# geneInfo

ensembl_gene_id: Ssed_0001
symbol: mnmE
gene_biotype: protein_coding
description:
  tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.


ensembl_gene_id: Ssed_0002
symbol: yidC
gene_biotype: protein_coding
description:
  60 kDa inner membrane insertion protein; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.


ensembl_gene_id: Ssed_0003
symbol: Ssed_0003
gene_biotype: protein_coding
description:
  Protein of unknown function DUF37; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family.


ensembl_gene_id: Ssed_0004
symbol: rnpA
gene_biotype: protein_coding
description:
  Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.


ensembl_gene_id: Ssed_0005
symbol: rpmH
gene_biotype: protein_coding
description:
  KEGG: shw:Sputw3181_4095 ribosomal protein L34; Belongs to the bacterial ribosomal protein bL34 family.


ensembl_gene_id: Ssed_0006
symbol: dnaA
gene_biotype: protein_coding
description:
  Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.


ensembl_gene_id: Ssed_0007
symbol: Ssed_0007
gene_biotype: protein_coding
description:
  DNA-directed DNA polymerase; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of repl [...]


ensembl_gene_id: Ssed_0008
symbol: recF
gene_biotype: protein_coding
description:
  DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.


ensembl_gene_id: Ssed_0009
symbol: gyrB
gene_biotype: protein_coding
description:
  DNA topoisomerase (ATP-hydrolyzing); A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent [...]


ensembl_gene_id: Ssed_0010
symbol: Ssed_0010
gene_biotype: protein_coding
description:
  LamB/YcsF family protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.


ensembl_gene_id: Ssed_0020
symbol: tusA
gene_biotype: protein_coding
description:
  SirA family protein; Sulfur carrier protein which probably makes part of a sulfur- relay system; Belongs to the sulfur carrier protein TusA family.


ensembl_gene_id: Ssed_0021
symbol: Ssed_0021
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_0016 YbaK/EbsC protein; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.


ensembl_gene_id: Ssed_0022
symbol: fadA
gene_biotype: protein_coding
description:
  Acetyl-CoA C-acyltransferase; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.


ensembl_gene_id: Ssed_0023
symbol: fadB
gene_biotype: protein_coding
description:
  Fatty oxidation complex, alpha subunit FadB; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.


ensembl_gene_id: Ssed_0026
symbol: Ssed_0026
gene_biotype: protein_coding
description:
  Potassium uptake protein, TrkH family; Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA; Belongs to the TrkH potassium transport family.


ensembl_gene_id: Ssed_0034
symbol: fmt
gene_biotype: protein_coding
description:
  methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.


ensembl_gene_id: Ssed_0035
symbol: def
gene_biotype: protein_coding
description:
  Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.


ensembl_gene_id: Ssed_0041
symbol: tsaC
gene_biotype: protein_coding
description:
  SUA5/YciO/YrdC/YwlC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.


ensembl_gene_id: Ssed_0042
symbol: hemF
gene_biotype: protein_coding
description:
  Coproporphyrinogen oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX.


ensembl_gene_id: Ssed_0043
symbol: aroE
gene_biotype: protein_coding
description:
  Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).


ensembl_gene_id: Ssed_0051
symbol: Ssed_0051
gene_biotype: protein_coding
description:
  KEGG: shw:Sputw3181_0490 RNA polymerase, sigma 28 subunit, FliA/WhiG family; Belongs to the sigma-70 factor family.


ensembl_gene_id: Ssed_0052
symbol: Ssed_0052
gene_biotype: protein_coding
description:
  Flagellar basal body-associated protein FliL; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.


ensembl_gene_id: Ssed_0056
symbol: Ssed_0056
gene_biotype: protein_coding
description:
  Flagellar hook-associated 2 domain protein; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.


ensembl_gene_id: Ssed_0057
symbol: Ssed_0057
gene_biotype: protein_coding
description:
  Flagellin domain protein; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.


ensembl_gene_id: Ssed_0062
symbol: flgI
gene_biotype: protein_coding
description:
  Flagellar P-ring protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.


ensembl_gene_id: Ssed_0063
symbol: flgH
gene_biotype: protein_coding
description:
  Flagellar L-ring protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.


ensembl_gene_id: Ssed_0064
symbol: Ssed_0064
gene_biotype: protein_coding
description:
  KEGG: spc:Sputcn32_3463 flagellar basal-body rod protein FlgG; Belongs to the flagella basal body rod proteins family.


ensembl_gene_id: Ssed_0067
symbol: Ssed_0067
gene_biotype: protein_coding
description:
  Flagellar hook capping protein; Required for flagellar hook formation. May act as a scaffolding protein.


ensembl_gene_id: Ssed_0068
symbol: Ssed_0068
gene_biotype: protein_coding
description:
  KEGG: shw:Sputw3181_0472 flagellar basal-body rod protein FlgC; Belongs to the flagella basal body rod proteins family.


ensembl_gene_id: Ssed_0069
symbol: Ssed_0069
gene_biotype: protein_coding
description:
  Flagellar basal-body rod protein FlgB; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.


ensembl_gene_id: Ssed_0070
symbol: Ssed_0070
gene_biotype: protein_coding
description:
  SAF domain; Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P- ring assembly; Belongs to the FlgA family.


ensembl_gene_id: Ssed_0077
symbol: Ssed_0077
gene_biotype: protein_coding
description:
  Flagellar M-ring protein FliF; The M ring may be actively involved in energy transduction. Belongs to the FliF family.


ensembl_gene_id: Ssed_0082
symbol: Ssed_0082
gene_biotype: protein_coding
description:
  Flagellar motor switch protein FliN; FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliN/MopA/SpaO family.


ensembl_gene_id: Ssed_0083
symbol: fliP
gene_biotype: protein_coding
description:
  Triacylglycerol lipase; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family.


ensembl_gene_id: Ssed_0085
symbol: Ssed_0085
gene_biotype: protein_coding
description:
  Flagellar biosynthetic protein FliR; Role in flagellar biosynthesis. Belongs to the FliR/MopE/SpaR family.


ensembl_gene_id: Ssed_0086
symbol: flhB
gene_biotype: protein_coding
description:
  Flagellar biosynthetic protein FlhB; Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the type III secretion exporter family.


ensembl_gene_id: Ssed_0087
symbol: flhA
gene_biotype: protein_coding
description:
  Flagellar biosynthesis protein FlhA; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.


ensembl_gene_id: Ssed_0090
symbol: Ssed_0090
gene_biotype: protein_coding
description:
  KEGG: shw:Sputw3181_0039 oxygen-independent coproporphyrinogen III oxidase; Belongs to the anaerobic coproporphyrinogen-III oxidase family.


ensembl_gene_id: Ssed_0092
symbol: yihI
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis. Belongs to the YihI family.


ensembl_gene_id: Ssed_0095
symbol: engB
gene_biotype: protein_coding
description:
  GTP-binding protein, HSR1-related; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.


ensembl_gene_id: Ssed_0096
symbol: polA
gene_biotype: protein_coding
description:
  DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.


ensembl_gene_id: Ssed_0097
symbol: Ssed_0097
gene_biotype: protein_coding
description:
  ThiJ/PfpI domain protein; Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate; Belongs to the peptidase C56 family.


ensembl_gene_id: Ssed_0099
symbol: glpE
gene_biotype: protein_coding
description:
  Rhodanese domain protein; Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.


ensembl_gene_id: Ssed_0100
symbol: tdh
gene_biotype: protein_coding
description:
  L-threonine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family.


ensembl_gene_id: Ssed_0101
symbol: kbl
gene_biotype: protein_coding
description:
  Glycine C-acetyltransferase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.


ensembl_gene_id: Ssed_0104
symbol: Ssed_0104
gene_biotype: protein_coding
description:
  three-deoxy-D-manno-octulosonic-acid transferase domain protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.


ensembl_gene_id: Ssed_0105
symbol: kdkA
gene_biotype: protein_coding
description:
  Lipopolysaccharide kinase; Catalyzes the ATP-dependent phosphorylation of the 3-deoxy-D- manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position; Belongs to the protein kinase superfamily. KdkA/RfaP family.


ensembl_gene_id: Ssed_0106
symbol: Ssed_0106
gene_biotype: protein_coding
description:
  dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family.


ensembl_gene_id: Ssed_0107
symbol: Ssed_0107
gene_biotype: protein_coding
description:
  KEGG: abo:ABO_0910 dTDP-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.


ensembl_gene_id: Ssed_0108
symbol: Ssed_0108
gene_biotype: protein_coding
description:
  dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.


ensembl_gene_id: Ssed_0112
symbol: Ssed_0112
gene_biotype: protein_coding
description:
  Glycerol dehydrogenase-like protein; KEGG: chy:CHY_2583 putative glycerol-1-phosphate dehydrogenase.


ensembl_gene_id: Ssed_0115
symbol: coaD
gene_biotype: protein_coding
description:
  Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.


ensembl_gene_id: Ssed_0117
symbol: mutM
gene_biotype: protein_coding
description:
  DNA-formamidopyrimidine glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.


ensembl_gene_id: Ssed_0119
symbol: moaA
gene_biotype: protein_coding
description:
  Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.


ensembl_gene_id: Ssed_0120
symbol: Ssed_0120
gene_biotype: protein_coding
description:
  Molybdopterin-guanine dinucleotide biosynthesis protein B; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.


ensembl_gene_id: Ssed_0121
symbol: mobA
gene_biotype: protein_coding
description:
  Molybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family.


ensembl_gene_id: Ssed_0128
symbol: Ssed_0128
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.


ensembl_gene_id: Ssed_0149
symbol: Ssed_0149
gene_biotype: protein_coding
description:
  KEGG: saz:Sama_3549 transcriptional regulator, LyrR family; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_0152
symbol: Ssed_0152
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_0031 efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: Ssed_0161
symbol: Ssed_0161
gene_biotype: protein_coding
description:
  KEGG: ppr:PBPRB1939 hypothetical transcriptional regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_0163
symbol: rlmJ
gene_biotype: protein_coding
description:
  Protein of unknown function DUF519; Specifically methylates the adenine in position 2030 of 23S rRNA.


ensembl_gene_id: Ssed_0164
symbol: rsmJ
gene_biotype: protein_coding
description:
  Protein of unknown function DUF548; Specifically methylates the guanosine in position 1516 of 16S rRNA.


ensembl_gene_id: Ssed_0170
symbol: greB
gene_biotype: protein_coding
description:
  Transcription elongation factor GreB; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.


ensembl_gene_id: Ssed_0171
symbol: Ssed_0171
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_3635 thiamine pyrophosphate enzyme domain protein TPP-binding; Belongs to the TPP enzyme family.


ensembl_gene_id: Ssed_0176
symbol: bioH
gene_biotype: protein_coding
description:
  Carboxylesterase; The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.


ensembl_gene_id: Ssed_0179
symbol: nfuA
gene_biotype: protein_coding
description:
  HesB/YadR/YfhF-family protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.


ensembl_gene_id: Ssed_0182
symbol: cheB
gene_biotype: protein_coding
description:
  Protein-glutamate methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.


ensembl_gene_id: Ssed_0183
symbol: Ssed_0183
gene_biotype: protein_coding
description:
  Protein-glutamate O-methyltransferase; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.


ensembl_gene_id: Ssed_0190
symbol: cyoE
gene_biotype: protein_coding
description:
  Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.


ensembl_gene_id: Ssed_0197
symbol: Ssed_0197
gene_biotype: protein_coding
description:
  Cytochrome-c oxidase; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.


ensembl_gene_id: Ssed_0198
symbol: Ssed_0198
gene_biotype: protein_coding
description:
  Cytochrome-c oxidase; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).


ensembl_gene_id: Ssed_0199
symbol: Ssed_0199
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.


ensembl_gene_id: Ssed_0200
symbol: lexA
gene_biotype: protein_coding
description:
  Repressor lexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.


ensembl_gene_id: Ssed_0210
symbol: Ssed_0210
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_3534 heavy metal efflux pump, CzcA family; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: Ssed_0211
symbol: Ssed_0211
gene_biotype: protein_coding
description:
  Membrane-fusion protein-like protein; KEGG: slo:Shew_3535 efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: Ssed_0218
symbol: Ssed_0218
gene_biotype: protein_coding
description:
  Putative methyltransferase; Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle; Belongs to the methyltransferase superfamily. RsmD family.


ensembl_gene_id: Ssed_0219
symbol: ftsY
gene_biotype: protein_coding
description:
  Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.


ensembl_gene_id: Ssed_0220
symbol: ftsE
gene_biotype: protein_coding
description:
  Cell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division.


ensembl_gene_id: Ssed_0221
symbol: Ssed_0221
gene_biotype: protein_coding
description:
  Protein of unknown function DUF214; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.


ensembl_gene_id: Ssed_0222
symbol: rpoH
gene_biotype: protein_coding
description:
  RNA polymerase, sigma 32 subunit, RpoH; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.


ensembl_gene_id: Ssed_0225
symbol: menH
gene_biotype: protein_coding
description:
  Alpha/beta hydrolase fold; Catalyzes a proton abstraction reaction that results in 2,5- elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6- hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).


ensembl_gene_id: Ssed_0226
symbol: menD
gene_biotype: protein_coding
description:
  2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylic acid synthase/2-oxoglutarate decarboxylase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).


ensembl_gene_id: Ssed_0229
symbol: Ssed_0229
gene_biotype: protein_coding
description:
  KEGG: spc:Sputcn32_0627 anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: Ssed_0238
symbol: Ssed_0238
gene_biotype: protein_coding
description:
  KEGG: saz:Sama_2899 transcriptional regulator-like protein; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_0253
symbol: Ssed_0253
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_3589 transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_0265
symbol: trmL
gene_biotype: protein_coding
description:
  RNA methyltransferase, TrmH family, group 2; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.


ensembl_gene_id: Ssed_0266
symbol: Ssed_0266
gene_biotype: protein_coding
description:
  KEGG: ppr:PBPRA2008 putative transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_0269
symbol: Ssed_0269
gene_biotype: protein_coding
description:
  KEGG: shm:Shewmr7_3772 aldehyde dehydrogenase (NAD(+)); Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: Ssed_0272
symbol: Ssed_0272
gene_biotype: protein_coding
description:
  KEGG: vfi:VF0021 transcriptional regulators, LysR family; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_0273
symbol: Ssed_0273
gene_biotype: protein_coding
description:
  KEGG: shm:Shewmr7_2230 flavocytochrome c; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.


ensembl_gene_id: Ssed_0276
symbol: Ssed_0276
gene_biotype: protein_coding
description:
  KEGG: sfr:Sfri_3892 transcriptional regulator, LysR family protein; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_0281
symbol: Ssed_0281
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_3568 cation diffusion facilitator family transporter; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.


ensembl_gene_id: Ssed_0282
symbol: ntrC
gene_biotype: protein_coding
description:
  Nitrogen metabolism transcriptional regulator, NtrC, fis family; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.


ensembl_gene_id: Ssed_0289
symbol: Ssed_0289
gene_biotype: protein_coding
description:
  KEGG: shm:Shewmr7_3722 sodium:dicarboxylate symporter; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: Ssed_0305
symbol: dtd
gene_biotype: protein_coding
description:
  D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family.


ensembl_gene_id: Ssed_0307
symbol: azoR
gene_biotype: protein_coding
description:
  (acyl-carrier-protein) phosphodiesterase; Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity; Belongs to the azoreductase type 1 family.


ensembl_gene_id: Ssed_0310
symbol: Ssed_0310
gene_biotype: protein_coding
description:
  KEGG: shn:Shewana3_0326 beta-ketoacyl synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: Ssed_0313
symbol: Ssed_0313
gene_biotype: protein_coding
description:
  KEGG: shw:Sputw3181_0288 beta-ketoacyl synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: Ssed_0317
symbol: Ssed_0317
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).


ensembl_gene_id: Ssed_0324
symbol: acpP
gene_biotype: protein_coding
description:
  Phosphopantetheine-binding; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.


ensembl_gene_id: Ssed_0329
symbol: recG
gene_biotype: protein_coding
description:
  ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily.


ensembl_gene_id: Ssed_0332
symbol: trmH
gene_biotype: protein_coding
description:
  tRNA guanosine-2'-O-methyltransferase; Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.


ensembl_gene_id: Ssed_0334
symbol: Ssed_0334
gene_biotype: protein_coding
description:
  GTP diphosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.


ensembl_gene_id: Ssed_0335
symbol: rpoZ
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.


ensembl_gene_id: Ssed_0344
symbol: Ssed_0344
gene_biotype: protein_coding
description:
  KEGG: son:SO3058 flavocytochrome c flavin subunit, putative; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.


ensembl_gene_id: Ssed_0350
symbol: Ssed_0350
gene_biotype: protein_coding
description:
  KEGG: sfr:Sfri_3128 anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family protein; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: Ssed_0372
symbol: Ssed_0372
gene_biotype: protein_coding
description:
  Inorganic diphosphatase; KEGG: ppr:PBPRB1355 putative manganese-dependent inorganic pyrophosphatase.


ensembl_gene_id: Ssed_0373
symbol: adk
gene_biotype: protein_coding
description:
  Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.


ensembl_gene_id: Ssed_0378
symbol: rph
gene_biotype: protein_coding
description:
  tRNA nucleotidyltransferase; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.


ensembl_gene_id: Ssed_0379
symbol: pyrE
gene_biotype: protein_coding
description:
  Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).


ensembl_gene_id: Ssed_0382
symbol: slmA
gene_biotype: protein_coding
description:
  Transcriptional regulator, TetR family; Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.


ensembl_gene_id: Ssed_0383
symbol: dut
gene_biotype: protein_coding
description:
  dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.


ensembl_gene_id: Ssed_0384
symbol: Ssed_0384
gene_biotype: protein_coding
description:
  Phosphopantothenoylcysteine decarboxylase, Phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.


ensembl_gene_id: Ssed_0388
symbol: argA
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_3478 amino-acid N-acetyltransferase; Belongs to the acetyltransferase family. ArgA subfamily.


ensembl_gene_id: Ssed_0393
symbol: leuA
gene_biotype: protein_coding
description:
  2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.


ensembl_gene_id: Ssed_0394
symbol: leuB
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.


ensembl_gene_id: Ssed_0395
symbol: leuC
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.


ensembl_gene_id: Ssed_0396
symbol: leuD
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.


ensembl_gene_id: Ssed_0399
symbol: glpK
gene_biotype: protein_coding
description:
  Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.


ensembl_gene_id: Ssed_0402
symbol: rsmH
gene_biotype: protein_coding
description:
  S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.


ensembl_gene_id: Ssed_0403
symbol: ftsL
gene_biotype: protein_coding
description:
  Cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.


ensembl_gene_id: Ssed_0404
symbol: ftsI
gene_biotype: protein_coding
description:
  Peptidoglycan glycosyltransferase; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily.


ensembl_gene_id: Ssed_0405
symbol: murE
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.


ensembl_gene_id: Ssed_0406
symbol: murF
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl- D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.


ensembl_gene_id: Ssed_0407
symbol: mraY
gene_biotype: protein_coding
description:
  Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.


ensembl_gene_id: Ssed_0408
symbol: murD
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.


ensembl_gene_id: Ssed_0409
symbol: ftsW
gene_biotype: protein_coding
description:
  Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily.


ensembl_gene_id: Ssed_0410
symbol: murG
gene_biotype: protein_coding
description:
  Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.


ensembl_gene_id: Ssed_0412
symbol: ftsQ
gene_biotype: protein_coding
description:
  Polypeptide-transport-associated domain protein, FtsQ-type; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.


ensembl_gene_id: Ssed_0413
symbol: ftsA
gene_biotype: protein_coding
description:
  Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.


ensembl_gene_id: Ssed_0414
symbol: ftsZ
gene_biotype: protein_coding
description:
  Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.


ensembl_gene_id: Ssed_0415
symbol: lpxC
gene_biotype: protein_coding
description:
  UDP-3-0-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family.


ensembl_gene_id: Ssed_0418
symbol: secA
gene_biotype: protein_coding
description:
  Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family.


ensembl_gene_id: Ssed_0420
symbol: yacG
gene_biotype: protein_coding
description:
  Protein of unknown function DUF329; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C- terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.


ensembl_gene_id: Ssed_0421
symbol: zapD
gene_biotype: protein_coding
description:
  Protein of unknown function DUF1342; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.


ensembl_gene_id: Ssed_0422
symbol: coaE
gene_biotype: protein_coding
description:
  Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.


ensembl_gene_id: Ssed_0423
symbol: Ssed_0423
gene_biotype: protein_coding
description:
  Prepilin peptidase; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.


ensembl_gene_id: Ssed_0427
symbol: Ssed_0427
gene_biotype: protein_coding
description:
  Nicotinate-nucleotide diphosphorylase (carboxylating); KEGG: shw:Sputw3181_0522 nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family.


ensembl_gene_id: Ssed_0431
symbol: Ssed_0431
gene_biotype: protein_coding
description:
  Pyruvate dehydrogenase (acetyl-transferring); Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


ensembl_gene_id: Ssed_0432
symbol: Ssed_0432
gene_biotype: protein_coding
description:
  Dihydrolipoyllysine-residue succinyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


ensembl_gene_id: Ssed_0440
symbol: hemE
gene_biotype: protein_coding
description:
  Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.


ensembl_gene_id: Ssed_0444
symbol: purH
gene_biotype: protein_coding
description:
  IMP cyclohydrolase; KEGG: slo:Shew_3412 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase.


ensembl_gene_id: Ssed_0451
symbol: Ssed_0451
gene_biotype: protein_coding
description:
  KEGG: sbl:Sbal_0481 transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_0453
symbol: Ssed_0453
gene_biotype: protein_coding
description:
  KEGG: sbl:Sbal_0483 drug resistance transporter, EmrB/QacA subfamily; Belongs to the major facilitator superfamily.


ensembl_gene_id: Ssed_0461
symbol: Ssed_0461
gene_biotype: protein_coding
description:
  Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family.


ensembl_gene_id: Ssed_0468
symbol: ubiA
gene_biotype: protein_coding
description:
  4-hydroxybenzoate polyprenyl transferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.


ensembl_gene_id: Ssed_0482
symbol: Ssed_0482
gene_biotype: protein_coding
description:
  Cytochrome c, putative; Respiratory sulfite reductase that catalyzes the reduction of sulfite to sulfide in a single step, consuming six electrons in the process; Belongs to the multiheme cytochrome c family.


ensembl_gene_id: Ssed_0485
symbol: Ssed_0485
gene_biotype: protein_coding
description:
  Cytochrome c biogenesis factor-like protein; KEGG: shn:Shewana3_0492 formate-dependent nitrite reductase, NrfG protein.


ensembl_gene_id: Ssed_0505
symbol: ubiD
gene_biotype: protein_coding
description:
  UbiD family decarboxylase; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.


ensembl_gene_id: Ssed_0520
symbol: Ssed_0520
gene_biotype: protein_coding
description:
  KEGG: shn:Shewana3_3964 transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_0529
symbol: Ssed_0529
gene_biotype: protein_coding
description:
  Methyl-accepting chemotaxis protein-like protein; KEGG: ppr:PBPRB1868 hypothetical chemotaxis transducer.


ensembl_gene_id: Ssed_0530
symbol: hslU
gene_biotype: protein_coding
description:
  Heat shock protein HslVU, ATPase subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.


ensembl_gene_id: Ssed_0531
symbol: hslV
gene_biotype: protein_coding
description:
  20S proteasome, A and B subunits; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.


ensembl_gene_id: Ssed_0534
symbol: priA
gene_biotype: protein_coding
description:
  Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.


ensembl_gene_id: Ssed_0560
symbol: Ssed_0560
gene_biotype: protein_coding
description:
  Rod shape-determining protein MreD; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins. Belongs to the MreD family.


ensembl_gene_id: Ssed_0561
symbol: Ssed_0561
gene_biotype: protein_coding
description:
  Maf protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.


ensembl_gene_id: Ssed_0576
symbol: Ssed_0576
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_0419 glyceraldehyde-3-phosphate dehydrogenase, type I; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.


ensembl_gene_id: Ssed_0579
symbol: Ssed_0579
gene_biotype: protein_coding
description:
  KEGG: vpa:VP2406 putative LysR-like regular protein; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_0600
symbol: Ssed_0600
gene_biotype: protein_coding
description:
  Histone family protein DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.


ensembl_gene_id: Ssed_0610
symbol: cheD
gene_biotype: protein_coding
description:
  CheD; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.


ensembl_gene_id: Ssed_0612
symbol: fhs
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_0443 formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family.


ensembl_gene_id: Ssed_0619
symbol: Ssed_0619
gene_biotype: protein_coding
description:
  1-acylglycerol-3-phosphate O-acyltransferase; KEGG: slo:Shew_0450 1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.


ensembl_gene_id: Ssed_0620
symbol: rraB
gene_biotype: protein_coding
description:
  Protein of unknown function DUF1260; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.


ensembl_gene_id: Ssed_0623
symbol: Ssed_0623
gene_biotype: protein_coding
description:
  KEGG: shw:Sputw3181_0637 enoyl-CoA hydratase/isomerase; Belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: Ssed_0625
symbol: rapA
gene_biotype: protein_coding
description:
  SNF2-related protein; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily.


ensembl_gene_id: Ssed_0629
symbol: Ssed_0629
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_0466 acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: Ssed_0630
symbol: Ssed_0630
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_0467 efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: Ssed_0631
symbol: Ssed_0631
gene_biotype: protein_coding
description:
  Carbonate dehydratase; KEGG: slo:Shew_0468 transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_0641
symbol: groS
gene_biotype: protein_coding
description:
  Chaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.


ensembl_gene_id: Ssed_0642
symbol: groL
gene_biotype: protein_coding
description:
  Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.


ensembl_gene_id: Ssed_0658
symbol: Ssed_0658
gene_biotype: protein_coding
description:
  KEGG: aha:AHA_0900 transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_0670
symbol: Ssed_0670
gene_biotype: protein_coding
description:
  KEGG: ppr:PBPRB1044 putative transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_0677
symbol: Ssed_0677
gene_biotype: protein_coding
description:
  KEGG: vpa:VPA0175 transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_0680
symbol: Ssed_0680
gene_biotype: protein_coding
description:
  Peptidyl-prolyl cis-trans isomerase, cyclophilin type; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.


ensembl_gene_id: Ssed_0681
symbol: Ssed_0681
gene_biotype: protein_coding
description:
  Phospholipase A(1); Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities. Belongs to the phospholipase A1 family.


ensembl_gene_id: Ssed_0686
symbol: Ssed_0686
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_0296 heat shock protein HSP20; Belongs to the small heat shock protein (HSP20) family.


ensembl_gene_id: Ssed_0688
symbol: Ssed_0688
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_0505 nitrite reductase (cytochrome; ammonia-forming); Belongs to the cytochrome c-552 family.


ensembl_gene_id: Ssed_0695
symbol: Ssed_0695
gene_biotype: protein_coding
description:
  ApbE-like lipoprotein; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. Belongs to the ApbE family.


ensembl_gene_id: Ssed_0703
symbol: fumC
gene_biotype: protein_coding
description:
  Fumarase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.


ensembl_gene_id: Ssed_0718
symbol: Ssed_0718
gene_biotype: protein_coding
description:
  KEGG: ana:all3436 hypothetical protein; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.


ensembl_gene_id: Ssed_0726
symbol: Ssed_0726
gene_biotype: protein_coding
description:
  RNA polymerase, sigma 54 subunit, RpoN; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.


ensembl_gene_id: Ssed_0728
symbol: lptA
gene_biotype: protein_coding
description:
  OstA family protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.


ensembl_gene_id: Ssed_0729
symbol: lptC
gene_biotype: protein_coding
description:
  Protein of unknown function DUF1239; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family.


ensembl_gene_id: Ssed_0730
symbol: Ssed_0730
gene_biotype: protein_coding
description:
  3-deoxy-manno-octulosonate-8-phosphatase; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family.


ensembl_gene_id: Ssed_0739
symbol: murA
gene_biotype: protein_coding
description:
  UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.


ensembl_gene_id: Ssed_0747
symbol: rplM
gene_biotype: protein_coding
description:
  Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.


ensembl_gene_id: Ssed_0748
symbol: rpsI
gene_biotype: protein_coding
description:
  Ribosomal protein S9; KEGG: shw:Sputw3181_3430 ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.


ensembl_gene_id: Ssed_0750
symbol: purA
gene_biotype: protein_coding
description:
  Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.


ensembl_gene_id: Ssed_0752
symbol: rnr
gene_biotype: protein_coding
description:
  Exoribonuclease II; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.


ensembl_gene_id: Ssed_0753
symbol: rlmB
gene_biotype: protein_coding
description:
  RNA methyltransferase, TrmH family, group 3; Specifically methylates the ribose of guanosine 2251 in 23S rRNA.


ensembl_gene_id: Ssed_0758
symbol: priB
gene_biotype: protein_coding
description:
  Single-strand binding protein/primosomal replication protein N; Binds single-stranded DNA at the primosome assembly site (PAS); Belongs to the PriB family.


ensembl_gene_id: Ssed_0759
symbol: rpsR
gene_biotype: protein_coding
description:
  Ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.


ensembl_gene_id: Ssed_0762
symbol: Ssed_0762
gene_biotype: protein_coding
description:
  Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily.


ensembl_gene_id: Ssed_0763
symbol: alr
gene_biotype: protein_coding
description:
  Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.


ensembl_gene_id: Ssed_0766
symbol: dusA
gene_biotype: protein_coding
description:
  TIM-barrel protein, YjbN family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily.


ensembl_gene_id: Ssed_0777
symbol: cpdA
gene_biotype: protein_coding
description:
  Calcineurin phosphoesterase C-terminal domain protein; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.


ensembl_gene_id: Ssed_0779
symbol: parE
gene_biotype: protein_coding
description:
  DNA topoisomerase (ATP-hydrolyzing); Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily.


ensembl_gene_id: Ssed_0781
symbol: parC
gene_biotype: protein_coding
description:
  DNA topoisomerase (ATP-hydrolyzing); Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.


ensembl_gene_id: Ssed_0788
symbol: psd
gene_biotype: protein_coding
description:
  Phosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).


ensembl_gene_id: Ssed_0789
symbol: rsgA
gene_biotype: protein_coding
description:
  Ribosome small subunit-dependent GTPase A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.


ensembl_gene_id: Ssed_0790
symbol: orn
gene_biotype: protein_coding
description:
  Exonuclease, RNase T and DNA polymerase III; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family.


ensembl_gene_id: Ssed_0792
symbol: nnrE
gene_biotype: protein_coding
description:
  Carbohydrate kinase, YjeF-related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.  Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...]


ensembl_gene_id: Ssed_0795
symbol: mutL
gene_biotype: protein_coding
description:
  DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.


ensembl_gene_id: Ssed_0796
symbol: miaA1
gene_biotype: protein_coding
description:
  tRNA isopentenyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.


ensembl_gene_id: Ssed_0797
symbol: hfq
gene_biotype: protein_coding
description:
  RNA chaperone Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.


ensembl_gene_id: Ssed_0798
symbol: hflX
gene_biotype: protein_coding
description:
  GTP-binding protein, HSR1-related; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.


ensembl_gene_id: Ssed_0801
symbol: Ssed_0801
gene_biotype: protein_coding
description:
  Ubiquinol--cytochrome-c reductase; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.


ensembl_gene_id: Ssed_0802
symbol: Ssed_0802
gene_biotype: protein_coding
description:
  Cytochrome b/b6, N-terminal domain; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.


ensembl_gene_id: Ssed_0806
symbol: Ssed_0806
gene_biotype: protein_coding
description:
  KEGG: sdn:Sden_3196 glutamine amidotransferase of anthranilate synthase or para-aminobenzoate synthase.


ensembl_gene_id: Ssed_0809
symbol: argD
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_0578 acetylornithine and succinylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.


ensembl_gene_id: Ssed_0811
symbol: astD
gene_biotype: protein_coding
description:
  Aldehyde dehydrogenase; Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.


ensembl_gene_id: Ssed_0819
symbol: Ssed_0819
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_0781 peptidase S8 and S53, subtilisin, kexin, sedolisin; Belongs to the peptidase S8 family.


ensembl_gene_id: Ssed_0821
symbol: Ssed_0821
gene_biotype: protein_coding
description:
  Pseudouridylate synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.


ensembl_gene_id: Ssed_0829
symbol: Ssed_0829
gene_biotype: protein_coding
description:
  Alkyl hydroperoxide reductase/thiol specific antioxidant/Mal allergen; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.


ensembl_gene_id: Ssed_0838
symbol: Ssed_0838
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_0809 formate dehydrogenase, alpha subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: Ssed_0840
symbol: prfB
gene_biotype: protein_coding
description:
  Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.


ensembl_gene_id: Ssed_0841
symbol: lysS
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_0812 lysyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family.


ensembl_gene_id: Ssed_0843
symbol: Ssed_0843
gene_biotype: protein_coding
description:
  KEGG: cps:CPS_1154 RNA pseudouridine synthase family protein; Belongs to the pseudouridine synthase RsuA family.


ensembl_gene_id: Ssed_0844
symbol: nagB
gene_biotype: protein_coding
description:
  Glucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion; Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.


ensembl_gene_id: Ssed_0854
symbol: Ssed_0854
gene_biotype: protein_coding
description:
  Aminotransferase, class V; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.


ensembl_gene_id: Ssed_0857
symbol: Ssed_0857
gene_biotype: protein_coding
description:
  Protein of unknown function DUF84; Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.


ensembl_gene_id: Ssed_0859
symbol: Ssed_0859
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_0740 L-serine dehydratase 1; Belongs to the iron-sulfur dependent L-serine dehydratase family.


ensembl_gene_id: Ssed_0862
symbol: Ssed_0862
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_0743 sodium:dicarboxylate symporter; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: Ssed_0871
symbol: Ssed_0871
gene_biotype: protein_coding
description:
  KEGG: rfr:Rfer_3509 thiamine pyrophosphate enzyme-like TPP binding protein; Belongs to the TPP enzyme family.


ensembl_gene_id: Ssed_0873
symbol: metK
gene_biotype: protein_coding
description:
  Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.


ensembl_gene_id: Ssed_0874
symbol: Ssed_0874
gene_biotype: protein_coding
description:
  Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.


ensembl_gene_id: Ssed_0875
symbol: Ssed_0875
gene_biotype: protein_coding
description:
  Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating); Catalyzes the NAD-dependent conversion of D-erythrose 4- phosphate to 4-phosphoerythronate.


ensembl_gene_id: Ssed_0877
symbol: Ssed_0877
gene_biotype: protein_coding
description:
  Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.


ensembl_gene_id: Ssed_0888
symbol: Ssed_0888
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_0765 acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: Ssed_0889
symbol: Ssed_0889
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_0766 efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: Ssed_0890
symbol: srmB
gene_biotype: protein_coding
description:
  DEAD/DEAH box helicase domain protein; DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity; Belongs to the DEAD box helicase family. SrmB subfamily.


ensembl_gene_id: Ssed_0891
symbol: Ssed_0891
gene_biotype: protein_coding
description:
  Methyltransferase small; Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).


ensembl_gene_id: Ssed_0892
symbol: Ssed_0892
gene_biotype: protein_coding
description:
  Branched-chain amino acid transport system II carrier protein; Component of the transport system for branched-chain amino acids.


ensembl_gene_id: Ssed_0893
symbol: xerD
gene_biotype: protein_coding
description:
  Tyrosine recombinase XerD; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.


ensembl_gene_id: Ssed_0894
symbol: Ssed_0894
gene_biotype: protein_coding
description:
  Thiol:disulfide interchange protein DsbC; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily.


ensembl_gene_id: Ssed_0896
symbol: Ssed_0896
gene_biotype: protein_coding
description:
  KEGG: shw:Sputw3181_0790 transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_0898
symbol: rpiA
gene_biotype: protein_coding
description:
  Ribose-5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.


ensembl_gene_id: Ssed_0901
symbol: Ssed_0901
gene_biotype: protein_coding
description:
  KEGG: shn:Shewana3_0884 transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_0907
symbol: Ssed_0907
gene_biotype: protein_coding
description:
  L-lactate permease; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family.


ensembl_gene_id: Ssed_0920
symbol: arnF
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane; Belongs to the ArnF family.


ensembl_gene_id: Ssed_0921
symbol: arnE
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane; Belongs to the ArnE family.


ensembl_gene_id: Ssed_0922
symbol: arnT
gene_biotype: protein_coding
description:
  undecaprenylphosphate-alpha-4-amino-4-deoxy-L- arabinosearabinosyltra nsferase; Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides. Belongs to the glycosyltransferase 83 family.


ensembl_gene_id: Ssed_0923
symbol: arnD
gene_biotype: protein_coding
description:
  Polysaccharide deacetylase; Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; Belongs to the polysaccharide deacetylase family. ArnD deformylase subfamily.


ensembl_gene_id: Ssed_0924
symbol: arnA
gene_biotype: protein_coding
description:
  Bifunctional polymyxin resistance ArnA protein (polymyxin resistanceprotein PmrI); Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; In the C-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic aci [...]


ensembl_gene_id: Ssed_0925
symbol: arnC
gene_biotype: protein_coding
description:
  Glycosyl transferase, group 2 family protein; Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.


ensembl_gene_id: Ssed_0926
symbol: arnB
gene_biotype: protein_coding
description:
  UDP-4-amino-4-deoxy-L-arabinose-- oxoglutarateaminotransferase; Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; Belongs to the DegT/DnrJ/EryC1 family. ArnB subfamily.


ensembl_gene_id: Ssed_0931
symbol: nrfA
gene_biotype: protein_coding
description:
  Nitrite reductase (cytochrome; Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process; Belongs to the cytochrome c-552 family.


ensembl_gene_id: Ssed_0937
symbol: Ssed_0937
gene_biotype: protein_coding
description:
  3-deoxy-7-phosphoheptulonate synthase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP).


ensembl_gene_id: Ssed_0954
symbol: rplU
gene_biotype: protein_coding
description:
  Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.


ensembl_gene_id: Ssed_0956
symbol: obg
gene_biotype: protein_coding
description:
  GTP1/OBG sub domain protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.


ensembl_gene_id: Ssed_0959
symbol: Ssed_0959
gene_biotype: protein_coding
description:
  Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.


ensembl_gene_id: Ssed_0962
symbol: apaH
gene_biotype: protein_coding
description:
  Bis(5'-nucleosyl)-tetraphosphatase (symmetrical); Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family.


ensembl_gene_id: Ssed_0964
symbol: rsmA
gene_biotype: protein_coding
description:
  Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.


ensembl_gene_id: Ssed_0965
symbol: pdxA
gene_biotype: protein_coding
description:
  4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).


ensembl_gene_id: Ssed_0966
symbol: surA
gene_biotype: protein_coding
description:
  PpiC-type peptidyl-prolyl cis-trans isomerase; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.


ensembl_gene_id: Ssed_0967
symbol: lptD
gene_biotype: protein_coding
description:
  Organic solvent tolerance protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.


ensembl_gene_id: Ssed_0970
symbol: djlA
gene_biotype: protein_coding
description:
  Heat shock protein DnaJ domain protein; Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.


ensembl_gene_id: Ssed_0973
symbol: purT
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazole carboxylase; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family.


ensembl_gene_id: Ssed_0997
symbol: Ssed_0997
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_0917 transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_1008
symbol: valS
gene_biotype: protein_coding
description:
  valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.


ensembl_gene_id: Ssed_1011
symbol: rsgA-2
gene_biotype: protein_coding
description:
  Putative GTPase; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.


ensembl_gene_id: Ssed_1014
symbol: pepA
gene_biotype: protein_coding
description:
  Leucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.


ensembl_gene_id: Ssed_1020
symbol: Ssed_1020
gene_biotype: protein_coding
description:
  Carboxypeptidase Taq; Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.


ensembl_gene_id: Ssed_1032
symbol: Ssed_1032
gene_biotype: protein_coding
description:
  KEGG: hch:HCH_06917 response regulator consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: Ssed_1044
symbol: Ssed_1044
gene_biotype: protein_coding
description:
  Beta-alanine--pyruvate transaminase; KEGG: slo:Shew_0966 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: Ssed_1046
symbol: Ssed_1046
gene_biotype: protein_coding
description:
  KEGG: she:Shewmr4_0147 sodium:dicarboxylate symporter; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: Ssed_1048
symbol: rbsK
gene_biotype: protein_coding
description:
  Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.


ensembl_gene_id: Ssed_1061
symbol: Ssed_1061
gene_biotype: protein_coding
description:
  Extracellular solute-binding protein, family 1; Required for the activity of the bacterial periplasmic transport system of putrescine; Belongs to the bacterial solute-binding protein PotD/PotF family.


ensembl_gene_id: Ssed_1062
symbol: potA
gene_biotype: protein_coding
description:
  Spermidine/putrescine ABC transporter ATPase subunit; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.


ensembl_gene_id: Ssed_1064
symbol: Ssed_1064
gene_biotype: protein_coding
description:
  Ornithine carbamoyltransferase; KEGG: slo:Shew_0976 binding-protein-dependent transport systems inner membrane component.


ensembl_gene_id: Ssed_1067
symbol: Ssed_1067
gene_biotype: protein_coding
description:
  KEGG: bra:BRADO5800 putative glutamate synthase (NADPH); putative 2-ketoglutarate: NADP oxidoreductase, gamma subunit (KorC-like).


ensembl_gene_id: Ssed_1072
symbol: rpoD
gene_biotype: protein_coding
description:
  RNA polymerase, sigma 70 subunit, RpoD family; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.


ensembl_gene_id: Ssed_1073
symbol: dnaG
gene_biotype: protein_coding
description:
  DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.


ensembl_gene_id: Ssed_1075
symbol: rpsU
gene_biotype: protein_coding
description:
  KEGG: shw:Sputw3181_3057 ribosomal protein S21; Belongs to the bacterial ribosomal protein bS21 family.


ensembl_gene_id: Ssed_1076
symbol: tsaD
gene_biotype: protein_coding
description:
  O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.


ensembl_gene_id: Ssed_1077
symbol: plsY
gene_biotype: protein_coding
description:
  Protein of unknown function DUF205; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.


ensembl_gene_id: Ssed_1078
symbol: Ssed_1078
gene_biotype: protein_coding
description:
  Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.


ensembl_gene_id: Ssed_1080
symbol: uppP
gene_biotype: protein_coding
description:
  Undecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.


ensembl_gene_id: Ssed_1084
symbol: cca
gene_biotype: protein_coding
description:
  Metal dependent phosphohydrolase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.


ensembl_gene_id: Ssed_1089
symbol: Ssed_1089
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_1013 aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily.


ensembl_gene_id: Ssed_1095
symbol: erpA
gene_biotype: protein_coding
description:
  Iron-sulfur cluster assembly accessory protein; Required for insertion of 4Fe-4S clusters for at least IspG.


ensembl_gene_id: Ssed_1102
symbol: anmK
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family.


ensembl_gene_id: Ssed_1104
symbol: tyrS
gene_biotype: protein_coding
description:
  Tyrosine--tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.


ensembl_gene_id: Ssed_1110
symbol: Ssed_1110
gene_biotype: protein_coding
description:
  Outer membrane receptor protein mostly Fe transport-like protein; KEGG: mmr:Mmar10_1982 TonB-dependent receptor, plug.


ensembl_gene_id: Ssed_1115
symbol: mtnN
gene_biotype: protein_coding
description:
  Adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.


ensembl_gene_id: Ssed_1119
symbol: Ssed_1119
gene_biotype: protein_coding
description:
  Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.


ensembl_gene_id: Ssed_1120
symbol: Ssed_1120
gene_biotype: protein_coding
description:
  Betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid.


ensembl_gene_id: Ssed_1121
symbol: betI
gene_biotype: protein_coding
description:
  Transcriptional regulator, TetR family protein; Repressor involved in choline regulation of the bet genes.


ensembl_gene_id: Ssed_1129
symbol: Ssed_1129
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_1035 transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_1131
symbol: mutH
gene_biotype: protein_coding
description:
  DNA mismatch repair endonuclease MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair. Belongs to the MutH family.


ensembl_gene_id: Ssed_1132
symbol: rppH
gene_biotype: protein_coding
description:
  NUDIX hydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily.


ensembl_gene_id: Ssed_1135
symbol: thyA
gene_biotype: protein_coding
description:
  Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.


ensembl_gene_id: Ssed_1136
symbol: nhaA
gene_biotype: protein_coding
description:
  Na+/H+ antiporter NhaA; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.


ensembl_gene_id: Ssed_1138
symbol: Ssed_1138
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_1044 transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_1142
symbol: Ssed_1142
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_1048 RNA polymerase, sigma-24 subunit, ECF subfamily; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: Ssed_1143
symbol: Ssed_1143
gene_biotype: protein_coding
description:
  Anti sigma-E protein, RseA; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish  [...]


ensembl_gene_id: Ssed_1146
symbol: lepA
gene_biotype: protein_coding
description:
  GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.


ensembl_gene_id: Ssed_1148
symbol: rnc
gene_biotype: protein_coding
description:
  Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.


ensembl_gene_id: Ssed_1149
symbol: era
gene_biotype: protein_coding
description:
  GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.


ensembl_gene_id: Ssed_1151
symbol: pdxJ
gene_biotype: protein_coding
description:
  Pyridoxal phosphate biosynthetic protein PdxJ; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.


ensembl_gene_id: Ssed_1152
symbol: acpS
gene_biotype: protein_coding
description:
  Holo-(acyl-carrier-protein) synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.


ensembl_gene_id: Ssed_1158
symbol: ffh
gene_biotype: protein_coding
description:
  Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual componen [...]


ensembl_gene_id: Ssed_1160
symbol: rimM
gene_biotype: protein_coding
description:
  16S rRNA processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family.


ensembl_gene_id: Ssed_1161
symbol: trmD
gene_biotype: protein_coding
description:
  tRNA (guanine-N(1)-)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.


ensembl_gene_id: Ssed_1162
symbol: rplS
gene_biotype: protein_coding
description:
  Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.


ensembl_gene_id: Ssed_1175
symbol: Ssed_1175
gene_biotype: protein_coding
description:
  Aspartate kinase., Homoserine dehydrogenase; KEGG: slo:Shew_1079 aspartate kinase; In the C-terminal section; belongs to the homoserine dehydrogenase family.


ensembl_gene_id: Ssed_1176
symbol: thrB
gene_biotype: protein_coding
description:
  Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.


ensembl_gene_id: Ssed_1179
symbol: nfo
gene_biotype: protein_coding
description:
  Deoxyribonuclease IV (phage-T(4)-induced); Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.


ensembl_gene_id: Ssed_1185
symbol: tal
gene_biotype: protein_coding
description:
  Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.


ensembl_gene_id: Ssed_1192
symbol: murJ
gene_biotype: protein_coding
description:
  Integral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.


ensembl_gene_id: Ssed_1194
symbol: ileS
gene_biotype: protein_coding
description:
  isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.


ensembl_gene_id: Ssed_1195
symbol: lspA
gene_biotype: protein_coding
description:
  Signal peptidase II; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.


ensembl_gene_id: Ssed_1197
symbol: ispH
gene_biotype: protein_coding
description:
  4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.


ensembl_gene_id: Ssed_1213
symbol: Ssed_1213
gene_biotype: protein_coding
description:
  KEGG: shw:Sputw3181_3087 N-acetylglucosamine-6-phosphate deacetylase; Belongs to the metallo-dependent hydrolases superfamily. NagA family.


ensembl_gene_id: Ssed_1218
symbol: Ssed_1218
gene_biotype: protein_coding
description:
  Fe(II) trafficking protein YggX; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.


ensembl_gene_id: Ssed_1220
symbol: trmB
gene_biotype: protein_coding
description:
  tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.


ensembl_gene_id: Ssed_1224
symbol: Ssed_1224
gene_biotype: protein_coding
description:
  Carbonate dehydratase; KEGG: slo:Shew_1128 transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_1226
symbol: Ssed_1226
gene_biotype: protein_coding
description:
  Coproporphyrinogen dehydrogenase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.


ensembl_gene_id: Ssed_1227
symbol: Ssed_1227
gene_biotype: protein_coding
description:
  Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.


ensembl_gene_id: Ssed_1231
symbol: proC
gene_biotype: protein_coding
description:
  Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.


ensembl_gene_id: Ssed_1232
symbol: Ssed_1232
gene_biotype: protein_coding
description:
  Alanine racemase domain protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.


ensembl_gene_id: Ssed_1235
symbol: hemH
gene_biotype: protein_coding
description:
  Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.


ensembl_gene_id: Ssed_1236
symbol: Ssed_1236
gene_biotype: protein_coding
description:
  Putative Holliday junction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family.


ensembl_gene_id: Ssed_1242
symbol: Ssed_1242
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_1149 transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_1255
symbol: Ssed_1255
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_1163 efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: Ssed_1266
symbol: Ssed_1266
gene_biotype: protein_coding
description:
  KEGG: shw:Sputw3181_1226 efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: Ssed_1267
symbol: Ssed_1267
gene_biotype: protein_coding
description:
  KEGG: spc:Sputcn32_2787 acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: Ssed_1271
symbol: glyA
gene_biotype: protein_coding
description:
  Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.


ensembl_gene_id: Ssed_1272
symbol: nrdR
gene_biotype: protein_coding
description:
  Ribonucleotide reductase regulator NrdR-like protein; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.


ensembl_gene_id: Ssed_1273
symbol: Ssed_1273
gene_biotype: protein_coding
description:
  Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.


ensembl_gene_id: Ssed_1275
symbol: ribB
gene_biotype: protein_coding
description:
  3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.


ensembl_gene_id: Ssed_1276
symbol: ribH
gene_biotype: protein_coding
description:
  Riboflavin synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family.


ensembl_gene_id: Ssed_1277
symbol: nusB
gene_biotype: protein_coding
description:
  NusB antitermination factor; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.


ensembl_gene_id: Ssed_1278
symbol: thiL
gene_biotype: protein_coding
description:
  Thiamine-phosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.


ensembl_gene_id: Ssed_1279
symbol: Ssed_1279
gene_biotype: protein_coding
description:
  Phosphatidylglycerophosphatase; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).


ensembl_gene_id: Ssed_1280
symbol: Ssed_1280
gene_biotype: protein_coding
description:
  Methylase involved in ubiquinone/menaquinone biosynthesis-like protein; KEGG: gvi:glr1180 hypothetical protein.


ensembl_gene_id: Ssed_1286
symbol: rlmD
gene_biotype: protein_coding
description:
  RNA methyltransferase, TrmA family; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.


ensembl_gene_id: Ssed_1289
symbol: pyrG
gene_biotype: protein_coding
description:
  CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.


ensembl_gene_id: Ssed_1290
symbol: eno
gene_biotype: protein_coding
description:
  Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.


ensembl_gene_id: Ssed_1291
symbol: ftsB
gene_biotype: protein_coding
description:
  Septum formation initiator; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.


ensembl_gene_id: Ssed_1292
symbol: ispD
gene_biotype: protein_coding
description:
  4-diphosphocytidyl-2C-methyl-D-erythritol synthase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).


ensembl_gene_id: Ssed_1293
symbol: ispF
gene_biotype: protein_coding
description:
  2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).


ensembl_gene_id: Ssed_1294
symbol: truD
gene_biotype: protein_coding
description:
  Pseudouridylate synthase; Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family.


ensembl_gene_id: Ssed_1295
symbol: surE
gene_biotype: protein_coding
description:
  3'-nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.


ensembl_gene_id: Ssed_1296
symbol: pcm1
gene_biotype: protein_coding
description:
  Protein-L-isoaspartate(D-aspartate) O-methyltransferase; Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.


ensembl_gene_id: Ssed_1298
symbol: rpoS
gene_biotype: protein_coding
description:
  RNA polymerase, sigma 70 subunit, RpoD family; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.


ensembl_gene_id: Ssed_1299
symbol: mutS
gene_biotype: protein_coding
description:
  DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.


ensembl_gene_id: Ssed_1300
symbol: recA
gene_biotype: protein_coding
description:
  Calcium-transporting ATPase; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.


ensembl_gene_id: Ssed_1311
symbol: Ssed_1311
gene_biotype: protein_coding
description:
  Transcriptional regulator-like protein; KEGG: ppr:PBPRA0141 putative transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_1312
symbol: Ssed_1312
gene_biotype: protein_coding
description:
  KEGG: shn:Shewana3_3686 transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_1313
symbol: Ssed_1313
gene_biotype: protein_coding
description:
  Phosphatase; KEGG: aor:AO090010000317 predicted phosphatase homologous to the C-terminal domain of histone macroH2A1 Pfam: A1pp PROSITE: SIRTUIN.


ensembl_gene_id: Ssed_1317
symbol: Ssed_1317
gene_biotype: protein_coding
description:
  KEGG: aha:AHA_1950 transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_1318
symbol: alaS
gene_biotype: protein_coding
description:
  Alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.


ensembl_gene_id: Ssed_1319
symbol: csrA
gene_biotype: protein_coding
description:
  Carbon storage regulator, CsrA; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).


ensembl_gene_id: Ssed_1320
symbol: oadG
gene_biotype: protein_coding
description:
  Sodium pump decarboxylase, gamma subunit; Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.


ensembl_gene_id: Ssed_1322
symbol: Ssed_1322
gene_biotype: protein_coding
description:
  Glutaconyl-CoA decarboxylase; Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation; Belongs to the GcdB/MmdB/OadB family.


ensembl_gene_id: Ssed_1326
symbol: Ssed_1326
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_1224 sodium:dicarboxylate symporter; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: Ssed_1329
symbol: gshA
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_1227 glutamate--cysteine ligase; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.


ensembl_gene_id: Ssed_1333
symbol: purE
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazole carboxylase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).


ensembl_gene_id: Ssed_1335
symbol: Ssed_1335
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_1231 RNA polymerase, sigma-24 subunit, ECF subfamily; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: Ssed_1347
symbol: Ssed_1347
gene_biotype: protein_coding
description:
  KEGG: vfi:VFA0260 glutathione-regulated potassium-efflux system protein KefC; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.


ensembl_gene_id: Ssed_1352
symbol: psuG
gene_biotype: protein_coding
description:
  Indigoidine synthase A family protein; Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway; Belongs to the pseudouridine-5'-phosphate glycosidase family.


ensembl_gene_id: Ssed_1353
symbol: Ssed_1353
gene_biotype: protein_coding
description:
  KEGG: sde:Sde_3835 excitatory amino acid transporter; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: Ssed_1355
symbol: gltS
gene_biotype: protein_coding
description:
  Sodium-glutamate symporter; Catalyzes the sodium-dependent transport of glutamate. Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.


ensembl_gene_id: Ssed_1372
symbol: Ssed_1372
gene_biotype: protein_coding
description:
  Membrane-fusion protein-like protein; KEGG: rle:RL3775 putative HlyD family secretion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: Ssed_1383
symbol: Ssed_1383
gene_biotype: protein_coding
description:
  Response regulator containing a CheY-like protein receiver domain and a GGDEF domain-like protein; KEGG: dar:Daro_0012 response regulator receiver.


ensembl_gene_id: Ssed_1399
symbol: Ssed_1399
gene_biotype: protein_coding
description:
  KEGG: sfr:Sfri_2743 formate hydrogenlyase subunit 3/multisubunit Na+/H+ antiporter MnhD subunit-like protein.


ensembl_gene_id: Ssed_1401
symbol: Ssed_1401
gene_biotype: protein_coding
description:
  AraC-type DNA-binding domain-containing protein-like protein; KEGG: vvy:VVA1171 hypothetical protein.


ensembl_gene_id: Ssed_1407
symbol: smpB
gene_biotype: protein_coding
description:
  SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]


ensembl_gene_id: Ssed_1410
symbol: bamE
gene_biotype: protein_coding
description:
  SmpA/OmlA domain protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: Ssed_1429
symbol: rlmN
gene_biotype: protein_coding
description:
  Radical SAM enzyme, Cfr family; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family.


ensembl_gene_id: Ssed_1432
symbol: ispG
gene_biotype: protein_coding
description:
  4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family.


ensembl_gene_id: Ssed_1435
symbol: bamB
gene_biotype: protein_coding
description:
  Pyrrolo-quinoline quinone; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: Ssed_1436
symbol: der
gene_biotype: protein_coding
description:
  Small GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.


ensembl_gene_id: Ssed_1444
symbol: Ssed_1444
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_2585 histone family protein nucleoid-structuring protein H-NS; Belongs to the histone-like protein H-NS family.


ensembl_gene_id: Ssed_1461
symbol: Ssed_1461
gene_biotype: protein_coding
description:
  Phosphogluconate dehydrogenase (decarboxylating); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.


ensembl_gene_id: Ssed_1464
symbol: menA
gene_biotype: protein_coding
description:
  1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily.


ensembl_gene_id: Ssed_1465
symbol: Ssed_1465
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_2557 short-chain dehydrogenase/reductase SDR; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: Ssed_1472
symbol: metAS
gene_biotype: protein_coding
description:
  Homoserine O-succinyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine; Belongs to the MetA family.


ensembl_gene_id: Ssed_1473
symbol: Ssed_1473
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_1667 acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.


ensembl_gene_id: Ssed_1476
symbol: Ssed_1476
gene_biotype: protein_coding
description:
  KEGG: shm:Shewmr7_2661 enoyl-CoA hydratase/isomerase; Belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: Ssed_1479
symbol: Ssed_1479
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_1673 short-chain dehydrogenase/reductase SDR; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: Ssed_1487
symbol: Ssed_1487
gene_biotype: protein_coding
description:
  KEGG: ppr:PBPRB1458 putative NupC family protein (permease); Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.


ensembl_gene_id: Ssed_1491
symbol: Ssed_1491
gene_biotype: protein_coding
description:
  Conserved hypothetical ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.


ensembl_gene_id: Ssed_1503
symbol: pstB
gene_biotype: protein_coding
description:
  Phosphate ABC transporter, ATPase subunit; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.


ensembl_gene_id: Ssed_1505
symbol: Ssed_1505
gene_biotype: protein_coding
description:
  KEGG: shw:Sputw3181_2658 choline/carnitine/betaine transporter; Belongs to the BCCT transporter (TC 2.A.15) family.


ensembl_gene_id: Ssed_1532
symbol: Ssed_1532
gene_biotype: protein_coding
description:
  Ferrous iron transport protein B; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.


ensembl_gene_id: Ssed_1536
symbol: lpxH
gene_biotype: protein_coding
description:
  UDP-2,3-diacylglucosamine hydrolase; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: Ssed_1537
symbol: Ssed_1537
gene_biotype: protein_coding
description:
  Peptidylprolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.


ensembl_gene_id: Ssed_1538
symbol: cysS
gene_biotype: protein_coding
description:
  Cysteine--tRNA ligase; KEGG: slo:Shew_2511 cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: Ssed_1539
symbol: folD
gene_biotype: protein_coding
description:
  Methylenetetrahydrofolate dehydrogenase (NADP(+)); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.


ensembl_gene_id: Ssed_1540
symbol: tig
gene_biotype: protein_coding
description:
  Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.


ensembl_gene_id: Ssed_1541
symbol: clpP
gene_biotype: protein_coding
description:
  Endopeptidase Clp; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.


ensembl_gene_id: Ssed_1542
symbol: clpX
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.


ensembl_gene_id: Ssed_1543
symbol: lon
gene_biotype: protein_coding
description:
  Endopeptidase La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.


ensembl_gene_id: Ssed_1547
symbol: fabV
gene_biotype: protein_coding
description:
  Trans-2-enoyl-CoA reductase (NAD(+)); Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon- carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP); Belongs to the TER reductase family.


ensembl_gene_id: Ssed_1549
symbol: Ssed_1549
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_2501 oligopeptide/dipeptide ABC transporter, ATPase subunit; Belongs to the ABC transporter superfamily.


ensembl_gene_id: Ssed_1575
symbol: Ssed_1575
gene_biotype: protein_coding
description:
  TonB family protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.


ensembl_gene_id: Ssed_1584
symbol: Ssed_1584
gene_biotype: protein_coding
description:
  KEGG: son:SO2847 transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_1588
symbol: sbcD
gene_biotype: protein_coding
description:
  Nuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.


ensembl_gene_id: Ssed_1601
symbol: Ssed_1601
gene_biotype: protein_coding
description:
  Anaerobic ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.


ensembl_gene_id: Ssed_1603
symbol: ribA
gene_biotype: protein_coding
description:
  GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family.


ensembl_gene_id: Ssed_1605
symbol: Ssed_1605
gene_biotype: protein_coding
description:
  KEGG: cps:CPS_1457 transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_1614
symbol: Ssed_1614
gene_biotype: protein_coding
description:
  KEGG: sbl:Sbal_2775 acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: Ssed_1615
symbol: Ssed_1615
gene_biotype: protein_coding
description:
  KEGG: spc:Sputcn32_2473 efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: Ssed_1619
symbol: Ssed_1619
gene_biotype: protein_coding
description:
  Sodium/proline symporter; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: Ssed_1621
symbol: Ssed_1621
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_2433 RNA polymerase, sigma-24 subunit, ECF subfamily; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: Ssed_1629
symbol: fadJ
gene_biotype: protein_coding
description:
  Fatty acid oxidation complex, alpha subunit FadJ; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: Ssed_1637
symbol: prmB
gene_biotype: protein_coding
description:
  Site-specific DNA-methyltransferase (adenine-specific); Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue; Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.


ensembl_gene_id: Ssed_1638
symbol: aroC
gene_biotype: protein_coding
description:
  Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.


ensembl_gene_id: Ssed_1643
symbol: mnmC
gene_biotype: protein_coding
description:
  FAD dependent oxidoreductase; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family.


ensembl_gene_id: Ssed_1644
symbol: Ssed_1644
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_2410 beta-ketoacyl synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: Ssed_1647
symbol: Ssed_1647
gene_biotype: protein_coding
description:
  Protein-glutamate O-methyltransferase; KEGG: vvy:VVA0934 methylase of chemotaxis methyl-accepting protein.


ensembl_gene_id: Ssed_1649
symbol: pdxB
gene_biotype: protein_coding
description:
  D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate.


ensembl_gene_id: Ssed_1650
symbol: asd
gene_biotype: protein_coding
description:
  Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.


ensembl_gene_id: Ssed_1652
symbol: truA
gene_biotype: protein_coding
description:
  tRNA-pseudouridine synthase I; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.


ensembl_gene_id: Ssed_1653
symbol: Ssed_1653
gene_biotype: protein_coding
description:
  Dihydrofolate synthase; KEGG: she:Shewmr4_1427 FolC bifunctional protein; Belongs to the folylpolyglutamate synthase family.


ensembl_gene_id: Ssed_1656
symbol: purF
gene_biotype: protein_coding
description:
  Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.


ensembl_gene_id: Ssed_1658
symbol: topB
gene_biotype: protein_coding
description:
  DNA topoisomerase; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA superc [...]


ensembl_gene_id: Ssed_1670
symbol: Ssed_1670
gene_biotype: protein_coding
description:
  Intracellular septation protein A; Involved in cell division; probably involved in intracellular septation; Belongs to the YciB family.


ensembl_gene_id: Ssed_1671
symbol: Ssed_1671
gene_biotype: protein_coding
description:
  Type II secretory pathway component ExeA (predicted ATPase)-like protein; KEGG: slo:Shew_1009 peptidoglycan-binding domain 1 protein.


ensembl_gene_id: Ssed_1674
symbol: Ssed_1674
gene_biotype: protein_coding
description:
  Nickel-responsive regulator; Transcriptional regulator; Belongs to the transcriptional regulatory CopG/NikR family.


ensembl_gene_id: Ssed_1681
symbol: trpA
gene_biotype: protein_coding
description:
  Tryptophan synthase; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.


ensembl_gene_id: Ssed_1682
symbol: trpB
gene_biotype: protein_coding
description:
  Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.


ensembl_gene_id: Ssed_1683
symbol: trpC
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_2254 indole-3-glycerol-phosphate synthase., phosphoribosylanthranilate isomerase; Belongs to the TrpC family.


ensembl_gene_id: Ssed_1684
symbol: trpD
gene_biotype: protein_coding
description:
  Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).


ensembl_gene_id: Ssed_1689
symbol: Ssed_1689
gene_biotype: protein_coding
description:
  Chromosome segregation and condensation protein ScpA; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.


ensembl_gene_id: Ssed_1690
symbol: Ssed_1690
gene_biotype: protein_coding
description:
  Putative transcriptional regulator; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.


ensembl_gene_id: Ssed_1701
symbol: Ssed_1701
gene_biotype: protein_coding
description:
  KEGG: she:Shewmr4_1486 conserved hypothetical protein 95; Belongs to the methyltransferase superfamily.


ensembl_gene_id: Ssed_1704
symbol: Ssed_1704
gene_biotype: protein_coding
description:
  Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.


ensembl_gene_id: Ssed_1705
symbol: ackA
gene_biotype: protein_coding
description:
  Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.


ensembl_gene_id: Ssed_1707
symbol: Ssed_1707
gene_biotype: protein_coding
description:
  (Formate-C-acetyltransferase)-activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family.


ensembl_gene_id: Ssed_1712
symbol: Ssed_1712
gene_biotype: protein_coding
description:
  KEGG: shw:Sputw3181_1634 transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_1714
symbol: Ssed_1714
gene_biotype: protein_coding
description:
  KEGG: dps:DP0460 probable sodium/pantothenate symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: Ssed_1721
symbol: Ssed_1721
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_2382 cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family.


ensembl_gene_id: Ssed_1724
symbol: Ssed_1724
gene_biotype: protein_coding
description:
  KEGG: hch:HCH_02324 transcriptional regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_1727
symbol: Ssed_1727
gene_biotype: protein_coding
description:
  KEGG: pau:PA14_23540 putative transcriptional activator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_1734
symbol: cysZ
gene_biotype: protein_coding
description:
  Protein of unknown function DUF540; High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway; Belongs to the CysZ family.


ensembl_gene_id: Ssed_1737
symbol: zipA
gene_biotype: protein_coding
description:
  Cell division protein ZipA; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.


ensembl_gene_id: Ssed_1738
symbol: ligA
gene_biotype: protein_coding
description:
  DNA ligase (NAD(+)); DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.


ensembl_gene_id: Ssed_1746
symbol: Ssed_1746
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_2371 Na+/solute symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: Ssed_1749
symbol: Ssed_1749
gene_biotype: protein_coding
description:
  KEGG: maq:Maqu_0948 CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: Ssed_1756
symbol: Ssed_1756
gene_biotype: protein_coding
description:
  Pyridine nucleotide transhydrogenase subunit-alpha; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the AlaDH/PNT family.


ensembl_gene_id: Ssed_1757
symbol: Ssed_1757
gene_biotype: protein_coding
description:
  NAD(P)(+) transhydrogenase (AB-specific); The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.


ensembl_gene_id: Ssed_1758
symbol: fabH
gene_biotype: protein_coding
description:
  Beta-ketoacyl-acyl-carrier-protein synthase I; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.


ensembl_gene_id: Ssed_1762
symbol: Ssed_1762
gene_biotype: protein_coding
description:
  Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).


ensembl_gene_id: Ssed_1768
symbol: Ssed_1768
gene_biotype: protein_coding
description:
  Protein involved in meta-pathway of phenol degradation-like protein; KEGG: sat:SYN_00385 hypothetical protein.


ensembl_gene_id: Ssed_1774
symbol: Ssed_1774
gene_biotype: protein_coding
description:
  KEGG: ppr:PBPRB1741 hypothetical carnitine O-acyltransferase; Belongs to the carnitine/choline acetyltransferase family.


ensembl_gene_id: Ssed_1776
symbol: Ssed_1776
gene_biotype: protein_coding
description:
  KEGG: sit:TM1040_3283 transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_1781
symbol: Ssed_1781
gene_biotype: protein_coding
description:
  KEGG: saz:Sama_2082 signal transduction histidine kinase regulating C4-dicarboxylate transport system-like protein.


ensembl_gene_id: Ssed_1786
symbol: corA
gene_biotype: protein_coding
description:
  Magnesium and cobalt transport protein CorA; Mediates influx of magnesium ions. Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.


ensembl_gene_id: Ssed_1802
symbol: nadE
gene_biotype: protein_coding
description:
  NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.


ensembl_gene_id: Ssed_1817
symbol: Ssed_1817
gene_biotype: protein_coding
description:
  KEGG: pvi:Cvib_1366 SSS sodium solute transporter superfamily; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: Ssed_1824
symbol: Ssed_1824
gene_biotype: protein_coding
description:
  KEGG: shw:Sputw3181_1730 uncharacterized conserved protein UCP029143; Belongs to the UPF0267 family.


ensembl_gene_id: Ssed_1844
symbol: purN
gene_biotype: protein_coding
description:
  Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.


ensembl_gene_id: Ssed_1846
symbol: upp
gene_biotype: protein_coding
description:
  Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.


ensembl_gene_id: Ssed_1850
symbol: rnt
gene_biotype: protein_coding
description:
  Ribonuclease T; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.


ensembl_gene_id: Ssed_1854
symbol: tolQ
gene_biotype: protein_coding
description:
  MotA/TolQ/ExbB proton channel; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: Ssed_1855
symbol: tolR
gene_biotype: protein_coding
description:
  Biopolymer transport protein ExbD/TolR; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: Ssed_1857
symbol: tolB
gene_biotype: protein_coding
description:
  TolB, N-terminal domain protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: Ssed_1858
symbol: pal
gene_biotype: protein_coding
description:
  OmpA domain protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: Ssed_1859
symbol: cpoB
gene_biotype: protein_coding
description:
  Tetratricopeptide TPR_2 repeat protein; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family.


ensembl_gene_id: Ssed_1863
symbol: acsA
gene_biotype: protein_coding
description:
  acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.


ensembl_gene_id: Ssed_1870
symbol: Ssed_1870
gene_biotype: protein_coding
description:
  Protein of unknown function DUF299; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.


ensembl_gene_id: Ssed_1871
symbol: Ssed_1871
gene_biotype: protein_coding
description:
  Pyruvate, water dikinase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.


ensembl_gene_id: Ssed_1877
symbol: Ssed_1877
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_1555 Glu/Leu/Phe/Val dehydrogenase, dimerisation region; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.


ensembl_gene_id: Ssed_1879
symbol: Ssed_1879
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_1558 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.


ensembl_gene_id: Ssed_1881
symbol: mnmA
gene_biotype: protein_coding
description:
  tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.


ensembl_gene_id: Ssed_1882
symbol: Ssed_1882
gene_biotype: protein_coding
description:
  KEGG: she:Shewmr4_1605 pseudouridine synthase, Rsu; Belongs to the pseudouridine synthase RsuA family.


ensembl_gene_id: Ssed_1883
symbol: Ssed_1883
gene_biotype: protein_coding
description:
  KEGG: shm:Shewmr7_1681 isocitrate dehydrogenase, NADP-dependent; Belongs to the monomeric-type IDH family.


ensembl_gene_id: Ssed_1885
symbol: clpS
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease adaptor protein ClpS; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family.


ensembl_gene_id: Ssed_1886
symbol: Ssed_1886
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_1566 ATP-dependent Clp protease, ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family.


ensembl_gene_id: Ssed_1887
symbol: infA
gene_biotype: protein_coding
description:
  Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.


ensembl_gene_id: Ssed_1888
symbol: bpt
gene_biotype: protein_coding
description:
  Arginyltransferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate. Belongs to the R-transferase family. Bpt subfamily.


ensembl_gene_id: Ssed_1889
symbol: aat
gene_biotype: protein_coding
description:
  Leucyltransferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.


ensembl_gene_id: Ssed_1898
symbol: hypA
gene_biotype: protein_coding
description:
  Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.


ensembl_gene_id: Ssed_1903
symbol: Ssed_1903
gene_biotype: protein_coding
description:
  (NiFe) hydrogenase maturation protein HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.


ensembl_gene_id: Ssed_1907
symbol: Ssed_1907
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_1764 nickel-dependent hydrogenase, large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.


ensembl_gene_id: Ssed_1910
symbol: Ssed_1910
gene_biotype: protein_coding
description:
  KEGG: hch:HCH_06608 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain.


ensembl_gene_id: Ssed_1912
symbol: napD
gene_biotype: protein_coding
description:
  NapD protein; Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin- arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.


ensembl_gene_id: Ssed_1913
symbol: napA
gene_biotype: protein_coding
description:
  Anaerobic dehydrogenase, typically selenocysteine-containing; Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.


ensembl_gene_id: Ssed_1914
symbol: Ssed_1914
gene_biotype: protein_coding
description:
  Periplasmic nitrate reductase, cytochrome c-type protein; Electron transfer subunit of the periplasmic nitrate reductase complex NapAB; Belongs to the NapB family.


ensembl_gene_id: Ssed_1917
symbol: Ssed_1917
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_1773 transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_1919
symbol: Ssed_1919
gene_biotype: protein_coding
description:
  KEGG: hch:HCH_01467 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain.


ensembl_gene_id: Ssed_1931
symbol: hypA-2
gene_biotype: protein_coding
description:
  Hydrogenase nickel incorporation protein; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.


ensembl_gene_id: Ssed_1935
symbol: recD
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease V; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzy [...]


ensembl_gene_id: Ssed_1936
symbol: recB
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease V, beta subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and re [...]


ensembl_gene_id: Ssed_1937
symbol: recC
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease V, gamma subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and r [...]


ensembl_gene_id: Ssed_1954
symbol: Ssed_1954
gene_biotype: protein_coding
description:
  KEGG: psa:PST_0896 respiratory nitrate reductase alpha chain; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: Ssed_1975
symbol: Ssed_1975
gene_biotype: protein_coding
description:
  KEGG: pat:Patl_3597 acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: Ssed_1976
symbol: Ssed_1976
gene_biotype: protein_coding
description:
  KEGG: sfr:Sfri_3678 efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: Ssed_1981
symbol: msrP
gene_biotype: protein_coding
description:
  Twin-arginine translocation pathway signal; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to re [...]


ensembl_gene_id: Ssed_1982
symbol: msrQ
gene_biotype: protein_coding
description:
  Ferric reductase domain protein transmembrane component, N-terminal domain; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduct [...]


ensembl_gene_id: Ssed_1984
symbol: Ssed_1984
gene_biotype: protein_coding
description:
  Regulator of ribonuclease activity A; Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.


ensembl_gene_id: Ssed_1989
symbol: gloB
gene_biotype: protein_coding
description:
  Hydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.


ensembl_gene_id: Ssed_1991
symbol: Ssed_1991
gene_biotype: protein_coding
description:
  KEGG: shw:Sputw3181_2247 transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_1993
symbol: dnaQ
gene_biotype: protein_coding
description:
  DNA-directed DNA polymerase; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.


ensembl_gene_id: Ssed_1995
symbol: Ssed_1995
gene_biotype: protein_coding
description:
  Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.


ensembl_gene_id: Ssed_1996
symbol: Ssed_1996
gene_biotype: protein_coding
description:
  KEGG: aha:AHA_0957 HTH-type transcriptional regulator XapR; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_2013
symbol: thiC
gene_biotype: protein_coding
description:
  Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.


ensembl_gene_id: Ssed_2014
symbol: thiE
gene_biotype: protein_coding
description:
  Phosphomethylpyrimidine kinase, Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.


ensembl_gene_id: Ssed_2017
symbol: thiG
gene_biotype: protein_coding
description:
  Thiazole biosynthesis family protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.


ensembl_gene_id: Ssed_2021
symbol: Ssed_2021
gene_biotype: protein_coding
description:
  KEGG: sbl:Sbal_2030 transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_2027
symbol: cmoB
gene_biotype: protein_coding
description:
  Putative methyltransferase; Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L- methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5- carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.


ensembl_gene_id: Ssed_2028
symbol: cmoA
gene_biotype: protein_coding
description:
  Putative methyltransferase; Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).


ensembl_gene_id: Ssed_2030
symbol: aspS
gene_biotype: protein_coding
description:
  aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.


ensembl_gene_id: Ssed_2032
symbol: ruvC
gene_biotype: protein_coding
description:
  Crossover junction endodeoxyribonuclease; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.


ensembl_gene_id: Ssed_2033
symbol: ruvA
gene_biotype: protein_coding
description:
  Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.


ensembl_gene_id: Ssed_2034
symbol: ruvB
gene_biotype: protein_coding
description:
  Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.


ensembl_gene_id: Ssed_2038
symbol: nth
gene_biotype: protein_coding
description:
  DNA-(apurinic or apyrimidinic site) lyase; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.


ensembl_gene_id: Ssed_2039
symbol: rnfE
gene_biotype: protein_coding
description:
  Electron transport complex, RnfABCDGE type, E subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.


ensembl_gene_id: Ssed_2040
symbol: rnfG
gene_biotype: protein_coding
description:
  Electron transport complex, RnfABCDGE type, G subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the RnfG family.


ensembl_gene_id: Ssed_2041
symbol: rnfD
gene_biotype: protein_coding
description:
  Electron transport complex, RnfABCDGE type, D subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the NqrB/RnfD family.


ensembl_gene_id: Ssed_2042
symbol: rnfC
gene_biotype: protein_coding
description:
  Electron transport complex, RnfABCDGE type, C subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.


ensembl_gene_id: Ssed_2043
symbol: rnfB
gene_biotype: protein_coding
description:
  Electron transport complex, RnfABCDGE type, B subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.


ensembl_gene_id: Ssed_2044
symbol: rnfA
gene_biotype: protein_coding
description:
  Electron transport complex, RnfABCDGE type, A subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.


ensembl_gene_id: Ssed_2046
symbol: uvrB
gene_biotype: protein_coding
description:
  Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]


ensembl_gene_id: Ssed_2048
symbol: queC
gene_biotype: protein_coding
description:
  ExsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.


ensembl_gene_id: Ssed_2049
symbol: queE
gene_biotype: protein_coding
description:
  Radical activating enzyme; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.


ensembl_gene_id: Ssed_2070
symbol: zwf
gene_biotype: protein_coding
description:
  Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.


ensembl_gene_id: Ssed_2072
symbol: edd
gene_biotype: protein_coding
description:
  Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family.


ensembl_gene_id: Ssed_2080
symbol: cbiD
gene_biotype: protein_coding
description:
  Cobalamin biosynthesis protein; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.


ensembl_gene_id: Ssed_2085
symbol: Ssed_2085
gene_biotype: protein_coding
description:
  Cobalamin biosynthesis protein CbiK Co2+ chelatase-like protein; KEGG: pca:Pcar_0478 cobalt chelatase.


ensembl_gene_id: Ssed_2088
symbol: Ssed_2088
gene_biotype: protein_coding
description:
  Uroporphyrinogen-III methylase-like protein; KEGG: dps:DP1734 probable uroporphyrinogen III synthase/methyltransferase (HemD+CobA); Belongs to the precorrin methyltransferase family.


ensembl_gene_id: Ssed_2089
symbol: cobD
gene_biotype: protein_coding
description:
  cobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.


ensembl_gene_id: Ssed_2095
symbol: Ssed_2095
gene_biotype: protein_coding
description:
  ABC-type cobalt transport system permease component CbiQ and related transporter-like protein; KEGG: rpc:RPC_1961 cobalt ABC transporter CbiQ, permease subunit.


ensembl_gene_id: Ssed_2103
symbol: Ssed_2103
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; KEGG: deb:DehaBAV1_0988 4Fe-4S ferredoxin, iron-sulfur binding domain protein.


ensembl_gene_id: Ssed_2107
symbol: Ssed_2107
gene_biotype: protein_coding
description:
  ABC-type amino acid transport/signal transduction systems periplasmic component/domain-like protein; KEGG: cps:CPS_4645 hypothetical protein.


ensembl_gene_id: Ssed_2108
symbol: Ssed_2108
gene_biotype: protein_coding
description:
  Fructose-2 6-bisphosphatase-like protein; KEGG: sen:SACE_1433 probable phosphoglycerate mutase (phosphoglyceromutase).


ensembl_gene_id: Ssed_2111
symbol: prpB
gene_biotype: protein_coding
description:
  Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.


ensembl_gene_id: Ssed_2112
symbol: Ssed_2112
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_1821 2-methylcitrate synthase/citrate synthase II; Belongs to the citrate synthase family.


ensembl_gene_id: Ssed_2115
symbol: Ssed_2115
gene_biotype: protein_coding
description:
  KEGG: ppr:PBPRA1657 putative Uup, ATPase components of ABC transporters with duplicated ATPase domains.


ensembl_gene_id: Ssed_2120
symbol: thrS
gene_biotype: protein_coding
description:
  threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).


ensembl_gene_id: Ssed_2123
symbol: rplT
gene_biotype: protein_coding
description:
  Ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.


ensembl_gene_id: Ssed_2128
symbol: lolA
gene_biotype: protein_coding
description:
  Outer membrane lipoprotein carrier protein LolA; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).


ensembl_gene_id: Ssed_2130
symbol: crcB
gene_biotype: protein_coding
description:
  CrcB protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.


ensembl_gene_id: Ssed_2131
symbol: serS
gene_biotype: protein_coding
description:
  Serine--tRNA ligase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).


ensembl_gene_id: Ssed_2137
symbol: Ssed_2137
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_2013 transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_2146
symbol: Ssed_2146
gene_biotype: protein_coding
description:
  ABC-type Fe3+-hydroxamate transport system periplasmic component-like protein; KEGG: afu:AF1397m spermidine/putrescine ABC transporter, periplasmic spermidine/putrescine-binding protein (PotD).


ensembl_gene_id: Ssed_2154
symbol: Ssed_2154
gene_biotype: protein_coding
description:
  Cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.


ensembl_gene_id: Ssed_2155
symbol: cobS
gene_biotype: protein_coding
description:
  Cobalamin 5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.


ensembl_gene_id: Ssed_2157
symbol: cobQ
gene_biotype: protein_coding
description:
  Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.


ensembl_gene_id: Ssed_2160
symbol: Ssed_2160
gene_biotype: protein_coding
description:
  Cobinamide kinase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.


ensembl_gene_id: Ssed_2162
symbol: Ssed_2162
gene_biotype: protein_coding
description:
  Cobalbumin biosynthesis enzyme; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.


ensembl_gene_id: Ssed_2163
symbol: Ssed_2163
gene_biotype: protein_coding
description:
  KEGG: sdn:Sden_1117 transport system permease protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: Ssed_2166
symbol: Ssed_2166
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_2011 acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: Ssed_2167
symbol: Ssed_2167
gene_biotype: protein_coding
description:
  KEGG: sfr:Sfri_1930 efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: Ssed_2172
symbol: Ssed_2172
gene_biotype: protein_coding
description:
  KEGG: vvu:VV1_0390 SOS-response transcriptional repressor LexA -like protein; Belongs to the peptidase S24 family.


ensembl_gene_id: Ssed_2175
symbol: pdhA
gene_biotype: protein_coding
description:
  Pyruvate dehydrogenase (acetyl-transferring); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


ensembl_gene_id: Ssed_2176
symbol: Ssed_2176
gene_biotype: protein_coding
description:
  Pyruvate dehydrogenase complex, E1 beta2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.


ensembl_gene_id: Ssed_2211
symbol: Ssed_2211
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_1985 cytochrome c oxidase, cbb3-type, subunit I; Belongs to the heme-copper respiratory oxidase family.


ensembl_gene_id: Ssed_2214
symbol: Ssed_2214
gene_biotype: protein_coding
description:
  Cytochrome c oxidase, cbb3-type, subunit III; C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.


ensembl_gene_id: Ssed_2221
symbol: ttcA
gene_biotype: protein_coding
description:
  PP-loop domain protein; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.


ensembl_gene_id: Ssed_2224
symbol: Ssed_2224
gene_biotype: protein_coding
description:
  Protein of unknown function UPF0052 and CofD; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family.


ensembl_gene_id: Ssed_2226
symbol: Ssed_2226
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_2000 glyceraldehyde-3-phosphate dehydrogenase, type I; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.


ensembl_gene_id: Ssed_2228
symbol: Ssed_2228
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_2002 glyceraldehyde-3-phosphate dehydrogenase, type I; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.


ensembl_gene_id: Ssed_2230
symbol: Ssed_2230
gene_biotype: protein_coding
description:
  Bacterioferritin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family.


ensembl_gene_id: Ssed_2239
symbol: Ssed_2239
gene_biotype: protein_coding
description:
  KEGG: vfi:VF1658 short chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: Ssed_2247
symbol: Ssed_2247
gene_biotype: protein_coding
description:
  KEGG: msm:MSMEG_0277 putative aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: Ssed_2256
symbol: Ssed_2256
gene_biotype: protein_coding
description:
  Negative regulator of beta-lactamase expression-like protein; KEGG: sfv:SFV_0855 putative regulator.


ensembl_gene_id: Ssed_2280
symbol: Ssed_2280
gene_biotype: protein_coding
description:
  ApbE family lipoprotein; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. Belongs to the ApbE family.


ensembl_gene_id: Ssed_2285
symbol: Ssed_2285
gene_biotype: protein_coding
description:
  KEGG: she:Shewmr4_1939 efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: Ssed_2291
symbol: Ssed_2291
gene_biotype: protein_coding
description:
  Serine-type D-Ala-D-Ala carboxypeptidase; KEGG: spc:Sputcn32_2034 D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase.


ensembl_gene_id: Ssed_2294
symbol: pyrF
gene_biotype: protein_coding
description:
  Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.


ensembl_gene_id: Ssed_2295
symbol: lapB
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane; Belongs to the LapB family.


ensembl_gene_id: Ssed_2296
symbol: lapA
gene_biotype: protein_coding
description:
  Protein of unknown function DUF1049; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family.


ensembl_gene_id: Ssed_2297
symbol: ihfB
gene_biotype: protein_coding
description:
  Integration host factor, beta subunit; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.


ensembl_gene_id: Ssed_2298
symbol: Ssed_2298
gene_biotype: protein_coding
description:
  Ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.


ensembl_gene_id: Ssed_2300
symbol: aroA
gene_biotype: protein_coding
description:
  3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.


ensembl_gene_id: Ssed_2302
symbol: serC
gene_biotype: protein_coding
description:
  Phosphoserine transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.


ensembl_gene_id: Ssed_2304
symbol: ubiG
gene_biotype: protein_coding
description:
  3-demethylubiquinone-9 3-O-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family.


ensembl_gene_id: Ssed_2306
symbol: Ssed_2306
gene_biotype: protein_coding
description:
  Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.


ensembl_gene_id: Ssed_2320
symbol: clsA
gene_biotype: protein_coding
description:
  Putative cardiolipin synthase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.


ensembl_gene_id: Ssed_2326
symbol: nadA
gene_biotype: protein_coding
description:
  Methylated-DNA--(protein)-cysteine S-methyltransferase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate; Belongs to the quinolinate synthase A family. Type 1 subfamily.


ensembl_gene_id: Ssed_2327
symbol: Ssed_2327
gene_biotype: protein_coding
description:
  Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase; KEGG: sfr:Sfri_1937 catalytic domain of components of various dehydrogenase complexes.


ensembl_gene_id: Ssed_2330
symbol: astE
gene_biotype: protein_coding
description:
  Succinylglutamate desuccinylase/aspartoacylase; Transforms N(2)-succinylglutamate into succinate and glutamate; Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.


ensembl_gene_id: Ssed_2331
symbol: msrA
gene_biotype: protein_coding
description:
  Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.


ensembl_gene_id: Ssed_2333
symbol: seqA
gene_biotype: protein_coding
description:
  SeqA family protein; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated.


ensembl_gene_id: Ssed_2337
symbol: Ssed_2337
gene_biotype: protein_coding
description:
  Flavodoxin; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family.


ensembl_gene_id: Ssed_2339
symbol: efp
gene_biotype: protein_coding
description:
  Translation elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.


ensembl_gene_id: Ssed_2345
symbol: Ssed_2345
gene_biotype: protein_coding
description:
  5'-nucleotidase; Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates.


ensembl_gene_id: Ssed_2349
symbol: Ssed_2349
gene_biotype: protein_coding
description:
  KEGG: sfr:Sfri_1898 iron-containing alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.


ensembl_gene_id: Ssed_2351
symbol: glcB
gene_biotype: protein_coding
description:
  Malate synthase; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.


ensembl_gene_id: Ssed_2352
symbol: Ssed_2352
gene_biotype: protein_coding
description:
  KEGG: sfr:Sfri_3138 transcriptional regulator, LysR family protein; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_2358
symbol: Ssed_2358
gene_biotype: protein_coding
description:
  Hydrolyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.


ensembl_gene_id: Ssed_2371
symbol: Ssed_2371
gene_biotype: protein_coding
description:
  KEGG: vvy:VV2660 flp pilus assembly protein, secretin CpaC; Belongs to the bacterial secretin family.


ensembl_gene_id: Ssed_2386
symbol: Ssed_2386
gene_biotype: protein_coding
description:
  Flagellin-like protein; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.


ensembl_gene_id: Ssed_2390
symbol: Ssed_2390
gene_biotype: protein_coding
description:
  KEGG: she:Shewmr4_2131 Fmu (Sun) domain protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.


ensembl_gene_id: Ssed_2393
symbol: Ssed_2393
gene_biotype: protein_coding
description:
  KEGG: hch:HCH_06689 predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.


ensembl_gene_id: Ssed_2394
symbol: Ssed_2394
gene_biotype: protein_coding
description:
  Spermidine/putrescine-binding periplasmic protein; Required for the activity of the bacterial periplasmic transport system of putrescine; Belongs to the bacterial solute-binding protein PotD/PotF family.


ensembl_gene_id: Ssed_2404
symbol: Ssed_2404
gene_biotype: protein_coding
description:
  KEGG: csa:Csal_1188 transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_2406
symbol: Ssed_2406
gene_biotype: protein_coding
description:
  Putrescine-binding periplasmic protein precursor; Required for the activity of the bacterial periplasmic transport system of putrescine; Belongs to the bacterial solute-binding protein PotD/PotF family.


ensembl_gene_id: Ssed_2409
symbol: fusA
gene_biotype: protein_coding
description:
  Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...]


ensembl_gene_id: Ssed_2415
symbol: Ssed_2415
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).


ensembl_gene_id: Ssed_2418
symbol: dapE
gene_biotype: protein_coding
description:
  Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily.


ensembl_gene_id: Ssed_2421
symbol: Ssed_2421
gene_biotype: protein_coding
description:
  Carbonate dehydratase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family.


ensembl_gene_id: Ssed_2424
symbol: kdsB
gene_biotype: protein_coding
description:
  3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO8N (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in the Shewanella genus. Belongs to the KdsB family.


ensembl_gene_id: Ssed_2427
symbol: Ssed_2427
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_1852 acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: Ssed_2428
symbol: Ssed_2428
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_1851 efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: Ssed_2429
symbol: bamC
gene_biotype: protein_coding
description:
  NlpBDapX family lipoprotein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: Ssed_2434
symbol: Ssed_2434
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_1844 transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_2437
symbol: Ssed_2437
gene_biotype: protein_coding
description:
  Peptidase M48, Ste24p; Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.


ensembl_gene_id: Ssed_2444
symbol: Ssed_2444
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_1835 glutaredoxin-like protein; Belongs to the glutaredoxin family. Monothiol subfamily.


ensembl_gene_id: Ssed_2445
symbol: Ssed_2445
gene_biotype: protein_coding
description:
  Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.


ensembl_gene_id: Ssed_2449
symbol: rplY
gene_biotype: protein_coding
description:
  Ribosomal protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family.


ensembl_gene_id: Ssed_2453
symbol: Ssed_2453
gene_biotype: protein_coding
description:
  Glutamate-1-semialdehyde 2,1-aminomutase; KEGG: slo:Shew_1826 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: Ssed_2454
symbol: uvrC
gene_biotype: protein_coding
description:
  Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.


ensembl_gene_id: Ssed_2465
symbol: Ssed_2465
gene_biotype: protein_coding
description:
  KEGG: vpa:VP2136 putative pore-forming cytotoxin integrase; Belongs to the 'phage' integrase family.


ensembl_gene_id: Ssed_2468
symbol: fabA
gene_biotype: protein_coding
description:
  3-hydroxydecanoyl-(acyl-carrier-protein) dehydratase; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.


ensembl_gene_id: Ssed_2469
symbol: rmf
gene_biotype: protein_coding
description:
  Ribosome modulation factor; During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes); Belongs to the ribosome modulation factor family.


ensembl_gene_id: Ssed_2473
symbol: rlmL
gene_biotype: protein_coding
description:
  Putative RNA methylase; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family.


ensembl_gene_id: Ssed_2474
symbol: zapC
gene_biotype: protein_coding
description:
  Protein of unknown function DUF1379; Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ.


ensembl_gene_id: Ssed_2475
symbol: pyrD
gene_biotype: protein_coding
description:
  Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.


ensembl_gene_id: Ssed_2483
symbol: Ssed_2483
gene_biotype: protein_coding
description:
  C-terminal processing peptidase; KEGG: slo:Shew_1802 carboxyl-terminal protease; Belongs to the peptidase S41A family.


ensembl_gene_id: Ssed_2484
symbol: proQ
gene_biotype: protein_coding
description:
  ProQ activator of osmoprotectant transporter ProP; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities; Belongs to the ProQ family.


ensembl_gene_id: Ssed_2503
symbol: Ssed_2503
gene_biotype: protein_coding
description:
  KEGG: sbl:Sbal_3379 transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_2512
symbol: fadR
gene_biotype: protein_coding
description:
  Fatty acid responsive transcription factor FadR domain protein; Multifunctional regulator of fatty acid metabolism.


ensembl_gene_id: Ssed_2513
symbol: nhaB
gene_biotype: protein_coding
description:
  Na+/H+ antiporter NhaB; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.


ensembl_gene_id: Ssed_2514
symbol: dsbB
gene_biotype: protein_coding
description:
  Disulphide bond formation protein DsbB; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family.


ensembl_gene_id: Ssed_2519
symbol: minC
gene_biotype: protein_coding
description:
  Septum site-determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family.


ensembl_gene_id: Ssed_2521
symbol: minE
gene_biotype: protein_coding
description:
  Cell division topological specificity factor MinE; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.


ensembl_gene_id: Ssed_2522
symbol: rnd
gene_biotype: protein_coding
description:
  Ribonuclease D; Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides; Belongs to the RNase D family.


ensembl_gene_id: Ssed_2531
symbol: Ssed_2531
gene_biotype: protein_coding
description:
  KEGG: hch:HCH_06320 NAD-dependent aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: Ssed_2541
symbol: hisG
gene_biotype: protein_coding
description:
  ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily.


ensembl_gene_id: Ssed_2542
symbol: hisD
gene_biotype: protein_coding
description:
  Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.


ensembl_gene_id: Ssed_2543
symbol: hisC
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_2199 histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.


ensembl_gene_id: Ssed_2544
symbol: hisB
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_2200 histidinol-phosphatase; In the N-terminal section; belongs to the histidinol- phosphatase family.


ensembl_gene_id: Ssed_2545
symbol: hisH
gene_biotype: protein_coding
description:
  Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.


ensembl_gene_id: Ssed_2547
symbol: hisF
gene_biotype: protein_coding
description:
  Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.


ensembl_gene_id: Ssed_2548
symbol: hisI
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_2204 phosphoribosyl-AMP cyclohydrolase; In the N-terminal section; belongs to the PRA-CH family.


ensembl_gene_id: Ssed_2552
symbol: purC
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_2211 phosphoribosylaminoimidazolesuccinocarboxamide synthase; Belongs to the SAICAR synthetase family.


ensembl_gene_id: Ssed_2566
symbol: Ssed_2566
gene_biotype: protein_coding
description:
  KEGG: sfr:Sfri_0207 transcriptional regulator, LysR family protein; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_2586
symbol: Ssed_2586
gene_biotype: protein_coding
description:
  Carbonate dehydratase; KEGG: jan:Jann_1168 transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_2592
symbol: Ssed_2592
gene_biotype: protein_coding
description:
  KEGG: ppr:PBPRB1431 putative transcriptional regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_2595
symbol: lpxM
gene_biotype: protein_coding
description:
  Lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase; Catalyzes the transfer of myristate from myristoyl-acyl carrier protein (ACP) to Kdo(2)-(lauroyl)-lipid IV(A) to form Kdo(2)- lipid A.


ensembl_gene_id: Ssed_2596
symbol: ihfA
gene_biotype: protein_coding
description:
  Integration host factor, alpha subunit; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.


ensembl_gene_id: Ssed_2598
symbol: pheS
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_2216 phenylalanyl-tRNA synthetase, alpha subunit; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.


ensembl_gene_id: Ssed_2606
symbol: pdxH
gene_biotype: protein_coding
description:
  Pyridoxal 5'-phosphate synthase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).


ensembl_gene_id: Ssed_2618
symbol: cdd
gene_biotype: protein_coding
description:
  Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.


ensembl_gene_id: Ssed_2622
symbol: Ssed_2622
gene_biotype: protein_coding
description:
  3-oxoacyl-(acyl-carrier-protein) synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.


ensembl_gene_id: Ssed_2624
symbol: Ssed_2624
gene_biotype: protein_coding
description:
  3-oxoacyl-(acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: Ssed_2627
symbol: plsX
gene_biotype: protein_coding
description:
  Fatty acid/phospholipid synthesis protein PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.


ensembl_gene_id: Ssed_2630
symbol: Ssed_2630
gene_biotype: protein_coding
description:
  Maf protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes 7- methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids; Belongs to the Maf family. YceF subfamily.


ensembl_gene_id: Ssed_2633
symbol: Ssed_2633
gene_biotype: protein_coding
description:
  Lysozyme; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.


ensembl_gene_id: Ssed_2634
symbol: rne
gene_biotype: protein_coding
description:
  Ribonuclease, Rne/Rng family; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily.


ensembl_gene_id: Ssed_2637
symbol: Ssed_2637
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_1590 2OG-Fe(II) oxygenase; Belongs to the iron/ascorbate-dependent oxidoreductase family.


ensembl_gene_id: Ssed_2638
symbol: Ssed_2638
gene_biotype: protein_coding
description:
  GTP-binding protein, HSR1-related; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.


ensembl_gene_id: Ssed_2640
symbol: Ssed_2640
gene_biotype: protein_coding
description:
  Diacylglycerol kinase; Recycling of diacylglycerol produced during the turnover of membrane phospholipid.


ensembl_gene_id: Ssed_2644
symbol: rsmF
gene_biotype: protein_coding
description:
  Putative RNA methylase, NOL1/NOP2/sun family; Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA.


ensembl_gene_id: Ssed_2648
symbol: tmk
gene_biotype: protein_coding
description:
  dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.


ensembl_gene_id: Ssed_2649
symbol: mltG
gene_biotype: protein_coding
description:
  Aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.


ensembl_gene_id: Ssed_2652
symbol: Ssed_2652
gene_biotype: protein_coding
description:
  ATP-binding protein, Mrp/Nbp35 family; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.


ensembl_gene_id: Ssed_2653
symbol: metG
gene_biotype: protein_coding
description:
  Methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.


ensembl_gene_id: Ssed_2668
symbol: Ssed_2668
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_2134 heat shock protein HSP20; Belongs to the small heat shock protein (HSP20) family.


ensembl_gene_id: Ssed_2686
symbol: Ssed_2686
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_2153 transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_2701
symbol: Ssed_2701
gene_biotype: protein_coding
description:
  Anaerobic C4-dicarboxylate transporter; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane; Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.


ensembl_gene_id: Ssed_2704
symbol: Ssed_2704
gene_biotype: protein_coding
description:
  KEGG: maq:Maqu_0074 initiation factor 2B related; Belongs to the eIF-2B alpha/beta/delta subunits family.


ensembl_gene_id: Ssed_2705
symbol: Ssed_2705
gene_biotype: protein_coding
description:
  KEGG: reu:Reut_B5117 regulatory protein, LysR:LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_2715
symbol: Ssed_2715
gene_biotype: protein_coding
description:
  Adenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.


ensembl_gene_id: Ssed_2765
symbol: Ssed_2765
gene_biotype: protein_coding
description:
  KEGG: sfr:Sfri_1509 nitrite reductase (NAD(P)H), large subunit; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.


ensembl_gene_id: Ssed_2766
symbol: Ssed_2766
gene_biotype: protein_coding
description:
  Response regulator with putative antiterminator output domain-like protein; KEGG: sfr:Sfri_1508 response regulator receiver and ANTAR domain protein.


ensembl_gene_id: Ssed_2771
symbol: pepE
gene_biotype: protein_coding
description:
  Dipeptidase E; Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids.


ensembl_gene_id: Ssed_2773
symbol: bioD
gene_biotype: protein_coding
description:
  Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.


ensembl_gene_id: Ssed_2776
symbol: bioB
gene_biotype: protein_coding
description:
  Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.


ensembl_gene_id: Ssed_2777
symbol: Ssed_2777
gene_biotype: protein_coding
description:
  KEGG: sfr:Sfri_1474 adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: Ssed_2799
symbol: Ssed_2799
gene_biotype: protein_coding
description:
  KEGG: sde:Sde_2353 nitrate reductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.


ensembl_gene_id: Ssed_2809
symbol: cobB
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_1662 silent information regulator protein Sir2; Belongs to the sirtuin family. Class III subfamily.


ensembl_gene_id: Ssed_2811
symbol: sucD
gene_biotype: protein_coding
description:
  succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.


ensembl_gene_id: Ssed_2812
symbol: sucC
gene_biotype: protein_coding
description:
  Succinate--CoA ligase (ADP-forming); Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.


ensembl_gene_id: Ssed_2813
symbol: Ssed_2813
gene_biotype: protein_coding
description:
  2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).


ensembl_gene_id: Ssed_2815
symbol: Ssed_2815
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_1654 succinate dehydrogenase and fumarate reductase iron-sulfur protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.


ensembl_gene_id: Ssed_2816
symbol: Ssed_2816
gene_biotype: protein_coding
description:
  KEGG: son:SO1928 succinate dehydrogenase flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.


ensembl_gene_id: Ssed_2817
symbol: Ssed_2817
gene_biotype: protein_coding
description:
  Conserved hypothetical succinate dehydrogenase, hydrophobic subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH).


ensembl_gene_id: Ssed_2820
symbol: Ssed_2820
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_1649 efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: Ssed_2821
symbol: Ssed_2821
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_1648 acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: Ssed_2822
symbol: Ssed_2822
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_1647 acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: Ssed_2825
symbol: lpxK
gene_biotype: protein_coding
description:
  Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).


ensembl_gene_id: Ssed_2826
symbol: msbA
gene_biotype: protein_coding
description:
  ABC transporter, ATP-binding protein MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.


ensembl_gene_id: Ssed_2830
symbol: lolD
gene_biotype: protein_coding
description:
  Lipoprotein releasing system, ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.


ensembl_gene_id: Ssed_2833
symbol: mfd
gene_biotype: protein_coding
description:
  Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.


ensembl_gene_id: Ssed_2837
symbol: nagZ
gene_biotype: protein_coding
description:
  Beta-hexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.


ensembl_gene_id: Ssed_2838
symbol: Ssed_2838
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_1625 L-serine dehydratase 1; Belongs to the iron-sulfur dependent L-serine dehydratase family.


ensembl_gene_id: Ssed_2839
symbol: Ssed_2839
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_1624 transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_2842
symbol: astB
gene_biotype: protein_coding
description:
  Succinylarginine dihydrolase; Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)- succinylornithine, ammonia and CO(2).


ensembl_gene_id: Ssed_2844
symbol: Ssed_2844
gene_biotype: protein_coding
description:
  KEGG: sbl:Sbal_2499 sodium:dicarboxylate symporter; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: Ssed_2847
symbol: adk-2
gene_biotype: protein_coding
description:
  Nucleoside-triphosphate--adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.


ensembl_gene_id: Ssed_2850
symbol: recR
gene_biotype: protein_coding
description:
  Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.


ensembl_gene_id: Ssed_2851
symbol: Ssed_2851
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.


ensembl_gene_id: Ssed_2853
symbol: apt
gene_biotype: protein_coding
description:
  Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.


ensembl_gene_id: Ssed_2859
symbol: dusC
gene_biotype: protein_coding
description:
  Dihydrouridine synthase, DuS; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs. Belongs to the Dus family. DusC subfamily.


ensembl_gene_id: Ssed_2862
symbol: ndk
gene_biotype: protein_coding
description:
  Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.


ensembl_gene_id: Ssed_2865
symbol: Ssed_2865
gene_biotype: protein_coding
description:
  Signal transduction histidine kinase-like protein; KEGG: mgm:Mmc1_3164 multi-sensor hybrid histidine kinase.


ensembl_gene_id: Ssed_2867
symbol: hscA
gene_biotype: protein_coding
description:
  2-alkenal reductase; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.


ensembl_gene_id: Ssed_2868
symbol: hscB
gene_biotype: protein_coding
description:
  Co-chaperone Hsc20; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family.


ensembl_gene_id: Ssed_2869
symbol: Ssed_2869
gene_biotype: protein_coding
description:
  Iron-sulfur cluster assembly protein IscA; Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system; Belongs to the HesB/IscA family.


ensembl_gene_id: Ssed_2870
symbol: Ssed_2870
gene_biotype: protein_coding
description:
  FeS cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.


ensembl_gene_id: Ssed_2871
symbol: iscS
gene_biotype: protein_coding
description:
  Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.


ensembl_gene_id: Ssed_2872
symbol: Ssed_2872
gene_biotype: protein_coding
description:
  Transcriptional regulator, BadM/Rrf2 family; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.


ensembl_gene_id: Ssed_2874
symbol: trmJ
gene_biotype: protein_coding
description:
  RNA methyltransferase, TrmH family, group 1; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.


ensembl_gene_id: Ssed_2889
symbol: secF
gene_biotype: protein_coding
description:
  Protein-export membrane protein SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.


ensembl_gene_id: Ssed_2890
symbol: secD
gene_biotype: protein_coding
description:
  Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.


ensembl_gene_id: Ssed_2891
symbol: yajC
gene_biotype: protein_coding
description:
  Preprotein translocase, YajC subunit; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.


ensembl_gene_id: Ssed_2892
symbol: tgt
gene_biotype: protein_coding
description:
  Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form th [...]


ensembl_gene_id: Ssed_2893
symbol: queA
gene_biotype: protein_coding
description:
  S-adenosylmethionine--tRNA-ribosyltransferase- isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).


ensembl_gene_id: Ssed_2896
symbol: Ssed_2896
gene_biotype: protein_coding
description:
  Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.


ensembl_gene_id: Ssed_2898
symbol: sstT
gene_biotype: protein_coding
description:
  Sodium:dicarboxylate symporter; Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system). Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: Ssed_2903
symbol: Ssed_2903
gene_biotype: protein_coding
description:
  Methylated-DNA--(protein)-cysteine S-methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.


ensembl_gene_id: Ssed_2906
symbol: gltX
gene_biotype: protein_coding
description:
  glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).


ensembl_gene_id: Ssed_2914
symbol: Ssed_2914
gene_biotype: protein_coding
description:
  KEGG: sbl:Sbal_2815 transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_2915
symbol: Ssed_2915
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_3565 acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: Ssed_2932
symbol: Ssed_2932
gene_biotype: protein_coding
description:
  KEGG: shn:Shewana3_2783 UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family.


ensembl_gene_id: Ssed_2933
symbol: napF
gene_biotype: protein_coding
description:
  Ferredoxin-type protein NapF; Could be involved in the maturation of NapA, the catalytic subunit of the periplasmic nitrate reductase, before its export into the periplasm; Belongs to the NapF family.


ensembl_gene_id: Ssed_2955
symbol: Ssed_2955
gene_biotype: protein_coding
description:
  Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.


ensembl_gene_id: Ssed_2960
symbol: cysN
gene_biotype: protein_coding
description:
  Sulfate adenylyltransferase; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.


ensembl_gene_id: Ssed_2965
symbol: Ssed_2965
gene_biotype: protein_coding
description:
  KEGG: pgi:PG0119 glycosyl transferase, WecB/TagA/CpsF family; Belongs to the glycosyltransferase 26 family.


ensembl_gene_id: Ssed_2966
symbol: Ssed_2966
gene_biotype: protein_coding
description:
  KEGG: eca:ECA4208 UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family.


ensembl_gene_id: Ssed_2967
symbol: Ssed_2967
gene_biotype: protein_coding
description:
  KEGG: tdn:Tmden_1418 UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family.


ensembl_gene_id: Ssed_2968
symbol: Ssed_2968
gene_biotype: protein_coding
description:
  Acetyltransferase (isoleucine patch superfamily)-like protein; KEGG: acb:A1S_0057 capsular polysaccharide synthesis enzyme.


ensembl_gene_id: Ssed_2969
symbol: Ssed_2969
gene_biotype: protein_coding
description:
  Membrane protein involved in the export of O-antigen and teichoic acid-like protein; KEGG: mxa:MXAN_3260 hypothetical protein.


ensembl_gene_id: Ssed_2973
symbol: Ssed_2973
gene_biotype: protein_coding
description:
  KEGG: saz:Sama_2260 UDP-glucose/GDP-mannose dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.


ensembl_gene_id: Ssed_2990
symbol: Ssed_2990
gene_biotype: protein_coding
description:
  KEGG: vfi:VF0166 dTDP-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.


ensembl_gene_id: Ssed_3003
symbol: Ssed_3003
gene_biotype: protein_coding
description:
  Pyridoxal phosphate-dependent enzyme; Apparently involved in regulation of cell wall biogenesis-like protein; KEGG: rsq:Rsph17025_3841 hypothetical protein; Belongs to the DegT/DnrJ/EryC1 family.


ensembl_gene_id: Ssed_3015
symbol: Ssed_3015
gene_biotype: protein_coding
description:
  ABC-type polysaccharide/polyol phosphate export systems permease component-like protein; KEGG: maq:Maqu_2634 ABC-2 type transporter.


ensembl_gene_id: Ssed_3020
symbol: Ssed_3020
gene_biotype: protein_coding
description:
  Type II secretory pathway component PulD-like protein; KEGG: pat:Patl_3236 type II and III secretion system protein; Belongs to the bacterial secretin family.


ensembl_gene_id: Ssed_3024
symbol: Ssed_3024
gene_biotype: protein_coding
description:
  Type II secretory pathway component PulK-like protein; KEGG: sat:SYN_00453 general secretion pathway protein K.


ensembl_gene_id: Ssed_3031
symbol: wecA
gene_biotype: protein_coding
description:
  Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase; Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP-C55). Belongs to the glycosyltransferase 4 family. WecA subfamily.


ensembl_gene_id: Ssed_3033
symbol: rfaH
gene_biotype: protein_coding
description:
  NusG antitermination factor; Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components. Belongs to the RfaH family.


ensembl_gene_id: Ssed_3047
symbol: Ssed_3047
gene_biotype: protein_coding
description:
  Chemotaxis phosphatase, CheZ; Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).


ensembl_gene_id: Ssed_3049
symbol: fliA
gene_biotype: protein_coding
description:
  Phosphatidylserine decarboxylase; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily.


ensembl_gene_id: Ssed_3059
symbol: Ssed_3059
gene_biotype: protein_coding
description:
  Flagellar motor switch protein FliM; FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.


ensembl_gene_id: Ssed_3065
symbol: Ssed_3065
gene_biotype: protein_coding
description:
  Flagellar motor switch protein FliG; FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.


ensembl_gene_id: Ssed_3075
symbol: Ssed_3075
gene_biotype: protein_coding
description:
  Flagellin; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.


ensembl_gene_id: Ssed_3078
symbol: Ssed_3078
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_1354 flagellar hook-associated protein FlgK; Belongs to the flagella basal body rod proteins family.


ensembl_gene_id: Ssed_3082
symbol: Ssed_3082
gene_biotype: protein_coding
description:
  KEGG: sbl:Sbal_2942 flagellar basal-body rod protein FlgG; Belongs to the flagella basal body rod proteins family.


ensembl_gene_id: Ssed_3083
symbol: Ssed_3083
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_1349 flagellar basal-body rod protein FlgF; Belongs to the flagella basal body rod proteins family.


ensembl_gene_id: Ssed_3086
symbol: Ssed_3086
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_1346 flagellar basal-body rod protein FlgC; Belongs to the flagella basal body rod proteins family.


ensembl_gene_id: Ssed_3112
symbol: Ssed_3112
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_1312 efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: Ssed_3113
symbol: Ssed_3113
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_1311 acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: Ssed_3119
symbol: purL
gene_biotype: protein_coding
description:
  Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.


ensembl_gene_id: Ssed_3120
symbol: mltF
gene_biotype: protein_coding
description:
  Lytic transglycosylase, catalytic; Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella. In the N-terminal section; belongs to the bacterial solute- binding protein 3 family.


ensembl_gene_id: Ssed_3121
symbol: tadA
gene_biotype: protein_coding
description:
  Cytidine/deoxycytidylate deaminase family protein; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.


ensembl_gene_id: Ssed_3124
symbol: guaB
gene_biotype: protein_coding
description:
  Malate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.


ensembl_gene_id: Ssed_3125
symbol: xseA
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease VII; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family.


ensembl_gene_id: Ssed_3130
symbol: proS
gene_biotype: protein_coding
description:
  prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...]


ensembl_gene_id: Ssed_3134
symbol: Ssed_3134
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_2608 inner-membrane translocator; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: Ssed_3135
symbol: Ssed_3135
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_2609 inner-membrane translocator; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: Ssed_3143
symbol: Ssed_3143
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_2617 potassium efflux system protein; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.


ensembl_gene_id: Ssed_3145
symbol: tilS
gene_biotype: protein_coding
description:
  tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.


ensembl_gene_id: Ssed_3147
symbol: rnhB
gene_biotype: protein_coding
description:
  Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.


ensembl_gene_id: Ssed_3148
symbol: lpxB
gene_biotype: protein_coding
description:
  Lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: Ssed_3149
symbol: lpxA
gene_biotype: protein_coding
description:
  Acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: Ssed_3150
symbol: fabZ
gene_biotype: protein_coding
description:
  Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.


ensembl_gene_id: Ssed_3151
symbol: lpxD
gene_biotype: protein_coding
description:
  UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily.


ensembl_gene_id: Ssed_3153
symbol: bamA
gene_biotype: protein_coding
description:
  Surface antigen (D15); Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: Ssed_3155
symbol: dxr
gene_biotype: protein_coding
description:
  1-deoxy-D-xylulose-5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family.


ensembl_gene_id: Ssed_3157
symbol: uppS
gene_biotype: protein_coding
description:
  Di-trans, poly-cis-decaprenylcistransferase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.


ensembl_gene_id: Ssed_3158
symbol: frr
gene_biotype: protein_coding
description:
  Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.


ensembl_gene_id: Ssed_3160
symbol: tsf
gene_biotype: protein_coding
description:
  Translation elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.


ensembl_gene_id: Ssed_3162
symbol: map
gene_biotype: protein_coding
description:
  Methionine aminopeptidase, type I; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.


ensembl_gene_id: Ssed_3163
symbol: glnD
gene_biotype: protein_coding
description:
  (Protein-PII) uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.


ensembl_gene_id: Ssed_3164
symbol: dapD
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_2638 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family.


ensembl_gene_id: Ssed_3166
symbol: purU
gene_biotype: protein_coding
description:
  Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).


ensembl_gene_id: Ssed_3178
symbol: syd
gene_biotype: protein_coding
description:
  Syd family protein; Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function. Belongs to the Syd family.


ensembl_gene_id: Ssed_3179
symbol: queF
gene_biotype: protein_coding
description:
  GTP cyclohydrolase I; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).


ensembl_gene_id: Ssed_3182
symbol: Ssed_3182
gene_biotype: protein_coding
description:
  KEGG: son:SO1607 transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_3183
symbol: Ssed_3183
gene_biotype: protein_coding
description:
  KEGG: sbl:Sbal_1430 transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_3186
symbol: Ssed_3186
gene_biotype: protein_coding
description:
  KEGG: sfr:Sfri_1245 4'-phosphopantetheinyl transferase; Belongs to the P-Pant transferase superfamily.


ensembl_gene_id: Ssed_3204
symbol: Ssed_3204
gene_biotype: protein_coding
description:
  KEGG: ppr:PBPRA1458 omega-3 polyunsaturated fatty acid synthase PfaC; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: Ssed_3213
symbol: Ssed_3213
gene_biotype: protein_coding
description:
  KEGG: vpa:VPA0363 putative efflux protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: Ssed_3214
symbol: Ssed_3214
gene_biotype: protein_coding
description:
  KEGG: vpa:VPA0364 putative efflux protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: Ssed_3215
symbol: Ssed_3215
gene_biotype: protein_coding
description:
  KEGG: vpa:VPA0365 putative transcriptional regulator protein; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_3221
symbol: Ssed_3221
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_2670 transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_3224
symbol: Ssed_3224
gene_biotype: protein_coding
description:
  3-alpha,7-alpha, 12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoAhydratase; KEGG: drm:Dred_0577 MaoC domain protein dehydratase.


ensembl_gene_id: Ssed_3225
symbol: Ssed_3225
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_2672 enoyl-CoA hydratase/isomerase; Belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: Ssed_3227
symbol: Ssed_3227
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_2674 L-carnitine dehydratase/bile acid-inducible protein F; Belongs to the CoA-transferase III family.


ensembl_gene_id: Ssed_3229
symbol: Ssed_3229
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_2676 choline/carnitine/betaine transporter; Belongs to the BCCT transporter (TC 2.A.15) family.


ensembl_gene_id: Ssed_3232
symbol: Ssed_3232
gene_biotype: protein_coding
description:
  FAD dependent oxidoreductase; Part of an electron transfer system. Belongs to the ETF-QO/FixC family.


ensembl_gene_id: Ssed_3240
symbol: Ssed_3240
gene_biotype: protein_coding
description:
  KEGG: vvu:VV2_0173 transcriptional regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_3241
symbol: Ssed_3241
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.


ensembl_gene_id: Ssed_3253
symbol: Ssed_3253
gene_biotype: protein_coding
description:
  KEGG: hch:HCH_05115 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain.


ensembl_gene_id: Ssed_3265
symbol: Ssed_3265
gene_biotype: protein_coding
description:
  KEGG: ppr:PBPRB1023 hypothetical ribosomal small subunit pseudouridine synthase A; Belongs to the pseudouridine synthase RsuA family.


ensembl_gene_id: Ssed_3267
symbol: Ssed_3267
gene_biotype: protein_coding
description:
  4Fe-4S ferredoxin, iron-sulfur binding domain protein; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.


ensembl_gene_id: Ssed_3269
symbol: Ssed_3269
gene_biotype: protein_coding
description:
  Response regulator containing a CheY-like protein receiver domain and an HD-GYP domain-like protein; KEGG: gme:Gmet_0018 metal dependent phosphohydrolase.


ensembl_gene_id: Ssed_3289
symbol: Ssed_3289
gene_biotype: protein_coding
description:
  FOG: PKD repeat containing protein-like protein; KEGG: rme:Rmet_4552 curculin-like (mannose-binding) lectin.


ensembl_gene_id: Ssed_3293
symbol: Ssed_3293
gene_biotype: protein_coding
description:
  KEGG: hch:HCH_03521 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain.


ensembl_gene_id: Ssed_3295
symbol: Ssed_3295
gene_biotype: protein_coding
description:
  KEGG: shn:Shewana3_2867 Fmu (Sun) domain protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.


ensembl_gene_id: Ssed_3311
symbol: xni
gene_biotype: protein_coding
description:
  5'-3' exonuclease; Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.


ensembl_gene_id: Ssed_3319
symbol: rlmM
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.


ensembl_gene_id: Ssed_3322
symbol: Ssed_3322
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_2764 transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_3324
symbol: thiI
gene_biotype: protein_coding
description:
  Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.


ensembl_gene_id: Ssed_3327
symbol: xseB
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease VII, small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.


ensembl_gene_id: Ssed_3329
symbol: dxs
gene_biotype: protein_coding
description:
  Deoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.


ensembl_gene_id: Ssed_3330
symbol: grpE
gene_biotype: protein_coding
description:
  GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]


ensembl_gene_id: Ssed_3331
symbol: nadK
gene_biotype: protein_coding
description:
  NAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.


ensembl_gene_id: Ssed_3344
symbol: Ssed_3344
gene_biotype: protein_coding
description:
  Signal transduction protein containing a membrane domain an EAL and a GGDEF domain-like protein; KEGG: aeh:Mlg_0074 diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s).


ensembl_gene_id: Ssed_3359
symbol: Ssed_3359
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_2797 trimethylamine-N-oxide reductase C-type cytochrome TorC; Belongs to the TorC/TorY family.


ensembl_gene_id: Ssed_3360
symbol: Ssed_3360
gene_biotype: protein_coding
description:
  KEGG: sfr:Sfri_1994 trimethylamine-N-oxide reductase TorA; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: Ssed_3361
symbol: torD
gene_biotype: protein_coding
description:
  Cytoplasmic chaperone TorD family protein; Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor; Belongs to the TorD/DmsD family. TorD subfamily.


ensembl_gene_id: Ssed_3368
symbol: Ssed_3368
gene_biotype: protein_coding
description:
  Type IV pilus assembly PilZ; Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second-messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a possible effector protein.


ensembl_gene_id: Ssed_3370
symbol: Ssed_3370
gene_biotype: protein_coding
description:
  Methylated-DNA--(protein)-cysteine S-methyltransferase; KEGG: slo:Shew_2807 DNA repair protein RadA.


ensembl_gene_id: Ssed_3376
symbol: deoB
gene_biotype: protein_coding
description:
  Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family.


ensembl_gene_id: Ssed_3377
symbol: deoA
gene_biotype: protein_coding
description:
  Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.


ensembl_gene_id: Ssed_3378
symbol: deoC
gene_biotype: protein_coding
description:
  Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily.


ensembl_gene_id: Ssed_3380
symbol: Ssed_3380
gene_biotype: protein_coding
description:
  KEGG: shw:Sputw3181_1187 nucleoside transporter; Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.


ensembl_gene_id: Ssed_3382
symbol: prfC
gene_biotype: protein_coding
description:
  Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.


ensembl_gene_id: Ssed_3384
symbol: pnp
gene_biotype: protein_coding
description:
  Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.


ensembl_gene_id: Ssed_3386
symbol: rpsO
gene_biotype: protein_coding
description:
  Ribosomal protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.


ensembl_gene_id: Ssed_3387
symbol: truB
gene_biotype: protein_coding
description:
  tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.


ensembl_gene_id: Ssed_3388
symbol: rbfA
gene_biotype: protein_coding
description:
  Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.


ensembl_gene_id: Ssed_3389
symbol: infB
gene_biotype: protein_coding
description:
  Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.


ensembl_gene_id: Ssed_3391
symbol: rimP
gene_biotype: protein_coding
description:
  Protein of unknown function DUF150; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.


ensembl_gene_id: Ssed_3392
symbol: Ssed_3392
gene_biotype: protein_coding
description:
  Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.


ensembl_gene_id: Ssed_3393
symbol: tpiA
gene_biotype: protein_coding
description:
  Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.


ensembl_gene_id: Ssed_3394
symbol: glmM
gene_biotype: protein_coding
description:
  Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.


ensembl_gene_id: Ssed_3395
symbol: Ssed_3395
gene_biotype: protein_coding
description:
  Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.


ensembl_gene_id: Ssed_3396
symbol: ftsH
gene_biotype: protein_coding
description:
  Microtubule-severing ATPase; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family.  In the central section; belongs to the AAA ATPase family.


ensembl_gene_id: Ssed_3397
symbol: rlmE
gene_biotype: protein_coding
description:
  Ribosomal RNA methyltransferase RrmJ/FtsJ; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.


ensembl_gene_id: Ssed_3402
symbol: greA
gene_biotype: protein_coding
description:
  Transcription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.


ensembl_gene_id: Ssed_3405
symbol: dapB
gene_biotype: protein_coding
description:
  Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.


ensembl_gene_id: Ssed_3408
symbol: dnaJ
gene_biotype: protein_coding
description:
  Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]


ensembl_gene_id: Ssed_3415
symbol: proA
gene_biotype: protein_coding
description:
  Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.


ensembl_gene_id: Ssed_3416
symbol: proB
gene_biotype: protein_coding
description:
  Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.


ensembl_gene_id: Ssed_3420
symbol: Ssed_3420
gene_biotype: protein_coding
description:
  KEGG: she:Shewmr4_0949 peptidase M17, leucyl aminopeptidase domain protein; Belongs to the peptidase M17 family.


ensembl_gene_id: Ssed_3422
symbol: dinB
gene_biotype: protein_coding
description:
  DNA-directed DNA polymerase; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.


ensembl_gene_id: Ssed_3426
symbol: nqrF
gene_biotype: protein_coding
description:
  NADH:ubiquinone oxidoreductase, subunit F; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.


ensembl_gene_id: Ssed_3427
symbol: nqrE
gene_biotype: protein_coding
description:
  NADH:ubiquinone oxidoreductase, subunit E; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol; Belongs to the NqrDE/RnfAE family.


ensembl_gene_id: Ssed_3428
symbol: nqrD
gene_biotype: protein_coding
description:
  NADH:ubiquinone oxidoreductase, subunit D; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol; Belongs to the NqrDE/RnfAE family.


ensembl_gene_id: Ssed_3429
symbol: nqrC
gene_biotype: protein_coding
description:
  NADH:ubiquinone oxidoreductase, subunit C; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.


ensembl_gene_id: Ssed_3430
symbol: nqrB
gene_biotype: protein_coding
description:
  NADH:ubiquinone oxidoreductase, subunit B; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.


ensembl_gene_id: Ssed_3431
symbol: nqrA
gene_biotype: protein_coding
description:
  NADH:ubiquinone oxidoreductase, subunit A; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.


ensembl_gene_id: Ssed_3432
symbol: luxS
gene_biotype: protein_coding
description:
  S-ribosylhomocysteine lyase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.


ensembl_gene_id: Ssed_3436
symbol: rlmG
gene_biotype: protein_coding
description:
  rRNA (guanine-N(2)-)-methyltransferase; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.


ensembl_gene_id: Ssed_3445
symbol: Ssed_3445
gene_biotype: protein_coding
description:
  2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.


ensembl_gene_id: Ssed_3446
symbol: Ssed_3446
gene_biotype: protein_coding
description:
  KEGG: ppr:PBPRA1510 putative sodium-dependent transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.


ensembl_gene_id: Ssed_3454
symbol: Ssed_3454
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_2908 transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_3458
symbol: prmC
gene_biotype: protein_coding
description:
  Modification methylase, HemK family; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.


ensembl_gene_id: Ssed_3459
symbol: prfA
gene_biotype: protein_coding
description:
  Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.


ensembl_gene_id: Ssed_3460
symbol: hemA
gene_biotype: protein_coding
description:
  Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).


ensembl_gene_id: Ssed_3461
symbol: lolB
gene_biotype: protein_coding
description:
  Outer membrane lipoprotein LolB; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.


ensembl_gene_id: Ssed_3462
symbol: ispE
gene_biotype: protein_coding
description:
  4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.


ensembl_gene_id: Ssed_3463
symbol: prs
gene_biotype: protein_coding
description:
  Ribose-phosphate diphosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.


ensembl_gene_id: Ssed_3465
symbol: Ssed_3465
gene_biotype: protein_coding
description:
  DNA-binding winged-HTH domains-like protein; KEGG: shw:Sputw3181_0585 transcriptional regulator, CadC.


ensembl_gene_id: Ssed_3467
symbol: ychF
gene_biotype: protein_coding
description:
  GTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.


ensembl_gene_id: Ssed_3468
symbol: pth
gene_biotype: protein_coding
description:
  Aminoacyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.


ensembl_gene_id: Ssed_3471
symbol: miaB
gene_biotype: protein_coding
description:
  2-alkenal reductase; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.


ensembl_gene_id: Ssed_3473
symbol: ybeY
gene_biotype: protein_coding
description:
  Protein of unknown function UPF0054; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.


ensembl_gene_id: Ssed_3475
symbol: lnt
gene_biotype: protein_coding
description:
  Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily.


ensembl_gene_id: Ssed_3479
symbol: leuS
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_2929 leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: Ssed_3480
symbol: lptE
gene_biotype: protein_coding
description:
  Rare lipoprotein B; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.


ensembl_gene_id: Ssed_3482
symbol: nadD
gene_biotype: protein_coding
description:
  Adenosine deaminase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).


ensembl_gene_id: Ssed_3483
symbol: rsfS
gene_biotype: protein_coding
description:
  Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.


ensembl_gene_id: Ssed_3484
symbol: rlmH
gene_biotype: protein_coding
description:
  Protein of unknown function DUF163; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family.


ensembl_gene_id: Ssed_3485
symbol: mrdA
gene_biotype: protein_coding
description:
  Peptidoglycan glycosyltransferase; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.


ensembl_gene_id: Ssed_3486
symbol: mrdB
gene_biotype: protein_coding
description:
  Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.


ensembl_gene_id: Ssed_3488
symbol: rlpA
gene_biotype: protein_coding
description:
  Rare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.


ensembl_gene_id: Ssed_3491
symbol: lipB
gene_biotype: protein_coding
description:
  Lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.


ensembl_gene_id: Ssed_3492
symbol: lipA
gene_biotype: protein_coding
description:
  Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.


ensembl_gene_id: Ssed_3493
symbol: Ssed_3493
gene_biotype: protein_coding
description:
  Ribosomal-protein-alanine acetyltransferase; Acetylates the N-terminal alanine of ribosomal protein S18.


ensembl_gene_id: Ssed_3495
symbol: Ssed_3495
gene_biotype: protein_coding
description:
  KEGG: saz:Sama_2600 CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: Ssed_3497
symbol: clpB
gene_biotype: protein_coding
description:
  ATPase AAA-2 domain protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.


ensembl_gene_id: Ssed_3498
symbol: Ssed_3498
gene_biotype: protein_coding
description:
  KEGG: sfr:Sfri_0668 protein of unknown function DUF152; Belongs to the multicopper oxidase YfiH/RL5 family.


ensembl_gene_id: Ssed_3500
symbol: bamD
gene_biotype: protein_coding
description:
  Putative lipoprotein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: Ssed_3504
symbol: Ssed_3504
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_2956 RNA polymerase, sigma-24 subunit, ECF subfamily; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: Ssed_3514
symbol: Ssed_3514
gene_biotype: protein_coding
description:
  Hypothetical protein; KEGG: neu:NE0566 domain of unknown function 2:response regulator receiver domain.


ensembl_gene_id: Ssed_3518
symbol: maeA
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_2962 malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)); Belongs to the malic enzymes family.


ensembl_gene_id: Ssed_3524
symbol: add
gene_biotype: protein_coding
description:
  KEGG: vvy:VVA1020 adenosine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.


ensembl_gene_id: Ssed_3526
symbol: queG
gene_biotype: protein_coding
description:
  Putative iron-sulfur cluster binding protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family.


ensembl_gene_id: Ssed_3528
symbol: Ssed_3528
gene_biotype: protein_coding
description:
  Hydrolase or acyltransferase (alpha/beta hydrolase superfamily)-like protein; KEGG: pnu:Pnuc_1320 alpha/beta hydrolase fold.


ensembl_gene_id: Ssed_3533
symbol: Ssed_3533
gene_biotype: protein_coding
description:
  KEGG: cps:CPS_2626 acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.


ensembl_gene_id: Ssed_3535
symbol: Ssed_3535
gene_biotype: protein_coding
description:
  KEGG: ppr:PBPRB1563 hypothetical transcription regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_3536
symbol: Ssed_3536
gene_biotype: protein_coding
description:
  Acetate/3-ketoacid CoA transferase; CoA transferase having broad substrate specificity for short- chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons. Belongs to the 3-oxoacid CoA-transferase family.


ensembl_gene_id: Ssed_3543
symbol: Ssed_3543
gene_biotype: protein_coding
description:
  Hypothetical protein; KEGG: slo:Shew_2983 Tat (twin-arginine translocation) pathway signal sequence domain protein.


ensembl_gene_id: Ssed_3552
symbol: Ssed_3552
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_2984 ferredoxin-dependent glutamate synthase; Belongs to the glutamate synthase family.


ensembl_gene_id: Ssed_3555
symbol: metE
gene_biotype: protein_coding
description:
  5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.


ensembl_gene_id: Ssed_3556
symbol: Ssed_3556
gene_biotype: protein_coding
description:
  KEGG: shn:Shewana3_3470 transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_3566
symbol: Ssed_3566
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_3153 transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_3573
symbol: Ssed_3573
gene_biotype: protein_coding
description:
  KEGG: pin:Ping_1040 chaperone endopeptidase Clp ATP-binding chain B,ClpB; Belongs to the ClpA/ClpB family.


ensembl_gene_id: Ssed_3576
symbol: Ssed_3576
gene_biotype: protein_coding
description:
  Carbonate dehydratase; KEGG: cps:CPS_1244 transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_3578
symbol: nqrE-2
gene_biotype: protein_coding
description:
  NADH:ubiquinone oxidoreductase, Na translocating, hydrophobic membrane protein NqrE; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol; Belongs to the NqrDE/RnfAE family.


ensembl_gene_id: Ssed_3583
symbol: Ssed_3583
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_3001 extracellular solute-binding protein, family 3; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: Ssed_3584
symbol: Ssed_3584
gene_biotype: protein_coding
description:
  KEGG: pin:Ping_1300 ABC sugar transporter inner membrane translocator; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: Ssed_3585
symbol: Ssed_3585
gene_biotype: protein_coding
description:
  KEGG: pin:Ping_1299 ABC transporter inner-membrane translocator; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: Ssed_3589
symbol: Ssed_3589
gene_biotype: protein_coding
description:
  Transcriptional regulator-like protein; KEGG: son:SO4571 transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_3590
symbol: Ssed_3590
gene_biotype: protein_coding
description:
  Transcriptional regulator-like protein; KEGG: shw:Sputw3181_3897 transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_3594
symbol: Ssed_3594
gene_biotype: protein_coding
description:
  KEGG: hch:HCH_04060 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain.


ensembl_gene_id: Ssed_3614
symbol: Ssed_3614
gene_biotype: protein_coding
description:
  KEGG: cps:CPS_2521 transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_3615
symbol: Ssed_3615
gene_biotype: protein_coding
description:
  KEGG: cps:CPS_3320 transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_3616
symbol: Ssed_3616
gene_biotype: protein_coding
description:
  KEGG: cps:CPS_3319 enoyl-CoA hydratase/isomerase family protein; Belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: Ssed_3636
symbol: Ssed_3636
gene_biotype: protein_coding
description:
  KEGG: nha:Nham_3287 molybdopterin oxidoreductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: Ssed_3645
symbol: Ssed_3645
gene_biotype: protein_coding
description:
  KEGG: cps:CPS_1338 putative glutamate-1-semialdehyde-2,1-aminomutase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: Ssed_3653
symbol: Ssed_3653
gene_biotype: protein_coding
description:
  Nitrite reductase (cytochrome; KEGG: shn:Shewana3_0658 cytochrome c552; Belongs to the cytochrome c-552 family.


ensembl_gene_id: Ssed_3663
symbol: Ssed_3663
gene_biotype: protein_coding
description:
  Multisubunit Na+/H+ antiporter MnhG subunit-like protein; KEGG: hne:HNE_0731 monovalent cation/proton antiporter, MnhG/PhaG family.


ensembl_gene_id: Ssed_3673
symbol: gcvP
gene_biotype: protein_coding
description:
  2-alkenal reductase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.


ensembl_gene_id: Ssed_3674
symbol: gcvH
gene_biotype: protein_coding
description:
  Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.


ensembl_gene_id: Ssed_3675
symbol: gcvT
gene_biotype: protein_coding
description:
  Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine.


ensembl_gene_id: Ssed_3679
symbol: Ssed_3679
gene_biotype: protein_coding
description:
  Protein of unknown function DUF710; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.


ensembl_gene_id: Ssed_3685
symbol: Ssed_3685
gene_biotype: protein_coding
description:
  CRP/FNR family transcriptional regulator, cyclic AMP receptor protein; KEGG: hch:HCH_03036 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase.


ensembl_gene_id: Ssed_3686
symbol: Ssed_3686
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_3069 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.


ensembl_gene_id: Ssed_3688
symbol: ung
gene_biotype: protein_coding
description:
  uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.


ensembl_gene_id: Ssed_3707
symbol: Ssed_3707
gene_biotype: protein_coding
description:
  KEGG: cps:CPS_3594 beta-ketoadipyl CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family.


ensembl_gene_id: Ssed_3708
symbol: Ssed_3708
gene_biotype: protein_coding
description:
  KEGG: cps:CPS_3593 putative glutamate-1-semialdehyde-2,1-aminomutase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: Ssed_3712
symbol: Ssed_3712
gene_biotype: protein_coding
description:
  KEGG: hch:HCH_06121 transcriptional regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_3731
symbol: cobQ-2
gene_biotype: protein_coding
description:
  Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.


ensembl_gene_id: Ssed_3734
symbol: cobT
gene_biotype: protein_coding
description:
  Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).


ensembl_gene_id: Ssed_3735
symbol: Ssed_3735
gene_biotype: protein_coding
description:
  KEGG: sbl:Sbal_3365 transport system permease protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: Ssed_3738
symbol: Ssed_3738
gene_biotype: protein_coding
description:
  Na+/proline symporter-like protein; KEGG: sfu:Sfum_0294 multi-sensor signal transduction histidine kinase.


ensembl_gene_id: Ssed_3739
symbol: Ssed_3739
gene_biotype: protein_coding
description:
  Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.


ensembl_gene_id: Ssed_3742
symbol: Ssed_3742
gene_biotype: protein_coding
description:
  KEGG: ppr:PBPRB1418 hypothetical transcriptional regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_3744
symbol: Ssed_3744
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_0844 nitrite reductase (cytochrome; ammonia-forming); Belongs to the cytochrome c-552 family.


ensembl_gene_id: Ssed_3760
symbol: Ssed_3760
gene_biotype: protein_coding
description:
  KEGG: shw:Sputw3181_0918 extracellular solute-binding protein, family 3; Belongs to the bacterial solute-binding protein 3 family.


ensembl_gene_id: Ssed_3772
symbol: selO
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation). Belongs to the SELO family.


ensembl_gene_id: Ssed_3778
symbol: Ssed_3778
gene_biotype: protein_coding
description:
  Response regulator containing a CheY-like protein receiver domain and an HD-GYP domain-like protein; KEGG: reu:Reut_B4068 response regulator receiver:metal-dependent phosphohydrolase, HD subdomain.


ensembl_gene_id: Ssed_3797
symbol: Ssed_3797
gene_biotype: protein_coding
description:
  KEGG: sbl:Sbal_3409 uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family.


ensembl_gene_id: Ssed_3805
symbol: cysH
gene_biotype: protein_coding
description:
  Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.


ensembl_gene_id: Ssed_3806
symbol: cysI
gene_biotype: protein_coding
description:
  Sulfite reductase (NADPH) hemoprotein, beta-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.


ensembl_gene_id: Ssed_3807
symbol: Ssed_3807
gene_biotype: protein_coding
description:
  Sulfite reductase (NADPH) flavoprotein, alpha chain; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.


ensembl_gene_id: Ssed_3812
symbol: hldE
gene_biotype: protein_coding
description:
  RfaE bifunctional protein; Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7- phosphate at the C-1 position to selectively form D-glycero-beta-D- manno-heptose-1,7-bisphosphate; In the C-terminal section; belongs to the cytidylyltransferase family.


ensembl_gene_id: Ssed_3813
symbol: lpxL
gene_biotype: protein_coding
description:
  Lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase; Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A).


ensembl_gene_id: Ssed_3821
symbol: nhaP2
gene_biotype: protein_coding
description:
  Sodium/hydrogen exchanger; K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. NhaP2 subfamily.


ensembl_gene_id: Ssed_3833
symbol: glnE
gene_biotype: protein_coding
description:
  (Glutamate--ammonia-ligase) adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal tra [...]


ensembl_gene_id: Ssed_3836
symbol: speE
gene_biotype: protein_coding
description:
  Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.


ensembl_gene_id: Ssed_3846
symbol: Ssed_3846
gene_biotype: protein_coding
description:
  Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: Ssed_3851
symbol: rhlE
gene_biotype: protein_coding
description:
  DEAD/DEAH box helicase domain protein; DEAD-box RNA helicase involved in ribosome assembly. Has RNA- dependent ATPase activity and unwinds double-stranded RNA.


ensembl_gene_id: Ssed_3852
symbol: Ssed_3852
gene_biotype: protein_coding
description:
  KEGG: shm:Shewmr7_3275 DEAD/DEAH box helicase domain protein; Belongs to the DEAD box helicase family.


ensembl_gene_id: Ssed_3868
symbol: Ssed_3868
gene_biotype: protein_coding
description:
  KEGG: pha:PSHAa0579 cobalt-zinc-cadmium resistance protein CzcA (cation efflux system protein CzcA); Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: Ssed_3877
symbol: Ssed_3877
gene_biotype: protein_coding
description:
  Succinate dehydrogenase; KEGG: slo:Shew_3112 flavocytochrome c; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.


ensembl_gene_id: Ssed_3880
symbol: Ssed_3880
gene_biotype: protein_coding
description:
  Signal transduction histidine kinase regulating C4-dicarboxylate transport system-like protein; KEGG: vvu:VV2_0464 signal transduction histidine kinase.


ensembl_gene_id: Ssed_3882
symbol: Ssed_3882
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_3115 sodium:dicarboxylate symporter; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: Ssed_3894
symbol: Ssed_3894
gene_biotype: protein_coding
description:
  Peptidoglycan glycosyltransferase; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).


ensembl_gene_id: Ssed_3896
symbol: Ssed_3896
gene_biotype: protein_coding
description:
  2'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family.


ensembl_gene_id: Ssed_3899
symbol: dksA
gene_biotype: protein_coding
description:
  Transcriptional regulator, TraR/DksA family; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.


ensembl_gene_id: Ssed_3900
symbol: gluQ
gene_biotype: protein_coding
description:
  glutamyl-tRNA synthetase, class Ic; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.


ensembl_gene_id: Ssed_3901
symbol: pcnB
gene_biotype: protein_coding
description:
  Polynucleotide adenylyltransferase; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control. Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.


ensembl_gene_id: Ssed_3903
symbol: panB
gene_biotype: protein_coding
description:
  3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.


ensembl_gene_id: Ssed_3904
symbol: panC
gene_biotype: protein_coding
description:
  Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.


ensembl_gene_id: Ssed_3910
symbol: Ssed_3910
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_3142 hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.


ensembl_gene_id: Ssed_3911
symbol: ubiX
gene_biotype: protein_coding
description:
  3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family.


ensembl_gene_id: Ssed_3912
symbol: mpl
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramate; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily.


ensembl_gene_id: Ssed_3916
symbol: tnaA
gene_biotype: protein_coding
description:
  Tryptophanase; KEGG: ppr:PBPRB0382 putative tryptophanase; Belongs to the beta-eliminating lyase family.


ensembl_gene_id: Ssed_3921
symbol: Ssed_3921
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_3007 transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_3926
symbol: lgt
gene_biotype: protein_coding
description:
  Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.


ensembl_gene_id: Ssed_3928
symbol: Ssed_3928
gene_biotype: protein_coding
description:
  (S)-3-amino-2-methylpropionate transaminase; KEGG: slo:Shew_3172 4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: Ssed_3929
symbol: Ssed_3929
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_3173 succinic semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: Ssed_3930
symbol: Ssed_3930
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_3174 transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_3932
symbol: Ssed_3932
gene_biotype: protein_coding
description:
  KEGG: hch:HCH_05487 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain.


ensembl_gene_id: Ssed_3937
symbol: Ssed_3937
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.


ensembl_gene_id: Ssed_3948
symbol: Ssed_3948
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_3198 glycine cleavage T protein (aminomethyl transferase); Belongs to the GcvT family.


ensembl_gene_id: Ssed_3951
symbol: Ssed_3951
gene_biotype: protein_coding
description:
  Thiol-disulfide isomerase and thioredoxins-like protein; KEGG: gur:Gura_3739 alkyl hydroperoxide reductase/thiol specific antioxidant/Mal allergen.


ensembl_gene_id: Ssed_3956
symbol: napD-2
gene_biotype: protein_coding
description:
  NapD family protein; Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin- arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.


ensembl_gene_id: Ssed_3957
symbol: napA-2
gene_biotype: protein_coding
description:
  Periplasmic nitrate reductase, large subunit; Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.


ensembl_gene_id: Ssed_3968
symbol: Ssed_3968
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_3219 transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_3972
symbol: Ssed_3972
gene_biotype: protein_coding
description:
  Protein of unknown function DUF558; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.


ensembl_gene_id: Ssed_3978
symbol: rsmC
gene_biotype: protein_coding
description:
  rRNA (guanine-N(2)-)-methyltransferase; Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle; Belongs to the methyltransferase superfamily. RsmC family.


ensembl_gene_id: Ssed_3981
symbol: Ssed_3981
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_3242 transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_3982
symbol: Ssed_3982
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_3243 molydopterin dinucleotide-binding region; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: Ssed_3988
symbol: Ssed_3988
gene_biotype: protein_coding
description:
  KEGG: vfi:VFA0214 probable transcriptional regulator SyrB; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_3992
symbol: Ssed_3992
gene_biotype: protein_coding
description:
  KEGG: ilo:IL0466 RND efflux system membrane fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: Ssed_3993
symbol: Ssed_3993
gene_biotype: protein_coding
description:
  KEGG: pha:PSHAb0438 putative metabolite exporter, AcrB/D/F family; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: Ssed_4006
symbol: pepT
gene_biotype: protein_coding
description:
  Tripeptide aminopeptidase; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family.


ensembl_gene_id: Ssed_4010
symbol: tpm
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_3261 thiopurine S-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.


ensembl_gene_id: Ssed_4015
symbol: dsbD
gene_biotype: protein_coding
description:
  Protein-disulfide reductase; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily.


ensembl_gene_id: Ssed_4016
symbol: Ssed_4016
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_3267 sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.


ensembl_gene_id: Ssed_4019
symbol: Ssed_4019
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_3270 SSS sodium solute transporter superfamily; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: Ssed_4020
symbol: galK
gene_biotype: protein_coding
description:
  Galactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily.


ensembl_gene_id: Ssed_4025
symbol: Ssed_4025
gene_biotype: protein_coding
description:
  Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.


ensembl_gene_id: Ssed_4027
symbol: uvrA
gene_biotype: protein_coding
description:
  Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.


ensembl_gene_id: Ssed_4029
symbol: deaD
gene_biotype: protein_coding
description:
  DEAD/DEAH box helicase domain protein; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.


ensembl_gene_id: Ssed_4039
symbol: Ssed_4039
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_0522 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.


ensembl_gene_id: Ssed_4040
symbol: Ssed_4040
gene_biotype: protein_coding
description:
  Aspartate kinase., Homoserine dehydrogenase; KEGG: slo:Shew_0521 aspartate kinase; In the C-terminal section; belongs to the homoserine dehydrogenase family.


ensembl_gene_id: Ssed_4042
symbol: Ssed_4042
gene_biotype: protein_coding
description:
  Met repressor; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis.


ensembl_gene_id: Ssed_4047
symbol: Ssed_4047
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_0608 molybdopterin oxidoreductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: Ssed_4050
symbol: Ssed_4050
gene_biotype: protein_coding
description:
  Methylase involved in ubiquinone/menaquinone biosynthesis-like protein; KEGG: stp:Strop_2596 methyltransferase type 11.


ensembl_gene_id: Ssed_4052
symbol: Ssed_4052
gene_biotype: protein_coding
description:
  KEGG: sfr:Sfri_1582 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Belongs to the FAD-dependent oxidoreductase family.


ensembl_gene_id: Ssed_4056
symbol: Ssed_4056
gene_biotype: protein_coding
description:
  KEGG: cps:CPS_4936 substrate-binding transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_4057
symbol: Ssed_4057
gene_biotype: protein_coding
description:
  KEGG: shn:Shewana3_3687 short-chain dehydrogenase/reductase SDR; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: Ssed_4064
symbol: Ssed_4064
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_0506 transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_4081
symbol: Ssed_4081
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_3356 heavy metal efflux pump, CzcA family; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: Ssed_4082
symbol: Ssed_4082
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_3357 efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: Ssed_4088
symbol: aroQ
gene_biotype: protein_coding
description:
  3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.


ensembl_gene_id: Ssed_4089
symbol: Ssed_4089
gene_biotype: protein_coding
description:
  acetylCoA carboxylase, BccP subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.


ensembl_gene_id: Ssed_4090
symbol: Ssed_4090
gene_biotype: protein_coding
description:
  Acetyl CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.


ensembl_gene_id: Ssed_4094
symbol: rraA
gene_biotype: protein_coding
description:
  Protein of unknown function 1935; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome.


ensembl_gene_id: Ssed_4096
symbol: ubiE
gene_biotype: protein_coding
description:
  Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2).


ensembl_gene_id: Ssed_4098
symbol: ubiB
gene_biotype: protein_coding
description:
  2-polyprenylphenol 6-hydroxylase; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.


ensembl_gene_id: Ssed_4099
symbol: tatA
gene_biotype: protein_coding
description:
  Twin-arginine translocation protein, TatA/E family subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.


ensembl_gene_id: Ssed_4100
symbol: tatB
gene_biotype: protein_coding
description:
  Twin-arginine translocation protein, TatB subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.


ensembl_gene_id: Ssed_4101
symbol: tatC
gene_biotype: protein_coding
description:
  Sec-independent protein translocase, TatC subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.


ensembl_gene_id: Ssed_4109
symbol: rhlB
gene_biotype: protein_coding
description:
  DEAD/DEAH box helicase domain protein; DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. Belongs to the DEAD box helicase family. RhlB subfamily.


ensembl_gene_id: Ssed_4111
symbol: rho
gene_biotype: protein_coding
description:
  Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.


ensembl_gene_id: Ssed_4112
symbol: Ssed_4112
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_0336 transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_4113
symbol: Ssed_4113
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_0335 succinate dehydrogenase and fumarate reductase iron-sulfur protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.


ensembl_gene_id: Ssed_4117
symbol: prmA
gene_biotype: protein_coding
description:
  Ribosomal protein L11 methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family.


ensembl_gene_id: Ssed_4118
symbol: dusB
gene_biotype: protein_coding
description:
  Putative TIM-barrel protein, nifR3 family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily.


ensembl_gene_id: Ssed_4119
symbol: fis
gene_biotype: protein_coding
description:
  Transcriptional regulator, fis family; Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters; Belongs to the transcriptional regulatory Fis family.


ensembl_gene_id: Ssed_4124
symbol: Ssed_4124
gene_biotype: protein_coding
description:
  Protein of unknown function DUF542, ScdA domain protein; Di-iron-containing protein involved in the repair of iron- sulfur clusters; Belongs to the RIC family.


ensembl_gene_id: Ssed_4127
symbol: xerC
gene_biotype: protein_coding
description:
  Tyrosine recombinase XerC; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.


ensembl_gene_id: Ssed_4129
symbol: dapF
gene_biotype: protein_coding
description:
  Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.


ensembl_gene_id: Ssed_4130
symbol: lysA
gene_biotype: protein_coding
description:
  Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.


ensembl_gene_id: Ssed_4131
symbol: cyaY
gene_biotype: protein_coding
description:
  Frataxin family protein; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.


ensembl_gene_id: Ssed_4132
symbol: Ssed_4132
gene_biotype: protein_coding
description:
  Adenylate cyclase; KEGG: slo:Shew_0319 putative adenylate cyclase; Belongs to the adenylyl cyclase class-1 family.


ensembl_gene_id: Ssed_4133
symbol: hemC
gene_biotype: protein_coding
description:
  Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.


ensembl_gene_id: Ssed_4134
symbol: Ssed_4134
gene_biotype: protein_coding
description:
  Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.


ensembl_gene_id: Ssed_4147
symbol: rep
gene_biotype: protein_coding
description:
  ATP-dependent DNA helicase Rep; Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.


ensembl_gene_id: Ssed_4149
symbol: Ssed_4149
gene_biotype: protein_coding
description:
  KEGG: shn:Shewana3_0372 efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: Ssed_4150
symbol: Ssed_4150
gene_biotype: protein_coding
description:
  KEGG: shn:Shewana3_0371 acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: Ssed_4161
symbol: ilvA
gene_biotype: protein_coding
description:
  Threonine dehydratase, biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.


ensembl_gene_id: Ssed_4163
symbol: ilvE
gene_biotype: protein_coding
description:
  Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: Ssed_4166
symbol: Ssed_4166
gene_biotype: protein_coding
description:
  Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.


ensembl_gene_id: Ssed_4167
symbol: Ssed_4167
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_0287 transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_4176
symbol: Ssed_4176
gene_biotype: protein_coding
description:
  Branched-chain-amino-acid transaminase; KEGG: slo:Shew_0278 branched-chain amino acid aminotransferase.


ensembl_gene_id: Ssed_4178
symbol: Ssed_4178
gene_biotype: protein_coding
description:
  KEGG: son:SO3624 flavocytochrome c flavin subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.


ensembl_gene_id: Ssed_4184
symbol: Ssed_4184
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_0276 flavocytochrome c; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.


ensembl_gene_id: Ssed_4191
symbol: zapB
gene_biotype: protein_coding
description:
  Protein of unknown function DUF904; Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA.


ensembl_gene_id: Ssed_4194
symbol: srkA
gene_biotype: protein_coding
description:
  Aminoglycoside phosphotransferase; A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.


ensembl_gene_id: Ssed_4208
symbol: Ssed_4208
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_0245 molydopterin dinucleotide-binding region; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: Ssed_4210
symbol: Ssed_4210
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_0243 transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_4211
symbol: Ssed_4211
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_0242 molydopterin dinucleotide-binding region; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: Ssed_4223
symbol: Ssed_4223
gene_biotype: protein_coding
description:
  KEGG: ilo:IL1531 short chain dehydrogenase/reductase family protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: Ssed_4227
symbol: Ssed_4227
gene_biotype: protein_coding
description:
  KEGG: sfr:Sfri_3427 alcohol dehydrogenase GroES domain protein; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.


ensembl_gene_id: Ssed_4230
symbol: gfa
gene_biotype: protein_coding
description:
  S-(hydroxymethyl)glutathione synthase; Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione; Belongs to the Gfa family.


ensembl_gene_id: Ssed_4232
symbol: Ssed_4232
gene_biotype: protein_coding
description:
  Carbonate dehydratase; KEGG: sfr:Sfri_3440 transcriptional regulator, LysR family protein; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_4250
symbol: rsmI
gene_biotype: protein_coding
description:
  uroporphyrin-III C/tetrapyrrole (corrin/porphyrin) methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.


ensembl_gene_id: Ssed_4253
symbol: gmhA
gene_biotype: protein_coding
description:
  Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.


ensembl_gene_id: Ssed_4256
symbol: Ssed_4256
gene_biotype: protein_coding
description:
  KEGG: sbl:Sbal_4104 transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Ssed_4257
symbol: trpS
gene_biotype: protein_coding
description:
  Tryptophan--tRNA ligase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: Ssed_4258
symbol: gph
gene_biotype: protein_coding
description:
  Phosphoglycolate phosphatase; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.


ensembl_gene_id: Ssed_4259
symbol: Ssed_4259
gene_biotype: protein_coding
description:
  KEGG: son:SO0292 ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.


ensembl_gene_id: Ssed_4264
symbol: aroB
gene_biotype: protein_coding
description:
  3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.


ensembl_gene_id: Ssed_4265
symbol: aroK
gene_biotype: protein_coding
description:
  Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.


ensembl_gene_id: Ssed_4273
symbol: argG
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_0205 argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.


ensembl_gene_id: Ssed_4274
symbol: Ssed_4274
gene_biotype: protein_coding
description:
  Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.


ensembl_gene_id: Ssed_4275
symbol: argB
gene_biotype: protein_coding
description:
  Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.


ensembl_gene_id: Ssed_4276
symbol: argC
gene_biotype: protein_coding
description:
  N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.


ensembl_gene_id: Ssed_4278
symbol: ppc
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.


ensembl_gene_id: Ssed_4287
symbol: ccmA
gene_biotype: protein_coding
description:
  Heme exporter protein CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.


ensembl_gene_id: Ssed_4288
symbol: Ssed_4288
gene_biotype: protein_coding
description:
  Heme exporter protein CcmB; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family.


ensembl_gene_id: Ssed_4289
symbol: ccmC
gene_biotype: protein_coding
description:
  Heme exporter protein CcmC; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family.


ensembl_gene_id: Ssed_4290
symbol: Ssed_4290
gene_biotype: protein_coding
description:
  Heme exporter protein D (CcmD); Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmD/CycX/HelD family.


ensembl_gene_id: Ssed_4291
symbol: ccmE
gene_biotype: protein_coding
description:
  CcmE/CycJ protein; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family.


ensembl_gene_id: Ssed_4294
symbol: rpoA
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: Ssed_4295
symbol: rpsD
gene_biotype: protein_coding
description:
  Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.


ensembl_gene_id: Ssed_4296
symbol: rpsK
gene_biotype: protein_coding
description:
  Ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.


ensembl_gene_id: Ssed_4297
symbol: rpsM
gene_biotype: protein_coding
description:
  Ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family.


ensembl_gene_id: Ssed_4298
symbol: secY
gene_biotype: protein_coding
description:
  Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.


ensembl_gene_id: Ssed_4299
symbol: rplO
gene_biotype: protein_coding
description:
  Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.


ensembl_gene_id: Ssed_4300
symbol: rpsE
gene_biotype: protein_coding
description:
  Ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.


ensembl_gene_id: Ssed_4301
symbol: rplR
gene_biotype: protein_coding
description:
  Ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.


ensembl_gene_id: Ssed_4302
symbol: rplF
gene_biotype: protein_coding
description:
  Ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.


ensembl_gene_id: Ssed_4303
symbol: rpsH
gene_biotype: protein_coding
description:
  Ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.


ensembl_gene_id: Ssed_4304
symbol: rpsN
gene_biotype: protein_coding
description:
  Ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family.


ensembl_gene_id: Ssed_4305
symbol: rplE
gene_biotype: protein_coding
description:
  Ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.


ensembl_gene_id: Ssed_4306
symbol: rplX
gene_biotype: protein_coding
description:
  Ribosomal protein L24; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.


ensembl_gene_id: Ssed_4307
symbol: rplN
gene_biotype: protein_coding
description:
  Ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.


ensembl_gene_id: Ssed_4308
symbol: rpsQ
gene_biotype: protein_coding
description:
  Ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.


ensembl_gene_id: Ssed_4310
symbol: rplP
gene_biotype: protein_coding
description:
  Ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.


ensembl_gene_id: Ssed_4311
symbol: rpsC
gene_biotype: protein_coding
description:
  Ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.


ensembl_gene_id: Ssed_4312
symbol: rplV
gene_biotype: protein_coding
description:
  Ribosomal protein L22; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).


ensembl_gene_id: Ssed_4313
symbol: rpsS
gene_biotype: protein_coding
description:
  Ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.


ensembl_gene_id: Ssed_4314
symbol: rplB
gene_biotype: protein_coding
description:
  Ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.


ensembl_gene_id: Ssed_4315
symbol: rplW
gene_biotype: protein_coding
description:
  Ribosomal protein L25/L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.


ensembl_gene_id: Ssed_4316
symbol: rplD
gene_biotype: protein_coding
description:
  Ribosomal protein L4/L1e; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.


ensembl_gene_id: Ssed_4317
symbol: rplC
gene_biotype: protein_coding
description:
  Ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.


ensembl_gene_id: Ssed_4318
symbol: rpsJ
gene_biotype: protein_coding
description:
  Ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.


ensembl_gene_id: Ssed_4319
symbol: tuf
gene_biotype: protein_coding
description:
  Translation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.


ensembl_gene_id: Ssed_4321
symbol: rpsG
gene_biotype: protein_coding
description:
  30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.


ensembl_gene_id: Ssed_4323
symbol: rpoC
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: Ssed_4324
symbol: rpoB
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: Ssed_4325
symbol: rplL
gene_biotype: protein_coding
description:
  Ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family.


ensembl_gene_id: Ssed_4326
symbol: rplJ
gene_biotype: protein_coding
description:
  Ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.


ensembl_gene_id: Ssed_4327
symbol: rplA
gene_biotype: protein_coding
description:
  Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.


ensembl_gene_id: Ssed_4328
symbol: rplK
gene_biotype: protein_coding
description:
  Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.


ensembl_gene_id: Ssed_4329
symbol: nusG
gene_biotype: protein_coding
description:
  NusG antitermination factor; Participates in transcription elongation, termination and antitermination.


ensembl_gene_id: Ssed_4330
symbol: secE
gene_biotype: protein_coding
description:
  Preprotein translocase, SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61-gamma family.


ensembl_gene_id: Ssed_4334
symbol: birA
gene_biotype: protein_coding
description:
  Biotin--(acetyl-CoA-carboxylase) ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.


ensembl_gene_id: Ssed_4338
symbol: trmA
gene_biotype: protein_coding
description:
  tRNA (uracil-5-)-methyltransferase; Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).


ensembl_gene_id: Ssed_4342
symbol: selU
gene_biotype: protein_coding
description:
  Rhodanese domain protein; Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2- selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.


ensembl_gene_id: Ssed_4345
symbol: cysQ
gene_biotype: protein_coding
description:
  3'(2'),5'-bisphosphate nucleotidase; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family.


ensembl_gene_id: Ssed_4349
symbol: Ssed_4349
gene_biotype: protein_coding
description:
  General secretion pathway M protein; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.


ensembl_gene_id: Ssed_4350
symbol: Ssed_4350
gene_biotype: protein_coding
description:
  General secretion pathway protein L; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.


ensembl_gene_id: Ssed_4357
symbol: Ssed_4357
gene_biotype: protein_coding
description:
  General secretory pathway protein E; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.


ensembl_gene_id: Ssed_4361
symbol: hslO
gene_biotype: protein_coding
description:
  HSP33 protein; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.


ensembl_gene_id: Ssed_4362
symbol: pckA
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.


ensembl_gene_id: Ssed_4372
symbol: ribB-2
gene_biotype: protein_coding
description:
  3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.


ensembl_gene_id: Ssed_4375
symbol: Ssed_4375
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_0044 acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: Ssed_4376
symbol: Ssed_4376
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_0045 efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: Ssed_4377
symbol: Ssed_4377
gene_biotype: protein_coding
description:
  Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.


ensembl_gene_id: Ssed_4386
symbol: gltS-2
gene_biotype: protein_coding
description:
  Sodium/glutamate symporter; Catalyzes the sodium-dependent transport of glutamate. Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.


ensembl_gene_id: Ssed_4396
symbol: Ssed_4396
gene_biotype: protein_coding
description:
  Molybdate ABC transporter, inner membrane subunit; Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: Ssed_4400
symbol: moaC
gene_biotype: protein_coding
description:
  Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.


ensembl_gene_id: Ssed_4401
symbol: Ssed_4401
gene_biotype: protein_coding
description:
  Molybdenum cofactor biosynthesis protein B; May be involved in the biosynthesis of molybdopterin. Belongs to the MoaB/Mog family.


ensembl_gene_id: Ssed_4403
symbol: Ssed_4403
gene_biotype: protein_coding
description:
  Electron-transferring-flavoprotein dehydrogenase; Accepts electrons from ETF and reduces ubiquinone.


ensembl_gene_id: Ssed_4417
symbol: Ssed_4417
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_0063 molybdopterin oxidoreductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: Ssed_4421
symbol: Ssed_4421
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_0059 molybdopterin oxidoreductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: Ssed_4427
symbol: fdhD
gene_biotype: protein_coding
description:
  Formate dehydrogenase, subunit FdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.


ensembl_gene_id: Ssed_4429
symbol: rlmF
gene_biotype: protein_coding
description:
  Protein of unknown function DUF890; Specifically methylates the adenine in position 1618 of 23S rRNA.


ensembl_gene_id: Ssed_4431
symbol: ubiC
gene_biotype: protein_coding
description:
  Chorismate lyase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family.


ensembl_gene_id: Ssed_4449
symbol: hutI
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_3759 imidazolonepropionase; Belongs to the metallo-dependent hydrolases superfamily. HutI family.


ensembl_gene_id: Ssed_4454
symbol: mtnC
gene_biotype: protein_coding
description:
  2,3-diketo-5-methylthio-1-phosphopentane phosphatase; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.


ensembl_gene_id: Ssed_4467
symbol: gpsA
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_3803 glycerol-3-phosphate dehydrogenase (NAD(P)(+)); Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.


ensembl_gene_id: Ssed_4468
symbol: secB
gene_biotype: protein_coding
description:
  Protein-export protein SecB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.


ensembl_gene_id: Ssed_4470
symbol: gpmI
gene_biotype: protein_coding
description:
  Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.


ensembl_gene_id: Ssed_4472
symbol: Ssed_4472
gene_biotype: protein_coding
description:
  C-terminal processing peptidase; KEGG: slo:Shew_3808 carboxyl-terminal protease; Belongs to the peptidase S41A family.


ensembl_gene_id: Ssed_4478
symbol: menB
gene_biotype: protein_coding
description:
  Naphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA); Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.


ensembl_gene_id: Ssed_4481
symbol: glmS
gene_biotype: protein_coding
description:
  Glucosamine--fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.


ensembl_gene_id: Ssed_4484
symbol: glmU
gene_biotype: protein_coding
description:
  UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family.


ensembl_gene_id: Ssed_4485
symbol: atpC
gene_biotype: protein_coding
description:
  ATP synthase F1, epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane.


ensembl_gene_id: Ssed_4486
symbol: atpD
gene_biotype: protein_coding
description:
  ATP synthase F1, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family.


ensembl_gene_id: Ssed_4487
symbol: atpG
gene_biotype: protein_coding
description:
  H(+)-transporting two-sector ATPase; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.


ensembl_gene_id: Ssed_4488
symbol: atpA
gene_biotype: protein_coding
description:
  H(+)-transporting two-sector ATPase; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family.


ensembl_gene_id: Ssed_4489
symbol: atpH
gene_biotype: protein_coding
description:
  H(+)-transporting two-sector ATPase; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family.


ensembl_gene_id: Ssed_4490
symbol: atpF
gene_biotype: protein_coding
description:
  ATP synthase F0, B subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.


ensembl_gene_id: Ssed_4491
symbol: atpE
gene_biotype: protein_coding
description:
  ATP synthase F0, C subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.


ensembl_gene_id: Ssed_4492
symbol: atpB
gene_biotype: protein_coding
description:
  ATP synthase F0, A subunit; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.


ensembl_gene_id: Ssed_4496
symbol: rsmG
gene_biotype: protein_coding
description:
  Methyltransferase GidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.


ensembl_gene_id: Ssed_4497
symbol: mnmG
gene_biotype: protein_coding
description:
  Glucose inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family.


