551 flagellar hook-associated protein 1.


ensembl_gene_id: Spro_2962
symbol: Spro_2962
gene_biotype: protein_coding
description:
  KEGG: yen:YE2552 flagellar protein FlgJ; TIGRFAM: flagellar rod assembly protein/muramidase FlgJ; PFAM: Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase; SMART: Lysozyme subfamily 2.


ensembl_gene_id: Spro_2963
symbol: flgI
gene_biotype: protein_coding
description:
  Flagellar P-ring protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.


ensembl_gene_id: Spro_2964
symbol: flgH
gene_biotype: protein_coding
description:
  Flagellar L-ring protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.


ensembl_gene_id: Spro_2965
symbol: Spro_2965
gene_biotype: protein_coding
description:
  TIGRFAM: flagellar basal-body rod protein FlgG; PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; KEGG: ypi:YpsIP31758_2319 flagellar basal-body rod protein FlgG; Belongs to the flagella basal body rod proteins family.


ensembl_gene_id: Spro_2966
symbol: Spro_2966
gene_biotype: protein_coding
description:
  TIGRFAM: flagellar basal-body rod protein FlgF; PFAM: flagellar basal body rod protein; KEGG: yen:YE2556 flagellar basal-body rod protein FlgF.


ensembl_gene_id: Spro_2967
symbol: Spro_2967
gene_biotype: protein_coding
description:
  PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; flagellar basal body FlaE domain protein; KEGG: yen:YE2557 flagellar hook protein FlgE.


ensembl_gene_id: Spro_2968
symbol: Spro_2968
gene_biotype: protein_coding
description:
  Flagellar hook capping protein; Required for flagellar hook formation. May act as a scaffolding protein.


ensembl_gene_id: Spro_2969
symbol: Spro_2969
gene_biotype: protein_coding
description:
  TIGRFAM: flagellar basal-body rod protein FlgC; PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; KEGG: yen:YE2559 flagellar basal-body rod protein FlgC; Belongs to the flagella basal body rod proteins family.


ensembl_gene_id: Spro_2970
symbol: Spro_2970
gene_biotype: protein_coding
description:
  Flagellar basal-body rod protein FlgB; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.


ensembl_gene_id: Spro_2971
symbol: Spro_2971
gene_biotype: protein_coding
description:
  SAF domain protein; Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P- ring assembly; Belongs to the FlgA family.


ensembl_gene_id: Spro_2972
symbol: Spro_2972
gene_biotype: protein_coding
description:
  PFAM: Anti-sigma-28 factor FlgM family protein; KEGG: eca:ECA1700 negative regulator of flagellin synthesis.


ensembl_gene_id: Spro_2976
symbol: flhA
gene_biotype: protein_coding
description:
  Flagellar biosynthesis protein FlhA; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.


ensembl_gene_id: Spro_2977
symbol: flhB
gene_biotype: protein_coding
description:
  Flagellar biosynthetic protein FlhB; Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the type III secretion exporter family.


ensembl_gene_id: Spro_2978
symbol: Spro_2978
gene_biotype: protein_coding
description:
  Chemotaxis phosphatase, CheZ; Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).


ensembl_gene_id: Spro_2980
symbol: cheB
gene_biotype: protein_coding
description:
  Response regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.


ensembl_gene_id: Spro_2981
symbol: Spro_2981
gene_biotype: protein_coding
description:
  MCP methyltransferase, CheR-type; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.


ensembl_gene_id: Spro_2982
symbol: Spro_2982
gene_biotype: protein_coding
description:
  Methyl-accepting chemotaxis sensory transducer; PFAM: ligand binding Tar domain protein; histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: yen:YE2573 methyl-accepting chemotaxis protein.


ensembl_gene_id: Spro_2983
symbol: Spro_2983
gene_biotype: protein_coding
description:
  Methyl-accepting chemotaxis sensory transducer; PFAM: ligand binding Tar domain protein; histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: yen:YE2575 methyl-accepting chemotaxis protein.


ensembl_gene_id: Spro_2985
symbol: Spro_2985
gene_biotype: protein_coding
description:
  CheA signal transduction histidine kinase; PFAM: CheW domain protein; ATP-binding region ATPase domain protein; Signal transducing histidine kinase homodimeric; Hpt domain protein; CheY binding; KEGG: yen:YE2577 chemotaxis protein CheA.


ensembl_gene_id: Spro_2988
symbol: flhC
gene_biotype: protein_coding
description:
  Flagellar transcriptional activator FlhC; Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhC family.


ensembl_gene_id: Spro_2989
symbol: flhD
gene_biotype: protein_coding
description:
  Flagellar transcriptional activator; Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhD family.


ensembl_gene_id: Spro_2990
symbol: Spro_2990
gene_biotype: protein_coding
description:
  PFAM: Haemolysin expression modulating family protein; KEGG: ecp:ECP_1570 hypothetical protein YdgT.


ensembl_gene_id: Spro_2994
symbol: Spro_2994
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: bra:BRADO6255 putative transcriptional regulatory protein, LysR-family.


ensembl_gene_id: Spro_3000
symbol: Spro_3000
gene_biotype: protein_coding
description:
  PFAM: ImcF domain protein; protein of unknown function DUF1215; KEGG: bbr:BB0816 hypothetical protein.


ensembl_gene_id: Spro_3006
symbol: Spro_3006
gene_biotype: protein_coding
description:
  FHA domain containing protein; PFAM: Forkhead-associated protein; KEGG: azo:azo3884 hypothetical regulatory protein.


ensembl_gene_id: Spro_3007
symbol: Spro_3007
gene_biotype: protein_coding
description:
  PFAM: Protein phosphatase 2C-like; SMART: protein phosphatase 2C domain protein; KEGG: aav:Aave_1469 protein serine/threonine phosphatase.


ensembl_gene_id: Spro_3013
symbol: Spro_3013
gene_biotype: protein_coding
description:
  PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: pmy:Pmen_2331 ATPase AAA-2 domain protein; Belongs to the ClpA/ClpB family.


ensembl_gene_id: Spro_3014
symbol: Spro_3014
gene_biotype: protein_coding
description:
  SMART: tyrosine protein kinase; serine/threonine protein kinase; KEGG: azo:azo3888 putative serine/threonine kinase.


ensembl_gene_id: Spro_3017
symbol: tre1
gene_biotype: protein_coding
description:
  PAAR repeat-containing protein; Toxic component of a contact-dependent interbacterial competition system (also called effector-immunity systems). Acts by ADP-ribosylating a number of target proteins in target cells; E.coli target proteins include FtsZ, EFTu, RNase E, Fis, RL9, SucB, and LolD. FtsZ is thought to be the physiologically relevant target as it is ADP- ribosylated on a critical residue. ADP-ribosylation of FtsZ prevents formation of the FtsZ mid-cell ring and inhibits cell division. Overexpression of the whole Tre1 protein or the ART domain in E.coli is toxic; cells elongate [...]


ensembl_gene_id: Spro_3018
symbol: tri1
gene_biotype: protein_coding
description:
  ADP-ribosyl-(dinitrogen reductase) hydrolase; Immunity component of a contact-dependent interbacterial competition system (also called effector-immunity systems). Acts as an arginine mono-ADP-ribosylhydrolase, mediating the removal of mono-ADP- ribose attached to arginine residues on proteins. De-ADP-ribosylates FtsZ, is able to act on other proteins as well. Neutralizes the toxic activity of cognate toxin Tre1-Sp. Expression of this protein alone in E.coli partially protects the cells against competition by wild-type S.proteamaculans. Neutralizes Tre1-Sp both by occluding its active s [...]


ensembl_gene_id: Spro_3021
symbol: sbmC
gene_biotype: protein_coding
description:
  Transcription activator effector binding; Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell.


ensembl_gene_id: Spro_3022
symbol: kynA
gene_biotype: protein_coding
description:
  Tryptophan 23-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.


ensembl_gene_id: Spro_3024
symbol: Spro_3024
gene_biotype: protein_coding
description:
  PFAM: ornithine cyclodeaminase/mu-crystallin; KEGG: stp:Strop_0460 ornithine cyclodeaminase/mu-crystallin.


ensembl_gene_id: Spro_3025
symbol: mhpE
gene_biotype: protein_coding
description:
  Pyruvate carboxyltransferase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family.


ensembl_gene_id: Spro_3026
symbol: mhpF
gene_biotype: protein_coding
description:
  Semialdehyde dehydrogenase NAD - binding; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.


ensembl_gene_id: Spro_3027
symbol: Spro_3027
gene_biotype: protein_coding
description:
  PFAM: HpcH/HpaI aldolase; KEGG: stp:Strop_0459 HpcH/HpaI aldolase; Belongs to the HpcH/HpaI aldolase family.


ensembl_gene_id: Spro_3030
symbol: Spro_3030
gene_biotype: protein_coding
description:
  PFAM: major facilitator superfamily MFS_1; KEGG: ent:Ent638_2693 major facilitator superfamily MFS_1.


ensembl_gene_id: Spro_3031
symbol: Spro_3031
gene_biotype: protein_coding
description:
  Peptidase M24; PFAM: creatinase; peptidase M24; KEGG: sfr:Sfri_3046 peptidase M24; Belongs to the peptidase M24B family.


ensembl_gene_id: Spro_3032
symbol: norR
gene_biotype: protein_coding
description:
  Transcriptional regulator, NifA subfamily, Fis Family; Required for the expression of anaerobic nitric oxide (NO) reductase, acts as a transcriptional activator for at least the norVW operon. Activation also requires sigma-54.


ensembl_gene_id: Spro_3033
symbol: norV
gene_biotype: protein_coding
description:
  Beta-lactamase domain protein; Anaerobic nitric oxide reductase; uses NADH to detoxify nitric oxide (NO), protecting several 4Fe-4S NO-sensitive enzymes. Has at least 2 reductase partners, only one of which (NorW, flavorubredoxin reductase) has been identified. NO probably binds to the di-iron center; electrons enter from the NorW at rubredoxin and are transferred sequentially to the FMN center and the di-iron center. Also able to function as an aerobic oxygen reductase; In the N-terminal section; belongs to the zinc metallo- hydrolase group 3 family.


ensembl_gene_id: Spro_3034
symbol: norW
gene_biotype: protein_coding
description:
  FAD-dependent pyridine nucleotide-disulphide oxidoreductase; One of at least two accessory proteins for anaerobic nitric oxide (NO) reductase. Reduces the rubredoxin moiety of NO reductase.


ensembl_gene_id: Spro_3035
symbol: Spro_3035
gene_biotype: protein_coding
description:
  TIGRFAM: outer membrane autotransporter barrel domain; PFAM: Pertactin; Autotransporter beta- domain protein; KEGG: psb:Psyr_2034 outer membrane autotransporter barrel.


ensembl_gene_id: Spro_3037
symbol: Spro_3037
gene_biotype: protein_coding
description:
  KEGG: kpn:KPN_01538 acetyl-CoA:acetoacetyl-CoA transferase alpha subunit; TIGRFAM: 3-oxoacid CoA-transferase, A subunit; PFAM: coenzyme A transferase.


ensembl_gene_id: Spro_3038
symbol: Spro_3038
gene_biotype: protein_coding
description:
  KEGG: kpn:KPN_01539 acetyl-CoA:acetoacetyl-CoA transferase beta subunit; TIGRFAM: 3-oxoacid CoA-transferase, B subunit; PFAM: coenzyme A transferase.


ensembl_gene_id: Spro_3039
symbol: Spro_3039
gene_biotype: protein_coding
description:
  TIGRFAM: acetyl-CoA acetyltransferase; beta-ketoadipyl CoA thiolase; PFAM: Thiolase; KEGG: kpn:KPN_01540 acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.


ensembl_gene_id: Spro_3040
symbol: Spro_3040
gene_biotype: protein_coding
description:
  TIGRFAM: 3-oxoadipate enol-lactonase; PFAM: alpha/beta hydrolase fold; KEGG: kpn:KPN_01542 putative 3-oxoadipate enol-lactonase II.


ensembl_gene_id: Spro_3044
symbol: Spro_3044
gene_biotype: protein_coding
description:
  TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; magnesium-translocating P-type ATPase; PFAM: cation transporting ATPase domain protein; Haloacid dehalogenase domain protein hydrolase; E1-E2 ATPase-associated domain protein; KEGG: ypp:YPDSF_1786 Mg(2+) transport ATPase protein B.


ensembl_gene_id: Spro_3047
symbol: Spro_3047
gene_biotype: protein_coding
description:
  PFAM: L-carnitine dehydratase/bile acid-inducible protein F; KEGG: pfo:Pfl_4383 L-carnitine dehydratase/bile acid-inducible protein F; Belongs to the CoA-transferase III family.


ensembl_gene_id: Spro_3048
symbol: Spro_3048
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: bbr:BB1863 putative LysR-family transcriptional regulator.


ensembl_gene_id: Spro_3049
symbol: Spro_3049
gene_biotype: protein_coding
description:
  PFAM: Pyridoxal-dependent decarboxylase; KEGG: sen:SACE_3828 putative amino acid decarboxylase,pyridoxal-dependent protein.


ensembl_gene_id: Spro_3050
symbol: rcsA
gene_biotype: protein_coding
description:
  Transcriptional regulator, LuxR family; Component of the Rcs signaling system, which controls transcription of numerous genes. Binds to DNA to regulate expression of genes.


ensembl_gene_id: Spro_3052
symbol: Spro_3052
gene_biotype: protein_coding
description:
  PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: yen:YE2590 cold shock-like protein CspC2.


ensembl_gene_id: Spro_3053
symbol: Spro_3053
gene_biotype: protein_coding
description:
  PFAM: Ion transport protein; Ion transport 2 domain protein; KEGG: ent:Ent638_2297 ion transport protein.


ensembl_gene_id: Spro_3056
symbol: Spro_3056
gene_biotype: protein_coding
description:
  TIGRFAM: Quinone oxidoreductase putative PIG3; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: ypi:YpsIP31758_1628 putative NAD(P)H quinone oxidoreductase, PIG3 family.


ensembl_gene_id: Spro_3059
symbol: Spro_3059
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: bra:BRADO3708 putative transcriptional regulatory protein, LysR family.


ensembl_gene_id: Spro_3060
symbol: Spro_3060
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF937; KEGG: bte:BTH_I2206 bacterial protein of unknown function (DUF937) family.


ensembl_gene_id: Spro_3062
symbol: Spro_3062
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: bur:Bcep18194_A5815 transcriptional regulator, LysR family.


ensembl_gene_id: Spro_3063
symbol: Spro_3063
gene_biotype: protein_coding
description:
  PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: atc:AGR_L_1000 short chain dehydrogenase.


ensembl_gene_id: Spro_3064
symbol: Spro_3064
gene_biotype: protein_coding
description:
  PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; 3-demethylubiquinone-9 3-methyltransferase; KEGG: bpd:BURPS668_1165 VOC metalloenzyme family protein.


ensembl_gene_id: Spro_3066
symbol: Spro_3066
gene_biotype: protein_coding
description:
  Transposase, IS605 OrfB family; KEGG: ecs:ECs3276 hypothetical protein; TIGRFAM: transposase, IS605 OrfB family; PFAM: putative transposase IS891/IS1136/IS1341 family; transposase IS605 OrfB.


ensembl_gene_id: Spro_3068
symbol: Spro_3068
gene_biotype: protein_coding
description:
  TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: eca:ECA3148 putative regulator.


ensembl_gene_id: Spro_3071
symbol: Spro_3071
gene_biotype: protein_coding
description:
  TIGRFAM: phenylacetic acid degradation protein paaN; PFAM: aldehyde dehydrogenase; MaoC domain protein dehydratase; KEGG: kpn:KPN_01468 phenylacetic acid degradation protein; putative aldehyde dehydrogenase.


ensembl_gene_id: Spro_3072
symbol: Spro_3072
gene_biotype: protein_coding
description:
  TIGRFAM: phenylacetate-CoA oxygenase, PaaG subunit; PFAM: phenylacetic acid catabolic family protein; KEGG: kpn:KPN_01469 phenylacetic acid degradation protein.


ensembl_gene_id: Spro_3073
symbol: Spro_3073
gene_biotype: protein_coding
description:
  TIGRFAM: phenylacetate-CoA oxygenase, PaaH subunit; PFAM: phenylacetic acid degradation B; KEGG: kpn:KPN_01470 phenylacetic acid degradation protein.


ensembl_gene_id: Spro_3074
symbol: Spro_3074
gene_biotype: protein_coding
description:
  TIGRFAM: phenylacetate-CoA oxygenase, PaaI subunit; PFAM: phenylacetic acid catabolic family protein; KEGG: kpn:KPN_01471 phenylacetic acid degradation protein.


ensembl_gene_id: Spro_3075
symbol: Spro_3075
gene_biotype: protein_coding
description:
  TIGRFAM: phenylacetate-CoA oxygenase, PaaJ subunit; PFAM: protein of unknown function DUF59; KEGG: eco:b1391 phenylacetic acid degradation protein.


ensembl_gene_id: Spro_3076
symbol: Spro_3076
gene_biotype: protein_coding
description:
  TIGRFAM: phenylacetate-CoA oxygenase/reductase, PaaK subunit; PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: ecj:JW1387 predicted multicomponent oxygenase/reductase subunit for phenylacetic acid degradation.


ensembl_gene_id: Spro_3077
symbol: Spro_3077
gene_biotype: protein_coding
description:
  PFAM: Enoyl-CoA hydratase/isomerase; KEGG: ecj:JW1388 enoyl-CoA hydratase-isomerase; Belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: Spro_3078
symbol: Spro_3078
gene_biotype: protein_coding
description:
  TIGRFAM: phenylacetate degradation probable enoyl-CoA hydratase paaB; PFAM: Enoyl-CoA hydratase/isomerase; KEGG: kpn:KPN_01475 enoyl-CoA hydratase.


ensembl_gene_id: Spro_3079
symbol: Spro_3079
gene_biotype: protein_coding
description:
  PFAM: 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase NAD-binding; KEGG: kpn:KPN_01476 3-hydroxybutyryl-CoA dehydrogenase.


ensembl_gene_id: Spro_3080
symbol: Spro_3080
gene_biotype: protein_coding
description:
  TIGRFAM: phenylacetic acid degradation protein PaaD; PFAM: thioesterase superfamily protein; KEGG: ecj:JW1391 predicted thioesterase.


ensembl_gene_id: Spro_3081
symbol: Spro_3081
gene_biotype: protein_coding
description:
  KEGG: ecj:JW1392 predicted beta-ketoadipyl CoA thiolase; TIGRFAM: acetyl-CoA acetyltransferase; beta-ketoadipyl CoA thiolase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.


ensembl_gene_id: Spro_3082
symbol: Spro_3082
gene_biotype: protein_coding
description:
  phenylacetate-CoA ligase; Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).


ensembl_gene_id: Spro_3083
symbol: Spro_3083
gene_biotype: protein_coding
description:
  Transcriptional regulator, PaaX family; TIGRFAM: phenylacetic acid degradation operon negative regulatory protein PaaX; PFAM: PaaX domain protein; PaaX domain protein domain; KEGG: ecj:JW1394 DNA-binding transcriptional regulator, aryl-CoA responsive.


ensembl_gene_id: Spro_3084
symbol: Spro_3084
gene_biotype: protein_coding
description:
  TIGRFAM: phenylacetic acid degradation protein PaaY; KEGG: ecj:JW1395 predicted hexapeptide repeat acetyltransferase.


ensembl_gene_id: Spro_3088
symbol: Spro_3088
gene_biotype: protein_coding
description:
  Aspartate transaminase; PFAM: aminotransferase class I and II; KEGG: aha:AHA_0624 aromatic-amino-acid aminotransferase.


ensembl_gene_id: Spro_3091
symbol: Spro_3091
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: mms:mma_2626 transcriptional regulator, LysR family.


ensembl_gene_id: Spro_3093
symbol: Spro_3093
gene_biotype: protein_coding
description:
  PFAM: pyridoxamine 5'-phosphate oxidase-related FMN-binding; KEGG: mms:mma_2628 hypothetical protein.


ensembl_gene_id: Spro_3094
symbol: glgS
gene_biotype: protein_coding
description:
  Glycogen synthesis protein; Major determinant of cell surface composition. Negatively regulates motility, adhesion and synthesis of biofilm exopolysaccharides.


ensembl_gene_id: Spro_3095
symbol: Spro_3095
gene_biotype: protein_coding
description:
  TIGRFAM: succinic semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase; KEGG: acr:Acry_0274 succinic semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: Spro_3096
symbol: Spro_3096
gene_biotype: protein_coding
description:
  PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: rme:Rmet_1778 glyoxalase/bleomycin resistance protein/dioxygenase.


ensembl_gene_id: Spro_3099
symbol: Spro_3099
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: yen:YE3724 putative LysR-family transcriptional regulatory protein.


ensembl_gene_id: Spro_3100
symbol: Spro_3100
gene_biotype: protein_coding
description:
  Quinoprotein glucose dehydrogenase; PFAM: Pyrrolo-quinoline quinone; KEGG: stm:STM0169 glucose dehydrogenase.


ensembl_gene_id: Spro_3102
symbol: Spro_3102
gene_biotype: protein_coding
description:
  TIGRFAM: oligosaccharide/H+ symporter, major facilitator superfamily (MFS); PFAM: proton/sugar symporter LacY; major facilitator superfamily MFS_1; KEGG: eca:ECA1489 lactose permease.


ensembl_gene_id: Spro_3104
symbol: Spro_3104
gene_biotype: protein_coding
description:
  Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein AraC type; AraC protein arabinose-binding/dimerisation; KEGG: cbe:Cbei_4446 transcriptional regulator, AraC family.


ensembl_gene_id: Spro_3106
symbol: Spro_3106
gene_biotype: protein_coding
description:
  TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: stm:STM2013 putative transport protein.


ensembl_gene_id: Spro_3109
symbol: Spro_3109
gene_biotype: protein_coding
description:
  Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein AraC type; ThiJ/PfpI domain protein; KEGG: bxe:Bxe_A0705 transcriptional regulator, AraC family.


ensembl_gene_id: Spro_3110
symbol: mtfA
gene_biotype: protein_coding
description:
  Protein of unknown function DUF980; Involved in the regulation of ptsG expression by binding and inactivating Mlc.


ensembl_gene_id: Spro_3114
symbol: Spro_3114
gene_biotype: protein_coding
description:
  PFAM: periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; KEGG: sme:SMb20366 putative transcriptional regulator protein.


ensembl_gene_id: Spro_3115
symbol: Spro_3115
gene_biotype: protein_coding
description:
  PFAM: extracellular solute-binding protein family 1; KEGG: bov:BOV_A0676 ABC transporter, periplasmic substrate-binding protein.


ensembl_gene_id: Spro_3116
symbol: Spro_3116
gene_biotype: protein_coding
description:
  PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: oan:Oant_3844 binding-protein-dependent transport systems inner membrane component.


ensembl_gene_id: Spro_3119
symbol: Spro_3119
gene_biotype: protein_coding
description:
  KEGG: kpn:KPN_01710 glyceraldehyde-3-phosphate dehydrogenase; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.


ensembl_gene_id: Spro_3120
symbol: Spro_3120
gene_biotype: protein_coding
description:
  Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein AraC type; ThiJ/PfpI domain protein; KEGG: kpn:KPN_01709 putative helix-turn-helix, AraC type.


ensembl_gene_id: Spro_3122
symbol: Spro_3122
gene_biotype: protein_coding
description:
  Transcriptional activator, TenA family; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family.


ensembl_gene_id: Spro_3123
symbol: Spro_3123
gene_biotype: protein_coding
description:
  ABC transporter-related protein; PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: kpn:KPN_01800 putative ABC transporter.


ensembl_gene_id: Spro_3124
symbol: Spro_3124
gene_biotype: protein_coding
description:
  PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: kpn:KPN_01801 binding-protein-dependent transport systems inner membrane component.


ensembl_gene_id: Spro_3125
symbol: Spro_3125
gene_biotype: protein_coding
description:
  PFAM: NLPA lipoprotein; NMT1/THI5 like domain protein; KEGG: hip:CGSHiEE_01225 thiamine biosynthesis protein.


ensembl_gene_id: Spro_3126
symbol: Spro_3126
gene_biotype: protein_coding
description:
  Phosphatidylglycerol--membrane-oligosaccharide glycerophosphotransferase; PFAM: sulfatase; KEGG: ecp:ECP_4690 phosphoglycerol transferase I.


ensembl_gene_id: Spro_3127
symbol: amn
gene_biotype: protein_coding
description:
  AMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.


ensembl_gene_id: Spro_3129
symbol: Spro_3129
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ent:Ent638_2564 transcriptional regulator, LysR family.


ensembl_gene_id: Spro_3131
symbol: Spro_3131
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: psb:Psyr_2945 regulatory protein, LysR:LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Spro_3136
symbol: Spro_3136
gene_biotype: protein_coding
description:
  Glutathione transferase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: pau:PA14_49780 probable fosfomycin resistance protein.


ensembl_gene_id: Spro_3137
symbol: Spro_3137
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: plu:plu2641 hypothetical protein.


ensembl_gene_id: Spro_3139
symbol: Spro_3139
gene_biotype: protein_coding
description:
  PFAM: acriflavin resistance protein; KEGG: ent:Ent638_1874 acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: Spro_3140
symbol: Spro_3140
gene_biotype: protein_coding
description:
  TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: ent:Ent638_1873 efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: Spro_3147
symbol: Spro_3147
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: bbr:BB2390 putative LysR-family transcriptional regulator.


ensembl_gene_id: Spro_3148
symbol: Spro_3148
gene_biotype: protein_coding
description:
  PFAM: NAD(P)H dehydrogenase (quinone); NADPH-dependent FMN reductase; KEGG: bpe:BP2156 hypothetical protein.


ensembl_gene_id: Spro_3152
symbol: Spro_3152
gene_biotype: protein_coding
description:
  Uncharacterized peroxidase-related enzyme; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.


ensembl_gene_id: Spro_3154
symbol: Spro_3154
gene_biotype: protein_coding
description:
  ABC transporter-related protein; PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: eca:ECA0072 ABC transporter ATP-binding protein.


ensembl_gene_id: Spro_3155
symbol: Spro_3155
gene_biotype: protein_coding
description:
  PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eca:ECA0073 ABC transporter permease protein.


ensembl_gene_id: Spro_3156
symbol: Spro_3156
gene_biotype: protein_coding
description:
  PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eca:ECA0074 ABC transporter permease protein.


ensembl_gene_id: Spro_3157
symbol: Spro_3157
gene_biotype: protein_coding
description:
  PFAM: extracellular solute-binding protein family 5; KEGG: kpn:KPN_01854 nickel transport protein (ABC superfamily, peri_bind).


ensembl_gene_id: Spro_3160
symbol: Spro_3160
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: pfl:PFL_1767 transcriptional regulator, LysR family.


ensembl_gene_id: Spro_3162
symbol: Spro_3162
gene_biotype: protein_coding
description:
  TIGRFAM: RarD protein, DMT superfamily transporter; KEGG: pen:PSEEN3058 chloramphenicol-sensitive protein RarD.


ensembl_gene_id: Spro_3163
symbol: Spro_3163
gene_biotype: protein_coding
description:
  PFAM: 4'-phosphopantetheinyl transferase; KEGG: eca:ECA0474 enterobactin synthetase component D (4'-phosphopantetheinyl transferase); Belongs to the P-Pant transferase superfamily.


ensembl_gene_id: Spro_3164
symbol: Spro_3164
gene_biotype: protein_coding
description:
  Glucose-1-phosphatase; PFAM: histidine acid phosphatase; KEGG: ssn:SSON_1012 periplasmic glucose-1-phosphatase.


ensembl_gene_id: Spro_3166
symbol: citG
gene_biotype: protein_coding
description:
  PFAM: triphosphoribosyl-dephospho-CoA protein; KEGG: sec:SC0648 putative modifier of citrate lyase protein.


ensembl_gene_id: Spro_3167
symbol: Spro_3167
gene_biotype: protein_coding
description:
  Holo-ACP synthase; PFAM: Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase; KEGG: yen:YE2649 putative apo-citrate lyase phosphoribosyl-dephospho-CoA transferase.


ensembl_gene_id: Spro_3168
symbol: Spro_3168
gene_biotype: protein_coding
description:
  KEGG: yen:YE2650 citrate lyase alpha chain; TIGRFAM: citrate lyase, alpha subunit; PFAM: Citrate lyase alpha subunit.


ensembl_gene_id: Spro_3169
symbol: Spro_3169
gene_biotype: protein_coding
description:
  KEGG: yen:YE2651 putative citrate lyase beta chain; TIGRFAM: citrate lyase, beta subunit; PFAM: HpcH/HpaI aldolase; Belongs to the HpcH/HpaI aldolase family.


ensembl_gene_id: Spro_3171
symbol: Spro_3171
gene_biotype: protein_coding
description:
  Citrate lyase ligase; Acetylation of prosthetic group (2-(5''-phosphoribosyl)-3'- dephosphocoenzyme-A) of the gamma subunit of citrate lyase.


ensembl_gene_id: Spro_3173
symbol: lacZ
gene_biotype: protein_coding
description:
  PFAM: glycoside hydrolase family 42 domain 5 loop region; glycoside hydrolase family 2 immunoglobulin domain protein beta-sandwich; glycoside hydrolase family 2 TIM barrel; glycoside hydrolase family 2 sugar binding; KEGG: eca:ECA1490 beta-galactosidase; Belongs to the glycosyl hydrolase 2 family.


ensembl_gene_id: Spro_3176
symbol: Spro_3176
gene_biotype: protein_coding
description:
  PFAM: Methionine synthase vitamin-B12 independent; KEGG: ent:Ent638_2113 methionine synthase, vitamin-B12 independent.


ensembl_gene_id: Spro_3178
symbol: Spro_3178
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sbo:SBO_2184 putative transcriptional regulator LysR-type.


ensembl_gene_id: Spro_3179
symbol: Spro_3179
gene_biotype: protein_coding
description:
  TIGRFAM: metabolite/H+ symporter, major facilitator superfamily (MFS); PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: kpn:KPN_02282 putative permease of the major facilitator superfamily.


ensembl_gene_id: Spro_3180
symbol: Spro_3180
gene_biotype: protein_coding
description:
  PFAM: extracellular solute-binding protein family 1; KEGG: kpn:KPN_02281 molybdate transport protein (ABC superfamily, peri_bind).


ensembl_gene_id: Spro_3181
symbol: Spro_3181
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: kpn:KPN_02280 putative transcriptional regulator (LysR family).


ensembl_gene_id: Spro_3182
symbol: Spro_3182
gene_biotype: protein_coding
description:
  PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: ent:Ent638_2281 alcohol dehydrogenase, zinc-binding domain protein.


ensembl_gene_id: Spro_3183
symbol: Spro_3183
gene_biotype: protein_coding
description:
  PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: ent:Ent638_2278 short-chain dehydrogenase/reductase SDR; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: Spro_3187
symbol: Spro_3187
gene_biotype: protein_coding
description:
  Carbamate kinase; KEGG: hip:CGSHiEE_09190 carbamate kinase; TIGRFAM: carbamate kinase; PFAM: aspartate/glutamate/uridylate kinase; Belongs to the carbamate kinase family.


ensembl_gene_id: Spro_3191
symbol: Spro_3191
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: pfl:PFL_2911 transcriptional regulator, LysR family.


ensembl_gene_id: Spro_3192
symbol: katG
gene_biotype: protein_coding
description:
  Catalase/peroxidase HPI; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily.


ensembl_gene_id: Spro_3193
symbol: Spro_3193
gene_biotype: protein_coding
description:
  PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: kpn:KPN_01822 putative transport protein.


ensembl_gene_id: Spro_3194
symbol: sotB
gene_biotype: protein_coding
description:
  Major facilitator superfamily MFS_1; Involved in the efflux of sugars. The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites; Belongs to the major facilitator superfamily. SotB (TC 2.A.1.2) family.


ensembl_gene_id: Spro_3197
symbol: Spro_3197
gene_biotype: protein_coding
description:
  Transcriptional regulator, LacI family; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: mlo:mlr1005 transcriptional regulator.


ensembl_gene_id: Spro_3198
symbol: Spro_3198
gene_biotype: protein_coding
description:
  PFAM: Aspartyl/Asparaginyl beta-hydroxylase; KEGG: bch:Bcen2424_5163 aspartyl/asparaginyl beta-hydroxylase.


ensembl_gene_id: Spro_3199
symbol: Spro_3199
gene_biotype: protein_coding
description:
  ABC transporter-related protein; PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ent:Ent638_2495 ABC transporter related.


ensembl_gene_id: Spro_3200
symbol: Spro_3200
gene_biotype: protein_coding
description:
  ABC transporter-related protein; PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ent:Ent638_2494 ABC transporter related.


ensembl_gene_id: Spro_3201
symbol: Spro_3201
gene_biotype: protein_coding
description:
  PFAM: inner-membrane translocator; KEGG: ent:Ent638_2493 inner-membrane translocator; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: Spro_3202
symbol: Spro_3202
gene_biotype: protein_coding
description:
  PFAM: inner-membrane translocator; KEGG: ent:Ent638_2492 inner-membrane translocator; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: Spro_3203
symbol: Spro_3203
gene_biotype: protein_coding
description:
  PFAM: Extracellular ligand-binding receptor; KEGG: ent:Ent638_2491 extracellular ligand-binding receptor.


ensembl_gene_id: Spro_3205
symbol: Spro_3205
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: pae:PA2921 probable transcriptional regulator.


ensembl_gene_id: Spro_3206
symbol: Spro_3206
gene_biotype: protein_coding
description:
  Amidohydrolase; KEGG: pau:PA14_26260 putative hydrolase; TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein.


ensembl_gene_id: Spro_3207
symbol: Spro_3207
gene_biotype: protein_coding
description:
  PFAM: extracellular solute-binding protein family 3; KEGG: bur:Bcep18194_B2597 ABC amino acid transporter, periplasmic ligand binding protein.


ensembl_gene_id: Spro_3208
symbol: Spro_3208
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF496; KEGG: ypi:YpsIP31758_2417 hypothetical protein; Belongs to the UPF0265 family.


ensembl_gene_id: Spro_3210
symbol: Spro_3210
gene_biotype: protein_coding
description:
  N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD; PFAM: N-acetylmuramoyl-L-alanine amidase family 2; KEGG: ypi:YpsIP31758_1649 N-acetylmuramoyl-L-alanine amidase, family 2.


ensembl_gene_id: Spro_3211
symbol: Spro_3211
gene_biotype: protein_coding
description:
  Putative phage repressor; PFAM: peptidase S24 and S26 domain protein; KEGG: sgl:SG1826 putative transcriptional regulator.


ensembl_gene_id: Spro_3212
symbol: Spro_3212
gene_biotype: protein_coding
description:
  Male sterility domain; PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; Male sterility domain; KEGG: kpn:KPN_03122 hemolysin F.


ensembl_gene_id: Spro_3214
symbol: Spro_3214
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease I; PFAM: Exonuclease RNase T and DNA polymerase III; Exonuclease domain protein; KEGG: ypi:YpsIP31758_2420 exodeoxyribonuclease I.


ensembl_gene_id: Spro_3218
symbol: Spro_3218
gene_biotype: protein_coding
description:
  ABC transporter-related protein; PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: yen:YE2762 putative ABC transport system ATP-binding protein.


ensembl_gene_id: Spro_3219
symbol: Spro_3219
gene_biotype: protein_coding
description:
  Monosaccharide-transporting ATPase; PFAM: inner-membrane translocator; KEGG: yen:YE2763 ribose transport system, permease protein.


ensembl_gene_id: Spro_3221
symbol: Spro_3221
gene_biotype: protein_coding
description:
  PFAM: SMC domain protein; ABC transporter related; SMART: AAA ATPase; KEGG: yen:YE1460 putative siderophore ABC transporter, ATP-binding subunit.


ensembl_gene_id: Spro_3222
symbol: Spro_3222
gene_biotype: protein_coding
description:
  PFAM: transport system permease protein; KEGG: ypi:YpsIP31758_2668 ABC transporter, iron chelate uptake transporter (FeCT) family, permease protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: Spro_3223
symbol: Spro_3223
gene_biotype: protein_coding
description:
  TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: rpa:RPA3076 putative diguanylate cyclase (GGDEF).


ensembl_gene_id: Spro_3224
symbol: Spro_3224
gene_biotype: protein_coding
description:
  PFAM: amino acid permease-associated region; KEGG: ypi:YpsIP31758_2670 lysine-specific permease LysP.


ensembl_gene_id: Spro_3225
symbol: Spro_3225
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: yen:YE1457 putative LysR-family transcriptional regulatory protein.


ensembl_gene_id: Spro_3226
symbol: Spro_3226
gene_biotype: protein_coding
description:
  PFAM: conserved hypothetical protein; KEGG: ypi:YpsIP31758_2674 hypothetical protein; Belongs to the UPF0324 family.


ensembl_gene_id: Spro_3227
symbol: nfo
gene_biotype: protein_coding
description:
  Apurinic endonuclease Apn1; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.


ensembl_gene_id: Spro_3228
symbol: Spro_3228
gene_biotype: protein_coding
description:
  TIGRFAM: PTS system, fructose-specific, IIB subunnit; PTS system, fructose subfamily, IIC subunit; PFAM: phosphotransferase system EIIC; phosphotransferase system PTS fructose-specific IIB subunit; KEGG: yen:YE1449 PTS system, fructose-specific IIBC component.


ensembl_gene_id: Spro_3229
symbol: Spro_3229
gene_biotype: protein_coding
description:
  1-phosphofructokinase; PFAM: PfkB domain protein; KEGG: yen:YE1448 1-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family.


ensembl_gene_id: Spro_3230
symbol: Spro_3230
gene_biotype: protein_coding
description:
  TIGRFAM: phosphocarrier, HPr family; PFAM: phosphocarrier HPr protein; phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; KEGG: yps:YPTB1329 PTS system, fructose-specific II component / phosphocarrier p.


ensembl_gene_id: Spro_3231
symbol: Spro_3231
gene_biotype: protein_coding
description:
  PFAM: NUDIX hydrolase; KEGG: yen:YE1446 putative Mut family protein; Belongs to the Nudix hydrolase family.


ensembl_gene_id: Spro_3232
symbol: Spro_3232
gene_biotype: protein_coding
description:
  PFAM: NapC/NirT cytochrome c domain protein; KEGG: yen:YE1445 cytochrome c-type protein; Belongs to the TorC/TorY family.


ensembl_gene_id: Spro_3233
symbol: Spro_3233
gene_biotype: protein_coding
description:
  KEGG: yen:YE1444 putative molybdopterin-containing oxidoreductase; TIGRFAM: molybdopterin guanine dinucleotide-containing S/N-oxide reductase; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region.


ensembl_gene_id: Spro_3234
symbol: Spro_3234
gene_biotype: protein_coding
description:
  TIGRFAM: sugar efflux transporter; PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA2730 sugar efflux transporter.


ensembl_gene_id: Spro_3236
symbol: Spro_3236
gene_biotype: protein_coding
description:
  TIGRFAM: aromatic amino acid transporter; PFAM: aromatic amino acid permease; KEGG: yen:YE1442 putative tryptophan-specific transport protein.


ensembl_gene_id: Spro_3237
symbol: Spro_3237
gene_biotype: protein_coding
description:
  TIGRFAM: elongation factor P-like protein YeiP; PFAM: Elongation factor P/YeiP protein; Elongation factor KOW domain protein; Elongation factor P; KEGG: ypi:YpsIP31758_2698 elongation factor P-like protein.


ensembl_gene_id: Spro_3238
symbol: uxuA
gene_biotype: protein_coding
description:
  Mannonate dehydratase; Catalyzes the dehydration of D-mannonate; Belongs to the mannonate dehydratase family.


ensembl_gene_id: Spro_3239
symbol: Spro_3239
gene_biotype: protein_coding
description:
  PFAM: Mannitol dehydrogenase domain; Mannitol dehydrogenase rossman domain; KEGG: yen:YE1438 putative D-mannonate oxidoreductase.


ensembl_gene_id: Spro_3241
symbol: Spro_3241
gene_biotype: protein_coding
description:
  PFAM: cobalamin synthesis protein P47K; cobalamin synthesis CobW domain protein; KEGG: ypp:YPDSF_2417 cobalamin synthesis protein.


ensembl_gene_id: Spro_3242
symbol: lpxT
gene_biotype: protein_coding
description:
  Phosphoesterase PA-phosphatase related; Involved in the modification of the lipid A domain of lipopolysaccharides (LPS). Transfers a phosphate group from undecaprenyl pyrophosphate (C55-PP) to lipid A to form lipid A 1- diphosphate. Contributes to the recycling of undecaprenyl phosphate (C55-P); Belongs to the LpxT phosphotransferase family.


ensembl_gene_id: Spro_3246
symbol: Spro_3246
gene_biotype: protein_coding
description:
  PFAM: extracellular solute-binding protein family 5; KEGG: yen:YE1430 putative substrate-binding transport protein.


ensembl_gene_id: Spro_3247
symbol: Spro_3247
gene_biotype: protein_coding
description:
  PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: yen:YE1429 putative ABC transporter integral membrane subunit.


ensembl_gene_id: Spro_3248
symbol: Spro_3248
gene_biotype: protein_coding
description:
  PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ypi:YpsIP31758_2713 ABC transporter, permease protein.


ensembl_gene_id: Spro_3249
symbol: Spro_3249
gene_biotype: protein_coding
description:
  ABC transporter-related protein; PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ypi:YpsIP31758_2714 ABC transporter, ATP-binding protein; Belongs to the ABC transporter superfamily.


ensembl_gene_id: Spro_3251
symbol: Spro_3251
gene_biotype: protein_coding
description:
  TIGRFAM: drug resistance transporter, Bcr/CflA subfamily; PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: ypi:YpsIP31758_2717 bicyclomycin resistance protein.


ensembl_gene_id: Spro_3252
symbol: Spro_3252
gene_biotype: protein_coding
description:
  Pseudouridine synthase; PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: yen:YE1424 ribosomal small subunit pseudouridine synthase A; Belongs to the pseudouridine synthase RsuA family.


ensembl_gene_id: Spro_3253
symbol: Spro_3253
gene_biotype: protein_coding
description:
  PFAM: helicase domain protein; type III restriction protein res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: yen:YE1423 putative DEAD box helicase family protein.


ensembl_gene_id: Spro_3254
symbol: rplY
gene_biotype: protein_coding
description:
  Ribosomal protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family.


ensembl_gene_id: Spro_3256
symbol: Spro_3256
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF1414; KEGG: ypm:YP_0880 hypothetical protein; Belongs to the UPF0352 family.


ensembl_gene_id: Spro_3259
symbol: Spro_3259
gene_biotype: protein_coding
description:
  PFAM: beta-lactamase domain protein; KEGG: sec:SC3660 putative Zn-dependent hydrolase, including glyoxylases.


ensembl_gene_id: Spro_3263
symbol: Spro_3263
gene_biotype: protein_coding
description:
  PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: rpa:RPA2469 putative lactoylglutathione lyase.


ensembl_gene_id: Spro_3264
symbol: Spro_3264
gene_biotype: protein_coding
description:
  PFAM: porin Gram-negative type; KEGG: yen:YE1401 outer membrane protein C, porin; Belongs to the Gram-negative porin family.


ensembl_gene_id: Spro_3266
symbol: rcsD
gene_biotype: protein_coding
description:
  Multi-sensor signal transduction histidine kinase; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB.


ensembl_gene_id: Spro_3267
symbol: rcsB
gene_biotype: protein_coding
description:
  Two component transcriptional regulator, LuxR family; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsB is the response regulator that binds to regulatory DNA regions.


ensembl_gene_id: Spro_3268
symbol: rcsC
gene_biotype: protein_coding
description:
  Integral membrane sensor hybrid histidine kinase; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane- associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB.


ensembl_gene_id: Spro_3269
symbol: gyrA
gene_biotype: protein_coding
description:
  DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.


ensembl_gene_id: Spro_3270
symbol: ubiG
gene_biotype: protein_coding
description:
  Ubiquinone biosynthesis O-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family.


ensembl_gene_id: Spro_3271
symbol: Spro_3271
gene_biotype: protein_coding
description:
  Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.


ensembl_gene_id: Spro_3275
symbol: Spro_3275
gene_biotype: protein_coding
description:
  Competence/damage-inducible protein CinA; TIGRFAM: molybdenum cofactor synthesis domain; competence/damage-inducible protein CinA; PFAM: molybdopterin binding domain; KEGG: yen:YE1383 hypothetical protein.


ensembl_gene_id: Spro_3276
symbol: Spro_3276
gene_biotype: protein_coding
description:
  TIGRFAM: aromatic amino acid transporter; PFAM: aromatic amino acid permease; Amino acid transporter transmembrane; KEGG: ypi:YpsIP31758_2774 tyrosine-specific transport protein.


ensembl_gene_id: Spro_3279
symbol: Spro_3279
gene_biotype: protein_coding
description:
  TIGRFAM: O-succinylbenzoate-CoA ligase; PFAM: AMP-dependent synthetase and ligase; KEGG: yps:YPTB2556 O-succinylbenzoic acid--CoA ligase.


ensembl_gene_id: Spro_3280
symbol: menC
gene_biotype: protein_coding
description:
  Mandelate racemase/muconate lactonizing protein; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB).


ensembl_gene_id: Spro_3281
symbol: menB
gene_biotype: protein_coding
description:
  Naphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA).


ensembl_gene_id: Spro_3282
symbol: menH
gene_biotype: protein_coding
description:
  Alpha/beta hydrolase fold; Catalyzes a proton abstraction reaction that results in 2,5- elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6- hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).


ensembl_gene_id: Spro_3283
symbol: menD
gene_biotype: protein_coding
description:
  2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylic acid synthase/2-oxoglutarate decarboxylase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).


ensembl_gene_id: Spro_3285
symbol: Spro_3285
gene_biotype: protein_coding
description:
  Glycosyltransferase 36; PFAM: putative carbohydrate binding; glycosyltransferase 36; glycosyltransferase 36 associated; KEGG: ent:Ent638_4245 glycosyltransferase 36.


ensembl_gene_id: Spro_3287
symbol: Spro_3287
gene_biotype: protein_coding
description:
  PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: ecv:APECO1_2127 L-idonate 5-dehydrogenase.


ensembl_gene_id: Spro_3288
symbol: Spro_3288
gene_biotype: protein_coding
description:
  PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: ypp:YPDSF_1949 gluconate 5-dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: Spro_3289
symbol: Spro_3289
gene_biotype: protein_coding
description:
  Transcriptional regulator, LacI family; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: yen:YE1364 putative LacI-family transcriptional regulatory protein.


ensembl_gene_id: Spro_3292
symbol: Spro_3292
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF6 transmembrane; KEGG: reu:Reut_A0878 probable transmembrane protein.


ensembl_gene_id: Spro_3294
symbol: Spro_3294
gene_biotype: protein_coding
description:
  PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: stp:Strop_3951 thiamine pyrophosphate enzyme domain protein TPP-binding; Belongs to the TPP enzyme family.


ensembl_gene_id: Spro_3295
symbol: Spro_3295
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: aha:AHA_0743 regulatory protein, LysR:LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Spro_3296
symbol: nuoN
gene_biotype: protein_coding
description:
  Proton-translocating NADH-quinone oxidoreductase, chain N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family.


ensembl_gene_id: Spro_3297
symbol: Spro_3297
gene_biotype: protein_coding
description:
  KEGG: ypi:YpsIP31758_1465 NADH-quinone oxidoreductase, M subunit; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain M; PFAM: NADH/Ubiquinone/plastoquinone (complex I).


ensembl_gene_id: Spro_3298
symbol: Spro_3298
gene_biotype: protein_coding
description:
  KEGG: eca:ECA3018 NADH-quinone oxidoreductase chain L; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain L; PFAM: NADH-Ubiquinone oxidoreductase (complex I) chain 5/L domain protein; NADH/Ubiquinone/plastoquinone (complex I).


ensembl_gene_id: Spro_3299
symbol: nuoK
gene_biotype: protein_coding
description:
  NADH-ubiquinone oxidoreductase chain 4L; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family.


ensembl_gene_id: Spro_3300
symbol: Spro_3300
gene_biotype: protein_coding
description:
  NADH dehydrogenase (quinone); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: Spro_3301
symbol: nuoI
gene_biotype: protein_coding
description:
  NADH-quinone oxidoreductase, chain I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: Spro_3302
symbol: nuoH
gene_biotype: protein_coding
description:
  NADH dehydrogenase (quinone); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.


ensembl_gene_id: Spro_3303
symbol: Spro_3303
gene_biotype: protein_coding
description:
  NADH-quinone oxidoreductase, chain G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family.


ensembl_gene_id: Spro_3304
symbol: Spro_3304
gene_biotype: protein_coding
description:
  NADH-quinone oxidoreductase, F subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family.


ensembl_gene_id: Spro_3305
symbol: Spro_3305
gene_biotype: protein_coding
description:
  TIGRFAM: NADH-quinone oxidoreductase, E subunit; PFAM: NADH dehydrogenase (ubiquinone) 24 kDa subunit; KEGG: ypp:YPDSF_1962 NADH dehydrogenase I chain E.


ensembl_gene_id: Spro_3306
symbol: nuoC
gene_biotype: protein_coding
description:
  NADH dehydrogenase I, D subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family.


ensembl_gene_id: Spro_3307
symbol: nuoB
gene_biotype: protein_coding
description:
  NADH-quinone oxidoreductase, B subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: Spro_3308
symbol: nuoA
gene_biotype: protein_coding
description:
  NADH dehydrogenase (quinone); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family.


ensembl_gene_id: Spro_3309
symbol: Spro_3309
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: yps:YPTB2588 LysR-family transcriptional regulatory protein.


ensembl_gene_id: Spro_3311
symbol: Spro_3311
gene_biotype: protein_coding
description:
  Metal dependent phosphohydrolase; Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates.


ensembl_gene_id: Spro_3312
symbol: Spro_3312
gene_biotype: protein_coding
description:
  PFAM: Citrate transporter; TrkA-C domain protein; TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: yps:YPTB2592 probable sodium:sulfate symporter.


ensembl_gene_id: Spro_3313
symbol: Spro_3313
gene_biotype: protein_coding
description:
  TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: yen:YE1337 putative haloacid dehalogenase-like hydrolase.


ensembl_gene_id: Spro_3316
symbol: ackA
gene_biotype: protein_coding
description:
  Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.


ensembl_gene_id: Spro_3317
symbol: Spro_3317
gene_biotype: protein_coding
description:
  Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.


ensembl_gene_id: Spro_3319
symbol: Spro_3319
gene_biotype: protein_coding
description:
  TIGRFAM: phosphodiesterase, MJ0936 family; PFAM: metallophosphoesterase; KEGG: ypi:YpsIP31758_1434 phosphodiesterase, MJ0936 family.


ensembl_gene_id: Spro_3320
symbol: Spro_3320
gene_biotype: protein_coding
description:
  PFAM: Glutathione S-transferase domain; KEGG: eca:ECA3044 putative glutathione-S transferase; Belongs to the GST superfamily.


ensembl_gene_id: Spro_3322
symbol: Spro_3322
gene_biotype: protein_coding
description:
  Domain of unknown function DUF1731; PFAM: NAD-dependent epimerase/dehydratase; dTDP-4-dehydrorhamnose reductase; domain of unknown function DUF1731; KEGG: ypi:YpsIP31758_1432 NAD dependent epimerase/dehydratase family protein.


ensembl_gene_id: Spro_3323
symbol: Spro_3323
gene_biotype: protein_coding
description:
  ABC transporter-related protein; PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: yen:YE1321 histidine transport ATP-binding protein HisP.


ensembl_gene_id: Spro_3324
symbol: Spro_3324
gene_biotype: protein_coding
description:
  TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: yen:YE1320 histidine transport system permease protein HisM.


ensembl_gene_id: Spro_3325
symbol: Spro_3325
gene_biotype: protein_coding
description:
  TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ypi:YpsIP31758_1429 histidine ABC transporter, permease protein HisQ.


ensembl_gene_id: Spro_3326
symbol: Spro_3326
gene_biotype: protein_coding
description:
  TIGRFAM: cationic amino acid ABC transporter, periplasmic binding protein; PFAM: extracellular solute-binding protein family 3; KEGG: yen:YE1318 histidine-binding periplasmic protein; Belongs to the bacterial solute-binding protein 3 family.


ensembl_gene_id: Spro_3327
symbol: ubiX
gene_biotype: protein_coding
description:
  3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family.


ensembl_gene_id: Spro_3328
symbol: purF
gene_biotype: protein_coding
description:
  Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.


ensembl_gene_id: Spro_3330
symbol: dedD
gene_biotype: protein_coding
description:
  Phosphogluconate dehydratase; Non-essential cell division protein that could be required for efficient cell constriction.


ensembl_gene_id: Spro_3331
symbol: Spro_3331
gene_biotype: protein_coding
description:
  FolC bifunctional protein; Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10- formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.


ensembl_gene_id: Spro_3332
symbol: accD
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.


ensembl_gene_id: Spro_3334
symbol: truA
gene_biotype: protein_coding
description:
  tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.


ensembl_gene_id: Spro_3335
symbol: Spro_3335
gene_biotype: protein_coding
description:
  PFAM: Semialdehyde dehydrogenase NAD - binding; Semialdehyde dehydrogenase dimerisation region; KEGG: ypi:YpsIP31758_1419 aspartate-semialdehyde dehydrogenase family protein; Belongs to the aspartate-semialdehyde dehydrogenase family.


ensembl_gene_id: Spro_3336
symbol: pdxB
gene_biotype: protein_coding
description:
  D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate.


ensembl_gene_id: Spro_3337
symbol: Spro_3337
gene_biotype: protein_coding
description:
  Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: yen:YE1306 putative AraC-family regulatory protein.


ensembl_gene_id: Spro_3339
symbol: Spro_3339
gene_biotype: protein_coding
description:
  Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; Two-component sensor kinase domain protein; KEGG: plu:plu3178 two-component sensor kinase.


ensembl_gene_id: Spro_3340
symbol: Spro_3340
gene_biotype: protein_coding
description:
  Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: plu:plu3179 two-component response regulator.


ensembl_gene_id: Spro_3342
symbol: Spro_3342
gene_biotype: protein_coding
description:
  PFAM: conserved hypothetical protein; KEGG: plu:plu3181 putative tricarboxylic transport membrane protein.


ensembl_gene_id: Spro_3345
symbol: Spro_3345
gene_biotype: protein_coding
description:
  PFAM: transferase hexapeptide repeat containing protein; KEGG: vco:VC0395_0977 antibiotic acetyltransferase.


ensembl_gene_id: Spro_3346
symbol: Spro_3346
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF6 transmembrane; KEGG: yen:YE1304 putative inner membrane protein.


ensembl_gene_id: Spro_3347
symbol: Spro_3347
gene_biotype: protein_coding
description:
  Transcriptional regulator, GntR family with aminotransferase domain; PFAM: regulatory protein GntR HTH; aminotransferase class I and II; KEGG: yen:YE1303 hypothetical protein.


ensembl_gene_id: Spro_3348
symbol: Spro_3348
gene_biotype: protein_coding
description:
  PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; Thioredoxin domain; KEGG: yen:YE1302 putative metal resistance protein.


ensembl_gene_id: Spro_3350
symbol: Spro_3350
gene_biotype: protein_coding
description:
  PFAM: cytochrome c biogenesis protein transmembrane region; KEGG: yen:YE1300 putative metal resistance protein.


ensembl_gene_id: Spro_3352
symbol: Spro_3352
gene_biotype: protein_coding
description:
  Putative flagellar assembly regulatory protein, Flk; Acts as a regulator of flagellar gene expression by modulating the protein level of the anti sigma factor FlgM upon sensing ring completion or hook elongation. Flk could inhibit FlgM secretion by acting as a braking system for the flagellar-associated type III secretion system.


ensembl_gene_id: Spro_3362
symbol: Spro_3362
gene_biotype: protein_coding
description:
  TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein; KEGG: yen:YE3630 putative cation efflux system protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: Spro_3363
symbol: Spro_3363
gene_biotype: protein_coding
description:
  TIGRFAM: efflux transporter, RND family, MFP subunit; KEGG: yen:YE3629 putative efflux system protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: Spro_3368
symbol: Spro_3368
gene_biotype: protein_coding
description:
  PFAM: Beta-ketoacyl synthase; KEGG: yen:YE1287 3-oxoacyl-[acyl-carrier-protein] synthase I; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: Spro_3369
symbol: mnmC
gene_biotype: protein_coding
description:
  Protein of unknown function DUF752; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family.


ensembl_gene_id: Spro_3373
symbol: Spro_3373
gene_biotype: protein_coding
description:
  Peptidase U6 penicillin-insensitive murein endopeptidase; Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus.


ensembl_gene_id: Spro_3374
symbol: aroC
gene_biotype: protein_coding
description:
  Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.


ensembl_gene_id: Spro_3375
symbol: prmB
gene_biotype: protein_coding
description:
  Modification methylase, HemK family; Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue; Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.


ensembl_gene_id: Spro_3377
symbol: Spro_3377
gene_biotype: protein_coding
description:
  TIGRFAM: phosphohistidine phosphatase SixA; PFAM: Phosphoglycerate mutase; KEGG: yen:YE1278 putative phosphohistidine phosphatase.


ensembl_gene_id: Spro_3378
symbol: fadJ
gene_biotype: protein_coding
description:
  Fatty acid oxidation complex, alpha subunit FadJ; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: Spro_3379
symbol: fadI
gene_biotype: protein_coding
description:
  acetyl-CoA C-acyltransferase FadI; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.


ensembl_gene_id: Spro_3381
symbol: Spro_3381
gene_biotype: protein_coding
description:
  PFAM: membrane protein involved in aromatic hydrocarbon degradation; KEGG: kpn:KPN_02726 long-chain fatty acid transport protein (outer membrane flp protein).


ensembl_gene_id: Spro_3385
symbol: Spro_3385
gene_biotype: protein_coding
description:
  TIGRFAM: periplasmic protein thiol--disulphide oxidoreductase DsbE; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: yen:YE1269 thiol:disulfide interchange protein DsbE.


ensembl_gene_id: Spro_3386
symbol: Spro_3386
gene_biotype: protein_coding
description:
  TIGRFAM: cytochrome c-type biogenesis protein CcmF; PFAM: cytochrome c assembly protein; KEGG: yen:YE1268 putative cytochrome c-type biogenesis protein.


ensembl_gene_id: Spro_3387
symbol: ccmE
gene_biotype: protein_coding
description:
  CcmE/CycJ protein; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family.


ensembl_gene_id: Spro_3388
symbol: Spro_3388
gene_biotype: protein_coding
description:
  Heme exporter protein D (CcmD); Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmD/CycX/HelD family.


ensembl_gene_id: Spro_3389
symbol: ccmC
gene_biotype: protein_coding
description:
  Heme exporter protein CcmC; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family.


ensembl_gene_id: Spro_3390
symbol: Spro_3390
gene_biotype: protein_coding
description:
  Heme exporter protein CcmB; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family.


ensembl_gene_id: Spro_3391
symbol: ccmA
gene_biotype: protein_coding
description:
  Heme exporter protein CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.


ensembl_gene_id: Spro_3394
symbol: Spro_3394
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; TIGRFAM: D-serine deaminase transcriptional activator; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ecv:APECO1_4172 D-serine deaminase activator.


ensembl_gene_id: Spro_3399
symbol: Spro_3399
gene_biotype: protein_coding
description:
  TIGRFAM: lytic murein transglycosylase B; KEGG: eca:ECA1083 membrane-bound lytic murein transglycosylase B precursor.


ensembl_gene_id: Spro_3404
symbol: Spro_3404
gene_biotype: protein_coding
description:
  Signal transduction histidine kinase, LytS; PFAM: GAF domain protein; ATP-binding region ATPase domain protein; histidine kinase internal region; 5TM Receptors of the LytS-YhcK type transmembrane region; KEGG: yen:YE1228 two-component system histidine kinase.


ensembl_gene_id: Spro_3405
symbol: Spro_3405
gene_biotype: protein_coding
description:
  PFAM: response regulator receiver; LytTr DNA-binding region; KEGG: yen:YE1227 putative two-component system response-regulator.


ensembl_gene_id: Spro_3407
symbol: glk
gene_biotype: protein_coding
description:
  Glucokinase; KEGG: ecv:APECO1_4149 glucokinase; TIGRFAM: glucokinase; PFAM: Glucokinase; Belongs to the bacterial glucokinase family.


ensembl_gene_id: Spro_3409
symbol: Spro_3409
gene_biotype: protein_coding
description:
  TIGRFAM: aspartate racemase; PFAM: Asp/Glu racemase; KEGG: yen:YE1289 putative aspartate/glutamate racemase.


ensembl_gene_id: Spro_3411
symbol: Spro_3411
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: yen:YE1223 putative LysR-family transcriptional regulatory protein.


ensembl_gene_id: Spro_3412
symbol: Spro_3412
gene_biotype: protein_coding
description:
  PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: yen:YE1222 indole-3-pyruvate decarboxylase.


ensembl_gene_id: Spro_3416
symbol: Spro_3416
gene_biotype: protein_coding
description:
  TIGRFAM: nucleoside transporter; PFAM: Na+ dependent nucleoside transporter; nucleoside recognition domain protein; Na+ dependent nucleoside transporter domain protein; KEGG: yen:YE1217 nucleoside permease.


ensembl_gene_id: Spro_3417
symbol: gltX
gene_biotype: protein_coding
description:
  glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).


ensembl_gene_id: Spro_3418
symbol: Spro_3418
gene_biotype: protein_coding
description:
  PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: ssn:SSON_0547 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase, enterochelin biosynthesis.


ensembl_gene_id: Spro_3419
symbol: Spro_3419
gene_biotype: protein_coding
description:
  PFAM: isochorismatase hydrolase; phosphopantetheine-binding; KEGG: kpn:KPN_00613 2,3-dihydro-2,3-dihydroxybenzoate synthetase, isochroismatase.


ensembl_gene_id: Spro_3420
symbol: Spro_3420
gene_biotype: protein_coding
description:
  TIGRFAM: 2,3-dihydroxybenzoate-AMP ligase; PFAM: AMP-dependent synthetase and ligase; KEGG: kpn:KPN_00612 2,3-dihydroxybenzoate-AMP ligase.


ensembl_gene_id: Spro_3421
symbol: Spro_3421
gene_biotype: protein_coding
description:
  TIGRFAM: isochorismate synthase; PFAM: Chorismate binding-like; KEGG: kpn:KPN_00611 isochorismate synthase.


ensembl_gene_id: Spro_3422
symbol: Spro_3422
gene_biotype: protein_coding
description:
  PFAM: periplasmic binding protein; KEGG: stt:t2274 ferrienterobactin-binding periplasmic protein precursor.


ensembl_gene_id: Spro_3424
symbol: Spro_3424
gene_biotype: protein_coding
description:
  PFAM: transport system permease protein; KEGG: ssn:SSON_0541 ferric enterobactin (enterochelin) transport; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: Spro_3425
symbol: Spro_3425
gene_biotype: protein_coding
description:
  PFAM: transport system permease protein; KEGG: ent:Ent638_1121 transport system permease protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: Spro_3426
symbol: Spro_3426
gene_biotype: protein_coding
description:
  ABC transporter-related protein; PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ecj:JW0580 iron-enterobactin transporter subunit.


ensembl_gene_id: Spro_3427
symbol: Spro_3427
gene_biotype: protein_coding
description:
  TIGRFAM: amino acid adenylation domain; PFAM: AMP-dependent synthetase and ligase; Thioesterase; condensation domain protein; phosphopantetheine-binding; KEGG: ecv:APECO1_1463 enterobactin synthase multienzyme complex component, ATP-dependent.


ensembl_gene_id: Spro_3430
symbol: Spro_3430
gene_biotype: protein_coding
description:
  TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: kpn:KPN_00602 outer membrane porin, receptor for ferric enterobactin and colicins B and D.


ensembl_gene_id: Spro_3431
symbol: Spro_3431
gene_biotype: protein_coding
description:
  PFAM: extracellular solute-binding protein family 5; KEGG: eca:ECA2801 periplasmic dipeptide transport protein.


ensembl_gene_id: Spro_3432
symbol: Spro_3432
gene_biotype: protein_coding
description:
  TIGRFAM: acetolactate synthase, catabolic; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: aha:AHA_1126 acetolactate synthase, catabolic; Belongs to the TPP enzyme family.


ensembl_gene_id: Spro_3434
symbol: Spro_3434
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: cvi:CV_4290 probable transcriptional regulator LysR-family.


ensembl_gene_id: Spro_3435
symbol: Spro_3435
gene_biotype: protein_coding
description:
  PFAM: Ethanolamine ammonia-lyase light chain; KEGG: kpn:KPN_00306 ethanolamine ammonia-lyase small subunit; Belongs to the EutC family.


ensembl_gene_id: Spro_3436
symbol: Spro_3436
gene_biotype: protein_coding
description:
  PFAM: Ethanolamine ammonia lyase large subunit; KEGG: asa:ASA_0956 ethanolamine ammonia-lyase, large subunit.


ensembl_gene_id: Spro_3441
symbol: Spro_3441
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ent:Ent638_2936 transcriptional regulator, LysR family.


ensembl_gene_id: Spro_3444
symbol: ligA
gene_biotype: protein_coding
description:
  DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.


ensembl_gene_id: Spro_3445
symbol: zipA
gene_biotype: protein_coding
description:
  Cell division protein ZipA; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.


ensembl_gene_id: Spro_3446
symbol: cysZ
gene_biotype: protein_coding
description:
  Protein of unknown function DUF540; High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway; Belongs to the CysZ family.


ensembl_gene_id: Spro_3447
symbol: Spro_3447
gene_biotype: protein_coding
description:
  TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: yps:YPTB2714 cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family.


ensembl_gene_id: Spro_3448
symbol: Spro_3448
gene_biotype: protein_coding
description:
  TIGRFAM: phosphocarrier, HPr family; PFAM: phosphocarrier HPr protein; KEGG: eca:ECA0893 PTS system phosphocarrier protein.


ensembl_gene_id: Spro_3449
symbol: Spro_3449
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).


ensembl_gene_id: Spro_3450
symbol: Spro_3450
gene_biotype: protein_coding
description:
  TIGRFAM: PTS system, glucose subfamily, IIA subunit; PFAM: sugar-specific permease EIIA 1 domain; KEGG: yen:YE1205 PTS system, glucose-specific IIA component.


ensembl_gene_id: Spro_3451
symbol: Spro_3451
gene_biotype: protein_coding
description:
  Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: yen:YE1202 putative two-component system sensor kinase.


ensembl_gene_id: Spro_3452
symbol: Spro_3452
gene_biotype: protein_coding
description:
  Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: yen:YE1201 putative two-component system response regulator.


ensembl_gene_id: Spro_3453
symbol: Spro_3453
gene_biotype: protein_coding
description:
  TIGRFAM: cysteine synthase; cysteine synthase B; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: ypi:YpsIP31758_1303 cysteine synthase B; Belongs to the cysteine synthase/cystathionine beta- synthase family.


ensembl_gene_id: Spro_3454
symbol: cysA
gene_biotype: protein_coding
description:
  Sulfate ABC transporter, ATPase subunit; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system.


ensembl_gene_id: Spro_3455
symbol: Spro_3455
gene_biotype: protein_coding
description:
  TIGRFAM: sulfate ABC transporter, inner membrane subunit; sulfate ABC transporter, inner membrane subunit CysW; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: yen:YE1196 sulfate transport system permease protein CysW.


ensembl_gene_id: Spro_3456
symbol: Spro_3456
gene_biotype: protein_coding
description:
  Sulfate ABC transporter, inner membrane subunit; Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: Spro_3457
symbol: Spro_3457
gene_biotype: protein_coding
description:
  TIGRFAM: sulfate ABC transporter, periplasmic sulfate-binding protein; PFAM: extracellular solute-binding protein family 1; KEGG: ypi:YpsIP31758_1299 sulfate/thiosulfate ABC transporter, periplasmic sulfate/thiosulfate-binding protein.


ensembl_gene_id: Spro_3458
symbol: Spro_3458
gene_biotype: protein_coding
description:
  TIGRFAM: Dyp-type peroxidase family; PFAM: Dyp-type peroxidase; KEGG: ypp:YPDSF_2130 hypothetical protein.


ensembl_gene_id: Spro_3462
symbol: Spro_3462
gene_biotype: protein_coding
description:
  PFAM: GCN5-related N-acetyltransferase; KEGG: ent:Ent638_2955 GCN5-related N-acetyltransferase; Belongs to the acetyltransferase family. YpeA subfamily.


ensembl_gene_id: Spro_3463
symbol: Spro_3463
gene_biotype: protein_coding
description:
  N-acetylmuramoyl-L-alanine amidase; PFAM: cell wall hydrolase/autolysin; KEGG: ent:Ent638_2956 N-acetylmuramoyl-L-alanine amidase.


ensembl_gene_id: Spro_3464
symbol: hemF
gene_biotype: protein_coding
description:
  Coproporphyrinogen oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX.


ensembl_gene_id: Spro_3465
symbol: Spro_3465
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF188; KEGG: yen:YE1167 hypothetical protein; Belongs to the UPF0178 family.


ensembl_gene_id: Spro_3466
symbol: Spro_3466
gene_biotype: protein_coding
description:
  PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: sbo:SBO_P082 colicin Js sensitive receptor protein.


ensembl_gene_id: Spro_3467
symbol: Spro_3467
gene_biotype: protein_coding
description:
  Oligopeptidase B; PFAM: peptidase S9 prolyl oligopeptidase active site domain protein; peptidase S9A prolyl oligopeptidase domain protein beta-propeller; KEGG: plu:plu2716 protease II (oligopeptidase B).


ensembl_gene_id: Spro_3468
symbol: Spro_3468
gene_biotype: protein_coding
description:
  TIGRFAM: TonB family protein; KEGG: sbo:SBO_P083 TonB-like colicin Js sensitive putative membrane protein.


ensembl_gene_id: Spro_3470
symbol: Spro_3470
gene_biotype: protein_coding
description:
  PFAM: amino acid permease-associated region; KEGG: eca:ECA2798 probable S-methylmethionine permease.


ensembl_gene_id: Spro_3472
symbol: Spro_3472
gene_biotype: protein_coding
description:
  Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)), Phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase; malic protein domain protein; malic protein NAD-binding; KEGG: yen:YE1162 NADP-dependent malic enzyme.


ensembl_gene_id: Spro_3476
symbol: Spro_3476
gene_biotype: protein_coding
description:
  Chitinase; KEGG: sde:Sde_3870 chitinase; PFAM: glycoside hydrolase family 18; Carbohydrate-binding family V/XII; SMART: chitinase II; Belongs to the glycosyl hydrolase 18 family.


ensembl_gene_id: Spro_3477
symbol: Spro_3477
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: aav:Aave_0757 transcriptional regulator, LysR family.


ensembl_gene_id: Spro_3480
symbol: Spro_3480
gene_biotype: protein_coding
description:
  Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.


ensembl_gene_id: Spro_3481
symbol: Spro_3481
gene_biotype: protein_coding
description:
  PFAM: UreE urease accessory domain protein; KEGG: ypi:YpsIP31758_1080 urease accessory protein UreE.


ensembl_gene_id: Spro_3482
symbol: Spro_3482
gene_biotype: protein_coding
description:
  Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: sgl:SG1549 putative right origin-binding protein.


ensembl_gene_id: Spro_3483
symbol: nudK
gene_biotype: protein_coding
description:
  NUDIX hydrolase; Nucleoside diphosphate sugar hydrolase that hydrolyzes GDP- mannose as its preferred substrate, yielding GMP and mannose-1- phosphate.


ensembl_gene_id: Spro_3484
symbol: Spro_3484
gene_biotype: protein_coding
description:
  TIGRFAM: periplasmic nitrate (or nitrite) reductase c-type cytochrome, NapC/NirT family; PFAM: NapC/NirT cytochrome c domain protein; KEGG: yen:YE1158 cytochrome c-type protein NapC.


ensembl_gene_id: Spro_3485
symbol: Spro_3485
gene_biotype: protein_coding
description:
  Nitrate reductase cytochrome c-type subunit (NapB); Electron transfer subunit of the periplasmic nitrate reductase complex NapAB; Belongs to the NapB family.


ensembl_gene_id: Spro_3486
symbol: napA
gene_biotype: protein_coding
description:
  Periplasmic nitrate reductase, large subunit; Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.


ensembl_gene_id: Spro_3487
symbol: napD
gene_biotype: protein_coding
description:
  NapD family protein; Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin- arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.


ensembl_gene_id: Spro_3488
symbol: napF
gene_biotype: protein_coding
description:
  Ferredoxin-type protein NapF; Could be involved in the maturation of NapA, the catalytic subunit of the periplasmic nitrate reductase, before its export into the periplasm; Belongs to the NapF family.


ensembl_gene_id: Spro_3489
symbol: Spro_3489
gene_biotype: protein_coding
description:
  Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase dimerisation and phosphoacceptor region; KEGG: eca:ECA1900 nitrate/nitrite sensor protein.


ensembl_gene_id: Spro_3490
symbol: Spro_3490
gene_biotype: protein_coding
description:
  Two component transcriptional regulator, LuxR family; PFAM: regulatory protein LuxR; response regulator receiver; Bacterio-opsin activator HTH domain protein; KEGG: yen:YE1153 nitrate/nitrite response regulator protein NarP.


ensembl_gene_id: Spro_3492
symbol: Spro_3492
gene_biotype: protein_coding
description:
  TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: yen:YE1151 multidrug efflux protein.


ensembl_gene_id: Spro_3493
symbol: Spro_3493
gene_biotype: protein_coding
description:
  KEGG: yen:YE1151 multidrug efflux protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: Spro_3494
symbol: Spro_3494
gene_biotype: protein_coding
description:
  PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: ent:Ent638_1099 TonB-dependent receptor.


ensembl_gene_id: Spro_3496
symbol: Spro_3496
gene_biotype: protein_coding
description:
  TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: azo:azo2994 probable TonB-dependent receptor.


ensembl_gene_id: Spro_3500
symbol: Spro_3500
gene_biotype: protein_coding
description:
  PFAM: arsenate reductase and related; KEGG: ypi:YpsIP31758_1256 hypothetical protein; Belongs to the ArsC family.


ensembl_gene_id: Spro_3501
symbol: dapE
gene_biotype: protein_coding
description:
  Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily.


ensembl_gene_id: Spro_3502
symbol: Spro_3502
gene_biotype: protein_coding
description:
  PFAM: peptidase M15B and M15C DD-carboxypeptidase VanY/endolysin; KEGG: ypi:YpsIP31758_1254 D-alanyl-D-alanine carboxypeptidase family protein.


ensembl_gene_id: Spro_3505
symbol: tmcA
gene_biotype: protein_coding
description:
  Protein of unknown function DUF699 ATPase putative; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).


ensembl_gene_id: Spro_3506
symbol: Spro_3506
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function zinc metallopeptidase putative; KEGG: ypi:YpsIP31758_1250 metalloprotease-like protein.


ensembl_gene_id: Spro_3507
symbol: purC
gene_biotype: protein_coding
description:
  KEGG: ypi:YpsIP31758_1249 phosphoribosylaminoimidazole-succinocarboxamide synthase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase.


ensembl_gene_id: Spro_3508
symbol: bamC
gene_biotype: protein_coding
description:
  NlpBDapX family lipoprotein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: Spro_3510
symbol: Spro_3510
gene_biotype: protein_coding
description:
  PFAM: amino acid-binding ACT domain protein; KEGG: ypm:YP_2685 glycine cleavage system regulatory protein.


ensembl_gene_id: Spro_3511
symbol: Spro_3511
gene_biotype: protein_coding
description:
  Peroxiredoxin; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: kpn:KPN_02814 bacterioferritin comigratory protein.


ensembl_gene_id: Spro_3514
symbol: Spro_3514
gene_biotype: protein_coding
description:
  PFAM: regulatory protein AsnC/Lrp family; Helix-turn-helix type 11 domain protein; KEGG: plu:plu4153 hypothetical protein.


ensembl_gene_id: Spro_3515
symbol: Spro_3515
gene_biotype: protein_coding
description:
  PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: swi:Swit_2959 FAD-dependent pyridine nucleotide-disulphide oxidoreductase.


ensembl_gene_id: Spro_3516
symbol: Spro_3516
gene_biotype: protein_coding
description:
  TIGRFAM: putative transcriptional regulator, Rrf2 family; PFAM: protein of unknown function UPF0074; KEGG: swi:Swit_2958 transcriptional regulator, BadM/Rrf2 family.


ensembl_gene_id: Spro_3517
symbol: bepA
gene_biotype: protein_coding
description:
  Peptidase M48 Ste24p; Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.


ensembl_gene_id: Spro_3518
symbol: Spro_3518
gene_biotype: protein_coding
description:
  TIGRFAM: arsenate reductase; PFAM: arsenate reductase and related; KEGG: ypi:YpsIP31758_1238 arsenate reductase (glutaredoxin).


ensembl_gene_id: Spro_3522
symbol: Spro_3522
gene_biotype: protein_coding
description:
  TIGRFAM: uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: ypi:YpsIP31758_1236 uracil permease.


ensembl_gene_id: Spro_3523
symbol: upp
gene_biotype: protein_coding
description:
  Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.


ensembl_gene_id: Spro_3524
symbol: purM
gene_biotype: protein_coding
description:
  Phosphoribosylformylglycinamidine cyclo-ligase; KEGG: yen:YE1127 putative phosphoribosylaminoimidazole synthetase; TIGRFAM: phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein; AIR synthase related protein domain protein.


ensembl_gene_id: Spro_3525
symbol: purN
gene_biotype: protein_coding
description:
  Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.


ensembl_gene_id: Spro_3526
symbol: Spro_3526
gene_biotype: protein_coding
description:
  TIGRFAM: addiction module toxin, RelE/StbE family; PFAM: plasmid stabilization system; KEGG: csa:Csal_0195 plasmid stabilization system.


ensembl_gene_id: Spro_3528
symbol: Spro_3528
gene_biotype: protein_coding
description:
  PFAM: GCN5-related N-acetyltransferase; KEGG: ypi:YpsIP31758_1232 spermidine N(1)-acetyltransferase.


ensembl_gene_id: Spro_3539
symbol: Spro_3539
gene_biotype: protein_coding
description:
  TIGRFAM: phosphate ABC transporter, inner membrane subunit PstA; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: yps:YPTB2800 putative ABC phosphate transporter, permease subunit.


ensembl_gene_id: Spro_3540
symbol: Spro_3540
gene_biotype: protein_coding
description:
  PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ypi:YpsIP31758_1228 phosphate ABC transporter, permease protein PstC.


ensembl_gene_id: Spro_3541
symbol: ppk
gene_biotype: protein_coding
description:
  Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family.


ensembl_gene_id: Spro_3542
symbol: Spro_3542
gene_biotype: protein_coding
description:
  PFAM: Ppx/GppA phosphatase; KEGG: ypi:YpsIP31758_1226 exopolyphosphatase; Belongs to the GppA/Ppx family.


ensembl_gene_id: Spro_3543
symbol: Spro_3543
gene_biotype: protein_coding
description:
  Diguanylate cyclase/phosphodiesterase; PFAM: EAL domain protein; SMART: GGDEF domain containing protein; KEGG: kpn:KPN_02828 putative cytochrome c-type biogenesis protein.


ensembl_gene_id: Spro_3546
symbol: Spro_3546
gene_biotype: protein_coding
description:
  PFAM: MuA-transposase/repressor protein CI DNA-binding; KEGG: ypi:YpsIP31758_3614 hypothetical protein.


ensembl_gene_id: Spro_3547
symbol: Spro_3547
gene_biotype: protein_coding
description:
  PFAM: helix-turn-helix- domain containing protein AraC type; HhH-GPD family protein; Ada metal-binding domain protein; AlkA domain protein; KEGG: reh:H16_B2551 DNA-3-methyladenine glycosylase II, adenosine deaminase.


ensembl_gene_id: Spro_3552
symbol: mdtA
gene_biotype: protein_coding
description:
  TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: yen:YE1109 putitive HlyD family secretion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: Spro_3553
symbol: mdtB
gene_biotype: protein_coding
description:
  PFAM: acriflavin resistance protein; KEGG: ypi:YpsIP31758_1214 multidrug resistance protein MdtB; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtB subfamily.


ensembl_gene_id: Spro_3554
symbol: mdtC
gene_biotype: protein_coding
description:
  PFAM: acriflavin resistance protein; KEGG: yen:YE1107 AcrB/AcrD/AcrF family membrane protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtC subfamily.


ensembl_gene_id: Spro_3556
symbol: Spro_3556
gene_biotype: protein_coding
description:
  Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: yen:YE1105 two-component system, sensor kinase.


ensembl_gene_id: Spro_3557
symbol: Spro_3557
gene_biotype: protein_coding
description:
  Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: yen:YE1104 two-component system response regulator.


ensembl_gene_id: Spro_3558
symbol: vapC
gene_biotype: protein_coding
description:
  PilT protein domain protein; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family.


ensembl_gene_id: Spro_3562
symbol: Spro_3562
gene_biotype: protein_coding
description:
  Diacylglycerol kinase catalytic region; Probably phosphorylates lipids; the in vivo substrate is unknown.


ensembl_gene_id: Spro_3563
symbol: Spro_3563
gene_biotype: protein_coding
description:
  PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: eca:ECA0917 putative starvation sensing mandelate racemase / muconate lactonizing enzyme.


ensembl_gene_id: Spro_3564
symbol: Spro_3564
gene_biotype: protein_coding
description:
  PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: kpn:KPN_03621 putative dehydrogenase, NAD(P)-binding, starvation-sensing protein.


ensembl_gene_id: Spro_3566
symbol: Spro_3566
gene_biotype: protein_coding
description:
  PFAM: Mannitol dehydrogenase domain; Mannitol dehydrogenase rossman domain; KEGG: eca:ECA0920 probable carbohydrate oxidoreductase.


ensembl_gene_id: Spro_3567
symbol: Spro_3567
gene_biotype: protein_coding
description:
  Transcriptional regulator, GntR family; PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: eca:ECA0921 GntR-family transcriptional regulator.


ensembl_gene_id: Spro_3568
symbol: Spro_3568
gene_biotype: protein_coding
description:
  PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; KEGG: plu:plu2781 fructose-biphosphate aldolase class I (FBP aldolase).


ensembl_gene_id: Spro_3569
symbol: Spro_3569
gene_biotype: protein_coding
description:
  TIGRFAM: PTS system, glucitol/sorbitol-specific, IIC subunit; PFAM: PTS system protein II sorbitol-specific factor; KEGG: yen:YE1098 PTS system, glucitol/sorbitol-specific IIC2 component.


ensembl_gene_id: Spro_3570
symbol: Spro_3570
gene_biotype: protein_coding
description:
  KEGG: yen:YE1097 PTS system, glucitol/sorbitol-specific IIBC component; TIGRFAM: PTS system, glucitol/sorbitol-specific, IIBC subunit; PFAM: Sorbitol phosphotransferase protein II domain protein.


ensembl_gene_id: Spro_3571
symbol: Spro_3571
gene_biotype: protein_coding
description:
  PFAM: PTS system glucitol/sorbitol-specific IIA component; KEGG: yen:YE1096 PTS system, glucitol/sorbitol-specific IIA component.


ensembl_gene_id: Spro_3572
symbol: Spro_3572
gene_biotype: protein_coding
description:
  PFAM: short-chain dehydrogenase/reductase SDR; KEGG: yen:YE1095 sorbitol-6-phosphate 2-dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: Spro_3574
symbol: Spro_3574
gene_biotype: protein_coding
description:
  Transcriptional regulator, DeoR family; PFAM: regulatory protein DeoR; Helix-turn-helix type 11 domain protein; KEGG: yen:YE1093 putative glucitol operon repressor.


ensembl_gene_id: Spro_3575
symbol: Spro_3575
gene_biotype: protein_coding
description:
  KpsF/GutQ family protein; KEGG: yen:YE1092 hypothetical protein; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS).


ensembl_gene_id: Spro_3577
symbol: Spro_3577
gene_biotype: protein_coding
description:
  KEGG: eca:ECA3196 phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1.


ensembl_gene_id: Spro_3578
symbol: thiM
gene_biotype: protein_coding
description:
  Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family.


ensembl_gene_id: Spro_3582
symbol: Spro_3582
gene_biotype: protein_coding
description:
  Transcriptional regulator, GntR family; PFAM: regulatory protein GntR HTH; UbiC transcription regulator-associated domain protein; KEGG: ecs:ECs4794 putative transcriptional regulator.


ensembl_gene_id: Spro_3584
symbol: Spro_3584
gene_biotype: protein_coding
description:
  Transcriptional regulator, HxlR family; PFAM: helix-turn-helix HxlR type; KEGG: pfl:PFL_3943 hypothetical protein.


ensembl_gene_id: Spro_3586
symbol: Spro_3586
gene_biotype: protein_coding
description:
  Pseudouridine synthase; PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: ypi:YpsIP31758_2990 RNA pseudouridine synthase family protein; Belongs to the pseudouridine synthase RsuA family.


ensembl_gene_id: Spro_3587
symbol: Spro_3587
gene_biotype: protein_coding
description:
  TIGRFAM: outer membrane autotransporter barrel domain; PFAM: Autotransporter beta- domain protein; KEGG: psp:PSPPH_0790 autotransporter, putative.


ensembl_gene_id: Spro_3589
symbol: Spro_3589
gene_biotype: protein_coding
description:
  Two component transcriptional regulator, LuxR family; PFAM: regulatory protein LuxR; response regulator receiver; Bacterio-opsin activator HTH domain protein; Sigma-70 region 4 type 2; KEGG: reh:H16_B0523 response regulator, NarL-family.


ensembl_gene_id: Spro_3590
symbol: Spro_3590
gene_biotype: protein_coding
description:
  Integral membrane sensor hybrid histidine kinase; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: reh:H16_B0524 signal transduction histidine kinase containing a receiver domain (hybrid).


ensembl_gene_id: Spro_3593
symbol: Spro_3593
gene_biotype: protein_coding
description:
  PFAM: GCN5-related N-acetyltransferase; KEGG: cvi:CV_2338 probable ribosomal-protein-alanine N-acetyltransferase.


ensembl_gene_id: Spro_3596
symbol: guaB
gene_biotype: protein_coding
description:
  Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.


ensembl_gene_id: Spro_3597
symbol: xseA
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease VII, large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family.


ensembl_gene_id: Spro_3598
symbol: Spro_3598
gene_biotype: protein_coding
description:
  Alpha-glucosidase; PFAM: glycoside hydrolase family 31; KEGG: ypi:YpsIP31758_0924 glycosyl hydrolase, family 31 protein; Belongs to the glycosyl hydrolase 31 family.


ensembl_gene_id: Spro_3599
symbol: Spro_3599
gene_biotype: protein_coding
description:
  PFAM: major facilitator superfamily MFS_1; KEGG: ypi:YpsIP31758_0926 putative hexuronate transporter.


ensembl_gene_id: Spro_3600
symbol: Spro_3600
gene_biotype: protein_coding
description:
  Transcriptional regulator, LacI family; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: ypi:YpsIP31758_0927 sugar-binding transcriptional regulator, LacI family.


ensembl_gene_id: Spro_3605
symbol: der
gene_biotype: protein_coding
description:
  Small GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.


ensembl_gene_id: Spro_3606
symbol: bamB
gene_biotype: protein_coding
description:
  Pyrrolo-quinoline quinone; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: Spro_3608
symbol: hisS
gene_biotype: protein_coding
description:
  KEGG: yen:YE1074 histidyl-tRNA synthetase; TIGRFAM: histidyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); Anticodon-binding domain protein.


ensembl_gene_id: Spro_3609
symbol: ispG
gene_biotype: protein_coding
description:
  1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family.


ensembl_gene_id: Spro_3610
symbol: rodZ
gene_biotype: protein_coding
description:
  Transcriptional regulator, XRE family; Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis.


ensembl_gene_id: Spro_3611
symbol: Spro_3611
gene_biotype: protein_coding
description:
  KEGG: yen:YE1071 putative fimbrial biogenesis protein; TIGRFAM: type IV pilus biogenesis/stability protein PilW; PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein.


ensembl_gene_id: Spro_3612
symbol: rlmN
gene_biotype: protein_coding
description:
  Radical SAM enzyme, Cfr family; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family.


ensembl_gene_id: Spro_3613
symbol: ndk
gene_biotype: protein_coding
description:
  Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.


ensembl_gene_id: Spro_3614
symbol: Spro_3614
gene_biotype: protein_coding
description:
  TIGRFAM: penicillin-binding protein 1C; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; Penicillin-binding domain protein; KEGG: yen:YE1067 penicillin-binding protein.


ensembl_gene_id: Spro_3616
symbol: Spro_3616
gene_biotype: protein_coding
description:
  Transcriptional regulator, LacI family; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: ypi:YpsIP31758_1855 sugar-binding transcriptional regulator, LacI family.


ensembl_gene_id: Spro_3618
symbol: Spro_3618
gene_biotype: protein_coding
description:
  PFAM: aminotransferase class I and II; KEGG: ypi:YpsIP31758_1857 aminotransferase, classes I and II.


ensembl_gene_id: Spro_3622
symbol: Spro_3622
gene_biotype: protein_coding
description:
  TIGRFAM: ferredoxin, 2Fe-2S type, ISC system; PFAM: ferredoxin; KEGG: plu:plu3278 ferredoxin, 2Fe-2S.


ensembl_gene_id: Spro_3623
symbol: hscA
gene_biotype: protein_coding
description:
  Fe-S protein assembly chaperone HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. Involved in the maturation of IscU.


ensembl_gene_id: Spro_3624
symbol: hscB
gene_biotype: protein_coding
description:
  Co-chaperone Hsc20; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family.


ensembl_gene_id: Spro_3625
symbol: iscA
gene_biotype: protein_coding
description:
  Iron-sulfur cluster assembly protein IscA; Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system TrxA/TrxB.


ensembl_gene_id: Spro_3626
symbol: Spro_3626
gene_biotype: protein_coding
description:
  FeS cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.


ensembl_gene_id: Spro_3627
symbol: iscS
gene_biotype: protein_coding
description:
  Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.


ensembl_gene_id: Spro_3628
symbol: iscR
gene_biotype: protein_coding
description:
  Transcriptional regulator, BadM/Rrf2 family; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.


ensembl_gene_id: Spro_3631
symbol: Spro_3631
gene_biotype: protein_coding
description:
  PFAM: high-affinity nickel-transporter; KEGG: yen:YE1052 hypothetical protein; Belongs to the NiCoT transporter (TC 2.A.52) family.


ensembl_gene_id: Spro_3633
symbol: Spro_3633
gene_biotype: protein_coding
description:
  Transcriptional antiterminator, BglG; PFAM: PRD domain protein; KEGG: ypa:YPA_2343 putative RNA-binding protein.


ensembl_gene_id: Spro_3634
symbol: Spro_3634
gene_biotype: protein_coding
description:
  Chloramphenicol O-acetyltransferase; PFAM: proton/sugar symporter LacY; major facilitator superfamily MFS_1; KEGG: yen:YE1049 putative transport permease protein.


ensembl_gene_id: Spro_3635
symbol: Spro_3635
gene_biotype: protein_coding
description:
  Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.


ensembl_gene_id: Spro_3637
symbol: Spro_3637
gene_biotype: protein_coding
description:
  PFAM: Na+ dependent nucleoside transporter; nucleoside recognition domain protein; Na+ dependent nucleoside transporter domain protein; KEGG: ent:Ent638_2927 nucleoside transporter.


ensembl_gene_id: Spro_3638
symbol: glyA
gene_biotype: protein_coding
description:
  Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.


ensembl_gene_id: Spro_3639
symbol: hmp
gene_biotype: protein_coding
description:
  Oxidoreductase FAD/NAD(P)-binding domain protein; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress; Belongs to the globin family. Two-domain flavohemoproteins subfamily.


ensembl_gene_id: Spro_3640
symbol: Spro_3640
gene_biotype: protein_coding
description:
  Gluconate 2-dehydrogenase (acceptor); PFAM: cytochrome c class I; KEGG: asa:ASA_2963 cytochrome c, class I.


ensembl_gene_id: Spro_3642
symbol: patD
gene_biotype: protein_coding
description:
  Aldehyde dehydrogenase; Catalyzes the oxidation 4-aminobutanal (gamma- aminobutyraldehyde) to 4-aminobutanoate (gamma-aminobutyrate or GABA). This is the second step in one of two pathways for putrescine degradation, where putrescine is converted into 4-aminobutanoate via 4- aminobutanal. Also functions as a 5-aminopentanal dehydrogenase in a a L-lysine degradation pathway to succinate that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate.


ensembl_gene_id: Spro_3643
symbol: Spro_3643
gene_biotype: protein_coding
description:
  PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: pfo:Pfl_1045 binding-protein-dependent transport systems inner membrane component.


ensembl_gene_id: Spro_3644
symbol: Spro_3644
gene_biotype: protein_coding
description:
  PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: pen:PSEEN1240 ABC transporter, permease protein.


ensembl_gene_id: Spro_3645
symbol: Spro_3645
gene_biotype: protein_coding
description:
  KEGG: pfo:Pfl_1047 spermidine/putrescine ABC transporter ATP-binding subunit; TIGRFAM: spermidine/putrescine ABC transporter ATPase subunit; PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; Belongs to the ABC transporter superfamily.


ensembl_gene_id: Spro_3646
symbol: Spro_3646
gene_biotype: protein_coding
description:
  PFAM: extracellular solute-binding protein family 1; KEGG: ssn:SSON_1697 putative transport protein.


ensembl_gene_id: Spro_3647
symbol: Spro_3647
gene_biotype: protein_coding
description:
  PFAM: aldehyde dehydrogenase; KEGG: pfo:Pfl_1049 betaine-aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: Spro_3648
symbol: Spro_3648
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: pfo:Pfl_1050 transcriptional regulator, LysR family.


ensembl_gene_id: Spro_3649
symbol: Spro_3649
gene_biotype: protein_coding
description:
  PFAM: nitrogen regulatory protein P-II; KEGG: plu:plu3309 nitrogen regulatory protein P-II.1; Belongs to the P(II) protein family.


ensembl_gene_id: Spro_3650
symbol: nadE
gene_biotype: protein_coding
description:
  NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.


ensembl_gene_id: Spro_3651
symbol: Spro_3651
gene_biotype: protein_coding
description:
  Two component, sigma54 specific, transcriptional regulator, Fis family; PFAM: response regulator receiver; sigma-54 factor interaction domain-containing protein; SMART: AAA ATPase; KEGG: yen:YE1037 two-component system response regulator.


ensembl_gene_id: Spro_3653
symbol: Spro_3653
gene_biotype: protein_coding
description:
  Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: ypi:YpsIP31758_1150 putative sensor-like histidine kinase YfhK.


ensembl_gene_id: Spro_3654
symbol: purL
gene_biotype: protein_coding
description:
  Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.


ensembl_gene_id: Spro_3655
symbol: mltF
gene_biotype: protein_coding
description:
  Lytic transglycosylase catalytic; Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella. In the N-terminal section; belongs to the bacterial solute- binding protein 3 family.


ensembl_gene_id: Spro_3656
symbol: tadA
gene_biotype: protein_coding
description:
  CMP/dCMP deaminase zinc-binding; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.


ensembl_gene_id: Spro_3658
symbol: Spro_3658
gene_biotype: protein_coding
description:
  PFAM: iron-containing alcohol dehydrogenase; KEGG: ent:Ent638_0142 iron-containing alcohol dehydrogenase.


ensembl_gene_id: Spro_3659
symbol: Spro_3659
gene_biotype: protein_coding
description:
  TIGRFAM: HAD superfamily (subfamily IF) hydrolase, YfhB; KEGG: ypi:YpsIP31758_1144 HAD hydrolase YfhB.


ensembl_gene_id: Spro_3660
symbol: Spro_3660
gene_biotype: protein_coding
description:
  PFAM: phosphotransferase system PTS EIIB protein; phosphotransferase system EIIC; KEGG: ent:Ent638_3046 phosphotransferase system, EIIC.


ensembl_gene_id: Spro_3661
symbol: murQ
gene_biotype: protein_coding
description:
  Glucokinase regulatory-like protein; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.


ensembl_gene_id: Spro_3662
symbol: Spro_3662
gene_biotype: protein_coding
description:
  Transcriptional regulator, RpiR family; PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); KEGG: yen:YE1025 putative RpiR-family transcriptional regulatory protein.


ensembl_gene_id: Spro_3664
symbol: Spro_3664
gene_biotype: protein_coding
description:
  PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: ecv:APECO1_3969 putative 4Fe-4S cluster-containing protein.


ensembl_gene_id: Spro_3665
symbol: acpS
gene_biotype: protein_coding
description:
  Holo-acyl-carrier-protein synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.


ensembl_gene_id: Spro_3666
symbol: pdxJ
gene_biotype: protein_coding
description:
  Pyridoxal phosphate biosynthetic protein PdxJ; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.


ensembl_gene_id: Spro_3668
symbol: era
gene_biotype: protein_coding
description:
  GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.


ensembl_gene_id: Spro_3669
symbol: rnc
gene_biotype: protein_coding
description:
  Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.


ensembl_gene_id: Spro_3670
symbol: Spro_3670
gene_biotype: protein_coding
description:
  KEGG: yen:YE1016 signal peptidase I; TIGRFAM: signal peptidase I; PFAM: peptidase S24 and S26 domain protein; Belongs to the peptidase S26 family.


ensembl_gene_id: Spro_3671
symbol: lepA
gene_biotype: protein_coding
description:
  GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.


ensembl_gene_id: Spro_3673
symbol: Spro_3673
gene_biotype: protein_coding
description:
  PFAM: Positive regulator of sigma(E) RseC/MucC; KEGG: ypi:YpsIP31758_1132 sigma-E factor regulatory protein RseC.


ensembl_gene_id: Spro_3675
symbol: Spro_3675
gene_biotype: protein_coding
description:
  Anti sigma-E protein, RseA; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish  [...]


ensembl_gene_id: Spro_3676
symbol: Spro_3676
gene_biotype: protein_coding
description:
  RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-70; RNA polymerase sigma-70 RpoE type; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: ypi:YpsIP31758_1129 RNA polymerase sigma factor RpoE; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: Spro_3678
symbol: Spro_3678
gene_biotype: protein_coding
description:
  Methyltransferase small; Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).


ensembl_gene_id: Spro_3679
symbol: srmB
gene_biotype: protein_coding
description:
  DEAD/DEAH box helicase domain protein; DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity; Belongs to the DEAD box helicase family. SrmB subfamily.


ensembl_gene_id: Spro_3682
symbol: grcA
gene_biotype: protein_coding
description:
  Formate C-acetyltransferase glycine radical; Acts as a radical domain for damaged PFL and possibly other radical proteins.


ensembl_gene_id: Spro_3683
symbol: ung
gene_biotype: protein_coding
description:
  uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.


ensembl_gene_id: Spro_3684
symbol: grpE
gene_biotype: protein_coding
description:
  GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]


ensembl_gene_id: Spro_3685
symbol: nadK
gene_biotype: protein_coding
description:
  ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.


ensembl_gene_id: Spro_3687
symbol: bamE
gene_biotype: protein_coding
description:
  SmpA/OmlA domain protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: Spro_3688
symbol: rnfH
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function UPF0125; KEGG: ypi:YpsIP31758_2891 hypothetical protein; Belongs to the UPF0125 (RnfH) family.


ensembl_gene_id: Spro_3690
symbol: smpB
gene_biotype: protein_coding
description:
  SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]


ensembl_gene_id: Spro_3696
symbol: Spro_3696
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ent:Ent638_0144 transcriptional regulator, LysR family.


ensembl_gene_id: Spro_3699
symbol: Spro_3699
gene_biotype: protein_coding
description:
  TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: ypi:YpsIP31758_3067 acriflavine resistance protein A; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: Spro_3700
symbol: Spro_3700
gene_biotype: protein_coding
description:
  TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: stm:STM0475 RND family, acridine efflux pump.


ensembl_gene_id: Spro_3712
symbol: Spro_3712
gene_biotype: protein_coding
description:
  Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: yen:YE0935 AraC-family transcriptional regulator.


ensembl_gene_id: Spro_3714
symbol: Spro_3714
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ent:Ent638_1086 transcriptional regulator, LysR family.


ensembl_gene_id: Spro_3715
symbol: Spro_3715
gene_biotype: protein_coding
description:
  PFAM: major facilitator superfamily MFS_1; KEGG: ent:Ent638_1087 major facilitator superfamily MFS_1.


ensembl_gene_id: Spro_3719
symbol: Spro_3719
gene_biotype: protein_coding
description:
  PFAM: regulatory protein GntR HTH; aminotransferase class I and II; KEGG: yen:YE0931 putative GntR-family transcriptional regulatory protein.


ensembl_gene_id: Spro_3720
symbol: Spro_3720
gene_biotype: protein_coding
description:
  Alkylhydroperoxidase like protein, AhpD family; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.


ensembl_gene_id: Spro_3721
symbol: Spro_3721
gene_biotype: protein_coding
description:
  TIGRFAM: glutaredoxin-like protein NrdH; PFAM: glutaredoxin; KEGG: ypi:YpsIP31758_1065 glutaredoxin-related protein NrdH.


ensembl_gene_id: Spro_3724
symbol: Spro_3724
gene_biotype: protein_coding
description:
  Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.


ensembl_gene_id: Spro_3726
symbol: Spro_3726
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF1289; KEGG: pol:Bpro_4154 YbaK/prolyl-tRNA synthetase associated region.


ensembl_gene_id: Spro_3727
symbol: Spro_3727
gene_biotype: protein_coding
description:
  PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: xau:Xaut_1016 short-chain dehydrogenase/reductase SDR.


ensembl_gene_id: Spro_3728
symbol: Spro_3728
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: rle:RL3780 putative LysR family transcriptional regulator.


ensembl_gene_id: Spro_3731
symbol: Spro_3731
gene_biotype: protein_coding
description:
  Signal transduction histidine kinase regulating citrate/malate metabolism; PFAM: ATP-binding region ATPase domain protein; SMART: PAS domain containing protein; KEGG: eca:ECA2577 two-component sensor kinase.


ensembl_gene_id: Spro_3732
symbol: Spro_3732
gene_biotype: protein_coding
description:
  Response regulator receiver and unknown domain protein; PFAM: response regulator receiver; KEGG: eca:ECA2578 two-component response regulator.


ensembl_gene_id: Spro_3733
symbol: Spro_3733
gene_biotype: protein_coding
description:
  KEGG: yen:YE0925 glycine betaine/L-proline transport ATP-binding protein; TIGRFAM: glycine betaine/L-proline ABC transporter, ATPase subunit; PFAM: CBS domain containing protein; ABC transporter related; SMART: AAA ATPase.


ensembl_gene_id: Spro_3734
symbol: Spro_3734
gene_biotype: protein_coding
description:
  PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eca:ECA3503 glycine betaine/L-proline transport system permease protein.


ensembl_gene_id: Spro_3735
symbol: Spro_3735
gene_biotype: protein_coding
description:
  PFAM: Substrate-binding region of ABC-type glycine betaine transport system; KEGG: ypi:YpsIP31758_1059 glycine betaine/L-proline ABC transporter, periplasmic glycine betaine-binding protein.


ensembl_gene_id: Spro_3736
symbol: Spro_3736
gene_biotype: protein_coding
description:
  PFAM: Substrate-binding region of ABC-type glycine betaine transport system; KEGG: eca:ECA3504 glycine betaine-binding periplasmic protein precursor.


ensembl_gene_id: Spro_3737
symbol: Spro_3737
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: pen:PSEEN1556 transcriptional regulator, LysR family.


ensembl_gene_id: Spro_3742
symbol: Spro_3742
gene_biotype: protein_coding
description:
  TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein; KEGG: yen:YE3241 probable outer membrane efflux protein.


ensembl_gene_id: Spro_3743
symbol: Spro_3743
gene_biotype: protein_coding
description:
  TIGRFAM: efflux pump membrane protein; PFAM: secretion protein HlyD family protein; KEGG: yen:YE3242 multidrug resistance protein A.


ensembl_gene_id: Spro_3744
symbol: Spro_3744
gene_biotype: protein_coding
description:
  TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: ypi:YpsIP31758_3202 multidrug resistance protein B.


ensembl_gene_id: Spro_3745
symbol: Spro_3745
gene_biotype: protein_coding
description:
  PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase substrate binding; KEGG: yen:YE3244 putative tRNA/rRNA methyltransferase; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.


ensembl_gene_id: Spro_3746
symbol: Spro_3746
gene_biotype: protein_coding
description:
  TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: ypi:YpsIP31758_3204 thioredoxin 2; Belongs to the thioredoxin family.


ensembl_gene_id: Spro_3748
symbol: Spro_3748
gene_biotype: protein_coding
description:
  PFAM: GCN5-related N-acetyltransferase; CoA-binding domain protein; KEGG: yps:YPTB0851 putative acyl-CoA synthetase, NAD(P)-binding, ATP-binding.


ensembl_gene_id: Spro_3749
symbol: Spro_3749
gene_biotype: protein_coding
description:
  PFAM: phospholipase D/Transphosphatidylase; KEGG: yen:YE3248 CDP-diacylglycerol--serine O-phosphatidyltransferase.


ensembl_gene_id: Spro_3751
symbol: Spro_3751
gene_biotype: protein_coding
description:
  TIGRFAM: metabolite/H+ symporter, major facilitator superfamily (MFS); PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: eca:ECA3522 alpha-ketoglutarate permease.


ensembl_gene_id: Spro_3752
symbol: Spro_3752
gene_biotype: protein_coding
description:
  TIGRFAM: D,D-heptose 1,7-bisphosphate phosphatase; histidinol-phosphate phosphatase family protein; hydrolase, HAD-superfamily, subfamily IIIA; KEGG: ypi:YpsIP31758_1044 D,D-heptose 1,7-bisphosphate phosphatase.


ensembl_gene_id: Spro_3753
symbol: metN-2
gene_biotype: protein_coding
description:
  D-methionine ABC transporter, ATPase subunit; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.


ensembl_gene_id: Spro_3754
symbol: Spro_3754
gene_biotype: protein_coding
description:
  PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ypi:YpsIP31758_1042 D-methionine ABC transporter, permease protein.


ensembl_gene_id: Spro_3755
symbol: Spro_3755
gene_biotype: protein_coding
description:
  TIGRFAM: lipoprotein, YaeC family; PFAM: NLPA lipoprotein; KEGG: yen:YE3255 putative lipoprotein; Belongs to the nlpA lipoprotein family.


ensembl_gene_id: Spro_3756
symbol: rcsF
gene_biotype: protein_coding
description:
  Putative lipoprotein; Essential component of the Rcs signaling system, which controls transcription of numerous genes. Plays a role in signal transduction from the cell surface to the histidine kinase RcsC. May detect outer membrane defects; Belongs to the RcsF family.


ensembl_gene_id: Spro_3758
symbol: proS
gene_biotype: protein_coding
description:
  prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...]


ensembl_gene_id: Spro_3762
symbol: Spro_3762
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function UPF0253; KEGG: ypi:YpsIP31758_1034 hypothetical protein; Belongs to the UPF0253 family.


ensembl_gene_id: Spro_3763
symbol: Spro_3763
gene_biotype: protein_coding
description:
  Transcriptional antiterminator, Rof; PFAM: Modulator of Rho-dependent transcription termination; KEGG: sbo:SBO_0177 hypothetical protein.


ensembl_gene_id: Spro_3765
symbol: tilS
gene_biotype: protein_coding
description:
  tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.


ensembl_gene_id: Spro_3766
symbol: Spro_3766
gene_biotype: protein_coding
description:
  Amino acid/peptide transporter; KEGG: kpn:KPN_00501 putative di-/tripeptide transport protein (POT family); TIGRFAM: amino acid/peptide transporter; PFAM: TGF-beta receptor type I/II extracellular region; major facilitator superfamily MFS_1.


ensembl_gene_id: Spro_3767
symbol: Spro_3767
gene_biotype: protein_coding
description:
  PFAM: Orn/Lys/Arg decarboxylase major region; Orn/Lys/Arg decarboxylase domain protein; KEGG: kpn:KPN_00500 lysine decarboxylase 1.


ensembl_gene_id: Spro_3768
symbol: Spro_3768
gene_biotype: protein_coding
description:
  PFAM: amino acid permease-associated region; KEGG: kpn:KPN_00499 lysine/cadaverine transport protein (APC family).


ensembl_gene_id: Spro_3769
symbol: Spro_3769
gene_biotype: protein_coding
description:
  Transcriptional regulator, CadC; PFAM: transcriptional regulator domain protein; KEGG: kpn:KPN_00498 transcriptional activator of cad operon.


ensembl_gene_id: Spro_3772
symbol: Spro_3772
gene_biotype: protein_coding
description:
  Transcriptional regulator, MarR family; PFAM: regulatory protein MarR; regulatory protein Crp; regulatory protein ArsR; KEGG: pau:PA14_52070 probable transcriptional regulator.


ensembl_gene_id: Spro_3773
symbol: Spro_3773
gene_biotype: protein_coding
description:
  PFAM: Orn/Lys/Arg decarboxylase major region; Orn/Lys/Arg decarboxylase domain protein; KEGG: yen:YE3267 lysine decarboxylase, constitutive.


ensembl_gene_id: Spro_3774
symbol: accA
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.


ensembl_gene_id: Spro_3775
symbol: Spro_3775
gene_biotype: protein_coding
description:
  KEGG: ypi:YpsIP31758_1028 DNA polymerase III, alpha subunit; TIGRFAM: DNA polymerase III, alpha subunit; PFAM: PHP domain protein; nucleic acid binding OB-fold tRNA/helicase-type; DNA polymerase III alpha subunit; SMART: phosphoesterase PHP domain protein.


ensembl_gene_id: Spro_3776
symbol: rnhB
gene_biotype: protein_coding
description:
  Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.


ensembl_gene_id: Spro_3777
symbol: lpxB
gene_biotype: protein_coding
description:
  lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: Spro_3779
symbol: fabZ
gene_biotype: protein_coding
description:
  Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.


ensembl_gene_id: Spro_3780
symbol: lpxD
gene_biotype: protein_coding
description:
  UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O- (hydroxytetradecanoyl)glucosamine using 3-hydroxytetradecanoyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell; Belongs to the transferase hexapeptide repeat family. LpxD subfamily.


ensembl_gene_id: Spro_3781
symbol: Spro_3781
gene_biotype: protein_coding
description:
  PFAM: outer membrane chaperone Skp (OmpH); KEGG: yps:YPTB2994 cationic 19 kDa outer membrane protein precursor; Belongs to the skp family.


ensembl_gene_id: Spro_3782
symbol: bamA
gene_biotype: protein_coding
description:
  Surface antigen (D15); Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamD, the core component of the assembly machinery.


ensembl_gene_id: Spro_3783
symbol: Spro_3783
gene_biotype: protein_coding
description:
  TIGRFAM: putative membrane-associated zinc metalloprotease; PFAM: PDZ/DHR/GLGF domain protein; peptidase M50; KEGG: yen:YE3277 hypothetical protein.


ensembl_gene_id: Spro_3784
symbol: Spro_3784
gene_biotype: protein_coding
description:
  PFAM: phosphatidate cytidylyltransferase; KEGG: yen:YE3278 phosphatidate cytidylyltransferase; Belongs to the CDS family.


ensembl_gene_id: Spro_3785
symbol: uppS
gene_biotype: protein_coding
description:
  Undecaprenyl diphosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.


ensembl_gene_id: Spro_3786
symbol: dxr
gene_biotype: protein_coding
description:
  1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP).


ensembl_gene_id: Spro_3787
symbol: frr
gene_biotype: protein_coding
description:
  Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.


ensembl_gene_id: Spro_3789
symbol: tsf
gene_biotype: protein_coding
description:
  Translation elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.


ensembl_gene_id: Spro_3790
symbol: rpsB
gene_biotype: protein_coding
description:
  PFAM: ribosomal protein S2; KEGG: ypi:YpsIP31758_1013 ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.


ensembl_gene_id: Spro_3792
symbol: glnD
gene_biotype: protein_coding
description:
  UTP-GlnB uridylyltransferase, GlnD; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.


ensembl_gene_id: Spro_3793
symbol: dapD
gene_biotype: protein_coding
description:
  TIGRFAM: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; KEGG: ssn:SSON_0178 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family.


ensembl_gene_id: Spro_3798
symbol: Spro_3798
gene_biotype: protein_coding
description:
  PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: bxe:Bxe_A0282 major facilitator superfamily (MFS) transporter.


ensembl_gene_id: Spro_3799
symbol: syd
gene_biotype: protein_coding
description:
  Syd family protein; Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function. Belongs to the Syd family.


ensembl_gene_id: Spro_3800
symbol: queF
gene_biotype: protein_coding
description:
  GTP cyclohydrolase I; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).


ensembl_gene_id: Spro_3802
symbol: xni
gene_biotype: protein_coding
description:
  5'-3' exonuclease; Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.


ensembl_gene_id: Spro_3803
symbol: rlmM
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.


ensembl_gene_id: Spro_3805
symbol: Spro_3805
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ypi:YpsIP31758_0999 glycine cleavage system transcriptional activator.


ensembl_gene_id: Spro_3810
symbol: Spro_3810
gene_biotype: protein_coding
description:
  MltA domain protein; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division.


ensembl_gene_id: Spro_3811
symbol: Spro_3811
gene_biotype: protein_coding
description:
  N-acetylmuramoyl-L-alanine amidase; PFAM: cell wall hydrolase/autolysin; KEGG: yen:YE3307 N-acetylmuramoyl-L-alanine amidase AmiC precursor.


ensembl_gene_id: Spro_3812
symbol: argA
gene_biotype: protein_coding
description:
  TIGRFAM: amino-acid N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; aspartate/glutamate/uridylate kinase; KEGG: yen:YE3308 amino-acid acetyltransferase; Belongs to the acetyltransferase family. ArgA subfamily.


ensembl_gene_id: Spro_3813
symbol: recD
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease V, alpha subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and r [...]


ensembl_gene_id: Spro_3814
symbol: recB
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease V, beta subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and re [...]


ensembl_gene_id: Spro_3815
symbol: Spro_3815
gene_biotype: protein_coding
description:
  PFAM: peptidase M16 domain protein; KEGG: yen:YE3311 protease III precursor; Belongs to the peptidase M16 family.


ensembl_gene_id: Spro_3816
symbol: recC
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease V, gamma subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and r [...]


ensembl_gene_id: Spro_3821
symbol: thyA
gene_biotype: protein_coding
description:
  Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.


ensembl_gene_id: Spro_3822
symbol: lgt
gene_biotype: protein_coding
description:
  Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.


ensembl_gene_id: Spro_3823
symbol: Spro_3823
gene_biotype: protein_coding
description:
  PTSINtr with GAF domain, PtsP; TIGRFAM: phosphoenolpyruvate-protein phosphotransferase; PFAM: PEP-utilizing protein; GAF domain protein; PEP-utilising protein mobile region; PEP-utilising protein domain protein; KEGG: yen:YE3319 phosphoenolpyruvate-protein phosphotransferase; Belongs to the PEP-utilizing enzyme family.


ensembl_gene_id: Spro_3824
symbol: rppH
gene_biotype: protein_coding
description:
  NUDIX hydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily.


ensembl_gene_id: Spro_3825
symbol: mutH
gene_biotype: protein_coding
description:
  DNA mismatch repair endonuclease mutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair; Belongs to the MutH family.


ensembl_gene_id: Spro_3829
symbol: lplT
gene_biotype: protein_coding
description:
  Major facilitator superfamily MFS_1; Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell; Belongs to the major facilitator superfamily. LplT (TC 2.A.1.42) family.


ensembl_gene_id: Spro_3830
symbol: aas
gene_biotype: protein_coding
description:
  AMP-dependent synthetase and ligase; Plays a role in lysophospholipid acylation. Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1; In the C-terminal section; belongs to the ATP-dependent AMP-binding enzyme family.


ensembl_gene_id: Spro_3831
symbol: Spro_3831
gene_biotype: protein_coding
description:
  PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; KEGG: yen:YE3330 putative biotin sulfoxide reductas2; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: Spro_3832
symbol: Spro_3832
gene_biotype: protein_coding
description:
  Transcriptional regulator, LacI family; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: yen:YE3331 galactose operon repressor.


ensembl_gene_id: Spro_3834
symbol: Spro_3834
gene_biotype: protein_coding
description:
  Transcriptional regulator, LacI family; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: eca:ECA3649 transcriptional repressor of carbon metabolism.


ensembl_gene_id: Spro_3835
symbol: Spro_3835
gene_biotype: protein_coding
description:
  Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; KEGG: mmw:Mmwyl1_0665 putative transcriptional regulator, XRE family.


ensembl_gene_id: Spro_3836
symbol: lysA
gene_biotype: protein_coding
description:
  Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.


ensembl_gene_id: Spro_3837
symbol: Spro_3837
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: yen:YE3333 transcriptional activator protein LysR.


ensembl_gene_id: Spro_3838
symbol: Spro_3838
gene_biotype: protein_coding
description:
  PFAM: major facilitator superfamily MFS_1; KEGG: ypi:YpsIP31758_0971 transporter, major facilitator family.


ensembl_gene_id: Spro_3839
symbol: Spro_3839
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ypi:YpsIP31758_0969 substrate-binding transcriptional regulator, LysR family.


ensembl_gene_id: Spro_3843
symbol: Spro_3843
gene_biotype: protein_coding
description:
  PFAM: ABC transporter related; SbmABacA family protein; ABC transporter domain protein; SMART: AAA ATPase; KEGG: mms:mma_0271 ABC-type transport system, permease and ATPase components.


ensembl_gene_id: Spro_3844
symbol: Spro_3844
gene_biotype: protein_coding
description:
  PFAM: PTS system fructose subfamily IIA component; KEGG: plu:plu0838 unnamed protein product; similar to putative PTS system IIA component YadI of Escherichia coli.


ensembl_gene_id: Spro_3845
symbol: Spro_3845
gene_biotype: protein_coding
description:
  PFAM: PTS system mannose/fructose/sorbose family IID component; KEGG: plu:plu0837 PTS system, N-acetylgalactosamine-specific IID component (EIID-AGA) (N-acetylgalactosamine-permease IID component) (phosphotransferase enzyme II, D component).


ensembl_gene_id: Spro_3846
symbol: Spro_3846
gene_biotype: protein_coding
description:
  PFAM: phosphotransferase system PTS sorbose-specific IIC subunit; KEGG: plu:plu0836 PTS system, N-acetylgalactosamine-specific IIC component 1 (EIIC-AGA) (N-acetylgalactosamine-permease IIC component 1).


ensembl_gene_id: Spro_3847
symbol: Spro_3847
gene_biotype: protein_coding
description:
  KEGG: plu:plu0835 PTS system, N-acetylgalactosamine-specific IIB component 2 (EIIB-AGA') (N-acetylgalactosamine-permease IIB component 2) (phosphotransferase enzyme II, B component 2); TIGRFAM: PTS system, mannose/fructose/sorbose family, IIB subunit; PFAM: PTS system sorbose subfamily IIB component.


ensembl_gene_id: Spro_3848
symbol: Spro_3848
gene_biotype: protein_coding
description:
  Tagatose-6-phosphate kinase; PFAM: D-tagatose-bisphosphate aldolase class II accessory protein AgaZ; KEGG: plu:plu0833 putative tagatose 6-phosphate kinase AgaZ.


ensembl_gene_id: Spro_3850
symbol: Spro_3850
gene_biotype: protein_coding
description:
  PFAM: major facilitator superfamily MFS_1; KEGG: stm:STM1278 putative MFS family transport protein (amino acid/amine transport).


ensembl_gene_id: Spro_3852
symbol: Spro_3852
gene_biotype: protein_coding
description:
  KEGG: csa:Csal_1039 cyclic peptide transporter; TIGRFAM: cyclic peptide transporter; PFAM: ABC transporter related; SMART: AAA ATPase.


ensembl_gene_id: Spro_3853
symbol: Spro_3853
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: pin:Ping_1689 transcriptional regulator, substrate-binding of LysR family protein.


ensembl_gene_id: Spro_3854
symbol: Spro_3854
gene_biotype: protein_coding
description:
  L-lactate transport; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family.


ensembl_gene_id: Spro_3855
symbol: lldD
gene_biotype: protein_coding
description:
  FMN-dependent alpha-hydroxy acid dehydrogenase; Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain; Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.


ensembl_gene_id: Spro_3856
symbol: Spro_3856
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: kpn:KPN_02460 putative transcriptional regulator (LysR family).


ensembl_gene_id: Spro_3858
symbol: Spro_3858
gene_biotype: protein_coding
description:
  ABC transporter-related protein; PFAM: ABC transporter transmembrane region; ABC transporter related; SMART: AAA ATPase; KEGG: yps:YPTB1082 putative ABC transport protein with fused ATP binding and permease domains.


ensembl_gene_id: Spro_3860
symbol: cbpA
gene_biotype: protein_coding
description:
  Chaperone DnaJ domain protein; DNA-binding protein that preferentially recognizes a curved DNA sequence. It is probably a functional analog of DnaJ; displays overlapping activities with DnaJ, but functions under different conditions, probably acting as a molecular chaperone in an adaptive response to environmental stresses other than heat shock. Lacks autonomous chaperone activity; binds native substrates and targets them for recognition by DnaK. Its activity is inhibited by the binding of CbpM.


ensembl_gene_id: Spro_3862
symbol: Spro_3862
gene_biotype: protein_coding
description:
  PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: ent:Ent638_0201 putative cold-shock DNA-binding domain protein.


ensembl_gene_id: Spro_3864
symbol: Spro_3864
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: mms:mma_0767 transcriptional regulator, LysR family.


ensembl_gene_id: Spro_3865
symbol: Spro_3865
gene_biotype: protein_coding
description:
  PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: pmy:Pmen_4578 short-chain dehydrogenase/reductase SDR; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: Spro_3866
symbol: Spro_3866
gene_biotype: protein_coding
description:
  PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: ava:Ava_3459 short-chain dehydrogenase/reductase SDR.


ensembl_gene_id: Spro_3867
symbol: Spro_3867
gene_biotype: protein_coding
description:
  PFAM: aldehyde dehydrogenase; KEGG: ppu:PP_2487 aldehyde dehydrogenase family protein; Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: Spro_3869
symbol: Spro_3869
gene_biotype: protein_coding
description:
  KEGG: vpa:VP1253 NifS-related protein; TIGRFAM: cysteine desulfurase family protein; PFAM: aminotransferase class V.


ensembl_gene_id: Spro_3870
symbol: Spro_3870
gene_biotype: protein_coding
description:
  Phage transcriptional regulator, AlpA; PFAM: Prophage CP4-57 regulatory; KEGG: ecv:APECO1_4024 putative phage regulatory protein.


ensembl_gene_id: Spro_3885
symbol: Spro_3885
gene_biotype: protein_coding
description:
  Phage transcriptional regulator, AlpA; PFAM: Prophage CP4-57 regulatory; KEGG: yen:YE0975A hypothetical protein.


ensembl_gene_id: Spro_3887
symbol: Spro_3887
gene_biotype: protein_coding
description:
  PFAM: integrase family protein; KEGG: ypn:YPN_3086 integrase; Belongs to the 'phage' integrase family.


ensembl_gene_id: Spro_3888
symbol: lysS
gene_biotype: protein_coding
description:
  TIGRFAM: lysyl-tRNA synthetase; PFAM: tRNA synthetase class II (D K and N); nucleic acid binding OB-fold tRNA/helicase-type; KEGG: kpn:KPN_03318 lysyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family.


ensembl_gene_id: Spro_3890
symbol: Spro_3890
gene_biotype: protein_coding
description:
  TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; KEGG: yen:YE3378 single-stranded-DNA-specific exonuclease.


ensembl_gene_id: Spro_3891
symbol: Spro_3891
gene_biotype: protein_coding
description:
  Thiol:disulfide interchange protein DsbC; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily.


ensembl_gene_id: Spro_3892
symbol: xerD
gene_biotype: protein_coding
description:
  Tyrosine recombinase XerD; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerC binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerD specifically exchanges t [...]


ensembl_gene_id: Spro_3895
symbol: Spro_3895
gene_biotype: protein_coding
description:
  Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: yen:YE3383 putative histidine kinase sensor.


ensembl_gene_id: Spro_3896
symbol: Spro_3896
gene_biotype: protein_coding
description:
  Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: yps:YPTB3171 putative response regulator CreB family.


ensembl_gene_id: Spro_3899
symbol: Spro_3899
gene_biotype: protein_coding
description:
  Glycine cleavage T protein (aminomethyl transferase); Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication; Belongs to the tRNA-modifying YgfZ family.


ensembl_gene_id: Spro_3900
symbol: Spro_3900
gene_biotype: protein_coding
description:
  TIGRFAM: channel protein, hemolysin III family; PFAM: Hly-III family protein; KEGG: yps:YPTB3176 putative hemolysin III.


ensembl_gene_id: Spro_3902
symbol: Spro_3902
gene_biotype: protein_coding
description:
  PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: bch:Bcen2424_4787 major facilitator superfamily MFS_1.


ensembl_gene_id: Spro_3906
symbol: Spro_3906
gene_biotype: protein_coding
description:
  Transcriptional regulator, GntR family; PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: xau:Xaut_0040 transcriptional regulator, GntR family.


ensembl_gene_id: Spro_3909
symbol: Spro_3909
gene_biotype: protein_coding
description:
  PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: kpn:KPN_03338 putative oxidoreductase.


ensembl_gene_id: Spro_3910
symbol: Spro_3910
gene_biotype: protein_coding
description:
  Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: bch:Bcen2424_4924 two component transcriptional regulator, winged helix family.


ensembl_gene_id: Spro_3911
symbol: Spro_3911
gene_biotype: protein_coding
description:
  Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: eba:ebA6233 sensor histidine kinase.


ensembl_gene_id: Spro_3912
symbol: Spro_3912
gene_biotype: protein_coding
description:
  PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: swi:Swit_2294 alcohol dehydrogenase, zinc-binding domain protein.


ensembl_gene_id: Spro_3913
symbol: Spro_3913
gene_biotype: protein_coding
description:
  TIGRFAM: outer membrane autotransporter barrel domain; PFAM: Autotransporter beta- domain protein; KEGG: dps:DP0247 similar to serine protease.


ensembl_gene_id: Spro_3914
symbol: gcvP
gene_biotype: protein_coding
description:
  Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.


ensembl_gene_id: Spro_3915
symbol: gcvH
gene_biotype: protein_coding
description:
  Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.


ensembl_gene_id: Spro_3916
symbol: gcvT
gene_biotype: protein_coding
description:
  Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine.


ensembl_gene_id: Spro_3917
symbol: Spro_3917
gene_biotype: protein_coding
description:
  TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; PFAM: monooxygenase FAD-binding; FAD dependent oxidoreductase; KEGG: yen:YE3394 putative monooxygenase.


ensembl_gene_id: Spro_3918
symbol: Spro_3918
gene_biotype: protein_coding
description:
  2-polyprenyl-6-methoxyphenol 4-hydroxylase; TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; 2-polyprenyl-6-methoxyphenol 4-hydroxylase; PFAM: monooxygenase FAD-binding; FAD dependent oxidoreductase; KEGG: ypi:YpsIP31758_0861 2-polyprenyl-6-methoxyphenol 4-hydroxylase.


ensembl_gene_id: Spro_3919
symbol: Spro_3919
gene_biotype: protein_coding
description:
  PFAM: peptidase M24; peptidase M24B X-Pro dipeptidase/aminopeptidase domain protein; KEGG: ypi:YpsIP31758_0860 Xaa-Pro aminopeptidase.


ensembl_gene_id: Spro_3920
symbol: Spro_3920
gene_biotype: protein_coding
description:
  TIGRFAM: yecA family protein; PFAM: protein of unknown function UPF0149; KEGG: ypi:YpsIP31758_0859 YecA family protein; Belongs to the UPF0149 family.


ensembl_gene_id: Spro_3921
symbol: zapA
gene_biotype: protein_coding
description:
  Protein of unknown function DUF710; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.


ensembl_gene_id: Spro_3922
symbol: Spro_3922
gene_biotype: protein_coding
description:
  PFAM: 5-formyltetrahydrofolate cyclo-ligase; KEGG: ypp:YPDSF_0601 5-formyltetrahydrofolate cyclo-ligase-family protein; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.


ensembl_gene_id: Spro_3923
symbol: Spro_3923
gene_biotype: protein_coding
description:
  PFAM: amino acid-binding ACT domain protein; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: yen:YE3400 D-3-phosphoglycerate dehydrogenase.


ensembl_gene_id: Spro_3924
symbol: rpiA
gene_biotype: protein_coding
description:
  Ribose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.


ensembl_gene_id: Spro_3925
symbol: argP
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; Controls the transcription of genes involved in arginine and lysine metabolism; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Spro_3927
symbol: argO
gene_biotype: protein_coding
description:
  L-lysine exporter; Involved in the export of arginine. Important to control the intracellular level of arginine and the correct balance between arginine and lysine; Belongs to the LysE/ArgO transporter (TC 2.A.75) family.


ensembl_gene_id: Spro_3928
symbol: Spro_3928
gene_biotype: protein_coding
description:
  PFAM: regulatory protein IclR; Transcriptional regulator IclR; KEGG: ecv:APECO1_2876 predicted DNA-binding transcriptional repressor.


ensembl_gene_id: Spro_3929
symbol: Spro_3929
gene_biotype: protein_coding
description:
  ABC transporter-related protein; PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: pmu:PM1251 ribose transport ATP-binding protein.


ensembl_gene_id: Spro_3930
symbol: Spro_3930
gene_biotype: protein_coding
description:
  Monosaccharide-transporting ATPase; PFAM: inner-membrane translocator; KEGG: pmu:PM1250 ribose transport system permease.


ensembl_gene_id: Spro_3932
symbol: Spro_3932
gene_biotype: protein_coding
description:
  Gluconolactonase; PFAM: SMP-30/Gluconolaconase/LRE domain protein; KEGG: pmu:PM1248 gluconolactonase.


ensembl_gene_id: Spro_3933
symbol: dlgD
gene_biotype: protein_coding
description:
  Malate/L-lactate dehydrogenase; Catalyzes the reduction of 2,3-diketo-L-gulonate in the presence of NADH, to form 3-keto-L-gulonate.


ensembl_gene_id: Spro_3936
symbol: Spro_3936
gene_biotype: protein_coding
description:
  PFAM: carbohydrate kinase FGGY; KEGG: eci:UTI89_C4124 cryptic L-xylulose kinase; Belongs to the FGGY kinase family.


ensembl_gene_id: Spro_3937
symbol: Spro_3937
gene_biotype: protein_coding
description:
  PFAM: Orotidine 5'-phosphate decarboxylase; KEGG: spt:SPA3526 putative hexulose-6-phosphate synthase.


ensembl_gene_id: Spro_3938
symbol: Spro_3938
gene_biotype: protein_coding
description:
  KEGG: sec:SC3602 putative 3-hexulose-6-phosphate isomerase; TIGRFAM: putative hexulose-6-phosphate isomerase; PFAM: Xylose isomerase domain protein TIM barrel.


ensembl_gene_id: Spro_3939
symbol: Spro_3939
gene_biotype: protein_coding
description:
  KEGG: yps:YPTB2152 L-ribulose-5-phosphate 4-epimerase; TIGRFAM: L-ribulose-5-phosphate 4-epimerase; PFAM: class II aldolase/adducin family protein.


ensembl_gene_id: Spro_3940
symbol: Spro_3940
gene_biotype: protein_coding
description:
  PFAM: pseudouridine synthase; KEGG: yen:YE2636 putative ribosomal large subunit pseudouridine synthase.


ensembl_gene_id: Spro_3941
symbol: Spro_3941
gene_biotype: protein_coding
description:
  PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: rso:RS01667 putative 4-hydroxybenzoate transporter transmembrane protein.


ensembl_gene_id: Spro_3942
symbol: Spro_3942
gene_biotype: protein_coding
description:
  PFAM: MscS Mechanosensitive ion channel; Conserved TM helix repeat-containing protein; KEGG: ypi:YpsIP31758_0851 transporter, small conductance mechanosensitive ion channel (MscS) family.


ensembl_gene_id: Spro_3944
symbol: Spro_3944
gene_biotype: protein_coding
description:
  Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.


ensembl_gene_id: Spro_3945
symbol: pgk
gene_biotype: protein_coding
description:
  PFAM: phosphoglycerate kinase; KEGG: yen:YE3414 phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.


ensembl_gene_id: Spro_3946
symbol: epd
gene_biotype: protein_coding
description:
  D-erythrose-4-phosphate dehydrogenase; Catalyzes the NAD-dependent conversion of D-erythrose 4- phosphate to 4-phosphoerythronate.


ensembl_gene_id: Spro_3947
symbol: Spro_3947
gene_biotype: protein_coding
description:
  ABC transporter-related protein; PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: yps:YPTB2770 probable ABC transporter, ATP-binding subunit; Belongs to the ABC transporter superfamily.


ensembl_gene_id: Spro_3948
symbol: Spro_3948
gene_biotype: protein_coding
description:
  PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ypi:YpsIP31758_1259 ABC transporter, permease protein.


ensembl_gene_id: Spro_3949
symbol: Spro_3949
gene_biotype: protein_coding
description:
  PFAM: extracellular solute-binding protein family 1; KEGG: yps:YPTB2772 putative ABC transporter, periplasmmic iron binding protein.


ensembl_gene_id: Spro_3950
symbol: Spro_3950
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF6 transmembrane; KEGG: aav:Aave_1958 protein of unknown function DUF6, transmembrane.


ensembl_gene_id: Spro_3951
symbol: Spro_3951
gene_biotype: protein_coding
description:
  TIGRFAM: export-related chaperone CsaA; PFAM: t-RNA-binding domain protein; KEGG: bcy:Bcer98_3652 export-related chaperone CsaA.


ensembl_gene_id: Spro_3956
symbol: Spro_3956
gene_biotype: protein_coding
description:
  PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: kpn:KPN_03360 putative pyruvate decarboxylase; Belongs to the TPP enzyme family.


ensembl_gene_id: Spro_3957
symbol: Spro_3957
gene_biotype: protein_coding
description:
  PFAM: aldehyde dehydrogenase; KEGG: kpn:KPN_03361 putative aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: Spro_3958
symbol: nadX
gene_biotype: protein_coding
description:
  Aspartate dehydrogenase; Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.


ensembl_gene_id: Spro_3959
symbol: Spro_3959
gene_biotype: protein_coding
description:
  PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: kpn:KPN_03363 putative short-chain dehydrogenase.


ensembl_gene_id: Spro_3963
symbol: Spro_3963
gene_biotype: protein_coding
description:
  PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: kpn:KPN_03366 putative ferredoxin reductase subunit.


ensembl_gene_id: Spro_3964
symbol: Spro_3964
gene_biotype: protein_coding
description:
  PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: kpn:KPN_03367 putative glyoxalase/bleomycin resistance protein/dioxygenas.


ensembl_gene_id: Spro_3965
symbol: Spro_3965
gene_biotype: protein_coding
description:
  PFAM: regulatory protein IclR; Transcriptional regulator IclR; KEGG: kpn:KPN_03368 putative bacterial regulatory proteins, IclR.


ensembl_gene_id: Spro_3966
symbol: Spro_3966
gene_biotype: protein_coding
description:
  PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: kpn:KPN_03369 putative short-chain dehydrogenase.


ensembl_gene_id: Spro_3967
symbol: Spro_3967
gene_biotype: protein_coding
description:
  PFAM: Rieske [2Fe-2S] domain protein; KEGG: kpn:KPN_03370 3-phenylpropionate dioxygenase, alpha subunit.


ensembl_gene_id: Spro_3971
symbol: Spro_3971
gene_biotype: protein_coding
description:
  Pseudouridine synthase; PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: ent:Ent638_0226 pseudouridine synthase; Belongs to the pseudouridine synthase RsuA family.


ensembl_gene_id: Spro_3972
symbol: speB
gene_biotype: protein_coding
description:
  Putative agmatinase; Catalyzes the formation of putrescine from agmatine. Belongs to the arginase family. Agmatinase subfamily.


ensembl_gene_id: Spro_3974
symbol: metK
gene_biotype: protein_coding
description:
  Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.


ensembl_gene_id: Spro_3976
symbol: Spro_3976
gene_biotype: protein_coding
description:
  PFAM: transport system permease protein; KEGG: yen:YE0732 ferrichrome transport system permease protein FhuB; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: Spro_3977
symbol: Spro_3977
gene_biotype: protein_coding
description:
  PFAM: periplasmic binding protein; KEGG: ypp:YPDSF_2966 ferrichrome-binding periplasmic protein precursor.


ensembl_gene_id: Spro_3978
symbol: Spro_3978
gene_biotype: protein_coding
description:
  ABC transporter-related protein; PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: eca:ECA3312 ferrichrome transport ATP-binding protein.


ensembl_gene_id: Spro_3979
symbol: Spro_3979
gene_biotype: protein_coding
description:
  TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: kpn:KPN_00165 outer membrane pore protein, receptor for ferrichrome, colicin M, and phages T1, T5 and phi80.


ensembl_gene_id: Spro_3981
symbol: Spro_3981
gene_biotype: protein_coding
description:
  Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).


ensembl_gene_id: Spro_3982
symbol: Spro_3982
gene_biotype: protein_coding
description:
  KEGG: ypn:YPN_0696 ATP-dependent helicase; TIGRFAM: ATP-dependent helicase HrpB; PFAM: helicase domain protein; helicase-associated domain protein; DEAD/DEAH box helicase domain protein; Helicase ATP-dependent domain protein; SMART: DEAD-like helicases.


ensembl_gene_id: Spro_3983
symbol: Spro_3983
gene_biotype: protein_coding
description:
  2'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family.


ensembl_gene_id: Spro_3984
symbol: sfsA
gene_biotype: protein_coding
description:
  PFAM: sugar fermentation stimulation protein; KEGG: ypi:YpsIP31758_3337 sugar fermentation stimulation protein; Belongs to the SfsA family.


ensembl_gene_id: Spro_3985
symbol: dksA
gene_biotype: protein_coding
description:
  Transcriptional regulator, TraR/DksA family; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.


ensembl_gene_id: Spro_3986
symbol: gluQ
gene_biotype: protein_coding
description:
  Glutamate--tRNA ligase; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.


ensembl_gene_id: Spro_3987
symbol: pcnB
gene_biotype: protein_coding
description:
  poly(A) polymerase; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control. Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.


ensembl_gene_id: Spro_3988
symbol: Spro_3988
gene_biotype: protein_coding
description:
  KEGG: ypi:YpsIP31758_3341 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK.


ensembl_gene_id: Spro_3989
symbol: Spro_3989
gene_biotype: protein_coding
description:
  Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: eca:ECA0007 two-component system sensor kinase.


ensembl_gene_id: Spro_3990
symbol: Spro_3990
gene_biotype: protein_coding
description:
  Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: eca:ECA0008 two-component system response regulator.


ensembl_gene_id: Spro_3991
symbol: panB
gene_biotype: protein_coding
description:
  3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.


ensembl_gene_id: Spro_3992
symbol: panC
gene_biotype: protein_coding
description:
  Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.


ensembl_gene_id: Spro_3993
symbol: panD
gene_biotype: protein_coding
description:
  Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.


ensembl_gene_id: Spro_3994
symbol: Spro_3994
gene_biotype: protein_coding
description:
  PFAM: polysaccharide deacetylase; KEGG: ypi:YpsIP31758_3346 polysaccharide deacetylase family protein.


ensembl_gene_id: Spro_3996
symbol: Spro_3996
gene_biotype: protein_coding
description:
  ABC transporter-related protein; PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: yen:YE0715 putative ABC transporter, ATP-binding protein.


ensembl_gene_id: Spro_3998
symbol: Spro_3998
gene_biotype: protein_coding
description:
  KEGG: yps:YPTB0723 hypoxanthine-guanine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.


ensembl_gene_id: Spro_3999
symbol: Spro_3999
gene_biotype: protein_coding
description:
  PFAM: multicopper oxidase type 2; multicopper oxidase type 3; KEGG: yen:YE0712 hypothetical protein.


ensembl_gene_id: Spro_4001
symbol: speE
gene_biotype: protein_coding
description:
  Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.


ensembl_gene_id: Spro_4002
symbol: speD
gene_biotype: protein_coding
description:
  Adenosylmethionine decarboxylase; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.


ensembl_gene_id: Spro_4006
symbol: Spro_4006
gene_biotype: protein_coding
description:
  Phosphopentomutase; PFAM: metalloenzyme domain protein; Phosphopentomutase domain protein; KEGG: yen:YE3104 metalloenzyme superfamily protein.


ensembl_gene_id: Spro_4007
symbol: Spro_4007
gene_biotype: protein_coding
description:
  PFAM: conserved hypothetical protein; KEGG: yen:YE0706 hypothetical protein; Belongs to the UPF0231 family.


ensembl_gene_id: Spro_4008
symbol: Spro_4008
gene_biotype: protein_coding
description:
  PFAM: aconitate hydratase domain protein; aconitate hydratase 2; KEGG: yen:YE0705 aconitate hydratase 2; Belongs to the aconitase/IPM isomerase family.


ensembl_gene_id: Spro_4009
symbol: Spro_4009
gene_biotype: protein_coding
description:
  TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: yen:YE0702 dihydrolipoamide dehydrogenase component of pyruvate dehydrogenase complex.


ensembl_gene_id: Spro_4010
symbol: Spro_4010
gene_biotype: protein_coding
description:
  Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


ensembl_gene_id: Spro_4011
symbol: Spro_4011
gene_biotype: protein_coding
description:
  2-oxo-acid dehydrogenase E1 subunit, homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


ensembl_gene_id: Spro_4012
symbol: Spro_4012
gene_biotype: protein_coding
description:
  PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: yen:YE0698 pyruvate dehydrogenase complex repressor.


ensembl_gene_id: Spro_4013
symbol: Spro_4013
gene_biotype: protein_coding
description:
  PFAM: amino acid permease-associated region; KEGG: yen:YE0695 aromatic amino acid transport protein.


ensembl_gene_id: Spro_4014
symbol: Spro_4014
gene_biotype: protein_coding
description:
  TIGRFAM: sugar (Glycoside-Pentoside-Hexuronide) transporter; PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA3792 hypothetical protein.


ensembl_gene_id: Spro_4015
symbol: Spro_4015
gene_biotype: protein_coding
description:
  Alpha-N-arabinofuranosidase; PFAM: glycoside hydrolase family 43; KEGG: eca:ECA3793 putatuve glycosysl hydrolase; Belongs to the glycosyl hydrolase 43 family.


ensembl_gene_id: Spro_4016
symbol: Spro_4016
gene_biotype: protein_coding
description:
  Gluconate 2-dehydrogenase (acceptor); PFAM: cytochrome c class I; KEGG: rme:Rmet_1417 cytochrome c, class I.


ensembl_gene_id: Spro_4018
symbol: Spro_4018
gene_biotype: protein_coding
description:
  PFAM: aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; KEGG: bur:Bcep18194_B1541 aldehyde oxidase.


ensembl_gene_id: Spro_4022
symbol: Spro_4022
gene_biotype: protein_coding
description:
  Hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.


ensembl_gene_id: Spro_4023
symbol: sprT
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF335 SprT; SMART: protein of unknown function SprT; KEGG: yen:YE3424 hypothetical protein; Belongs to the SprT family.


ensembl_gene_id: Spro_4025
symbol: Spro_4025
gene_biotype: protein_coding
description:
  Protein of unknown function DUF558; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.


ensembl_gene_id: Spro_4026
symbol: gshB
gene_biotype: protein_coding
description:
  KEGG: ypi:YpsIP31758_0836 glutathione synthase; TIGRFAM: glutathione synthetase; PFAM: glutathione synthetase domain protein; glutathione synthetase ATP-binding; RimK domain protein ATP-grasp; Belongs to the prokaryotic GSH synthase family.


ensembl_gene_id: Spro_4027
symbol: Spro_4027
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF179; KEGG: sgl:SG2023 hypothetical protein; Belongs to the UPF0301 (AlgH) family.


ensembl_gene_id: Spro_4028
symbol: yqgF
gene_biotype: protein_coding
description:
  Holliday junction resolvase YqgF; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF nuclease family.


ensembl_gene_id: Spro_4029
symbol: Spro_4029
gene_biotype: protein_coding
description:
  TIGRFAM: twitching motility protein; PFAM: type II secretion system protein E; KEGG: eca:ECA3626 putative type II/IV secretion system protein.


ensembl_gene_id: Spro_4030
symbol: Spro_4030
gene_biotype: protein_coding
description:
  Alanine racemase domain protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.


ensembl_gene_id: Spro_4031
symbol: proC
gene_biotype: protein_coding
description:
  Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.


ensembl_gene_id: Spro_4033
symbol: Spro_4033
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF167; KEGG: yen:YE3436 hypothetical protein; Belongs to the UPF0235 family.


ensembl_gene_id: Spro_4034
symbol: Spro_4034
gene_biotype: protein_coding
description:
  Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.


ensembl_gene_id: Spro_4035
symbol: Spro_4035
gene_biotype: protein_coding
description:
  Putative oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.


ensembl_gene_id: Spro_4042
symbol: trmB
gene_biotype: protein_coding
description:
  tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.


ensembl_gene_id: Spro_4044
symbol: Spro_4044
gene_biotype: protein_coding
description:
  Protein-tyrosine-phosphatase; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes; Belongs to the Fe(2+)-trafficking protein family.


ensembl_gene_id: Spro_4045
symbol: mltC
gene_biotype: protein_coding
description:
  Lytic transglycosylase catalytic; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division.


ensembl_gene_id: Spro_4046
symbol: Spro_4046
gene_biotype: protein_coding
description:
  TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: asa:ASA_3304 GGDEF domain protein.


ensembl_gene_id: Spro_4047
symbol: Spro_4047
gene_biotype: protein_coding
description:
  PFAM: Orn/Lys/Arg decarboxylase major region; Orn/Lys/Arg decarboxylase domain protein; KEGG: ypp:YPDSF_0554 ornithine decarboxylase.


ensembl_gene_id: Spro_4048
symbol: Spro_4048
gene_biotype: protein_coding
description:
  PFAM: integrase family protein; KEGG: eca:ECA0614 putative phage integrase; Belongs to the 'phage' integrase family.


ensembl_gene_id: Spro_4054
symbol: Spro_4054
gene_biotype: protein_coding
description:
  Histidine kinase; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: sec:SC039 hypothetical protein.


ensembl_gene_id: Spro_4065
symbol: Spro_4065
gene_biotype: protein_coding
description:
  TIGRFAM: HAD-superfamily subfamily IIA hydrolase like protein; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: gbe:GbCGDNIH1_1880 hydrolase (HAD superfamily).


ensembl_gene_id: Spro_4070
symbol: Spro_4070
gene_biotype: protein_coding
description:
  PFAM: major facilitator superfamily MFS_1; KEGG: btk:BT9727_3150 possible membrane protein; TGF-beta receptor, type I/II extracellular region.


ensembl_gene_id: Spro_4077
symbol: Spro_4077
gene_biotype: protein_coding
description:
  TIGRFAM: filamentous haemagglutinin family outer membrane protein; adhesin HecA family; PFAM: Haemagluttinin repeat-containing protein; filamentous haemagglutinin domain protein; KEGG: ypi:YpsIP31758_0510 adhesin/haemagluttinin repeat protein.


ensembl_gene_id: Spro_4078
symbol: Spro_4078
gene_biotype: protein_coding
description:
  PFAM: Hemolysin activator HlyB domain protein; Polypeptide-transport-associated domain protein ShlB-type; KEGG: rso:RS02577 probable activation/secretion protein.


ensembl_gene_id: Spro_4082
symbol: Spro_4082
gene_biotype: protein_coding
description:
  TIGRFAM: type I restriction-modification system, M subunit; PFAM: N-6 DNA methylase; KEGG: ypi:YpsIP31758_3536 type I restriction-modification system, M subunit.


ensembl_gene_id: Spro_4083
symbol: Spro_4083
gene_biotype: protein_coding
description:
  PFAM: restriction modification system DNA specificity domain; KEGG: shn:Shewana3_4163 restriction modification system DNA specificity domain.


ensembl_gene_id: Spro_4084
symbol: Spro_4084
gene_biotype: protein_coding
description:
  Type I site-specific deoxyribonuclease, HsdR family; Subunit R is required for both nuclease and ATPase activities, but not for modification.


ensembl_gene_id: Spro_4105
symbol: Spro_4105
gene_biotype: protein_coding
description:
  TIGRFAM: single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; KEGG: yen:YE3844 single-strand binding protein.


ensembl_gene_id: Spro_4118
symbol: Spro_4118
gene_biotype: protein_coding
description:
  Relaxase; PFAM: protein of unknown function DUF1528; Relaxase; KEGG: plu:plu1165 hypothetical protein.


ensembl_gene_id: Spro_4126
symbol: Spro_4126
gene_biotype: protein_coding
description:
  Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; KEGG: yen:YE3496A putative DNA-binding protein.


ensembl_gene_id: Spro_4134
symbol: Spro_4134
gene_biotype: protein_coding
description:
  Transcriptional regulator, CadC; PFAM: transcriptional regulator domain protein; KEGG: eca:ECA0944 hypothetical protein.


ensembl_gene_id: Spro_4150
symbol: Spro_4150
gene_biotype: protein_coding
description:
  Transcriptional regulator, LuxR family; PFAM: regulatory protein LuxR; KEGG: pol:Bpro_4296 two component transcriptional regulator, LuxR family.


ensembl_gene_id: Spro_4152
symbol: Spro_4152
gene_biotype: protein_coding
description:
  PFAM: FKBP-type peptidyl-prolyl isomerase domain protein; peptidylprolyl isomerase FKBP-type; KEGG: kpn:KPN_00128 hypothetical protein.


ensembl_gene_id: Spro_4166
symbol: Spro_4166
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: kpn:KPN_02993 putative transcriptional regulator (LysR family).


ensembl_gene_id: Spro_4195
symbol: Spro_4195
gene_biotype: protein_coding
description:
  Transcriptional regulator, XRE family; SMART: helix-turn-helix domain protein; KEGG: plu:plu1490 hypothetical protein.


ensembl_gene_id: Spro_4198
symbol: Spro_4198
gene_biotype: protein_coding
description:
  Phospholipase C; PFAM: phosphoesterase; protein of unknown function DUF756; KEGG: pfl:PFL_3126 phospholipase C.


ensembl_gene_id: Spro_4199
symbol: Spro_4199
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: plu:plu3727 putative transcriptional regulator AbgR.


ensembl_gene_id: Spro_4200
symbol: Spro_4200
gene_biotype: protein_coding
description:
  TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: plu:plu3726 aminobenzoyl-glutamate utilization protein A.


ensembl_gene_id: Spro_4201
symbol: Spro_4201
gene_biotype: protein_coding
description:
  TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: plu:plu3725 aminobenzoyl-glutamate utilization protein B.


ensembl_gene_id: Spro_4203
symbol: Spro_4203
gene_biotype: protein_coding
description:
  PFAM: PfkB domain protein; KEGG: yen:YE0554 fructokinase; Belongs to the carbohydrate kinase PfkB family.


ensembl_gene_id: Spro_4205
symbol: Spro_4205
gene_biotype: protein_coding
description:
  TIGRFAM: PTS system, sucrose-specific IIBC subunit; PTS system, glucose-like IIB subunint; PFAM: phosphotransferase system PTS EIIB protein; phosphotransferase system EIIC; KEGG: yen:YE0552 PTS system, sucrose-specific IIBC component.


ensembl_gene_id: Spro_4207
symbol: Spro_4207
gene_biotype: protein_coding
description:
  Transcriptional regulator, LacI family; KEGG: yen:YE0550A sucrose operon repressor; TIGRFAM: D-fructose-responsive transcription factor; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator.


ensembl_gene_id: Spro_4209
symbol: Spro_4209
gene_biotype: protein_coding
description:
  TIGRFAM: putative addiction module antidote protein, CC2985 family; PFAM: protein of unknown function UPF0156; KEGG: plu:plu4283 hypothetical protein.


ensembl_gene_id: Spro_4210
symbol: Spro_4210
gene_biotype: protein_coding
description:
  TIGRFAM: TonB system transport protein ExbD type-1; PFAM: Biopolymer transport protein ExbD/TolR; KEGG: plu:plu3940 biopolymer transport protein ExbD.


ensembl_gene_id: Spro_4211
symbol: Spro_4211
gene_biotype: protein_coding
description:
  TIGRFAM: TonB-system energizer ExbB type-1; PFAM: MotA/TolQ/ExbB proton channel; KEGG: ypm:YP_2997 TonB complex protein.


ensembl_gene_id: Spro_4212
symbol: Spro_4212
gene_biotype: protein_coding
description:
  TIGRFAM: cystathionine beta-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: eca:ECA0354 cystathionine beta-lyase.


ensembl_gene_id: Spro_4214
symbol: Spro_4214
gene_biotype: protein_coding
description:
  Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein AraC type; AraC-type transcriptional regulator domain protein; KEGG: yen:YE3649 AraC-family regulatory protein.


ensembl_gene_id: Spro_4215
symbol: Spro_4215
gene_biotype: protein_coding
description:
  PFAM: iron-containing alcohol dehydrogenase; KEGG: eca:ECA0350 putative iron-containing alcohol dehydrogenase.


ensembl_gene_id: Spro_4217
symbol: torD
gene_biotype: protein_coding
description:
  Cytoplasmic chaperone TorD family protein; Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor; Belongs to the TorD/DmsD family. TorD subfamily.


ensembl_gene_id: Spro_4218
symbol: Spro_4218
gene_biotype: protein_coding
description:
  KEGG: ppr:PBPRA1495 putative trimethylamine-N-oxide reductase 1 precursor; TIGRFAM: molybdopterin guanine dinucleotide-containing S/N-oxide reductase; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: Spro_4219
symbol: Spro_4219
gene_biotype: protein_coding
description:
  PFAM: NapC/NirT cytochrome c domain protein; KEGG: ecv:APECO1_89 cytochrome c-type protein TorC; Belongs to the TorC/TorY family.


ensembl_gene_id: Spro_4220
symbol: Spro_4220
gene_biotype: protein_coding
description:
  PFAM: regulatory protein GntR HTH; aminotransferase class I and II; KEGG: pap:PSPA7_3030 transcriptional regulator, GntR family, with aminotransferase domain.


ensembl_gene_id: Spro_4221
symbol: Spro_4221
gene_biotype: protein_coding
description:
  Beta-glucosidase; PFAM: glycoside hydrolase family 1; KEGG: kpn:KPN_01961 6-phospho-beta-glucosidase A.


ensembl_gene_id: Spro_4222
symbol: Spro_4222
gene_biotype: protein_coding
description:
  PFAM: phosphotransferase system PTS lactose/cellobiose-specific IIA subunit; KEGG: vfi:VF0607 PTS system, diacetylchitobiose-specific IIA component.


ensembl_gene_id: Spro_4224
symbol: Spro_4224
gene_biotype: protein_coding
description:
  PFAM: phosphotransferase system lactose/cellobiose-specific IIB subunit; KEGG: eca:ECA4435 pts system, IIb component.


ensembl_gene_id: Spro_4226
symbol: Spro_4226
gene_biotype: protein_coding
description:
  PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: ssn:SSON_2628 putative oxidoreductase.


ensembl_gene_id: Spro_4227
symbol: Spro_4227
gene_biotype: protein_coding
description:
  Monosaccharide-transporting ATPase; PFAM: inner-membrane translocator; KEGG: sbo:SBO_2572 putative transport system permease protein.


ensembl_gene_id: Spro_4228
symbol: Spro_4228
gene_biotype: protein_coding
description:
  ABC transporter-related protein; PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sfv:SFV_2595 putative ATP-binding component of a transport system.


ensembl_gene_id: Spro_4229
symbol: Spro_4229
gene_biotype: protein_coding
description:
  PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: ecc:c3070 ABC transporter Periplasmic binding protein yphF precursor.


ensembl_gene_id: Spro_4230
symbol: Spro_4230
gene_biotype: protein_coding
description:
  Sugar transporter; KEGG: kpn:KPN_02872 putative general substrate transporter; TIGRFAM: sugar transporter; PFAM: General substrate transporter; major facilitator superfamily MFS_1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.


ensembl_gene_id: Spro_4231
symbol: Spro_4231
gene_biotype: protein_coding
description:
  PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: ecv:APECO1_3982 hypothetical protein.


ensembl_gene_id: Spro_4234
symbol: Spro_4234
gene_biotype: protein_coding
description:
  PFAM: Radical SAM domain protein; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: yen:YE3653 hypothetical protein.


ensembl_gene_id: Spro_4236
symbol: Spro_4236
gene_biotype: protein_coding
description:
  Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: bte:BTH_I2369 transcriptional regulator, AraC family domain protein.


ensembl_gene_id: Spro_4239
symbol: Spro_4239
gene_biotype: protein_coding
description:
  PFAM: chitin-binding domain 3 protein; KEGG: asa:ASA_0604 chitin-binding protein, carbohydrate-binding module family 33.


ensembl_gene_id: Spro_4241
symbol: Spro_4241
gene_biotype: protein_coding
description:
  Prepilin peptidase; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.


ensembl_gene_id: Spro_4243
symbol: Spro_4243
gene_biotype: protein_coding
description:
  General secretion pathway L; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.


ensembl_gene_id: Spro_4245
symbol: Spro_4245
gene_biotype: protein_coding
description:
  TIGRFAM: general secretion pathway protein J; KEGG: yen:YE3570a putative general secretion pathway protein J precursor.


ensembl_gene_id: Spro_4246
symbol: Spro_4246
gene_biotype: protein_coding
description:
  TIGRFAM: general secretion pathway protein I; PFAM: type II secretion system protein I/J; KEGG: yen:YE3570 general secretion pathway protein I precursor.


ensembl_gene_id: Spro_4247
symbol: Spro_4247
gene_biotype: protein_coding
description:
  TIGRFAM: general secretion pathway protein H; KEGG: asa:ASA_3779 general secretion pathway protein H.


ensembl_gene_id: Spro_4248
symbol: Spro_4248
gene_biotype: protein_coding
description:
  TIGRFAM: general secretion pathway protein G; PFAM: type II secretion system protein G; KEGG: eca:ECA3106 general secretion pathway protein G.


ensembl_gene_id: Spro_4249
symbol: Spro_4249
gene_biotype: protein_coding
description:
  TIGRFAM: general secretion pathway protein F; PFAM: type II secretion system protein; KEGG: eca:ECA3107 general secretion pathway protein F.


ensembl_gene_id: Spro_4250
symbol: Spro_4250
gene_biotype: protein_coding
description:
  General secretory pathway protein E; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.


ensembl_gene_id: Spro_4251
symbol: Spro_4251
gene_biotype: protein_coding
description:
  TIGRFAM: general secretion pathway protein D; PFAM: type II and III secretion system protein; NolW domain protein; KEGG: kpn:KPN_00160 pullulanase D protein.


ensembl_gene_id: Spro_4254
symbol: Spro_4254
gene_biotype: protein_coding
description:
  TIGRFAM: nucleoside transporter; PFAM: nucleoside:H symporter; major facilitator superfamily MFS_1; KEGG: ypi:YpsIP31758_2823 xanthosine transporter XapB.


ensembl_gene_id: Spro_4255
symbol: Spro_4255
gene_biotype: protein_coding
description:
  Xanthosine phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.


ensembl_gene_id: Spro_4256
symbol: Spro_4256
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sec:SC2417 regulator for XapA (LysR family); Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Spro_4257
symbol: ftsP
gene_biotype: protein_coding
description:
  Multicopper oxidase type 3; Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress; Belongs to the FtsP family.


ensembl_gene_id: Spro_4258
symbol: Spro_4258
gene_biotype: protein_coding
description:
  KEGG: ypi:YpsIP31758_0582 1-acyl-sn-glycerol-3-phosphate acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferase; PFAM: phospholipid/glycerol acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.


ensembl_gene_id: Spro_4259
symbol: parC
gene_biotype: protein_coding
description:
  DNA topoisomerase IV, A subunit; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.


ensembl_gene_id: Spro_4260
symbol: Spro_4260
gene_biotype: protein_coding
description:
  PFAM: NAD(P)H dehydrogenase (quinone); KEGG: ypi:YpsIP31758_0580 putative NADH-quinone reductase MdaB.


ensembl_gene_id: Spro_4262
symbol: Spro_4262
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ypi:YpsIP31758_0579 substrate-binding transcriptional regulator, LysR family.


ensembl_gene_id: Spro_4263
symbol: parE
gene_biotype: protein_coding
description:
  DNA topoisomerase IV, B subunit; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily.


ensembl_gene_id: Spro_4265
symbol: cpdA
gene_biotype: protein_coding
description:
  Calcineurin phosphoesterase domain protein; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.


ensembl_gene_id: Spro_4266
symbol: Spro_4266
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF1249; KEGG: ent:Ent638_3446 protein of unknown function DUF1249.


ensembl_gene_id: Spro_4268
symbol: Spro_4268
gene_biotype: protein_coding
description:
  TIGRFAM: type I secretion outer membrane protein, TolC family; PFAM: outer membrane efflux protein; KEGG: ent:Ent638_3448 type I secretion outer membrane protein, TolC family.


ensembl_gene_id: Spro_4269
symbol: Spro_4269
gene_biotype: protein_coding
description:
  GAF modulated sigma54 specific transcriptional regulator, Fis family; PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; GAF domain protein; PAS fold domain protein; SMART: PAS domain containing protein; KEGG: yen:YE0550 glycerol metabolism operon regulatory protein.


ensembl_gene_id: Spro_4270
symbol: Spro_4270
gene_biotype: protein_coding
description:
  Dihydroxyacetone kinase, phosphotransfer subunit; KEGG: yen:YE0542 multifunctional PTS-system sugar transferase; TIGRFAM: phosphocarrier, HPr family; dihydroxyacetone kinase, phosphotransfer subunit; PFAM: phosphocarrier HPr protein; PTS system fructose subfamily IIA component; PEP-utilising protein mobile region; PEP-utilising protein domain protein; Belongs to the PEP-utilizing enzyme family.


ensembl_gene_id: Spro_4271
symbol: Spro_4271
gene_biotype: protein_coding
description:
  TIGRFAM: dihydroxyacetone kinase, L subunit; PFAM: Dak phosphatase; KEGG: yen:YE0541 hypothetical protein.


ensembl_gene_id: Spro_4272
symbol: Spro_4272
gene_biotype: protein_coding
description:
  Dihydroxyacetone kinase, DhaK subunit; KEGG: yen:YE0540 putative dihydroxyacetone kinase; TIGRFAM: dihydroxyacetone kinase, DhaK subunit; PFAM: Dak kinase.


ensembl_gene_id: Spro_4273
symbol: Spro_4273
gene_biotype: protein_coding
description:
  PFAM: iron-containing alcohol dehydrogenase; 3-dehydroquinate synthase; KEGG: yen:YE0539 glycerol dehydrogenase.


ensembl_gene_id: Spro_4276
symbol: Spro_4276
gene_biotype: protein_coding
description:
  PFAM: glucose-6-phosphate isomerase; Cupin 2 conserved barrel domain protein; KEGG: aha:AHA_2345 glucose-6-phosphate isomerase.


ensembl_gene_id: Spro_4278
symbol: Spro_4278
gene_biotype: protein_coding
description:
  PFAM: PTS system mannose/fructose/sorbose family IID component; KEGG: aha:AHA_2339 fructose permease IID component.


ensembl_gene_id: Spro_4279
symbol: Spro_4279
gene_biotype: protein_coding
description:
  PFAM: phosphotransferase system PTS sorbose-specific IIC subunit; KEGG: aha:AHA_2340 PTS system, fructose(mannose)-specific IIC.


ensembl_gene_id: Spro_4280
symbol: Spro_4280
gene_biotype: protein_coding
description:
  PFAM: PTS system sorbose subfamily IIB component; KEGG: aha:AHA_2341 PTS system mannose-specific EIIAB component (EIIAB-man).


ensembl_gene_id: Spro_4281
symbol: Spro_4281
gene_biotype: protein_coding
description:
  PFAM: PTS system fructose subfamily IIA component; KEGG: aha:AHA_2342 PTS system, mannose/fructose/sorbose family, IIA component.


ensembl_gene_id: Spro_4283
symbol: Spro_4283
gene_biotype: protein_coding
description:
  Transcriptional regulator, LacI family; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: aha:AHA_2344 maltose regulon regulatory protein MalI.


ensembl_gene_id: Spro_4284
symbol: Spro_4284
gene_biotype: protein_coding
description:
  PFAM: Extradiol ring-cleavage dioxygenase class III protein subunit B; KEGG: yen:YE3668 hypothetical protein.


ensembl_gene_id: Spro_4286
symbol: ribB
gene_biotype: protein_coding
description:
  3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.


ensembl_gene_id: Spro_4289
symbol: hldE
gene_biotype: protein_coding
description:
  rfaE bifunctional protein; Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7- phosphate at the C-1 position to selectively form D-glycero-beta-D- manno-heptose-1,7-bisphosphate; In the C-terminal section; belongs to the cytidylyltransferase family.


ensembl_gene_id: Spro_4290
symbol: glnE
gene_biotype: protein_coding
description:
  (Glutamate--ammonia-ligase) adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal tra [...]


ensembl_gene_id: Spro_4293
symbol: cca
gene_biotype: protein_coding
description:
  Polynucleotide adenylyltransferase/metal dependent phosphohydrolase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.


ensembl_gene_id: Spro_4294
symbol: uppP
gene_biotype: protein_coding
description:
  Putative undecaprenol kinase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.


ensembl_gene_id: Spro_4295
symbol: Spro_4295
gene_biotype: protein_coding
description:
  Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.


ensembl_gene_id: Spro_4296
symbol: plsY
gene_biotype: protein_coding
description:
  Protein of unknown function DUF205; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.


ensembl_gene_id: Spro_4297
symbol: tsaD
gene_biotype: protein_coding
description:
  Putative metalloendopeptidase, glycoprotease family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.


ensembl_gene_id: Spro_4298
symbol: rpsU
gene_biotype: protein_coding
description:
  PFAM: ribosomal protein S21; KEGG: kpn:KPN_03472 30S ribosomal protein S21; Belongs to the bacterial ribosomal protein bS21 family.


ensembl_gene_id: Spro_4299
symbol: dnaG
gene_biotype: protein_coding
description:
  DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.


ensembl_gene_id: Spro_4300
symbol: rpoD
gene_biotype: protein_coding
description:
  RNA polymerase, sigma 70 subunit, RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.


ensembl_gene_id: Spro_4301
symbol: mug
gene_biotype: protein_coding
description:
  Uracil-DNA glycosylase superfamily; Excises ethenocytosine and uracil, which can arise by alkylation or deamination of cytosine, respectively, from the corresponding mispairs with guanine in ds-DNA. It is capable of hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of the DNA and the mispaired base. The complementary strand guanine functions in substrate recognition. Required for DNA damage lesion repair in stationary-phase cells; Belongs to the uracil-DNA glycosylase (UDG) superfamily. TDG/mug family.


ensembl_gene_id: Spro_4304
symbol: Spro_4304
gene_biotype: protein_coding
description:
  PFAM: aromatic amino acid permease; Amino acid transporter transmembrane; KEGG: kpn:KPN_03823 probable aromatic amino acid transporter.


ensembl_gene_id: Spro_4305
symbol: Spro_4305
gene_biotype: protein_coding
description:
  TIGRFAM: succinic semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase; KEGG: eca:ECA2054 succinate-semialdehyde dehydrogenase [NADP+]; Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: Spro_4306
symbol: Spro_4306
gene_biotype: protein_coding
description:
  TIGRFAM: 4-aminobutyrate aminotransferase; PFAM: aminotransferase class I and II; aminotransferase class-III; KEGG: kpn:KPN_03825 putative aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: Spro_4307
symbol: Spro_4307
gene_biotype: protein_coding
description:
  PFAM: regulatory protein GntR HTH; aminotransferase class I and II; KEGG: pin:Ping_0569 transcriptional regulator (GntR family) with HTH domain.


ensembl_gene_id: Spro_4308
symbol: Spro_4308
gene_biotype: protein_coding
description:
  ABC transporter-related protein; PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: kpn:KPN_03920 putative ATP-binding component of a transport system.


ensembl_gene_id: Spro_4309
symbol: Spro_4309
gene_biotype: protein_coding
description:
  PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: ypi:YpsIP31758_0501 2,4-dienoyl-coa reductase.


ensembl_gene_id: Spro_4312
symbol: rlmG
gene_biotype: protein_coding
description:
  rRNA (guanine-N(2)-)-methyltransferase; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.


ensembl_gene_id: Spro_4314
symbol: Spro_4314
gene_biotype: protein_coding
description:
  Plasmid maintenance system antidote protein, XRE family; TIGRFAM: addiction module antidote protein, HigA family; PFAM: helix-turn-helix domain protein; KEGG: plu:plu2984 hypothetical protein.


ensembl_gene_id: Spro_4319
symbol: sstT
gene_biotype: protein_coding
description:
  Sodium:dicarboxylate symporter; Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system). Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: Spro_4320
symbol: Spro_4320
gene_biotype: protein_coding
description:
  PFAM: D-galactarate dehydratase/Altronate hydrolase domain protein; SAF domain protein; KEGG: ypi:YpsIP31758_0493 altronate dehydratase.


ensembl_gene_id: Spro_4322
symbol: Spro_4322
gene_biotype: protein_coding
description:
  TIGRFAM: d-galactonate transporter; PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA0644 galacturonate transporter.


ensembl_gene_id: Spro_4323
symbol: Spro_4323
gene_biotype: protein_coding
description:
  PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: yen:YE3710 exu regulon transcriptional regulator.


ensembl_gene_id: Spro_4326
symbol: mzrA
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Modulates the activity of the EnvZ/OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR.


ensembl_gene_id: Spro_4333
symbol: Spro_4333
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: yen:YE3720 LysR-family transcriptional regulatory protein.


ensembl_gene_id: Spro_4335
symbol: rsmI
gene_biotype: protein_coding
description:
  Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.


ensembl_gene_id: Spro_4336
symbol: lpoA
gene_biotype: protein_coding
description:
  LppC family lipoprotein; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a).


ensembl_gene_id: Spro_4337
symbol: Spro_4337
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function UPF0102; KEGG: ypi:YpsIP31758_0474 hypothetical protein; Belongs to the UPF0102 family.


ensembl_gene_id: Spro_4338
symbol: diaA
gene_biotype: protein_coding
description:
  Phosphoheptose isomerase; Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein. Belongs to the SIS family. DiaA subfamily.


ensembl_gene_id: Spro_4339
symbol: Spro_4339
gene_biotype: protein_coding
description:
  PFAM: transport-associated; SMART: Transport-associated and nodulation region; KEGG: eca:ECA0319 putative lipoprotein.


ensembl_gene_id: Spro_4340
symbol: mtgA
gene_biotype: protein_coding
description:
  Monofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family.


ensembl_gene_id: Spro_4341
symbol: Spro_4341
gene_biotype: protein_coding
description:
  ThiJ/PfpI domain protein; Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate; Belongs to the peptidase C56 family.


ensembl_gene_id: Spro_4342
symbol: Spro_4342
gene_biotype: protein_coding
description:
  Multi-sensor hybrid histidine kinase; KEGG: ypi:YpsIP31758_0469 putative aerobic respiration control sensor protein ArcB; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; Hpt domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein.


ensembl_gene_id: Spro_4343
symbol: Spro_4343
gene_biotype: protein_coding
description:
  KEGG: yen:YE3734 hypothetical protein; TIGRFAM: conserved hypothetical radical SAM protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB.


ensembl_gene_id: Spro_4344
symbol: Spro_4344
gene_biotype: protein_coding
description:
  PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: yen:YE3735 glutamate synthase [NADPH] large chain precursor.


ensembl_gene_id: Spro_4345
symbol: Spro_4345
gene_biotype: protein_coding
description:
  TIGRFAM: glutamate synthase, small subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: ypi:YpsIP31758_0465 glutamate synthase, small subunit.


ensembl_gene_id: Spro_4347
symbol: Spro_4347
gene_biotype: protein_coding
description:
  PFAM: Glutathione S-transferase domain; KEGG: yen:YE3739 putative stringent starvation protein A; Belongs to the GST superfamily.


ensembl_gene_id: Spro_4348
symbol: rpsI
gene_biotype: protein_coding
description:
  PFAM: ribosomal protein S9; KEGG: eca:ECA0307 30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.


ensembl_gene_id: Spro_4349
symbol: rplM
gene_biotype: protein_coding
description:
  Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.


ensembl_gene_id: Spro_4352
symbol: Spro_4352
gene_biotype: protein_coding
description:
  Protease Do; KEGG: eca:ECA0303 exported protease; TIGRFAM: protease Do; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; Belongs to the peptidase S1C family.


ensembl_gene_id: Spro_4353
symbol: Spro_4353
gene_biotype: protein_coding
description:
  KEGG: sfv:SFV_3262 protease; TIGRFAM: periplasmic serine protease DegS; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein.


ensembl_gene_id: Spro_4354
symbol: murA
gene_biotype: protein_coding
description:
  UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.


ensembl_gene_id: Spro_4356
symbol: Spro_4356
gene_biotype: protein_coding
description:
  PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: ypi:YpsIP31758_0452 putative anti-anti-sigma factor.


ensembl_gene_id: Spro_4360
symbol: Spro_4360
gene_biotype: protein_coding
description:
  ABC transporter-related protein; PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ypi:YpsIP31758_0448 putative ABC transporter, ATP-binding protein YrbF.


ensembl_gene_id: Spro_4361
symbol: Spro_4361
gene_biotype: protein_coding
description:
  TIGRFAM: Na+/Ca+ antiporter, CaCA family; PFAM: sodium/calcium exchanger membrane region; KEGG: yen:YE3753 putative sodium/calcium exchanger protein.


ensembl_gene_id: Spro_4362
symbol: Spro_4362
gene_biotype: protein_coding
description:
  KpsF/GutQ family protein; KEGG: yen:YE3754 hypothetical protein; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS).


ensembl_gene_id: Spro_4363
symbol: Spro_4363
gene_biotype: protein_coding
description:
  3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family.


ensembl_gene_id: Spro_4364
symbol: lptC
gene_biotype: protein_coding
description:
  Protein of unknown function DUF1239; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family.


ensembl_gene_id: Spro_4365
symbol: lptA
gene_biotype: protein_coding
description:
  Cell envelope biogenesis YhbN; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.


ensembl_gene_id: Spro_4366
symbol: Spro_4366
gene_biotype: protein_coding
description:
  ABC transporter-related protein; PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: yen:YE3758 probable ABC transporter ATP-binding protein.


ensembl_gene_id: Spro_4367
symbol: Spro_4367
gene_biotype: protein_coding
description:
  RNA polymerase, sigma 54 subunit, RpoN; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.


ensembl_gene_id: Spro_4368
symbol: Spro_4368
gene_biotype: protein_coding
description:
  TIGRFAM: ribosomal subunit interface protein; PFAM: sigma 54 modulation protein/ribosomal protein S30EA; KEGG: ypi:YpsIP31758_0440 ribosomal subunit interface protein.


ensembl_gene_id: Spro_4369
symbol: Spro_4369
gene_biotype: protein_coding
description:
  TIGRFAM: PTS IIA-like nitrogen-regulatory protein PtsN; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; KEGG: yen:YE3761 nitrogen regulatory IIA protein.


ensembl_gene_id: Spro_4370
symbol: rapZ
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ. When glucosamine-6- phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E. Consequently, GlmZ is inactivated and unable to activate GlmS synthesis. Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS; Belongs to the RapZ-like family. RapZ subfamily.


ensembl_gene_id: Spro_4371
symbol: Spro_4371
gene_biotype: protein_coding
description:
  TIGRFAM: phosphocarrier, HPr family; PFAM: phosphocarrier HPr protein; KEGG: yen:YE3763 putative phosphocarrier protein.


ensembl_gene_id: Spro_4372
symbol: Spro_4372
gene_biotype: protein_coding
description:
  Transcriptional antiterminator, BglG; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; M trans-acting positive regulator; PRD domain protein; Helix-turn-helix type 11 domain protein; KEGG: yen:YE3777 putative transcriptional regulator.


ensembl_gene_id: Spro_4374
symbol: Spro_4374
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF1341; KEGG: ent:Ent638_0431 protein of unknown function DUF1341.


ensembl_gene_id: Spro_4375
symbol: Spro_4375
gene_biotype: protein_coding
description:
  TIGRFAM: pyridoxal phosphate-dependent enzyme, putative; PFAM: L-seryl-tRNA selenium transferase; KEGG: yen:YE3780 possible L-seryl-tRNA selenocysteine synthase.


ensembl_gene_id: Spro_4387
symbol: Spro_4387
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF615; KEGG: yen:YE3790 hypothetical protein; Belongs to the UPF0307 family.


ensembl_gene_id: Spro_4390
symbol: aaeB
gene_biotype: protein_coding
description:
  Fusaric acid resistance protein conserved region; Forms an efflux pump with AaeA. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell; Belongs to the aromatic acid exporter ArAE (TC 2.A.85) family.


ensembl_gene_id: Spro_4391
symbol: aaeA
gene_biotype: protein_coding
description:
  Efflux transporter, RND family, MFP subunit; Forms an efflux pump with AaeB; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: Spro_4393
symbol: Spro_4393
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: yen:YE3797 probable LysR-family transcriptional regulatory protein.


ensembl_gene_id: Spro_4396
symbol: Spro_4396
gene_biotype: protein_coding
description:
  Purine nucleosidase; PFAM: Inosine/uridine-preferring nucleoside hydrolase; KEGG: aau:AAur_3646 putative inosine-uridine preferring nucleoside hydrolase (IunH); Belongs to the IUNH family.


ensembl_gene_id: Spro_4402
symbol: Spro_4402
gene_biotype: protein_coding
description:
  TIGRFAM: filamentous haemagglutinin family outer membrane protein; adhesin HecA family; PFAM: Haemagluttinin repeat-containing protein; filamentous haemagglutinin domain protein; KEGG: eci:UTI89_C4946 putative member of ShlA/HecA/FhaA exoprotein family.


ensembl_gene_id: Spro_4403
symbol: Spro_4403
gene_biotype: protein_coding
description:
  PFAM: Hemolysin activator HlyB domain protein; Polypeptide-transport-associated domain protein ShlB-type; KEGG: ent:Ent638_0052 polypeptide-transport-associated domain protein, ShlB-type.


ensembl_gene_id: Spro_4405
symbol: Spro_4405
gene_biotype: protein_coding
description:
  PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: ypi:YpsIP31758_0404 hydrolase, carbon-nitrogen family protein.


ensembl_gene_id: Spro_4407
symbol: Spro_4407
gene_biotype: protein_coding
description:
  TIGRFAM: ribonuclease, Rne/Rng family; PFAM: RNA binding S1 domain protein; KEGG: ypi:YpsIP31758_0402 ribonuclease G.


ensembl_gene_id: Spro_4408
symbol: Spro_4408
gene_biotype: protein_coding
description:
  Maf protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.


ensembl_gene_id: Spro_4409
symbol: Spro_4409
gene_biotype: protein_coding
description:
  Rod shape-determining protein MreD; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins. Belongs to the MreD family.


ensembl_gene_id: Spro_4411
symbol: Spro_4411
gene_biotype: protein_coding
description:
  TIGRFAM: cell shape determining protein, MreB/Mrl family; PFAM: cell shape determining protein MreB/Mrl; KEGG: sgl:SG0156 rod shape-determining protein MreB.


ensembl_gene_id: Spro_4412
symbol: Spro_4412
gene_biotype: protein_coding
description:
  TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; KEGG: ypi:YpsIP31758_0397 putative diguanylate cyclase/cyclic diguanylate phosphodiesterase protein.


ensembl_gene_id: Spro_4413
symbol: Spro_4413
gene_biotype: protein_coding
description:
  TIGRFAM: Quinone oxidoreductase putative YhdH/YhfP; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: ypi:YpsIP31758_0396 putative quinone oxidoreductase, YhdH/YhfP family protein.


ensembl_gene_id: Spro_4414
symbol: msrP
gene_biotype: protein_coding
description:
  Oxidoreductase molybdopterin binding; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce b [...]


ensembl_gene_id: Spro_4415
symbol: msrQ
gene_biotype: protein_coding
description:
  Ferric reductase domain protein transmembrane component domain; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the r [...]


ensembl_gene_id: Spro_4417
symbol: Spro_4417
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.


ensembl_gene_id: Spro_4418
symbol: Spro_4418
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.


ensembl_gene_id: Spro_4420
symbol: Spro_4420
gene_biotype: protein_coding
description:
  Sodium/pantothenate symporter; TIGRFAM: SSS sodium solute transporter superfamily; sodium/pantothenate symporter; PFAM: Na+/solute symporter; KEGG: ypi:YpsIP31758_0389 sodium/pantothenate symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: Spro_4421
symbol: prmA
gene_biotype: protein_coding
description:
  Ribosomal protein L11 methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family.


ensembl_gene_id: Spro_4423
symbol: dusB
gene_biotype: protein_coding
description:
  Putative TIM-barrel protein, nifR3 family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily.


ensembl_gene_id: Spro_4424
symbol: fis
gene_biotype: protein_coding
description:
  Transcriptional regulator, Fis family; Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters; Belongs to the transcriptional regulatory Fis family.


ensembl_gene_id: Spro_4425
symbol: lpxP
gene_biotype: protein_coding
description:
  Lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase; Catalyzes the transfer of palmitoleate from palmitoleoyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)- (palmitoleoyl)-lipid IV(A); Belongs to the LpxL/LpxM/LpxP family. LpxP subfamily.


ensembl_gene_id: Spro_4429
symbol: Spro_4429
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: yen:YE3838 putative LysR family transcriptional regulator.


ensembl_gene_id: Spro_4430
symbol: Spro_4430
gene_biotype: protein_coding
description:
  Na+/H+ antiporter; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.


ensembl_gene_id: Spro_4431
symbol: Spro_4431
gene_biotype: protein_coding
description:
  PFAM: Xanthine/uracil/vitamin C permease; sulphate transporter; KEGG: yps:YPTB3600 putative xanthine/uracil permease.


ensembl_gene_id: Spro_4433
symbol: Spro_4433
gene_biotype: protein_coding
description:
  PFAM: Glutathione S-transferase domain; KEGG: yen:YE3841 putative glutathione S transferase; Belongs to the GST superfamily.


ensembl_gene_id: Spro_4436
symbol: Spro_4436
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: mms:mma_1861 transcriptional regulator, LysR family.


ensembl_gene_id: Spro_4437
symbol: Spro_4437
gene_biotype: protein_coding
description:
  PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: mms:mma_1860 oxidoreductase, short chain dehydrogenase/reductase family.


ensembl_gene_id: Spro_4440
symbol: uvrA
gene_biotype: protein_coding
description:
  Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.


ensembl_gene_id: Spro_4441
symbol: Spro_4441
gene_biotype: protein_coding
description:
  PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: bvi:Bcep1808_3188 alcohol dehydrogenase, zinc-binding domain protein.


ensembl_gene_id: Spro_4442
symbol: Spro_4442
gene_biotype: protein_coding
description:
  PFAM: transferase hexapeptide repeat containing protein; KEGG: ent:Ent638_0939 transferase hexapeptide repeat containing protein.


ensembl_gene_id: Spro_4445
symbol: Spro_4445
gene_biotype: protein_coding
description:
  Aromatic-amino-acid transaminase; PFAM: aminotransferase class I and II; KEGG: yps:YPTB0377 aspartate aminotransferase.


ensembl_gene_id: Spro_4447
symbol: Spro_4447
gene_biotype: protein_coding
description:
  Arogenate dehydratase; PFAM: extracellular solute-binding protein family 3; KEGG: pfo:Pfl_3814 extracellular solute-binding protein, family 3; Belongs to the bacterial solute-binding protein 3 family.


ensembl_gene_id: Spro_4450
symbol: Spro_4450
gene_biotype: protein_coding
description:
  PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: eca:ECA3663 quinone oxidoreductase.


ensembl_gene_id: Spro_4453
symbol: dusA
gene_biotype: protein_coding
description:
  TIM-barrel protein, yjbN family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily.


ensembl_gene_id: Spro_4455
symbol: Spro_4455
gene_biotype: protein_coding
description:
  RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: ret:RHE_CH00746 RNA polymerase sigma factor protein (sigma-24); Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: Spro_4457
symbol: Spro_4457
gene_biotype: protein_coding
description:
  Ferric uptake regulator, Fur family; PFAM: ferric-uptake regulator; KEGG: yen:YE3853 putative regulatory protein; Belongs to the Fur family.


ensembl_gene_id: Spro_4458
symbol: Spro_4458
gene_biotype: protein_coding
description:
  PFAM: CsbD family protein; KEGG: yen:YE3854 hypothetical protein; Belongs to the UPF0337 (CsbD) family.


ensembl_gene_id: Spro_4459
symbol: Spro_4459
gene_biotype: protein_coding
description:
  TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: kpn:KPN_04432 DNA-damage-inducible protein F.


ensembl_gene_id: Spro_4460
symbol: lexA
gene_biotype: protein_coding
description:
  Transcriptional repressor, LexA family; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'. In the presence of single- stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.


ensembl_gene_id: Spro_4461
symbol: Spro_4461
gene_biotype: protein_coding
description:
  Diacylglycerol kinase; Recycling of diacylglycerol produced during the turnover of membrane phospholipid.


ensembl_gene_id: Spro_4462
symbol: plsB
gene_biotype: protein_coding
description:
  Glycerol-3-phosphate O-acyltransferase; PFAM: phospholipid/glycerol acyltransferase; KEGG: yen:YE3857 glycerol-3-phosphate acyltransferase; Belongs to the GPAT/DAPAT family.


ensembl_gene_id: Spro_4463
symbol: ubiA
gene_biotype: protein_coding
description:
  4-hydroxybenzoate polyprenyl transferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.


ensembl_gene_id: Spro_4464
symbol: ubiC
gene_biotype: protein_coding
description:
  Chorismate lyase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.


ensembl_gene_id: Spro_4465
symbol: Spro_4465
gene_biotype: protein_coding
description:
  PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: yen:YE3588 putative transporter protein.


ensembl_gene_id: Spro_4466
symbol: Spro_4466
gene_biotype: protein_coding
description:
  KEGG: yen:YE3589 LacI family regulatory protein; PFAM: periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI.


ensembl_gene_id: Spro_4467
symbol: Spro_4467
gene_biotype: protein_coding
description:
  PFAM: Inosine/uridine-preferring nucleoside hydrolase; KEGG: yen:YE3590 putative hydrolase; Belongs to the IUNH family.


ensembl_gene_id: Spro_4469
symbol: lamB
gene_biotype: protein_coding
description:
  Porin LamB type; Involved in the transport of maltose and maltodextrins. Belongs to the porin LamB (TC 1.B.3) family.


ensembl_gene_id: Spro_4470
symbol: malK
gene_biotype: protein_coding
description:
  ABC transporter-related protein; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Maltooligosaccharide importer (TC 3.A.1.1.1) family.


ensembl_gene_id: Spro_4472
symbol: Spro_4472
gene_biotype: protein_coding
description:
  Extracellular solute-binding protein family 1; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Binds maltose and higher maltodextrins. Belongs to the bacterial solute-binding protein 1 family.


ensembl_gene_id: Spro_4473
symbol: Spro_4473
gene_biotype: protein_coding
description:
  PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ypp:YPDSF_0185 maltose transport system permease protein MalF.


ensembl_gene_id: Spro_4474
symbol: Spro_4474
gene_biotype: protein_coding
description:
  PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: yen:YE3868 maltose transport system permease protein MalG.


ensembl_gene_id: Spro_4477
symbol: pgi
gene_biotype: protein_coding
description:
  PFAM: phosphoglucose isomerase (PGI); KEGG: yen:YE3870 glucose-6-phosphate isomerase; Belongs to the GPI family.


ensembl_gene_id: Spro_4478
symbol: Spro_4478
gene_biotype: protein_coding
description:
  PFAM: sodium/hydrogen exchanger; KEGG: asa:ASA_3754 sodium/hydrogen exchanger family protein; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.


ensembl_gene_id: Spro_4479
symbol: Spro_4479
gene_biotype: protein_coding
description:
  Aspartate kinase; KEGG: ypi:YpsIP31758_0301 asparate kinase, monofunctional class; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family.


ensembl_gene_id: Spro_4481
symbol: Spro_4481
gene_biotype: protein_coding
description:
  PFAM: Hemolysin activator HlyB domain protein; Polypeptide-transport-associated domain protein ShlB-type; KEGG: plu:plu0317 PhlA hemolysin secretion/activation protein PhlB.


ensembl_gene_id: Spro_4482
symbol: Spro_4482
gene_biotype: protein_coding
description:
  TIGRFAM: filamentous haemagglutinin family outer membrane protein; PFAM: Haemagluttinin repeat-containing protein; filamentous haemagglutinin domain protein; KEGG: yps:YPTB3652 hemolysin.


ensembl_gene_id: Spro_4483
symbol: Spro_4483
gene_biotype: protein_coding
description:
  TIGRFAM: sodium-dependent inorganic phosphate (Pi) transporter; Na/Pi-cotransporter II-related protein; PFAM: Na+/Picotransporter; KEGG: eca:ECA3983 putative sodium/phosphate cotransporter.


ensembl_gene_id: Spro_4484
symbol: Spro_4484
gene_biotype: protein_coding
description:
  ABC transporter-related protein; PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: pau:PA14_21910 putative ATP-binding component of ABC transporter; Belongs to the ABC transporter superfamily.


ensembl_gene_id: Spro_4485
symbol: Spro_4485
gene_biotype: protein_coding
description:
  PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: pap:PSPA7_1872 probable permease of ABC transporter.


ensembl_gene_id: Spro_4486
symbol: Spro_4486
gene_biotype: protein_coding
description:
  PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: pfl:PFL_4389 ABC transporter, permease protein.


ensembl_gene_id: Spro_4488
symbol: Spro_4488
gene_biotype: protein_coding
description:
  PFAM: extracellular solute-binding protein family 1; KEGG: pau:PA14_21960 putative ABC transporter, periplasmic substrate-binding protein.


ensembl_gene_id: Spro_4489
symbol: Spro_4489
gene_biotype: protein_coding
description:
  Transcriptional regulator, GntR family; PFAM: regulatory protein GntR HTH; UbiC transcription regulator-associated domain protein; KEGG: pmy:Pmen_1333 transcriptional regulator, GntR family.


ensembl_gene_id: Spro_4490
symbol: Spro_4490
gene_biotype: protein_coding
description:
  Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.


ensembl_gene_id: Spro_4491
symbol: Spro_4491
gene_biotype: protein_coding
description:
  PFAM: regulatory protein IclR; Transcriptional regulator IclR; KEGG: ypi:YpsIP31758_0297 acetate operon repressor.


ensembl_gene_id: Spro_4496
symbol: Spro_4496
gene_biotype: protein_coding
description:
  Acid phosphatase; PFAM: phosphoesterase PA-phosphatase related; KEGG: reh:H16_B1238 acid phosphatase.


ensembl_gene_id: Spro_4497
symbol: Spro_4497
gene_biotype: protein_coding
description:
  KEGG: stm:STM3542 gluconate kinase 2; TIGRFAM: carbohydrate kinase, thermoresistant glucokinase family; PFAM: shikimate kinase.


ensembl_gene_id: Spro_4498
symbol: Spro_4498
gene_biotype: protein_coding
description:
  TIGRFAM: gluconate transporter; PFAM: Gluconate transporter; Citrate transporter; KEGG: plu:plu0498 low-affinity gluconate transporter (gluconate permease) (Gnt-I system).


ensembl_gene_id: Spro_4499
symbol: edd
gene_biotype: protein_coding
description:
  6-phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family.


ensembl_gene_id: Spro_4500
symbol: Spro_4500
gene_biotype: protein_coding
description:
  KEGG: stm:STM1884 keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase; TIGRFAM: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; PFAM: KDPG and KHG aldolase.


ensembl_gene_id: Spro_4501
symbol: aceK
gene_biotype: protein_coding
description:
  (Isocitrate dehydrogenase (NADP(+))) kinase; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.


ensembl_gene_id: Spro_4502
symbol: Spro_4502
gene_biotype: protein_coding
description:
  TIGRFAM: isocitrate lyase; PFAM: isocitrate lyase and phosphorylmutase; KEGG: ypi:YpsIP31758_0295 isocitrate lyase.


ensembl_gene_id: Spro_4503
symbol: Spro_4503
gene_biotype: protein_coding
description:
  KEGG: ypi:YpsIP31758_0294 malate synthase A; TIGRFAM: malate synthase A; PFAM: malate synthase; Belongs to the malate synthase family.


ensembl_gene_id: Spro_4504
symbol: metAS
gene_biotype: protein_coding
description:
  Homoserine O-succinyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine; Belongs to the MetA family.


ensembl_gene_id: Spro_4506
symbol: aroE
gene_biotype: protein_coding
description:
  Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).


ensembl_gene_id: Spro_4507
symbol: tsaC
gene_biotype: protein_coding
description:
  SUA5/yciO/yrdC domain; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.


ensembl_gene_id: Spro_4508
symbol: Spro_4508
gene_biotype: protein_coding
description:
  PFAM: DNA topoisomerase type IA zn finger domain protein; KEGG: kpn:KPN_03684 putative DNA topoisomerase.


ensembl_gene_id: Spro_4510
symbol: Spro_4510
gene_biotype: protein_coding
description:
  TIGRFAM: DNA protecting protein DprA; PFAM: SMF family protein; KEGG: yen:YE3888 hypothetical protein.


ensembl_gene_id: Spro_4511
symbol: def
gene_biotype: protein_coding
description:
  Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.


ensembl_gene_id: Spro_4512
symbol: fmt
gene_biotype: protein_coding
description:
  methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.


ensembl_gene_id: Spro_4514
symbol: Spro_4514
gene_biotype: protein_coding
description:
  PFAM: TrkA-N domain protein; NADP oxidoreductase coenzyme F420-dependent; TrkA-C domain protein; KEGG: ypi:YpsIP31758_3885 trk system potassium uptake protein TrkA.


ensembl_gene_id: Spro_4515
symbol: mscL
gene_biotype: protein_coding
description:
  Large conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.


ensembl_gene_id: Spro_4517
symbol: Spro_4517
gene_biotype: protein_coding
description:
  Transcriptional regulator, MerR family; TIGRFAM: Zn(II)-responsive transcriptional regulator; PFAM: regulatory protein MerR; Transcription regulator MerR DNA binding; KEGG: yen:YE3895 MerR-family transcriptional regulator.


ensembl_gene_id: Spro_4519
symbol: rpoA
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: Spro_4520
symbol: rpsD
gene_biotype: protein_coding
description:
  Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.


ensembl_gene_id: Spro_4521
symbol: rpsK
gene_biotype: protein_coding
description:
  Ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.


ensembl_gene_id: Spro_4522
symbol: rpsM
gene_biotype: protein_coding
description:
  Ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family.


ensembl_gene_id: Spro_4524
symbol: secY
gene_biotype: protein_coding
description:
  Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.


ensembl_gene_id: Spro_4525
symbol: rplO
gene_biotype: protein_coding
description:
  Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.


ensembl_gene_id: Spro_4527
symbol: rpsE
gene_biotype: protein_coding
description:
  Ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family.


ensembl_gene_id: Spro_4528
symbol: rplR
gene_biotype: protein_coding
description:
  Ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.


ensembl_gene_id: Spro_4529
symbol: rplF
gene_biotype: protein_coding
description:
  Ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.


ensembl_gene_id: Spro_4530
symbol: rpsH
gene_biotype: protein_coding
description:
  Ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.


ensembl_gene_id: Spro_4531
symbol: rpsN
gene_biotype: protein_coding
description:
  Ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family.


ensembl_gene_id: Spro_4532
symbol: rplE
gene_biotype: protein_coding
description:
  Ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.


ensembl_gene_id: Spro_4533
symbol: rplX
gene_biotype: protein_coding
description:
  Ribosomal protein L24; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.


ensembl_gene_id: Spro_4534
symbol: rplN
gene_biotype: protein_coding
description:
  Ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.


ensembl_gene_id: Spro_4535
symbol: rpsQ
gene_biotype: protein_coding
description:
  Ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.


ensembl_gene_id: Spro_4536
symbol: rpmC
gene_biotype: protein_coding
description:
  PFAM: ribosomal protein L29; KEGG: ypi:YpsIP31758_3907 ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family.


ensembl_gene_id: Spro_4537
symbol: rplP
gene_biotype: protein_coding
description:
  Ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.


ensembl_gene_id: Spro_4538
symbol: rpsC
gene_biotype: protein_coding
description:
  Ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.


ensembl_gene_id: Spro_4539
symbol: rplV
gene_biotype: protein_coding
description:
  Ribosomal protein L22; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).


ensembl_gene_id: Spro_4540
symbol: Spro_4540
gene_biotype: protein_coding
description:
  PFAM: ribosomal protein S19/S15; KEGG: plu:plu4722 30S ribosomal protein S19; Belongs to the universal ribosomal protein uS19 family.


ensembl_gene_id: Spro_4541
symbol: rplB
gene_biotype: protein_coding
description:
  Ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.


ensembl_gene_id: Spro_4542
symbol: rplW
gene_biotype: protein_coding
description:
  Ribosomal protein L25/L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.


ensembl_gene_id: Spro_4543
symbol: rplD
gene_biotype: protein_coding
description:
  Ribosomal protein L4/L1e; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.


ensembl_gene_id: Spro_4544
symbol: rplC
gene_biotype: protein_coding
description:
  Ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.


ensembl_gene_id: Spro_4545
symbol: rpsJ
gene_biotype: protein_coding
description:
  Ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.


ensembl_gene_id: Spro_4546
symbol: Spro_4546
gene_biotype: protein_coding
description:
  Bacterioferritin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family.


ensembl_gene_id: Spro_4547
symbol: Spro_4547
gene_biotype: protein_coding
description:
  PFAM: BFD domain protein [2Fe-2S]-binding domain protein; KEGG: yps:YPTB3701 putative bacterioferritin-associated ferredoxin.


ensembl_gene_id: Spro_4550
symbol: rpsG
gene_biotype: protein_coding
description:
  Ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.


ensembl_gene_id: Spro_4552
symbol: tusB
gene_biotype: protein_coding
description:
  DsrH family protein; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.


ensembl_gene_id: Spro_4553
symbol: tusC
gene_biotype: protein_coding
description:
  DsrE family protein; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.


ensembl_gene_id: Spro_4554
symbol: tusD
gene_biotype: protein_coding
description:
  DsrE family protein; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE.


ensembl_gene_id: Spro_4556
symbol: Spro_4556
gene_biotype: protein_coding
description:
  PFAM: FKBP-type peptidyl-prolyl isomerase domain protein; peptidylprolyl isomerase FKBP-type; KEGG: yen:YE3935 peptidyl-prolyl cis-trans isomerase.


ensembl_gene_id: Spro_4558
symbol: Spro_4558
gene_biotype: protein_coding
description:
  PFAM: peptidylprolyl isomerase FKBP-type; KEGG: ent:Ent638_3766 peptidylprolyl isomerase, FKBP-type.


ensembl_gene_id: Spro_4561
symbol: kefG
gene_biotype: protein_coding
description:
  NAD(P)H dehydrogenase (quinone); Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefB.


ensembl_gene_id: Spro_4562
symbol: Spro_4562
gene_biotype: protein_coding
description:
  ABC transporter-related protein; PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: yen:YE3942 putative ATPase component of an ABC transporter.


ensembl_gene_id: Spro_4564
symbol: Spro_4564
gene_biotype: protein_coding
description:
  PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ypi:YpsIP31758_3936 taurine ABC transporter, permease protein.


ensembl_gene_id: Spro_4565
symbol: tauB
gene_biotype: protein_coding
description:
  ABC transporter-related protein; Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Taurine importer (TC 3.A.1.17.1) family.


ensembl_gene_id: Spro_4566
symbol: Spro_4566
gene_biotype: protein_coding
description:
  KEGG: yen:YE3948 putative taurine-binding periplasmic protein precursor; TIGRFAM: taurine ABC transporter, periplasmic binding protein; PFAM: Substrate-binding region of ABC-type glycine betaine transport system; SMART: extracellular solute-binding protein family 3.


ensembl_gene_id: Spro_4567
symbol: Spro_4567
gene_biotype: protein_coding
description:
  PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: bra:BRADO0445 putative oxidoreductase/dehydrogenase protein.


ensembl_gene_id: Spro_4568
symbol: Spro_4568
gene_biotype: protein_coding
description:
  PFAM: AP endonuclease 2 domain protein; Xylose isomerase domain protein TIM barrel; KEGG: kpn:KPN_00539 putative xylose isomerase-like TIM barrel.


ensembl_gene_id: Spro_4569
symbol: Spro_4569
gene_biotype: protein_coding
description:
  PFAM: oxidoreductase domain protein; homoserine dehydrogenase NAD-binding; KEGG: rba:RB3338 probable myo-inositol 2-dehydrogenase.


ensembl_gene_id: Spro_4570
symbol: Spro_4570
gene_biotype: protein_coding
description:
  PFAM: nucleoside:H symporter; major facilitator superfamily MFS_1; KEGG: asu:Asuc_0358 nucleoside:H symporter.


ensembl_gene_id: Spro_4573
symbol: Spro_4573
gene_biotype: protein_coding
description:
  Transcriptional regulator, LacI family; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: eca:ECA1397 LacI-family transcriptional regulator.


ensembl_gene_id: Spro_4574
symbol: Spro_4574
gene_biotype: protein_coding
description:
  TIGRFAM: phenazine biosynthesis protein PhzF family; PFAM: Phenazine biosynthesis PhzC/PhzF protein; KEGG: yen:YE3949 hypothetical protein.


ensembl_gene_id: Spro_4577
symbol: Spro_4577
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function UPF0270; KEGG: yen:YE3952 hypothetical protein; Belongs to the UPF0270 family.


ensembl_gene_id: Spro_4580
symbol: Spro_4580
gene_biotype: protein_coding
description:
  Transcriptional regulator, Crp/Fnr family; PFAM: cyclic nucleotide-binding; regulatory protein Crp; KEGG: eca:ECA4064 cyclic AMP receptor protein.


ensembl_gene_id: Spro_4581
symbol: Spro_4581
gene_biotype: protein_coding
description:
  TIGRFAM: integral membrane protein, YccS/YhfK family; PFAM: protein of unknown function DUF893 YccS/YhfK; KEGG: ent:Ent638_3785 integral membrane protein, YccS/YhfK family.


ensembl_gene_id: Spro_4583
symbol: Spro_4583
gene_biotype: protein_coding
description:
  TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: yen:YE3958 para-aminobenzoate synthase glutamine amidotransferase component II.


ensembl_gene_id: Spro_4584
symbol: Spro_4584
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF853 NPT hydrolase putative; KEGG: ypi:YpsIP31758_3949 hypothetical protein.


ensembl_gene_id: Spro_4586
symbol: Spro_4586
gene_biotype: protein_coding
description:
  TIGRFAM: addiction module toxin, RelE/StbE family; PFAM: plasmid stabilization system; KEGG: neu:NE0552 hypothetical protein.


ensembl_gene_id: Spro_4587
symbol: Spro_4587
gene_biotype: protein_coding
description:
  PFAM: response regulator receiver; LytTr DNA-binding region; KEGG: ent:Ent638_2723 two component transcriptional regulator, LytTR family.


ensembl_gene_id: Spro_4588
symbol: Spro_4588
gene_biotype: protein_coding
description:
  Signal transduction histidine kinase, LytS; PFAM: ATP-binding region ATPase domain protein; histidine kinase internal region; 5TM Receptors of the LytS-YhcK type transmembrane region; SMART: GAF domain protein; KEGG: ecv:APECO1_4423 putative sensory kinase in two-component system with YehT.


ensembl_gene_id: Spro_4590
symbol: Spro_4590
gene_biotype: protein_coding
description:
  PFAM: phosphotransferase system PTS lactose/cellobiose-specific IIA subunit; KEGG: plu:plu2756 PTS system, cellobiose-specific IIA component (EIIA-CEL) (cellobiose-permease IIA component) (phosphotransferase enzyme II, A component) (EIII-CEL).


ensembl_gene_id: Spro_4592
symbol: Spro_4592
gene_biotype: protein_coding
description:
  Transcriptional regulator, LacI family; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: ypi:YpsIP31758_3952 sugar-binding transcriptional regulator, LacI family.


ensembl_gene_id: Spro_4594
symbol: Spro_4594
gene_biotype: protein_coding
description:
  N-isopropylammelide isopropylaminohydrolase; PFAM: amidohydrolase; Amidohydrolase 3; KEGG: yen:YE3964 cytosine deaminase.


ensembl_gene_id: Spro_4595
symbol: Spro_4595
gene_biotype: protein_coding
description:
  TIGRFAM: nitrite reductase [NAD(P)H], large subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein; nitrite and sulphite reductase 4Fe-4S region; BFD domain protein [2Fe-2S]-binding domain protein; KEGG: yen:YE3965 nitrite reductase.


ensembl_gene_id: Spro_4599
symbol: trpS
gene_biotype: protein_coding
description:
  tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: Spro_4600
symbol: gph
gene_biotype: protein_coding
description:
  Phosphoglycolate phosphatase; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.


ensembl_gene_id: Spro_4601
symbol: Spro_4601
gene_biotype: protein_coding
description:
  PFAM: ribulose-phosphate 3-epimerase; KEGG: stm:STM3483 ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.


ensembl_gene_id: Spro_4602
symbol: Spro_4602
gene_biotype: protein_coding
description:
  KEGG: yen:YE3972 DNA adenine methylase; TIGRFAM: DNA adenine methylase; PFAM: D12 class N6 adenine-specific DNA methyltransferase.


ensembl_gene_id: Spro_4604
symbol: aroB
gene_biotype: protein_coding
description:
  3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.


ensembl_gene_id: Spro_4605
symbol: aroK
gene_biotype: protein_coding
description:
  Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.


ensembl_gene_id: Spro_4606
symbol: Spro_4606
gene_biotype: protein_coding
description:
  TIGRFAM: type IV pilus secretin PilQ; PFAM: type II and III secretion system protein; NolW domain protein; KEGG: ypi:YpsIP31758_3967 protein transporter HofQ.


ensembl_gene_id: Spro_4611
symbol: Spro_4611
gene_biotype: protein_coding
description:
  TIGRFAM: penicillin-binding protein, 1A family; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; KEGG: yen:YE3979 penicillin-binding protein.


ensembl_gene_id: Spro_4614
symbol: Spro_4614
gene_biotype: protein_coding
description:
  TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: yen:YE3983 hypothetical protein.


ensembl_gene_id: Spro_4615
symbol: Spro_4615
gene_biotype: protein_coding
description:
  PFAM: RNA-binding S4 domain protein; KEGG: yen:YE3984 heat shock protein 15; Belongs to the HSP15 family.


ensembl_gene_id: Spro_4616
symbol: hslO
gene_biotype: protein_coding
description:
  Hsp33 protein; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.


ensembl_gene_id: Spro_4620
symbol: Spro_4620
gene_biotype: protein_coding
description:
  Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: yen:YE4005 osmolarity sensor protein.


ensembl_gene_id: Spro_4621
symbol: Spro_4621
gene_biotype: protein_coding
description:
  Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: yen:YE4004 transcriptional regulatory protein.


ensembl_gene_id: Spro_4622
symbol: Spro_4622
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: rso:RSc2243 probable transcription regulator protein; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Spro_4625
symbol: Spro_4625
gene_biotype: protein_coding
description:
  5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: pna:Pnap_2474 5-carboxymethyl-2-hydroxymuconate delta-isomerase.


ensembl_gene_id: Spro_4626
symbol: greB
gene_biotype: protein_coding
description:
  Transcription elongation factor GreB; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.


ensembl_gene_id: Spro_4627
symbol: Spro_4627
gene_biotype: protein_coding
description:
  PFAM: RNA binding S1 domain protein; SMART: Resolvase RNase H domain protein fold; KEGG: yen:YE4000 putative transcription accessory protein.


ensembl_gene_id: Spro_4629
symbol: Spro_4629
gene_biotype: protein_coding
description:
  Ferrous iron transport protein B; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.


ensembl_gene_id: Spro_4630
symbol: feoC
gene_biotype: protein_coding
description:
  Protein of unknown function DUF1920; May function as a transcriptional regulator that controls feoABC expression.


ensembl_gene_id: Spro_4632
symbol: bioH
gene_biotype: protein_coding
description:
  bioH protein; The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.


ensembl_gene_id: Spro_4634
symbol: nfuA
gene_biotype: protein_coding
description:
  HesB/YadR/YfhF-family protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.


ensembl_gene_id: Spro_4635
symbol: Spro_4635
gene_biotype: protein_coding
description:
  KEGG: yen:YE3992 4-alpha-glucanotransferase; TIGRFAM: 4-alpha-glucanotransferase; PFAM: glycoside hydrolase family 77.


ensembl_gene_id: Spro_4636
symbol: Spro_4636
gene_biotype: protein_coding
description:
  Glycogen/starch/alpha-glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.


ensembl_gene_id: Spro_4637
symbol: malT
gene_biotype: protein_coding
description:
  ATP-dependent transcriptional regulator, MalT-like, LuxR family; Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto- oligosaccharides. Specifically binds to the promoter region of its target genes, recognizing a short DNA motif called the MalT box.


ensembl_gene_id: Spro_4638
symbol: glpE
gene_biotype: protein_coding
description:
  Rhodanese domain protein; Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.


ensembl_gene_id: Spro_4640
symbol: Spro_4640
gene_biotype: protein_coding
description:
  Transcriptional regulator, DeoR family; PFAM: regulatory protein DeoR; Helix-turn-helix type 11 domain protein; KEGG: yen:YE3987 glycerol-3-phosphate repressor protein.


ensembl_gene_id: Spro_4642
symbol: Spro_4642
gene_biotype: protein_coding
description:
  PFAM: FAD dependent oxidoreductase; KEGG: yen:YE4008 aerobic glycerol-3-phosphate dehydrogenase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.


ensembl_gene_id: Spro_4645
symbol: glgC
gene_biotype: protein_coding
description:
  Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.


ensembl_gene_id: Spro_4646
symbol: glgX
gene_biotype: protein_coding
description:
  Glycogen debranching enzyme GlgX; Removes maltotriose and maltotetraose chains that are attached by 1,6-alpha-linkage to the limit dextrin main chain, generating a debranched limit dextrin.


ensembl_gene_id: Spro_4647
symbol: glgB
gene_biotype: protein_coding
description:
  1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.


ensembl_gene_id: Spro_4648
symbol: asd
gene_biotype: protein_coding
description:
  Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.


ensembl_gene_id: Spro_4649
symbol: Spro_4649
gene_biotype: protein_coding
description:
  PFAM: multiple antibiotic resistance (MarC)-related protein; KEGG: yps:YPTB3791 possible MarC family transporter.


ensembl_gene_id: Spro_4650
symbol: Spro_4650
gene_biotype: protein_coding
description:
  KEGG: sgl:SG2151 putative gluconokinase; TIGRFAM: carbohydrate kinase, thermoresistant glucokinase family; PFAM: shikimate kinase.


ensembl_gene_id: Spro_4651
symbol: Spro_4651
gene_biotype: protein_coding
description:
  TIGRFAM: gluconate transporter; PFAM: Gluconate transporter; Citrate transporter; KEGG: ypp:YPDSF_3319 gluconate permease.


ensembl_gene_id: Spro_4652
symbol: Spro_4652
gene_biotype: protein_coding
description:
  Transcriptional regulator, LacI family; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: yps:YPTB3798 gluconate utilization system Gnt-I transcriptional repressor.


ensembl_gene_id: Spro_4653
symbol: Spro_4653
gene_biotype: protein_coding
description:
  PFAM: Pirin domain protein; Cupin 2 conserved barrel domain protein; KEGG: ypi:YpsIP31758_4023 YhhW family protein; Belongs to the pirin family.


ensembl_gene_id: Spro_4656
symbol: iolE
gene_biotype: protein_coding
description:
  Xylose isomerase domain protein TIM barrel; Catalyzes the dehydration of inosose (2-keto-myo-inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D-(3,5/4)- trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi-inositol). Belongs to the IolE/MocC family.


ensembl_gene_id: Spro_4658
symbol: iolG
gene_biotype: protein_coding
description:
  Inositol 2-dehydrogenase; Involved in the oxidation of myo-inositol (MI) to 2-keto-myo- inositol (2KMI or 2-inosose).


ensembl_gene_id: Spro_4659
symbol: Spro_4659
gene_biotype: protein_coding
description:
  PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: yen:YE4027 putative thiamine pyrophosphate-dependent protein; Belongs to the TPP enzyme family.


ensembl_gene_id: Spro_4661
symbol: Spro_4661
gene_biotype: protein_coding
description:
  Transcriptional regulator, RpiR family; PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); KEGG: yen:YE4029 hypothetical protein.


ensembl_gene_id: Spro_4663
symbol: Spro_4663
gene_biotype: protein_coding
description:
  TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase; KEGG: yen:YE4031 putative aldehyde dehydrogenase.


ensembl_gene_id: Spro_4664
symbol: Spro_4664
gene_biotype: protein_coding
description:
  KEGG: stm:STM4418 sugar transporter; TIGRFAM: sugar transporter; PFAM: General substrate transporter; major facilitator superfamily MFS_1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.


ensembl_gene_id: Spro_4666
symbol: Spro_4666
gene_biotype: protein_coding
description:
  PFAM: conserved hypothetical protein; KEGG: stm:STM0503 putative YbbM family transport protein, metal resistance protein.


ensembl_gene_id: Spro_4667
symbol: Spro_4667
gene_biotype: protein_coding
description:
  ABC transporter-related protein; PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: kpn:KPN_00468 putative ATP-binding component of a transport system.


ensembl_gene_id: Spro_4669
symbol: Spro_4669
gene_biotype: protein_coding
description:
  PFAM: peptidylprolyl isomerase FKBP-type; KEGG: ent:Ent638_0982 peptidylprolyl isomerase, FKBP-type.


ensembl_gene_id: Spro_4671
symbol: Spro_4671
gene_biotype: protein_coding
description:
  PFAM: Fimbrial protein; KEGG: yps:YPTB3364 putative mannose-resistant Proteus-like fimbrial protein.


ensembl_gene_id: Spro_4673
symbol: Spro_4673
gene_biotype: protein_coding
description:
  PFAM: fimbrial biogenesis outer membrane usher protein; KEGG: aha:AHA_0521 outer membrane usher protein.


ensembl_gene_id: Spro_4679
symbol: Spro_4679
gene_biotype: protein_coding
description:
  Transcriptional regulator, LuxR family; PFAM: regulatory protein LuxR; KEGG: stt:t2311 fimbriae w protein.


ensembl_gene_id: Spro_4681
symbol: Spro_4681
gene_biotype: protein_coding
description:
  PFAM: regulatory protein AsnC/Lrp family; Helix-turn-helix type 11 domain protein; KEGG: aci:ACIAD1283 putative transcription regulator (AsnC family).


ensembl_gene_id: Spro_4682
symbol: Spro_4682
gene_biotype: protein_coding
description:
  PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: fjo:Fjoh_3994 short-chain dehydrogenase/reductase SDR.


ensembl_gene_id: Spro_4684
symbol: Spro_4684
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: mms:mma_2322 transcriptional regulator, LysR family.


ensembl_gene_id: Spro_4685
symbol: Spro_4685
gene_biotype: protein_coding
description:
  PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; KEGG: tte:TTE2131 NADH:flavin oxidoreductase, Old Yellow enzyme family.


ensembl_gene_id: Spro_4688
symbol: Spro_4688
gene_biotype: protein_coding
description:
  HI0933 family protein; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; HI0933 family protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: ypn:YPN_3615 hypothetical protein.


ensembl_gene_id: Spro_4692
symbol: Spro_4692
gene_biotype: protein_coding
description:
  Glutamate dehydrogenase (NADP(+)); PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; KEGG: yen:YE4051 NADP-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.


ensembl_gene_id: Spro_4693
symbol: Spro_4693
gene_biotype: protein_coding
description:
  KEGG: ypi:YpsIP31758_0364 carbohydrate uptake (CUT2 family) ABC transporter, periplasmic carbohydrate-binding protein.


ensembl_gene_id: Spro_4694
symbol: Spro_4694
gene_biotype: protein_coding
description:
  ABC transporter-related protein; PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ypi:YpsIP31758_0365 carbohydrate uptake (CUT2 family) ABC transporter, ATP-binding protein.


ensembl_gene_id: Spro_4695
symbol: Spro_4695
gene_biotype: protein_coding
description:
  Monosaccharide-transporting ATPase; PFAM: inner-membrane translocator; KEGG: ypi:YpsIP31758_0366 carbohydrate uptake (CUT2 family) ABC transporter, permease protein; Belongs to the binding-protein-dependent transport system permease family.


