# geneInfo

ensembl_gene_id: XNC1_0001
symbol: dnaA
gene_biotype: protein_coding
description:
  DNA replication initiator protein, transcriptional regulator of replication and housekeeping genes; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.


ensembl_gene_id: XNC1_0002
symbol: dnaN
gene_biotype: protein_coding
description:
  DNA polymerase III, beta-subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]


ensembl_gene_id: XNC1_0003
symbol: recF
gene_biotype: protein_coding
description:
  DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family.


ensembl_gene_id: XNC1_0004
symbol: gyrB
gene_biotype: protein_coding
description:
  DNA gyrase, subunit B (type II topoisomerase); A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP [...]


ensembl_gene_id: XNC1_0007
symbol: asd
gene_biotype: protein_coding
description:
  Aspartate-semialdehyde dehydrogenase, NAD(P)-binding; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.


ensembl_gene_id: XNC1_0014
symbol: XNC1_0014
gene_biotype: protein_coding
description:
  Putative Drug resistance transporter(fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.


ensembl_gene_id: XNC1_0018
symbol: hsdR
gene_biotype: protein_coding
description:
  Type I site-specific deoxyribonuclease HsdR; Subunit R is required for both nuclease and ATPase activities, but not for modification.


ensembl_gene_id: XNC1_0022
symbol: glmS
gene_biotype: protein_coding
description:
  L-glutamine:D-fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.


ensembl_gene_id: XNC1_0023
symbol: glmU
gene_biotype: protein_coding
description:
  Bifunctional: N-acetyl glucosamine-1-phosphate uridyltransferase (N-terminal); Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.


ensembl_gene_id: XNC1_0024
symbol: atpC
gene_biotype: protein_coding
description:
  Membrane-bound ATP synthase, F1 sector, epsilon-subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane.


ensembl_gene_id: XNC1_0025
symbol: atpD
gene_biotype: protein_coding
description:
  Membrane-bound ATP synthase, F1 sector, beta-subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family.


ensembl_gene_id: XNC1_0026
symbol: atpG
gene_biotype: protein_coding
description:
  Membrane-bound ATP synthase, F1 sector, gamma-subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.


ensembl_gene_id: XNC1_0027
symbol: atpA
gene_biotype: protein_coding
description:
  Membrane-bound ATP synthase, F1 sector, alpha-subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family.


ensembl_gene_id: XNC1_0028
symbol: atpH
gene_biotype: protein_coding
description:
  Membrane-bound ATP synthase, F1 sector, delta-subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family.


ensembl_gene_id: XNC1_0029
symbol: atpF
gene_biotype: protein_coding
description:
  Membrane-bound ATP synthase, F0 sector, subunit b; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family.


ensembl_gene_id: XNC1_0030
symbol: atpE
gene_biotype: protein_coding
description:
  Membrane-bound ATP synthase, F0 sector, subunit c; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.


ensembl_gene_id: XNC1_0031
symbol: atpB
gene_biotype: protein_coding
description:
  Membrane-bound ATP synthase, F0 sector, subunit a, important for FO assembly; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.


ensembl_gene_id: XNC1_0033
symbol: gidB
gene_biotype: protein_coding
description:
  Ribosomal RNA small subunit methyltransferase G; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.


ensembl_gene_id: XNC1_0034
symbol: gidA
gene_biotype: protein_coding
description:
  Glucose-inhibited division protein, oxidoreductase-like with FAD/NAD(P)-binding domain; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family.


ensembl_gene_id: XNC1_0035
symbol: mioC
gene_biotype: protein_coding
description:
  FMN-binding protein, required for biotin synthase activity; Function of homologous gene experimentally demonstrated in an other organism; factor.


ensembl_gene_id: XNC1_0036
symbol: asnC
gene_biotype: protein_coding
description:
  Transcriptional regulator of asparagine biosynthesis (AsnC family); Function of homologous gene experimentally demonstrated in an other organism; regulator.


ensembl_gene_id: XNC1_0037
symbol: asnA
gene_biotype: protein_coding
description:
  Asparagine synthetase A; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: XNC1_0039
symbol: yieN
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Homologs of previously reported genes of unknown function; putative regulator.


ensembl_gene_id: XNC1_0042
symbol: rbsK
gene_biotype: protein_coding
description:
  D-ribose transport protein (ABC superfamily, peri_bind) (C-terminal fragment); Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.


ensembl_gene_id: XNC1_0043
symbol: rbsR
gene_biotype: protein_coding
description:
  Transcriptional repressor for ribose metabolism (GalR/LacI family); Function of homologous gene experimentally demonstrated in an other organism; regulator.


ensembl_gene_id: XNC1_0044
symbol: hsrA
gene_biotype: protein_coding
description:
  Putative permease of the major facilitator superfamily; Function of strongly homologous gene; putative transporter; Belongs to the major facilitator superfamily.


ensembl_gene_id: XNC1_0050
symbol: yjcG
gene_biotype: protein_coding
description:
  Putative transporter of the sodium symport superfamily (SSS family); Transports acetate; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: XNC1_0052
symbol: acs
gene_biotype: protein_coding
description:
  acetyl-CoA synthetase, has propionyl-CoA synthetase activity; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. Enables the cell to use acetate during aerobic growth to generate energy via the TCA cycle, and biosynthetic compo [...]


ensembl_gene_id: XNC1_0053
symbol: sodA
gene_biotype: protein_coding
description:
  Superoxide dismutase, manganese; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.


ensembl_gene_id: XNC1_0056
symbol: trpS
gene_biotype: protein_coding
description:
  Tryptophan tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: XNC1_0057
symbol: gph
gene_biotype: protein_coding
description:
  Phosphoglycolate phosphatase, contains a phosphatase-like domain; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.


ensembl_gene_id: XNC1_0061
symbol: aroB
gene_biotype: protein_coding
description:
  Dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).


ensembl_gene_id: XNC1_0062
symbol: aroK
gene_biotype: protein_coding
description:
  Shikimate kinase I; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.


ensembl_gene_id: XNC1_0068
symbol: mrcA
gene_biotype: protein_coding
description:
  Bifunctional penicillin-binding protein 1a: transglycosylase (N-terminal); transpeptidase (C-terminal).


ensembl_gene_id: XNC1_0069
symbol: XNC1_0069
gene_biotype: protein_coding
description:
  Putative transposase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: XNC1_0077
symbol: XNC1_0077
gene_biotype: protein_coding
description:
  Putative transferase enzyme; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: XNC1_0078
symbol: fdhD
gene_biotype: protein_coding
description:
  Formate dehydrogenase formation protein; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.


ensembl_gene_id: XNC1_0091
symbol: XNC1_0091
gene_biotype: protein_coding
description:
  Cytosine/purines, uracil, thiamine, allantoin permease family protein (modular protein); Belongs to the purine-cytosine permease (2.A.39) family.


ensembl_gene_id: XNC1_0100
symbol: pfkA
gene_biotype: protein_coding
description:
  6-phosphofructokinase I; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.


ensembl_gene_id: XNC1_0101
symbol: yiiP
gene_biotype: protein_coding
description:
  Putative transport protein (CDF family); Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.


ensembl_gene_id: XNC1_0108
symbol: cpxP
gene_biotype: protein_coding
description:
  Periplasmic protein; Function experimentally demonstrated in the studied strain; putative regulator.


ensembl_gene_id: XNC1_0109
symbol: cpxR
gene_biotype: protein_coding
description:
  Two-component system, OmpR family, response regulator CpxR; Function experimentally demonstrated in the studied strain; regulator.


ensembl_gene_id: XNC1_0110
symbol: cpxA
gene_biotype: protein_coding
description:
  Two-component system, OmpR family, sensor histidine kinase CpxA; Function experimentally demonstrated in the studied strain; regulator.


ensembl_gene_id: XNC1_0111
symbol: XNC1_0111
gene_biotype: protein_coding
description:
  UDP-glucose/GDP-mannose dehydrogenase; Function of strongly homologous gene; enzyme; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.


ensembl_gene_id: XNC1_0114
symbol: XNC1_0114
gene_biotype: protein_coding
description:
  Aminotransferase; Function of strongly homologous gene; enzyme; Belongs to the DegT/DnrJ/EryC1 family.


ensembl_gene_id: XNC1_0116
symbol: rffE
gene_biotype: protein_coding
description:
  UDP-N-acetyl glucosamine-2-epimerase; Function of strongly homologous gene; enzyme; Belongs to the UDP-N-acetylglucosamine 2-epimerase family.


ensembl_gene_id: XNC1_0117
symbol: XNC1_0117
gene_biotype: protein_coding
description:
  Putative Glycosyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: XNC1_0134
symbol: XNC1_0134
gene_biotype: protein_coding
description:
  Putative glycosyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: XNC1_0139
symbol: yibK
gene_biotype: protein_coding
description:
  Putative tRNA/rRNA methyltransferase; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.


ensembl_gene_id: XNC1_0141
symbol: gpsA
gene_biotype: protein_coding
description:
  Glycerol-3-phosphate dehydrogenase (NAD+); Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.


ensembl_gene_id: XNC1_0142
symbol: secB
gene_biotype: protein_coding
description:
  Molecular chaperone in protein export, enhances activity of SecA (General Secretory Pathway); One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.


ensembl_gene_id: XNC1_0148
symbol: tdh
gene_biotype: protein_coding
description:
  Threonine 3-dehydrogenase, NAD(P)-binding; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family.


ensembl_gene_id: XNC1_0149
symbol: kbl
gene_biotype: protein_coding
description:
  2-amino-3-ketobutyrate CoA ligase (glycine acetyltransferase); Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.


ensembl_gene_id: XNC1_0150
symbol: rfaD
gene_biotype: protein_coding
description:
  ADP-L-glycero-D-mannoheptose-6-epimerase, NAD(P)-binding; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.


ensembl_gene_id: XNC1_0162
symbol: waaA
gene_biotype: protein_coding
description:
  3-deoxy-D-manno-octulosonic-acid transferase (KDO transferase); Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.


ensembl_gene_id: XNC1_0164
symbol: coaD
gene_biotype: protein_coding
description:
  CMP-deoxy-D-manno-octulosonate-lipid A transferase (phosphopantetheine adenylyltransferase); Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.


ensembl_gene_id: XNC1_0165
symbol: mutM
gene_biotype: protein_coding
description:
  Formamidopyrimidine DNA glycosylase, also acts on 5-formyluracil and 5-hydroxymethyluracil; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.


ensembl_gene_id: XNC1_0176
symbol: yicR
gene_biotype: protein_coding
description:
  Putative associated with replication fork, DNA repair protein; Belongs to the UPF0758 family. YicR subfamily.


ensembl_gene_id: XNC1_0177
symbol: dfp
gene_biotype: protein_coding
description:
  Bifunctional: 4'-phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.


ensembl_gene_id: XNC1_0178
symbol: dut
gene_biotype: protein_coding
description:
  Deoxyuridinetriphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.


ensembl_gene_id: XNC1_0179
symbol: ttk
gene_biotype: protein_coding
description:
  Nucleoid occlusion factor SlmA; Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.


ensembl_gene_id: XNC1_0180
symbol: pyrE
gene_biotype: protein_coding
description:
  Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).


ensembl_gene_id: XNC1_0181
symbol: rph
gene_biotype: protein_coding
description:
  RNase PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.


ensembl_gene_id: XNC1_0191
symbol: XNC1_0191
gene_biotype: protein_coding
description:
  Putative prophage primase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: XNC1_0208
symbol: tpiA
gene_biotype: protein_coding
description:
  Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.


ensembl_gene_id: XNC1_0213
symbol: glpK
gene_biotype: protein_coding
description:
  Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate.


ensembl_gene_id: XNC1_0216
symbol: zapB
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA.


ensembl_gene_id: XNC1_0217
symbol: menG
gene_biotype: protein_coding
description:
  Putative methyltransferase protein in menaquinone biosynthesis; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome.


ensembl_gene_id: XNC1_0218
symbol: menA
gene_biotype: protein_coding
description:
  1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily.


ensembl_gene_id: XNC1_0219
symbol: hslU
gene_biotype: protein_coding
description:
  ATPase component of the HslUV protease, also functions as molecular chaperone; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.


ensembl_gene_id: XNC1_0220
symbol: hslV
gene_biotype: protein_coding
description:
  Peptidase component of the HslUV protease; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.


ensembl_gene_id: XNC1_0221
symbol: ftsN
gene_biotype: protein_coding
description:
  Essential cell division protein, epimerase-or mutase-like; Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases.


ensembl_gene_id: XNC1_0223
symbol: priA
gene_biotype: protein_coding
description:
  Primosomal protein N' (factor Y) directs replication fork assembly at D-loops, ATP-dependent; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.


ensembl_gene_id: XNC1_0225
symbol: metJ
gene_biotype: protein_coding
description:
  Transcriptional repressor for methionine biosynthesis (MetJ family); This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family.


ensembl_gene_id: XNC1_0228
symbol: metL
gene_biotype: protein_coding
description:
  Bifunctional: aspartokinase II (N-terminal); homoserine dehydrogenase II (C-terminal), methionine sensitive.


ensembl_gene_id: XNC1_0229
symbol: ppc
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family.


ensembl_gene_id: XNC1_0242
symbol: XNC1_0242
gene_biotype: protein_coding
description:
  Putative Short-chain dehydrogenase/reductase SDR; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: XNC1_0247
symbol: XNC1_0247
gene_biotype: protein_coding
description:
  Putative Aminoacyl-tRNA synthetase, class Ia:Cupin region; Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: XNC1_0264
symbol: metF
gene_biotype: protein_coding
description:
  5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.


ensembl_gene_id: XNC1_0268
symbol: argC
gene_biotype: protein_coding
description:
  N-acetyl-gamma-glutamylphosphate reductase, NAD(P)-binding; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.


ensembl_gene_id: XNC1_0270
symbol: argG
gene_biotype: protein_coding
description:
  Argininosuccinate synthase (Citrulline--aspartate ligase); Belongs to the argininosuccinate synthase family. Type 1 subfamily.


ensembl_gene_id: XNC1_0272
symbol: oxyR
gene_biotype: protein_coding
description:
  Transcriptional regulator of oxidative stress, regulates intracellular hydrogen peroxide (LysR family); Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: XNC1_0273
symbol: sthA
gene_biotype: protein_coding
description:
  Soluble pyridine nucleotide transhydrogenase; Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.


ensembl_gene_id: XNC1_0277
symbol: trmA
gene_biotype: protein_coding
description:
  tRNA (uracil-5-)-methyltransferase; Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).


ensembl_gene_id: XNC1_0278
symbol: btuB
gene_biotype: protein_coding
description:
  Outer membrane porin: vitamin B12/cobalamin transport, receptor for E colicins, bacteriophage BF23; Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans- periplasmic membrane protein TonB; Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily.


ensembl_gene_id: XNC1_0288
symbol: birA
gene_biotype: protein_coding
description:
  Bifunctional: biotin-[acetylCoA carboxylase] holoenzyme synthetase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.


ensembl_gene_id: XNC1_0297
symbol: tufB
gene_biotype: protein_coding
description:
  Putative protein chain elongation factor EF-Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.


ensembl_gene_id: XNC1_0298
symbol: XNC1_0298
gene_biotype: protein_coding
description:
  Putative Retron-type reverse transcriptase-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: XNC1_0315
symbol: bfr
gene_biotype: protein_coding
description:
  Bacterioferritin, an iron storage homoprotein; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family.


ensembl_gene_id: XNC1_0316
symbol: rpsJ
gene_biotype: protein_coding
description:
  30S ribosomal subunit protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.


ensembl_gene_id: XNC1_0317
symbol: rplC
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.


ensembl_gene_id: XNC1_0318
symbol: rplD
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L4, regulates expression of S10 operon; Forms part of the polypeptide exit tunnel.


ensembl_gene_id: XNC1_0319
symbol: rplW
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.


ensembl_gene_id: XNC1_0320
symbol: rplB
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.


ensembl_gene_id: XNC1_0321
symbol: rpsS
gene_biotype: protein_coding
description:
  30S ribosomal subunit protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.


ensembl_gene_id: XNC1_0322
symbol: rplV
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.


ensembl_gene_id: XNC1_0323
symbol: rpsC
gene_biotype: protein_coding
description:
  30S ribosomal subunit protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.


ensembl_gene_id: XNC1_0325
symbol: rplP
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.


ensembl_gene_id: XNC1_0327
symbol: rpsQ
gene_biotype: protein_coding
description:
  30S ribosomal subunit protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.


ensembl_gene_id: XNC1_0328
symbol: rplN
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.


ensembl_gene_id: XNC1_0329
symbol: rplX
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.


ensembl_gene_id: XNC1_0330
symbol: rplE
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.


ensembl_gene_id: XNC1_0331
symbol: rpsN
gene_biotype: protein_coding
description:
  30S ribosomal subunit protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family.


ensembl_gene_id: XNC1_0332
symbol: rpsH
gene_biotype: protein_coding
description:
  30S ribosomal subunit protein S8, and regulator; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.


ensembl_gene_id: XNC1_0333
symbol: rplF
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.


ensembl_gene_id: XNC1_0334
symbol: rplR
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.


ensembl_gene_id: XNC1_0335
symbol: rpsE
gene_biotype: protein_coding
description:
  30S ribosomal subunit protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.


ensembl_gene_id: XNC1_0337
symbol: rplO
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.


ensembl_gene_id: XNC1_0338
symbol: secY
gene_biotype: protein_coding
description:
  Protein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.


ensembl_gene_id: XNC1_0340
symbol: rpsM
gene_biotype: protein_coding
description:
  30S ribosomal subunit protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family.


ensembl_gene_id: XNC1_0341
symbol: rpsK
gene_biotype: protein_coding
description:
  30S ribosomal subunit protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.


ensembl_gene_id: XNC1_0342
symbol: rpsD
gene_biotype: protein_coding
description:
  30S ribosomal subunit protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.


ensembl_gene_id: XNC1_0343
symbol: rpoA
gene_biotype: protein_coding
description:
  RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: XNC1_0348
symbol: rsmB
gene_biotype: protein_coding
description:
  16S rRNA m5C967 methyltransferase, S-adenosyl-L-methionine-dependent; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.


ensembl_gene_id: XNC1_0349
symbol: fmt
gene_biotype: protein_coding
description:
  10-formyltetrahydrofolate:L-methionyl-tRNA(fMet) N-formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.


ensembl_gene_id: XNC1_0350
symbol: def
gene_biotype: protein_coding
description:
  Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.


ensembl_gene_id: XNC1_0353
symbol: yrdC
gene_biotype: protein_coding
description:
  Putative RNA-binding protein with unique protein fold, with YrdC/RibB domain; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.


ensembl_gene_id: XNC1_0354
symbol: aroE
gene_biotype: protein_coding
description:
  Dehydroshikimate reductase, NAD(P)-binding; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).


ensembl_gene_id: XNC1_0364
symbol: hdfR
gene_biotype: protein_coding
description:
  HTH-type transcriptional regulator hdfR (H-NS-depdendent flhDC regulator); Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon.


ensembl_gene_id: XNC1_0366
symbol: yifB
gene_biotype: protein_coding
description:
  Putative enzyme (N-terminal); transcriptional regulator with P-loop containing NTP hydrolase domain (C-terminal).


ensembl_gene_id: XNC1_0368
symbol: XNC1_0368
gene_biotype: protein_coding
description:
  Acetolactate synthase isozyme II large subunit (AHAS-II) (Acetohydroxy-acid synthase II large subunit) (ALS-II).


ensembl_gene_id: XNC1_0370
symbol: ilvE
gene_biotype: protein_coding
description:
  Branched-chain amino-acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: XNC1_0372
symbol: ilvA
gene_biotype: protein_coding
description:
  Threonine deaminase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.


ensembl_gene_id: XNC1_0376
symbol: ilvC
gene_biotype: protein_coding
description:
  Ketol-acid reductoisomerase, NAD(P)-binding; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.


ensembl_gene_id: XNC1_0378
symbol: rep
gene_biotype: protein_coding
description:
  Rep helicase, a single-stranded DNA-dependent ATPase; Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.


ensembl_gene_id: XNC1_0379
symbol: gpp
gene_biotype: protein_coding
description:
  Guanosine pentaphosphatase, also has exopolyphosphatase activity; Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities.


ensembl_gene_id: XNC1_0380
symbol: rhlB
gene_biotype: protein_coding
description:
  Putative ATP-dependent helicase with nucleoside triP hydrolase domain; DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. Belongs to the DEAD box helicase family. RhlB subfamily.


ensembl_gene_id: XNC1_0383
symbol: rho
gene_biotype: protein_coding
description:
  Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.


ensembl_gene_id: XNC1_0384
symbol: rfe
gene_biotype: protein_coding
description:
  UDP-GlcNAc:undecaprenylphosphate GlcNAc-1-phosphate transferase; Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP-C55).


ensembl_gene_id: XNC1_0385
symbol: wzzE
gene_biotype: protein_coding
description:
  Modulator of enterobacterial common antigen (ECA) polysaccharide chain length; Modulates the polysaccharide chain length of enterobacterial common antigen (ECA); Belongs to the WzzB/Cld/Rol family.


ensembl_gene_id: XNC1_0386
symbol: rffE-2
gene_biotype: protein_coding
description:
  UDP-N-acetyl glucosamine-2-epimerase; Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP- N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues.


ensembl_gene_id: XNC1_0387
symbol: rffD
gene_biotype: protein_coding
description:
  UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase; Catalyzes the four-electron oxidation of UDP-N-acetyl-D- mannosamine (UDP-ManNAc), reducing NAD(+) and releasing UDP-N- acetylmannosaminuronic acid (UDP-ManNAcA); Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. WecC subfamily.


ensembl_gene_id: XNC1_0388
symbol: rffG
gene_biotype: protein_coding
description:
  dTDP-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.


ensembl_gene_id: XNC1_0389
symbol: rffH
gene_biotype: protein_coding
description:
  Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.


ensembl_gene_id: XNC1_0390
symbol: rffC
gene_biotype: protein_coding
description:
  Putative acyl-CoA N-acyltransferase, lipopolysaccharide biosynthesis protein; Catalyzes the acetylation of dTDP-fucosamine (dTDP-4-amino- 4,6-dideoxy-D-galactose) to dTDP-Fuc4NAc, which is utilized in the biosynthesis of the enterobacterial common antigen (ECA). Belongs to the WecD family.


ensembl_gene_id: XNC1_0391
symbol: rffA
gene_biotype: protein_coding
description:
  TDP-4-oxo-6-deoxy-D-glucose transaminase; Catalyzes the synthesis of dTDP-4-amino-4,6-dideoxy-D- galactose (dTDP-Fuc4N) from dTDP-4-keto-6-deoxy-D-glucose (dTDP-D- Glc4O) and L-glutamate; Belongs to the DegT/DnrJ/EryC1 family.


ensembl_gene_id: XNC1_0392
symbol: wzxE
gene_biotype: protein_coding
description:
  O-antigen translocase in LPS biosynthesis; Mediates the transbilayer movement of Und-PP-GlcNAc-ManNAcA- Fuc4NAc (lipid III) from the inner to the outer leaflet of the cytoplasmic membrane during the assembly of enterobacterial common antigen (ECA); Belongs to the polysaccharide transport (PST) (TC 2.A.66.2) family.


ensembl_gene_id: XNC1_0395
symbol: wzyE
gene_biotype: protein_coding
description:
  Putative ECA polymerization protein; Probably involved in the polymerization of enterobacterial common antigen (ECA) trisaccharide repeat units; Belongs to the WzyE family.


ensembl_gene_id: XNC1_0396
symbol: rffM
gene_biotype: protein_coding
description:
  Putative UDP-N-acetyl-D-mannosaminuronic acid transferase, with FMN-linked oxidoreductase domain; Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA (Lipid II), the second lipid-linked intermediate involved in enterobacterial common antigen (ECA) synthesis.


ensembl_gene_id: XNC1_0404
symbol: hemD
gene_biotype: protein_coding
description:
  Uroporphyrinogen III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.


ensembl_gene_id: XNC1_0405
symbol: hemC
gene_biotype: protein_coding
description:
  Hydroxymethylbilane synthase (porphobilinogen deaminase); Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.


ensembl_gene_id: XNC1_0407
symbol: cyaY
gene_biotype: protein_coding
description:
  Protein cyaY; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.


ensembl_gene_id: XNC1_0409
symbol: dapF
gene_biotype: protein_coding
description:
  Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.


ensembl_gene_id: XNC1_0411
symbol: xerC
gene_biotype: protein_coding
description:
  Site-specific tyrosine recombinase; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerD binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerC specifically ex [...]


ensembl_gene_id: XNC1_0415
symbol: corA
gene_biotype: protein_coding
description:
  Mg2+/Ni2+/Co2+ transport protein (Mg transport system I) (MIT family); Mediates influx of magnesium ions. Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.


ensembl_gene_id: XNC1_0433
symbol: psd
gene_biotype: protein_coding
description:
  Phosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).


ensembl_gene_id: XNC1_0434
symbol: yjeQ
gene_biotype: protein_coding
description:
  Putative enzyme with 2 nucleoside triP hydrolase domains; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.


ensembl_gene_id: XNC1_0435
symbol: orn
gene_biotype: protein_coding
description:
  Oligoribonuclease; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family.


ensembl_gene_id: XNC1_0441
symbol: XNC1_0441
gene_biotype: protein_coding
description:
  Putative transcriptional regulator (LysR family); Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: XNC1_0446
symbol: XNC1_0446
gene_biotype: protein_coding
description:
  Putative 4-hydroxyphenylacetate 3-monooxygenase, oxygenase component (4-HPA 3-monooxygenase large component) (4-HPA 3-hydroxylase).


ensembl_gene_id: XNC1_0450
symbol: queG
gene_biotype: protein_coding
description:
  Putative electron transport protein yjeS; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family.


ensembl_gene_id: XNC1_0453
symbol: mutL
gene_biotype: protein_coding
description:
  Enzyme in methyl-directed mismatch repair, stimulates binding of Vsr and MutS to heteroduplex DNA; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.


ensembl_gene_id: XNC1_0454
symbol: miaA
gene_biotype: protein_coding
description:
  Delta(2)-isopentenylpyrophosphate tRNA-adenosine transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.


ensembl_gene_id: XNC1_0455
symbol: hfq
gene_biotype: protein_coding
description:
  Host factor I for bacteriophage Q beta replication, plays a role in degradation of RNA transcripts; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.


ensembl_gene_id: XNC1_0456
symbol: hflX
gene_biotype: protein_coding
description:
  GTPase HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.


ensembl_gene_id: XNC1_0459
symbol: hflK
gene_biotype: protein_coding
description:
  With HflC, part of modulator for protease specific for FtsH phage lambda cII repressor; HflC and HflK could encode or regulate a protease.


ensembl_gene_id: XNC1_0460
symbol: hflC
gene_biotype: protein_coding
description:
  With HflK, part of modulator for protease specific for FtsH phage lambda cII repressor; HflC and HflK could regulate a protease.


ensembl_gene_id: XNC1_0461
symbol: purA
gene_biotype: protein_coding
description:
  Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.


ensembl_gene_id: XNC1_0463
symbol: rnr
gene_biotype: protein_coding
description:
  RNase R, 3'-5' exoribonuclease; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. Belongs to the RNR ribonuclease family. RNase R subfamily.


ensembl_gene_id: XNC1_0464
symbol: rlmB
gene_biotype: protein_coding
description:
  Putative tRNA/rRNA methyltransferase; Specifically methylates the ribose of guanosine 2251 in 23S rRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.


ensembl_gene_id: XNC1_0466
symbol: priB
gene_biotype: protein_coding
description:
  Primosomal replication protein N; Binds single-stranded DNA at the primosome assembly site (PAS); Belongs to the PriB family.


ensembl_gene_id: XNC1_0467
symbol: rpsR
gene_biotype: protein_coding
description:
  30S ribosomal subunit protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.


ensembl_gene_id: XNC1_0473
symbol: cysQ
gene_biotype: protein_coding
description:
  Protein that acts on 3'-phosphoadenosine-5'-phosphosulfate with sugar phosphatase domain; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family.


ensembl_gene_id: XNC1_0477
symbol: msrA
gene_biotype: protein_coding
description:
  Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.


ensembl_gene_id: XNC1_0481
symbol: ppa
gene_biotype: protein_coding
description:
  Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.


ensembl_gene_id: XNC1_0483
symbol: mpl
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily.


ensembl_gene_id: XNC1_0484
symbol: argR
gene_biotype: protein_coding
description:
  Transcriptional repressor of arginine synthesis (ArgR familiy); Regulates arginine biosynthesis genes.


ensembl_gene_id: XNC1_0490
symbol: rplU
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.


ensembl_gene_id: XNC1_0493
symbol: obgE
gene_biotype: protein_coding
description:
  Putative GTP-binding protein with nucleoside triP hydrolase domain; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.


ensembl_gene_id: XNC1_0495
symbol: greA
gene_biotype: protein_coding
description:
  Transcription elongation factor, cleaves 3' nucleotide of paused mRNA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.


ensembl_gene_id: XNC1_0497
symbol: ftsJ
gene_biotype: protein_coding
description:
  23 S rRNA methyltransferase; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.


ensembl_gene_id: XNC1_0498
symbol: ftsH
gene_biotype: protein_coding
description:
  ATP-dependent zinc-metallo protease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family.  In the central section; belongs to the AAA ATPase family.


ensembl_gene_id: XNC1_0499
symbol: folP
gene_biotype: protein_coding
description:
  7,8-dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.


ensembl_gene_id: XNC1_0500
symbol: glmM
gene_biotype: protein_coding
description:
  Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.


ensembl_gene_id: XNC1_0501
symbol: secG
gene_biotype: protein_coding
description:
  Protein-export membrane protein SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.


ensembl_gene_id: XNC1_0503
symbol: rimP
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.


ensembl_gene_id: XNC1_0505
symbol: infB
gene_biotype: protein_coding
description:
  Protein chain initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.


ensembl_gene_id: XNC1_0506
symbol: rbfA
gene_biotype: protein_coding
description:
  Ribosome-binding factor, role in processing of 10S rRNA; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.


ensembl_gene_id: XNC1_0507
symbol: truB
gene_biotype: protein_coding
description:
  tRNA pseudouridine 5S synthase; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.


ensembl_gene_id: XNC1_0508
symbol: rpsO
gene_biotype: protein_coding
description:
  30S ribosomal subunit protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.


ensembl_gene_id: XNC1_0509
symbol: pnp
gene_biotype: protein_coding
description:
  Polynucleotide phosphorylase, has polyadenylase activity; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.


ensembl_gene_id: XNC1_0510
symbol: nlpI
gene_biotype: protein_coding
description:
  NlpI lipoprotein believed to be involved in cell division with transferase domain; May be involved in cell division.


ensembl_gene_id: XNC1_0511
symbol: deaD
gene_biotype: protein_coding
description:
  Cold-shock DeaD box ATP-dependent RNA helicase; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.


ensembl_gene_id: XNC1_0514
symbol: XNC1_0514
gene_biotype: protein_coding
description:
  Putative invasin; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.


ensembl_gene_id: XNC1_0520
symbol: nrdG
gene_biotype: protein_coding
description:
  Anaerobic ribonucleotide reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.


ensembl_gene_id: XNC1_0524
symbol: pyrI
gene_biotype: protein_coding
description:
  Aspartate carbamoyltransferase, regulatory subunit (allosteric regulation); Involved in allosteric regulation of aspartate carbamoyltransferase.


ensembl_gene_id: XNC1_0529
symbol: ydeP
gene_biotype: protein_coding
description:
  Putative formate dehydrogenase (C-terminal), related to acid resistance with formate dehydrogenase/DMSO reductase, domains 1-3 and ADC-like domain; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: XNC1_0535
symbol: pyrB
gene_biotype: protein_coding
description:
  Aspartate carbamoyltransferase, catalytic subunit; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.


ensembl_gene_id: XNC1_0551
symbol: argI
gene_biotype: protein_coding
description:
  Ornithine carbamoyltransferase 1; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.


ensembl_gene_id: XNC1_0553
symbol: rraB
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.


ensembl_gene_id: XNC1_0561
symbol: yeaT
gene_biotype: protein_coding
description:
  Putative transcriptional regulator with periplasmic binding protein domain (LysR family); Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: XNC1_0563
symbol: yeaV
gene_biotype: protein_coding
description:
  Putative betaine/choline/glycine transport protein (BCCT family); Belongs to the BCCT transporter (TC 2.A.15) family.


ensembl_gene_id: XNC1_0564
symbol: yeaW
gene_biotype: protein_coding
description:
  Putative di(mono)oxygenase, alpha subunit with ISP and Bet v1-like domains; Converts carnitine to trimethylamine and malic semialdehyde.


ensembl_gene_id: XNC1_0565
symbol: gabD
gene_biotype: protein_coding
description:
  Succinate-semialdehyde dehydrogenase I, NADP-dependent; Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: XNC1_0567
symbol: yeaX
gene_biotype: protein_coding
description:
  Carnitine monooxygenase reductase subunit; Converts carnitine to trimethylamine and malic semialdehyde.


ensembl_gene_id: XNC1_0570
symbol: fliY
gene_biotype: protein_coding
description:
  Cysteine transport protein (ABC superfamily, peri_bind); Belongs to the bacterial solute-binding protein 3 family.


ensembl_gene_id: XNC1_0574
symbol: XNC1_0574
gene_biotype: protein_coding
description:
  Putative cysteine transport protein (ABC superfamily, peri_bind); Belongs to the bacterial solute-binding protein 3 family.


ensembl_gene_id: XNC1_0582
symbol: thiG
gene_biotype: protein_coding
description:
  Thiamin biosynthesis enzyme subunit, with ThiH; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.


ensembl_gene_id: XNC1_0583
symbol: thiS
gene_biotype: protein_coding
description:
  C-terminally thiocarboxylated form is intermediate sulfur donor in thiazole formation; part of ThiF/ThiS complex; complexes with ThiG also.


ensembl_gene_id: XNC1_0585
symbol: thiE
gene_biotype: protein_coding
description:
  Thiamin phosphate synthase (thiamin phosphate pyrophosphorylase); Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.


ensembl_gene_id: XNC1_0586
symbol: thiC
gene_biotype: protein_coding
description:
  5'-phosphoryl-5-aminoimidazole = 4-amino-5-hydroxymethyl-2-methylpyrimidine-P; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.


ensembl_gene_id: XNC1_0618
symbol: hemE
gene_biotype: protein_coding
description:
  Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.


ensembl_gene_id: XNC1_0619
symbol: nfi
gene_biotype: protein_coding
description:
  Endonuclease V (deoxyinosine 3'endoduclease); DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.


ensembl_gene_id: XNC1_0621
symbol: hupA
gene_biotype: protein_coding
description:
  DNA-binding protein HU-alpha (HU-2), plays a role in DNA replication and in rpo translation; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.


ensembl_gene_id: XNC1_0624
symbol: purH
gene_biotype: protein_coding
description:
  Bifunctional: IMP cyclohydrolase (N-terminal); phosphoribosylaminoimidazolecarboxamide formyltransferase (C-terminal).


ensembl_gene_id: XNC1_0631
symbol: ybgL
gene_biotype: protein_coding
description:
  Putative lactam utilization protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.


ensembl_gene_id: XNC1_0635
symbol: frdD
gene_biotype: protein_coding
description:
  Fumarate reductase, anaerobic, membrane anchor polypeptide; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane.


ensembl_gene_id: XNC1_0637
symbol: frdB
gene_biotype: protein_coding
description:
  Fumarate reductase, anaerobic, Fe-S subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.


ensembl_gene_id: XNC1_0642
symbol: poxA
gene_biotype: protein_coding
description:
  Transposase (fragment); With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF- P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta-lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P; Belongs to the class-II aminoacyl-tRNA synthetase family. EpmA subfamily.


ensembl_gene_id: XNC1_0655
symbol: yhhQ
gene_biotype: protein_coding
description:
  Putative integral membrane protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.


ensembl_gene_id: XNC1_0656
symbol: tusA
gene_biotype: protein_coding
description:
  Small ubiquitous RNA-binding protein required for normal growth, cytoplasmic (modular protein); Sulfur carrier protein involved in sulfur trafficking in the cell. Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA. Interacts with IscS and stimulates its cysteine desulfurase activity. Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation. Also appears to be inv [...]


ensembl_gene_id: XNC1_0661
symbol: yhhF
gene_biotype: protein_coding
description:
  Putative methyltransferase with SAM-dependent methyltransferase domain; Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle; Belongs to the methyltransferase superfamily. RsmD family.


ensembl_gene_id: XNC1_0662
symbol: ftsY
gene_biotype: protein_coding
description:
  Cell division protein: membrane binding (N-terminal); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.


ensembl_gene_id: XNC1_0663
symbol: ftsE
gene_biotype: protein_coding
description:
  Putative transport protein (ABC superfamily, atp_bind); Part of the ABC transporter FtsEX involved in cellular division.


ensembl_gene_id: XNC1_0664
symbol: ftsX
gene_biotype: protein_coding
description:
  Integral membrane cell division protein; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.


ensembl_gene_id: XNC1_0665
symbol: rpoH
gene_biotype: protein_coding
description:
  Sigma H (sigma 32) factor of RNA polymerase; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.


ensembl_gene_id: XNC1_0671
symbol: livH
gene_biotype: protein_coding
description:
  High-affinity branched-chain amino acid transport protein (ABC superfamily, membrane); Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: XNC1_0674
symbol: livF
gene_biotype: protein_coding
description:
  High-affinity branched-chain amino acid transport protein (ABC superfamily, atp_bind); Belongs to the ABC transporter superfamily.


ensembl_gene_id: XNC1_0685
symbol: trpR
gene_biotype: protein_coding
description:
  Transcriptional repressor for tryptophan biosynthesis (TrpR family); This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region.


ensembl_gene_id: XNC1_0686
symbol: XNC1_0686
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.


ensembl_gene_id: XNC1_0688
symbol: rob
gene_biotype: protein_coding
description:
  Transcriptional activator for resistance to antibiotics, organic solvents and heavy metals (AraC/XylS family) (right origin-binding protein).


ensembl_gene_id: XNC1_0691
symbol: arcA
gene_biotype: protein_coding
description:
  Two-component system, OmpR family, aerobic respiration control protein ArcA; Response regulator in two-component regulatory system with ArcB (or CpxA), regulates respiratory and fermentative metabolism (OmpR family).


ensembl_gene_id: XNC1_0692
symbol: thrA
gene_biotype: protein_coding
description:
  Bifunctional: aspartokinase I (N-terminal); homoserine dehydrogenase I (C-terminal), threonine sensitive.


ensembl_gene_id: XNC1_0693
symbol: thrB
gene_biotype: protein_coding
description:
  Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.


ensembl_gene_id: XNC1_0703
symbol: talB
gene_biotype: protein_coding
description:
  Transaldolase B; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.


ensembl_gene_id: XNC1_0708
symbol: dnaK
gene_biotype: protein_coding
description:
  Chaperone Hsp70 in DNA biosynthesis/cell division; Acts as a chaperone; Belongs to the heat shock protein 70 family.


ensembl_gene_id: XNC1_0710
symbol: dnaJ
gene_biotype: protein_coding
description:
  Heat shock protein (Hsp40), co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent  [...]


ensembl_gene_id: XNC1_0743
symbol: oppA3
gene_biotype: protein_coding
description:
  OppA-like, oligopeptide transport protein (ABC superfamily, peri_bind); Function of homologous gene experimentally demonstrated in an other organism; transporter.


ensembl_gene_id: XNC1_0744
symbol: oppA4
gene_biotype: protein_coding
description:
  Oligopeptide transport protein (ABC superfamily, peri_bind); Function of homologous gene experimentally demonstrated in an other organism; transporter.


ensembl_gene_id: XNC1_0747
symbol: sbcD
gene_biotype: protein_coding
description:
  ATP-dependent dsDNA exonuclease; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.


ensembl_gene_id: XNC1_0748
symbol: phoB
gene_biotype: protein_coding
description:
  Two-component system, OmpR family, phosphate regulon response regulator PhoB; Response regulator in two-component regulatory system with PhoR (or CreC), regulation of Pi uptake (OmpR family).


ensembl_gene_id: XNC1_0749
symbol: phoR
gene_biotype: protein_coding
description:
  Two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR; Sensory histidine kinase in two-component regulatory system with PhoB, regulation of Pi uptake, senses Pi.


ensembl_gene_id: XNC1_0751
symbol: brnQ
gene_biotype: protein_coding
description:
  Branched-chain amino acid transport system II (LIV-II) (LIVCS family); Component of the transport system for branched-chain amino acids.


ensembl_gene_id: XNC1_0759
symbol: tgt
gene_biotype: protein_coding
description:
  S-adenosylmethionine:tRNA (m6t6A37) ribosyltransferase-isomerase (fragment); Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophil [...]


ensembl_gene_id: XNC1_0760
symbol: yajC
gene_biotype: protein_coding
description:
  Preprotein translocase, auxillary membrane component (General Secretory Pathway); The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.


ensembl_gene_id: XNC1_0761
symbol: secD
gene_biotype: protein_coding
description:
  Preprotein translocase, auxillary membrane component (General Secretory Pathway); Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.


ensembl_gene_id: XNC1_0763
symbol: nrdR
gene_biotype: protein_coding
description:
  Putative transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.


ensembl_gene_id: XNC1_0764
symbol: ribD
gene_biotype: protein_coding
description:
  Bifunctional: diaminohydroxyphosphoribosylaminopyrimidine deaminase (N-terminal); Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.


ensembl_gene_id: XNC1_0765
symbol: ribE
gene_biotype: protein_coding
description:
  Riboflavin synthase, beta chain; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family.


ensembl_gene_id: XNC1_0766
symbol: nusB
gene_biotype: protein_coding
description:
  Transcription termination; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.


ensembl_gene_id: XNC1_0767
symbol: thiL
gene_biotype: protein_coding
description:
  Thiamin-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.


ensembl_gene_id: XNC1_0768
symbol: pgpA
gene_biotype: protein_coding
description:
  Phosphatidylglycerophosphatase A; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).


ensembl_gene_id: XNC1_0769
symbol: pcp
gene_biotype: protein_coding
description:
  Pyrrolidone-carboxylate peptidase; Removes 5-oxoproline from various penultimate amino acid residues except L-proline; Belongs to the peptidase C15 family.


ensembl_gene_id: XNC1_0772
symbol: XNC1_0772
gene_biotype: protein_coding
description:
  Putative transcriptional regulator LuxR family (partial); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.


ensembl_gene_id: XNC1_0773
symbol: XNC1_0773
gene_biotype: protein_coding
description:
  Putative transcriptional regulator (partial); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.


ensembl_gene_id: XNC1_0774
symbol: XNC1_0774
gene_biotype: protein_coding
description:
  Putative transcriptional regulator (LuxR family, partial); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.


ensembl_gene_id: XNC1_0787
symbol: XNC1_0787
gene_biotype: protein_coding
description:
  Putative Maf-like protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.


ensembl_gene_id: XNC1_0788
symbol: mreD
gene_biotype: protein_coding
description:
  Rod shape-determining protein; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins. Belongs to the MreD family.


ensembl_gene_id: XNC1_0793
symbol: aroQ
gene_biotype: protein_coding
description:
  3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.


ensembl_gene_id: XNC1_0794
symbol: accB
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase, biotin carboxyl carrier protein subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.


ensembl_gene_id: XNC1_0795
symbol: accC
gene_biotype: protein_coding
description:
  Acetyl CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.


ensembl_gene_id: XNC1_0797
symbol: panF
gene_biotype: protein_coding
description:
  Sodium:pantothenate symporter (SSS family); Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: XNC1_0798
symbol: prmA
gene_biotype: protein_coding
description:
  Methylation of 50S ribosomal subunit protein L11; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family.


ensembl_gene_id: XNC1_0799
symbol: dusB
gene_biotype: protein_coding
description:
  tRNA-dihydrouridine synthase B; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.


ensembl_gene_id: XNC1_0800
symbol: fis
gene_biotype: protein_coding
description:
  DNA-binding protein Fis; Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters; Belongs to the transcriptional regulatory Fis family.


ensembl_gene_id: XNC1_0811
symbol: XNC1_0811
gene_biotype: protein_coding
description:
  4-hydroxyphenylacetate 3-monooxygenase, oxygenase component (4-HPA 3-monooxygenase large component) (4-HPA 3-hydroxylase).


ensembl_gene_id: XNC1_0816
symbol: yfaU
gene_biotype: protein_coding
description:
  Putative 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, with PEP/pyruvate domain; Belongs to the HpcH/HpaI aldolase family.


ensembl_gene_id: XNC1_0819
symbol: XNC1_0819
gene_biotype: protein_coding
description:
  5-carboxymethyl-2-hydroxymuconate delta-isomerase (5-carboxymethyl-2-hydroxymuconic acid isomerase) (CHM isomerase) (CHMI).


ensembl_gene_id: XNC1_0829
symbol: XNC1_0829
gene_biotype: protein_coding
description:
  Putative DNA-binding prophage protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; extrachromosomal origin; Belongs to the 'phage' integrase family.


ensembl_gene_id: XNC1_0833
symbol: XNC1_0833
gene_biotype: protein_coding
description:
  Putative transposase (fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: XNC1_0852
symbol: XNC1_0852
gene_biotype: protein_coding
description:
  Major facilitator transporter (fragment); Gene remnant; transporter; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: XNC1_0869
symbol: XNC1_0869
gene_biotype: protein_coding
description:
  Putative Transposase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: XNC1_0874
symbol: dctA
gene_biotype: protein_coding
description:
  Citrate and C4-dicarboxylic acids transport protein (DAACS family); Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane. Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: XNC1_0875
symbol: aldB
gene_biotype: protein_coding
description:
  Aldehyde dehydrogenase B (lactaldehyde dehydrogenase); Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: XNC1_0878
symbol: eno
gene_biotype: protein_coding
description:
  Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.


ensembl_gene_id: XNC1_0879
symbol: pyrG
gene_biotype: protein_coding
description:
  CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.


ensembl_gene_id: XNC1_0882
symbol: relA
gene_biotype: protein_coding
description:
  (p)ppGpp synthetase I (GTP pyrophosphokinase); In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.


ensembl_gene_id: XNC1_0883
symbol: rumA
gene_biotype: protein_coding
description:
  23S rRNA m5U1939 methyltransferase; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.


ensembl_gene_id: XNC1_0885
symbol: dgt
gene_biotype: protein_coding
description:
  Deoxyguanosine triphosphate triphosphohydrolase; dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs; Belongs to the dGTPase family. Type 1 subfamily.


ensembl_gene_id: XNC1_0886
symbol: mtn
gene_biotype: protein_coding
description:
  5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulatio [...]


ensembl_gene_id: XNC1_0887
symbol: btuF
gene_biotype: protein_coding
description:
  Cyano-cobalamin transport protein (ABC superfamily, peri_bind); Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC.


ensembl_gene_id: XNC1_0892
symbol: mrcB
gene_biotype: protein_coding
description:
  Bifunctional penicillin-binding protein 1b: glycosyl transferase (N-terminal); Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).


ensembl_gene_id: XNC1_0895
symbol: dksA
gene_biotype: protein_coding
description:
  DnaK suppressor protein; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.


ensembl_gene_id: XNC1_0896
symbol: yadB
gene_biotype: protein_coding
description:
  Putative glutamyl t-RNA synthetase with nucleotidylyl transferase domain; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.


ensembl_gene_id: XNC1_0898
symbol: pcnB
gene_biotype: protein_coding
description:
  poly(A) polymerase I; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control. Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.


ensembl_gene_id: XNC1_0900
symbol: panB
gene_biotype: protein_coding
description:
  3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.


ensembl_gene_id: XNC1_0901
symbol: panC
gene_biotype: protein_coding
description:
  Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.


ensembl_gene_id: XNC1_0910
symbol: yadF
gene_biotype: protein_coding
description:
  Putative beta-carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family.


ensembl_gene_id: XNC1_0911
symbol: hpt
gene_biotype: protein_coding
description:
  Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.


ensembl_gene_id: XNC1_0920
symbol: ppiB
gene_biotype: protein_coding
description:
  Peptidyl-prolyl cis-trans isomerase B (rotamase B); PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.


ensembl_gene_id: XNC1_0921
symbol: lpxH
gene_biotype: protein_coding
description:
  UDP-2,3-diacylglucosamine hydrolase; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: XNC1_0922
symbol: purE
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazole carboxylase = AIR carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).


ensembl_gene_id: XNC1_0923
symbol: purK
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazole carboxylase = AIR carboxylase, CO(2)-fixing subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).


ensembl_gene_id: XNC1_0929
symbol: ybbO
gene_biotype: protein_coding
description:
  Putative oxidoreductase, NAD(P)-binding domain; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: XNC1_0944
symbol: ybaL
gene_biotype: protein_coding
description:
  Putative transport protein with NAD(P)-binding Rossmann-fold domain (CPA2 family); Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.


ensembl_gene_id: XNC1_0947
symbol: hemH
gene_biotype: protein_coding
description:
  Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.


ensembl_gene_id: XNC1_0949
symbol: adk
gene_biotype: protein_coding
description:
  Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.


ensembl_gene_id: XNC1_0951
symbol: recR
gene_biotype: protein_coding
description:
  Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.


ensembl_gene_id: XNC1_0952
symbol: XNC1_0952
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.


ensembl_gene_id: XNC1_0953
symbol: dnaX
gene_biotype: protein_coding
description:
  DNA polymerase III, tau and gamma subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.


ensembl_gene_id: XNC1_0954
symbol: apt
gene_biotype: protein_coding
description:
  Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.


ensembl_gene_id: XNC1_0969
symbol: glnK
gene_biotype: protein_coding
description:
  Regulatory protein (P-II 2) for nitrogen assimilation, regulates GlnL (NRII), GlnE (ATase), and AmtB (ammonium transporter); Belongs to the P(II) protein family.


ensembl_gene_id: XNC1_0970
symbol: mdlB
gene_biotype: protein_coding
description:
  ATP-binding cassette, subfamily B, multidrug efflux pump; Putative transport protein, multidrug resistance-like (ABC superfamily, membrane (N-terminal), atp_bind (C-terminal)).


ensembl_gene_id: XNC1_0974
symbol: ybaX
gene_biotype: protein_coding
description:
  Putative (aluminum) resistance protein with adenine nucleotide alpha hydrolase domain; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.


ensembl_gene_id: XNC1_0979
symbol: hupB
gene_biotype: protein_coding
description:
  DNA-binding protein HU-beta, NS1 (HU-1), plays a role in DNA replication and in rpo translation; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.


ensembl_gene_id: XNC1_0982
symbol: lon
gene_biotype: protein_coding
description:
  Transposase (fragment); ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.


ensembl_gene_id: XNC1_0983
symbol: clpX
gene_biotype: protein_coding
description:
  ATPase, chaperone subunit of serine protease; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.


ensembl_gene_id: XNC1_0984
symbol: clpP
gene_biotype: protein_coding
description:
  Proteolytic subunit of clpA-clpP ATP-dependent serine protease; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.


ensembl_gene_id: XNC1_0985
symbol: tig
gene_biotype: protein_coding
description:
  Peptidyl-prolyl cis/trans isomerase (trigger factor), molecular chaperone involved in cell division; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.


ensembl_gene_id: XNC1_0986
symbol: bolA
gene_biotype: protein_coding
description:
  Transcriptional activator of morphogenic pathway (BolA family), important in general stress response; Belongs to the BolA/IbaG family.


ensembl_gene_id: XNC1_0994
symbol: cyoE
gene_biotype: protein_coding
description:
  Protoheme IX farnesyltransferase (heme O biosynthesis); Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.


ensembl_gene_id: XNC1_0997
symbol: panE
gene_biotype: protein_coding
description:
  2-dehydropantoate reductase, NADPH-specific, alternative pyrimidine biosynthesis; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.


ensembl_gene_id: XNC1_0999
symbol: thiI
gene_biotype: protein_coding
description:
  Sulfur transfer protein (from cys to ThiS and from IscS to U8-tRNA); Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.


ensembl_gene_id: XNC1_1000
symbol: xseB
gene_biotype: protein_coding
description:
  Exonuclease VII, small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.


ensembl_gene_id: XNC1_1002
symbol: dxs
gene_biotype: protein_coding
description:
  1-deoxy-D-xylulose 5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.


ensembl_gene_id: XNC1_1015
symbol: XNC1_1015
gene_biotype: protein_coding
description:
  Putative phage integrase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: XNC1_1024
symbol: metK
gene_biotype: protein_coding
description:
  Protein SprT (fragment); Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.


ensembl_gene_id: XNC1_1025
symbol: speA
gene_biotype: protein_coding
description:
  Arginine decarboxylase, PLP-binding, biosynthetic; Catalyzes the biosynthesis of agmatine from arginine.


ensembl_gene_id: XNC1_1027
symbol: speB
gene_biotype: protein_coding
description:
  Agmatinase; Catalyzes the formation of putrescine from agmatine. Belongs to the arginase family. Agmatinase subfamily.


ensembl_gene_id: XNC1_1039
symbol: mutH
gene_biotype: protein_coding
description:
  Putative methyl-directed mismatch repair protein with restriction endonuclease-like domain; Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair. Belongs to the MutH family.


ensembl_gene_id: XNC1_1040
symbol: leuB
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.


ensembl_gene_id: XNC1_1041
symbol: leuA
gene_biotype: protein_coding
description:
  2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.


ensembl_gene_id: XNC1_1043
symbol: leuO
gene_biotype: protein_coding
description:
  LysR family transcriptional regulator, transcriptional activator for leuABCD operon; Putative transcriptional regulator of leucine biosynthesis with periplasmic binding protein domain (LysR family).


ensembl_gene_id: XNC1_1048
symbol: mraZ
gene_biotype: protein_coding
description:
  Protein mraZ; Negatively regulates its own expression and that of the subsequent genes in the proximal part of the division and cell wall (dcw) gene cluster. Acts by binding directly to DNA. May also regulate the expression of genes outside the dcw cluster.


ensembl_gene_id: XNC1_1049
symbol: mraW
gene_biotype: protein_coding
description:
  S-adenosyl-dependent methyl transferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.


ensembl_gene_id: XNC1_1050
symbol: ftsL
gene_biotype: protein_coding
description:
  Cell division protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.


ensembl_gene_id: XNC1_1051
symbol: ftsI
gene_biotype: protein_coding
description:
  Division-specific transpeptidase, penicillin-binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily.


ensembl_gene_id: XNC1_1052
symbol: murE
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoylalanyl-D-glutamate 2,6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.


ensembl_gene_id: XNC1_1053
symbol: murF
gene_biotype: protein_coding
description:
  D-alanine:D-alanine-adding enzyme; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.


ensembl_gene_id: XNC1_1054
symbol: mraY
gene_biotype: protein_coding
description:
  phospho-N-acetylmuramoyl-pentapeptide transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.


ensembl_gene_id: XNC1_1055
symbol: murD
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.


ensembl_gene_id: XNC1_1056
symbol: ftsW
gene_biotype: protein_coding
description:
  Essential cell division gene, stablilzes FtsZ ring, required for PBP2 expression; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily.


ensembl_gene_id: XNC1_1057
symbol: murG
gene_biotype: protein_coding
description:
  Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.


ensembl_gene_id: XNC1_1058
symbol: murC
gene_biotype: protein_coding
description:
  UDP-N-acetyl-muramate:alanine ligase, L-alanine adding enzyme; Cell wall formation; Belongs to the MurCDEF family.


ensembl_gene_id: XNC1_1059
symbol: ddlB
gene_biotype: protein_coding
description:
  D-alanine-D-alanine ligase B, affects cell division; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.


ensembl_gene_id: XNC1_1060
symbol: ftsQ
gene_biotype: protein_coding
description:
  Cell division protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.


ensembl_gene_id: XNC1_1061
symbol: ftsA
gene_biotype: protein_coding
description:
  Cell division protein with ATPase domain, involved in recruitment of FtsK to Z ring; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.


ensembl_gene_id: XNC1_1064
symbol: lpxC
gene_biotype: protein_coding
description:
  Tubulin-like GTP-binding protein and GTPase, forms circumferential ring in cell division (fragment); Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family.


ensembl_gene_id: XNC1_1066
symbol: secM
gene_biotype: protein_coding
description:
  Secretion monitor, regulator of secA translation (General Secretory Pathway); Regulates secA expression by translational coupling of the secM secA operon. Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation initiation. Belongs to the SecM family.


ensembl_gene_id: XNC1_1067
symbol: secA
gene_biotype: protein_coding
description:
  Preprotein translocase, ATPase secretion component (General Secretory Pathway); Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.


ensembl_gene_id: XNC1_1071
symbol: yacG
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C- terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.


ensembl_gene_id: XNC1_1072
symbol: zapD
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.


ensembl_gene_id: XNC1_1073
symbol: coaE
gene_biotype: protein_coding
description:
  dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.


ensembl_gene_id: XNC1_1075
symbol: hofB
gene_biotype: protein_coding
description:
  Putative integral membrane protein involved in biogenesis of fimbriae (type IV pilin), protein transport, DNA uptake with P-loop containing NTP hydrolysis domain.


ensembl_gene_id: XNC1_1080
symbol: aceE
gene_biotype: protein_coding
description:
  Pyruvate dehydrogenase, decarboxylase subunit, thiamin-binding; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


ensembl_gene_id: XNC1_1081
symbol: aceF
gene_biotype: protein_coding
description:
  Pyruvate dehydrogenase, dihydrolipoyltransacetylase subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


ensembl_gene_id: XNC1_1082
symbol: lpd
gene_biotype: protein_coding
description:
  Dihydrolipoamide dehydrogenase, FAD/NAD(P)-binding, component of the 2-oxoglutarate dehydrogenase and the pyruvate dehydrogenase complexes.


ensembl_gene_id: XNC1_1090
symbol: acnB
gene_biotype: protein_coding
description:
  Bifunctional: aconitate hydratase 2; 2-methylisocitrate dehydratase; Belongs to the aconitase/IPM isomerase family.


ensembl_gene_id: XNC1_1095
symbol: yggA
gene_biotype: protein_coding
description:
  Putative amino acid transport protein (LYSE family); Involved in the export of arginine. Important to control the intracellular level of arginine and the correct balance between arginine and lysine; Belongs to the LysE/ArgO transporter (TC 2.A.75) family.


ensembl_gene_id: XNC1_1097
symbol: argP
gene_biotype: protein_coding
description:
  Inhibitor of replication initiation; Controls the transcription of genes involved in arginine and lysine metabolism; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: XNC1_1098
symbol: rpiA
gene_biotype: protein_coding
description:
  Ribosephosphate isomerase, constitutive; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.


ensembl_gene_id: XNC1_1100
symbol: serA
gene_biotype: protein_coding
description:
  D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: XNC1_1103
symbol: XNC1_1103
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.


ensembl_gene_id: XNC1_1108
symbol: gcvT
gene_biotype: protein_coding
description:
  Glycine cleavage complex protein T, aminomethyltransferase, tetrahydrofolate-dependent; The glycine cleavage system catalyzes the degradation of glycine.


ensembl_gene_id: XNC1_1109
symbol: gcvH
gene_biotype: protein_coding
description:
  Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.


ensembl_gene_id: XNC1_1110
symbol: gcvP
gene_biotype: protein_coding
description:
  Glycine cleavage complex protein P, glycine decarboxylase, PLP-dependent; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.


ensembl_gene_id: XNC1_1119
symbol: XNC1_1119
gene_biotype: protein_coding
description:
  Putative transposase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.


ensembl_gene_id: XNC1_1126
symbol: ygfZ
gene_biotype: protein_coding
description:
  Putative enzyme; Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication; Belongs to the tRNA-modifying YgfZ family.


ensembl_gene_id: XNC1_1129
symbol: txp40
gene_biotype: protein_coding
description:
  Txp40, 40kDa insecticidal toxin (previously name A24tox); Function experimentally demonstrated in the studied species; phenotype.


ensembl_gene_id: XNC1_1133
symbol: fldB
gene_biotype: protein_coding
description:
  Flavodoxin 2; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family.


ensembl_gene_id: XNC1_1134
symbol: xerD
gene_biotype: protein_coding
description:
  Site-specific tyrosine recombinase; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerC binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerD specifically ex [...]


ensembl_gene_id: XNC1_1135
symbol: dsbC
gene_biotype: protein_coding
description:
  Protein disulfide isomerase II, activated by N-terminal of DsbD; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily.


ensembl_gene_id: XNC1_1137
symbol: prfB
gene_biotype: protein_coding
description:
  Peptide chain release factor RF-2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.


ensembl_gene_id: XNC1_1142
symbol: pirB
gene_biotype: protein_coding
description:
  JHE-like toxin, ''Photorhabdus insecticidal related'' toxin, PirB; Function of strongly homologous gene; factor.


ensembl_gene_id: XNC1_1143
symbol: pirA
gene_biotype: protein_coding
description:
  JHE-like toxin, ''Photorhabdus insecticidal related'' toxin, PirA; Function of strongly homologous gene; putative factor.


ensembl_gene_id: XNC1_1147
symbol: XNC1_1147
gene_biotype: protein_coding
description:
  Uroporphyrin-III C-methyltransferase (Urogen III methylase) (SUMT) (Uroporphyrinogen III methylase) (UROM); Belongs to the precorrin methyltransferase family.


ensembl_gene_id: XNC1_1149
symbol: cbiA
gene_biotype: protein_coding
description:
  Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.


ensembl_gene_id: XNC1_1150
symbol: cobD
gene_biotype: protein_coding
description:
  Cobalamin biosynthesis protein cbiB; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.


ensembl_gene_id: XNC1_1152
symbol: cbiD
gene_biotype: protein_coding
description:
  Putative cobalt-precorrin-6A synthase [deacetylating]; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.


ensembl_gene_id: XNC1_1153
symbol: XNC1_1153
gene_biotype: protein_coding
description:
  Cobalt-precorrin-7 (C5)-methyltransferase; Putative cobalt-precorrin-6Y C(5)-methyltransferase (Cobalt-precorrin-6 methyltransferase) (Cobalt-precorrin-6Y methylase).


ensembl_gene_id: XNC1_1157
symbol: XNC1_1157
gene_biotype: protein_coding
description:
  Cobalt-precorrin-3B C(17)-methyltransferase (Cobalt-precorrin-3 methyltransferase) (Cobalt-precorrin-3 methylase).


ensembl_gene_id: XNC1_1159
symbol: XNC1_1159
gene_biotype: protein_coding
description:
  Sirohydrochlorin cobaltochelatase; Catalyzes the insertion of Co(2+) into sirohydrochlorin. Belongs to the CbiK family.


ensembl_gene_id: XNC1_1160
symbol: XNC1_1160
gene_biotype: protein_coding
description:
  Precorrin-2/cobalt-factor-2 C20-methyltransferase; Cobalt-precorrin-2 C(20)-methyltransferase (S-adenosyl-L-methionine--cobalt-precorrin-2 methyltransferase); Belongs to the precorrin methyltransferase family.


ensembl_gene_id: XNC1_1161
symbol: cbiM
gene_biotype: protein_coding
description:
  Protein cbiM; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.


ensembl_gene_id: XNC1_1162
symbol: cbiN
gene_biotype: protein_coding
description:
  Cobalt transport protein cbiN; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import; Belongs to the CbiN family.


ensembl_gene_id: XNC1_1164
symbol: XNC1_1164
gene_biotype: protein_coding
description:
  Cobalt import ATP-binding protein cbiO; Part of an ABC transporter complex. Responsible for energy coupling to the transport system.


ensembl_gene_id: XNC1_1165
symbol: cobQ
gene_biotype: protein_coding
description:
  Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.


ensembl_gene_id: XNC1_1166
symbol: cobU
gene_biotype: protein_coding
description:
  Bifunctional: cobinamide kinase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.


ensembl_gene_id: XNC1_1167
symbol: cobS
gene_biotype: protein_coding
description:
  Cobalamin 5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.


ensembl_gene_id: XNC1_1168
symbol: cobC
gene_biotype: protein_coding
description:
  Putative alpha-ribazole-5'-Pphosphatase (cobalamin biosynthesis) with phosphoglycerate mutase-like domain.


ensembl_gene_id: XNC1_1169
symbol: cobT
gene_biotype: protein_coding
description:
  Nicotinate-nucleotide dimethylbenzimidazole-P phophoribosyl transferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).


ensembl_gene_id: XNC1_1170
symbol: pixA
gene_biotype: protein_coding
description:
  Methionine-rich PixA inclusion body protein; Function experimentally demonstrated in the studied strain; factor.


ensembl_gene_id: XNC1_1174
symbol: queH
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).


ensembl_gene_id: XNC1_1195
symbol: XNC1_1195
gene_biotype: protein_coding
description:
  Putative membrane protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.


ensembl_gene_id: XNC1_1217
symbol: aqpZ
gene_biotype: protein_coding
description:
  Water channel (aquaporin Z) (MIP family); Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity; Belongs to the MIP/aquaporin (TC 1.A.8) family.


ensembl_gene_id: XNC1_1226
symbol: XNC1_1226
gene_biotype: protein_coding
description:
  Putative acetyl-CoA synthetase of the propionate catabolism operon with firefly luciferase-like ATPase domain (fragment).


ensembl_gene_id: XNC1_1230
symbol: prpB
gene_biotype: protein_coding
description:
  2-methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.


ensembl_gene_id: XNC1_1239
symbol: XNC1_1239
gene_biotype: protein_coding
description:
  Putative trasnposase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: XNC1_1244
symbol: betA
gene_biotype: protein_coding
description:
  Choline dehydrogenase, a flavoprotein; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.


ensembl_gene_id: XNC1_1245
symbol: betB-2
gene_biotype: protein_coding
description:
  NAD+-dependent betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid.


ensembl_gene_id: XNC1_1246
symbol: betI
gene_biotype: protein_coding
description:
  Transcriptional repressor for the cellular response to osmotic stress (TetR/AcrR family); Repressor involved in choline regulation of the bet genes.


ensembl_gene_id: XNC1_1247
symbol: betT
gene_biotype: protein_coding
description:
  High-affinity choline transport protein (BCCT family); Belongs to the BCCT transporter (TC 2.A.15) family.


ensembl_gene_id: XNC1_1250
symbol: dinB
gene_biotype: protein_coding
description:
  DNA polymerase IV, devoid of proofreading, damage-inducible protein P; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.


ensembl_gene_id: XNC1_1252
symbol: gpt
gene_biotype: protein_coding
description:
  Guanine-hypoxanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.


ensembl_gene_id: XNC1_1254
symbol: crl
gene_biotype: protein_coding
description:
  Transcriptional regulator of cryptic genes for curli formation and fibronectin binding; Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32; Belongs to the Crl family.


ensembl_gene_id: XNC1_1255
symbol: proB
gene_biotype: protein_coding
description:
  Gamma-glutamate kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.


ensembl_gene_id: XNC1_1256
symbol: proA
gene_biotype: protein_coding
description:
  Gamma-glutamylphosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.


ensembl_gene_id: XNC1_1257
symbol: aroL
gene_biotype: protein_coding
description:
  Shikimate kinase II; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.


ensembl_gene_id: XNC1_1258
symbol: aas
gene_biotype: protein_coding
description:
  Bifunctional: 2-acylglycerophospho-ethanolamine acyl transferase (N-terminal); Plays a role in lysophospholipid acylation. Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1; In the C-terminal section; belongs to the ATP-dependent AMP-binding enzyme family.


ensembl_gene_id: XNC1_1261
symbol: recA
gene_biotype: protein_coding
description:
  DNA strand exchange and recombination protein with protease and nuclease activity; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.


ensembl_gene_id: XNC1_1262
symbol: alaS
gene_biotype: protein_coding
description:
  alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain; Belongs to the class-II aminoacyl-tRNA synthetase family.


ensembl_gene_id: XNC1_1263
symbol: csrA
gene_biotype: protein_coding
description:
  Translational regulator CsrA; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).


ensembl_gene_id: XNC1_1264
symbol: gshA
gene_biotype: protein_coding
description:
  Gamma-glutamate-cysteine ligase; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.


ensembl_gene_id: XNC1_1265
symbol: luxS
gene_biotype: protein_coding
description:
  Quorum-sensing protein, produces autoinducer-acyl-homoserine lactone-signaling molecules; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.


ensembl_gene_id: XNC1_1268
symbol: ffh
gene_biotype: protein_coding
description:
  4.5S-RNP protein, GTP-binding export factor, part of signal recognition particle with 4.5 RNA; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissoci [...]


ensembl_gene_id: XNC1_1270
symbol: rimM
gene_biotype: protein_coding
description:
  16S rRNA processing protein; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family.


ensembl_gene_id: XNC1_1271
symbol: trmD
gene_biotype: protein_coding
description:
  tRNA (guanine-7-)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.


ensembl_gene_id: XNC1_1272
symbol: rplS
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.


ensembl_gene_id: XNC1_1274
symbol: aroF
gene_biotype: protein_coding
description:
  3-deoxy-D-arabinoheptulosonate-7-phosphate synthase (DAHP synthetase), tyrosine-repressible; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP).


ensembl_gene_id: XNC1_1275
symbol: tyrA
gene_biotype: protein_coding
description:
  Bifunctional: chorismate mutase T (N-terminal); Function experimentally demonstrated in the studied strain; enzyme.


ensembl_gene_id: XNC1_1276
symbol: pheA
gene_biotype: protein_coding
description:
  Bifunctional: chorismate mutase P (N-terminal); Function experimentally demonstrated in the studied strain; enzyme.


ensembl_gene_id: XNC1_1279
symbol: ecfD
gene_biotype: protein_coding
description:
  Putative lipoprotein with tetratricopeptide repeats (TPR) domain; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamA, the core component of the assembly machinery.


ensembl_gene_id: XNC1_1280
symbol: rluD
gene_biotype: protein_coding
description:
  Pseudouridine synthase (pseudouridines 1911, 1915, 1917 in 23S RNA); Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.


ensembl_gene_id: XNC1_1283
symbol: clpB
gene_biotype: protein_coding
description:
  ATP-dependent protease, Hsp 100, part of multi-chaperone system with DnaK, DnaJ, and GrpE; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.


ensembl_gene_id: XNC1_1296
symbol: yfiF
gene_biotype: protein_coding
description:
  Putative tRNA/rRNA methyltransferase; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.


ensembl_gene_id: XNC1_1298
symbol: xhbF
gene_biotype: protein_coding
description:
  Putative siderophore biosynthetic enzyme; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: XNC1_1299
symbol: XNC1_1299
gene_biotype: protein_coding
description:
  FhuE receptor (Outer-membrane receptor for ferric iron uptake); Function of strongly homologous gene; receptor.


ensembl_gene_id: XNC1_1300
symbol: XNC1_1300
gene_biotype: protein_coding
description:
  Ferric enterobactin binding periplasmic protein FepB; Function of strongly homologous gene; transporter.


ensembl_gene_id: XNC1_1301
symbol: fepD
gene_biotype: protein_coding
description:
  Ferric enterobactin transport protein (ABC superfamily, membrane); Function of strongly homologous gene; transporter; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: XNC1_1302
symbol: XNC1_1302
gene_biotype: protein_coding
description:
  Ferric enterobactin transport system permease protein FepG; Function of strongly homologous gene; transporter; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: XNC1_1303
symbol: fepC
gene_biotype: protein_coding
description:
  Ferric enterobactin transport protein (ABC superfamily, atp_bind); Function of strongly homologous gene; transporter.


ensembl_gene_id: XNC1_1306
symbol: XNC1_1306
gene_biotype: protein_coding
description:
  Putative siderophore biosynthesis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.


ensembl_gene_id: XNC1_1320
symbol: ogt
gene_biotype: protein_coding
description:
  Methylated-DNA--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.


ensembl_gene_id: XNC1_1322
symbol: crcB
gene_biotype: protein_coding
description:
  Crc interacts with Csp affecting chromosome condensation; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.


ensembl_gene_id: XNC1_1323
symbol: lipA
gene_biotype: protein_coding
description:
  Lipoate protein ligase, an iron-sulfur enzyme; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.


ensembl_gene_id: XNC1_1324
symbol: lipB
gene_biotype: protein_coding
description:
  Lipoyl(octanyl)-acyl carrier protein: protein transferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.


ensembl_gene_id: XNC1_1325
symbol: trkG
gene_biotype: protein_coding
description:
  Rac prophage; Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA; Belongs to the TrkH potassium transport family.


ensembl_gene_id: XNC1_1327
symbol: dacA
gene_biotype: protein_coding
description:
  D-alanyl-D-alanine carboxypeptidase, penicillin-binding protein 5; Belongs to the peptidase S11 family.


ensembl_gene_id: XNC1_1328
symbol: rlpA
gene_biotype: protein_coding
description:
  A minor lipoprotein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.


ensembl_gene_id: XNC1_1332
symbol: mrdA
gene_biotype: protein_coding
description:
  Cell elongation-specific transpeptidase of penicillin-binding protein 2 (peptidoglycan synthetase); Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.


ensembl_gene_id: XNC1_1333
symbol: rlmH
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family.


ensembl_gene_id: XNC1_1334
symbol: rsfS
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.


ensembl_gene_id: XNC1_1335
symbol: nadD
gene_biotype: protein_coding
description:
  Nicotinic acid mononucleotide adenylyltransferase, NAD(P)-requiring; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).


ensembl_gene_id: XNC1_1337
symbol: rlpB
gene_biotype: protein_coding
description:
  A minor lipoprotein; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.


ensembl_gene_id: XNC1_1343
symbol: cutE
gene_biotype: protein_coding
description:
  Apolipoprotein N-acyltransferase, copper homeostasis protein, inner membrane; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily.


ensembl_gene_id: XNC1_1345
symbol: ybeY
gene_biotype: protein_coding
description:
  Putative metal-dependent hydrolase; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.


ensembl_gene_id: XNC1_1346
symbol: ybeZ
gene_biotype: protein_coding
description:
  Phosphate starvation-inducible protein PhoH and related proteins; Putative phosphate starvation-inducible protein (ATP-binding) with P-loop containing NTP hydrolase domain.


ensembl_gene_id: XNC1_1347
symbol: miaB
gene_biotype: protein_coding
description:
  Involved in methylthiolation of isopentenylated A37 derivatives in tRNA, Fe-S protein; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.


ensembl_gene_id: XNC1_1356
symbol: nagB
gene_biotype: protein_coding
description:
  Glucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.


ensembl_gene_id: XNC1_1357
symbol: nagE
gene_biotype: protein_coding
description:
  PTS family enzyme IIC (N-terminal); enzyme IIB (center); enzyme IIA (C-terminal), N-acetylglucosamine-specific.


ensembl_gene_id: XNC1_1359
symbol: XNC1_1359
gene_biotype: protein_coding
description:
  Chitobiase precursor (N-acetyl-beta-glucosaminidase) (Beta-N-acetylhexosaminidase); Function of strongly homologous gene; enzyme.


ensembl_gene_id: XNC1_1361
symbol: fldA
gene_biotype: protein_coding
description:
  Flavodoxin 1; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family.


ensembl_gene_id: XNC1_1382
symbol: XNC1_1382
gene_biotype: protein_coding
description:
  Putative membrane protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative membrane component.


ensembl_gene_id: XNC1_1386
symbol: seqA
gene_biotype: protein_coding
description:
  Negative modulator of replication initiation; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated.


ensembl_gene_id: XNC1_1393
symbol: XNC1_1393
gene_biotype: protein_coding
description:
  Pullulanase precursor (Alpha-dextrin endo-1,6-alpha-glucosidase) (Pullulan 6-glucanohydrolase); Belongs to the glycosyl hydrolase 13 family.


ensembl_gene_id: XNC1_1394
symbol: kdpE
gene_biotype: protein_coding
description:
  Response regulator in two-component regulatory system with KdpD, regulation of potassium translocation (OmpR family).


ensembl_gene_id: XNC1_1395
symbol: kdpD
gene_biotype: protein_coding
description:
  Sensory histidine kinase in two-component regulatory system wtih KdpE, regulation of potassium translocation.


ensembl_gene_id: XNC1_1396
symbol: kdpC
gene_biotype: protein_coding
description:
  P-type ATPase, high-affinity potassium transport system, C chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.


ensembl_gene_id: XNC1_1397
symbol: kdpB
gene_biotype: protein_coding
description:
  P-type ATPase, high-affinity potassium transport system, B chain, a phophatase-like domain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.


ensembl_gene_id: XNC1_1398
symbol: kdpA
gene_biotype: protein_coding
description:
  P-type ATPase, high-affinity potassium transport system, A chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane.


ensembl_gene_id: XNC1_1406
symbol: sdhD
gene_biotype: protein_coding
description:
  Succinate dehydrogenase, hydrophobic subunit, cytochrome b556 with SdhC; Membrane-anchoring subunit of succinate dehydrogenase (SDH).


ensembl_gene_id: XNC1_1407
symbol: sdhA
gene_biotype: protein_coding
description:
  Succinate dehydrogenase, catalytic and NAD/flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.


ensembl_gene_id: XNC1_1408
symbol: sdhB
gene_biotype: protein_coding
description:
  Succinate dehydrogenase, Fe-S protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.


ensembl_gene_id: XNC1_1409
symbol: sucA
gene_biotype: protein_coding
description:
  2-oxoglutarate decarboxylase, component of the 2-oxoglutarate dehydrogenase complex, thiamin-binding.


ensembl_gene_id: XNC1_1410
symbol: sucB
gene_biotype: protein_coding
description:
  Dihydrolipoyltranssuccinate transferase, component of the 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).


ensembl_gene_id: XNC1_1411
symbol: sucC
gene_biotype: protein_coding
description:
  succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.


ensembl_gene_id: XNC1_1412
symbol: sucD
gene_biotype: protein_coding
description:
  succinyl-CoA synthetase, alpha subunit, NAD(P)-binding; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.


ensembl_gene_id: XNC1_1417
symbol: tolQ
gene_biotype: protein_coding
description:
  Tol-Pal system protein TolQ; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolR, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.


ensembl_gene_id: XNC1_1418
symbol: tolR
gene_biotype: protein_coding
description:
  Tol-Pal system protein TolR; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolQ, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.


ensembl_gene_id: XNC1_1419
symbol: tolA
gene_biotype: protein_coding
description:
  Colicin import membrane protein; Required for outer membrane integrity, uptake of group A colicins, role in translocation of filamenous phage DNA to cytoplasm, role in surface expression of O-antigen.


ensembl_gene_id: XNC1_1420
symbol: tolB
gene_biotype: protein_coding
description:
  Required for outer membrane integrity, uptake of group A colicins, and translocation of phage DNA; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.


ensembl_gene_id: XNC1_1421
symbol: pal
gene_biotype: protein_coding
description:
  Required for outer membrane integrity, uptake of group A colicins, and translocation of phage DNA; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: XNC1_1422
symbol: ybgF
gene_biotype: protein_coding
description:
  Putative periplasmic protein contains a protein prenylyltransferase domain; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family.


ensembl_gene_id: XNC1_1424
symbol: aroG
gene_biotype: protein_coding
description:
  3-deoxy-D-arabinoheptulosonate-7-phosphate synthase (DAHP synthetase, phenylalanine-repressible); Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP).


ensembl_gene_id: XNC1_1425
symbol: gpmA
gene_biotype: protein_coding
description:
  Phosphoglyceromutase 1; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.


ensembl_gene_id: XNC1_1430
symbol: acrZ
gene_biotype: protein_coding
description:
  Hypothetical protein; AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export.


ensembl_gene_id: XNC1_1433
symbol: modB
gene_biotype: protein_coding
description:
  Molybdate transport protein (ABC superfamily, membrane); Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: XNC1_1434
symbol: modC
gene_biotype: protein_coding
description:
  Molybdate transport protein (ABC superfamily, atp_bind); Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Molybdate importer (TC 3.A.1.8) family.


ensembl_gene_id: XNC1_1440
symbol: bioA
gene_biotype: protein_coding
description:
  7,8-diaminopelargonic acid synthetase, PLP-dependent; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.


ensembl_gene_id: XNC1_1441
symbol: bioB
gene_biotype: protein_coding
description:
  Biotin synthetase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.


ensembl_gene_id: XNC1_1442
symbol: bioF
gene_biotype: protein_coding
description:
  7-keto-8-aminopelargonic acid synthetase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.


ensembl_gene_id: XNC1_1443
symbol: bioC
gene_biotype: protein_coding
description:
  Biotin biosynthesis; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.


ensembl_gene_id: XNC1_1444
symbol: bioD
gene_biotype: protein_coding
description:
  Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. Belongs to the dethiobiotin synthetase family.


ensembl_gene_id: XNC1_1446
symbol: uvrB
gene_biotype: protein_coding
description:
  ATP-dependent DNA excision repair enzyme UvrAC; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA  [...]


ensembl_gene_id: XNC1_1447
symbol: ybhK
gene_biotype: protein_coding
description:
  Putative phosphatase/sulfatase with NAD(P)-binding domain; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family.


ensembl_gene_id: XNC1_1448
symbol: XNC1_1448
gene_biotype: protein_coding
description:
  Molybdopterin biosynthesis protein A (fragment); Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.


ensembl_gene_id: XNC1_1449
symbol: moaC
gene_biotype: protein_coding
description:
  Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.


ensembl_gene_id: XNC1_1460
symbol: rhlE
gene_biotype: protein_coding
description:
  Putative ATP-dependent RNA helicase with P-loop hydrolase domain; DEAD-box RNA helicase involved in ribosome assembly. Has RNA- dependent ATPase activity and unwinds double-stranded RNA.


ensembl_gene_id: XNC1_1461
symbol: dusC
gene_biotype: protein_coding
description:
  tRNA-dihydrouridine synthase C; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs. Belongs to the Dus family. DusC subfamily.


ensembl_gene_id: XNC1_1486
symbol: moeA
gene_biotype: protein_coding
description:
  Molybdopterin biosynthesis protein, molybdenum incorporation step; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.


ensembl_gene_id: XNC1_1493
symbol: cdd
gene_biotype: protein_coding
description:
  Cytidine/deoxycytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.


ensembl_gene_id: XNC1_1496
symbol: metG
gene_biotype: protein_coding
description:
  Methionine tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.


ensembl_gene_id: XNC1_1497
symbol: mrp
gene_biotype: protein_coding
description:
  Putative ATP-binding protein with nucleotide triphosphate hydrolase domain; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.


ensembl_gene_id: XNC1_1504
symbol: gnd
gene_biotype: protein_coding
description:
  Gluconate-6-phosphate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.


ensembl_gene_id: XNC1_1511
symbol: XNC1_1511
gene_biotype: protein_coding
description:
  Arsenite methyltransferase (S-adenosyl-L-methionine:arsenic(III) methyltransferase) (Methylarsonite methyltransferase).


ensembl_gene_id: XNC1_1513
symbol: hisI
gene_biotype: protein_coding
description:
  Bifunctional: phosphoribosyl-AMP cyclohydrolase (N-terminal); phosphoribosyl-ATP pyrophosphatase (C-terminal); In the N-terminal section; belongs to the PRA-CH family.


ensembl_gene_id: XNC1_1514
symbol: hisF
gene_biotype: protein_coding
description:
  Imidazole glycerol phosphate synthase, subunit with HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.


ensembl_gene_id: XNC1_1516
symbol: hisH
gene_biotype: protein_coding
description:
  Glutamine amidotransferase, subunit with HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.


ensembl_gene_id: XNC1_1517
symbol: hisB
gene_biotype: protein_coding
description:
  Modular bifunctional: histidinol-phosphatase (N-terminal); Function experimentally demonstrated in the studied strain; enzyme; In the N-terminal section; belongs to the histidinol- phosphatase family.


ensembl_gene_id: XNC1_1518
symbol: hisC
gene_biotype: protein_coding
description:
  Histidinol phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.


ensembl_gene_id: XNC1_1519
symbol: hisD
gene_biotype: protein_coding
description:
  Bifunctional HisD: L-histidinal:NAD+ dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.


ensembl_gene_id: XNC1_1520
symbol: hisG
gene_biotype: protein_coding
description:
  ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.


ensembl_gene_id: XNC1_1522
symbol: yliJ
gene_biotype: protein_coding
description:
  Putative glutathione S-transferase with thioredoxin-like domain and glutathione S-transferase, C-terminal domain.


ensembl_gene_id: XNC1_1523
symbol: dacC
gene_biotype: protein_coding
description:
  D-alanyl-D-alanine carboxypeptidase; penicillin-binding protein 6a; Belongs to the peptidase S11 family.


ensembl_gene_id: XNC1_1533
symbol: ybjF
gene_biotype: protein_coding
description:
  23S rRNA (uracil(747)-C(5))-methyltransferase RlmC; Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmC subfamily.


ensembl_gene_id: XNC1_1536
symbol: artI
gene_biotype: protein_coding
description:
  Arginine transport protein (ABC superfamily, peri_bind); Belongs to the bacterial solute-binding protein 3 family.


ensembl_gene_id: XNC1_1541
symbol: clpS
gene_biotype: protein_coding
description:
  Modulator of ClpA substrate specificity; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family.


ensembl_gene_id: XNC1_1543
symbol: infA
gene_biotype: protein_coding
description:
  Protein chain initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.


ensembl_gene_id: XNC1_1544
symbol: aat
gene_biotype: protein_coding
description:
  Leucyl, phenylalanyl-tRNA-protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.


ensembl_gene_id: XNC1_1545
symbol: cydC
gene_biotype: protein_coding
description:
  Cysteine transport (export) protein (ABC superfamily, membrane (N-terminal), atp_bind (C-terminal)).


ensembl_gene_id: XNC1_1548
symbol: lrp
gene_biotype: protein_coding
description:
  Leucine-responsive regulatory protein; Function experimentally demonstrated in the studied strain; regulator.


ensembl_gene_id: XNC1_1550
symbol: lolA
gene_biotype: protein_coding
description:
  Periplasmic chaperone effects translocation of lipoproteins from inner membrane to outer membrane; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).


ensembl_gene_id: XNC1_1552
symbol: serS
gene_biotype: protein_coding
description:
  Serine tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).


ensembl_gene_id: XNC1_1556
symbol: pflA
gene_biotype: protein_coding
description:
  Pyruvate formate lyase activating enzyme 1; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family.


ensembl_gene_id: XNC1_1561
symbol: XNC1_1561
gene_biotype: protein_coding
description:
  Putative Nonribosomal peptide synthase (NRPS); Belongs to the ATP-dependent AMP-binding enzyme family.


ensembl_gene_id: XNC1_1562
symbol: serC
gene_biotype: protein_coding
description:
  3-phosphoserine/phosphohydroxythreonine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.


ensembl_gene_id: XNC1_1563
symbol: aroA
gene_biotype: protein_coding
description:
  3-enolpyruvylshikimate-5-phosphate synthetase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.


ensembl_gene_id: XNC1_1565
symbol: rpsA
gene_biotype: protein_coding
description:
  30S ribosomal subunit protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.


ensembl_gene_id: XNC1_1566
symbol: ihfB
gene_biotype: protein_coding
description:
  Integration host factor (IHF), beta subunit, site-specific recombination; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.


ensembl_gene_id: XNC1_1568
symbol: msbA
gene_biotype: protein_coding
description:
  Lipid transport protein, flippase (ABC superfamily, membrane (N-terminal), atp_bind (C-terminal)); Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.


ensembl_gene_id: XNC1_1569
symbol: lpxK
gene_biotype: protein_coding
description:
  Tetraacyldisaccharide 4' kinase (lipid A 4'kinase); Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).


ensembl_gene_id: XNC1_1571
symbol: kdsB
gene_biotype: protein_coding
description:
  CTP:CMP-3-deoxy-D-manno-octulosonate transferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.


ensembl_gene_id: XNC1_1574
symbol: smtA
gene_biotype: protein_coding
description:
  S-adenosylmethionine-dependent methyltransferase; Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs; Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoM family.


ensembl_gene_id: XNC1_1575
symbol: mukF
gene_biotype: protein_coding
description:
  mukF protein (killing factor KICB); Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity.


ensembl_gene_id: XNC1_1576
symbol: mukE
gene_biotype: protein_coding
description:
  Putative killing protein suppressor; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF.


ensembl_gene_id: XNC1_1577
symbol: mukB
gene_biotype: protein_coding
description:
  Kinesin-like cell division protein involved in sister chromosome partitioning; Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division; Belongs to the SMC family. MukB subfamily.


ensembl_gene_id: XNC1_1586
symbol: opnP
gene_biotype: protein_coding
description:
  Outer membrane protein, OpnP; Forms pores that allow passive diffusion of small molecules across the outer membrane.


ensembl_gene_id: XNC1_1588
symbol: pncB
gene_biotype: protein_coding
description:
  Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family.


ensembl_gene_id: XNC1_1591
symbol: pyrD
gene_biotype: protein_coding
description:
  Dihydro-orotate oxidase, FMN-linked; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.


ensembl_gene_id: XNC1_1592
symbol: zapC
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ.


ensembl_gene_id: XNC1_1594
symbol: ycbY
gene_biotype: protein_coding
description:
  Putative methyltransferase with S-adenosyl-L-methionine-dependent methyltransferase domain; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family.


ensembl_gene_id: XNC1_1600
symbol: rmf
gene_biotype: protein_coding
description:
  Ribosome modulation factor; During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes); Belongs to the ribosome modulation factor family.


ensembl_gene_id: XNC1_1601
symbol: fabA
gene_biotype: protein_coding
description:
  Beta-hydroxydecanoyl thioester dehydrase (trans-2-decenoyl-ACP isomerase); Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.


ensembl_gene_id: XNC1_1603
symbol: matP
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain.


ensembl_gene_id: XNC1_1605
symbol: sulA
gene_biotype: protein_coding
description:
  Cell division inhibitor SulA; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.


ensembl_gene_id: XNC1_1615
symbol: cheZ
gene_biotype: protein_coding
description:
  Chemotactic response, CheY protein phophatase; Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).


ensembl_gene_id: XNC1_1616
symbol: cheY
gene_biotype: protein_coding
description:
  Two-component system, chemotaxis family, chemotaxis protein CheY; Chemotactic response regulator in two-component regulatory system with CheA, transmits signals to FliM flagelllar motor component.


ensembl_gene_id: XNC1_1617
symbol: cheB
gene_biotype: protein_coding
description:
  Chemotactic response regulator; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.


ensembl_gene_id: XNC1_1618
symbol: cheR
gene_biotype: protein_coding
description:
  Glutamate methyltransferase, chemotactic response regulator; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.


ensembl_gene_id: XNC1_1623
symbol: cheA
gene_biotype: protein_coding
description:
  Two-component system, chemotaxis family, sensor kinase CheA; Chemotactic sensory histidine kinase (soluble) in two-component regulatory system with CheB and CheY, senses chemotactic signal.


ensembl_gene_id: XNC1_1626
symbol: flhC
gene_biotype: protein_coding
description:
  Flagellar transcriptional regulator FlhC; Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhC family.


ensembl_gene_id: XNC1_1627
symbol: flhD
gene_biotype: protein_coding
description:
  Flagellar transcriptional regulator FlhD; Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhD family.


ensembl_gene_id: XNC1_1643
symbol: XNC1_1643
gene_biotype: protein_coding
description:
  Putative L-lactate permease; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family.


ensembl_gene_id: XNC1_1644
symbol: lldD
gene_biotype: protein_coding
description:
  L-lactate dehydrogenase, FMN-linked; Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain; Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.


ensembl_gene_id: XNC1_1650
symbol: lpxL
gene_biotype: protein_coding
description:
  Lauroyl transferase; Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A).


ensembl_gene_id: XNC1_1672
symbol: putP
gene_biotype: protein_coding
description:
  Major sodium:proline symporter (SSS family); Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: XNC1_1673
symbol: putA
gene_biotype: protein_coding
description:
  Multifunctional: transcriptional repressor of proline utilization; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: XNC1_1675
symbol: fliA
gene_biotype: protein_coding
description:
  RNA polymerase sigma factor FliA; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily.


ensembl_gene_id: XNC1_1676
symbol: XNC1_1676
gene_biotype: protein_coding
description:
  Flagellin; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.


ensembl_gene_id: XNC1_1677
symbol: fliD
gene_biotype: protein_coding
description:
  Flagellar biosynthesis; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.


ensembl_gene_id: XNC1_1683
symbol: fliF
gene_biotype: protein_coding
description:
  Flagellar biosynthesis; The M ring may be actively involved in energy transduction. Belongs to the FliF family.


ensembl_gene_id: XNC1_1684
symbol: fliG
gene_biotype: protein_coding
description:
  Flagellar biosynthesis; FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.


ensembl_gene_id: XNC1_1687
symbol: fliJ
gene_biotype: protein_coding
description:
  Flagellar fliJ protein; Flagellar protein that affects chemotactic events. Belongs to the FliJ family.


ensembl_gene_id: XNC1_1689
symbol: fliL
gene_biotype: protein_coding
description:
  Flagellar biosynthesis; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.


ensembl_gene_id: XNC1_1690
symbol: fliM
gene_biotype: protein_coding
description:
  Flagellar biosynthesis; FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.


ensembl_gene_id: XNC1_1691
symbol: fliN
gene_biotype: protein_coding
description:
  Flagellar biosynthesis; FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliN/MopA/SpaO family.


ensembl_gene_id: XNC1_1693
symbol: fliP
gene_biotype: protein_coding
description:
  Flagellar biosynthesis; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family.


ensembl_gene_id: XNC1_1695
symbol: fliR
gene_biotype: protein_coding
description:
  Putative flagellar biosynthetic protein, regulator; Role in flagellar biosynthesis. Belongs to the FliR/MopE/SpaR family.


ensembl_gene_id: XNC1_1697
symbol: speH
gene_biotype: protein_coding
description:
  Putative Adenosylmethionine decarboxylase; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.


ensembl_gene_id: XNC1_1698
symbol: xcnN
gene_biotype: protein_coding
description:
  Fatty acid desaturase involved in xenocoumacin synthesis; Function experimentally demonstrated in the studied strain; enzyme.


ensembl_gene_id: XNC1_1699
symbol: xcnM
gene_biotype: protein_coding
description:
  Saccharopine dehydrogenase involved in xenocoumacin synthesis; Function experimentally demonstrated in the studied strain; enzyme.


ensembl_gene_id: XNC1_1700
symbol: xcnL
gene_biotype: protein_coding
description:
  Polyketide synthase involved in xenocoumacin synthesis; Function experimentally demonstrated in the studied strain; enzyme.


ensembl_gene_id: XNC1_1701
symbol: xcnK
gene_biotype: protein_coding
description:
  Non-ribosomal peptide synthase involved in xenocoumacin synthesis; Function experimentally demonstrated in the studied strain; enzyme.


ensembl_gene_id: XNC1_1702
symbol: xcnJ
gene_biotype: protein_coding
description:
  Conserved hypothetical protein involved in xenocoumacin synthesis; Homologs of previously reported genes of unknown function; 1955881.


ensembl_gene_id: XNC1_1703
symbol: xcnI
gene_biotype: protein_coding
description:
  Thioesterase involved in xenocoumacin synthesis; Function experimentally demonstrated in the studied strain; enzyme.


ensembl_gene_id: XNC1_1705
symbol: xcnG
gene_biotype: protein_coding
description:
  Beta-lactamase class C involved in xenocoumacin synthesis; Function experimentally demonstrated in the studied strain; enzyme.


ensembl_gene_id: XNC1_1707
symbol: xcnE
gene_biotype: protein_coding
description:
  Acyl-CoA dehydrogenase involved in xenocoumacin synthesis; Function experimentally demonstrated in the studied strain; enzyme.


ensembl_gene_id: XNC1_1708
symbol: xcnD
gene_biotype: protein_coding
description:
  Putative acyl carrier protein potentially involved in xenocoumacin synthesis; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: XNC1_1709
symbol: xcnC
gene_biotype: protein_coding
description:
  Methoxymalonate biosynthesis protein involved in xenocoumacin synthesis; Function experimentally demonstrated in the studied strain; enzyme.


ensembl_gene_id: XNC1_1710
symbol: xcnB
gene_biotype: protein_coding
description:
  3-hydroxyacyl-CoA dehydrogenase involved in xenocoumacin synthesis; Function experimentally demonstrated in the studied strain; enzyme.


ensembl_gene_id: XNC1_1711
symbol: xcnA
gene_biotype: protein_coding
description:
  Non-ribosomal peptide synthase involved in Xenocoumacin synthesis; Function experimentally demonstrated in the studied strain; enzyme.


ensembl_gene_id: XNC1_1720
symbol: flgI
gene_biotype: protein_coding
description:
  Putative flagella basal body protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.


ensembl_gene_id: XNC1_1722
symbol: flgH
gene_biotype: protein_coding
description:
  Flagellar biosynthesis; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.


ensembl_gene_id: XNC1_1728
symbol: flgB
gene_biotype: protein_coding
description:
  Flagellar biosynthesis; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.


ensembl_gene_id: XNC1_1729
symbol: flgA
gene_biotype: protein_coding
description:
  Flagellar biosynthesis; Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P- ring assembly; Belongs to the FlgA family.


ensembl_gene_id: XNC1_1733
symbol: fimD
gene_biotype: protein_coding
description:
  Putative fimbrial protein FimA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative structure.


ensembl_gene_id: XNC1_1734
symbol: fimC
gene_biotype: protein_coding
description:
  Putative periplasmic chaperone protein with PapD-like and periplasmic chaperone C-domains; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative carrier.


ensembl_gene_id: XNC1_1735
symbol: fimA
gene_biotype: protein_coding
description:
  Putative Fimbrial subunit (pilin); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative structure.


ensembl_gene_id: XNC1_1736
symbol: flhA
gene_biotype: protein_coding
description:
  Putative export protein for flagellar biosynthesis; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.


ensembl_gene_id: XNC1_1737
symbol: flhB
gene_biotype: protein_coding
description:
  Putative part of export apparatus for flagellar proteins; Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the type III secretion exporter family.


ensembl_gene_id: XNC1_1756
symbol: XNC1_1756
gene_biotype: protein_coding
description:
  Putative polyketide synthase pksJ (PKS); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: XNC1_1762
symbol: XNC1_1762
gene_biotype: protein_coding
description:
  Putative Phenylalanine racemase (ATP-hydrolyzing); Belongs to the ATP-dependent AMP-binding enzyme family.


ensembl_gene_id: XNC1_1768
symbol: XNC1_1768
gene_biotype: protein_coding
description:
  Putative polyketide beta-ketoacyl synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: XNC1_1778
symbol: XNC1_1778
gene_biotype: protein_coding
description:
  Putative Resolvase/recombinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: XNC1_1779
symbol: XNC1_1779
gene_biotype: protein_coding
description:
  Putative surface protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.


ensembl_gene_id: XNC1_1793
symbol: proQ
gene_biotype: protein_coding
description:
  Putative structural element which influences activation of ProP; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities. May regulate ProP activity through an RNA-based, post-transcriptional mechanism. Belongs to the ProQ family.


ensembl_gene_id: XNC1_1797
symbol: ydjN
gene_biotype: protein_coding
description:
  Putative transport protein; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: XNC1_1806
symbol: XNC1_1806
gene_biotype: protein_coding
description:
  Putative RNA-directed DNA polymerase (fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: XNC1_1809
symbol: XNC1_1809
gene_biotype: protein_coding
description:
  Putative reverse transcriptase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: XNC1_1819
symbol: XNC1_1819
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the fructosamine kinase family.


ensembl_gene_id: XNC1_1820
symbol: XNC1_1820
gene_biotype: protein_coding
description:
  Chelated iron transport system membrane protein yfeD; Function of strongly homologous gene; membrane component.


ensembl_gene_id: XNC1_1821
symbol: XNC1_1821
gene_biotype: protein_coding
description:
  Chelated iron transport system membrane protein yfeC; Function of strongly homologous gene; membrane component.


ensembl_gene_id: XNC1_1822
symbol: XNC1_1822
gene_biotype: protein_coding
description:
  Chelated iron transport system membrane protein yfeB; Function of strongly homologous gene; membrane component.


ensembl_gene_id: XNC1_1823
symbol: XNC1_1823
gene_biotype: protein_coding
description:
  Periplasmic chelated iron-binding protein yfeA precursor; Function of strongly homologous gene; membrane component; Belongs to the bacterial solute-binding protein 9 family.


ensembl_gene_id: XNC1_1824
symbol: XNC1_1824
gene_biotype: protein_coding
description:
  Lytic murein endotransglycosylase E, membrane-bound (fragment); Function of strongly homologous gene; enzyme.


ensembl_gene_id: XNC1_1825
symbol: thrS
gene_biotype: protein_coding
description:
  Threonine tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).


ensembl_gene_id: XNC1_1828
symbol: rplT
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L20, also posttranslational autoregulator; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.


ensembl_gene_id: XNC1_1830
symbol: pheS
gene_biotype: protein_coding
description:
  Phenylalanine tRNA synthetase, alpha-subunit; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.


ensembl_gene_id: XNC1_1831
symbol: pheT
gene_biotype: protein_coding
description:
  Phenylalanine tRNA synthetase, beta-subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.


ensembl_gene_id: XNC1_1832
symbol: ihfA
gene_biotype: protein_coding
description:
  Integration host factor (IHF), alpha subunit, DNA-bending protein, DNA replication; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.


ensembl_gene_id: XNC1_1833
symbol: btuC
gene_biotype: protein_coding
description:
  Vitamin B12 transport protein (ABC superfamily, membrane); Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane.


ensembl_gene_id: XNC1_1834
symbol: btuD
gene_biotype: protein_coding
description:
  Vitamin B12 transport protein (ABC superfamily, atp_bind); Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system.


ensembl_gene_id: XNC1_1835
symbol: pgbP1
gene_biotype: protein_coding
description:
  UDP-4-amino-4-deoxy-L-arabinose-oxoglutarate aminotransferase; Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; Belongs to the DegT/DnrJ/EryC1 family. ArnB subfamily.


ensembl_gene_id: XNC1_1836
symbol: pbgP2
gene_biotype: protein_coding
description:
  Putative sugar transferase with nucleotide-diphospho-sugar transferase domain; Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.


ensembl_gene_id: XNC1_1837
symbol: pbgP3
gene_biotype: protein_coding
description:
  Putative formyltransferase; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; In the N-terminal section; belongs to the Fmt family. UDP- L-Ara4N formyltransferase subfamily.


ensembl_gene_id: XNC1_1838
symbol: pbgP4
gene_biotype: protein_coding
description:
  PbgP4 protein; Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; Belongs to the polysaccharide deacetylase family. ArnD deformylase subfamily.


ensembl_gene_id: XNC1_1839
symbol: pbgE1
gene_biotype: protein_coding
description:
  4-amino-4-deoxy-L-arabinose transferase (lipid A modification); Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides. Belongs to the glycosyltransferase 83 family.


ensembl_gene_id: XNC1_1840
symbol: pbgE2
gene_biotype: protein_coding
description:
  Inner membrane protein yfbW; Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane; Belongs to the ArnE family.


ensembl_gene_id: XNC1_1841
symbol: pbgE3
gene_biotype: protein_coding
description:
  Putative membrane protein; Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane; Belongs to the ArnF family.


ensembl_gene_id: XNC1_1853
symbol: hmuV
gene_biotype: protein_coding
description:
  Hemin transport system ATP-binding protein hmuV; Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system.


ensembl_gene_id: XNC1_1854
symbol: btuC-2
gene_biotype: protein_coding
description:
  Vitamin B12 transport protein (ABC superfamily, membrane); Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: XNC1_1860
symbol: XNC1_1860
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.


ensembl_gene_id: XNC1_1861
symbol: pps
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.


ensembl_gene_id: XNC1_1871
symbol: mdtK
gene_biotype: protein_coding
description:
  Multidrug transport protein (MATE family); Multidrug efflux pump that functions probably as a Na(+)/drug antiporter; Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MdtK subfamily.


ensembl_gene_id: XNC1_1875
symbol: ydhB
gene_biotype: protein_coding
description:
  Putative transcriptional regulator with periplasmic binding protein domain (LysR familiy); Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: XNC1_1876
symbol: purR
gene_biotype: protein_coding
description:
  Transcriptional repressor for de novo purine nucleotide synthesis (GalR/LacI family); Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression.


ensembl_gene_id: XNC1_1877
symbol: sodB
gene_biotype: protein_coding
description:
  Superoxide dismutase, iron; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.


ensembl_gene_id: XNC1_1879
symbol: rnt
gene_biotype: protein_coding
description:
  RNase T, degrades tRNA, has exonuclease and ssDNAse activity; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.


ensembl_gene_id: XNC1_1880
symbol: gloA
gene_biotype: protein_coding
description:
  Glyoxalase I, nickel isomerase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.


ensembl_gene_id: XNC1_1886
symbol: anmK
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family.


ensembl_gene_id: XNC1_1887
symbol: pdxH
gene_biotype: protein_coding
description:
  Pyridoxine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).


ensembl_gene_id: XNC1_1888
symbol: tyrS
gene_biotype: protein_coding
description:
  Tyrosine tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.


ensembl_gene_id: XNC1_1889
symbol: pdxY
gene_biotype: protein_coding
description:
  Pyridoxal kinase 2/pyridoxine kinase; Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP.


ensembl_gene_id: XNC1_1936
symbol: yebN
gene_biotype: protein_coding
description:
  Putative membrane protein, terpenoid synthase-like; Probably functions as a manganese efflux pump. Belongs to the MntP (TC 9.B.29) family.


ensembl_gene_id: XNC1_1938
symbol: uhpC
gene_biotype: protein_coding
description:
  MFS transporter, OPA family, sugar phosphate sensor protein UhpC; Membrane protein which senses glucose-6-phosphate, interacts with UhpB and UhpA, regulates uhpT expression.


ensembl_gene_id: XNC1_1940
symbol: XNC1_1940
gene_biotype: protein_coding
description:
  Qin prophage; part of two-component toxin-antitoxin system with RelB, transcriptional corepressor of relBE operon (fragment).


ensembl_gene_id: XNC1_1941
symbol: relB
gene_biotype: protein_coding
description:
  Qin prophage; part of two-component toxin-antitoxin system with RelE, transcriptional repressor of relBE operon.


ensembl_gene_id: XNC1_1944
symbol: uhpA
gene_biotype: protein_coding
description:
  Response regulator (activator) in two-component regulatory system wtih UhpB, regulates uhpT expression (LuxR/UhpA family).


ensembl_gene_id: XNC1_1948
symbol: XNC1_1948
gene_biotype: protein_coding
description:
  Putative transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.


ensembl_gene_id: XNC1_1955
symbol: guaB
gene_biotype: protein_coding
description:
  IMP dehydrogeanse; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.


ensembl_gene_id: XNC1_1956
symbol: xseA
gene_biotype: protein_coding
description:
  Exonuclease VII, large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family.


ensembl_gene_id: XNC1_1984
symbol: hspQ
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress; Belongs to the HspQ family.


ensembl_gene_id: XNC1_2022
symbol: XNC1_2022
gene_biotype: protein_coding
description:
  Non Ribosomal peptide synthetase (-succinylbenzoate--CoA ligase); Function of strongly homologous gene; enzyme.


ensembl_gene_id: XNC1_2036
symbol: opaB
gene_biotype: protein_coding
description:
  Attachment invasion locus protein precursor; Function of homologous gene experimentally demonstrated in an other organism; membrane component.


ensembl_gene_id: XNC1_2039
symbol: XNC1_2039
gene_biotype: protein_coding
description:
  Non-ribosomal peptide synthetase (fragment); Belongs to the ATP-dependent AMP-binding enzyme family.


ensembl_gene_id: XNC1_2054
symbol: adhC
gene_biotype: protein_coding
description:
  Alcohol dehydrogenase class III; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.


ensembl_gene_id: XNC1_2056
symbol: hol-1
gene_biotype: protein_coding
description:
  Holin; Function of homologous gene experimentally demonstrated in an other organism; extrachromosomal origin.


ensembl_gene_id: XNC1_2070
symbol: psuG
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway; Belongs to the pseudouridine-5'-phosphate glycosidase family.


ensembl_gene_id: XNC1_2072
symbol: nupX
gene_biotype: protein_coding
description:
  Putative transport protein (NUP family); Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.


ensembl_gene_id: XNC1_2073
symbol: uspG
gene_biotype: protein_coding
description:
  Universal stress protein UP12, flavoprotein, ETFP adenine nucleotide-binding domain; Function of strongly homologous gene; phenotype.


ensembl_gene_id: XNC1_2085
symbol: ydcR
gene_biotype: protein_coding
description:
  Putative bifunctional: transcriptional regulator (GntR family) (N-terminal); amino transferase (C-terminal).


ensembl_gene_id: XNC1_2097
symbol: XNC1_2097
gene_biotype: protein_coding
description:
  Putative deaminase protein with metallo-dependent hydrolase domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: XNC1_2100
symbol: ychF
gene_biotype: protein_coding
description:
  Putative GTP-binding protein with nucleoside triP hydrolase domain; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.


ensembl_gene_id: XNC1_2101
symbol: pth
gene_biotype: protein_coding
description:
  peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.


ensembl_gene_id: XNC1_2104
symbol: estA
gene_biotype: protein_coding
description:
  Phospholipase C/lecithinase, EstA; Function experimentally demonstrated in the studied strain; enzyme.


ensembl_gene_id: XNC1_2107
symbol: prs
gene_biotype: protein_coding
description:
  Phosphoribosylpyrophosphate synthetase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.


ensembl_gene_id: XNC1_2108
symbol: ispE
gene_biotype: protein_coding
description:
  4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol; Belongs to the GHMP kinase family. IspE subfamily.


ensembl_gene_id: XNC1_2109
symbol: lolB
gene_biotype: protein_coding
description:
  Outer membrane component involved in lipoprotein localization; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.


ensembl_gene_id: XNC1_2111
symbol: hemA
gene_biotype: protein_coding
description:
  Glutamyl tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).


ensembl_gene_id: XNC1_2112
symbol: prfA
gene_biotype: protein_coding
description:
  Peptide chain release factor RF-1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.


ensembl_gene_id: XNC1_2113
symbol: prmC
gene_biotype: protein_coding
description:
  N5-glutamine methyltransferase, modifies release factors RF-1 and RF-2; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.


ensembl_gene_id: XNC1_2123
symbol: XNC1_2123
gene_biotype: protein_coding
description:
  Putative Transcriptional regulator, Fis family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.


ensembl_gene_id: XNC1_2126
symbol: XNC1_2126
gene_biotype: protein_coding
description:
  Hypothetical protein (Similarities with unknown protein from a prophage); No homology to any previously reported sequences.


ensembl_gene_id: XNC1_2139
symbol: mviN
gene_biotype: protein_coding
description:
  Putative virulence factor; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.


ensembl_gene_id: XNC1_2142
symbol: cutC
gene_biotype: protein_coding
description:
  Copper homeostasis protein; Participates in the control of copper homeostasis. Belongs to the CutC family.


ensembl_gene_id: XNC1_2143
symbol: yecP
gene_biotype: protein_coding
description:
  Putative methyltransferase with S-adenosyl-L-methionine-dependent methyltransferase domain; Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L- methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5- carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.


ensembl_gene_id: XNC1_2144
symbol: yecO
gene_biotype: protein_coding
description:
  Putative methyltransferase with S-adenosyl-L-methionine-dependent methyltransferase domain; Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).


ensembl_gene_id: XNC1_2146
symbol: aspS
gene_biotype: protein_coding
description:
  Aspartate tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.


ensembl_gene_id: XNC1_2149
symbol: ruvC
gene_biotype: protein_coding
description:
  Holliday junction nuclease; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.


ensembl_gene_id: XNC1_2150
symbol: ruvA
gene_biotype: protein_coding
description:
  Holliday junction helicase, subunit A; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.


ensembl_gene_id: XNC1_2151
symbol: ruvB
gene_biotype: protein_coding
description:
  Holliday junction helicase, subunit B; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.


ensembl_gene_id: XNC1_2156
symbol: XNC1_2156
gene_biotype: protein_coding
description:
  Long-chain-fatty-acid--CoA ligase (polyketide synthase); Function of strongly homologous gene; enzyme.


ensembl_gene_id: XNC1_2157
symbol: XNC1_2157
gene_biotype: protein_coding
description:
  Phenylalanine racemase (ATP-hydrolyzing)(polyketide synthase); Function of strongly homologous gene; enzyme.


ensembl_gene_id: XNC1_2164
symbol: znuC
gene_biotype: protein_coding
description:
  High-affinity Zn transport protein (ABC superfamily, atp_bind); Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family.


ensembl_gene_id: XNC1_2167
symbol: lpxM
gene_biotype: protein_coding
description:
  Myristoyl transferase in lipid A biosynthesis, suppressor of htrB (lpxL); Catalyzes the transfer of myristate from myristoyl-acyl carrier protein (ACP) to Kdo(2)-(lauroyl)-lipid IV(A) to form Kdo(2)- lipid A.


ensembl_gene_id: XNC1_2174
symbol: zwf
gene_biotype: protein_coding
description:
  Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.


ensembl_gene_id: XNC1_2185
symbol: rnd
gene_biotype: protein_coding
description:
  RNase D, processes tRNA precursor; Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides; Belongs to the RNase D family.


ensembl_gene_id: XNC1_2187
symbol: tcdA
gene_biotype: protein_coding
description:
  Partially similar to A component of insecticidal toxin complex (Tc); Function of strongly homologous gene; phenotype.


ensembl_gene_id: XNC1_2190
symbol: minE
gene_biotype: protein_coding
description:
  Cell division topological specificity factor, reverses MinC inhibition of FtsZ ring formation; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.


ensembl_gene_id: XNC1_2192
symbol: minC
gene_biotype: protein_coding
description:
  Cell division inhibitor, inhibits FtsZ ring formation; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family.


ensembl_gene_id: XNC1_2198
symbol: purA-2
gene_biotype: protein_coding
description:
  Adenylosuccinate synthetase 1 (IMP--aspartate ligase 1) (AdSS 1) (AMPSase 1); Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.


ensembl_gene_id: XNC1_2201
symbol: hisA-2
gene_biotype: protein_coding
description:
  1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase 2 (Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase 2).


ensembl_gene_id: XNC1_2204
symbol: ldhA
gene_biotype: protein_coding
description:
  Fermentative D-lactate dehydrogenase, NAD-dependent; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: XNC1_2209
symbol: azoR
gene_biotype: protein_coding
description:
  NADH-azoreductase, FMN-dependent; Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity; Belongs to the azoreductase type 1 family.


ensembl_gene_id: XNC1_2226
symbol: pntA
gene_biotype: protein_coding
description:
  Pyridine nucleotide transhydrogenase (proton pump), alpha subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the AlaDH/PNT family.


ensembl_gene_id: XNC1_2227
symbol: pntB
gene_biotype: protein_coding
description:
  Pyridine nucleotide transhydrogenase (proton pump), beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.


ensembl_gene_id: XNC1_2233
symbol: XNC1_2233
gene_biotype: protein_coding
description:
  Peptide synthetase (Phenylalanine racemase); Function of strongly homologous gene; enzyme; Belongs to the ATP-dependent AMP-binding enzyme family.


ensembl_gene_id: XNC1_2236
symbol: XNC1_2236
gene_biotype: protein_coding
description:
  Glycine amidinotransferase, mitochondrial precursor (L-arginine:glycine amidinotransferase) (Transamidinase) (AT).


ensembl_gene_id: XNC1_2250
symbol: XNC1_2250
gene_biotype: protein_coding
description:
  Putative Extracellular serine protease precursor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.


ensembl_gene_id: XNC1_2263
symbol: XNC1_2263
gene_biotype: protein_coding
description:
  Omega-amino acid--pyruvate aminotransferase (Omega-APT) (Beta-alanine--pyruvate aminotransferase); Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: XNC1_2272
symbol: goaG
gene_biotype: protein_coding
description:
  4-aminobutyrate aminotransferase, PLP-dependent; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: XNC1_2275
symbol: XNC1_2275
gene_biotype: protein_coding
description:
  Putative exported protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.


ensembl_gene_id: XNC1_2299
symbol: XNC1_2299
gene_biotype: protein_coding
description:
  Putative Peptide synthetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: XNC1_2310
symbol: ynfK
gene_biotype: protein_coding
description:
  Putative dethiobiotin synthetase with nucleotide triphosphate hydrolase domain; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. Belongs to the dethiobiotin synthetase family.


ensembl_gene_id: XNC1_2314
symbol: fumC
gene_biotype: protein_coding
description:
  Fumarase C (fumarate hydratase Class II); Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.


ensembl_gene_id: XNC1_2317
symbol: add
gene_biotype: protein_coding
description:
  Adenosine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.


ensembl_gene_id: XNC1_2319
symbol: ydgJ
gene_biotype: protein_coding
description:
  Scyllo-inositol 2-dehydrogenase (NADP+); Putative NAD(P)-binding dehydrogenase, with glyceraldehyde-3-P dehydrogenase-like and NAD(P)-binding domains.


ensembl_gene_id: XNC1_2321
symbol: rsxA
gene_biotype: protein_coding
description:
  Putative oxidoreductase, inner membrane protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.


ensembl_gene_id: XNC1_2322
symbol: rsxB
gene_biotype: protein_coding
description:
  Putative 4Fe-4S ferredoxin-type protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.


ensembl_gene_id: XNC1_2323
symbol: rsxC
gene_biotype: protein_coding
description:
  Putative NADH dehydrogenase subunit/ oxidoreductase; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.


ensembl_gene_id: XNC1_2324
symbol: rsxD
gene_biotype: protein_coding
description:
  Putative oxidoreductase, transmembrane protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the NqrB/RnfD family.


ensembl_gene_id: XNC1_2325
symbol: rnfG
gene_biotype: protein_coding
description:
  Electron transport complex protein rnfG; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the RnfG family.


ensembl_gene_id: XNC1_2326
symbol: rsxE
gene_biotype: protein_coding
description:
  Putative NADH-quinone reductase, membrane protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.


ensembl_gene_id: XNC1_2327
symbol: nth
gene_biotype: protein_coding
description:
  Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.


ensembl_gene_id: XNC1_2333
symbol: tccA
gene_biotype: protein_coding
description:
  A component of insecticidal toxin complex (Tc) (fragment); Function of strongly homologous gene; phenotype.


ensembl_gene_id: XNC1_2404
symbol: rnb
gene_biotype: protein_coding
description:
  RNase II, mRNA degradation; Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction.


ensembl_gene_id: XNC1_2410
symbol: pyrF
gene_biotype: protein_coding
description:
  Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.


ensembl_gene_id: XNC1_2412
symbol: lapB
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane; Belongs to the LapB family.


ensembl_gene_id: XNC1_2413
symbol: lapA
gene_biotype: protein_coding
description:
  Inner membrane protein yciS; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family.


ensembl_gene_id: XNC1_2414
symbol: ribA
gene_biotype: protein_coding
description:
  GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.


ensembl_gene_id: XNC1_2417
symbol: cysB
gene_biotype: protein_coding
description:
  Transcriptional regulator of biosynthesis of L-cysteine and regulator of sulfur assimilation (LysR familiy).


ensembl_gene_id: XNC1_2419
symbol: topA
gene_biotype: protein_coding
description:
  DNA topoisomerase type I, omega protein; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, th [...]


ensembl_gene_id: XNC1_2427
symbol: btuR
gene_biotype: protein_coding
description:
  cob(I)alamin and cobinamide ATP-dependent adenolsyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.


ensembl_gene_id: XNC1_2428
symbol: XNC1_2428
gene_biotype: protein_coding
description:
  Ribosomal large subunit pseudouridine synthase B (rRNA-uridine isomerase B) (rRNA pseudouridylate synthase B); Belongs to the pseudouridine synthase RsuA family.


ensembl_gene_id: XNC1_2433
symbol: trpE
gene_biotype: protein_coding
description:
  Anthranilate synthase component I; Function experimentally demonstrated in the studied strain; enzyme.


ensembl_gene_id: XNC1_2434
symbol: trpG
gene_biotype: protein_coding
description:
  Bifunctional protein:[Includes: para-aminobenzoate synthase glutamine amidotransferase component II (ADC synthase); anthranilate synthase component II ].


ensembl_gene_id: XNC1_2435
symbol: trpD
gene_biotype: protein_coding
description:
  Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).


ensembl_gene_id: XNC1_2436
symbol: trpC
gene_biotype: protein_coding
description:
  Bifunctional: indole-3-glycerolphosphate synthetase (N-terminal); N-(5-phosphoribosyl)anthranilate isomerase (C-terminal); Belongs to the TrpC family.


ensembl_gene_id: XNC1_2437
symbol: trpB
gene_biotype: protein_coding
description:
  Tryptophan synthase, beta protein; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.


ensembl_gene_id: XNC1_2438
symbol: trpA
gene_biotype: protein_coding
description:
  Tryptophan synthase, alpha protein; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.


ensembl_gene_id: XNC1_2443
symbol: yciB
gene_biotype: protein_coding
description:
  Putative membrane protein, intracellular septation protein; Involved in cell division; probably involved in intracellular septation; Belongs to the YciB family.


ensembl_gene_id: XNC1_2449
symbol: tonB
gene_biotype: protein_coding
description:
  Transposase (fragment); Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.


ensembl_gene_id: XNC1_2451
symbol: cls
gene_biotype: protein_coding
description:
  Cardiolipin synthase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.


ensembl_gene_id: XNC1_2459
symbol: XNC1_2459
gene_biotype: protein_coding
description:
  Putative Aculeacin A acylase precursor [Contains: Aculeacin A small subunit; Aculeacin A large subunit].


ensembl_gene_id: XNC1_2470
symbol: XNC1_2470
gene_biotype: protein_coding
description:
  Diaminobutyrate--2-oxoglutarate transaminase; Catalyzes reversively the conversion of L-aspartate beta- semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: XNC1_2474
symbol: oppF
gene_biotype: protein_coding
description:
  Oligopeptide transport protein (ABC superfamily, atp_bind); Function experimentally demonstrated in the studied strain; transporter; Belongs to the ABC transporter superfamily.


ensembl_gene_id: XNC1_2476
symbol: oppC
gene_biotype: protein_coding
description:
  Oligopeptide transport protein (ABC superfamily, membrane); Function experimentally demonstrated in the studied strain; transporter.


ensembl_gene_id: XNC1_2478
symbol: oppA2
gene_biotype: protein_coding
description:
  Oligopeptide transport protein (ABC superfamily, peri_bind); Function experimentally demonstrated in the studied strain; transporter.


ensembl_gene_id: XNC1_2481
symbol: adhE
gene_biotype: protein_coding
description:
  Multifunctional: acetaldehyde-CoA dehydrogenase (N-terminal); iron-dependent alcohol dehydrogenase (C-terminal); pyruvate-formate lyase deactivase.


ensembl_gene_id: XNC1_2482
symbol: XNC1_2482
gene_biotype: protein_coding
description:
  Multifunctional: acetaldehyde-CoA dehydrogenase (N-terminal); iron-dependent alcohol dehydrogenase (C-terminal); pyruvate-formate lyase deactivase (fragment).


ensembl_gene_id: XNC1_2485
symbol: hns
gene_biotype: protein_coding
description:
  Transcriptional regulator, DNA-binding protein HLP-II (HU, BH2, HD, NS), increases DNA thermal stability; Belongs to the histone-like protein H-NS family.


ensembl_gene_id: XNC1_2492
symbol: purU
gene_biotype: protein_coding
description:
  Formyltetrahydrofolate hydrolase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).


ensembl_gene_id: XNC1_2496
symbol: topB
gene_biotype: protein_coding
description:
  DNA topoisomerase III, type 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removin [...]


ensembl_gene_id: XNC1_2510
symbol: gapA
gene_biotype: protein_coding
description:
  Glyceraldehyde-3-phosphate dehydrogenase A; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.


ensembl_gene_id: XNC1_2512
symbol: dadX
gene_biotype: protein_coding
description:
  Alanine racemase 2, PLP-binding, catabolic; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.


ensembl_gene_id: XNC1_2515
symbol: XNC1_2515
gene_biotype: protein_coding
description:
  Conserved hypothetical protein (Vgr family protein, that may be secreted via SST VI system); Homologs of previously reported genes of unknown function.


ensembl_gene_id: XNC1_2516
symbol: XNC1_2516
gene_biotype: protein_coding
description:
  Conserved hypothetical protein (Pentapeptide repeat protein); Homologs of previously reported genes of unknown function.


ensembl_gene_id: XNC1_2517
symbol: XNC1_2517
gene_biotype: protein_coding
description:
  Conserved hypothetical proteins (Pentapeptide repeat protein); Homologs of previously reported genes of unknown function.


ensembl_gene_id: XNC1_2520
symbol: XNC1_2520
gene_biotype: protein_coding
description:
  Conserved Hypothetical protein (putative lipoprotein of SST VI cluster); Homologs of previously reported genes of unknown function.


ensembl_gene_id: XNC1_2521
symbol: XNC1_2521
gene_biotype: protein_coding
description:
  Conserved hypothetical protein, probable component of SST VI cluster; Homologs of previously reported genes of unknown function.


ensembl_gene_id: XNC1_2522
symbol: XNC1_2522
gene_biotype: protein_coding
description:
  Conserved hypothetical protein with OmpA/MotB domains (probable component of SST VI cluster); Homologs of previously reported genes of unknown function.


ensembl_gene_id: XNC1_2523
symbol: XNC1_2523
gene_biotype: protein_coding
description:
  Conserved hypothetical protein (IcmF-like domain protein of SST VI cluster); Homologs of previously reported genes of unknown function.


ensembl_gene_id: XNC1_2524
symbol: XNC1_2524
gene_biotype: protein_coding
description:
  Conserved hypothetical protein (probable component of SST VI); Homologs of previously reported genes of unknown function.


ensembl_gene_id: XNC1_2525
symbol: XNC1_2525
gene_biotype: protein_coding
description:
  Conserved hypothetical protein (probable component of SST VI cluster); Homologs of previously reported genes of unknown function.


ensembl_gene_id: XNC1_2527
symbol: XNC1_2527
gene_biotype: protein_coding
description:
  Putative Type VI secretion system effector (Hcp1 family); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.


ensembl_gene_id: XNC1_2532
symbol: XNC1_2532
gene_biotype: protein_coding
description:
  Putative ClpA/B-type chaperone (Putative ATPase with chaperone activity; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor; Belongs to the ClpA/ClpB family.


ensembl_gene_id: XNC1_2537
symbol: XNC1_2537
gene_biotype: protein_coding
description:
  Conserved hypothetical protein(fragment); Homologs of previously reported genes of unknown function.


ensembl_gene_id: XNC1_2539
symbol: XNC1_2539
gene_biotype: protein_coding
description:
  Putative invasin (fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.


ensembl_gene_id: XNC1_2547
symbol: nhaB
gene_biotype: protein_coding
description:
  Sodium:proton antiporter, regulator of intracellular pH (NhaB family); Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.


ensembl_gene_id: XNC1_2548
symbol: dsbB
gene_biotype: protein_coding
description:
  Disulfide bond formation protein B; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family.


ensembl_gene_id: XNC1_2551
symbol: XNC1_2551
gene_biotype: protein_coding
description:
  Putative ABC-type multidrug transport system (Nickel transport), ATPase component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: XNC1_2559
symbol: XNC1_2559
gene_biotype: protein_coding
description:
  Putative Chitinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: XNC1_2560
symbol: tccA-2
gene_biotype: protein_coding
description:
  A component of insecticidal toxin complex (Tc) (fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; phenotype.


ensembl_gene_id: XNC1_2562
symbol: XNC1_2562
gene_biotype: protein_coding
description:
  Putative chitinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: XNC1_2589
symbol: pgsA
gene_biotype: protein_coding
description:
  CDP-diacylglycerol---glycerol-3-phosphate 3-phosphatidyltransferase; Phosphatidylglycerophosphate synthetase (CDP-1,2-diacyl-sn-glycero-3-phosphate phosphatidyl transferase); Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: XNC1_2590
symbol: uvrC
gene_biotype: protein_coding
description:
  DNA exisiton repair enzyme together with UvrAB; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.


ensembl_gene_id: XNC1_2595
symbol: ada
gene_biotype: protein_coding
description:
  Bifunctional: transcriptional regulator of DNA repair (AraC/Xyl family) (N-terminal); O6-methylguanine-DNA methyltransferase.


ensembl_gene_id: XNC1_2606
symbol: XNC1_2606
gene_biotype: protein_coding
description:
  Putative Sugar fermentation stimulation protein B (Ner-like protein); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.


ensembl_gene_id: XNC1_2613
symbol: ttcA
gene_biotype: protein_coding
description:
  Putative ATPase; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.


ensembl_gene_id: XNC1_2616
symbol: tpx
gene_biotype: protein_coding
description:
  Thiol peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily.


ensembl_gene_id: XNC1_2617
symbol: tyrR
gene_biotype: protein_coding
description:
  Transcriptional regulator of aromatic amino acid biosynthesis and aromatic amino acid transport (EBP family).


ensembl_gene_id: XNC1_2642
symbol: CjrC
gene_biotype: protein_coding
description:
  Putative outer membrane siderophore receptor CjrC; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.


ensembl_gene_id: XNC1_2645
symbol: XNC1_2645
gene_biotype: protein_coding
description:
  Putative protease II (fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: XNC1_2647
symbol: XNC1_2647
gene_biotype: protein_coding
description:
  Putative Oligopeptidase (Fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: XNC1_2651
symbol: maeB
gene_biotype: protein_coding
description:
  Putative bifunctional: malic oxidoreductase (N-terminal); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: XNC1_2652
symbol: narP
gene_biotype: protein_coding
description:
  Two-component system, NarL family, nitrate/nitrite response regulator NarP; Response regulator in two-component regulatory system with NarQ (or NarX), regulates anaerobic respiratory gene expression.


ensembl_gene_id: XNC1_2654
symbol: dapE
gene_biotype: protein_coding
description:
  N-succinyl-diaminopimelate deacylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily.


ensembl_gene_id: XNC1_2657
symbol: ypfI
gene_biotype: protein_coding
description:
  Putative acyl-CoA N-acyltransferase with nucleoside triphosphate hydrolase; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).


ensembl_gene_id: XNC1_2662
symbol: nlpB
gene_biotype: protein_coding
description:
  Lipoprotein-34; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: XNC1_2663
symbol: dapA
gene_biotype: protein_coding
description:
  Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).


ensembl_gene_id: XNC1_2668
symbol: bepA
gene_biotype: protein_coding
description:
  Complete genome; Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.


ensembl_gene_id: XNC1_2672
symbol: upp
gene_biotype: protein_coding
description:
  Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.


ensembl_gene_id: XNC1_2674
symbol: purN
gene_biotype: protein_coding
description:
  Phosphoribosylglycinamide formyltransferase 1; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.


ensembl_gene_id: XNC1_2676
symbol: ppk
gene_biotype: protein_coding
description:
  Polyphosphate kinase, component of RNA degradosome; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family.


ensembl_gene_id: XNC1_2678
symbol: XNC1_2678
gene_biotype: protein_coding
description:
  Putative divalent cation transport protein (divalent cation transporter); Acts as a magnesium transporter.


ensembl_gene_id: XNC1_2681
symbol: mdtA
gene_biotype: protein_coding
description:
  Membrane protein inolved in drug resistance; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: XNC1_2682
symbol: mdtB
gene_biotype: protein_coding
description:
  Multidrug transport protein (RND family); Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtB subfamily.


ensembl_gene_id: XNC1_2683
symbol: mdtC
gene_biotype: protein_coding
description:
  Multidrug transport protein, outer membrane (RND family); Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtC subfamily.


ensembl_gene_id: XNC1_2689
symbol: thiD
gene_biotype: protein_coding
description:
  Bifunctional: hydroxy-methylpyrimidine kinase (HMP kinase); hydroxy-phosphomethylpyrimidine kinase (HMP-P kinase).


ensembl_gene_id: XNC1_2704
symbol: XNC1_2704
gene_biotype: protein_coding
description:
  Ribosomal large subunit pseudouridine synthase E (rRNA-uridine isomerase E) (rRNA pseudouridylate synthase E); Belongs to the pseudouridine synthase RsuA family.


ensembl_gene_id: XNC1_2706
symbol: mnmA
gene_biotype: protein_coding
description:
  tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln), leading to the formation of s(2)U34, the first step of tRNA-mnm(5)s(2)U34 synthesis. Sulfur is provided by IscS, via a sulfur-relay system. Binds ATP and its substrate tRNAs; Belongs to the MnmA/TRMU family.


ensembl_gene_id: XNC1_2709
symbol: phoP
gene_biotype: protein_coding
description:
  Two-component system, OmpR family, response regulator PhoP; Function of homologous gene experimentally demonstrated in an other organism; regulator.


ensembl_gene_id: XNC1_2710
symbol: phoQ
gene_biotype: protein_coding
description:
  Two-component system, OmpR family, sensor histidine kinase PhoQ; Function of homologous gene experimentally demonstrated in an other organism; regulator.


ensembl_gene_id: XNC1_2713
symbol: XNC1_2713
gene_biotype: protein_coding
description:
  Putative Non-ribosomal peptide synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: XNC1_2716
symbol: cobB
gene_biotype: protein_coding
description:
  Putative enzyme with DHS-like NAD/FAD-binding domain; Belongs to the sirtuin family. Class III subfamily.


ensembl_gene_id: XNC1_2719
symbol: lolD
gene_biotype: protein_coding
description:
  Transport protein of outer membrane lipoproteins (ABC superfamily, atp_bind); Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.


ensembl_gene_id: XNC1_2721
symbol: mfd
gene_biotype: protein_coding
description:
  Transcription-repair ATP-dependent coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.


ensembl_gene_id: XNC1_2724
symbol: nagZ
gene_biotype: protein_coding
description:
  Beta N-acetyl-glucosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.


ensembl_gene_id: XNC1_2726
symbol: lpoB
gene_biotype: protein_coding
description:
  Putative fibronectin-binding protein (fragment); Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b).


ensembl_gene_id: XNC1_2730
symbol: tmk
gene_biotype: protein_coding
description:
  Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.


ensembl_gene_id: XNC1_2731
symbol: mltG
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family.


ensembl_gene_id: XNC1_2732
symbol: pabC
gene_biotype: protein_coding
description:
  4-amino-4-deoxychorismate lyase (aminotransferase), component of p-aminobenzoate synthase multienzyme complex.


ensembl_gene_id: XNC1_2733
symbol: fabF
gene_biotype: protein_coding
description:
  3-oxoacyl-[acyl-carrier-protein] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.


ensembl_gene_id: XNC1_2735
symbol: fabG-2
gene_biotype: protein_coding
description:
  3-oxoacyl-[acyl-carrier-protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: XNC1_2737
symbol: fabH
gene_biotype: protein_coding
description:
  3-oxoacyl-[acyl-carrier-protein] synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.


ensembl_gene_id: XNC1_2738
symbol: plsX
gene_biotype: protein_coding
description:
  Fatty acid/phospholipid synthesis protein, methyltransferase domain; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.


ensembl_gene_id: XNC1_2741
symbol: XNC1_2741
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes 7- methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids; Belongs to the Maf family. YceF subfamily.


ensembl_gene_id: XNC1_2742
symbol: rluC
gene_biotype: protein_coding
description:
  23S rRNA pseudouridylate synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.


ensembl_gene_id: XNC1_2743
symbol: rne
gene_biotype: protein_coding
description:
  RNase E: endoribonuclease for rRNA processing and mRNA degradation; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily.


ensembl_gene_id: XNC1_2755
symbol: dld
gene_biotype: protein_coding
description:
  D-lactate dehydrogenase, NADH-independent, FAD-binding domain; Catalyzes the oxidation of D-lactate to pyruvate. Belongs to the quinone-dependent D-lactate dehydrogenase family.


ensembl_gene_id: XNC1_2760
symbol: XNC1_2760
gene_biotype: protein_coding
description:
  Putative FecCD-family membrane transport protein (Inner membrane permease of iron/siderophore ABC transporter); Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: XNC1_2765
symbol: nfo
gene_biotype: protein_coding
description:
  Endonuclease IV, with intrinsic 3'-5' exonuclease activity; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.


ensembl_gene_id: XNC1_2780
symbol: XNC1_2780
gene_biotype: protein_coding
description:
  Putative Type VI secretion protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.


ensembl_gene_id: XNC1_2784
symbol: XNC1_2784
gene_biotype: protein_coding
description:
  Putative ATP-binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.


ensembl_gene_id: XNC1_2801
symbol: pta
gene_biotype: protein_coding
description:
  Phosphotransacetylase (phosphate acetyltransferase); Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.


ensembl_gene_id: XNC1_2802
symbol: ackA
gene_biotype: protein_coding
description:
  Acetate kinase A (propionate kinase 2); Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.


ensembl_gene_id: XNC1_2806
symbol: XNC1_2806
gene_biotype: protein_coding
description:
  Putative alpha helix protein; Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates.


ensembl_gene_id: XNC1_2809
symbol: lrhA
gene_biotype: protein_coding
description:
  Positive transcriptional regulator for motility, lipase activity, toxin and virulence; Function experimentally demonstrated in the studied strain; regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: XNC1_2811
symbol: nuoA
gene_biotype: protein_coding
description:
  NADH dehydrogenase I chain A; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family.


ensembl_gene_id: XNC1_2812
symbol: nuoB
gene_biotype: protein_coding
description:
  NADH dehydrogenase I chain B; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: XNC1_2813
symbol: nuoC
gene_biotype: protein_coding
description:
  NADH dehydrogenase I chain C, D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family.


ensembl_gene_id: XNC1_2815
symbol: nuoF
gene_biotype: protein_coding
description:
  NADH dehydrogenase I chain F; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family.


ensembl_gene_id: XNC1_2816
symbol: nuoG
gene_biotype: protein_coding
description:
  NADH dehydrogenase I chain G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family.


ensembl_gene_id: XNC1_2817
symbol: nuoH
gene_biotype: protein_coding
description:
  NADH dehydrogenase I chain H; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.


ensembl_gene_id: XNC1_2818
symbol: nuoI
gene_biotype: protein_coding
description:
  NADH dehydrogenase I chain I, 2Fe-2S ferredoxin-related; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: XNC1_2819
symbol: nuoJ
gene_biotype: protein_coding
description:
  NADH dehydrogenase I chain J; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: XNC1_2820
symbol: nuoK
gene_biotype: protein_coding
description:
  NADH dehydrogenase I chain K; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family.


ensembl_gene_id: XNC1_2823
symbol: nuoN
gene_biotype: protein_coding
description:
  NADH dehydrogenase I chain N, membrane subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family.


ensembl_gene_id: XNC1_2830
symbol: XNC1_2830
gene_biotype: protein_coding
description:
  Putative lipoprotein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.


ensembl_gene_id: XNC1_2838
symbol: HmsS
gene_biotype: protein_coding
description:
  Haemin storage system (HmsS protein of hmsHFRS Operon); Function experimentally demonstrated in the studied strain; membrane component.


ensembl_gene_id: XNC1_2839
symbol: ycdQ
gene_biotype: protein_coding
description:
  Haemin storage system (HmsS protein of hmsHFRS Operon); Function experimentally demonstrated in the studied strain; factor.


ensembl_gene_id: XNC1_2840
symbol: ycdR
gene_biotype: protein_coding
description:
  Lipoprotein (HmsF protein of hmsHFRS Operon); Function experimentally demonstrated in the studied strain; membrane component.


ensembl_gene_id: XNC1_2842
symbol: menF
gene_biotype: protein_coding
description:
  Isochorismate synthase (isochorismate hydroxymutase 2), menaquinone biosynthesis; Catalyzes the conversion of chorismate to isochorismate.


ensembl_gene_id: XNC1_2845
symbol: menD
gene_biotype: protein_coding
description:
  Bifunctional: 2-oxoglutarate decarboxylase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily.


ensembl_gene_id: XNC1_2846
symbol: yfbB
gene_biotype: protein_coding
description:
  Putative enzyme with alpha/beta-hydrolase domain; Catalyzes a proton abstraction reaction that results in 2,5- elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6- hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).


ensembl_gene_id: XNC1_2847
symbol: menB
gene_biotype: protein_coding
description:
  Dihydroxynaphthoic acid synthetase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA).


ensembl_gene_id: XNC1_2848
symbol: menC
gene_biotype: protein_coding
description:
  o-succinylbenzoyl-CoA synthase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB).


ensembl_gene_id: XNC1_2852
symbol: rcsD
gene_biotype: protein_coding
description:
  Phosphotransferase RcsD; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB.


ensembl_gene_id: XNC1_2853
symbol: rcsB
gene_biotype: protein_coding
description:
  Transcriptional regulatory protein RcsB; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsB is the response regulator that binds to regulatory DNA regions.


ensembl_gene_id: XNC1_2854
symbol: rcsC
gene_biotype: protein_coding
description:
  Sensor histidine kinase RcsC; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane- associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB.


ensembl_gene_id: XNC1_2855
symbol: gyrA
gene_biotype: protein_coding
description:
  DNA gyrase, subunit A, type II topoisomerase; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP- [...]


ensembl_gene_id: XNC1_2856
symbol: ubiG
gene_biotype: protein_coding
description:
  Bifunctional: 3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family.


ensembl_gene_id: XNC1_2857
symbol: nrdA
gene_biotype: protein_coding
description:
  Ribonucleoside diphosphate reductase 1, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.


ensembl_gene_id: XNC1_2876
symbol: vapC
gene_biotype: protein_coding
description:
  PilT protein, N-terminal; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family.


ensembl_gene_id: XNC1_2946
symbol: relE
gene_biotype: protein_coding
description:
  Qin prophage; part of two-component toxin-antitoxin system with RelB, transcriptional corepressor of relBE operon.


ensembl_gene_id: XNC1_2951
symbol: XNC1_2951
gene_biotype: protein_coding
description:
  Probable alginate O-acetylation protein AlgI; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative structure; Belongs to the membrane-bound acyltransferase family.


ensembl_gene_id: XNC1_2972
symbol: yqhA
gene_biotype: protein_coding
description:
  Putative membrane protein; Homologs of previously reported genes of unknown function; putative membrane component.


ensembl_gene_id: XNC1_2975
symbol: XNC1_2975
gene_biotype: protein_coding
description:
  Putative Membrane protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.


ensembl_gene_id: XNC1_2982
symbol: yidK
gene_biotype: protein_coding
description:
  Putative myo-inositol transport protein (SSS family); Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: XNC1_3025
symbol: fbaA
gene_biotype: protein_coding
description:
  A component of insecticidal toxin complex (Tc) (fragment); Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.


ensembl_gene_id: XNC1_3027
symbol: epd
gene_biotype: protein_coding
description:
  D-erythrose 4-phosphate dehydrogenase; Catalyzes the NAD-dependent conversion of D-erythrose 4- phosphate to 4-phosphoerythronate.


ensembl_gene_id: XNC1_3028
symbol: tktA
gene_biotype: protein_coding
description:
  Transketolase 1 thiamin-binding, isozyme; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.


ensembl_gene_id: XNC1_3031
symbol: apbE
gene_biotype: protein_coding
description:
  Putative thiamin biosynthesis lipoprotein; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. Belongs to the ApbE family.


ensembl_gene_id: XNC1_3032
symbol: nqrF
gene_biotype: protein_coding
description:
  Na(+)-translocating NADH-quinone reductase subunit F; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.


ensembl_gene_id: XNC1_3033
symbol: rsxA-2
gene_biotype: protein_coding
description:
  Putative oxidoreductase, inner membrane protein; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol; Belongs to the NqrDE/RnfAE family.


ensembl_gene_id: XNC1_3034
symbol: rsxE-2
gene_biotype: protein_coding
description:
  Putative NADH-quinone reductase, membrane protein; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol; Belongs to the NqrDE/RnfAE family.


ensembl_gene_id: XNC1_3035
symbol: nqrC
gene_biotype: protein_coding
description:
  Na(+)-translocating NADH-quinone reductase subunit C; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.


ensembl_gene_id: XNC1_3036
symbol: nqrB
gene_biotype: protein_coding
description:
  Na(+)-translocating NADH-quinone reductase subunit B; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.


ensembl_gene_id: XNC1_3037
symbol: nqrA
gene_biotype: protein_coding
description:
  Na(+)-translocating NADH-quinone reductase subunit A; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.


ensembl_gene_id: XNC1_3040
symbol: lpcA
gene_biotype: protein_coding
description:
  D-sedoheptulose 7-phosphate isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.


ensembl_gene_id: XNC1_3042
symbol: lysA
gene_biotype: protein_coding
description:
  Diaminopimelate decarboxylase, PLP-binding; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.


ensembl_gene_id: XNC1_3048
symbol: XNC1_3048
gene_biotype: protein_coding
description:
  Bifunctional prepilin peptidase: leader peptidase; methyl transferase (General Secretory Pathway) (fragment); Belongs to the peptidase A24 family.


ensembl_gene_id: XNC1_3049
symbol: XNC1_3049
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.


ensembl_gene_id: XNC1_3105
symbol: yqgF
gene_biotype: protein_coding
description:
  Putative Holliday junction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family.


ensembl_gene_id: XNC1_3109
symbol: yggS
gene_biotype: protein_coding
description:
  Putative enzyme with PLP-binding domain; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.


ensembl_gene_id: XNC1_3110
symbol: proC
gene_biotype: protein_coding
description:
  Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.


ensembl_gene_id: XNC1_3112
symbol: XNC1_3112
gene_biotype: protein_coding
description:
  Putative protein controls HAP (6-N-hydroxylaminopurine) mutagenesis (Ham1); Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.


ensembl_gene_id: XNC1_3113
symbol: yggW
gene_biotype: protein_coding
description:
  Putative oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.


ensembl_gene_id: XNC1_3114
symbol: XNC1_3114
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydratase small subunit (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI); Belongs to the LeuD family.


ensembl_gene_id: XNC1_3125
symbol: yggH
gene_biotype: protein_coding
description:
  tRNA (m7G46) methyltransferase, SAM-dependent; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.


ensembl_gene_id: XNC1_3127
symbol: XNC1_3127
gene_biotype: protein_coding
description:
  Putative Fe(2+) trafficking protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes; Belongs to the Fe(2+)-trafficking protein family.


ensembl_gene_id: XNC1_3128
symbol: mltC
gene_biotype: protein_coding
description:
  Lytic murein transglycosylase C, membrane-bound; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division.


ensembl_gene_id: XNC1_3129
symbol: XNC1_3129
gene_biotype: protein_coding
description:
  Putative phage integrase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme; Belongs to the 'phage' integrase family.


ensembl_gene_id: XNC1_3137
symbol: XNC1_3137
gene_biotype: protein_coding
description:
  Putative integrase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the 'phage' integrase family.


ensembl_gene_id: XNC1_3140
symbol: XNC1_3140
gene_biotype: protein_coding
description:
  Aminoglycoside 3'-N-acetyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: XNC1_3145
symbol: rplY
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family.


ensembl_gene_id: XNC1_3152
symbol: yeiU
gene_biotype: protein_coding
description:
  Putative phosphatase; Involved in the modification of the lipid A domain of lipopolysaccharides (LPS). Transfers a phosphate group from undecaprenyl pyrophosphate (C55-PP) to lipid A to form lipid A 1- diphosphate. Contributes to the recycling of undecaprenyl phosphate (C55-P); Belongs to the LpxT phosphotransferase family.


ensembl_gene_id: XNC1_3157
symbol: yfcG
gene_biotype: protein_coding
description:
  Putative glutathione S-transferase enzyme with thioredoxin-like domain; Belongs to the GST superfamily.


ensembl_gene_id: XNC1_3159
symbol: ubiX
gene_biotype: protein_coding
description:
  3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family.


ensembl_gene_id: XNC1_3160
symbol: purF
gene_biotype: protein_coding
description:
  Amidophosphoribosyltransferase (PRPP amidotransferase); Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.


ensembl_gene_id: XNC1_3162
symbol: dedD
gene_biotype: protein_coding
description:
  Protein dedD; Non-essential cell division protein that could be required for efficient cell constriction.


ensembl_gene_id: XNC1_3163
symbol: folC
gene_biotype: protein_coding
description:
  Bifunctional: folylpolyglutamate synthase; Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10- formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.


ensembl_gene_id: XNC1_3164
symbol: accD
gene_biotype: protein_coding
description:
  acetylCoA carboxylase, carboxyltranferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.


ensembl_gene_id: XNC1_3166
symbol: truA
gene_biotype: protein_coding
description:
  Pseudouridylate synthase I; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.


ensembl_gene_id: XNC1_3167
symbol: usg
gene_biotype: protein_coding
description:
  Putative dehydrogenase with NAD(P)-binding domain and Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain; Belongs to the aspartate-semialdehyde dehydrogenase family.


ensembl_gene_id: XNC1_3168
symbol: pdxB
gene_biotype: protein_coding
description:
  Erythronate-4-phosphate dehydrogenase; Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate.


ensembl_gene_id: XNC1_3174
symbol: fabB
gene_biotype: protein_coding
description:
  3-oxoacyl-[acyl-carrier-protein] synthase I; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: XNC1_3175
symbol: mnmC
gene_biotype: protein_coding
description:
  Putative peptidase; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family.


ensembl_gene_id: XNC1_3183
symbol: aroC
gene_biotype: protein_coding
description:
  Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.


ensembl_gene_id: XNC1_3184
symbol: prmB
gene_biotype: protein_coding
description:
  N5-glutamine methyltransferase, modifies ribosomal protein L3; Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue; Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.


ensembl_gene_id: XNC1_3187
symbol: hutU
gene_biotype: protein_coding
description:
  Urocanate hydratase (Urocanase) (Imidazolonepropionate hydrolase); Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate.


ensembl_gene_id: XNC1_3189
symbol: hutG
gene_biotype: protein_coding
description:
  Formimidoylglutamase (Formiminoglutamase) (Formiminoglutamate hydrolase); Catalyzes the conversion of N-formimidoyl-L-glutamate to L- glutamate and formamide; Belongs to the arginase family.


ensembl_gene_id: XNC1_3194
symbol: fadJ
gene_biotype: protein_coding
description:
  Fatty acid oxidation complex subunit alpha; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities. Belongs to the enoyl-CoA hydratase/isomerase family.  In the central section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.


ensembl_gene_id: XNC1_3195
symbol: fadI
gene_biotype: protein_coding
description:
  Beta-keto thiolase; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.


ensembl_gene_id: XNC1_3205
symbol: gltX
gene_biotype: protein_coding
description:
  Glutamate tRNA synthetase, catalytic subunit; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).


ensembl_gene_id: XNC1_3208
symbol: ligA
gene_biotype: protein_coding
description:
  DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily.


ensembl_gene_id: XNC1_3209
symbol: zipA
gene_biotype: protein_coding
description:
  Cell division protein involved in FtsK recruitment to Z ring; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.


ensembl_gene_id: XNC1_3210
symbol: cysZ
gene_biotype: protein_coding
description:
  Required for sulfate transport; High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway; Belongs to the CysZ family.


ensembl_gene_id: XNC1_3211
symbol: cysK
gene_biotype: protein_coding
description:
  Subunit of cysteine synthase A and O-acetylserine sulfhydrolase A, PLP-dependent enzyme; Belongs to the cysteine synthase/cystathionine beta- synthase family.


ensembl_gene_id: XNC1_3215
symbol: ptsI
gene_biotype: protein_coding
description:
  PTS family enzyme I and Hpr components, PEP-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).


ensembl_gene_id: XNC1_3223
symbol: cysM
gene_biotype: protein_coding
description:
  Cysteine synthase B (O-acetylserine sulfhydrolase B); Belongs to the cysteine synthase/cystathionine beta- synthase family.


ensembl_gene_id: XNC1_3226
symbol: cysA
gene_biotype: protein_coding
description:
  Sulfate permease A protein, chromate resistance (ABC superfamily, atp_bind); Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system.


ensembl_gene_id: XNC1_3228
symbol: cysU
gene_biotype: protein_coding
description:
  Thiosulfate transport protein (ABC superfamily, membrane); Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: XNC1_3244
symbol: smpB
gene_biotype: protein_coding
description:
  Trans-translation protein, binds tmRNA and tRNA; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. Th [...]


ensembl_gene_id: XNC1_3247
symbol: smpA
gene_biotype: protein_coding
description:
  Small membrane protein A; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: XNC1_3248
symbol: recN
gene_biotype: protein_coding
description:
  Protein used in recombination and DNA repair with nucleoside triphosphate hydrolase domain; May be involved in recombinational repair of damaged DNA.


ensembl_gene_id: XNC1_3250
symbol: nadK
gene_biotype: protein_coding
description:
  NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.


ensembl_gene_id: XNC1_3251
symbol: grpE
gene_biotype: protein_coding
description:
  Hsp 24 nucleotide exchange factor; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several roun [...]


ensembl_gene_id: XNC1_3252
symbol: ung
gene_biotype: protein_coding
description:
  uracil-DNA-glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.


ensembl_gene_id: XNC1_3260
symbol: XNC1_3260
gene_biotype: protein_coding
description:
  Colicin-E3 immunity protein (ImmE3) (Microcin-E3 immunity protein) (Colicin-E3 chain B) (modular protein).


ensembl_gene_id: XNC1_3265
symbol: srmB
gene_biotype: protein_coding
description:
  ATP-dependent RNA helicase; DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity; Belongs to the DEAD box helicase family. SrmB subfamily.


ensembl_gene_id: XNC1_3266
symbol: yfiC
gene_biotype: protein_coding
description:
  Putative methyltransferase with S-adenosyl-L-methionine-dependent methyltransferase domain; Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).


ensembl_gene_id: XNC1_3267
symbol: rpoE
gene_biotype: protein_coding
description:
  Sigma E (sigma 24) factor of RNA polymerase, response to periplasmic stress (TetR/ArcR family); Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: XNC1_3268
symbol: rseA
gene_biotype: protein_coding
description:
  Anti sigma E (sigma 24) factor, negative regulator; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytop [...]


ensembl_gene_id: XNC1_3271
symbol: lepA
gene_biotype: protein_coding
description:
  GTP-binding elongation factor; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.


ensembl_gene_id: XNC1_3273
symbol: rnc
gene_biotype: protein_coding
description:
  RNase III, ds RNA; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.


ensembl_gene_id: XNC1_3274
symbol: era
gene_biotype: protein_coding
description:
  GTPase believed to be involved in coordination of cell cycle, energy metabolism, cell division; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.


ensembl_gene_id: XNC1_3275
symbol: recO
gene_biotype: protein_coding
description:
  Gap repair protein, part of RecFOR complex that targets RecA to ssDNA-dsDNA junction; Involved in DNA repair and RecF pathway recombination.


ensembl_gene_id: XNC1_3276
symbol: pdxJ
gene_biotype: protein_coding
description:
  Carries out condensation and ring closure step after PdxA in pyridoxine biosynthesis; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.


ensembl_gene_id: XNC1_3277
symbol: acpS
gene_biotype: protein_coding
description:
  Holo-[acyl-carrier-protein] synthase (CoA:apo-[acyl-carrier-protein] pantetheinephosphotransferase); Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.


ensembl_gene_id: XNC1_3283
symbol: tadA
gene_biotype: protein_coding
description:
  TadA, tRNA-specific adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.


ensembl_gene_id: XNC1_3284
symbol: yfhD
gene_biotype: protein_coding
description:
  Putative protein with periplasmic binding protein domain and lysozyme domain; Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.


ensembl_gene_id: XNC1_3285
symbol: purL
gene_biotype: protein_coding
description:
  Phosphoribosylformyl-glycineamide synthetase (FGAM synthetase); Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.


ensembl_gene_id: XNC1_3289
symbol: nadE
gene_biotype: protein_coding
description:
  Putative glutamine-dependent NAD(+) synthetase (NAD(+) synthase [glutamine-hydrolyzing]) (NadE); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.


ensembl_gene_id: XNC1_3291
symbol: hmp
gene_biotype: protein_coding
description:
  Bifunctional: nitric oxide dioxygenase (N-terminal); Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress; Belongs to the globin family. Two-domain flavohemoproteins subfamily.


ensembl_gene_id: XNC1_3292
symbol: glyA
gene_biotype: protein_coding
description:
  Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.


ensembl_gene_id: XNC1_3296
symbol: yfhQ
gene_biotype: protein_coding
description:
  Putative methyl transferase in Fe-S cluster assembly; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.


ensembl_gene_id: XNC1_3297
symbol: iscR
gene_biotype: protein_coding
description:
  Repressor of the iscRSUA operon, involved in assembly of Fe-S clusters; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.


ensembl_gene_id: XNC1_3298
symbol: iscS
gene_biotype: protein_coding
description:
  Cysteine desulfurase (tRNA sulfurtransferase), PLP-dependent; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.


ensembl_gene_id: XNC1_3299
symbol: iscU
gene_biotype: protein_coding
description:
  Putative Fe-S assembly protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.


ensembl_gene_id: XNC1_3300
symbol: iscA
gene_biotype: protein_coding
description:
  Putative regulator believed to be involved in Fe-S cluster assembly and activation; Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system TrxA/TrxB; Belongs to the HesB/IscA family.


ensembl_gene_id: XNC1_3301
symbol: hscB
gene_biotype: protein_coding
description:
  Co-chaperone protein Hsc20, believed to be involved in assembly of Fe-S clusters; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family.


ensembl_gene_id: XNC1_3302
symbol: hscA
gene_biotype: protein_coding
description:
  Chaperone (Hsp70 family), believed to be involved in assembly of Fe-S clusters; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. Involved in the maturation of IscU.


ensembl_gene_id: XNC1_3303
symbol: fdx
gene_biotype: protein_coding
description:
  [2FE-2S] ferredoxin, electron carrier protein, believed to be involved in assembly of Fe-S clusters.


ensembl_gene_id: XNC1_3305
symbol: pepB
gene_biotype: protein_coding
description:
  Aminopeptidase B, a cysteinylglycinase; Probably plays an important role in intracellular peptide degradation.


ensembl_gene_id: XNC1_3311
symbol: ndk
gene_biotype: protein_coding
description:
  Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.


ensembl_gene_id: XNC1_3313
symbol: yfgB
gene_biotype: protein_coding
description:
  Putative pyruvate formate lyase activating enzyme 2; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family.


ensembl_gene_id: XNC1_3315
symbol: XNC1_3315
gene_biotype: protein_coding
description:
  Putative HTH-type transcriptional regulator yfgA; Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis. Belongs to the RodZ family.


ensembl_gene_id: XNC1_3316
symbol: ispG
gene_biotype: protein_coding
description:
  1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family.


ensembl_gene_id: XNC1_3320
symbol: yfgL
gene_biotype: protein_coding
description:
  Putative serine/threonine protein kinase with quinoprotein alcohol dehydrogenase domain; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: XNC1_3322
symbol: der
gene_biotype: protein_coding
description:
  GTP-binding protein, essential for cell growth; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.


ensembl_gene_id: XNC1_3326
symbol: hemF
gene_biotype: protein_coding
description:
  Coproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX.


ensembl_gene_id: XNC1_3332
symbol: XNC1_3332
gene_biotype: protein_coding
description:
  Putative Na+ driven multidrug efflux pump; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.


ensembl_gene_id: XNC1_3338
symbol: XNC1_3338
gene_biotype: protein_coding
description:
  Putative 3-oxoacyl-[acyl-carrier-protein] synthase; Function of strongly homologous gene; putative enzyme.


ensembl_gene_id: XNC1_3340
symbol: XNC1_3340
gene_biotype: protein_coding
description:
  Putative RNA-binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.


ensembl_gene_id: XNC1_3341
symbol: folD
gene_biotype: protein_coding
description:
  Bifunctional: 5,10-methylene-tetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.


ensembl_gene_id: XNC1_3343
symbol: int
gene_biotype: protein_coding
description:
  Integrase; Function of strongly homologous gene; extrachromosomal origin; Belongs to the 'phage' integrase family.


ensembl_gene_id: XNC1_3348
symbol: XNC1_3348
gene_biotype: protein_coding
description:
  Similar to Rhs-family protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: XNC1_3352
symbol: XNC1_3352
gene_biotype: protein_coding
description:
  Putative DNA-binding prophage protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; extrachromosomal origin.


ensembl_gene_id: XNC1_3355
symbol: XNC1_3355
gene_biotype: protein_coding
description:
  Putatiave helix-turn-helix regulatory protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.


ensembl_gene_id: XNC1_3368
symbol: XNC1_3368
gene_biotype: protein_coding
description:
  Putative transcription regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.


ensembl_gene_id: XNC1_3376
symbol: XNC1_3376
gene_biotype: protein_coding
description:
  Putative Mu-like prophage FluMu protein gp27; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: XNC1_3377
symbol: XNC1_3377
gene_biotype: protein_coding
description:
  Putative Mu-like prophage FluMu protein gp28; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: XNC1_3378
symbol: XNC1_3378
gene_biotype: protein_coding
description:
  Mu-like prophage FluMu protein gp29; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: XNC1_3382
symbol: XNC1_3382
gene_biotype: protein_coding
description:
  Putative protease protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.


ensembl_gene_id: XNC1_3383
symbol: XNC1_3383
gene_biotype: protein_coding
description:
  Putative major head subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative structure.


ensembl_gene_id: XNC1_3388
symbol: XNC1_3388
gene_biotype: protein_coding
description:
  Putative tail sheath protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative structure.


ensembl_gene_id: XNC1_3389
symbol: XNC1_3389
gene_biotype: protein_coding
description:
  Putative tail tube protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative structure.


ensembl_gene_id: XNC1_3390
symbol: XNC1_3390
gene_biotype: protein_coding
description:
  Putative prophage protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: XNC1_3393
symbol: XNC1_3393
gene_biotype: protein_coding
description:
  Putative DNA circulation protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.


ensembl_gene_id: XNC1_3394
symbol: XNC1_3394
gene_biotype: protein_coding
description:
  Putative tail protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; carrier.


ensembl_gene_id: XNC1_3395
symbol: XNC1_3395
gene_biotype: protein_coding
description:
  Putative baseplate assembly protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: XNC1_3396
symbol: XNC1_3396
gene_biotype: protein_coding
description:
  Putative bacteriophage protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: XNC1_3406
symbol: sfsB-3
gene_biotype: protein_coding
description:
  Sugar fermentation stimulation protein B (Ner-like protein); Function of strongly homologous gene; regulator.


ensembl_gene_id: XNC1_3407
symbol: XNC1_3407
gene_biotype: protein_coding
description:
  Putative membrane protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: XNC1_3414
symbol: XNC1_3414
gene_biotype: protein_coding
description:
  Putative antitermination protein Q; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.


ensembl_gene_id: XNC1_3417
symbol: XNC1_3417
gene_biotype: protein_coding
description:
  Putative DNA methylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the N(4)/N(6)-methyltransferase family.


ensembl_gene_id: XNC1_3418
symbol: XNC1_3418
gene_biotype: protein_coding
description:
  Putative proteic killer active protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.


ensembl_gene_id: XNC1_3424
symbol: XNC1_3424
gene_biotype: protein_coding
description:
  Putative sugar fermentation stimulation protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.


ensembl_gene_id: XNC1_3425
symbol: XNC1_3425
gene_biotype: protein_coding
description:
  Putative terminase large subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: XNC1_3426
symbol: XNC1_3426
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: XNC1_3427
symbol: XNC1_3427
gene_biotype: protein_coding
description:
  Putative holin protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.


ensembl_gene_id: XNC1_3429
symbol: XNC1_3429
gene_biotype: protein_coding
description:
  Putative head-tail adaptor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: XNC1_3430
symbol: XNC1_3430
gene_biotype: protein_coding
description:
  Putative head portal protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative structure.


ensembl_gene_id: XNC1_3431
symbol: XNC1_3431
gene_biotype: protein_coding
description:
  Putative prohead protease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: XNC1_3432
symbol: XNC1_3432
gene_biotype: protein_coding
description:
  Putative major capsid protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative structure.


ensembl_gene_id: XNC1_3435
symbol: XNC1_3435
gene_biotype: protein_coding
description:
  Putative haemolysin co-regulated protein (hcp-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative structure.


ensembl_gene_id: XNC1_3438
symbol: XNC1_3438
gene_biotype: protein_coding
description:
  Putative phage primase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: XNC1_3442
symbol: XNC1_3442
gene_biotype: protein_coding
description:
  Putative phage-related protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: XNC1_3443
symbol: intB-2
gene_biotype: protein_coding
description:
  Integrase (bacteriophage integrase); Function of strongly homologous gene; putative enzyme; Belongs to the 'phage' integrase family.


ensembl_gene_id: XNC1_3450
symbol: XNC1_3450
gene_biotype: protein_coding
description:
  DNA topoisomerase III; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: XNC1_3453
symbol: ssb
gene_biotype: protein_coding
description:
  Single-stranded DNA-binding protein; Function of homologous gene experimentally demonstrated in an other organism; factor.


ensembl_gene_id: XNC1_3457
symbol: insB
gene_biotype: protein_coding
description:
  Insertion element IS1; Function of homologous gene experimentally demonstrated in an other organism; extrachromosomal origin.


ensembl_gene_id: XNC1_3460
symbol: XNC1_3460
gene_biotype: protein_coding
description:
  Transposase; Function of homologous gene experimentally demonstrated in an other organism; extrachromosomal origin.


ensembl_gene_id: XNC1_3469
symbol: XNC1_3469
gene_biotype: protein_coding
description:
  Rhs family protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: XNC1_3470
symbol: XNC1_3470
gene_biotype: protein_coding
description:
  Putative exported protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: XNC1_3481
symbol: XNC1_3481
gene_biotype: protein_coding
description:
  Putative transposase (fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; extrachromosomal origin.


ensembl_gene_id: XNC1_3491
symbol: XNC1_3491
gene_biotype: protein_coding
description:
  Putative carbamoyltransferase protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: XNC1_3493
symbol: nodQ
gene_biotype: protein_coding
description:
  Putative bifunctional enzyme: sulfate adenylyltransferase and Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.


ensembl_gene_id: XNC1_3501
symbol: XNC1_3501
gene_biotype: protein_coding
description:
  Putative toxin-antitoxin protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; 16738553.


ensembl_gene_id: XNC1_3506
symbol: XNC1_3506
gene_biotype: protein_coding
description:
  Putative phage integrase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; extrachromosomal origin; Belongs to the 'phage' integrase family.


ensembl_gene_id: XNC1_3507
symbol: sfsB-4
gene_biotype: protein_coding
description:
  Sugar fermentation stimulation protein B (Ner-like protein); Function of homologous gene experimentally demonstrated in an other organism; regulator.


ensembl_gene_id: XNC1_3513
symbol: XNC1_3513
gene_biotype: protein_coding
description:
  Putative IS element; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; extrachromosomal origin.


ensembl_gene_id: XNC1_3522
symbol: sfsB-5
gene_biotype: protein_coding
description:
  Sugar fermentation stimulation protein (Ner-like protein) (fragment); Function of strongly homologous gene; putative regulator.


ensembl_gene_id: XNC1_3526
symbol: XNC1_3526
gene_biotype: protein_coding
description:
  Putative integrase protein (fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; extrachromosomal origin.


ensembl_gene_id: XNC1_3529
symbol: XNC1_3529
gene_biotype: protein_coding
description:
  Putative chromosome partitioning related protein SOJ-like protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: XNC1_3531
symbol: dnaB
gene_biotype: protein_coding
description:
  Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily.


ensembl_gene_id: XNC1_3545
symbol: XNC1_3545
gene_biotype: protein_coding
description:
  Putative pilL protein (fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: XNC1_3548
symbol: XNC1_3548
gene_biotype: protein_coding
description:
  Putative plasmid transfer protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: XNC1_3561
symbol: XNC1_3561
gene_biotype: protein_coding
description:
  Putative lipoprotein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: XNC1_3564
symbol: XNC1_3564
gene_biotype: protein_coding
description:
  Putative TpsA-related protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.


ensembl_gene_id: XNC1_3569
symbol: XNC1_3569
gene_biotype: protein_coding
description:
  Putative Rhs family protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: XNC1_3571
symbol: XNC1_3571
gene_biotype: protein_coding
description:
  Putative VrgG protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: XNC1_3578
symbol: aroA-2
gene_biotype: protein_coding
description:
  3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.


ensembl_gene_id: XNC1_3581
symbol: XNC1_3581
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the TPP enzyme family.


ensembl_gene_id: XNC1_3582
symbol: XNC1_3582
gene_biotype: protein_coding
description:
  Putative drug resistance transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: XNC1_3592
symbol: XNC1_3592
gene_biotype: protein_coding
description:
  Putative antirestriction protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; 8393008.


ensembl_gene_id: XNC1_3594
symbol: XNC1_3594
gene_biotype: protein_coding
description:
  Putative toxin-antitoxin system protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.


ensembl_gene_id: XNC1_3598
symbol: XNC1_3598
gene_biotype: protein_coding
description:
  Putative phage integrase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the 'phage' integrase family.


ensembl_gene_id: XNC1_3599
symbol: yjdC
gene_biotype: protein_coding
description:
  Putative regulator with homeodomain-like DNA binding domain with homeodomain-like DNA binding domain (TetR/AcrR family).


ensembl_gene_id: XNC1_3600
symbol: dipZ
gene_biotype: protein_coding
description:
  Thiol:disulfide interchange protein DsbD; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily.


ensembl_gene_id: XNC1_3601
symbol: dcuA
gene_biotype: protein_coding
description:
  Anaerobic dicarboxylate transport protein (Dcu family); Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane; Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.


ensembl_gene_id: XNC1_3604
symbol: groS
gene_biotype: protein_coding
description:
  Chaperone Hsp10 (GroES), part of GroE chaperone system; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.


ensembl_gene_id: XNC1_3611
symbol: efp
gene_biotype: protein_coding
description:
  Elongation factor P (EF-P); Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation; Belongs to the elongation factor P family.


ensembl_gene_id: XNC1_3622
symbol: rsmC
gene_biotype: protein_coding
description:
  16S RNA m2G1207 methylase; Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle; Belongs to the methyltransferase superfamily. RsmC family.


ensembl_gene_id: XNC1_3623
symbol: holD
gene_biotype: protein_coding
description:
  DNA polymerase III, psi subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown.


ensembl_gene_id: XNC1_3643
symbol: XNC1_3643
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Homologs of previously reported genes of unknown function; 15271940.


ensembl_gene_id: XNC1_3669
symbol: vsr
gene_biotype: protein_coding
description:
  DNA mismatch endonuclease, patch repair protein; May nick specific sequences that contain T:G mispairs resulting from m5C-deamination.


ensembl_gene_id: XNC1_3686
symbol: XNC1_3686
gene_biotype: protein_coding
description:
  Putative TpsA-related protein(fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.


ensembl_gene_id: XNC1_3689
symbol: XNC1_3689
gene_biotype: protein_coding
description:
  Putative TpsA-related protein (fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.


ensembl_gene_id: XNC1_3701
symbol: potD
gene_biotype: protein_coding
description:
  Spermidine/putrescine transport protein (ABC superfamily, peri_bind); Required for the activity of the bacterial periplasmic transport system of putrescine; Belongs to the bacterial solute-binding protein PotD/PotF family.


ensembl_gene_id: XNC1_3705
symbol: potA
gene_biotype: protein_coding
description:
  Spermidine/putrescine transport protein (ABC superfamily, atp_bind); Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.


ensembl_gene_id: XNC1_3707
symbol: gloB
gene_biotype: protein_coding
description:
  Putative hydroxyacylglutathione hydrolase with metallo-hydrolase/oxidoreductase domain; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.


ensembl_gene_id: XNC1_3709
symbol: rnhA
gene_biotype: protein_coding
description:
  RNase HI, degrades RNA of DNA-RNA hybrids; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.


ensembl_gene_id: XNC1_3710
symbol: dnaQ
gene_biotype: protein_coding
description:
  DNA polymerase III: epsilon subunit, 3-5 exonucleolytic proofreading function; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.


ensembl_gene_id: XNC1_3717
symbol: XNC1_3717
gene_biotype: protein_coding
description:
  Conserved hypothetical protein (Similar to unknown protein YgcB of Escherichia coli); Homologs of previously reported genes of unknown function.


ensembl_gene_id: XNC1_3718
symbol: XNC1_3718
gene_biotype: protein_coding
description:
  Conserved hypothetical protein (Similar to unknown protein YgcL of Escherichia coli); Homologs of previously reported genes of unknown function.


ensembl_gene_id: XNC1_3720
symbol: XNC1_3720
gene_biotype: protein_coding
description:
  Conserved hypothetical protein (Similar to unknown protein YgcJ of Escherichia coli); Homologs of previously reported genes of unknown function.


ensembl_gene_id: XNC1_3721
symbol: XNC1_3721
gene_biotype: protein_coding
description:
  Conserved hypothetical protein (similar to protein ygcI precursor of E. coli); Homologs of previously reported genes of unknown function.


ensembl_gene_id: XNC1_3722
symbol: XNC1_3722
gene_biotype: protein_coding
description:
  Conserved hypothetical protein (Similar to unknown protein YgcH of Escherichia coli); Homologs of previously reported genes of unknown function.


ensembl_gene_id: XNC1_3723
symbol: cas1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein (Uncharacterized protein ygbT); CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.


ensembl_gene_id: XNC1_3724
symbol: XNC1_3724
gene_biotype: protein_coding
description:
  Conserved hypothetical protein (similar to protein ygbF of E. coli); Homologs of previously reported genes of unknown function.


ensembl_gene_id: XNC1_3734
symbol: XNC1_3734
gene_biotype: protein_coding
description:
  Conserved hypothetical protein (Similar to photopexin A/B of Photorhabdus luminescens); Homologs of previously reported genes of unknown function.


ensembl_gene_id: XNC1_3735
symbol: pagC
gene_biotype: protein_coding
description:
  Virulence membrane protein pagC precursor; Function of homologous gene experimentally demonstrated in an other organism; membrane component.


ensembl_gene_id: XNC1_3739
symbol: fecI
gene_biotype: protein_coding
description:
  Probable RNA polymerase sigma factor fecI; Function of strongly homologous gene; regulator; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: XNC1_3740
symbol: fecR
gene_biotype: protein_coding
description:
  Protein fecR; Function of homologous gene experimentally demonstrated in an other organism; regulator.


ensembl_gene_id: XNC1_3741
symbol: fecA
gene_biotype: protein_coding
description:
  Iron(III) dicitrate transport protein fecA; Function of homologous gene experimentally demonstrated in an other organism; transporter.


ensembl_gene_id: XNC1_3742
symbol: fecB
gene_biotype: protein_coding
description:
  Iron(III) dicitrate-binding periplasmic protein precursor FecB; Function of homologous gene experimentally demonstrated in an other organism; carrier.


ensembl_gene_id: XNC1_3743
symbol: fecC
gene_biotype: protein_coding
description:
  Iron(III) dicitrate transport system permease protein fecC; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: XNC1_3744
symbol: fecD
gene_biotype: protein_coding
description:
  Iron(III) dicitrate transport system permease protein fecD; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: XNC1_3745
symbol: fecE
gene_biotype: protein_coding
description:
  Iron(III) dicitrate transport ATP-binding protein fecE; Function of homologous gene experimentally demonstrated in an other organism; transporter.


ensembl_gene_id: XNC1_3756
symbol: radA
gene_biotype: protein_coding
description:
  DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.


ensembl_gene_id: XNC1_3771
symbol: XNC1_3771
gene_biotype: protein_coding
description:
  Putative CdcB-like protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; factor.


ensembl_gene_id: XNC1_3774
symbol: opnS
gene_biotype: protein_coding
description:
  Growth-phase-regulated outer membrane protein OpnS; Function experimentally demonstrated in the studied strain; transporter.


ensembl_gene_id: XNC1_3775
symbol: rdgC
gene_biotype: protein_coding
description:
  Putative ribonuclease involved in removal of stalled replication fork with Rh-like domain; May be involved in recombination; Belongs to the RdgC family.


ensembl_gene_id: XNC1_3783
symbol: nhaA
gene_biotype: protein_coding
description:
  Sodium:proton antiporter (NhaA family); Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.


ensembl_gene_id: XNC1_3784
symbol: nhaR
gene_biotype: protein_coding
description:
  Transcriptional activator of cation transport (LysR family); Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: XNC1_3787
symbol: ileS
gene_biotype: protein_coding
description:
  Isoleucine tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.


ensembl_gene_id: XNC1_3788
symbol: lspA
gene_biotype: protein_coding
description:
  Prolipoprotein signal peptidase (SPase II); This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.


ensembl_gene_id: XNC1_3790
symbol: ispH
gene_biotype: protein_coding
description:
  1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate reductase, 4Fe-4S protein; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.


ensembl_gene_id: XNC1_3793
symbol: XNC1_3793
gene_biotype: protein_coding
description:
  Alanyl-tRNA synthetase-related protein (fragment); Gene remnant; enzyme; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: XNC1_3794
symbol: dapB
gene_biotype: protein_coding
description:
  Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.


ensembl_gene_id: XNC1_3795
symbol: carA
gene_biotype: protein_coding
description:
  Carbamoyl phosphate synthetase, glutamine amidotransferase small subunit; Belongs to the CarA family.


ensembl_gene_id: XNC1_3797
symbol: mrxJ
gene_biotype: protein_coding
description:
  Repressor of flagellae, MrxJ; Function of homologous gene experimentally demonstrated in an other organism; regulator.


ensembl_gene_id: XNC1_3800
symbol: mrxD
gene_biotype: protein_coding
description:
  Periplasmic fimbrial chaperone precursor, MrxD; Function experimentally demonstrated in the studied strain; structure.


ensembl_gene_id: XNC1_3801
symbol: mrxC
gene_biotype: protein_coding
description:
  Outer membrane usher protein, MrxC; Function experimentally demonstrated in the studied strain; structure.


ensembl_gene_id: XNC1_3803
symbol: mrxA
gene_biotype: protein_coding
description:
  Major fimbrial subunit polypeptide, MrfA; Function experimentally demonstrated in the studied strain; structure.


ensembl_gene_id: XNC1_3806
symbol: deoB
gene_biotype: protein_coding
description:
  Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family.


ensembl_gene_id: XNC1_3807
symbol: deoA
gene_biotype: protein_coding
description:
  Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.


ensembl_gene_id: XNC1_3808
symbol: deoC
gene_biotype: protein_coding
description:
  2-deoxyribose-5-phosphate aldolase, NAD(P)-linked; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily.


ensembl_gene_id: XNC1_3813
symbol: prfC
gene_biotype: protein_coding
description:
  Putative peptide chain release factor RF-3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.


ensembl_gene_id: XNC1_3828
symbol: XNC1_3828
gene_biotype: protein_coding
description:
  Putative lipase/esterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: XNC1_3838
symbol: XNC1_3838
gene_biotype: protein_coding
description:
  Protein of unknown function (similar to YjiA of E. coli); Homologs of previously reported genes of unknown function; phenotype.


ensembl_gene_id: XNC1_3841
symbol: XNC1_3841
gene_biotype: protein_coding
description:
  Restriction modification system DNA specificity domain:Filamentation induced by cAMP protein Fic (fragment).


ensembl_gene_id: XNC1_3843
symbol: mutS
gene_biotype: protein_coding
description:
  Methyl-directed mismatch repair, recognizes exocyclic adducts of guanosine; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.


ensembl_gene_id: XNC1_3846
symbol: rpoS
gene_biotype: protein_coding
description:
  tRNA-(ms[2]io[6]A)-hydroxylase (fragment); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.


ensembl_gene_id: XNC1_3848
symbol: pcm
gene_biotype: protein_coding
description:
  L-isoaspartate protein carboxylmethyltransferase type II; Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.


ensembl_gene_id: XNC1_3849
symbol: surE
gene_biotype: protein_coding
description:
  Survival protein, protein damage control; Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP. Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20-25). Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs.


ensembl_gene_id: XNC1_3850
symbol: truD
gene_biotype: protein_coding
description:
  Putative hydrogenase subunit; Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family.


ensembl_gene_id: XNC1_3851
symbol: ispF
gene_biotype: protein_coding
description:
  2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).


ensembl_gene_id: XNC1_3852
symbol: ispD
gene_biotype: protein_coding
description:
  4-diphosphocytidyl-2C-methyl-D-erythritol synthase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.


ensembl_gene_id: XNC1_3855
symbol: cysN
gene_biotype: protein_coding
description:
  ATP-sulfurylase, subunit 1 (ATP:sulfate adenylyltransferase); May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.


ensembl_gene_id: XNC1_3857
symbol: cysG
gene_biotype: protein_coding
description:
  Multifunctional siroheme synthase: uroporphyrinogen methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family.  In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.


ensembl_gene_id: XNC1_3858
symbol: cysH
gene_biotype: protein_coding
description:
  3'-phosphoadenosine 5'-phosphosulfate (PAPS) reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.


ensembl_gene_id: XNC1_3859
symbol: cysI
gene_biotype: protein_coding
description:
  Sulfite reductase, beta subunit, NADPH-dependent hemoprotein; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.


ensembl_gene_id: XNC1_3860
symbol: cysJ
gene_biotype: protein_coding
description:
  Sulfite reductase, alpha subunit (flavoprotein); Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component. Belongs to the NADPH-dependent sulphite reductase flavoprotein subunit CysJ family. In the N-terminal section; belongs to the flavodoxin family.


ensembl_gene_id: XNC1_3862
symbol: ygcF
gene_biotype: protein_coding
description:
  Putative coenzyme PQQ synthesis protein with nitrogenase iron-molybdenum domain; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.


ensembl_gene_id: XNC1_3872
symbol: trkH
gene_biotype: protein_coding
description:
  Potassium transport protein, requires TrkE (Trk family); Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA; Belongs to the TrkH potassium transport family.


ensembl_gene_id: XNC1_3875
symbol: fadB
gene_biotype: protein_coding
description:
  Enoyl-CoA hydratase/Delta(3)-cis-Delta(2)-trans-enoyl-CoA isomerase/3-hydroxybutyryl-CoA epimerase; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: XNC1_3876
symbol: fadA
gene_biotype: protein_coding
description:
  3-ketoacyl-CoA thiolase; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.


ensembl_gene_id: XNC1_3878
symbol: ubiD
gene_biotype: protein_coding
description:
  3-octaprenyl-4-hydroxybenzoate decarboxylase; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.


ensembl_gene_id: XNC1_3879
symbol: rfaH
gene_biotype: protein_coding
description:
  Transcription antitermination protein RfaH; Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components. RfaH is recruited into a multi-component RNA polymerase complex by the ops element, which is a short conserved DNA sequence located downstream of the main promoter of these operons. Once bound, RfaH suppresses pausing and inhibits Rho-dependent and intrinsic termination at a subset of sites. Termination signals are bypassed, which allows complete synthesis of long RNA chains.


ensembl_gene_id: XNC1_3881
symbol: tatC
gene_biotype: protein_coding
description:
  Twin-arginine translocase subunit, sec-independent protein export; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.


ensembl_gene_id: XNC1_3882
symbol: tatB
gene_biotype: protein_coding
description:
  Sec-independent protein translocase protein TatB; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.


ensembl_gene_id: XNC1_3883
symbol: tatA
gene_biotype: protein_coding
description:
  Twin-arginine translocase subunit, sec-independent protein export; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.


ensembl_gene_id: XNC1_3884
symbol: ubiB
gene_biotype: protein_coding
description:
  2-octaprenylphenol hydroxylase of ubiquinone biosynthetic pathway; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.


ensembl_gene_id: XNC1_3886
symbol: ubiE
gene_biotype: protein_coding
description:
  Bifunctional: 2-octaprenyl-6-methoxy-1,4-benzoquinone methylase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2).


ensembl_gene_id: XNC1_3889
symbol: udp
gene_biotype: protein_coding
description:
  Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family.


ensembl_gene_id: XNC1_3892
symbol: metE
gene_biotype: protein_coding
description:
  5-methyltetrahydropteroyltriglutamate- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.


ensembl_gene_id: XNC1_3895
symbol: yjcE
gene_biotype: protein_coding
description:
  Putative sodium:hydrogen antiporter (CPA1 family); Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.


ensembl_gene_id: XNC1_3898
symbol: XNC1_3898
gene_biotype: protein_coding
description:
  Putative Acy-homoserine lactone acylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: XNC1_3901
symbol: XNC1_3901
gene_biotype: protein_coding
description:
  Colicin-E2 immunity protein (ImmE2) (Microcin-E2 immunity protein); Function of strongly homologous gene; phenotype.


ensembl_gene_id: XNC1_3902
symbol: XNC1_3902
gene_biotype: protein_coding
description:
  Putative permease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.


ensembl_gene_id: XNC1_3903
symbol: XNC1_3903
gene_biotype: protein_coding
description:
  Efflux pump component MtrF (antibiotic resistance); Function of strongly homologous gene; membrane component.


ensembl_gene_id: XNC1_3907
symbol: nirB
gene_biotype: protein_coding
description:
  Nitrite reductase, large subunit, nucleotide-binding; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.


ensembl_gene_id: XNC1_3910
symbol: XNC1_3910
gene_biotype: protein_coding
description:
  Beta-ketoacyl synthase; Function of strongly homologous gene; enzyme; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: XNC1_3912
symbol: XNC1_3912
gene_biotype: protein_coding
description:
  Putative transcriptional regulator (Cro/CI family); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.


ensembl_gene_id: XNC1_3914
symbol: ssb-4
gene_biotype: protein_coding
description:
  ssDNA-binding protein controls activity of RecBCD nuclease; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.


ensembl_gene_id: XNC1_3915
symbol: uvrA
gene_biotype: protein_coding
description:
  DNA excision repair enzyme subunit, with UvrBC; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.


ensembl_gene_id: XNC1_3919
symbol: alr
gene_biotype: protein_coding
description:
  Alanine racemase 1, PLP-binding, biosynthetic; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.


ensembl_gene_id: XNC1_3927
symbol: dusA
gene_biotype: protein_coding
description:
  tRNA-dihydrouridine synthase A; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily.


ensembl_gene_id: XNC1_3935
symbol: lexA
gene_biotype: protein_coding
description:
  Transcriptional repressor for SOS response (signal peptidase of LexA family); Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'. In the presence of single- stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.


ensembl_gene_id: XNC1_3936
symbol: dgkA
gene_biotype: protein_coding
description:
  Diacylglycerol kinase; Recycling of diacylglycerol produced during the turnover of membrane phospholipid.


ensembl_gene_id: XNC1_3938
symbol: ubiA
gene_biotype: protein_coding
description:
  P-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.


ensembl_gene_id: XNC1_3939
symbol: ubiC
gene_biotype: protein_coding
description:
  Chorismate pyruvate lyase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.


ensembl_gene_id: XNC1_3946
symbol: eda
gene_biotype: protein_coding
description:
  Multifunctional: 2-keto-3-deoxygluconate 6-phosphate aldolase; 2-keto-4-hydroxyglutarate aldolase; oxaloacetate decarboxylase.


ensembl_gene_id: XNC1_3948
symbol: aceK
gene_biotype: protein_coding
description:
  Isocitrate dehydrogenase kinase/phosphatase; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.


ensembl_gene_id: XNC1_3973
symbol: metA
gene_biotype: protein_coding
description:
  Homoserine transsuccinylase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine; Belongs to the MetA family.


ensembl_gene_id: XNC1_3979
symbol: metN
gene_biotype: protein_coding
description:
  D-and L-methionine transport protein (ABC superfamily, atp_bind); Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.


ensembl_gene_id: XNC1_3981
symbol: metQ
gene_biotype: protein_coding
description:
  D-methionine transport protein (ABC superfamily, peri_bind); Belongs to the nlpA lipoprotein family.


ensembl_gene_id: XNC1_3983
symbol: rcsF
gene_biotype: protein_coding
description:
  Regulator in colanic acid synthesis; Essential component of the Rcs signaling system, which controls transcription of numerous genes. Plays a role in signal transduction from the cell surface to the histidine kinase RcsC. May detect outer membrane defects; Belongs to the RcsF family.


ensembl_gene_id: XNC1_3985
symbol: proS
gene_biotype: protein_coding
description:
  Proline tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves de [...]


ensembl_gene_id: XNC1_3988
symbol: tilS
gene_biotype: protein_coding
description:
  TilS, tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.


ensembl_gene_id: XNC1_3990
symbol: accA-2
gene_biotype: protein_coding
description:
  acetylCoA carboxylase, carboxytransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.


ensembl_gene_id: XNC1_3993
symbol: lpxB
gene_biotype: protein_coding
description:
  tetraacyldisaccharide-1-P synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: XNC1_3994
symbol: lpxA
gene_biotype: protein_coding
description:
  UDP-N-acetylglucosamine acetyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: XNC1_3995
symbol: fabZ
gene_biotype: protein_coding
description:
  (3R)-hydroxymyristol acyl carrier protein dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.


ensembl_gene_id: XNC1_3996
symbol: lpxD
gene_biotype: protein_coding
description:
  UDP-3-O-(3-hydroxymyristoyl)-glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O- (hydroxytetradecanoyl)glucosamine using 3-hydroxytetradecanoyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell; Belongs to the transferase hexapeptide repeat family. LpxD subfamily.


ensembl_gene_id: XNC1_3998
symbol: ecfK
gene_biotype: protein_coding
description:
  Putative outer membrane antigen; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamD, the core component of the assembly machinery.


ensembl_gene_id: XNC1_4001
symbol: ispU
gene_biotype: protein_coding
description:
  Undecaprenyl pyrophosphate synthetase (di-trans,poly-cis-decaprenylcistransferase); Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.


ensembl_gene_id: XNC1_4003
symbol: dxr
gene_biotype: protein_coding
description:
  1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP).


ensembl_gene_id: XNC1_4004
symbol: frr
gene_biotype: protein_coding
description:
  Ribosome releasing factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.


ensembl_gene_id: XNC1_4006
symbol: tsf
gene_biotype: protein_coding
description:
  Protein chain elongation factor EF-Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.


ensembl_gene_id: XNC1_4008
symbol: map
gene_biotype: protein_coding
description:
  Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.


ensembl_gene_id: XNC1_4009
symbol: glnD
gene_biotype: protein_coding
description:
  Uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.


ensembl_gene_id: XNC1_4010
symbol: dapD
gene_biotype: protein_coding
description:
  2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family.


ensembl_gene_id: XNC1_4017
symbol: syd
gene_biotype: protein_coding
description:
  Interacts with secY; Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function. Belongs to the Syd family.


ensembl_gene_id: XNC1_4019
symbol: queF
gene_biotype: protein_coding
description:
  7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).


ensembl_gene_id: XNC1_4020
symbol: xni
gene_biotype: protein_coding
description:
  Exonuclease IX, 5'-3' exonuclease; Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.


ensembl_gene_id: XNC1_4026
symbol: ygdE
gene_biotype: protein_coding
description:
  Putative RNA 2'-O-ribose methyltransferase, SAM-dependent domain; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.


ensembl_gene_id: XNC1_4028
symbol: gcvA
gene_biotype: protein_coding
description:
  Transcriptional regulator (postitive) of cleavage of glycine (LysR family); Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: XNC1_4032
symbol: mltA
gene_biotype: protein_coding
description:
  Membrane-bound lytic murein transglycosylase A; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division.


ensembl_gene_id: XNC1_4034
symbol: argA
gene_biotype: protein_coding
description:
  N-alpha-acetylglutamate synthase (amino-acid acetyltransferase); Belongs to the acetyltransferase family. ArgA subfamily.


ensembl_gene_id: XNC1_4035
symbol: recD
gene_biotype: protein_coding
description:
  Exonuclease V, alpha chain with recC and recD: 5' and 3' nuclease, ATPase, recombinase, helicase; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA- [...]


ensembl_gene_id: XNC1_4036
symbol: recB
gene_biotype: protein_coding
description:
  Exonuclease V, beta chain with recC and recD: 5' and 3' nuclease, ATPase, recombinase, helicase; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-b [...]


ensembl_gene_id: XNC1_4038
symbol: recC
gene_biotype: protein_coding
description:
  Exonuclease V, gamma chain with recB and recD: 5' and 3' nuclease, ATPase, recombinase, helicase; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA- [...]


ensembl_gene_id: XNC1_4048
symbol: thyA
gene_biotype: protein_coding
description:
  Thymidylate synthetase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.


ensembl_gene_id: XNC1_4049
symbol: lgt
gene_biotype: protein_coding
description:
  Phosphatidylglycerol-prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.


ensembl_gene_id: XNC1_4051
symbol: ptsP
gene_biotype: protein_coding
description:
  PTS family enzyme I, transcriptional regulator (with NPR and NTR proteins); Belongs to the PEP-utilizing enzyme family.


ensembl_gene_id: XNC1_4052
symbol: nudH
gene_biotype: protein_coding
description:
  Nucleotide hydrolase, acts on adenosine(5')-pentaphospho-(5')-adenosine (Nudix family); Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily.


ensembl_gene_id: XNC1_4055
symbol: thiQ
gene_biotype: protein_coding
description:
  Thiamin transport protein (ABC superfamily, atp_bind); Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Thiamine importer (TC 3.A.1.19.1) family.


ensembl_gene_id: XNC1_4059
symbol: hepA
gene_biotype: protein_coding
description:
  ATPase associated with RNA polymerase and transcriptional activator; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily.


ensembl_gene_id: XNC1_4060
symbol: rluA
gene_biotype: protein_coding
description:
  23S rRNA pseudouridylate 746 synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.


ensembl_gene_id: XNC1_4061
symbol: djlA
gene_biotype: protein_coding
description:
  Co-chaperone of DnbaK (DnaJ-like), implicated in regulation of colanic acid capsule; Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.


ensembl_gene_id: XNC1_4062
symbol: imp
gene_biotype: protein_coding
description:
  Organic solvent tolerance; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.


ensembl_gene_id: XNC1_4063
symbol: surA
gene_biotype: protein_coding
description:
  Peptidyl-prolyl cis-trans isomerase (PPIase), involved in maturation of outer membrane proteins; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.


ensembl_gene_id: XNC1_4064
symbol: pdxA
gene_biotype: protein_coding
description:
  4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).


ensembl_gene_id: XNC1_4065
symbol: ksgA
gene_biotype: protein_coding
description:
  S-adenosylmethionine-6-N',N'-adenosyl (rRNA) dimethyltransferase, kasugamycin resistance; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.


ensembl_gene_id: XNC1_4067
symbol: apaH
gene_biotype: protein_coding
description:
  Diadenosine tetraphosphatase; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family.


ensembl_gene_id: XNC1_4068
symbol: folA
gene_biotype: protein_coding
description:
  Dihydrofolate reductase type I, trimethoprim resistance; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.


ensembl_gene_id: XNC1_4070
symbol: sufI
gene_biotype: protein_coding
description:
  Repressor protein for FtsI with three cupredoxin-like domains; Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress.


ensembl_gene_id: XNC1_4071
symbol: plsC
gene_biotype: protein_coding
description:
  1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.


ensembl_gene_id: XNC1_4072
symbol: parC
gene_biotype: protein_coding
description:
  DNA topoisomerase IV, subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.


ensembl_gene_id: XNC1_4073
symbol: parE
gene_biotype: protein_coding
description:
  DNA topoisomerase IV, subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily.


ensembl_gene_id: XNC1_4075
symbol: cpdA
gene_biotype: protein_coding
description:
  Cyclic 3',5'-adenosine monophosphate phosphodiesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.


ensembl_gene_id: XNC1_4077
symbol: tolC
gene_biotype: protein_coding
description:
  Outer membrane channel; tolerance to colicin E1, segregation of daughter chromosomes, role in organic solvent tolerance.


ensembl_gene_id: XNC1_4082
symbol: ribB
gene_biotype: protein_coding
description:
  3,4 dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.


ensembl_gene_id: XNC1_4084
symbol: rfaE
gene_biotype: protein_coding
description:
  Putative bifunctional ADP-L-glycero-D-manno-heptose synthase: putaive kinase (N-terminal); Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family.


ensembl_gene_id: XNC1_4085
symbol: glnE
gene_biotype: protein_coding
description:
  Adenylyl transferase for glutamine synthetase, regulates P-II (GlnB) and GlnK; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory regio [...]


ensembl_gene_id: XNC1_4088
symbol: cca
gene_biotype: protein_coding
description:
  tRNA nucleotidyl transferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 2 subfamily.


ensembl_gene_id: XNC1_4089
symbol: folB
gene_biotype: protein_coding
description:
  Dihydroneopterin aldolase, also has dihydroneopterin triphosphate 2'-epimerase activity; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.


ensembl_gene_id: XNC1_4090
symbol: ygiH
gene_biotype: protein_coding
description:
  Putative membrane protein; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.


ensembl_gene_id: XNC1_4092
symbol: ygjD
gene_biotype: protein_coding
description:
  Putative O-sialoglycoprotein endopeptidase, with actin-like ATPase domain; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.


ensembl_gene_id: XNC1_4094
symbol: dnaG
gene_biotype: protein_coding
description:
  DNA biosynthesis; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.


ensembl_gene_id: XNC1_4095
symbol: rpoD
gene_biotype: protein_coding
description:
  Sigma D (sigma 70) factor of RNA polymerase; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.


ensembl_gene_id: XNC1_4098
symbol: sfsB-7
gene_biotype: protein_coding
description:
  Sugar fermentation stimulation protein B (Ner-like protein); Function of homologous gene experimentally demonstrated in an other organism; phenotype.


ensembl_gene_id: XNC1_4113
symbol: XNC1_4113
gene_biotype: protein_coding
description:
  Putative phage primase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.


ensembl_gene_id: XNC1_4146
symbol: sstT
gene_biotype: protein_coding
description:
  Na+:serine/threonine symporter (DAACS family); Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system). Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: XNC1_4156
symbol: yraL
gene_biotype: protein_coding
description:
  Putative enzyme with Cobalt precorrin-4 methyltransferase domain; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.


ensembl_gene_id: XNC1_4163
symbol: mtgA
gene_biotype: protein_coding
description:
  Peptidoglycan transglycosylase, biosynthetic; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family.


ensembl_gene_id: XNC1_4164
symbol: elbB
gene_biotype: protein_coding
description:
  Glyoxalase; Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate; Belongs to the peptidase C56 family.


ensembl_gene_id: XNC1_4165
symbol: arcB
gene_biotype: protein_coding
description:
  Aerobic respiration control sensor protein; Hybrid sensory histidine kinase in two-component regulatory system with ArcA, regulates respiration and fermentation, senses oxidized quinones.


ensembl_gene_id: XNC1_4176
symbol: rplM
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.


ensembl_gene_id: XNC1_4177
symbol: yhcM
gene_biotype: protein_coding
description:
  Putative ATPase, with nucleoside triP hydrolase domain; Reduces the stability of FtsZ polymers in the presence of ATP.


ensembl_gene_id: XNC1_4183
symbol: murA
gene_biotype: protein_coding
description:
  UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.


ensembl_gene_id: XNC1_4192
symbol: kdsC
gene_biotype: protein_coding
description:
  3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, KDO biosynthesis (E. coli B strain); Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family.


ensembl_gene_id: XNC1_4193
symbol: lptC
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family.


ensembl_gene_id: XNC1_4194
symbol: yhbN
gene_biotype: protein_coding
description:
  Putative transport protein (ABC superfamily, peri_bind); Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.


ensembl_gene_id: XNC1_4196
symbol: rpoN
gene_biotype: protein_coding
description:
  Sigma N (sigma 54) factor of RNA polymerase; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.


ensembl_gene_id: XNC1_4200
symbol: rapZ
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ. When glucosamine-6- phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E. Consequently, GlmZ is inactivated and unable to activate GlmS synthesis. Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS; Belongs to the RapZ-like family. RapZ subfamily.


ensembl_gene_id: XNC1_4202
symbol: cynS
gene_biotype: protein_coding
description:
  Cyanate aminohydrolase (cyanase); Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide; Belongs to the cyanase family.


ensembl_gene_id: XNC1_4203
symbol: cynR
gene_biotype: protein_coding
description:
  Cyn operon positive regulator (LysR family); Function of homologous gene experimentally demonstrated in an other organism; regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: XNC1_4208
symbol: XNC1_4208
gene_biotype: protein_coding
description:
  Putative alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.


ensembl_gene_id: XNC1_4209
symbol: rnk
gene_biotype: protein_coding
description:
  Regulator of nucleoside diphosphate kinase; May act as an anti-Gre factor; Belongs to the Rnk family.


ensembl_gene_id: XNC1_4213
symbol: pmbA
gene_biotype: protein_coding
description:
  Protein pmbA; Function of homologous gene experimentally demonstrated in an other organism; putative enzyme.


ensembl_gene_id: XNC1_4214
symbol: yjgA
gene_biotype: protein_coding
description:
  Putative transport protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the UPF0307 family.


ensembl_gene_id: XNC1_4228
symbol: XNC1_4228
gene_biotype: protein_coding
description:
  Putative aspartate racemase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the aspartate/glutamate racemases family.


ensembl_gene_id: XNC1_4229
symbol: XNC1_4229
gene_biotype: protein_coding
description:
  Putative LysR-family transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: XNC1_4230
symbol: XNC1_4230
gene_biotype: protein_coding
description:
  Putative glutamate symport transmembrane protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: XNC1_4238
symbol: XNC1_4238
gene_biotype: protein_coding
description:
  Putative transport protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative carrier.


ensembl_gene_id: XNC1_4239
symbol: XNC1_4239
gene_biotype: protein_coding
description:
  Putative phosphoribosylglycinamide formyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.


ensembl_gene_id: XNC1_4250
symbol: XNC1_4250
gene_biotype: protein_coding
description:
  Putative phage-related protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; extrachromosomal origin.


ensembl_gene_id: XNC1_4257
symbol: pepA
gene_biotype: protein_coding
description:
  Aminopeptidase A, a cyteinylglycinase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.


ensembl_gene_id: XNC1_4259
symbol: valS
gene_biotype: protein_coding
description:
  Valine tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.


ensembl_gene_id: XNC1_4282
symbol: XNC1_4282
gene_biotype: protein_coding
description:
  Putative 4-aminobutyrate aminotransferase, PLP-dependent; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: XNC1_4283
symbol: malT
gene_biotype: protein_coding
description:
  HTH-type transcriptional regulator MalT; Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto- oligosaccharides. Specifically binds to the promoter region of its target genes, recognizing a short DNA motif called the MalT box.


ensembl_gene_id: XNC1_4285
symbol: malP
gene_biotype: protein_coding
description:
  Maltodextrin phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.


ensembl_gene_id: XNC1_4289
symbol: malE
gene_biotype: protein_coding
description:
  Maltose transport protein, chemotaxis (ABC superfamily, peri_bind); Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Binds maltose and higher maltodextrins. Belongs to the bacterial solute-binding protein 1 family.


ensembl_gene_id: XNC1_4290
symbol: malK
gene_biotype: protein_coding
description:
  Bifunctional: maltose transport protein (ABC superfamily, atp_bind) (N-terminal); Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Maltooligosaccharide importer (TC 3.A.1.1.1) family.


ensembl_gene_id: XNC1_4323
symbol: ydeV
gene_biotype: protein_coding
description:
  Putative sugar kinase, actin-like ATPase domain; Catalyzes the phosphorylation of autoinducer-2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of (S)-4,5-dihydroxypentane-2,3-dione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position.


ensembl_gene_id: XNC1_4324
symbol: XNC1_4324
gene_biotype: protein_coding
description:
  Putative sugar transport protein with periplasmic binding protein domain (ABC superfamily, peri_bind) (fragment).


ensembl_gene_id: XNC1_4325
symbol: lsrF
gene_biotype: protein_coding
description:
  Putative aldolase with ribulose-phoshate binding barrel; Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the transfer of an acetyl moiety from 3-hydroxy-5- phosphonooxypentane-2,4-dione to CoA to form glycerone phosphate and acetyl-CoA; Belongs to the DeoC/FbaB aldolase family.


ensembl_gene_id: XNC1_4326
symbol: lsrG
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the conversion of (4S)-4-hydroxy-5- phosphonooxypentane-2,3-dione (P-DPD) to 3-hydroxy-5- phosphonooxypentane-2,4-dione (P-HPD); Belongs to the LsrG family.


ensembl_gene_id: XNC1_4328
symbol: mobA
gene_biotype: protein_coding
description:
  Molybdopterin-guanine dinucleotide synthase; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family.


ensembl_gene_id: XNC1_4329
symbol: srkA
gene_biotype: protein_coding
description:
  Protein rdoA; A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.


ensembl_gene_id: XNC1_4331
symbol: polA
gene_biotype: protein_coding
description:
  Multifunctional DNA polymerase I: 5'->3' exonuclease (N-terminal); In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.


ensembl_gene_id: XNC1_4332
symbol: yihA
gene_biotype: protein_coding
description:
  Putative GTPase with nucleoside triP hydrolase domain, involved in coordination of cell cycle; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.


ensembl_gene_id: XNC1_4334
symbol: ppiA
gene_biotype: protein_coding
description:
  Peptidyl-prolyl cis-trans isomerase A (rotamase A); PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.


ensembl_gene_id: XNC1_4335
symbol: pabA
gene_biotype: protein_coding
description:
  Aminodeoxychorismate synthase subunit II, component of p-aminobenzoate synthase multienzyme complex; Function experimentally demonstrated in the studied strain; enzyme.


ensembl_gene_id: XNC1_4336
symbol: argD
gene_biotype: protein_coding
description:
  Acetylornithine transaminase (NAcOATase and DapATase), PLP-dependent; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.


ensembl_gene_id: XNC1_4344
symbol: murQ
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.


ensembl_gene_id: XNC1_4349
symbol: kefG
gene_biotype: protein_coding
description:
  Putative electron transfer flavoprotein-NAD/FAD/quinone oxidoreductase; Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefB.


ensembl_gene_id: XNC1_4350
symbol: kefB
gene_biotype: protein_coding
description:
  Potassium:proton antiporter (CPA2 family); Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport.


ensembl_gene_id: XNC1_4366
symbol: tusD
gene_biotype: protein_coding
description:
  Putative intracellular sulfur oxidation protein; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE.


ensembl_gene_id: XNC1_4367
symbol: tusC
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.


ensembl_gene_id: XNC1_4369
symbol: rpsL
gene_biotype: protein_coding
description:
  30S ribosomal subunit protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.


ensembl_gene_id: XNC1_4370
symbol: rpsG
gene_biotype: protein_coding
description:
  30S ribosomal subunit protein S7, initiates assembly; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.


ensembl_gene_id: XNC1_4371
symbol: fusA
gene_biotype: protein_coding
description:
  Protein chain elongation factor EF-G, GTP-binding; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase f [...]


ensembl_gene_id: XNC1_4373
symbol: secE
gene_biotype: protein_coding
description:
  Protein translocase subunit SecE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61-gamma family.


ensembl_gene_id: XNC1_4374
symbol: nusG
gene_biotype: protein_coding
description:
  Component in transcription antitermination; Participates in transcription elongation, termination and antitermination. In the absence of Rho, increases the rate of transcription elongation by the RNA polymerase (RNAP), probably by partially suppressing pausing. In the presence of Rho, modulates most Rho-dependent termination events by interacting with the RNAP to render the complex more susceptible to the termination activity of Rho. May be required to overcome a kinetic limitation of Rho to function at certain terminators. Also involved in ribosomal RNA transcriptional antitermination [...]


ensembl_gene_id: XNC1_4375
symbol: rplK
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L11, N-terminal believed to regulate RelA; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.


ensembl_gene_id: XNC1_4376
symbol: rplA
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L1, regulates synthesis of L1 and L11; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.


ensembl_gene_id: XNC1_4377
symbol: rplJ
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.


ensembl_gene_id: XNC1_4378
symbol: rplL
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family.


ensembl_gene_id: XNC1_4379
symbol: rpoB
gene_biotype: protein_coding
description:
  RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: XNC1_4380
symbol: rpoC
gene_biotype: protein_coding
description:
  RNA polymerase, beta prime subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: XNC1_4381
symbol: XNC1_4381
gene_biotype: protein_coding
description:
  Putative xylanase/chitin deacetylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: XNC1_4392
symbol: XNC1_4392
gene_biotype: protein_coding
description:
  Putative DNA-binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: XNC1_4410
symbol: glnL
gene_biotype: protein_coding
description:
  Sensory kinase (soluble) in two-component regulatory system with GlnG, nitrogen regulation (nitrogen regulator II, NRII).


ensembl_gene_id: XNC1_4411
symbol: glnG
gene_biotype: protein_coding
description:
  Response regulator in two-component regulatory system with GlnL, nitrogen regulation (EBP family); Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.


ensembl_gene_id: XNC1_4412
symbol: XNC1_4412
gene_biotype: protein_coding
description:
  Potassium-transporting ATPase A chain (Potassium-translocating ATPase A chain) (ATP phosphohydrolase [potassium-transporting] A chain) (Potassium binding and translocating subunit A) (fragment).


ensembl_gene_id: XNC1_4415
symbol: hemN
gene_biotype: protein_coding
description:
  Coproporphyrinogen III oxidase, O2-independent, SAM and NAD(P)H dependent; Belongs to the anaerobic coproporphyrinogen-III oxidase family.


ensembl_gene_id: XNC1_4416
symbol: yihI
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis. Belongs to the YihI family.


ensembl_gene_id: XNC1_4425
symbol: XNC1_4425
gene_biotype: protein_coding
description:
  Putative Hcp-like protein of Escherichia coli; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.


ensembl_gene_id: XNC1_4428
symbol: XNC1_4428
gene_biotype: protein_coding
description:
  Putative amino acid-binding protein (ABC superfamily, peri_bind); Belongs to the bacterial solute-binding protein 3 family.


ensembl_gene_id: XNC1_4429
symbol: phoU
gene_biotype: protein_coding
description:
  Transcriptional repressor for high-affinity phosphate uptake; Part of the phosphate (Pho) regulon, which plays a key role in phosphate homeostasis. PhoU is essential for the repression of the Pho regulon at high phosphate conditions.


ensembl_gene_id: XNC1_4430
symbol: pstB
gene_biotype: protein_coding
description:
  High-affinity phosphate transport protein (ABC superfamily, atp_bind); Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.


ensembl_gene_id: XNC1_4432
symbol: pstC
gene_biotype: protein_coding
description:
  High-affinity phosphate transport protein (ABC superfamily, membrane); Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: XNC1_4434
symbol: pstS
gene_biotype: protein_coding
description:
  High-affinity phosphate transport protein (ABC superfamily, peri_bind); Part of the ABC transporter complex PstSACB involved in phosphate import; Belongs to the PstS family.


ensembl_gene_id: XNC1_4436
symbol: ompR
gene_biotype: protein_coding
description:
  Response regulator in two-component regulatory system with EnvZ, regulates ompF and ompC expression (OmpR family).


ensembl_gene_id: XNC1_4437
symbol: greB
gene_biotype: protein_coding
description:
  Transcription elongation factor and transcript cleavage; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.


ensembl_gene_id: XNC1_4443
symbol: feoB
gene_biotype: protein_coding
description:
  Ferrous iron transport protein B (FeoB family); Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.


ensembl_gene_id: XNC1_4444
symbol: yhgG
gene_biotype: protein_coding
description:
  Putative transcriptional regulator with DNA-binding Winged helix domain; May function as a transcriptional regulator that controls feoABC expression.


ensembl_gene_id: XNC1_4450
symbol: yhiQ
gene_biotype: protein_coding
description:
  Putative methyltransferase with SAM-dependent methyltransferase domain; Specifically methylates the guanosine in position 1516 of 16S rRNA.


ensembl_gene_id: XNC1_4469
symbol: glpD
gene_biotype: protein_coding
description:
  Sn-glycerol-3-phosphate dehydrogenase FAD/NAD(P)-binding (aerobic); Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.


ensembl_gene_id: XNC1_4473
symbol: glpG
gene_biotype: protein_coding
description:
  Putative membrane protein, member of glp regulon; Rhomboid-type serine protease that catalyzes intramembrane proteolysis.


ensembl_gene_id: XNC1_4474
symbol: glpE
gene_biotype: protein_coding
description:
  Thiosulfate:cyanide sulfurtransferase (rhodanese); Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.


ensembl_gene_id: XNC1_4476
symbol: nfuA
gene_biotype: protein_coding
description:
  Fe/S biogenesis protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.


ensembl_gene_id: XNC1_4478
symbol: bioH
gene_biotype: protein_coding
description:
  Putative enzyme in pimeloyl-CoA (biotin precursor) synthesis with alpha/beta-hydrolase domain; The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.


ensembl_gene_id: XNC1_4490
symbol: dppF
gene_biotype: protein_coding
description:
  Dipeptide transport protein (ABC superfamily, atp_bind); Belongs to the ABC transporter superfamily.


ensembl_gene_id: XNC1_4505
symbol: XNC1_4505
gene_biotype: protein_coding
description:
  Colicin V secretion/processing ATP-binding protein cvaB; Function of strongly homologous gene; enzyme.


ensembl_gene_id: XNC1_4509
symbol: ligB
gene_biotype: protein_coding
description:
  DNA ligase; Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. Belongs to the NAD-dependent DNA ligase family. LigB subfamily.


ensembl_gene_id: XNC1_4511
symbol: rpoZ
gene_biotype: protein_coding
description:
  RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.


ensembl_gene_id: XNC1_4512
symbol: spoT
gene_biotype: protein_coding
description:
  Bifunctional: (p)ppGpp synthetase II; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.


ensembl_gene_id: XNC1_4513
symbol: trmH
gene_biotype: protein_coding
description:
  Putative tRNA/rRNA methyltransferase; Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.


ensembl_gene_id: XNC1_4514
symbol: recG
gene_biotype: protein_coding
description:
  DNA helicase, ATP-dependent resolution of Holliday junctions, branch migration; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily.


ensembl_gene_id: XNC1_4515
symbol: gltS
gene_biotype: protein_coding
description:
  Glutamate transport protein (GltS family); Catalyzes the sodium-dependent transport of glutamate. Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.


ensembl_gene_id: XNC1_4520
symbol: dtd
gene_biotype: protein_coding
description:
  D-Tyr-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family.


ensembl_gene_id: XNC1_4538
symbol: XNC1_4538
gene_biotype: protein_coding
description:
  Conserved Hypothetical protein with ImpA domain (probable component of SST VI cluster); Homologs of previously reported genes of unknown function.


ensembl_gene_id: XNC1_4540
symbol: XNC1_4540
gene_biotype: protein_coding
description:
  Conserved hypothetical protein with ImpA domain(probable component of SST VI cluster); Homologs of previously reported genes of unknown function.


ensembl_gene_id: XNC1_4542
symbol: XNC1_4542
gene_biotype: protein_coding
description:
  Conserved Hypothetical protein (probable component of SSt VI cluster); Homologs of previously reported genes of unknown function.


ensembl_gene_id: XNC1_4547
symbol: XNC1_4547
gene_biotype: protein_coding
description:
  Conserved hypothetical protein (probable lipoprotein of SST VI cluster); Homologs of previously reported genes of unknown function.


ensembl_gene_id: XNC1_4548
symbol: XNC1_4548
gene_biotype: protein_coding
description:
  Conserved hypothetical protein with FHA domain (probable component of SST VI cluster); Homologs of previously reported genes of unknown function.


ensembl_gene_id: XNC1_4549
symbol: XNC1_4549
gene_biotype: protein_coding
description:
  Conserved hypothetical protein (probable component of the SST VI cluster); Homologs of previously reported genes of unknown function.


ensembl_gene_id: XNC1_4551
symbol: XNC1_4551
gene_biotype: protein_coding
description:
  Conserved hypothetical protein (probable component of the SST VI cluster; Homologs of previously reported genes of unknown function.


ensembl_gene_id: XNC1_4554
symbol: hcp
gene_biotype: protein_coding
description:
  Hemolysin-coregulated protein Hcp(probable Type VI secreted cytotoxin system component); Homologs of previously reported genes of unknown function.


ensembl_gene_id: XNC1_4555
symbol: xhlB
gene_biotype: protein_coding
description:
  XhlB, XhlA hemolysin secretion/activation protein (TpsB); Function of homologous gene experimentally demonstrated in an other organism; transporter.


ensembl_gene_id: XNC1_4556
symbol: xhlA
gene_biotype: protein_coding
description:
  XhlA, Cell surface associated hemolysin (TpsA); Function experimentally demonstrated in the studied strain; factor.


ensembl_gene_id: XNC1_4560
symbol: XNC1_4560
gene_biotype: protein_coding
description:
  Putative Type VI secretion system Vgr family protein (fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.


ensembl_gene_id: XNC1_4561
symbol: XNC1_4561
gene_biotype: protein_coding
description:
  Putative Transposase (fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: XNC1_4573
symbol: XNC1_4573
gene_biotype: protein_coding
description:
  Putative Reverse transcriptase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: XNC1_4592
symbol: nudE
gene_biotype: protein_coding
description:
  ADP-ribose diphosphatase; Nudix hydrolase, active on adenosine(5')triphospho(5')adenosine, adenosine(5')diphospho(5')adenosine, ADP-ribose and NADH.


ensembl_gene_id: XNC1_4595
symbol: hslO
gene_biotype: protein_coding
description:
  Heat shock protein 33, redox regulated chaperone; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.


ensembl_gene_id: XNC1_4596
symbol: pck
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.


ensembl_gene_id: XNC1_4600
symbol: XNC1_4600
gene_biotype: protein_coding
description:
  Putative AMP-dependent synthetase/ligase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: XNC1_4616
symbol: paaA
gene_biotype: protein_coding
description:
  Ring-1,2-phenylacetyl-CoA epoxidase subunit PaaA; Putative subunit of multicomponent oxygenase, phenylacetic acid degradation with ferritin-like domain.


ensembl_gene_id: XNC1_4620
symbol: paaE
gene_biotype: protein_coding
description:
  Ring-1,2-phenylacetyl-CoA epoxidase subunit PaaE; Putative phenylacetic acid degradation protein with NADP-linked, 2Fe-2S ferredoxin-like and riboflavin synthase-like domains.


ensembl_gene_id: XNC1_4621
symbol: paaF
gene_biotype: protein_coding
description:
  enoyl-CoA hydratase-isomerase, phenylacetic acid degradation (strain W); Belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: XNC1_4624
symbol: XNC1_4624
gene_biotype: protein_coding
description:
  Acyl-CoA thioesterase; Putative phenylacetic acid degradation protein with thioesterase/thiol ester dehydrase-isomerase domain (modular protein).


ensembl_gene_id: XNC1_4626
symbol: paaJ
gene_biotype: protein_coding
description:
  Putative beta-ketoadipyl CoA thiolase with thiolase-like domain, phenylacetic acid degradation; Belongs to the thiolase-like superfamily. Thiolase family.


ensembl_gene_id: XNC1_4627
symbol: paaK
gene_biotype: protein_coding
description:
  phenylacetyl-CoA ligase, phenylacetic acid degradation; Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).


ensembl_gene_id: XNC1_4632
symbol: XNC1_4632
gene_biotype: protein_coding
description:
  Conserved hypothetical protein (with PilT protein domain); Homologs of previously reported genes of unknown function.


ensembl_gene_id: XNC1_4642
symbol: mnmE
gene_biotype: protein_coding
description:
  GTPase involved in tRNA modification and in thiophene and furan oxidation; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.


ensembl_gene_id: XNC1_4643
symbol: yidC
gene_biotype: protein_coding
description:
  Preprotein translocase, cooperates with SecYEG and SecDFyajC translocon, membrane component; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.


ensembl_gene_id: XNC1_4644
symbol: XNC1_4644
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family.


ensembl_gene_id: XNC1_4645
symbol: rnpA
gene_biotype: protein_coding
description:
  RNase P, protein C5 component, processes tRNA, 4.5S RNA; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.


