# geneInfo

ensembl_gene_id: PYK22_00002
symbol: rpmG
gene_biotype: protein_coding
description:
  PFAM: Ribosomal protein L33; TIGRFAM: ribosomal protein L33, bacterial type; Belongs to the bacterial ribosomal protein bL33 family.


ensembl_gene_id: PYK22_00004
symbol: secE
gene_biotype: protein_coding
description:
  Preprotein translocase, SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.


ensembl_gene_id: PYK22_00005
symbol: nusG
gene_biotype: protein_coding
description:
  Transcription antitermination protein nusG; Participates in transcription elongation, termination and antitermination.


ensembl_gene_id: PYK22_00006
symbol: rplK
gene_biotype: protein_coding
description:
  LSU ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.


ensembl_gene_id: PYK22_00007
symbol: rplA
gene_biotype: protein_coding
description:
  LSU ribosomal protein L1P; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.


ensembl_gene_id: PYK22_00008
symbol: rplJ
gene_biotype: protein_coding
description:
  LSU ribosomal protein L10P; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.


ensembl_gene_id: PYK22_00009
symbol: rplL
gene_biotype: protein_coding
description:
  LSU ribosomal protein L12P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family.


ensembl_gene_id: PYK22_00010
symbol: rpoB
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: PYK22_00012
symbol: CDM64020.1
gene_biotype: protein_coding
description:
  uroporphyrinogen-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family.


ensembl_gene_id: PYK22_00015
symbol: CDM64023.1
gene_biotype: protein_coding
description:
  Assimilatory nitrite reductase (NAD(P)H) large subunit precursor; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Nitrite and sulphite reductase 4Fe-4S domain; BFD-like [2Fe-2S] binding domain; Nitrite/Sulfite reductase ferredoxin-like half domain; TIGRFAM: nitrite reductase [NAD(P)H], large subunit.


ensembl_gene_id: PYK22_00016
symbol: CDM64024.1
gene_biotype: protein_coding
description:
  NAD(P)H-nitrite reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; BFD-like [2Fe-2S] binding domain; TIGRFAM: nitrite reductase [NAD(P)H], large subunit.


ensembl_gene_id: PYK22_00017
symbol: CDM64025.1
gene_biotype: protein_coding
description:
  Assimilatory nitrate reductase (NADH) alpha subunit apoprotein; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; Molybdopterin oxidoreductase Fe4S4 domain; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: PYK22_00018
symbol: CDM64026.1
gene_biotype: protein_coding
description:
  Nitrate/nitrite transporter; PFAM: Major Facilitator Superfamily; TIGRFAM: nitrite extrusion protein (nitrite facilitator).


ensembl_gene_id: PYK22_00019
symbol: CDM64027.1
gene_biotype: protein_coding
description:
  PFAM: GAF domain; Bacterial regulatory protein, Fis family; Sigma-54 interaction domain; TIGRFAM: Nif-specific regulatory protein.


ensembl_gene_id: PYK22_00022
symbol: CDM64030.1
gene_biotype: protein_coding
description:
  PFAM: TonB dependent receptor; TonB-dependent Receptor Plug Domain; Carboxypeptidase regulatory-like domain; TIGRFAM: TonB-dependent siderophore receptor.


ensembl_gene_id: PYK22_00031
symbol: CDM64039.1
gene_biotype: protein_coding
description:
  Endopolygalacturonase; PFAM: Glycosyl hydrolases family 28; Belongs to the glycosyl hydrolase 28 family.


ensembl_gene_id: PYK22_00035
symbol: CDM64043.1
gene_biotype: protein_coding
description:
  PFAM: Pyruvate kinase, barrel domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family.


ensembl_gene_id: PYK22_00040
symbol: CDM64048.1
gene_biotype: protein_coding
description:
  PFAM: GGDEF domain; Response regulator receiver domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.


ensembl_gene_id: PYK22_00058
symbol: CDM64066.1
gene_biotype: protein_coding
description:
  PFAM: Peptidase S24-like; TIGRFAM: signal peptidase I, bacterial type; Belongs to the peptidase S26 family.


ensembl_gene_id: PYK22_00060
symbol: carA
gene_biotype: protein_coding
description:
  PFAM: Carbamoyl-phosphate synthase small chain, CPSase domain; Glutamine amidotransferase class-I; TIGRFAM: carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family.


ensembl_gene_id: PYK22_00064
symbol: CDM64072.1
gene_biotype: protein_coding
description:
  Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains; PFAM: Response regulator receiver domain.


ensembl_gene_id: PYK22_00066
symbol: CDM64074.1
gene_biotype: protein_coding
description:
  Integral membrane protein CcmA involved in cell shape determination; PFAM: Polymer-forming cytoskeletal.


ensembl_gene_id: PYK22_00067
symbol: leuD
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.


ensembl_gene_id: PYK22_00068
symbol: leuC
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.


ensembl_gene_id: PYK22_00069
symbol: leuB
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.


ensembl_gene_id: PYK22_00070
symbol: CDM64078.1
gene_biotype: protein_coding
description:
  Isopropylmalate/homocitrate/citramalate synthase; PFAM: HMGL-like; Belongs to the alpha-IPM synthase/homocitrate synthase family.


ensembl_gene_id: PYK22_00071
symbol: CDM64079.1
gene_biotype: protein_coding
description:
  Transcriptional regulator; PFAM: LysR substrate binding domain; Bacterial regulatory helix-turn-helix protein, lysR family; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: PYK22_00073
symbol: CDM64081.1
gene_biotype: protein_coding
description:
  Acetolactate synthase, large subunit; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: acetolactate synthase, large subunit, biosynthetic type.


ensembl_gene_id: PYK22_00074
symbol: CDM64082.1
gene_biotype: protein_coding
description:
  PFAM: Small subunit of acetolactate synthase; ACT domain; TIGRFAM: acetolactate synthase, small subunit.


ensembl_gene_id: PYK22_00075
symbol: ilvC
gene_biotype: protein_coding
description:
  Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.


ensembl_gene_id: PYK22_00077
symbol: CDM64085.1
gene_biotype: protein_coding
description:
  Cystathionine beta-lyase/cystathionine gamma-synthase; PFAM: Cys/Met metabolism PLP-dependent enzyme.


ensembl_gene_id: PYK22_00078
symbol: CDM64086.1
gene_biotype: protein_coding
description:
  Aspartate kinase; PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; Amino acid kinase family; TIGRFAM: aspartate kinase.


ensembl_gene_id: PYK22_00079
symbol: CDM64087.1
gene_biotype: protein_coding
description:
  Cystathionine beta-lyase, eukaryotic; PFAM: Cys/Met metabolism PLP-dependent enzyme; TIGRFAM: cystathionine beta-lyase, eukaryotic.


ensembl_gene_id: PYK22_00081
symbol: CDM64089.1
gene_biotype: protein_coding
description:
  Iron-sulfur cluster repair di-iron protein; Di-iron-containing protein involved in the repair of iron- sulfur clusters; Belongs to the RIC family.


ensembl_gene_id: PYK22_00083
symbol: CDM64091.1
gene_biotype: protein_coding
description:
  Outer membrane receptor for ferrienterochelin and colicins; PFAM: Carboxypeptidase regulatory-like domain.


ensembl_gene_id: PYK22_00086
symbol: CDM64094.1
gene_biotype: protein_coding
description:
  PAS domain S-box; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; PAS domain; TIGRFAM: PAS domain S-box.


ensembl_gene_id: PYK22_00090
symbol: coaX
gene_biotype: protein_coding
description:
  Pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.


ensembl_gene_id: PYK22_00092
symbol: CDM64100.1
gene_biotype: protein_coding
description:
  PFAM: Periplasmic binding protein domain; TIGRFAM: D-xylose ABC transporter, substrate-binding protein.


ensembl_gene_id: PYK22_00093
symbol: rbsA
gene_biotype: protein_coding
description:
  Xylose ABC transporter ATP-binding protein; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family.


ensembl_gene_id: PYK22_00094
symbol: CDM64102.1
gene_biotype: protein_coding
description:
  Xylose ABC transporter membrane protein; PFAM: Branched-chain amino acid transport system / permease component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: PYK22_00095
symbol: CDM64103.1
gene_biotype: protein_coding
description:
  Transcriptional regulator/sugar kinase; PFAM: ROK family; TIGRFAM: ROK family protein (putative glucokinase).


ensembl_gene_id: PYK22_00096
symbol: CDM64104.1
gene_biotype: protein_coding
description:
  PFAM: Glycosyl-hydrolase 97 N-terminal; Glycoside hydrolase 97; Glycosyl-hydrolase 97 C-terminal, oligomerisation.


ensembl_gene_id: PYK22_00097
symbol: CDM64105.1
gene_biotype: protein_coding
description:
  Uncharacterized domain HDIG-containing protein; PFAM: HD domain; 7TM-HD extracellular; 7TM receptor with intracellular HD hydrolase; TIGRFAM: uncharacterized domain HDIG.


ensembl_gene_id: PYK22_00098
symbol: hflX
gene_biotype: protein_coding
description:
  GTP-binding protein HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.


ensembl_gene_id: PYK22_00101
symbol: trpS
gene_biotype: protein_coding
description:
  tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: PYK22_00102
symbol: CDM64110.1
gene_biotype: protein_coding
description:
  Condensin subunit ScpA; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.


ensembl_gene_id: PYK22_00103
symbol: CDM64111.1
gene_biotype: protein_coding
description:
  Condensin subunit ScpB; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.


ensembl_gene_id: PYK22_00104
symbol: CDM64112.1
gene_biotype: protein_coding
description:
  Ribosomal large subunit pseudouridine synthase B; PFAM: RNA pseudouridylate synthase; S4 domain; TIGRFAM: pseudouridine synthase; Belongs to the pseudouridine synthase RsuA family.


ensembl_gene_id: PYK22_00107
symbol: CDM64115.1
gene_biotype: protein_coding
description:
  2'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family.


ensembl_gene_id: PYK22_00110
symbol: CDM64118.1
gene_biotype: protein_coding
description:
  PFAM: Glycosyl hydrolase family 3 C-terminal domain; Glycosyl hydrolase family 3 N terminal domain; Fibronectin type III-like domain; Belongs to the glycosyl hydrolase 3 family.


ensembl_gene_id: PYK22_00116
symbol: CDM64124.1
gene_biotype: protein_coding
description:
  Predicted PLP-dependent enzyme possibly involved in cell wall biogenesis; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase family; Belongs to the DegT/DnrJ/EryC1 family.


ensembl_gene_id: PYK22_00119
symbol: CDM64127.1
gene_biotype: protein_coding
description:
  4-aminobutyrate aminotransferase family protein; PFAM: Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: PYK22_00120
symbol: CDM64128.1
gene_biotype: protein_coding
description:
  PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: Haloacid Dehalogenase superfamily, subfamily IB, phosphoserine phosphatase-like; 2,3-diketo-5-methylthio-1-phosphopentane phosphatase.


ensembl_gene_id: PYK22_00122
symbol: CDM64130.1
gene_biotype: protein_coding
description:
  UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase; PFAM: Glycosyl transferases group 1; Monogalactosyldiacylglycerol (MGDG) synthase.


ensembl_gene_id: PYK22_00128
symbol: CDM64136.1
gene_biotype: protein_coding
description:
  Non-ribosomal peptide synthase, dehydrogenase domain-containing protein; PFAM: Male sterility protein.


ensembl_gene_id: PYK22_00129
symbol: CDM64137.1
gene_biotype: protein_coding
description:
  PFAM: Beta-ketoacyl synthase, N-terminal domain; Beta-ketoacyl synthase, C-terminal domain; TIGRFAM: beta-ketoacyl-acyl-carrier-protein synthase II; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: PYK22_00130
symbol: CDM64138.1
gene_biotype: protein_coding
description:
  PFAM: Beta-ketoacyl synthase, N-terminal domain; Beta-ketoacyl synthase, C-terminal domain; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: PYK22_00135
symbol: CDM64143.1
gene_biotype: protein_coding
description:
  Two component transcriptional regulator, winged helix family; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.


ensembl_gene_id: PYK22_00136
symbol: CDM64144.1
gene_biotype: protein_coding
description:
  PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phospho-acceptor) domain; TIGRFAM: heavy metal sensor kinase.


ensembl_gene_id: PYK22_00138
symbol: CDM64146.1
gene_biotype: protein_coding
description:
  PFAM: HlyD family secretion protein; TIGRFAM: RND family efflux transporter, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: PYK22_00139
symbol: CDM64147.1
gene_biotype: protein_coding
description:
  PFAM: AcrB/AcrD/AcrF family; TIGRFAM: heavy metal efflux pump, CzcA family; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: PYK22_00144
symbol: CDM64152.1
gene_biotype: protein_coding
description:
  Transposase, IS605 OrfB family, central region; PFAM: Putative transposase DNA-binding domain; Probable transposase; TIGRFAM: transposase, IS605 OrfB family, central region; transposase, putative, N-terminal domain.


ensembl_gene_id: PYK22_00148
symbol: CDM64156.1
gene_biotype: protein_coding
description:
  Zn-dependent oxidoreductase, NADPH:quinone reductase; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase.


ensembl_gene_id: PYK22_00150
symbol: CDM64158.1
gene_biotype: protein_coding
description:
  Predicted oxidoreductase, aryl-alcohol dehydrogenase like protein; PFAM: Aldo/keto reductase family.


ensembl_gene_id: PYK22_00153
symbol: CDM64161.1
gene_biotype: protein_coding
description:
  PFAM: Haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E.


ensembl_gene_id: PYK22_00163
symbol: CDM64171.1
gene_biotype: protein_coding
description:
  Beta-galactosidase/beta-glucuronidase; PFAM: Glycosyl hydrolases family 2, TIM barrel domain; Glycosyl hydrolases family 2; Glycosyl hydrolases family 2, sugar binding domain; Belongs to the glycosyl hydrolase 2 family.


ensembl_gene_id: PYK22_00164
symbol: CDM64172.1
gene_biotype: protein_coding
description:
  Beta-galactosidase/beta-glucuronidase; PFAM: F5/8 type C domain; Glycosyl hydrolases family 2, TIM barrel domain; Glycosyl hydrolases family 2, sugar binding domain; Belongs to the glycosyl hydrolase 2 family.


ensembl_gene_id: PYK22_00165
symbol: CDM64173.1
gene_biotype: protein_coding
description:
  Rhamnulose-1-phosphate aldolase/alcohol dehydrogenase; PFAM: Class II Aldolase and Adducin N-terminal domain; short chain dehydrogenase; TIGRFAM: rhamnulose-1-phosphate aldolase/alcohol dehydrogenase.


ensembl_gene_id: PYK22_00166
symbol: CDM64174.1
gene_biotype: protein_coding
description:
  PFAM: Xylose isomerase-like TIM barrel; TIGRFAM: L-rhamnose isomerase, Streptomyces subtype; L-rhamnose catabolism isomerase, Pseudomonas stutzeri subtype.


ensembl_gene_id: PYK22_00167
symbol: CDM64175.1
gene_biotype: protein_coding
description:
  PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain.


ensembl_gene_id: PYK22_00168
symbol: CDM64176.1
gene_biotype: protein_coding
description:
  Ribulose-5-phosphate 4-epimerase-like epimerase or aldolase; PFAM: Class II Aldolase and Adducin N-terminal domain.


ensembl_gene_id: PYK22_00169
symbol: rbsA-2
gene_biotype: protein_coding
description:
  Monosaccharide ABC transporter ATP-binding protein, CUT2 family; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family.


ensembl_gene_id: PYK22_00170
symbol: CDM64178.1
gene_biotype: protein_coding
description:
  Monosaccharide ABC transporter membrane protein, CUT2 family; PFAM: Branched-chain amino acid transport system / permease component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: PYK22_00171
symbol: CDM64179.1
gene_biotype: protein_coding
description:
  PFAM: Periplasmic binding protein domain; Branched-chain amino acid transport system / permease component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: PYK22_00178
symbol: CDM64186.1
gene_biotype: protein_coding
description:
  Dehydrogenase of unknown specificity, short-chain alcohol dehydrogenase like; PFAM: Enoyl-(Acyl carrier protein) reductase.


ensembl_gene_id: PYK22_00191
symbol: CDM64199.1
gene_biotype: protein_coding
description:
  PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, middle domain; Acyl-CoA dehydrogenase, N-terminal domain.


ensembl_gene_id: PYK22_00193
symbol: CDM64201.1
gene_biotype: protein_coding
description:
  methylmalonyl-CoA epimerase; PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; TIGRFAM: methylmalonyl-CoA epimerase.


ensembl_gene_id: PYK22_00196
symbol: mtnP
gene_biotype: protein_coding
description:
  Methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.


ensembl_gene_id: PYK22_00201
symbol: CDM64209.1
gene_biotype: protein_coding
description:
  TIGR00730 family protein; PFAM: Possible lysine decarboxylase; TIGRFAM: TIGR00725 family protein; TIGR00730 family protein; Belongs to the LOG family.


ensembl_gene_id: PYK22_00208
symbol: CDM64216.1
gene_biotype: protein_coding
description:
  Two component, sigma54 specific, transcriptional regulator, Fis family; PFAM: Response regulator receiver domain; Bacterial regulatory protein, Fis family; Sigma-54 interaction domain.


ensembl_gene_id: PYK22_00209
symbol: CDM64217.1
gene_biotype: protein_coding
description:
  uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.


ensembl_gene_id: PYK22_00210
symbol: hemC
gene_biotype: protein_coding
description:
  Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.


ensembl_gene_id: PYK22_00211
symbol: hemA
gene_biotype: protein_coding
description:
  glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).


ensembl_gene_id: PYK22_00216
symbol: CDM64224.1
gene_biotype: protein_coding
description:
  Membrane protein implicated in regulation of membrane protease activity; PFAM: NfeD-like C-terminal, partner-binding.


ensembl_gene_id: PYK22_00219
symbol: CDM64227.1
gene_biotype: protein_coding
description:
  Cysteine synthase A; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.


ensembl_gene_id: PYK22_00220
symbol: CDM64228.1
gene_biotype: protein_coding
description:
  PFAM: Cytidylyltransferase; TIGRFAM: 3-deoxy-D-manno-octulosonate cytidylyltransferase; Belongs to the KdsB family.


ensembl_gene_id: PYK22_00221
symbol: pyrG
gene_biotype: protein_coding
description:
  CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.


ensembl_gene_id: PYK22_00222
symbol: kdsA
gene_biotype: protein_coding
description:
  PFAM: DAHP synthetase I family; TIGRFAM: 3-deoxy-8-phosphooctulonate synthase; Belongs to the KdsA family.


ensembl_gene_id: PYK22_00224
symbol: CDM64232.1
gene_biotype: protein_coding
description:
  PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family.


ensembl_gene_id: PYK22_00227
symbol: CDM64234.1
gene_biotype: protein_coding
description:
  Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).


ensembl_gene_id: PYK22_00229
symbol: CDM64236.1
gene_biotype: protein_coding
description:
  PFAM: Helix-hairpin-helix motif; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat region.


ensembl_gene_id: PYK22_00231
symbol: CDM64238.1
gene_biotype: protein_coding
description:
  Cation/multidrug efflux pump; PFAM: AcrB/AcrD/AcrF family; TIGRFAM: heavy metal efflux pump, CzcA family; The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: PYK22_00240
symbol: CDM64247.1
gene_biotype: protein_coding
description:
  acetyl-CoA acetyltransferase; PFAM: Thiolase, C-terminal domain; Thiolase, N-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases; Belongs to the thiolase-like superfamily. Thiolase family.


ensembl_gene_id: PYK22_00243
symbol: ilvE
gene_biotype: protein_coding
description:
  Branched chain amino acid aminotransferase apoenzyme; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: PYK22_00244
symbol: CDM64251.1
gene_biotype: protein_coding
description:
  Zn-dependent dipeptidase, microsomal dipeptidase; PFAM: Membrane dipeptidase (Peptidase family M19).


ensembl_gene_id: PYK22_00246
symbol: CDM64253.1
gene_biotype: protein_coding
description:
  ABC-type multidrug transport system, ATPase and permease component; PFAM: ABC transporter; ABC transporter transmembrane region.


ensembl_gene_id: PYK22_00250
symbol: CDM64257.1
gene_biotype: protein_coding
description:
  Predicted methylated DNA-protein cysteine methyltransferase; PFAM: 6-O-methylguanine DNA methyltransferase, DNA binding domain.


ensembl_gene_id: PYK22_00252
symbol: mqnA
gene_biotype: protein_coding
description:
  Predicted periplasmic solute-binding protein; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).


ensembl_gene_id: PYK22_00253
symbol: mqnC
gene_biotype: protein_coding
description:
  De-hypoxanthine futalosine cyclase; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).


ensembl_gene_id: PYK22_00254
symbol: CDM64261.1
gene_biotype: protein_coding
description:
  PAS domain S-box; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phospho-acceptor) domain; PAS fold; TIGRFAM: PAS domain S-box.


ensembl_gene_id: PYK22_00255
symbol: CDM64262.1
gene_biotype: protein_coding
description:
  PFAM: Amylo-alpha-1,6-glucosidase; Glycogen debranching enzyme N terminal; TIGRFAM: glycogen debranching enzyme, archaeal type, putative.


ensembl_gene_id: PYK22_00256
symbol: CDM64263.1
gene_biotype: protein_coding
description:
  Predicted RNA-binding protein, snRNP like protein; PFAM: Domain of unknown function (DUF814); Fibronectin-binding protein A N-terminus (FbpA).


ensembl_gene_id: PYK22_00264
symbol: CDM64271.1
gene_biotype: protein_coding
description:
  rRNA methylase, putative, group 3; PFAM: SpoU rRNA Methylase family; RNA 2'-O ribose methyltransferase substrate binding; TIGRFAM: rRNA methylase, putative, group 3; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.


ensembl_gene_id: PYK22_00266
symbol: aroE
gene_biotype: protein_coding
description:
  3-dehydroquinate dehydratase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).


ensembl_gene_id: PYK22_00267
symbol: CDM64274.1
gene_biotype: protein_coding
description:
  Dinucleotide-utilizing enzyme possibly involved in molybdopterin or thiamin biosynthesis; PFAM: MoeZ/MoeB domain; ThiF family.


ensembl_gene_id: PYK22_00276
symbol: CDM64283.1
gene_biotype: protein_coding
description:
  PFAM: E1-E2 ATPase; Heavy-metal-associated domain; haloacid dehalogenase-like hydrolase; TIGRFAM: copper-(or silver)-translocating P-type ATPase; heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase.


ensembl_gene_id: PYK22_00280
symbol: CDM64287.1
gene_biotype: protein_coding
description:
  Signal transduction histidine kinase, nitrogen specific; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Domain of unknown function (DUF4118); His Kinase A (phospho-acceptor) domain.


ensembl_gene_id: PYK22_00282
symbol: hmuV
gene_biotype: protein_coding
description:
  ABC-type hemin transport system, ATPase component; Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system.


ensembl_gene_id: PYK22_00283
symbol: CDM64290.1
gene_biotype: protein_coding
description:
  ABC-type Fe3+-siderophore transport system, permease component; PFAM: FecCD transport family; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: PYK22_00286
symbol: CDM64293.1
gene_biotype: protein_coding
description:
  Outer membrane receptor for ferrienterochelin and colicins; PFAM: TonB dependent receptor; TonB-dependent Receptor Plug Domain; Carboxypeptidase regulatory-like domain.


ensembl_gene_id: PYK22_00290
symbol: CDM64297.1
gene_biotype: protein_coding
description:
  Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS-like protein; PFAM: 2Fe-2S iron-sulfur cluster binding domain; [2Fe-2S] binding domain; TIGRFAM: 4-hydroxybenzoyl-CoA reductase, gamma subunit.


ensembl_gene_id: PYK22_00291
symbol: panC
gene_biotype: protein_coding
description:
  Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.


ensembl_gene_id: PYK22_00292
symbol: panB
gene_biotype: protein_coding
description:
  Ketopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.


ensembl_gene_id: PYK22_00293
symbol: CDM64300.1
gene_biotype: protein_coding
description:
  PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK); TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase.


ensembl_gene_id: PYK22_00298
symbol: CDM64305.1
gene_biotype: protein_coding
description:
  Hypothetical protein; PFAM: Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella; ASPIC and UnbV.


ensembl_gene_id: PYK22_00301
symbol: CDM64308.1
gene_biotype: protein_coding
description:
  Hypothetical protein; PFAM: Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella; ASPIC and UnbV; Tetratricopeptide repeat; TPR repeat.


ensembl_gene_id: PYK22_00304
symbol: CDM64311.1
gene_biotype: protein_coding
description:
  Cytochrome c, mono-and diheme variants family; PFAM: Cytochrome C oxidase, cbb3-type, subunit III; TIGRFAM: cytochrome c oxidase, cbb3-type, subunit III.


ensembl_gene_id: PYK22_00306
symbol: CDM64313.1
gene_biotype: protein_coding
description:
  FAD/FMN-dependent dehydrogenase; PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain; TIGRFAM: glycolate oxidase, subunit GlcD.


ensembl_gene_id: PYK22_00308
symbol: CDM64315.1
gene_biotype: protein_coding
description:
  Amino acid/polyamine/organocation transporter, APC superfamily (TC 2.A.3); PFAM: Amino acid permease.


ensembl_gene_id: PYK22_00315
symbol: CDM64322.1
gene_biotype: protein_coding
description:
  Dehydrogenase of unknown specificity, short-chain alcohol dehydrogenase like; PFAM: short chain dehydrogenase.


ensembl_gene_id: PYK22_00318
symbol: CDM64325.1
gene_biotype: protein_coding
description:
  Predicted Zn-dependent peptidase; PFAM: Peptidase M16 inactive domain; Insulinase (Peptidase family M16).


ensembl_gene_id: PYK22_00337
symbol: CDM64344.1
gene_biotype: protein_coding
description:
  Outer membrane receptor for ferrienterochelin and colicins; PFAM: TonB-dependent Receptor Plug Domain; Carboxypeptidase regulatory-like domain.


ensembl_gene_id: PYK22_00338
symbol: CDM64345.1
gene_biotype: protein_coding
description:
  Glycogen debranching enzyme; PFAM: Bacterial alpha-L-rhamnosidase; Alpha-L-rhamnosidase N-terminal domain.


ensembl_gene_id: PYK22_00340
symbol: CDM64347.1
gene_biotype: protein_coding
description:
  Peptide chain release factor 1 (eRF1); PFAM: eRF1 domain 3; Protein required for attachment to host cells.


ensembl_gene_id: PYK22_00342
symbol: CDM64349.1
gene_biotype: protein_coding
description:
  Uncharacterized AP superfamily protein; PFAM: Type I phosphodiesterase / nucleotide pyrophosphatase.


ensembl_gene_id: PYK22_00343
symbol: leuS
gene_biotype: protein_coding
description:
  PFAM: Leucyl-tRNA synthetase, Domain 2; tRNA synthetases class I (I, L, M and V); Anticodon-binding domain of tRNA; TIGRFAM: leucyl-tRNA synthetase, eubacterial and mitochondrial family; Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: PYK22_00344
symbol: nfo
gene_biotype: protein_coding
description:
  Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.


ensembl_gene_id: PYK22_00345
symbol: ribA
gene_biotype: protein_coding
description:
  GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family.


ensembl_gene_id: PYK22_00351
symbol: CDM64358.1
gene_biotype: protein_coding
description:
  Predicted rRNA methylase SpoU family; Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.


ensembl_gene_id: PYK22_00360
symbol: CDM64367.1
gene_biotype: protein_coding
description:
  PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: PYK22_00366
symbol: CDM64373.1
gene_biotype: protein_coding
description:
  NAD(P)H-nitrite reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Reductase C-terminal; Rieske [2Fe-2S] domain.


ensembl_gene_id: PYK22_00372
symbol: xylA
gene_biotype: protein_coding
description:
  PFAM: Xylose isomerase-like TIM barrel; TIGRFAM: xylose isomerase, Arthrobacter type; Belongs to the xylose isomerase family.


ensembl_gene_id: PYK22_00374
symbol: xylB
gene_biotype: protein_coding
description:
  Xylulokinase; PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain; TIGRFAM: D-xylulose kinase.


ensembl_gene_id: PYK22_00381
symbol: CDM64388.1
gene_biotype: protein_coding
description:
  PFAM: UbiA prenyltransferase family; TIGRFAM: putative 4-hydroxybenzoate polyprenyltransferase; Belongs to the UbiA prenyltransferase family.


ensembl_gene_id: PYK22_00382
symbol: mqnE
gene_biotype: protein_coding
description:
  Putative menaquinone biosynthesis protein, SCO4494 family; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.


ensembl_gene_id: PYK22_00384
symbol: mqnD
gene_biotype: protein_coding
description:
  1,4-dihydroxy-6-naphthoate synthase; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily.


ensembl_gene_id: PYK22_00385
symbol: hisF
gene_biotype: protein_coding
description:
  Imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.


ensembl_gene_id: PYK22_00386
symbol: hisI
gene_biotype: protein_coding
description:
  PFAM: Phosphoribosyl-ATP pyrophosphohydrolase; Phosphoribosyl-AMP cyclohydrolase; TIGRFAM: phosphoribosyl-ATP pyrophosphohydrolase; In the N-terminal section; belongs to the PRA-CH family.


ensembl_gene_id: PYK22_00387
symbol: CDM64394.1
gene_biotype: protein_coding
description:
  PFAM: Inositol monophosphatase family; TIGRFAM: histidinol-phosphatase, inositol monophosphatase family.


ensembl_gene_id: PYK22_00389
symbol: surE
gene_biotype: protein_coding
description:
  5'-nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.


ensembl_gene_id: PYK22_00390
symbol: pcm
gene_biotype: protein_coding
description:
  protein-L-isoaspartate and D-aspartate O-methyltransferase; Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.


ensembl_gene_id: PYK22_00394
symbol: CDM64400.1
gene_biotype: protein_coding
description:
  Queuosine biosynthesis protein QueD; PFAM: 6-pyruvoyl tetrahydropterin synthase; TIGRFAM: queuosine biosynthesis protein QueD; 6-pyruvoyl tetrahydropterin synthase/QueD family protein.


ensembl_gene_id: PYK22_00395
symbol: CDM64401.1
gene_biotype: protein_coding
description:
  DNA helicase, Rad3; PFAM: Helicase C-terminal domain; DEAD_2; DEAD/DEAH box helicase; TIGRFAM: DnaQ family exonuclease/DinG family helicase, putative.


ensembl_gene_id: PYK22_00396
symbol: glyA
gene_biotype: protein_coding
description:
  Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.


ensembl_gene_id: PYK22_00397
symbol: CDM64403.1
gene_biotype: protein_coding
description:
  PFAM: Ribose/Galactose Isomerase; TIGRFAM: ribose 5-phosphate isomerase B; sugar-phosphate isomerase, RpiB/LacA/LacB family.


ensembl_gene_id: PYK22_00398
symbol: proS
gene_biotype: protein_coding
description:
  prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...]


ensembl_gene_id: PYK22_00400
symbol: ubiX
gene_biotype: protein_coding
description:
  Polyprenyl p-hydroxybenzoate/phenylacrylic acid decarboxylase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family.


ensembl_gene_id: PYK22_00402
symbol: hisH
gene_biotype: protein_coding
description:
  Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.


ensembl_gene_id: PYK22_00404
symbol: hisD
gene_biotype: protein_coding
description:
  Histidinol-phosphate aminotransferase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.


ensembl_gene_id: PYK22_00405
symbol: hisG
gene_biotype: protein_coding
description:
  ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily.


ensembl_gene_id: PYK22_00406
symbol: hisZ
gene_biotype: protein_coding
description:
  ATP phosphoribosyltransferase, regulatory subunit; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.


ensembl_gene_id: PYK22_00408
symbol: CDM64414.1
gene_biotype: protein_coding
description:
  Phosphomannomutase; PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/phosphomannomutase, C-terminal domain; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I.


ensembl_gene_id: PYK22_00414
symbol: CDM64420.1
gene_biotype: protein_coding
description:
  DNA/RNA helicase, superfamily II, SNF2 family; PFAM: Helicase conserved C-terminal domain; Domain of unknown function (DUF3883); SNF2 family N-terminal domain.


ensembl_gene_id: PYK22_00415
symbol: CDM64421.1
gene_biotype: protein_coding
description:
  Glutathione synthase/ribosomal protein S6 modification enzyme (glutaminyl transferase); PFAM: ATP-grasp domain.


ensembl_gene_id: PYK22_00416
symbol: CDM64422.1
gene_biotype: protein_coding
description:
  Flavin-dependent oxidoreductase, F420-dependent methylene-tetrahydromethanopterin reductase; PFAM: Luciferase-like monooxygenase.


ensembl_gene_id: PYK22_00417
symbol: CDM64423.1
gene_biotype: protein_coding
description:
  enoyl-CoA hydratase/carnithine racemase; PFAM: Enoyl-CoA hydratase/isomerase family; Belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: PYK22_00418
symbol: CDM64424.1
gene_biotype: protein_coding
description:
  Predicted hydrolase or acyltransferase of alpha/beta superfamily; PFAM: Alpha/beta hydrolase family.


ensembl_gene_id: PYK22_00420
symbol: thiG
gene_biotype: protein_coding
description:
  Thiazole-phosphate synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.


ensembl_gene_id: PYK22_00423
symbol: nuoA
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit A; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family.


ensembl_gene_id: PYK22_00424
symbol: nuoB
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit B; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: PYK22_00425
symbol: nuoC
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit C; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 30 kDa subunit family.


ensembl_gene_id: PYK22_00427
symbol: nuoD
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family.


ensembl_gene_id: PYK22_00428
symbol: CDM64434.1
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit E; PFAM: Thioredoxin-like [2Fe-2S] ferredoxin; TIGRFAM: NADH-quinone oxidoreductase, E subunit.


ensembl_gene_id: PYK22_00429
symbol: CDM64435.1
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit F; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family.


ensembl_gene_id: PYK22_00430
symbol: CDM64436.1
gene_biotype: protein_coding
description:
  Uncharacterized anaerobic dehydrogenase; PFAM: 2Fe-2S iron-sulfur cluster binding domain; Molybdopterin oxidoreductase; 4Fe-4S dicluster domain; NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Molybdopterin oxidoreductase Fe4S4 domain; TIGRFAM: NADH-quinone oxidoreductase, chain G.


ensembl_gene_id: PYK22_00431
symbol: nuoH
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit H; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.


ensembl_gene_id: PYK22_00432
symbol: CDM64438.1
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit J; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: PYK22_00433
symbol: nuoK
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit K; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family.


ensembl_gene_id: PYK22_00434
symbol: CDM64440.1
gene_biotype: protein_coding
description:
  PFAM: NADH-Ubiquinone oxidoreductase (complex I) subunit C-terminus; NADH-Ubiquinone/plastoquinone (complex I), various chains; NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain L.


ensembl_gene_id: PYK22_00435
symbol: CDM64441.1
gene_biotype: protein_coding
description:
  PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains; NADH-ubiquinone oxidoreductase chain 4, amino terminus; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain M.


ensembl_gene_id: PYK22_00437
symbol: nuoN
gene_biotype: protein_coding
description:
  Proton-translocating NADH-quinone oxidoreductase, chain N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family.


ensembl_gene_id: PYK22_00440
symbol: CDM64446.1
gene_biotype: protein_coding
description:
  PFAM: Aminopeptidase P, N-terminal domain; Metallopeptidase family M24; Belongs to the peptidase M24B family.


ensembl_gene_id: PYK22_00445
symbol: CDM64451.1
gene_biotype: protein_coding
description:
  PFAM: Sodium:solute symporter family; TIGRFAM: transporter, SSS family; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: PYK22_00448
symbol: prfA
gene_biotype: protein_coding
description:
  Bacterial peptide chain release factor 1 (bRF-1); Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.


ensembl_gene_id: PYK22_00455
symbol: carB
gene_biotype: protein_coding
description:
  PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; MGS-like domain; Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Carbamoyl-phosphate synthase L chain, N-terminal domain; TIGRFAM: carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family.


ensembl_gene_id: PYK22_00457
symbol: CDM64463.1
gene_biotype: protein_coding
description:
  Predicted dehydrogenase; PFAM: Oxidoreductase family, C-terminal alpha/beta domain; Oxidoreductase family, NAD-binding Rossmann fold; Zinc-binding dehydrogenase.


ensembl_gene_id: PYK22_00461
symbol: CDM64467.1
gene_biotype: protein_coding
description:
  TonB family protein; PFAM: Gram-negative bacterial TonB protein C-terminal; TIGRFAM: TonB family C-terminal domain.


ensembl_gene_id: PYK22_00462
symbol: rex
gene_biotype: protein_coding
description:
  AT-rich DNA-binding protein; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.


ensembl_gene_id: PYK22_00463
symbol: ruvA
gene_biotype: protein_coding
description:
  Holliday junction DNA helicase subunit RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.


ensembl_gene_id: PYK22_00464
symbol: ruvB
gene_biotype: protein_coding
description:
  Holliday junction DNA helicase subunit RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.


ensembl_gene_id: PYK22_00465
symbol: queA
gene_biotype: protein_coding
description:
  S-adenosylmethionine--tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).


ensembl_gene_id: PYK22_00470
symbol: CDM64476.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein, cofD-related; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family.


ensembl_gene_id: PYK22_00471
symbol: glmU
gene_biotype: protein_coding
description:
  UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.


ensembl_gene_id: PYK22_00472
symbol: glmS
gene_biotype: protein_coding
description:
  Glutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.


ensembl_gene_id: PYK22_00473
symbol: CDM64479.1
gene_biotype: protein_coding
description:
  Membrane protein TerC, possibly involved in tellurium resistance; PFAM: Integral membrane protein TerC family.


ensembl_gene_id: PYK22_00479
symbol: CDM64485.1
gene_biotype: protein_coding
description:
  ATPase involved in chromosome partitioning; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.


ensembl_gene_id: PYK22_00480
symbol: CDM64486.1
gene_biotype: protein_coding
description:
  PFAM: Iron-sulphur cluster biosynthesis; TIGRFAM: Iron-sulfur cluster assembly accessory protein; Belongs to the HesB/IscA family.


ensembl_gene_id: PYK22_00481
symbol: CDM64487.1
gene_biotype: protein_coding
description:
  Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrF; PFAM: 2Fe-2S iron-sulfur cluster binding domain.


ensembl_gene_id: PYK22_00483
symbol: CDM64489.1
gene_biotype: protein_coding
description:
  Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.


ensembl_gene_id: PYK22_00488
symbol: CDM64494.1
gene_biotype: protein_coding
description:
  Folate-binding protein YgfZ; PFAM: Glycine cleavage T-protein C-terminal barrel domain; Aminomethyltransferase folate-binding domain; TIGRFAM: folate-binding protein YgfZ; glycine cleavage system T protein; Belongs to the GcvT family.


ensembl_gene_id: PYK22_00493
symbol: CDM64499.1
gene_biotype: protein_coding
description:
  PFAM: Uncharacterised P-loop hydrolase UPF0079; TIGRFAM: tRNA threonylcarbamoyl adenosine modification protein YjeE.


ensembl_gene_id: PYK22_00494
symbol: CDM64500.1
gene_biotype: protein_coding
description:
  Aminodeoxychorismate synthase, component I; PFAM: Aminotransferase class IV; chorismate binding enzyme; TIGRFAM: aminodeoxychorismate synthase, component I, bacterial clade.


ensembl_gene_id: PYK22_00495
symbol: nnrD
gene_biotype: protein_coding
description:
  yjeF-like protein, hydroxyethylthiazole kinase-related; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.  Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydrata [...]


ensembl_gene_id: PYK22_00498
symbol: CDM64504.1
gene_biotype: protein_coding
description:
  Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains; PFAM: Response regulator receiver domain; Bacterial regulatory protein, Fis family; Sigma-54 interaction domain.


ensembl_gene_id: PYK22_00499
symbol: CDM64505.1
gene_biotype: protein_coding
description:
  PAS domain S-box; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phospho-acceptor) domain; PAS fold; TIGRFAM: PAS domain S-box.


ensembl_gene_id: PYK22_00500
symbol: CDM64506.1
gene_biotype: protein_coding
description:
  PFAM: HD domain; GGDEF domain; GAF domain; TIGRFAM: uncharacterized domain HDIG; diguanylate cyclase (GGDEF) domain.


ensembl_gene_id: PYK22_00501
symbol: CDM64507.1
gene_biotype: protein_coding
description:
  PFAM: Prolyl oligopeptidase family; Dipeptidyl peptidase IV (DPP IV) N-terminal region; WD40-like Beta Propeller Repeat.


ensembl_gene_id: PYK22_00508
symbol: CDM64514.1
gene_biotype: protein_coding
description:
  Sulfite oxidase-like oxidoreductase; PFAM: Mo-co oxidoreductase dimerisation domain; Oxidoreductase molybdopterin binding domain.


ensembl_gene_id: PYK22_00510
symbol: CDM64516.1
gene_biotype: protein_coding
description:
  PFAM: Riboflavin kinase; FAD synthetase; TIGRFAM: riboflavin kinase/FMN adenylyltransferase; Belongs to the ribF family.


ensembl_gene_id: PYK22_00513
symbol: CDM64519.1
gene_biotype: protein_coding
description:
  MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase domain; TIGRFAM: MazG family protein.


ensembl_gene_id: PYK22_00517
symbol: CDM64523.1
gene_biotype: protein_coding
description:
  PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; TIGRFAM: zinc-binding alcohol dehydrogenase family protein.


ensembl_gene_id: PYK22_00519
symbol: rlmN
gene_biotype: protein_coding
description:
  23S rRNA m(2)A-2503 methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family.


ensembl_gene_id: PYK22_00522
symbol: CDM64528.1
gene_biotype: protein_coding
description:
  DNA-binding protein with winged-HTH domain; PFAM: Transcriptional regulatory protein, C terminal; TPR repeat.


ensembl_gene_id: PYK22_00523
symbol: CDM64529.1
gene_biotype: protein_coding
description:
  PEP-CTERM putative exosortase interaction domain-containing protein; PFAM: PEP-CTERM motif; TIGRFAM: PEP-CTERM protein-sorting domain.


ensembl_gene_id: PYK22_00527
symbol: CDM64533.1
gene_biotype: protein_coding
description:
  PFAM: S-adenosylmethionine synthetase, C-terminal domain; S-adenosylmethionine synthetase, central domain; S-adenosylmethionine synthetase, N-terminal domain; TIGRFAM: S-adenosylmethionine synthetase; Belongs to the AdoMet synthase family.


ensembl_gene_id: PYK22_00530
symbol: lig
gene_biotype: protein_coding
description:
  ATP-dependent DNA ligase I; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.


ensembl_gene_id: PYK22_00534
symbol: CDM64540.1
gene_biotype: protein_coding
description:
  Mn2+/Fe2_transporter, NRAMP family; PFAM: Natural resistance-associated macrophage protein; TIGRFAM: NRAMP (natural resistance-associated macrophage protein) metal ion transporters.


ensembl_gene_id: PYK22_00535
symbol: CDM64541.1
gene_biotype: protein_coding
description:
  Heat shock protein Hsp20; PFAM: Hsp20/alpha crystallin family; Belongs to the small heat shock protein (HSP20) family.


ensembl_gene_id: PYK22_00536
symbol: CDM64542.1
gene_biotype: protein_coding
description:
  Molecular chaperone (small heat shock protein); PFAM: Hsp20/alpha crystallin family; Belongs to the small heat shock protein (HSP20) family.


ensembl_gene_id: PYK22_00537
symbol: grpE
gene_biotype: protein_coding
description:
  Molecular chaperone GrpE (heat shock protein); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  [...]


ensembl_gene_id: PYK22_00539
symbol: CDM64545.1
gene_biotype: protein_coding
description:
  ATPase with chaperone activity, ATP-binding subunit; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; Clp amino terminal domain; ATPase family associated with various cellular activities (AAA); Belongs to the ClpA/ClpB family.


ensembl_gene_id: PYK22_00544
symbol: rplS
gene_biotype: protein_coding
description:
  LSU ribosomal protein L19P; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.


ensembl_gene_id: PYK22_00545
symbol: trmD
gene_biotype: protein_coding
description:
  tRNA (guanine-N1)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.


ensembl_gene_id: PYK22_00546
symbol: rimM
gene_biotype: protein_coding
description:
  16S rRNA processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family.


ensembl_gene_id: PYK22_00548
symbol: rpsP
gene_biotype: protein_coding
description:
  PFAM: Ribosomal protein S16; TIGRFAM: ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family.


ensembl_gene_id: PYK22_00549
symbol: ffh
gene_biotype: protein_coding
description:
  Signal recognition particle subunit FFH/SRP54 (srp54); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.


ensembl_gene_id: PYK22_00551
symbol: hrcA
gene_biotype: protein_coding
description:
  Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons.


ensembl_gene_id: PYK22_00554
symbol: dnaJ
gene_biotype: protein_coding
description:
  Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]


ensembl_gene_id: PYK22_00559
symbol: CDM64565.1
gene_biotype: protein_coding
description:
  Fructose-1,6-bisphosphatase, class II; PFAM: Bacterial fructose-1,6-bisphosphatase, glpX-encoded; TIGRFAM: fructose-1,6-bisphosphatase, class II.


ensembl_gene_id: PYK22_00561
symbol: CDM64567.1
gene_biotype: protein_coding
description:
  tRNA nucleotidyltransferase/poly(A) polymerase; PFAM: HD domain; Poly A polymerase head domain; Probable RNA and SrmB- binding site of polymerase A; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.


ensembl_gene_id: PYK22_00564
symbol: CDM64570.1
gene_biotype: protein_coding
description:
  Putative TIM-barrel protein, nifR3 family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.


ensembl_gene_id: PYK22_00565
symbol: murJ
gene_biotype: protein_coding
description:
  Integral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.


ensembl_gene_id: PYK22_00572
symbol: CDM64578.1
gene_biotype: protein_coding
description:
  TIGR01777 family protein; PFAM: NAD dependent epimerase/dehydratase family; Domain of unknown function (DUF1731); TIGRFAM: TIGR01777 family protein.


ensembl_gene_id: PYK22_00573
symbol: murE
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.


ensembl_gene_id: PYK22_00575
symbol: CDM64581.1
gene_biotype: protein_coding
description:
  N-acyl-D-aspartate/D-glutamate deacylase; PFAM: Amidohydrolase; D-aminoacylase, C-terminal region; Amidohydrolase family.


ensembl_gene_id: PYK22_00578
symbol: CDM64584.1
gene_biotype: protein_coding
description:
  PFAM: Sodium:solute symporter family; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: PYK22_00581
symbol: CDM64587.1
gene_biotype: protein_coding
description:
  Putative N-acetylmannosamine-6-phosphate epimerase; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P).


ensembl_gene_id: PYK22_00584
symbol: CDM64590.1
gene_biotype: protein_coding
description:
  N-methylhydantoinase A/acetone carboxylase, beta subunit; PFAM: Hydantoinase/oxoprolinase; Hydantoinase/oxoprolinase N-terminal region.


ensembl_gene_id: PYK22_00586
symbol: CDM64592.1
gene_biotype: protein_coding
description:
  PFAM: Glycosyl hydrolase family 3 C-terminal domain; Glycosyl hydrolase family 3 N terminal domain; Belongs to the glycosyl hydrolase 3 family.


ensembl_gene_id: PYK22_00590
symbol: CDM64596.1
gene_biotype: protein_coding
description:
  N-acetyl-beta-hexosaminidase; PFAM: Glycosyl hydrolase family 20, catalytic domain; Glycosyl hydrolase family 20, domain 2.


ensembl_gene_id: PYK22_00592
symbol: CDM64598.1
gene_biotype: protein_coding
description:
  Alpha-mannosidase; PFAM: Glycosyl hydrolases family 38 C-terminal domain; Glycosyl hydrolases family 38 N-terminal domain; Alpha mannosidase, middle domain.


ensembl_gene_id: PYK22_00593
symbol: CDM64599.1
gene_biotype: protein_coding
description:
  PFAM: Bacterial regulatory proteins, gntR family; UTRA domain; TIGRFAM: phosphonates metabolism transcriptional regulator PhnF.


ensembl_gene_id: PYK22_00596
symbol: msrA
gene_biotype: protein_coding
description:
  methionine-S-sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.


ensembl_gene_id: PYK22_00603
symbol: CDM64609.1
gene_biotype: protein_coding
description:
  Predicted dehydrogenase; PFAM: Oxidoreductase family, C-terminal alpha/beta domain; Oxidoreductase family, NAD-binding Rossmann fold.


ensembl_gene_id: PYK22_00613
symbol: gyrA
gene_biotype: protein_coding
description:
  DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.


ensembl_gene_id: PYK22_00616
symbol: moaA
gene_biotype: protein_coding
description:
  Cyclic pyranopterin monophosphate synthase subunit MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.


ensembl_gene_id: PYK22_00618
symbol: thiC
gene_biotype: protein_coding
description:
  Hydroxymethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.


ensembl_gene_id: PYK22_00623
symbol: CDM64628.1
gene_biotype: protein_coding
description:
  Sulfate ABC transporter, permease protein CysT; Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.


ensembl_gene_id: PYK22_00624
symbol: CDM64629.1
gene_biotype: protein_coding
description:
  Sulfate ABC transporter, permease protein CysW; PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: sulfate ABC transporter, permease protein CysW; sulfate ABC transporter, permease protein.


ensembl_gene_id: PYK22_00625
symbol: cysA
gene_biotype: protein_coding
description:
  Sulfate ABC transporter, ATP-binding protein; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system.


ensembl_gene_id: PYK22_00631
symbol: purN
gene_biotype: protein_coding
description:
  Formyltetrahydrofolate-dependent phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.


ensembl_gene_id: PYK22_00632
symbol: purM
gene_biotype: protein_coding
description:
  Phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: phosphoribosylaminoimidazole synthetase.


ensembl_gene_id: PYK22_00636
symbol: purF
gene_biotype: protein_coding
description:
  Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.


ensembl_gene_id: PYK22_00639
symbol: CDM64644.1
gene_biotype: protein_coding
description:
  Theronine dehydrogenase-like Zn-dependent dehydrogenase; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase.


ensembl_gene_id: PYK22_00641
symbol: CDM64646.1
gene_biotype: protein_coding
description:
  PFAM: Trypsin-like peptidase domain; PDZ domain; TIGRFAM: periplasmic serine protease, Do/DeqQ family.


ensembl_gene_id: PYK22_00643
symbol: CDM64648.1
gene_biotype: protein_coding
description:
  PFAM: Alanine dehydrogenase/PNT, C-terminal domain; Alanine dehydrogenase/PNT, N-terminal domain; TIGRFAM: alanine dehydrogenase; Belongs to the AlaDH/PNT family.


ensembl_gene_id: PYK22_00645
symbol: CDM64650.1
gene_biotype: protein_coding
description:
  Fe-S oxidoreductase; PFAM: Protein of unknown function (DUF512); PDZ domain (Also known as DHR or GLGF); TIGRFAM: putative FeS-containing Cyanobacterial-specific oxidoreductase.


ensembl_gene_id: PYK22_00650
symbol: CDM64655.1
gene_biotype: protein_coding
description:
  PFAM: Formiminotransferase domain, N-terminal subdomain; Formiminotransferase domain; TIGRFAM: glutamate formiminotransferase.


ensembl_gene_id: PYK22_00651
symbol: tyrS
gene_biotype: protein_coding
description:
  tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.


ensembl_gene_id: PYK22_00652
symbol: panD
gene_biotype: protein_coding
description:
  L-aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.


ensembl_gene_id: PYK22_00653
symbol: dapF
gene_biotype: protein_coding
description:
  Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.


ensembl_gene_id: PYK22_00654
symbol: pyrF
gene_biotype: protein_coding
description:
  Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.


ensembl_gene_id: PYK22_00659
symbol: CDM64664.1
gene_biotype: protein_coding
description:
  Nicotinate-nucleotide pyrophosphorylase (carboxylating); PFAM: Quinolinate phosphoribosyl transferase, C-terminal domain; Quinolinate phosphoribosyl transferase, N-terminal domain; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family.


ensembl_gene_id: PYK22_00660
symbol: valS
gene_biotype: protein_coding
description:
  valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.


ensembl_gene_id: PYK22_00664
symbol: ispH
gene_biotype: protein_coding
description:
  4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.


ensembl_gene_id: PYK22_00667
symbol: secA
gene_biotype: protein_coding
description:
  Protein translocase subunit secA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family.


ensembl_gene_id: PYK22_00668
symbol: CDM64673.1
gene_biotype: protein_coding
description:
  Predicted Zn-dependent peptidase; PFAM: Peptidase M16 inactive domain; Insulinase (Peptidase family M16); Belongs to the peptidase M16 family.


ensembl_gene_id: PYK22_00669
symbol: CDM64674.1
gene_biotype: protein_coding
description:
  PFAM: Isocitrate/isopropylmalate dehydrogenase; TIGRFAM: isocitrate dehydrogenase, NAD-dependent, mitochondrial type; isopropylmalate/isohomocitrate dehydrogenases.


ensembl_gene_id: PYK22_00687
symbol: aroB
gene_biotype: protein_coding
description:
  3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).


ensembl_gene_id: PYK22_00689
symbol: ppa
gene_biotype: protein_coding
description:
  Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.


ensembl_gene_id: PYK22_00690
symbol: CDM64695.1
gene_biotype: protein_coding
description:
  Trypsin-like serine protease with C-terminal PDZ domain; PFAM: Trypsin-like peptidase domain; PDZ domain.


ensembl_gene_id: PYK22_00693
symbol: CDM64698.1
gene_biotype: protein_coding
description:
  Predicted aminopeptidase; PFAM: PA domain; Peptidase family M28; Transferrin receptor-like dimerisation domain.


ensembl_gene_id: PYK22_00695
symbol: CDM64700.1
gene_biotype: protein_coding
description:
  PFAM: Phage integrase, N-terminal SAM-like domain; Phage integrase family; TIGRFAM: integron integrase; Belongs to the 'phage' integrase family.


ensembl_gene_id: PYK22_00696
symbol: CDM64701.1
gene_biotype: protein_coding
description:
  Type I restriction-modification system methyltransferase subunit; PFAM: N-6 DNA Methylase; Type I restriction enzyme R protein N terminus (HSDR_N).


ensembl_gene_id: PYK22_00708
symbol: CDM64713.1
gene_biotype: protein_coding
description:
  Putative translation initiation inhibitor, yjgF family; PFAM: YjgF/chorismate_mutase-like, putative endoribonuclease.


ensembl_gene_id: PYK22_00712
symbol: hldD
gene_biotype: protein_coding
description:
  ADP-glyceromanno-heptose 6-epimerase precursor; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.


ensembl_gene_id: PYK22_00713
symbol: CDM64718.1
gene_biotype: protein_coding
description:
  Homospermidine synthase (spermidine-specific); PFAM: Deoxyhypusine synthase; TIGRFAM: deoxyhypusine synthase.


ensembl_gene_id: PYK22_00718
symbol: CDM64723.1
gene_biotype: protein_coding
description:
  AMP-forming long-chain acyl-CoA synthetase; PFAM: Phosphopantetheine attachment site; Male sterility protein; Acyltransferase; AMP-binding enzyme; AMP-binding enzyme C-terminal domain; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases.


ensembl_gene_id: PYK22_00720
symbol: CDM64725.1
gene_biotype: protein_coding
description:
  PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: HAD-superfamily subfamily IB hydrolase, TIGR01490; Haloacid Dehalogenase superfamily, subfamily IB, phosphoserine phosphatase-like.


ensembl_gene_id: PYK22_00725
symbol: CDM64730.1
gene_biotype: protein_coding
description:
  PMT family glycosyltransferase, 4-amino-4-deoxy-L-arabinose transferase; PFAM: Dolichyl-phosphate-mannose-protein mannosyltransferase.


ensembl_gene_id: PYK22_00728
symbol: CDM64733.1
gene_biotype: protein_coding
description:
  ABC-type transport system, involved in lipoprotein release, permease component; PFAM: MacB-like periplasmic core domain; FtsX-like permease family; Uncharacterised protein family (UPF0104).


ensembl_gene_id: PYK22_00733
symbol: CDM64738.1
gene_biotype: protein_coding
description:
  UTP-hexose-1-phosphate uridylyltransferase; PFAM: Galactose-1-phosphate uridyl transferase, C-terminal domain; Galactose-1-phosphate uridyl transferase, N-terminal domain; TIGRFAM: galactose-1-phosphate uridylyltransferase, family 1.


ensembl_gene_id: PYK22_00737
symbol: CDM64742.1
gene_biotype: protein_coding
description:
  Transcriptional regulator, AraC family; PFAM: Helix-turn-helix domain; AraC-like ligand binding domain.


ensembl_gene_id: PYK22_00742
symbol: CDM64747.1
gene_biotype: protein_coding
description:
  Dihydrodipicolinate synthase/N-acetylneuraminate lyase; PFAM: Dihydrodipicolinate synthetase family; Belongs to the DapA family.


ensembl_gene_id: PYK22_00753
symbol: CDM64758.1
gene_biotype: protein_coding
description:
  PFAM: Glycosyl hydrolases family 38 C-terminal domain; Glycosyl hydrolases family 38 N-terminal domain.


ensembl_gene_id: PYK22_00755
symbol: CDM64760.1
gene_biotype: protein_coding
description:
  Transcriptional regulator, DeoR family; PFAM: DeoR-like helix-turn-helix domain; DeoR C terminal sensor domain.


ensembl_gene_id: PYK22_00761
symbol: CDM64766.1
gene_biotype: protein_coding
description:
  PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) synthase III.


ensembl_gene_id: PYK22_00766
symbol: mltG
gene_biotype: protein_coding
description:
  Conserved hypothetical protein, YceG family; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.


ensembl_gene_id: PYK22_00767
symbol: CDM64772.1
gene_biotype: protein_coding
description:
  RNAse H-fold protein YqgF; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family.


ensembl_gene_id: PYK22_00768
symbol: CDM64773.1
gene_biotype: protein_coding
description:
  PFAM: Peptidase family S41; PDZ domain; TIGRFAM: C-terminal peptidase (prc); Belongs to the peptidase S41A family.


ensembl_gene_id: PYK22_00771
symbol: CDM64776.1
gene_biotype: protein_coding
description:
  Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM-like protein; PFAM: FAD binding domain in molybdopterin dehydrogenase; CO dehydrogenase flavoprotein C-terminal domain.


ensembl_gene_id: PYK22_00772
symbol: CDM64777.1
gene_biotype: protein_coding
description:
  Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL-like protein; PFAM: Molybdopterin-binding domain of aldehyde dehydrogenase; Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain.


ensembl_gene_id: PYK22_00773
symbol: CDM64778.1
gene_biotype: protein_coding
description:
  Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS-like protein; PFAM: 2Fe-2S iron-sulfur cluster binding domain; [2Fe-2S] binding domain; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence.


ensembl_gene_id: PYK22_00778
symbol: CDM64783.1
gene_biotype: protein_coding
description:
  ABC-type polysaccharide/polyol phosphate export systems, permease component; PFAM: ABC-2 type transporter; TIGRFAM: ABC-2 type transporter, NodJ family.


ensembl_gene_id: PYK22_00781
symbol: CDM64786.1
gene_biotype: protein_coding
description:
  NAD/NADP transhydrogenase beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.


ensembl_gene_id: PYK22_00783
symbol: CDM64788.1
gene_biotype: protein_coding
description:
  NAD/NADP transhydrogenase alpha subunit; PFAM: Alanine dehydrogenase/PNT, C-terminal domain; Alanine dehydrogenase/PNT, N-terminal domain; TIGRFAM: NAD(P) transhydrogenase, alpha subunit.


ensembl_gene_id: PYK22_00784
symbol: CDM64789.1
gene_biotype: protein_coding
description:
  Uncharacterized domain/protein associated with RNAses G and E; PFAM: Protein of unknown function (DUF402).


ensembl_gene_id: PYK22_00786
symbol: tal
gene_biotype: protein_coding
description:
  Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.


ensembl_gene_id: PYK22_00787
symbol: CDM64792.1
gene_biotype: protein_coding
description:
  2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase; PFAM: Domain of unknown function (DUF2437); Fumarylacetoacetate (FAA) hydrolase family.


ensembl_gene_id: PYK22_00789
symbol: hslU
gene_biotype: protein_coding
description:
  ATP-dependent protease HslVU, ATPase subunit; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.


ensembl_gene_id: PYK22_00790
symbol: hslV
gene_biotype: protein_coding
description:
  ATP dependent peptidase CodWX, CodW component; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.


ensembl_gene_id: PYK22_00793
symbol: CDM64798.1
gene_biotype: protein_coding
description:
  Mg-chelatase subunit ChlD; PFAM: von Willebrand factor type A domain; TIGRFAM: VWFA-related Acidobacterial domain.


ensembl_gene_id: PYK22_00798
symbol: ahcY
gene_biotype: protein_coding
description:
  Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.


ensembl_gene_id: PYK22_00799
symbol: metK
gene_biotype: protein_coding
description:
  Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.


ensembl_gene_id: PYK22_00801
symbol: CDM64806.1
gene_biotype: protein_coding
description:
  ParB-like partition protein; PFAM: ParB-like nuclease domain; KorB domain; TIGRFAM: ParB/RepB/Spo0J family partition protein; Belongs to the ParB family.


ensembl_gene_id: PYK22_00804
symbol: miaB
gene_biotype: protein_coding
description:
  tRNA-i(6)A37 thiotransferase enzyme MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.


ensembl_gene_id: PYK22_00806
symbol: CDM64811.1
gene_biotype: protein_coding
description:
  Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.


ensembl_gene_id: PYK22_00807
symbol: accA
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.


ensembl_gene_id: PYK22_00808
symbol: CDM64813.1
gene_biotype: protein_coding
description:
  PFAM: Bacterial DNA polymerase III alpha subunit; PHP domain; OB-fold nucleic acid binding domain; Helix-hairpin-helix motif; TIGRFAM: DNA-directed DNA polymerase III (polc).


ensembl_gene_id: PYK22_00810
symbol: CDM64815.1
gene_biotype: protein_coding
description:
  Phosphatidylserine synthase; PFAM: CDP-alcohol phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: PYK22_00811
symbol: psd
gene_biotype: protein_coding
description:
  Phosphatidylserine decarboxylase precursor-related protein; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).


ensembl_gene_id: PYK22_00813
symbol: CDM64818.1
gene_biotype: protein_coding
description:
  Ribosomal-protein-alanine acetyltransferase; Acetylates the N-terminal alanine of ribosomal protein S18.


ensembl_gene_id: PYK22_00815
symbol: galK
gene_biotype: protein_coding
description:
  Galactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily.


ensembl_gene_id: PYK22_00816
symbol: CDM64821.1
gene_biotype: protein_coding
description:
  PFAM: Galactose-1-phosphate uridyl transferase, C-terminal domain; Galactose-1-phosphate uridyl transferase, N-terminal domain; TIGRFAM: galactose-1-phosphate uridylyltransferase, family 1.


ensembl_gene_id: PYK22_00820
symbol: rbsA-3
gene_biotype: protein_coding
description:
  ABC-type sugar transport system, ATPase component; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family.


ensembl_gene_id: PYK22_00821
symbol: CDM64826.1
gene_biotype: protein_coding
description:
  Monosaccharide ABC transporter substrate-binding protein, CUT2 family; PFAM: Periplasmic binding protein domain.


ensembl_gene_id: PYK22_00823
symbol: CDM64828.1
gene_biotype: protein_coding
description:
  UDP-galactose 4-epimerase; PFAM: NAD dependent epimerase/dehydratase family; UDP-glucose 4-epimerase C-term subunit; TIGRFAM: UDP-glucose-4-epimerase GalE; Belongs to the NAD(P)-dependent epimerase/dehydratase family.


ensembl_gene_id: PYK22_00824
symbol: CDM64829.1
gene_biotype: protein_coding
description:
  PFAM: Galactokinase galactose-binding signature; GHMP kinases C terminal; GHMP kinases N terminal domain.


ensembl_gene_id: PYK22_00827
symbol: CDM64832.1
gene_biotype: protein_coding
description:
  Predicted beta-xylosidase; PFAM: Glycosyl hydrolases family 43; Belongs to the glycosyl hydrolase 43 family.


ensembl_gene_id: PYK22_00832
symbol: CDM64837.1
gene_biotype: protein_coding
description:
  Transcriptional regulator, LacI family; PFAM: Periplasmic binding protein domain; Bacterial regulatory proteins, lacI family.


ensembl_gene_id: PYK22_00836
symbol: CDM64841.1
gene_biotype: protein_coding
description:
  Outer membrane receptor protein; PFAM: TonB-dependent Receptor Plug Domain; Carboxypeptidase regulatory-like domain.


ensembl_gene_id: PYK22_00838
symbol: CDM64843.1
gene_biotype: protein_coding
description:
  ABC-type anion transport system, duplicated permease component; PFAM: Binding-protein-dependent transport system inner membrane component.


ensembl_gene_id: PYK22_00839
symbol: CDM64844.1
gene_biotype: protein_coding
description:
  ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component; PFAM: ABC transporter; C-terminal AAA-associated domain.


ensembl_gene_id: PYK22_00846
symbol: CDM64851.1
gene_biotype: protein_coding
description:
  Predicted PLP-dependent enzyme possibly involved in cell wall biogenesis; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase family.


ensembl_gene_id: PYK22_00853
symbol: xerC
gene_biotype: protein_coding
description:
  Site-specific recombinase XerD; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.


ensembl_gene_id: PYK22_00856
symbol: CDM64861.1
gene_biotype: protein_coding
description:
  PFAM: Elongation factor Tu domain 2; Elongation factor SelB, winged helix; Elongation factor Tu GTP binding domain; TIGRFAM: selenocysteine-specific elongation factor SelB; small GTP-binding protein domain; translation elongation factor TU.


ensembl_gene_id: PYK22_00867
symbol: CDM64872.1
gene_biotype: protein_coding
description:
  Zn-dependent hydrolase, glyoxylase; PFAM: Metallo-beta-lactamase superfamily; Rhodanese-like domain.


ensembl_gene_id: PYK22_00869
symbol: CDM64874.1
gene_biotype: protein_coding
description:
  Rhodanese-related sulfurtransferase; PFAM: Protein of unknown function (DUF2892); Rhodanese-like domain.


ensembl_gene_id: PYK22_00871
symbol: CDM64876.1
gene_biotype: protein_coding
description:
  Heme/copper-type cytochrome/quinol oxidase, subunit 1; PFAM: Domain of unknown function (DUF1858); NnrS protein; Cytochrome C and Quinol oxidase polypeptide I.


ensembl_gene_id: PYK22_00872
symbol: mutS
gene_biotype: protein_coding
description:
  DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.


ensembl_gene_id: PYK22_00874
symbol: CDM64879.1
gene_biotype: protein_coding
description:
  ABC-type dipeptide transport system, periplasmic component; PFAM: Bacterial extracellular solute-binding proteins, family 5 Middle.


ensembl_gene_id: PYK22_00886
symbol: CDM64891.1
gene_biotype: protein_coding
description:
  PFAM: Telomere recombination; TIGRFAM: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family; Belongs to the SUA5 family.


ensembl_gene_id: PYK22_00889
symbol: CDM64894.1
gene_biotype: protein_coding
description:
  PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phospho-acceptor) domain.


ensembl_gene_id: PYK22_00890
symbol: CDM64895.1
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease III; PFAM: Endonuclease/Exonuclease/phosphatase family; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III (xth).


ensembl_gene_id: PYK22_00892
symbol: CDM64897.1
gene_biotype: protein_coding
description:
  PFAM: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; TIGRFAM: UbiD family decarboxylase; Belongs to the UbiD family.


ensembl_gene_id: PYK22_00899
symbol: CDM64904.1
gene_biotype: protein_coding
description:
  RHS repeat-associated core domain; PFAM: D-alanyl-D-alanine carboxypeptidase; TIGRFAM: RHS repeat-associated core domain.


ensembl_gene_id: PYK22_00902
symbol: CDM64907.1
gene_biotype: protein_coding
description:
  PFAM: Flagellar basal body rod FlgEFG protein C-terminal; Flagella basal body rod protein; TIGRFAM: flagellar hook-basal body protein; flagellar basal-body rod protein FlgG, Gram-negative bacteria.


ensembl_gene_id: PYK22_00904
symbol: CDM64909.1
gene_biotype: protein_coding
description:
  Flagellar basal body L-ring protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.


ensembl_gene_id: PYK22_00905
symbol: flgI
gene_biotype: protein_coding
description:
  Flagellar basal-body P-ring protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.


ensembl_gene_id: PYK22_00909
symbol: flgK
gene_biotype: protein_coding
description:
  PFAM: Flagellar basal body rod FlgEFG protein C-terminal; Flagella basal body rod protein; TIGRFAM: flagellar hook-associated protein FlgK.


ensembl_gene_id: PYK22_00910
symbol: CDM64915.1
gene_biotype: protein_coding
description:
  Flagellar hook-associated protein 3; PFAM: Bacterial flagellin N-terminal helical region; Bacterial flagellin C-terminal helical region; TIGRFAM: flagellar hook-associated protein 3.


ensembl_gene_id: PYK22_00911
symbol: fliW
gene_biotype: protein_coding
description:
  Hypothetical protein; Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.


ensembl_gene_id: PYK22_00912
symbol: csrA
gene_biotype: protein_coding
description:
  Carbon storage regulator, CsrA; A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'- UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.


ensembl_gene_id: PYK22_00914
symbol: CDM64919.1
gene_biotype: protein_coding
description:
  Flagellin/flagellar hook associated protein; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.


ensembl_gene_id: PYK22_00916
symbol: CDM64921.1
gene_biotype: protein_coding
description:
  Flagellar capping protein; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.


ensembl_gene_id: PYK22_00921
symbol: CDM64926.1
gene_biotype: protein_coding
description:
  Histidine kinase,HAMP domain-containing protein,histidine kinase; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phospho-acceptor) domain.


ensembl_gene_id: PYK22_00923
symbol: CDM64928.1
gene_biotype: protein_coding
description:
  PFAM: Aldehyde dehydrogenase family; TIGRFAM: delta-1-pyrroline-5-carboxylate dehydrogenase, group 2, putative; Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: PYK22_00924
symbol: fmt
gene_biotype: protein_coding
description:
  methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.


ensembl_gene_id: PYK22_00925
symbol: CDM64930.1
gene_biotype: protein_coding
description:
  Ribosomal RNA small subunit methyltransferase RsmB; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.


ensembl_gene_id: PYK22_00927
symbol: CDM64932.1
gene_biotype: protein_coding
description:
  Ribulose-5-phosphate 3-epimerase; PFAM: Ribulose-phosphate 3 epimerase family; TIGRFAM: ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.


ensembl_gene_id: PYK22_00933
symbol: prs
gene_biotype: protein_coding
description:
  Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.


ensembl_gene_id: PYK22_00934
symbol: rplY
gene_biotype: protein_coding
description:
  Ribosomal protein L25, Ctc-form; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.


ensembl_gene_id: PYK22_00935
symbol: pth
gene_biotype: protein_coding
description:
  peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.


ensembl_gene_id: PYK22_00937
symbol: rpsR
gene_biotype: protein_coding
description:
  SSU ribosomal protein S18P; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.


ensembl_gene_id: PYK22_00939
symbol: CDM64943.1
gene_biotype: protein_coding
description:
  Primary replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily.


ensembl_gene_id: PYK22_00940
symbol: CDM64944.1
gene_biotype: protein_coding
description:
  Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.


ensembl_gene_id: PYK22_00942
symbol: CDM64946.1
gene_biotype: protein_coding
description:
  Uncharacterized anaerobic dehydrogenase; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; Molybdopterin oxidoreductase Fe4S4 domain; TIGRFAM: formate dehydrogenase, alpha subunit, archaeal-type; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: PYK22_00944
symbol: CDM64948.1
gene_biotype: protein_coding
description:
  Ferredoxin subunit of nitrite reductase and ring-hydroxylating dioxygenase; PFAM: Rieske [2Fe-2S] domain.


ensembl_gene_id: PYK22_00949
symbol: frr
gene_biotype: protein_coding
description:
  Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.


ensembl_gene_id: PYK22_00951
symbol: tsf
gene_biotype: protein_coding
description:
  Translation elongation factor Ts (EF-Ts); Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.


ensembl_gene_id: PYK22_00952
symbol: rpsB
gene_biotype: protein_coding
description:
  PFAM: Ribosomal protein S2; TIGRFAM: ribosomal protein S2, bacterial type; Belongs to the universal ribosomal protein uS2 family.


ensembl_gene_id: PYK22_00954
symbol: rplM
gene_biotype: protein_coding
description:
  LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.


ensembl_gene_id: PYK22_00956
symbol: CDM64960.1
gene_biotype: protein_coding
description:
  ABC-type transport system, involved in lipoprotein release, permease component; PFAM: MacB-like periplasmic core domain; FtsX-like permease family.


ensembl_gene_id: PYK22_00962
symbol: CDM64966.1
gene_biotype: protein_coding
description:
  Iron-regulated ABC transporter membrane component SufB; PFAM: Uncharacterized protein family (UPF0051); TIGRFAM: FeS assembly protein SufB.


ensembl_gene_id: PYK22_00964
symbol: CDM64968.1
gene_biotype: protein_coding
description:
  FeS assembly protein SufD; PFAM: Uncharacterized protein family (UPF0051); TIGRFAM: FeS assembly protein SufD.


ensembl_gene_id: PYK22_00965
symbol: CDM64969.1
gene_biotype: protein_coding
description:
  Cysteine desulfurase-like protein, SufS subfamily; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.


ensembl_gene_id: PYK22_00967
symbol: menC
gene_biotype: protein_coding
description:
  O-succinylbenzoate synthase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB).


ensembl_gene_id: PYK22_00968
symbol: CDM64972.1
gene_biotype: protein_coding
description:
  Acetylornithine deacetylase/succinyldiaminopimelate desuccinylase-like deacylase; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain.


ensembl_gene_id: PYK22_00969
symbol: CDM64973.1
gene_biotype: protein_coding
description:
  Gamma-glutamyltransferase 1; PFAM: Gamma-glutamyltranspeptidase; TIGRFAM: gamma-glutamyltranspeptidase.


ensembl_gene_id: PYK22_00972
symbol: thiE
gene_biotype: protein_coding
description:
  Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.


ensembl_gene_id: PYK22_00981
symbol: CDM64985.1
gene_biotype: protein_coding
description:
  PFAM: Cation efflux family; TIGRFAM: cation diffusion facilitator family transporter; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.


ensembl_gene_id: PYK22_00983
symbol: CDM64987.1
gene_biotype: protein_coding
description:
  Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


ensembl_gene_id: PYK22_00984
symbol: CDM64988.1
gene_biotype: protein_coding
description:
  Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.


ensembl_gene_id: PYK22_00985
symbol: pdhA
gene_biotype: protein_coding
description:
  Pyruvate dehydrogenase E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


ensembl_gene_id: PYK22_00989
symbol: CDM64993.1
gene_biotype: protein_coding
description:
  Highly conserved protein containing a thioredoxin domain; PFAM: N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase); Protein of unknown function, DUF255.


ensembl_gene_id: PYK22_00992
symbol: CDM64996.1
gene_biotype: protein_coding
description:
  Outer membrane transport energization protein ExbB (TC 2.C.1.1.1); PFAM: MotA/TolQ/ExbB proton channel family.


ensembl_gene_id: PYK22_00996
symbol: CDM65000.1
gene_biotype: protein_coding
description:
  (p)ppGpp synthetase, RelA/SpoT family; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.


ensembl_gene_id: PYK22_00998
symbol: rpmB
gene_biotype: protein_coding
description:
  LSU ribosomal protein L28P; PFAM: Ribosomal L28 family; TIGRFAM: ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family.


ensembl_gene_id: PYK22_01002
symbol: thrS
gene_biotype: protein_coding
description:
  threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).


ensembl_gene_id: PYK22_01003
symbol: infC
gene_biotype: protein_coding
description:
  Bacterial translation initiation factor 3 (bIF-3); IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.


ensembl_gene_id: PYK22_01004
symbol: rpmI
gene_biotype: protein_coding
description:
  PFAM: Ribosomal protein L35; TIGRFAM: ribosomal protein L35; Belongs to the bacterial ribosomal protein bL35 family.


ensembl_gene_id: PYK22_01005
symbol: rplT
gene_biotype: protein_coding
description:
  LSU ribosomal protein L20P; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.


ensembl_gene_id: PYK22_01006
symbol: pheS
gene_biotype: protein_coding
description:
  phenylalanyl-tRNA synthetase, alpha subunit; PFAM: tRNA synthetases class II core domain (F); Aminoacyl tRNA synthetase class II, N-terminal domain; TIGRFAM: phenylalanyl-tRNA synthetase, alpha subunit; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.


ensembl_gene_id: PYK22_01007
symbol: pheT
gene_biotype: protein_coding
description:
  phenylalanyl-tRNA synthetase beta subunit; PFAM: tRNA synthetase B5 domain; Ferredoxin-fold anticodon binding domain; B3/4 domain; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit, non-spirochete bacterial; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.


ensembl_gene_id: PYK22_01009
symbol: CDM65012.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.


ensembl_gene_id: PYK22_01016
symbol: CDM65019.1
gene_biotype: protein_coding
description:
  PAS domain S-box; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phospho-acceptor) domain; PAS domain; TIGRFAM: PAS domain S-box.


ensembl_gene_id: PYK22_01018
symbol: CDM65021.1
gene_biotype: protein_coding
description:
  Pseudouridine synthase, RluA family; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.


ensembl_gene_id: PYK22_01022
symbol: CDM65025.1
gene_biotype: protein_coding
description:
  Cyclic pyranopterin monophosphate synthase subunit MoaC; PFAM: MoaC family; TIGRFAM: molybdenum cofactor biosynthesis protein MoaC.


ensembl_gene_id: PYK22_01024
symbol: CDM65027.1
gene_biotype: protein_coding
description:
  Carbohydrate ABC transporter substrate-binding protein, CUT1 family; PFAM: Bacterial extracellular solute-binding protein.


ensembl_gene_id: PYK22_01033
symbol: CDM65036.1
gene_biotype: protein_coding
description:
  2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase; PFAM: Fumarylacetoacetate (FAA) hydrolase family.


ensembl_gene_id: PYK22_01040
symbol: CDM65043.1
gene_biotype: protein_coding
description:
  Hypothetical protein; PFAM: 4Fe-4S dicluster domain; Uncharacterised ACR, YkgG family COG1556; TIGRFAM: iron-sulfur cluster-binding protein.


ensembl_gene_id: PYK22_01043
symbol: CDM65045.1
gene_biotype: protein_coding
description:
  PFAM: Type IV pilin N-term methylation site GFxxxE; TIGRFAM: prepilin-type N-terminal cleavage/methylation domain.


ensembl_gene_id: PYK22_01046
symbol: CDM65048.1
gene_biotype: protein_coding
description:
  Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.


ensembl_gene_id: PYK22_01047
symbol: hemH
gene_biotype: protein_coding
description:
  Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.


ensembl_gene_id: PYK22_01048
symbol: hemE
gene_biotype: protein_coding
description:
  Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.


ensembl_gene_id: PYK22_01051
symbol: CDM65053.1
gene_biotype: protein_coding
description:
  PFAM: Molybdopterin-binding domain of aldehyde dehydrogenase; Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; TIGRFAM: carbon-monoxide dehydrogenase, large subunit.


ensembl_gene_id: PYK22_01052
symbol: CDM65054.1
gene_biotype: protein_coding
description:
  Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS-like protein; PFAM: 2Fe-2S iron-sulfur cluster binding domain; [2Fe-2S] binding domain.


ensembl_gene_id: PYK22_01059
symbol: CDM65061.1
gene_biotype: protein_coding
description:
  RRM domain-containing RNA-binding protein; PFAM: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain).


ensembl_gene_id: PYK22_01062
symbol: mdh
gene_biotype: protein_coding
description:
  Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.


ensembl_gene_id: PYK22_01063
symbol: fdhD
gene_biotype: protein_coding
description:
  Formate dehydrogenase family accessory protein FdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.


ensembl_gene_id: PYK22_01064
symbol: CDM65066.1
gene_biotype: protein_coding
description:
  Molybdopterin-dependent oxidoreductase alpha subunit; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; TIGRFAM: oxidoreductase alpha (molybdopterin) subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: PYK22_01065
symbol: CDM65067.1
gene_biotype: protein_coding
description:
  Succinate dehydrogenase subunit B; PFAM: 2Fe-2S iron-sulfur cluster binding domain; 4Fe-4S dicluster domain; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein.


ensembl_gene_id: PYK22_01066
symbol: CDM65068.1
gene_biotype: protein_coding
description:
  Succinate dehydrogenase subunit A; PFAM: FAD binding domain; Fumarate reductase flavoprotein C-term; TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit, Bacillus subtilis subgroup.


ensembl_gene_id: PYK22_01067
symbol: CDM65069.1
gene_biotype: protein_coding
description:
  PFAM: Succinate dehydrogenase/Fumarate reductase transmembrane subunit; TIGRFAM: succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family.


ensembl_gene_id: PYK22_01074
symbol: sat
gene_biotype: protein_coding
description:
  Sulfate adenylyltransferase; PFAM: PUA-like domain; ATP-sulfurylase; TIGRFAM: ATP sulphurylase; Belongs to the sulfate adenylyltransferase family.


ensembl_gene_id: PYK22_01075
symbol: CDM65077.1
gene_biotype: protein_coding
description:
  uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family.


ensembl_gene_id: PYK22_01076
symbol: CDM65078.1
gene_biotype: protein_coding
description:
  ABC-type polysaccharide/polyol phosphate export systems, permease component; PFAM: ABC-2 type transporter.


ensembl_gene_id: PYK22_01077
symbol: CDM65079.1
gene_biotype: protein_coding
description:
  ABC-type polysaccharide/polyol phosphate transport system, ATPase component; PFAM: ABC transporter; Wzt C-terminal domain.


ensembl_gene_id: PYK22_01081
symbol: gmd
gene_biotype: protein_coding
description:
  GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose.


ensembl_gene_id: PYK22_01082
symbol: fcl
gene_biotype: protein_coding
description:
  Nucleoside-diphosphate-sugar epimerase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.


ensembl_gene_id: PYK22_01095
symbol: CDM65097.1
gene_biotype: protein_coding
description:
  Asparagine synthase, glutamine-hydrolyzing; PFAM: Glutamine amidotransferase domain; Asparagine synthase; TIGRFAM: asparagine synthase (glutamine-hydrolyzing).


ensembl_gene_id: PYK22_01098
symbol: CDM65100.1
gene_biotype: protein_coding
description:
  PFAM: Nucleotidyl transferase; TIGRFAM: glucose-1-phosphate thymidylylransferase, long form; glucose-1-phosphate thymidylyltransferase, short form.


ensembl_gene_id: PYK22_01100
symbol: corA
gene_biotype: protein_coding
description:
  Magnesium Mg(2+) and cobalt Co(2+) transport protein CorA; Mediates influx of magnesium ions. Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.


ensembl_gene_id: PYK22_01102
symbol: CDM65104.1
gene_biotype: protein_coding
description:
  PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; ACT domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; TIGRFAM: D-3-phosphoglycerate dehydrogenase.


ensembl_gene_id: PYK22_01103
symbol: CDM65105.1
gene_biotype: protein_coding
description:
  ABC-type uncharacterized transport system, ATPase component; PFAM: ABC transporter; Domain of unknown function (DUF4162).


ensembl_gene_id: PYK22_01107
symbol: groL
gene_biotype: protein_coding
description:
  Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.


ensembl_gene_id: PYK22_01108
symbol: groS
gene_biotype: protein_coding
description:
  Co-chaperonin GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.


ensembl_gene_id: PYK22_01114
symbol: uvrB
gene_biotype: protein_coding
description:
  Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate  [...]


ensembl_gene_id: PYK22_01115
symbol: aroC
gene_biotype: protein_coding
description:
  Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.


ensembl_gene_id: PYK22_01116
symbol: def
gene_biotype: protein_coding
description:
  Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.


ensembl_gene_id: PYK22_01119
symbol: CDM65121.1
gene_biotype: protein_coding
description:
  PFAM: Glutamine synthetase, catalytic domain; Glutamine synthetase, beta-Grasp domain; TIGRFAM: glutamine synthetase, type I.


ensembl_gene_id: PYK22_01125
symbol: CDM65127.1
gene_biotype: protein_coding
description:
  Alpha-glucuronidase; PFAM: Glycosyl hydrolase family 67 C-terminus; Glycosyl hydrolase family 67 middle domain; Glycosyl hydrolase family 67 N-terminus; Belongs to the glycosyl hydrolase 67 family.


ensembl_gene_id: PYK22_01126
symbol: CDM65128.1
gene_biotype: protein_coding
description:
  Enolase superfamily enzyme related to L-alanine-DL-glutamate epimerase; PFAM: Mandelate racemase / muconate lactonizing enzyme, C-terminal domain; Enolase C-terminal domain-like; Mandelate racemase / muconate lactonizing enzyme, N-terminal domain.


ensembl_gene_id: PYK22_01129
symbol: CDM65131.1
gene_biotype: protein_coding
description:
  Glycoside/pentoside/hexuronide transporter; PFAM: MFS/sugar transport protein; TIGRFAM: sugar (Glycoside-Pentoside-Hexuronide) transporter.


ensembl_gene_id: PYK22_01131
symbol: CDM65133.1
gene_biotype: protein_coding
description:
  PFAM: Glycosyl hydrolase family 3 C-terminal domain; Glycosyl hydrolase family 3 N terminal domain; PA14 domain; Fibronectin type III-like domain.


ensembl_gene_id: PYK22_01137
symbol: CDM65139.1
gene_biotype: protein_coding
description:
  Glutamine synthetase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transducti [...]


ensembl_gene_id: PYK22_01139
symbol: CDM65141.1
gene_biotype: protein_coding
description:
  PFAM: RHS Repeat; Subtilase family; TIGRFAM: RHS repeat-associated core domain; YD repeat (two copies).


ensembl_gene_id: PYK22_01151
symbol: CDM65153.1
gene_biotype: protein_coding
description:
  4-hydroxybenzoyl-CoA reductase beta subunit; PFAM: FAD binding domain in molybdopterin dehydrogenase; CO dehydrogenase flavoprotein C-terminal domain; TIGRFAM: 4-hydroxybenzoyl-CoA reductase, beta subunit.


ensembl_gene_id: PYK22_01153
symbol: CDM65155.1
gene_biotype: protein_coding
description:
  4-hydroxybenzoyl-CoA reductase, alpha subunit; PFAM: Molybdopterin-binding domain of aldehyde dehydrogenase; Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; TIGRFAM: 4-hydroxybenzoyl-CoA reductase, alpha subunit.


ensembl_gene_id: PYK22_01163
symbol: CDM65165.1
gene_biotype: protein_coding
description:
  Aromatic ring hydroxylase; PFAM: 4-hydroxyphenylacetate 3-hydroxylase N terminal; 4-hydroxyphenylacetate 3-hydroxylase C terminal; TIGRFAM: 4-hydroxyphenylacetate 3-monooxygenase, oxygenase component.


ensembl_gene_id: PYK22_01166
symbol: CDM65168.1
gene_biotype: protein_coding
description:
  CBM6-containing protein; PFAM: Right handed beta helix region; Carbohydrate binding module (family 6).


ensembl_gene_id: PYK22_01170
symbol: CDM65172.1
gene_biotype: protein_coding
description:
  Capsular exopolysaccharide biosynthesis protein; PFAM: AAA domain; Chain length determinant protein; G-rich domain on putative tyrosine kinase; TIGRFAM: capsular exopolysaccharide family.


ensembl_gene_id: PYK22_01177
symbol: CDM65179.1
gene_biotype: protein_coding
description:
  PFAM: UDP-N-acetylglucosamine 2-epimerase; TIGRFAM: UDP-N-acetyl-D-glucosamine 2-epimerase, UDP-hydrolysing.


ensembl_gene_id: PYK22_01179
symbol: CDM65181.1
gene_biotype: protein_coding
description:
  2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1, 4-benzoquinol methylase; PFAM: Methyltransferase domain.


ensembl_gene_id: PYK22_01193
symbol: CDM65195.1
gene_biotype: protein_coding
description:
  Predicted dehydrogenase; PFAM: NAD dependent epimerase/dehydratase family; Oxidoreductase family, NAD-binding Rossmann fold.


ensembl_gene_id: PYK22_01199
symbol: CDM65201.1
gene_biotype: protein_coding
description:
  Transposase, IS605 OrfB family, central region; PFAM: Helix-turn-helix domain; Putative transposase DNA-binding domain; Probable transposase; TIGRFAM: transposase, IS605 OrfB family, central region.


ensembl_gene_id: PYK22_01206
symbol: CDM65208.1
gene_biotype: protein_coding
description:
  Glycosyl transferase possibly involved in lipopolysaccharide synthesis; PFAM: Bacterial sugar transferase.


ensembl_gene_id: PYK22_01207
symbol: CDM65209.1
gene_biotype: protein_coding
description:
  Predicted nucleoside-diphosphate sugar epimerase; PFAM: CoA-binding domain; Polysaccharide biosynthesis protein.


ensembl_gene_id: PYK22_01214
symbol: CDM65216.1
gene_biotype: protein_coding
description:
  Short-chain alcohol dehydrogenase; PFAM: short chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: PYK22_01217
symbol: CDM65219.1
gene_biotype: protein_coding
description:
  PFAM: Putative zinc binding domain; Methyltransferase domain; C-methyltransferase C-terminal domain.


ensembl_gene_id: PYK22_01225
symbol: CDM65227.1
gene_biotype: protein_coding
description:
  Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; PFAM: Helix-turn-helix domain.


ensembl_gene_id: PYK22_01226
symbol: CDM65228.1
gene_biotype: protein_coding
description:
  Two component transcriptional regulator, LuxR family; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family; TIGRFAM: RNA polymerase sigma factor, sigma-70 family.


ensembl_gene_id: PYK22_01227
symbol: CDM65229.1
gene_biotype: protein_coding
description:
  Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains; PFAM: Bacterial regulatory protein, Fis family; Sigma-54 interaction domain.


ensembl_gene_id: PYK22_01229
symbol: CDM65231.1
gene_biotype: protein_coding
description:
  dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.


ensembl_gene_id: PYK22_01235
symbol: CDM65237.1
gene_biotype: protein_coding
description:
  Hypothetical protein; PFAM: Phenylacetic acid catabolic protein; TIGRFAM: phenylacetate-CoA oxygenase, PaaI subunit.


ensembl_gene_id: PYK22_01236
symbol: CDM65238.1
gene_biotype: protein_coding
description:
  Transcriptional regulator, TetR family; PFAM: Bacterial transcriptional repressor; Bacterial regulatory proteins, tetR family.


ensembl_gene_id: PYK22_01237
symbol: ppc
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate carboxylase, type 1; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family.


ensembl_gene_id: PYK22_01238
symbol: menG
gene_biotype: protein_coding
description:
  Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).


ensembl_gene_id: PYK22_01247
symbol: coaD
gene_biotype: protein_coding
description:
  Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.


ensembl_gene_id: PYK22_01248
symbol: CDM65250.1
gene_biotype: protein_coding
description:
  Bacterial cell division membrane protein; PFAM: Cell cycle protein; TIGRFAM: rod shape-determining protein RodA; Belongs to the SEDS family.


ensembl_gene_id: PYK22_01249
symbol: CDM65251.1
gene_biotype: protein_coding
description:
  Peptidoglycan glycosyltransferase; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain; TIGRFAM: penicillin-binding protein 2.


ensembl_gene_id: PYK22_01257
symbol: CDM65259.1
gene_biotype: protein_coding
description:
  Putative hydrolase, CocE/NonD family; PFAM: X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain; X-Pro dipeptidyl-peptidase (S15 family); TIGRFAM: putative hydrolase, CocE/NonD family.


ensembl_gene_id: PYK22_01263
symbol: CDM65265.1
gene_biotype: protein_coding
description:
  DNA-binding protein with winged-HTH domain; PFAM: Transcriptional regulatory protein, C terminal; Tetratricopeptide repeat; TPR repeat.


ensembl_gene_id: PYK22_01272
symbol: lpxC
gene_biotype: protein_coding
description:
  UDP-3-O-(3-hydroxymyristoyl) N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family.


ensembl_gene_id: PYK22_01273
symbol: polA
gene_biotype: protein_coding
description:
  DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.


ensembl_gene_id: PYK22_01275
symbol: folD
gene_biotype: protein_coding
description:
  5,10-methylene-tetrahydrofolate dehydrogenase/methenyl tetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.


ensembl_gene_id: PYK22_01276
symbol: coaE
gene_biotype: protein_coding
description:
  dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.


ensembl_gene_id: PYK22_01277
symbol: CDM65279.1
gene_biotype: protein_coding
description:
  ABC-type oligopeptide transport system, periplasmic component; PFAM: Bacterial extracellular solute-binding proteins, family 5 Middle.


ensembl_gene_id: PYK22_01278
symbol: CDM65280.1
gene_biotype: protein_coding
description:
  ABC-type dipeptide/oligopeptide/nickel transport system, permease component; PFAM: Binding-protein-dependent transport system inner membrane component.


ensembl_gene_id: PYK22_01279
symbol: CDM65281.1
gene_biotype: protein_coding
description:
  PFAM: Binding-protein-dependent transport system inner membrane component; N-terminal TM domain of oligopeptide transport permease C.


ensembl_gene_id: PYK22_01280
symbol: CDM65282.1
gene_biotype: protein_coding
description:
  PFAM: ABC transporter; Oligopeptide/dipeptide transporter, C-terminal region; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Belongs to the ABC transporter superfamily.


ensembl_gene_id: PYK22_01282
symbol: CDM65284.1
gene_biotype: protein_coding
description:
  Diguanylate cyclase with GAF sensor; PFAM: GGDEF domain; GAF domain; Sensory domain found in PocR; TIGRFAM: diguanylate cyclase (GGDEF) domain.


ensembl_gene_id: PYK22_01287
symbol: ybeY
gene_biotype: protein_coding
description:
  Probable rRNA maturation factor YbeY; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.


ensembl_gene_id: PYK22_01288
symbol: CDM65290.1
gene_biotype: protein_coding
description:
  CBS domain-containing protein; PFAM: CBS domain; Domain of unknown function DUF21; Transporter associated domain.


ensembl_gene_id: PYK22_01293
symbol: CDM65295.1
gene_biotype: protein_coding
description:
  Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.


ensembl_gene_id: PYK22_01295
symbol: CDM65297.1
gene_biotype: protein_coding
description:
  Conserved protein of unknown function BmrU; PFAM: Diacylglycerol kinase catalytic domain; TIGRFAM: lipid kinase, YegS/Rv2252/BmrU family.


ensembl_gene_id: PYK22_01297
symbol: CDM65299.1
gene_biotype: protein_coding
description:
  arginyl-tRNA synthetase; PFAM: DALR anticodon binding domain; Arginyl tRNA synthetase N terminal domain; tRNA synthetases class I (R); Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: PYK22_01298
symbol: CDM65300.1
gene_biotype: protein_coding
description:
  PFAM: Binding-protein-dependent transport system inner membrane component; Bacterial extracellular solute-binding proteins, family 3; TIGRFAM: amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family.


ensembl_gene_id: PYK22_01301
symbol: CDM65303.1
gene_biotype: protein_coding
description:
  TIGR00299 family protein; PFAM: Protein of unknown function DUF111; TIGRFAM: TIGR00299 family protein; Belongs to the LarC family.


ensembl_gene_id: PYK22_01304
symbol: metG
gene_biotype: protein_coding
description:
  methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.


ensembl_gene_id: PYK22_01306
symbol: CDM65308.1
gene_biotype: protein_coding
description:
  Geranylgeranyl pyrophosphate synthase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.


ensembl_gene_id: PYK22_01308
symbol: CDM65310.1
gene_biotype: protein_coding
description:
  Endo-beta-mannanase; PFAM: Sugar-binding cellulase-like; Belongs to the glycosyl hydrolase 5 (cellulase A) family.


ensembl_gene_id: PYK22_01309
symbol: CDM65311.1
gene_biotype: protein_coding
description:
  ABC-type sugar transport system, periplasmic component; PFAM: Bacterial extracellular solute-binding protein.


ensembl_gene_id: PYK22_01312
symbol: CDM65314.1
gene_biotype: protein_coding
description:
  Monoamine oxidase; PFAM: Flavin containing amine oxidoreductase; NAD(P)-binding Rossmann-like domain.


ensembl_gene_id: PYK22_01315
symbol: CDM65317.1
gene_biotype: protein_coding
description:
  N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA; PFAM: Glycosyltransferase Family 4; Glycosyl transferases group 1; TIGRFAM: N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA.


ensembl_gene_id: PYK22_01324
symbol: CDM65326.1
gene_biotype: protein_coding
description:
  SAM-dependent methyltransferase, tRNA(uracil-5)-methyltransferase; PFAM: tRNA (Uracil-5-)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.


ensembl_gene_id: PYK22_01325
symbol: deoB
gene_biotype: protein_coding
description:
  Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family.


ensembl_gene_id: PYK22_01326
symbol: mutM
gene_biotype: protein_coding
description:
  DNA-(apurinic or apyrimidinic site) lyase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.


ensembl_gene_id: PYK22_01328
symbol: CDM65330.1
gene_biotype: protein_coding
description:
  Nucleotidyltransferase; PFAM: Nucleotidyl transferase; Bacterial transferase hexapeptide (six repeats).


ensembl_gene_id: PYK22_01333
symbol: xerC-2
gene_biotype: protein_coding
description:
  Tyrosine recombinase XerD subunit; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.


ensembl_gene_id: PYK22_01334
symbol: CDM65336.1
gene_biotype: protein_coding
description:
  Transcriptional regulator, TraR/DksA family; PFAM: Prokaryotic dksA/traR C4-type zinc finger; TIGRFAM: RNA polymerase-binding protein DksA.


ensembl_gene_id: PYK22_01338
symbol: asnS
gene_biotype: protein_coding
description:
  PFAM: tRNA synthetases class II (D, K and N); OB-fold nucleic acid binding domain; TIGRFAM: asparaginyl-tRNA synthetase.


ensembl_gene_id: PYK22_01342
symbol: ddl
gene_biotype: protein_coding
description:
  D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.


ensembl_gene_id: PYK22_01351
symbol: CDM65353.1
gene_biotype: protein_coding
description:
  Membrane protein involved in the export of O-antigen and teichoic acid; PFAM: Polysaccharide biosynthesis protein.


ensembl_gene_id: PYK22_01356
symbol: CDM65358.1
gene_biotype: protein_coding
description:
  Uncharacterized peroxidase-related enzyme; PFAM: Carboxymuconolactone decarboxylase family; TIGRFAM: uncharacterized peroxidase-related enzyme; alkylhydroperoxidase AhpD family core domain.


ensembl_gene_id: PYK22_01357
symbol: CDM65359.1
gene_biotype: protein_coding
description:
  DNA segregation ATPase, FtsK/SpoIIIE family; PFAM: Ftsk gamma domain; FtsK/SpoIIIE family; Domain of unknown function (DUF4117).


ensembl_gene_id: PYK22_01358
symbol: prfB
gene_biotype: protein_coding
description:
  Bacterial peptide chain release factor 2 (bRF-2); Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.


ensembl_gene_id: PYK22_01359
symbol: lnt
gene_biotype: protein_coding
description:
  Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily.


ensembl_gene_id: PYK22_01364
symbol: asd
gene_biotype: protein_coding
description:
  Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.


ensembl_gene_id: PYK22_01365
symbol: CDM65366.1
gene_biotype: protein_coding
description:
  2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; PFAM: Hexapeptide repeat of succinyl-transferase; Bacterial transferase hexapeptide (six repeats); Tetrahydrodipicolinate N-succinyltransferase N-terminal; TIGRFAM: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family.


ensembl_gene_id: PYK22_01366
symbol: dapA
gene_biotype: protein_coding
description:
  Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).


ensembl_gene_id: PYK22_01367
symbol: CDM65368.1
gene_biotype: protein_coding
description:
  PFAM: Dihydrodipicolinate reductase, N-terminus; Dihydrodipicolinate reductase, C-terminus; TIGRFAM: dihydrodipicolinate reductase; Belongs to the DapB family.


ensembl_gene_id: PYK22_01369
symbol: CDM65370.1
gene_biotype: protein_coding
description:
  PFAM: Amino acid kinase family; TIGRFAM: aspartate kinase, monofunctional class; aspartate kinase; Belongs to the aspartokinase family.


ensembl_gene_id: PYK22_01373
symbol: CDM65374.1
gene_biotype: protein_coding
description:
  D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4); PFAM: D-Ala-D-Ala carboxypeptidase 3 (S13) family.


ensembl_gene_id: PYK22_01378
symbol: CDM65379.1
gene_biotype: protein_coding
description:
  Conserved repeat protein; PFAM: Concanavalin A-like lectin/glucanases superfamily; Domain of unknown function DUF11; TIGRFAM: conserved repeat domain.


ensembl_gene_id: PYK22_01397
symbol: CDM65398.1
gene_biotype: protein_coding
description:
  PFAM: C-5 cytosine-specific DNA methylase; TIGRFAM: DNA-methyltransferase (dcm); Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.


ensembl_gene_id: PYK22_01398
symbol: CDM65399.1
gene_biotype: protein_coding
description:
  T/G mismatch-specific endonuclease; May nick specific sequences that contain T:G mispairs resulting from m5C-deamination.


ensembl_gene_id: PYK22_01408
symbol: CDM65409.1
gene_biotype: protein_coding
description:
  PFAM: Bacterial extracellular solute-binding protein; TIGRFAM: molybdenum ABC transporter, periplasmic molybdate-binding protein.


ensembl_gene_id: PYK22_01409
symbol: CDM65410.1
gene_biotype: protein_coding
description:
  Molybdate ABC transporter, permease protein; Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: PYK22_01413
symbol: CDM65414.1
gene_biotype: protein_coding
description:
  Transposase, IS605 OrfB family, central region; PFAM: Putative transposase DNA-binding domain; Probable transposase; TIGRFAM: transposase, IS605 OrfB family, central region.


ensembl_gene_id: PYK22_01442
symbol: CDM65441.1
gene_biotype: protein_coding
description:
  Pyrophosphate-dependent phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family.


ensembl_gene_id: PYK22_01445
symbol: murQ
gene_biotype: protein_coding
description:
  N-acetylmuramic acid 6-phosphate etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate.


ensembl_gene_id: PYK22_01449
symbol: ispD
gene_biotype: protein_coding
description:
  2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).


ensembl_gene_id: PYK22_01454
symbol: CDM65453.1
gene_biotype: protein_coding
description:
  PEP-CTERM putative exosortase interaction domain-containing protein; PFAM: PEP-CTERM motif; TIGRFAM: PEP-CTERM protein-sorting domain; MYXO-CTERM domain.


ensembl_gene_id: PYK22_01460
symbol: CDM65459.1
gene_biotype: protein_coding
description:
  PFAM: Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.


ensembl_gene_id: PYK22_01462
symbol: CDM65461.1
gene_biotype: protein_coding
description:
  PFAM: BNR/Asp-box repeat; Putative peptidoglycan binding domain; Photosynthesis system II assembly factor YCF48.


ensembl_gene_id: PYK22_01463
symbol: CDM65462.1
gene_biotype: protein_coding
description:
  PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Domain of unknown function (DUF4118); His Kinase A (phospho-acceptor) domain.


ensembl_gene_id: PYK22_01467
symbol: CDM65466.1
gene_biotype: protein_coding
description:
  PFAM: F subunit of K+-transporting ATPase (Potass_KdpF); TIGRFAM: K+-transporting ATPase, KdpF subunit.


ensembl_gene_id: PYK22_01468
symbol: kdpA
gene_biotype: protein_coding
description:
  K+-transporting ATPase, KdpA; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane.


ensembl_gene_id: PYK22_01469
symbol: kdpB
gene_biotype: protein_coding
description:
  K+-transporting ATPase, B subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.


ensembl_gene_id: PYK22_01470
symbol: kdpC
gene_biotype: protein_coding
description:
  K+-transporting ATPase, C subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.


ensembl_gene_id: PYK22_01473
symbol: CDM65472.1
gene_biotype: protein_coding
description:
  PFAM: Major Facilitator Superfamily; TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; Multidrug resistance protein.


ensembl_gene_id: PYK22_01479
symbol: CDM65478.1
gene_biotype: protein_coding
description:
  Bacterial nucleoid DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.


ensembl_gene_id: PYK22_01482
symbol: CDM65481.1
gene_biotype: protein_coding
description:
  PLP-dependent enzyme, glutamate decarboxylase; PFAM: Pyridoxal-dependent decarboxylase conserved domain.


ensembl_gene_id: PYK22_01484
symbol: CDM65483.1
gene_biotype: protein_coding
description:
  Amino acid/polyamine/organocation transporter, APC superfamily (TC 2.A.3); PFAM: Amino acid permease; TIGRFAM: amino acid transporter.


ensembl_gene_id: PYK22_01487
symbol: argG
gene_biotype: protein_coding
description:
  PFAM: Arginosuccinate synthase; TIGRFAM: argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.


ensembl_gene_id: PYK22_01489
symbol: argC
gene_biotype: protein_coding
description:
  N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.


ensembl_gene_id: PYK22_01490
symbol: CDM65489.1
gene_biotype: protein_coding
description:
  PFAM: Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: PYK22_01491
symbol: CDM65490.1
gene_biotype: protein_coding
description:
  PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFAM: ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily.


ensembl_gene_id: PYK22_01492
symbol: argB
gene_biotype: protein_coding
description:
  N-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.


ensembl_gene_id: PYK22_01495
symbol: apt
gene_biotype: protein_coding
description:
  Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.


ensembl_gene_id: PYK22_01505
symbol: ispF
gene_biotype: protein_coding
description:
  2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).


ensembl_gene_id: PYK22_01506
symbol: CDM65503.1
gene_biotype: protein_coding
description:
  PFAM: Pyrimidine nucleoside phosphorylase C-terminal domain; Glycosyl transferase family, a/b domain; Glycosyl transferase family, helical bundle domain; TIGRFAM: thymidine phosphorylase; pyrimidine-nucleoside phosphorylase.


ensembl_gene_id: PYK22_01507
symbol: CDM65504.1
gene_biotype: protein_coding
description:
  PFAM: Na+ dependent nucleoside transporter C-terminus; Na+ dependent nucleoside transporter N-terminus; Nucleoside recognition; Photosynthesis system II assembly factor YCF48; TIGRFAM: nucleoside transporter; Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.


ensembl_gene_id: PYK22_01508
symbol: CDM65505.1
gene_biotype: protein_coding
description:
  Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.


ensembl_gene_id: PYK22_01510
symbol: CDM65507.1
gene_biotype: protein_coding
description:
  Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.


ensembl_gene_id: PYK22_01511
symbol: mtaD
gene_biotype: protein_coding
description:
  Cytosine deaminase-like metal-dependent hydrolase; Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.


ensembl_gene_id: PYK22_01513
symbol: CDM65510.1
gene_biotype: protein_coding
description:
  DNA polymerase LigD, polymerase domain; PFAM: Eukaryotic and archaeal DNA primase small subunit; TIGRFAM: DNA ligase D; DNA polymerase LigD, polymerase domain.


ensembl_gene_id: PYK22_01515
symbol: CDM65512.1
gene_biotype: protein_coding
description:
  CRISPR-associated helicase Cas3, subtype Dpsyc; PFAM: Helicase conserved C-terminal domain; Type III restriction enzyme, res subunit; TIGRFAM: CRISPR-associated helicase Cas3, subtype Dpsyc.


ensembl_gene_id: PYK22_01517
symbol: CDM65514.1
gene_biotype: protein_coding
description:
  CRISPR-associated protein, Csx4 family; PFAM: CRISPR-associated protein GSU0053 (Cas_GSU0053); TIGRFAM: CRISPR-associated protein GSU0053/csb1, Dpsyc system.


ensembl_gene_id: PYK22_01518
symbol: CDM65515.1
gene_biotype: protein_coding
description:
  CRISPR-associated protein GSU0054/csb2, Dpsyc system; PFAM: CRISPR-associated protein, GSU0054 family (Cas_GSU0054); TIGRFAM: CRISPR-associated protein GSU0054/csb2, Dpsyc system.


ensembl_gene_id: PYK22_01521
symbol: CDM65518.1
gene_biotype: protein_coding
description:
  PFAM: Protein of unknown function (DUF310); TIGRFAM: CRISPR type III-A/MTUBE-associated protein Csm2.


ensembl_gene_id: PYK22_01524
symbol: CDM65521.1
gene_biotype: protein_coding
description:
  PFAM: CRISPR-associated protein (Cas_APE2256); TIGRFAM: putative CRISPR-associated protein, APE2256 family.


ensembl_gene_id: PYK22_01527
symbol: CDM65524.1
gene_biotype: protein_coding
description:
  Helicase family protein with metal-binding cysteine cluster; PFAM: Helicase conserved C-terminal domain; Domain of unknown function (DUF1998); DEAD/DEAH box helicase.


ensembl_gene_id: PYK22_01528
symbol: cas1
gene_biotype: protein_coding
description:
  CRISPR-associated protein, Cas1 family/CRISPR-associated exonuclease, Cas4 family; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.


ensembl_gene_id: PYK22_01530
symbol: cas2
gene_biotype: protein_coding
description:
  CRISPR-associated protein, Cas2 family; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.


ensembl_gene_id: PYK22_01532
symbol: CDM65529.1
gene_biotype: protein_coding
description:
  Ferrous iron transporter FeoB; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.


ensembl_gene_id: PYK22_01536
symbol: acsA
gene_biotype: protein_coding
description:
  Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.


ensembl_gene_id: PYK22_01537
symbol: CDM65534.1
gene_biotype: protein_coding
description:
  PFAM: DNA polymerase III, delta subunit, C terminal; DNA polymerase III, delta subunit; TIGRFAM: DNA polymerase III, delta' subunit.


ensembl_gene_id: PYK22_01538
symbol: tmk
gene_biotype: protein_coding
description:
  Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.


ensembl_gene_id: PYK22_01539
symbol: hfq
gene_biotype: protein_coding
description:
  RNA chaperone Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.


ensembl_gene_id: PYK22_01540
symbol: miaA
gene_biotype: protein_coding
description:
  tRNA isopentenyltransferase MiaA; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.


ensembl_gene_id: PYK22_01546
symbol: CDM65543.1
gene_biotype: protein_coding
description:
  PFAM: Competence protein; Domain of unknown function (DUF4131); Metallo-beta-lactamase superfamily; TIGRFAM: ComEC/Rec2-related protein; DNA internalization-related competence protein ComEC/Rec2.


ensembl_gene_id: PYK22_01549
symbol: CDM65546.1
gene_biotype: protein_coding
description:
  Mannose-6-phosphate isomerase, type 2; PFAM: Mannose-6-phosphate isomerase; Glycosyl transferases group 1.


ensembl_gene_id: PYK22_01553
symbol: gcvPB
gene_biotype: protein_coding
description:
  Glycine dehydrogenase (decarboxylating) beta subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily.


ensembl_gene_id: PYK22_01554
symbol: gcvPA
gene_biotype: protein_coding
description:
  Glycine dehydrogenase (decarboxylating) alpha subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.


ensembl_gene_id: PYK22_01555
symbol: gcvH
gene_biotype: protein_coding
description:
  Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.


ensembl_gene_id: PYK22_01556
symbol: gcvT
gene_biotype: protein_coding
description:
  Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine.


ensembl_gene_id: PYK22_01565
symbol: CDM65562.1
gene_biotype: protein_coding
description:
  ABC-type transport system involved in cytochrome c biogenesis, permease component; PFAM: Cytochrome C assembly protein; TIGRFAM: cytochrome c-type biogenesis protein CcsB.


ensembl_gene_id: PYK22_01567
symbol: CDM65564.1
gene_biotype: protein_coding
description:
  Molybdenum cofactor synthesis domain; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.


ensembl_gene_id: PYK22_01573
symbol: CDM65568.1
gene_biotype: protein_coding
description:
  ABC-type transport system involved in multi-copper enzyme maturation, permease component; PFAM: ABC-2 family transporter protein.


ensembl_gene_id: PYK22_01581
symbol: CDM65576.1
gene_biotype: protein_coding
description:
  PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phospho-acceptor) domain.


ensembl_gene_id: PYK22_01584
symbol: CDM65579.1
gene_biotype: protein_coding
description:
  PFAM: Acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.


ensembl_gene_id: PYK22_01586
symbol: CDM65581.1
gene_biotype: protein_coding
description:
  3-deoxy-D-arabinoheptulosonate-7-phosphate synthase; PFAM: DAHP synthetase I family; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase.


ensembl_gene_id: PYK22_01589
symbol: CDM65584.1
gene_biotype: protein_coding
description:
  TIGR03663 family protein; PFAM: Dolichyl-phosphate-mannose-protein mannosyltransferase; TIGRFAM: TIGR03663 family protein.


ensembl_gene_id: PYK22_01592
symbol: ychF
gene_biotype: protein_coding
description:
  GTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.


ensembl_gene_id: PYK22_01593
symbol: CDM65588.1
gene_biotype: protein_coding
description:
  Type IV-A pilus assembly ATPase PilB; PFAM: Type II secretion system (T2SS), protein E, N-terminal domain; Type II/IV secretion system protein; TIGRFAM: type IV-A pilus assembly ATPase PilB.


ensembl_gene_id: PYK22_01597
symbol: CDM65592.1
gene_biotype: protein_coding
description:
  PAS domain S-box; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phospho-acceptor) domain; PAS domain; TIGRFAM: PAS domain S-box.


ensembl_gene_id: PYK22_01607
symbol: CDM65602.1
gene_biotype: protein_coding
description:
  Periplasmic component of the Tol biopolymer transport system; PFAM: Bacterial Ig-like domain (group 2); WD40-like Beta Propeller Repeat; Lamin Tail Domain; TIGRFAM: Solibacter uncharacterized C-terminal domain.


ensembl_gene_id: PYK22_01611
symbol: purA
gene_biotype: protein_coding
description:
  Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.


ensembl_gene_id: PYK22_01615
symbol: rho
gene_biotype: protein_coding
description:
  Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.


ensembl_gene_id: PYK22_01616
symbol: engB
gene_biotype: protein_coding
description:
  Ribosome biogenesis GTP-binding protein YsxC/EngB; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.


ensembl_gene_id: PYK22_01617
symbol: smc
gene_biotype: protein_coding
description:
  Condensin subunit Smc; Required for chromosome condensation and partitioning. Belongs to the SMC family.


ensembl_gene_id: PYK22_01623
symbol: CDM65618.1
gene_biotype: protein_coding
description:
  PFAM: Elongation Factor G, domain II; Elongation factor Tu domain 2; Elongation factor G C-terminus; Elongation factor Tu GTP binding domain; Elongation factor G, domain IV; TIGRFAM: translation elongation factor EF-G; small GTP-binding protein domain.


ensembl_gene_id: PYK22_01627
symbol: CDM65622.1
gene_biotype: protein_coding
description:
  PFAM: Carbohydrate phosphorylase; Protein of unknown function (DUF3417); TIGRFAM: alpha-glucan phosphorylases.


ensembl_gene_id: PYK22_01631
symbol: CDM65626.1
gene_biotype: protein_coding
description:
  Flagellar biosynthesis pathway, component FlhB; PFAM: FlhB HrpN YscU SpaS Family; TIGRFAM: flagellar biosynthetic protein FlhB.


ensembl_gene_id: PYK22_01632
symbol: CDM65627.1
gene_biotype: protein_coding
description:
  Flagellar biosynthesis pathway, component FliR; PFAM: Bacterial export proteins, family 1; TIGRFAM: flagellar biosynthetic protein FliR.


ensembl_gene_id: PYK22_01634
symbol: fliP
gene_biotype: protein_coding
description:
  Flagellar biosynthetic protein FliP; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family.


ensembl_gene_id: PYK22_01636
symbol: CDM65631.1
gene_biotype: protein_coding
description:
  Flagellar motor switch/type III secretory pathway protein; PFAM: Surface presentation of antigens (SPOA); TIGRFAM: flagellar motor switch protein FliN.


ensembl_gene_id: PYK22_01637
symbol: CDM65632.1
gene_biotype: protein_coding
description:
  Flagellar basal body-associated protein; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.


ensembl_gene_id: PYK22_01640
symbol: CDM65635.1
gene_biotype: protein_coding
description:
  PFAM: Flagellar basal body rod FlgEFG protein C-terminal; Flagella basal body rod protein; Flagellar basal body protein FlaE; TIGRFAM: flagellar hook-basal body protein.


ensembl_gene_id: PYK22_01644
symbol: CDM65639.1
gene_biotype: protein_coding
description:
  Type III secretion system ATPase, FliI/YscN; PFAM: ATP synthase alpha/beta family, beta-barrel domain; ATP synthase alpha/beta family, nucleotide-binding domain; TIGRFAM: ATPase FliI/YscN family.


ensembl_gene_id: PYK22_01646
symbol: CDM65641.1
gene_biotype: protein_coding
description:
  Flagellar motor switch protein FliG; PFAM: FliG middle domain; FliG C-terminal domain; FliG N-terminal domain; TIGRFAM: flagellar motor switch protein FliG.


ensembl_gene_id: PYK22_01647
symbol: CDM65642.1
gene_biotype: protein_coding
description:
  Flagellar basal-body M-ring protein/flagellar hook-basal body protein FliF; The M ring may be actively involved in energy transduction. Belongs to the FliF family.


ensembl_gene_id: PYK22_01648
symbol: fliE
gene_biotype: protein_coding
description:
  PFAM: Flagellar hook-basal body complex protein FliE; TIGRFAM: flagellar hook-basal body complex protein FliE.


ensembl_gene_id: PYK22_01649
symbol: CDM65644.1
gene_biotype: protein_coding
description:
  PFAM: Flagellar basal body rod FlgEFG protein C-terminal; Flagella basal body rod protein; TIGRFAM: flagellar basal-body rod protein FlgC; Belongs to the flagella basal body rod proteins family.


ensembl_gene_id: PYK22_01650
symbol: CDM65645.1
gene_biotype: protein_coding
description:
  Flagellar basal-body rod protein FlgB; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.


ensembl_gene_id: PYK22_01654
symbol: flhA
gene_biotype: protein_coding
description:
  Flagellar biosynthesis protein FlhA; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.


ensembl_gene_id: PYK22_01657
symbol: CDM65652.1
gene_biotype: protein_coding
description:
  RNA polymerase, sigma 28 subunit, SigD/FliA/WhiG; PFAM: Sigma-70, region 4; Sigma-70 region 3; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, FliA/WhiG family; RNA polymerase sigma factor, sigma-70 family.


ensembl_gene_id: PYK22_01658
symbol: CDM65653.1
gene_biotype: protein_coding
description:
  PFAM: Surface presentation of antigens (SPOA); Flagellar motor switch protein FliM; TIGRFAM: flagellar motor switch protein FliM.


ensembl_gene_id: PYK22_01659
symbol: CDM65654.1
gene_biotype: protein_coding
description:
  Flagellar motor switch protein FliN; PFAM: Surface presentation of antigens (SPOA); TIGRFAM: flagellar motor switch protein FliN.


ensembl_gene_id: PYK22_01661
symbol: CDM65656.1
gene_biotype: protein_coding
description:
  PFAM: Flagellar basal body rod FlgEFG protein C-terminal; Flagella basal body rod protein; TIGRFAM: flagellar basal-body rod protein FlgF; flagellar hook-basal body protein.


ensembl_gene_id: PYK22_01669
symbol: CDM65664.1
gene_biotype: protein_coding
description:
  PAS domain S-box; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phospho-acceptor) domain; PAS domain; TIGRFAM: PAS domain S-box.


ensembl_gene_id: PYK22_01671
symbol: CDM65666.1
gene_biotype: protein_coding
description:
  PFAM: Citrate synthase; TIGRFAM: 2-methylcitrate synthase/citrate synthase II; Belongs to the citrate synthase family.


ensembl_gene_id: PYK22_01674
symbol: iscS
gene_biotype: protein_coding
description:
  Cysteine desulfurase family protein; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.


ensembl_gene_id: PYK22_01676
symbol: CDM65671.1
gene_biotype: protein_coding
description:
  MAF protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.


ensembl_gene_id: PYK22_01678
symbol: gatC
gene_biotype: protein_coding
description:
  aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family.


ensembl_gene_id: PYK22_01679
symbol: gatA
gene_biotype: protein_coding
description:
  aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln).


ensembl_gene_id: PYK22_01682
symbol: CDM65677.1
gene_biotype: protein_coding
description:
  Undecaprenyl pyrophosphate synthetase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.


ensembl_gene_id: PYK22_01683
symbol: truA
gene_biotype: protein_coding
description:
  tRNA pseudouridine(38-40) synthase; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.


ensembl_gene_id: PYK22_01684
symbol: pyrE
gene_biotype: protein_coding
description:
  Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).


ensembl_gene_id: PYK22_01690
symbol: CDM65685.1
gene_biotype: protein_coding
description:
  Cation/multidrug efflux pump; PFAM: AcrB/AcrD/AcrF family; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: PYK22_01698
symbol: CDM65693.1
gene_biotype: protein_coding
description:
  DNA/RNA helicase, superfamily I; PFAM: UvrD-like helicase C-terminal domain; UvrD/REP helicase N-terminal domain; TIGRFAM: ATP-dependent DNA helicase PcrA.


ensembl_gene_id: PYK22_01702
symbol: CDM65697.1
gene_biotype: protein_coding
description:
  Alpha-1,2-mannosidase, putative; PFAM: Glycosyl hydrolase family 92; TIGRFAM: alpha-1,2-mannosidase, putative.


ensembl_gene_id: PYK22_01707
symbol: CDM65701.1
gene_biotype: protein_coding
description:
  PFAM: Aconitase C-terminal domain; Aconitase family (aconitate hydratase); TIGRFAM: aconitate hydratase 1.


ensembl_gene_id: PYK22_01711
symbol: rpsO
gene_biotype: protein_coding
description:
  Ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.


ensembl_gene_id: PYK22_01712
symbol: pnp
gene_biotype: protein_coding
description:
  Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.


ensembl_gene_id: PYK22_01716
symbol: glyQS
gene_biotype: protein_coding
description:
  glycyl-tRNA synthetase; Catalyzes the attachment of glycine to tRNA(Gly). Belongs to the class-II aminoacyl-tRNA synthetase family.


ensembl_gene_id: PYK22_01720
symbol: CDM65714.1
gene_biotype: protein_coding
description:
  PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain; Belongs to the FGGY kinase family.


ensembl_gene_id: PYK22_01721
symbol: CDM65715.1
gene_biotype: protein_coding
description:
  Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.


ensembl_gene_id: PYK22_01724
symbol: trpD
gene_biotype: protein_coding
description:
  Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).


ensembl_gene_id: PYK22_01725
symbol: CDM65719.1
gene_biotype: protein_coding
description:
  PFAM: Glutamine amidotransferase class-I; TIGRFAM: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase.


ensembl_gene_id: PYK22_01728
symbol: hisA
gene_biotype: protein_coding
description:
  1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino) imidazole-4-carboxamide isomerase; PFAM: Histidine biosynthesis protein; TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.


ensembl_gene_id: PYK22_01731
symbol: rsmG
gene_biotype: protein_coding
description:
  16S rRNA m(7)G-527 methyltransferase; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.


ensembl_gene_id: PYK22_01739
symbol: recR
gene_biotype: protein_coding
description:
  DNA replication and repair protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.


ensembl_gene_id: PYK22_01740
symbol: CDM65734.1
gene_biotype: protein_coding
description:
  DNA-binding protein, YbaB/EbfC family; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.


ensembl_gene_id: PYK22_01741
symbol: CDM65735.1
gene_biotype: protein_coding
description:
  DNA/RNA helicase, superfamily I; PFAM: UvrD-like helicase C-terminal domain; UvrD/REP helicase N-terminal domain.


ensembl_gene_id: PYK22_01744
symbol: CDM65738.1
gene_biotype: protein_coding
description:
  Dipeptidyl aminopeptidase/acylaminoacyl peptidase; PFAM: Prolyl oligopeptidase family; WD40-like Beta Propeller Repeat.


ensembl_gene_id: PYK22_01746
symbol: CDM65740.1
gene_biotype: protein_coding
description:
  Glyceraldehyde-3-phosphate dehydrogenase (NAD+); PFAM: Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.


ensembl_gene_id: PYK22_01748
symbol: tpiA
gene_biotype: protein_coding
description:
  Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.


ensembl_gene_id: PYK22_01749
symbol: CDM65743.1
gene_biotype: protein_coding
description:
  Protein translocase subunit secG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.


ensembl_gene_id: PYK22_01758
symbol: CDM65751.1
gene_biotype: protein_coding
description:
  Carboxylate-amine ligase, YbdK family; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.


ensembl_gene_id: PYK22_01759
symbol: CDM65752.1
gene_biotype: protein_coding
description:
  PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; HAD-superfamily hydrolase, subfamily IIB.


ensembl_gene_id: PYK22_01764
symbol: CDM65757.1
gene_biotype: protein_coding
description:
  DNA-binding protein with winged-HTH domain; PFAM: WD40-like Beta Propeller Repeat; Transcriptional regulatory protein, C terminal.


ensembl_gene_id: PYK22_01767
symbol: CDM65760.1
gene_biotype: protein_coding
description:
  Predicted metal-dependent protease of the PAD1/JAB1 superfamily; PFAM: Prokaryotic homologs of the JAB domain.


ensembl_gene_id: PYK22_01768
symbol: aspS
gene_biotype: protein_coding
description:
  aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.


ensembl_gene_id: PYK22_01770
symbol: CDM65763.1
gene_biotype: protein_coding
description:
  Isoleucine patch superfamily enzyme, carbonic anhydrase/acetyltransferase; PFAM: Bacterial transferase hexapeptide (six repeats).


ensembl_gene_id: PYK22_01773
symbol: CDM65766.1
gene_biotype: protein_coding
description:
  Uncharacterized protein, YfiH family; PFAM: Multi-copper polyphenol oxidoreductase laccase; TIGRFAM: uncharacterized protein, YfiH family; Belongs to the multicopper oxidase YfiH/RL5 family.


ensembl_gene_id: PYK22_01777
symbol: CDM65770.1
gene_biotype: protein_coding
description:
  Beta-barrel assembly machine subunit BamA; PFAM: Surface antigen variable number repeat; Surface antigen; TIGRFAM: outer membrane protein assembly complex, YaeT protein.


ensembl_gene_id: PYK22_01779
symbol: ribB
gene_biotype: protein_coding
description:
  3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.


ensembl_gene_id: PYK22_01784
symbol: CDM65777.1
gene_biotype: protein_coding
description:
  Putative oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.


ensembl_gene_id: PYK22_01787
symbol: CDM65780.1
gene_biotype: protein_coding
description:
  Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.


ensembl_gene_id: PYK22_01789
symbol: CDM65782.1
gene_biotype: protein_coding
description:
  Methylase of chemotaxis methyl-accepting protein; PFAM: CheR methyltransferase, SAM binding domain; CheR methyltransferase, all-alpha domain.


ensembl_gene_id: PYK22_01791
symbol: CDM65784.1
gene_biotype: protein_coding
description:
  Alkylhydroperoxidase AhpD family core domain; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.


ensembl_gene_id: PYK22_01794
symbol: CDM65787.1
gene_biotype: protein_coding
description:
  PFAM: 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain.


ensembl_gene_id: PYK22_01795
symbol: ribH
gene_biotype: protein_coding
description:
  6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.


ensembl_gene_id: PYK22_01796
symbol: nusB
gene_biotype: protein_coding
description:
  NusB antitermination factor; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.


ensembl_gene_id: PYK22_01797
symbol: CDM65790.1
gene_biotype: protein_coding
description:
  Chemotaxis protein histidine kinase-like protein; PFAM: CheW-like domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Hpt domain.


ensembl_gene_id: PYK22_01803
symbol: CDM65796.1
gene_biotype: protein_coding
description:
  PFAM: Dehydrogenase E1 component; 2-oxoacid dehydrogenases acyltransferase (catalytic domain); Transketolase, pyrimidine binding domain; TIGRFAM: 2-oxoglutarate dehydrogenase, E1 component.


ensembl_gene_id: PYK22_01809
symbol: CDM65802.1
gene_biotype: protein_coding
description:
  PAS domain S-box; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; Response regulator receiver domain; His Kinase A (phospho-acceptor) domain; PAS domain; PAS fold; TIGRFAM: PAS domain S-box.


ensembl_gene_id: PYK22_01813
symbol: queG
gene_biotype: protein_coding
description:
  Epoxyqueuosine reductase; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family.


ensembl_gene_id: PYK22_01817
symbol: CDM65810.1
gene_biotype: protein_coding
description:
  Aminopeptidase N; PFAM: Peptidase family M1; ERAP1-like C-terminal domain; TIGRFAM: aminopeptidase N, Streptomyces lividans type.


ensembl_gene_id: PYK22_01823
symbol: CDM65816.1
gene_biotype: protein_coding
description:
  Ribonucleoside-diphosphate reductase class II; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.


ensembl_gene_id: PYK22_01824
symbol: CDM65817.1
gene_biotype: protein_coding
description:
  Ribonucleotide reductase, beta subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.


ensembl_gene_id: PYK22_01825
symbol: metE
gene_biotype: protein_coding
description:
  Methionine synthase (B12-independent); Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.


ensembl_gene_id: PYK22_01829
symbol: CDM65822.1
gene_biotype: protein_coding
description:
  TonB family protein; PFAM: Domain of unknown function (DUF4388); TIGRFAM: TonB family C-terminal domain.


ensembl_gene_id: PYK22_01832
symbol: gpmI
gene_biotype: protein_coding
description:
  Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.


ensembl_gene_id: PYK22_01833
symbol: eno
gene_biotype: protein_coding
description:
  Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.


ensembl_gene_id: PYK22_01836
symbol: CDM65829.1
gene_biotype: protein_coding
description:
  Outer membrane receptor protein; PFAM: TonB dependent receptor; TonB-dependent Receptor Plug Domain; Carboxypeptidase regulatory-like domain.


ensembl_gene_id: PYK22_01837
symbol: CDM65830.1
gene_biotype: protein_coding
description:
  Transcriptional regulator, CopG family; Transcriptional regulator; Belongs to the transcriptional regulatory CopG/NikR family.


ensembl_gene_id: PYK22_01851
symbol: CDM65844.1
gene_biotype: protein_coding
description:
  Subtilisin-like serine protease; PFAM: Domain of unknown function (DUF4214); Subtilase family; Belongs to the peptidase S8 family.


ensembl_gene_id: PYK22_01852
symbol: efp
gene_biotype: protein_coding
description:
  Translation elongation factor P (EF-P); Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.


ensembl_gene_id: PYK22_01853
symbol: CDM65846.1
gene_biotype: protein_coding
description:
  3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.


ensembl_gene_id: PYK22_01854
symbol: lpxK
gene_biotype: protein_coding
description:
  lipid-A-disaccharide kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).


ensembl_gene_id: PYK22_01860
symbol: CDM65852.1
gene_biotype: protein_coding
description:
  PFAM: NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase; NAD binding domain of 6-phosphogluconate dehydrogenase.


ensembl_gene_id: PYK22_01861
symbol: CDM65853.1
gene_biotype: protein_coding
description:
  RNA polymerase, sigma-24 subunit, RpoE; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family.


ensembl_gene_id: PYK22_01862
symbol: CDM65854.1
gene_biotype: protein_coding
description:
  Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides; PFAM: Antibiotic biosynthesis monooxygenase.


ensembl_gene_id: PYK22_01877
symbol: CDM65869.1
gene_biotype: protein_coding
description:
  Lignostilbene-alpha,beta-dioxygenase-like enzyme; PFAM: Retinal pigment epithelial membrane protein.


ensembl_gene_id: PYK22_01896
symbol: bioD
gene_biotype: protein_coding
description:
  Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.


ensembl_gene_id: PYK22_01902
symbol: CDM65894.1
gene_biotype: protein_coding
description:
  PFAM: Aminotransferase class-III; TIGRFAM: adenosylmethionine-8-amino-7-oxononanoate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: PYK22_01903
symbol: CDM65895.1
gene_biotype: protein_coding
description:
  Biotin biosynthesis protein BioZ; PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) synthase III.


ensembl_gene_id: PYK22_01904
symbol: CDM65896.1
gene_biotype: protein_coding
description:
  8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.


ensembl_gene_id: PYK22_01907
symbol: bioB
gene_biotype: protein_coding
description:
  Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.


ensembl_gene_id: PYK22_01911
symbol: CDM65903.1
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta); PFAM: Carboxyl transferase domain.


ensembl_gene_id: PYK22_01914
symbol: CDM65906.1
gene_biotype: protein_coding
description:
  Uncharacterized photosystem II stability/assembly factor-like protein; PFAM: Photosynthesis system II assembly factor YCF48.


ensembl_gene_id: PYK22_01916
symbol: CDM65908.1
gene_biotype: protein_coding
description:
  PFAM: Bacterial sugar transferase; CoA-binding domain; TIGRFAM: sugar transferase, PEP-CTERM system associated; exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase.


ensembl_gene_id: PYK22_01919
symbol: CDM65911.1
gene_biotype: protein_coding
description:
  Uncharacterized protein involved in exopolysaccharide biosynthesis; PFAM: Chain length determinant protein; G-rich domain on putative tyrosine kinase; TIGRFAM: polysaccharide chain length determinant protein, PEP-CTERM locus subfamily.


ensembl_gene_id: PYK22_01920
symbol: CDM65912.1
gene_biotype: protein_coding
description:
  PEP-CTERM putative exosortase interaction domain-containing protein; PFAM: PEP-CTERM motif; TIGRFAM: VPLPA-CTERM protein sorting domain; PEP-CTERM protein-sorting domain.


ensembl_gene_id: PYK22_01923
symbol: CDM65915.1
gene_biotype: protein_coding
description:
  PFAM: Transmembrane exosortase (Exosortase_EpsH); TIGRFAM: exosortase/archaeosortase family protein; exosortase.


ensembl_gene_id: PYK22_01928
symbol: CDM65919.1
gene_biotype: protein_coding
description:
  Predicted dehydrogenase; PFAM: Oxidoreductase family, NAD-binding Rossmann fold; Zinc-binding dehydrogenase.


ensembl_gene_id: PYK22_01934
symbol: lpxD
gene_biotype: protein_coding
description:
  UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily.


ensembl_gene_id: PYK22_01935
symbol: priA
gene_biotype: protein_coding
description:
  Replication restart DNA helicase PriA; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.


ensembl_gene_id: PYK22_01938
symbol: CDM65929.1
gene_biotype: protein_coding
description:
  Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.


ensembl_gene_id: PYK22_01943
symbol: CDM65934.1
gene_biotype: protein_coding
description:
  PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; TIGRFAM: nucleotide sugar dehydrogenase.


ensembl_gene_id: PYK22_01950
symbol: CDM65941.1
gene_biotype: protein_coding
description:
  Two component transcriptional regulator, LuxR family; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family.


ensembl_gene_id: PYK22_01951
symbol: CDM65942.1
gene_biotype: protein_coding
description:
  Predicted periplasmic ligand-binding sensor domain; PFAM: Histidine kinase; Y_Y_Y domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Two component regulator propeller.


ensembl_gene_id: PYK22_01953
symbol: CDM65944.1
gene_biotype: protein_coding
description:
  Hypothetical protein; PFAM: Carboxypeptidase regulatory-like domain; Tetratricopeptide repeat; TPR repeat.


ensembl_gene_id: PYK22_01954
symbol: queC
gene_biotype: protein_coding
description:
  Queuosine biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.


ensembl_gene_id: PYK22_01955
symbol: queE
gene_biotype: protein_coding
description:
  Organic radical activating enzyme; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.


ensembl_gene_id: PYK22_01959
symbol: CDM65950.1
gene_biotype: protein_coding
description:
  PP-loop superfamily ATP-utilizing enzyme; PFAM: ATP-binding region; TIGRFAM: MJ0570-related uncharacterized domain.


ensembl_gene_id: PYK22_01961
symbol: CDM65952.1
gene_biotype: protein_coding
description:
  PFAM: Aldehyde dehydrogenase family; TIGRFAM: glycine betaine aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: PYK22_01967
symbol: CDM65958.1
gene_biotype: protein_coding
description:
  Fe2+/Zn2+ uptake regulation protein; PFAM: Ferric uptake regulator family; Belongs to the Fur family.


ensembl_gene_id: PYK22_01975
symbol: CDM65966.1
gene_biotype: protein_coding
description:
  Competence/damage-inducible protein cinA; PFAM: Probable molybdopterin binding domain; Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA N-terminal domain; competence/damage-inducible protein CinA C-terminal domain; molybdenum cofactor synthesis domain.


ensembl_gene_id: PYK22_01978
symbol: plsY
gene_biotype: protein_coding
description:
  Acyl-phosphate glycerol 3-phosphate acyltransferase; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.


ensembl_gene_id: PYK22_01979
symbol: gpsA
gene_biotype: protein_coding
description:
  PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.


ensembl_gene_id: PYK22_01980
symbol: smpB
gene_biotype: protein_coding
description:
  SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]


ensembl_gene_id: PYK22_01981
symbol: pepA
gene_biotype: protein_coding
description:
  Leucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.


ensembl_gene_id: PYK22_01985
symbol: CDM65976.1
gene_biotype: protein_coding
description:
  ATPase family protein associated with various cellular activities (AAA); PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein.


ensembl_gene_id: PYK22_01987
symbol: CDM65978.1
gene_biotype: protein_coding
description:
  Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain; PFAM: Helix-turn-helix domain.


ensembl_gene_id: PYK22_01988
symbol: CDM65979.1
gene_biotype: protein_coding
description:
  (1->4)-alpha-D-glucan branching enzyme; PFAM: Domain of unknown function (DUF1957); Glycosyl hydrolase family 57; Belongs to the glycosyl hydrolase 57 family.


ensembl_gene_id: PYK22_01992
symbol: CDM65983.1
gene_biotype: protein_coding
description:
  PFAM: Glycosyltransferase family 9 (heptosyltransferase); TIGRFAM: lipopolysaccharide heptosyltransferase I.


ensembl_gene_id: PYK22_01993
symbol: CDM65984.1
gene_biotype: protein_coding
description:
  Cytidyltransferase-related enzyme; PFAM: Cytidylyltransferase; TIGRFAM: rfaE bifunctional protein, domain II; cytidyltransferase-like domain.


ensembl_gene_id: PYK22_01994
symbol: CDM65985.1
gene_biotype: protein_coding
description:
  ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase; PFAM: pfkB family carbohydrate kinase; TIGRFAM: rfaE bifunctional protein, domain I.


ensembl_gene_id: PYK22_01995
symbol: CDM65986.1
gene_biotype: protein_coding
description:
  Histidinol-phosphate phosphatase family protein; PFAM: HAD-hyrolase-like; TIGRFAM: HAD-superfamily hydrolase, subfamily IIIA; D,D-heptose 1,7-bisphosphate phosphatase; histidinol-phosphate phosphatase family domain.


ensembl_gene_id: PYK22_01996
symbol: CDM65987.1
gene_biotype: protein_coding
description:
  Lipopolysaccharide heptosyltransferase II; PFAM: Glycosyltransferase family 9 (heptosyltransferase); TIGRFAM: lipopolysaccharide heptosyltransferase II.


ensembl_gene_id: PYK22_01998
symbol: CDM65989.1
gene_biotype: protein_coding
description:
  Penicillin-binding protein, 1A family; PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase; TIGRFAM: penicillin-binding protein 1B; penicillin-binding protein, 1A family.


ensembl_gene_id: PYK22_01999
symbol: CDM65990.1
gene_biotype: protein_coding
description:
  Fe-S oxidoreductase; PFAM: Domain of unknown function (DUF4070); Radical SAM superfamily; B12 binding domain.


ensembl_gene_id: PYK22_02001
symbol: CDM65992.1
gene_biotype: protein_coding
description:
  Phosphoketolase; PFAM: XFP N-terminal domain; D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase; XFP C-terminal domain.


ensembl_gene_id: PYK22_02006
symbol: CDM65997.1
gene_biotype: protein_coding
description:
  P-type ATPase, translocating; PFAM: E1-E2 ATPase; Cation transporting ATPase, C-terminus; haloacid dehalogenase-like hydrolase; Cation transporter/ATPase, N-terminus; TIGRFAM: plasma-membrane calcium-translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC.


ensembl_gene_id: PYK22_02012
symbol: CDM66003.1
gene_biotype: protein_coding
description:
  Cytochrome bd-I ubiquinol oxidase subunit 1 apoprotein; PFAM: Bacterial Cytochrome Ubiquinol Oxidase; Belongs to the cytochrome ubiquinol oxidase subunit 1 family.


ensembl_gene_id: PYK22_02013
symbol: CDM66004.1
gene_biotype: protein_coding
description:
  Cytochrome bd-I ubiquinol oxidase subunit 2 apoprotein; PFAM: Cytochrome oxidase subunit II; TIGRFAM: cytochrome d oxidase, subunit II (cydB).


ensembl_gene_id: PYK22_02014
symbol: CDM66005.1
gene_biotype: protein_coding
description:
  Magnesium-translocating P-type ATPase; PFAM: E1-E2 ATPase; Cation transporting ATPase, C-terminus; haloacid dehalogenase-like hydrolase; Cation transporter/ATPase, N-terminus; TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; magnesium-translocating P-type ATPase.


ensembl_gene_id: PYK22_02016
symbol: CDM66007.1
gene_biotype: protein_coding
description:
  PAS domain S-box; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phospho-acceptor) domain; PAS domain; TIGRFAM: PAS domain S-box.


ensembl_gene_id: PYK22_02019
symbol: tilS
gene_biotype: protein_coding
description:
  tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.


ensembl_gene_id: PYK22_02020
symbol: ftsH
gene_biotype: protein_coding
description:
  Membrane protease FtsH catalytic subunit; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.


ensembl_gene_id: PYK22_02021
symbol: CDM66012.1
gene_biotype: protein_coding
description:
  Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.


ensembl_gene_id: PYK22_02025
symbol: CDM66016.1
gene_biotype: protein_coding
description:
  Soluble lytic murein transglycosylase-like protein; PFAM: Transglycosylase SLT domain; Tetratricopeptide repeat.


ensembl_gene_id: PYK22_02031
symbol: zwf
gene_biotype: protein_coding
description:
  Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.


ensembl_gene_id: PYK22_02032
symbol: CDM66023.1
gene_biotype: protein_coding
description:
  6-phosphogluconate dehydrogenase (decarboxylating); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.


ensembl_gene_id: PYK22_02035
symbol: CDM66026.1
gene_biotype: protein_coding
description:
  Lactoylglutathione lyase-like lyase; PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily.


ensembl_gene_id: PYK22_02036
symbol: CDM66027.1
gene_biotype: protein_coding
description:
  PFAM: Low molecular weight phosphotyrosine protein phosphatase; TIGRFAM: arsenate reductase (thioredoxin).


ensembl_gene_id: PYK22_02037
symbol: CDM66028.1
gene_biotype: protein_coding
description:
  P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc-resistance associated protein; PFAM: LTXXQ motif family protein.


ensembl_gene_id: PYK22_02038
symbol: dxs
gene_biotype: protein_coding
description:
  1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.


ensembl_gene_id: PYK22_02042
symbol: nadK
gene_biotype: protein_coding
description:
  Predicted sugar kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.


ensembl_gene_id: PYK22_02043
symbol: CDM66034.1
gene_biotype: protein_coding
description:
  PFAM: Sodium:dicarboxylate symporter family; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: PYK22_02046
symbol: queF
gene_biotype: protein_coding
description:
  7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.


ensembl_gene_id: PYK22_02052
symbol: crcB
gene_biotype: protein_coding
description:
  Protein CrcB; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.


ensembl_gene_id: PYK22_02076
symbol: CDM66066.1
gene_biotype: protein_coding
description:
  dTDP-glucose 4,6-dehydratase; PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: dTDP-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.


ensembl_gene_id: PYK22_02077
symbol: CDM66067.1
gene_biotype: protein_coding
description:
  dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.


ensembl_gene_id: PYK22_02079
symbol: CDM66069.1
gene_biotype: protein_coding
description:
  N-acetylglucosamine-1-phosphate uridylyltransferase/acetyltransferase; PFAM: Bacterial transferase hexapeptide (six repeats).


ensembl_gene_id: PYK22_02083
symbol: mtgA
gene_biotype: protein_coding
description:
  Transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family.


ensembl_gene_id: PYK22_02090
symbol: rpmF
gene_biotype: protein_coding
description:
  PFAM: Ribosomal L32p protein family; TIGRFAM: ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family.


ensembl_gene_id: PYK22_02091
symbol: plsX
gene_biotype: protein_coding
description:
  Phosphate:acyl-(acyl carrier protein) acyltransferase; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.


ensembl_gene_id: PYK22_02092
symbol: fabH
gene_biotype: protein_coding
description:
  3-oxoacyl-(acyl-carrier-protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.


ensembl_gene_id: PYK22_02093
symbol: CDM66083.1
gene_biotype: protein_coding
description:
  (Acyl-carrier-protein) S-malonyltransferase; PFAM: Acyl transferase domain; TIGRFAM: malonyl CoA-acyl carrier protein transacylase.


ensembl_gene_id: PYK22_02095
symbol: CDM66085.1
gene_biotype: protein_coding
description:
  3-oxoacyl-(acyl-carrier-protein) synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.


ensembl_gene_id: PYK22_02105
symbol: trmFO
gene_biotype: protein_coding
description:
  tRNA:m(5)U-54 methyltransferase; Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs; Belongs to the MnmG family. TrmFO subfamily.


ensembl_gene_id: PYK22_02109
symbol: CDM66098.1
gene_biotype: protein_coding
description:
  Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin; PFAM: Phytanoyl-CoA dioxygenase (PhyH).


ensembl_gene_id: PYK22_02112
symbol: CDM66101.1
gene_biotype: protein_coding
description:
  Outer membrane cobalamin receptor protein; PFAM: TonB dependent receptor; TonB-dependent Receptor Plug Domain; Carboxypeptidase regulatory-like domain.


ensembl_gene_id: PYK22_02118
symbol: CDM66106.1
gene_biotype: protein_coding
description:
  ABC-type Fe3+-hydroxamate transport system, periplasmic component; PFAM: Periplasmic binding protein.


ensembl_gene_id: PYK22_02120
symbol: rpsL
gene_biotype: protein_coding
description:
  SSU ribosomal protein S12P; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.


ensembl_gene_id: PYK22_02121
symbol: rpsG
gene_biotype: protein_coding
description:
  SSU ribosomal protein S7P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.


ensembl_gene_id: PYK22_02122
symbol: fusA
gene_biotype: protein_coding
description:
  Translation elongation factor 2 (EF-2/EF-G); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. [...]


ensembl_gene_id: PYK22_02123
symbol: tuf
gene_biotype: protein_coding
description:
  Translation elongation factor 1A (EF-1A/EF-Tu); This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.


ensembl_gene_id: PYK22_02124
symbol: rpsJ
gene_biotype: protein_coding
description:
  SSU ribosomal protein S10P; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.


ensembl_gene_id: PYK22_02125
symbol: rplC
gene_biotype: protein_coding
description:
  LSU ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.


ensembl_gene_id: PYK22_02127
symbol: rplW
gene_biotype: protein_coding
description:
  LSU ribosomal protein L23P; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.


ensembl_gene_id: PYK22_02128
symbol: rplB
gene_biotype: protein_coding
description:
  LSU ribosomal protein L2P; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.


ensembl_gene_id: PYK22_02129
symbol: rpsS
gene_biotype: protein_coding
description:
  SSU ribosomal protein S19P; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.


ensembl_gene_id: PYK22_02130
symbol: rplV
gene_biotype: protein_coding
description:
  Ribosomal protein L22, bacterial type; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.


ensembl_gene_id: PYK22_02131
symbol: rpsC
gene_biotype: protein_coding
description:
  SSU ribosomal protein S3P; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.


ensembl_gene_id: PYK22_02132
symbol: rplP
gene_biotype: protein_coding
description:
  LSU ribosomal protein L16P; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.


ensembl_gene_id: PYK22_02133
symbol: rpmC
gene_biotype: protein_coding
description:
  PFAM: Ribosomal L29 protein; TIGRFAM: ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family.


ensembl_gene_id: PYK22_02134
symbol: rpsQ
gene_biotype: protein_coding
description:
  30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.


ensembl_gene_id: PYK22_02135
symbol: rplN
gene_biotype: protein_coding
description:
  LSU ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.


ensembl_gene_id: PYK22_02136
symbol: rplX
gene_biotype: protein_coding
description:
  LSU ribosomal protein L24P; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.


ensembl_gene_id: PYK22_02137
symbol: rplE
gene_biotype: protein_coding
description:
  Ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.


ensembl_gene_id: PYK22_02138
symbol: rpsH
gene_biotype: protein_coding
description:
  SSU ribosomal protein S8P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.


ensembl_gene_id: PYK22_02139
symbol: rplF
gene_biotype: protein_coding
description:
  Ribosomal protein L6, bacterial type; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.


ensembl_gene_id: PYK22_02140
symbol: rplR
gene_biotype: protein_coding
description:
  Ribosomal protein L18, bacterial type; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.


ensembl_gene_id: PYK22_02141
symbol: rpsE
gene_biotype: protein_coding
description:
  SSU ribosomal protein S5P; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.


ensembl_gene_id: PYK22_02143
symbol: rplO
gene_biotype: protein_coding
description:
  LSU ribosomal protein L15P; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.


ensembl_gene_id: PYK22_02144
symbol: secY
gene_biotype: protein_coding
description:
  Protein translocase subunit secY/sec61 alpha; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.


ensembl_gene_id: PYK22_02145
symbol: adk
gene_biotype: protein_coding
description:
  Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.


ensembl_gene_id: PYK22_02146
symbol: map
gene_biotype: protein_coding
description:
  Methionine aminopeptidase, type I; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.


ensembl_gene_id: PYK22_02147
symbol: infA
gene_biotype: protein_coding
description:
  Bacterial translation initiation factor 1 (bIF-1); One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.


ensembl_gene_id: PYK22_02148
symbol: rpmJ
gene_biotype: protein_coding
description:
  PFAM: Ribosomal protein L36; TIGRFAM: ribosomal protein L36, bacterial type; Belongs to the bacterial ribosomal protein bL36 family.


ensembl_gene_id: PYK22_02149
symbol: rpsM
gene_biotype: protein_coding
description:
  30S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family.


ensembl_gene_id: PYK22_02150
symbol: rpsK
gene_biotype: protein_coding
description:
  30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.


ensembl_gene_id: PYK22_02151
symbol: rpsD
gene_biotype: protein_coding
description:
  Ribosomal protein S4, bacterial/organelle type; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.


ensembl_gene_id: PYK22_02152
symbol: rpoA
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: PYK22_02154
symbol: CDM66142.1
gene_biotype: protein_coding
description:
  Biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.


ensembl_gene_id: PYK22_02155
symbol: CDM66143.1
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.


ensembl_gene_id: PYK22_02156
symbol: rplU
gene_biotype: protein_coding
description:
  LSU ribosomal protein L21P; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.


ensembl_gene_id: PYK22_02157
symbol: rpmA
gene_biotype: protein_coding
description:
  PFAM: Ribosomal L27 protein; TIGRFAM: ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family.


ensembl_gene_id: PYK22_02158
symbol: obg
gene_biotype: protein_coding
description:
  Obg family GTPase CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.


ensembl_gene_id: PYK22_02159
symbol: nadD
gene_biotype: protein_coding
description:
  Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).


ensembl_gene_id: PYK22_02160
symbol: rsfS
gene_biotype: protein_coding
description:
  Iojap-like ribosome-associated protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.


ensembl_gene_id: PYK22_02162
symbol: rlmH
gene_biotype: protein_coding
description:
  Hypothetical protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family.


ensembl_gene_id: PYK22_02164
symbol: CDM66152.1
gene_biotype: protein_coding
description:
  Predicted amidophosphoribosyltransferase; PFAM: Phosphoribosyl transferase domain; TIGRFAM: comF family protein.


ensembl_gene_id: PYK22_02166
symbol: CDM66154.1
gene_biotype: protein_coding
description:
  Siroheme synthase, N-terminal domain; PFAM: Putative NAD(P)-binding; Sirohaem synthase dimerisation region; TIGRFAM: siroheme synthase, N-terminal domain.


ensembl_gene_id: PYK22_02168
symbol: cysH
gene_biotype: protein_coding
description:
  Phosphoadenylylsulfate reductase (thioredoxin); Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.


ensembl_gene_id: PYK22_02169
symbol: CDM66157.1
gene_biotype: protein_coding
description:
  Sulfite reductase (ferredoxin); PFAM: ThiS family; Nitrite and sulphite reductase 4Fe-4S domain; Nitrite/Sulfite reductase ferredoxin-like half domain.


ensembl_gene_id: PYK22_02174
symbol: CDM66162.1
gene_biotype: protein_coding
description:
  AMP-forming long-chain acyl-CoA synthetase; PFAM: Phosphopantetheine attachment site; Acyltransferase; AMP-binding enzyme; AMP-binding enzyme C-terminal domain.


ensembl_gene_id: PYK22_02175
symbol: pyrR
gene_biotype: protein_coding
description:
  Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.


ensembl_gene_id: PYK22_02176
symbol: pyrB
gene_biotype: protein_coding
description:
  PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFAM: aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.


ensembl_gene_id: PYK22_02177
symbol: pyrC
gene_biotype: protein_coding
description:
  Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.


ensembl_gene_id: PYK22_02183
symbol: CDM66171.1
gene_biotype: protein_coding
description:
  Cysteine synthase; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase; cysteine synthase B.


ensembl_gene_id: PYK22_02185
symbol: CDM66173.1
gene_biotype: protein_coding
description:
  MoaD family protein; PFAM: ThiS family; MoeZ/MoeB domain; Rhodanese-like domain; ThiF family; TIGRFAM: MoaD family protein, archaeal.


ensembl_gene_id: PYK22_02186
symbol: CDM66174.1
gene_biotype: protein_coding
description:
  ABC-type transport system involved in resistance to organic solvents, periplasmic component; PFAM: mce related protein.


ensembl_gene_id: PYK22_02187
symbol: CDM66175.1
gene_biotype: protein_coding
description:
  ABC-type transport system involved in resistance to organic solvents, ATPase component; PFAM: ABC transporter.


ensembl_gene_id: PYK22_02188
symbol: CDM66176.1
gene_biotype: protein_coding
description:
  PFAM: Permease; TIGRFAM: conserved hypothetical integral membrane protein; Belongs to the MlaE permease family.


ensembl_gene_id: PYK22_02193
symbol: ftsY
gene_biotype: protein_coding
description:
  Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).


ensembl_gene_id: PYK22_02194
symbol: CDM66182.1
gene_biotype: protein_coding
description:
  Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.


ensembl_gene_id: PYK22_02195
symbol: rsmA
gene_biotype: protein_coding
description:
  Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.


ensembl_gene_id: PYK22_02197
symbol: rnj
gene_biotype: protein_coding
description:
  Predicted hydrolase of the metallo-beta-lactamase superfamily; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.


ensembl_gene_id: PYK22_02198
symbol: CDM66186.1
gene_biotype: protein_coding
description:
  Short-chain dehydrogenase of unknown substrate specificity; PFAM: short chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: PYK22_02199
symbol: uppP
gene_biotype: protein_coding
description:
  Undecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.


ensembl_gene_id: PYK22_02200
symbol: CDM66188.1
gene_biotype: protein_coding
description:
  Exonuclease RecJ; PFAM: DHHA1 domain; DHH family; TIGRFAM: single-stranded-DNA-specific exonuclease RecJ.


ensembl_gene_id: PYK22_02203
symbol: CDM66191.1
gene_biotype: protein_coding
description:
  RNA polymerase, sigma 54 subunit, RpoN/SigL; PFAM: Sigma-54 factor, Activator interacting domain (AID); Sigma-54, DNA binding domain; Sigma-54 factor, core binding domain; TIGRFAM: RNA polymerase sigma-54 factor.


ensembl_gene_id: PYK22_02204
symbol: CDM66192.1
gene_biotype: protein_coding
description:
  PFAM: Sigma 54 modulation protein / S30EA ribosomal protein; TIGRFAM: ribosomal subunit interface protein.


ensembl_gene_id: PYK22_02205
symbol: hprK
gene_biotype: protein_coding
description:
  Hpr(Ser) kinase/phosphatase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).


ensembl_gene_id: PYK22_02207
symbol: CDM66195.1
gene_biotype: protein_coding
description:
  PFAM: PTS system fructose IIA component; TIGRFAM: PTS system, mannose/fructose/sorbose family, IIA component.


ensembl_gene_id: PYK22_02209
symbol: CDM66197.1
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).


ensembl_gene_id: PYK22_02216
symbol: CDM66202.1
gene_biotype: protein_coding
description:
  Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.


ensembl_gene_id: PYK22_02223
symbol: CDM66209.1
gene_biotype: protein_coding
description:
  Type IV pilus secretin PilQ/competence protein; PFAM: Bacterial type II/III secretion system short domain; Bacterial type II and III secretion system protein; TIGRFAM: type IV pilus secretin (or competence protein) PilQ.


ensembl_gene_id: PYK22_02230
symbol: tatA
gene_biotype: protein_coding
description:
  Twin arginine-targeting protein translocase, TatA/E family; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.


ensembl_gene_id: PYK22_02231
symbol: radA
gene_biotype: protein_coding
description:
  DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.


ensembl_gene_id: PYK22_02233
symbol: CDM66218.1
gene_biotype: protein_coding
description:
  Penicillin-binding protein, 1A family; PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase; TIGRFAM: penicillin-binding protein, 1A family.


ensembl_gene_id: PYK22_02235
symbol: CDM66220.1
gene_biotype: protein_coding
description:
  Indolepyruvate ferredoxin oxidreductase, alpha/beta subunit; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.


ensembl_gene_id: PYK22_02236
symbol: purH
gene_biotype: protein_coding
description:
  PFAM: AICARFT/IMPCHase bienzyme; MGS-like domain; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase.


ensembl_gene_id: PYK22_02238
symbol: CDM66223.1
gene_biotype: protein_coding
description:
  birA, biotin-(acetyl-CoA-carboxylase) ligase; PFAM: Biotin protein ligase C terminal domain; Biotin/lipoate A/B protein ligase family; TIGRFAM: birA, biotin-[acetyl-CoA-carboxylase] ligase region.


ensembl_gene_id: PYK22_02240
symbol: rpoZ
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.


ensembl_gene_id: PYK22_02242
symbol: CDM66227.1
gene_biotype: protein_coding
description:
  TIGR00255 family protein; PFAM: YicC-like family, N-terminal region; Domain of unknown function (DUF1732); TIGRFAM: TIGR00255 family protein.


ensembl_gene_id: PYK22_02243
symbol: CDM66228.1
gene_biotype: protein_coding
description:
  ABC-type multidrug transport system, ATPase and permease component; PFAM: ABC transporter; ABC transporter transmembrane region; TIGRFAM: lipid A export permease/ATP-binding protein MsbA.


ensembl_gene_id: PYK22_02249
symbol: CDM66233.1
gene_biotype: protein_coding
description:
  PFAM: Uncharacterised protein family UPF0047; TIGRFAM: secondary thiamine-phosphate synthase enzyme.


ensembl_gene_id: PYK22_02250
symbol: gmhA
gene_biotype: protein_coding
description:
  Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate; Belongs to the SIS family. GmhA subfamily.


ensembl_gene_id: PYK22_02252
symbol: CDM66236.1
gene_biotype: protein_coding
description:
  PFAM: CDP-alcohol phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: PYK22_02258
symbol: CDM66238.1
gene_biotype: protein_coding
description:
  Translation elongation factor-like GTPase; PFAM: Elongation factor Tu GTP binding domain; TIGRFAM: small GTP-binding protein domain; translation elongation factor TU.


ensembl_gene_id: PYK22_02261
symbol: CDM66241.1
gene_biotype: protein_coding
description:
  Nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; TIGRFAM: nucleotide sugar dehydrogenase.


ensembl_gene_id: PYK22_02262
symbol: CDM66242.1
gene_biotype: protein_coding
description:
  Methyltransferase, FkbM family; PFAM: Methyltransferase FkbM domain; TIGRFAM: methyltransferase, FkbM family.


ensembl_gene_id: PYK22_02274
symbol: CDM66254.1
gene_biotype: protein_coding
description:
  Asparagine synthase, glutamine-hydrolyzing; PFAM: Glutamine amidotransferase domain; Asparagine synthase; TIGRFAM: asparagine synthase (glutamine-hydrolyzing); exosortase A system-associated amidotransferase 1.


ensembl_gene_id: PYK22_02291
symbol: CDM66271.1
gene_biotype: protein_coding
description:
  Lipid A core-O-antigen ligase-like enyme; PFAM: O-antigen ligase like membrane protein; TIGRFAM: probable O-glycosylation ligase, exosortase A-associated.


ensembl_gene_id: PYK22_02298
symbol: CDM66278.1
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase; PFAM: CoA-binding domain; Glycosyl transferase family 4.


ensembl_gene_id: PYK22_02303
symbol: rimO
gene_biotype: protein_coding
description:
  SSU ribosomal protein S12P methylthiotransferase; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily.


ensembl_gene_id: PYK22_02304
symbol: CDM66284.1
gene_biotype: protein_coding
description:
  Transglutaminase-like enzyme, predicted cysteine protease; PFAM: Transglutaminase-like superfamily; Domain of unknown function (DUF4129); Domain of unknown function (DUF3488).


ensembl_gene_id: PYK22_02313
symbol: secF
gene_biotype: protein_coding
description:
  16S ribosomal RNA. Bacterial SSU; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.


ensembl_gene_id: PYK22_02314
symbol: secD
gene_biotype: protein_coding
description:
  Protein-export membrane protein, SecD/SecF family; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.


ensembl_gene_id: PYK22_02316
symbol: tgt
gene_biotype: protein_coding
description:
  tRNA-guanine transglycosylase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the [...]


ensembl_gene_id: PYK22_02317
symbol: der
gene_biotype: protein_coding
description:
  Ribosome-associated GTPase EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.


ensembl_gene_id: PYK22_02318
symbol: CDM66291.1
gene_biotype: protein_coding
description:
  Predicted endonuclease related to Holliday junction resolvase; PFAM: Uncharacterised protein family UPF0102; Belongs to the UPF0102 family.


ensembl_gene_id: PYK22_02319
symbol: dtd
gene_biotype: protein_coding
description:
  D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family.


ensembl_gene_id: PYK22_02321
symbol: gatB
gene_biotype: protein_coding
description:
  aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily.


ensembl_gene_id: PYK22_02325
symbol: mtnA
gene_biotype: protein_coding
description:
  Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).


ensembl_gene_id: PYK22_02329
symbol: recA
gene_biotype: protein_coding
description:
  Protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.


ensembl_gene_id: PYK22_02331
symbol: trpA
gene_biotype: protein_coding
description:
  Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.


ensembl_gene_id: PYK22_02332
symbol: trpB
gene_biotype: protein_coding
description:
  Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.


ensembl_gene_id: PYK22_02335
symbol: CDM66308.1
gene_biotype: protein_coding
description:
  PAS domain S-box; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; His Kinase A (phospho-acceptor) domain; PAS domain; CHASE3 domain; TIGRFAM: PAS domain S-box.


ensembl_gene_id: PYK22_02338
symbol: tsaD
gene_biotype: protein_coding
description:
  O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.


ensembl_gene_id: PYK22_02339
symbol: CDM66312.1
gene_biotype: protein_coding
description:
  RNA methyltransferase, RsmD family; PFAM: Conserved hypothetical protein 95; TIGRFAM: RNA methyltransferase, RsmD family.


ensembl_gene_id: PYK22_02341
symbol: lepA
gene_biotype: protein_coding
description:
  GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.


ensembl_gene_id: PYK22_02345
symbol: CDM66318.1
gene_biotype: protein_coding
description:
  Predicted kinase, galactokinase/mevalonate kinase; PFAM: GHMP kinases C terminal; GHMP kinases N terminal domain.


ensembl_gene_id: PYK22_02348
symbol: CDM66321.1
gene_biotype: protein_coding
description:
  Phosphate transport system regulatory protein PhoU; Plays a role in the regulation of phosphate uptake.


ensembl_gene_id: PYK22_02349
symbol: pstB
gene_biotype: protein_coding
description:
  Phosphate ABC transporter ATP-binding protein, PhoT family; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.


ensembl_gene_id: PYK22_02350
symbol: CDM66323.1
gene_biotype: protein_coding
description:
  PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: phosphate ABC transporter, permease protein PstA.


ensembl_gene_id: PYK22_02351
symbol: CDM66324.1
gene_biotype: protein_coding
description:
  Phosphate ABC transporter membrane protein 1, PhoT family; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: PYK22_02352
symbol: CDM66325.1
gene_biotype: protein_coding
description:
  PFAM: PBP superfamily domain; TIGRFAM: phosphate ABC transporter, phosphate-binding protein; Belongs to the PstS family.


ensembl_gene_id: PYK22_02358
symbol: CDM66331.1
gene_biotype: protein_coding
description:
  Actin-like ATPase involved in cell morphogenesis; PFAM: MreB/Mbl protein; TIGRFAM: cell shape determining protein, MreB/Mrl family.


ensembl_gene_id: PYK22_02359
symbol: CDM66332.1
gene_biotype: protein_coding
description:
  Zn-dependent protease; PFAM: CBS domain; Peptidase family M50; Belongs to the peptidase M50B family.


ensembl_gene_id: PYK22_02361
symbol: CDM66334.1
gene_biotype: protein_coding
description:
  Sigma-54 interacting regulator,GAF domain-containing protein; PFAM: GAF domain; Bacterial regulatory protein, Fis family; Sigma-54 interaction domain.


ensembl_gene_id: PYK22_02368
symbol: lpxA
gene_biotype: protein_coding
description:
  acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: PYK22_02369
symbol: fabZ
gene_biotype: protein_coding
description:
  3-hydroxyacyl-(acyl-carrier-protein) dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.


ensembl_gene_id: PYK22_02374
symbol: CDM66346.1
gene_biotype: protein_coding
description:
  ABC-type transport system, involved in lipoprotein release, permease component; PFAM: MacB-like periplasmic core domain; FtsX-like permease family; TIGRFAM: lipoprotein releasing system, transmembrane protein, LolC/E family.


ensembl_gene_id: PYK22_02376
symbol: CDM66348.1
gene_biotype: protein_coding
description:
  Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains; PFAM: Histidine kinase-like ATPase domain; Response regulator receiver domain.


ensembl_gene_id: PYK22_02378
symbol: CDM66350.1
gene_biotype: protein_coding
description:
  Peptidase T-like protein; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain; TIGRFAM: peptidase T-like protein.


ensembl_gene_id: PYK22_02380
symbol: era
gene_biotype: protein_coding
description:
  GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.


ensembl_gene_id: PYK22_02381
symbol: prmA
gene_biotype: protein_coding
description:
  Ribosomal protein L11 methylase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family.


ensembl_gene_id: PYK22_02382
symbol: CDM66354.1
gene_biotype: protein_coding
description:
  RNA methyltransferase, RsmE family; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.


ensembl_gene_id: PYK22_02388
symbol: mfd
gene_biotype: protein_coding
description:
  Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.


ensembl_gene_id: PYK22_02389
symbol: CDM66361.1
gene_biotype: protein_coding
description:
  D-heptose-1-phosphate adenylyltransferase; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.


ensembl_gene_id: PYK22_02390
symbol: lysS
gene_biotype: protein_coding
description:
  PFAM: tRNA synthetases class II (D, K and N); OB-fold nucleic acid binding domain; TIGRFAM: lysyl-tRNA synthetase, eukaryotic and non-spirochete bacterial; Belongs to the class-II aminoacyl-tRNA synthetase family.


ensembl_gene_id: PYK22_02391
symbol: CDM66363.1
gene_biotype: protein_coding
description:
  Putative NAD(P)H quinone oxidoreductase, PIG3 family; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; TIGRFAM: putative NAD(P)H quinone oxidoreductase, PIG3 family.


ensembl_gene_id: PYK22_02396
symbol: CDM66368.1
gene_biotype: protein_coding
description:
  Predicted extracellular nuclease; PFAM: Endonuclease/Exonuclease/phosphatase family; Lamin Tail Domain.


ensembl_gene_id: PYK22_02401
symbol: CDM66372.1
gene_biotype: protein_coding
description:
  Predicted membrane protein; PFAM: Virulence factor BrkB; TIGRFAM: YihY family inner membrane protein.


ensembl_gene_id: PYK22_02402
symbol: CDM66373.1
gene_biotype: protein_coding
description:
  PFAM: Peptidase S24-like; Signal peptidase, peptidase S26; TIGRFAM: signal peptidase I, bacterial type; Belongs to the peptidase S26 family.


ensembl_gene_id: PYK22_02403
symbol: rnc
gene_biotype: protein_coding
description:
  Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.


ensembl_gene_id: PYK22_02405
symbol: CDM66376.1
gene_biotype: protein_coding
description:
  Cell division protein FtsI/penicillin-binding protein 2; PFAM: Penicillin binding protein transpeptidase domain.


ensembl_gene_id: PYK22_02406
symbol: CDM66377.1
gene_biotype: protein_coding
description:
  PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phospho-acceptor) domain.


ensembl_gene_id: PYK22_02411
symbol: CDM66382.1
gene_biotype: protein_coding
description:
  Uncharacterized protein; PFAM: von Willebrand factor type A domain; TIGRFAM: VWFA-related Acidobacterial domain.


ensembl_gene_id: PYK22_02414
symbol: ruvC
gene_biotype: protein_coding
description:
  Holliday junction endonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.


ensembl_gene_id: PYK22_02416
symbol: CDM66387.1
gene_biotype: protein_coding
description:
  TIGR00251 family protein; PFAM: Uncharacterised ACR, YggU family COG1872; TIGRFAM: TIGR00251 family protein; Belongs to the UPF0235 family.


ensembl_gene_id: PYK22_02418
symbol: CDM66389.1
gene_biotype: protein_coding
description:
  Pyridoxal phosphate enzyme, YggS family; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.


ensembl_gene_id: PYK22_02422
symbol: ligA
gene_biotype: protein_coding
description:
  DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily.


ensembl_gene_id: PYK22_02426
symbol: CDM66396.1
gene_biotype: protein_coding
description:
  ABC-type dipeptide transport system, periplasmic component; PFAM: Methyl-accepting chemotaxis protein (MCP) signalling domain; Bacterial extracellular solute-binding proteins, family 5 Middle.


ensembl_gene_id: PYK22_02427
symbol: CDM66397.1
gene_biotype: protein_coding
description:
  DnaJ-class molecular chaperone with C-terminal Zn finger domain; PFAM: DnaJ domain; Domain of unknown function (DUF4388); TPR repeat.


ensembl_gene_id: PYK22_02432
symbol: CDM66402.1
gene_biotype: protein_coding
description:
  Ribonucleotide reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.


ensembl_gene_id: PYK22_02433
symbol: hslO
gene_biotype: protein_coding
description:
  Disulfide bond chaperone; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.


ensembl_gene_id: PYK22_02437
symbol: purD
gene_biotype: protein_coding
description:
  Phosphoribosylamine--glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, N domain; Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, C domain; TIGRFAM: phosphoribosylamine--glycine ligase; Belongs to the GARS family.


ensembl_gene_id: PYK22_02440
symbol: CDM66410.1
gene_biotype: protein_coding
description:
  PFAM: Trypsin-like peptidase domain; PDZ domain; TIGRFAM: periplasmic serine protease, Do/DeqQ family; periplasmic serine pepetdase DegS.


ensembl_gene_id: PYK22_02444
symbol: clpB
gene_biotype: protein_coding
description:
  ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.


ensembl_gene_id: PYK22_02445
symbol: ftsH-2
gene_biotype: protein_coding
description:
  Membrane protease FtsH catalytic subunit; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family.  In the central section; belongs to the AAA ATPase family.


ensembl_gene_id: PYK22_02448
symbol: dnaJ-2
gene_biotype: protein_coding
description:
  DnaJ-class molecular chaperone with C-terminal Zn finger domain; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of A [...]


ensembl_gene_id: PYK22_02453
symbol: CDM66423.1
gene_biotype: protein_coding
description:
  Phosphoglycerate dehydrogenase-like oxidoreductase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; ACT domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; TIGRFAM: D-3-phosphoglycerate dehydrogenase.


ensembl_gene_id: PYK22_02455
symbol: serC
gene_biotype: protein_coding
description:
  Phosphoserine aminotransferase apoenzyme; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.


ensembl_gene_id: PYK22_02456
symbol: CDM66426.1
gene_biotype: protein_coding
description:
  Periplasmic component of the Tol biopolymer transport system; PFAM: WD40-like Beta Propeller Repeat.


ensembl_gene_id: PYK22_02457
symbol: CDM66427.1
gene_biotype: protein_coding
description:
  Arabinose efflux permease family protein; PFAM: Major Facilitator Superfamily; TIGRFAM: Multidrug resistance protein.


ensembl_gene_id: PYK22_02459
symbol: CDM66429.1
gene_biotype: protein_coding
description:
  PFAM: Enoyl-CoA hydratase/isomerase family; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain.


ensembl_gene_id: PYK22_02463
symbol: CDM66433.1
gene_biotype: protein_coding
description:
  Predicted integral membrane protein; PFAM: Polyketide cyclase / dehydrase and lipid transport; BON domain.


ensembl_gene_id: PYK22_02470
symbol: sigA
gene_biotype: protein_coding
description:
  RNA polymerase, sigma 70 subunit, RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.


ensembl_gene_id: PYK22_02471
symbol: dnaG
gene_biotype: protein_coding
description:
  DNA primase, catalytic core; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.


ensembl_gene_id: PYK22_02472
symbol: mutS2
gene_biotype: protein_coding
description:
  MutS2 family protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.


ensembl_gene_id: PYK22_02473
symbol: cheB
gene_biotype: protein_coding
description:
  Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.


ensembl_gene_id: PYK22_02475
symbol: pckA
gene_biotype: protein_coding
description:
  ATP-dependent phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.


ensembl_gene_id: PYK22_02478
symbol: CDM66448.1
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydratase large subunit; PFAM: Aconitase C-terminal domain; Aconitase family (aconitate hydratase).


ensembl_gene_id: PYK22_02481
symbol: lipB
gene_biotype: protein_coding
description:
  Lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.


ensembl_gene_id: PYK22_02483
symbol: lipA
gene_biotype: protein_coding
description:
  Lipoate synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.


ensembl_gene_id: PYK22_02488
symbol: CDM66458.1
gene_biotype: protein_coding
description:
  NTP pyrophosphohydrolase; PFAM: NUDIX domain; TIGRFAM: nudix-type nucleoside diphosphatase, YffH/AdpP family.


ensembl_gene_id: PYK22_02489
symbol: CDM66459.1
gene_biotype: protein_coding
description:
  Folylpolyglutamate synthase/dihydrofolate synthase; PFAM: Mur ligase family, glutamate ligase domain; Mur ligase middle domain; TIGRFAM: folylpolyglutamate synthase/dihydrofolate synthase; Belongs to the folylpolyglutamate synthase family.


ensembl_gene_id: PYK22_02490
symbol: accD
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.


ensembl_gene_id: PYK22_02492
symbol: rbfA
gene_biotype: protein_coding
description:
  Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.


ensembl_gene_id: PYK22_02493
symbol: infB
gene_biotype: protein_coding
description:
  Bacterial translation initiation factor 2 (bIF-2); One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.


ensembl_gene_id: PYK22_02495
symbol: rimP
gene_biotype: protein_coding
description:
  Hypothetical protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.


ensembl_gene_id: PYK22_02496
symbol: CDM66466.1
gene_biotype: protein_coding
description:
  Sulfite dehydrogenase (cytochrome) subunit SorA apoprotein; PFAM: Mo-co oxidoreductase dimerisation domain; Oxidoreductase molybdopterin binding domain.


ensembl_gene_id: PYK22_02498
symbol: CDM66468.1
gene_biotype: protein_coding
description:
  DNA/RNA helicase, superfamily II; PFAM: Helicase conserved C-terminal domain; Type III restriction enzyme, res subunit.


ensembl_gene_id: PYK22_02501
symbol: CDM66471.1
gene_biotype: protein_coding
description:
  PFAM: Phosphoribosyl transferase domain; TIGRFAM: hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.


ensembl_gene_id: PYK22_02502
symbol: CDM66472.1
gene_biotype: protein_coding
description:
  Cobalamin-dependent methionine synthase I; PFAM: Methylenetetrahydrofolate reductase; Homocysteine S-methyltransferase.


ensembl_gene_id: PYK22_02507
symbol: CDM66477.1
gene_biotype: protein_coding
description:
  PFAM: Type IV pilin N-term methylation site GFxxxE; Type II secretion system (T2SS), protein G; TIGRFAM: prepilin-type N-terminal cleavage/methylation domain.


ensembl_gene_id: PYK22_02509
symbol: CDM66479.1
gene_biotype: protein_coding
description:
  Type II secretory pathway, component PulD; PFAM: Bacterial type II/III secretion system short domain; Bacterial type II and III secretion system protein.


ensembl_gene_id: PYK22_02510
symbol: CDM66480.1
gene_biotype: protein_coding
description:
  Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB; PFAM: Type II secretion system (T2SS), protein E, N-terminal domain; Type II/IV secretion system protein.


ensembl_gene_id: PYK22_02518
symbol: CDM66488.1
gene_biotype: protein_coding
description:
  Carbon dioxide concentrating mechanism/carboxysome shell protein; PFAM: Ethanolamine utilisation protein EutN/carboxysome.


ensembl_gene_id: PYK22_02522
symbol: guaB
gene_biotype: protein_coding
description:
  Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.


ensembl_gene_id: PYK22_02524
symbol: CDM66494.1
gene_biotype: protein_coding
description:
  Predicted metal-dependent hydrolase related to alanyl-tRNA synthetase HxxxH domain; PFAM: DHHA1 domain; Threonyl and Alanyl tRNA synthetase second additional domain; tRNA synthetases class II (A).


ensembl_gene_id: PYK22_02526
symbol: CDM66495.1
gene_biotype: protein_coding
description:
  PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; His Kinase A (phospho-acceptor) domain; PAS fold.


ensembl_gene_id: PYK22_02528
symbol: rph
gene_biotype: protein_coding
description:
  RNAse PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.


ensembl_gene_id: PYK22_02534
symbol: CDM66503.1
gene_biotype: protein_coding
description:
  KpsF/GutQ family protein; PFAM: CBS domain; SIS domain; TIGRFAM: KpsF/GutQ family protein; Belongs to the SIS family. GutQ/KpsF subfamily.


ensembl_gene_id: PYK22_02536
symbol: CDM66505.1
gene_biotype: protein_coding
description:
  Phosphatidylglycerophosphate synthase; PFAM: CDP-alcohol phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: PYK22_02540
symbol: ctaB
gene_biotype: protein_coding
description:
  Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.


ensembl_gene_id: PYK22_02543
symbol: CDM66512.1
gene_biotype: protein_coding
description:
  Cytochrome c oxidase, subunit I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.


ensembl_gene_id: PYK22_02544
symbol: CDM66513.1
gene_biotype: protein_coding
description:
  Cytochrome c oxidase, subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).


ensembl_gene_id: PYK22_02545
symbol: CDM66514.1
gene_biotype: protein_coding
description:
  Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems.


ensembl_gene_id: PYK22_02554
symbol: rsmI
gene_biotype: protein_coding
description:
  Probable S-adenosylmethionine-dependent methyltransferase, YraL family; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.


ensembl_gene_id: PYK22_02559
symbol: nadE
gene_biotype: protein_coding
description:
  NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.


ensembl_gene_id: PYK22_02560
symbol: CDM66529.1
gene_biotype: protein_coding
description:
  tRNA s(2)C-32 sulfurtransferase; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system. Belongs to the TtcA family.


ensembl_gene_id: PYK22_02562
symbol: CDM66531.1
gene_biotype: protein_coding
description:
  Lactate dehydrogenase-like oxidoreductase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain.


ensembl_gene_id: PYK22_02571
symbol: purE
gene_biotype: protein_coding
description:
  5-(carboxyamino)imidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).


ensembl_gene_id: PYK22_02572
symbol: purK
gene_biotype: protein_coding
description:
  5-(carboxyamino)imidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).


ensembl_gene_id: PYK22_02578
symbol: CDM66547.1
gene_biotype: protein_coding
description:
  Mercuric reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: mercuric reductase.


ensembl_gene_id: PYK22_02580
symbol: selA
gene_biotype: protein_coding
description:
  L-seryl-tRNA(Sec) selenium transferase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.


ensembl_gene_id: PYK22_02587
symbol: CDM66556.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; PFAM: Uncharacterised protein family (UPF0104); TIGRFAM: conserved hypothetical protein.


ensembl_gene_id: PYK22_02588
symbol: nrdR
gene_biotype: protein_coding
description:
  Transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.


ensembl_gene_id: PYK22_02589
symbol: lon
gene_biotype: protein_coding
description:
  ATP-dependent proteinase; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.


ensembl_gene_id: PYK22_02591
symbol: CDM66560.1
gene_biotype: protein_coding
description:
  Mg chelatase-related protein; PFAM: Magnesium chelatase, subunit ChlI; Subunit ChlI of Mg-chelatase; TIGRFAM: Mg chelatase-related protein.


ensembl_gene_id: PYK22_02599
symbol: rpsU
gene_biotype: protein_coding
description:
  PFAM: Ribosomal protein S21; TIGRFAM: ribosomal protein S21; Belongs to the bacterial ribosomal protein bS21 family.


ensembl_gene_id: PYK22_02604
symbol: CDM66572.1
gene_biotype: protein_coding
description:
  PFAM: Bacterial regulatory protein, Fis family; Sigma-54 interaction domain; Tetratricopeptide repeat.


ensembl_gene_id: PYK22_02605
symbol: CDM66573.1
gene_biotype: protein_coding
description:
  Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains; PFAM: zinc-ribbon domain; TIGRFAM: MJ0042 family finger-like domain.


ensembl_gene_id: PYK22_02607
symbol: dacA
gene_biotype: protein_coding
description:
  TIGR00159 family protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.


ensembl_gene_id: PYK22_02609
symbol: glmM
gene_biotype: protein_coding
description:
  Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.


ensembl_gene_id: PYK22_02610
symbol: CDM66578.1
gene_biotype: protein_coding
description:
  Nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; TIGRFAM: nucleotide sugar dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.


ensembl_gene_id: PYK22_02612
symbol: CDM66580.1
gene_biotype: protein_coding
description:
  PFAM: UDP-N-acetylglucosamine 2-epimerase; TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family.


ensembl_gene_id: PYK22_02615
symbol: CDM66583.1
gene_biotype: protein_coding
description:
  Membrane protein involved in the export of O-antigen and teichoic acid; PFAM: Polysaccharide biosynthesis C-terminal domain; Polysaccharide biosynthesis protein.


ensembl_gene_id: PYK22_02624
symbol: CDM66592.1
gene_biotype: protein_coding
description:
  Phospholipid-binding protein, PBP family; PFAM: Phosphatidylethanolamine-binding protein; TIGRFAM: Raf kinase inhibitor-like protein, YbhB/YbcL family.


ensembl_gene_id: PYK22_02631
symbol: CDM66599.1
gene_biotype: protein_coding
description:
  Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; PFAM: Bacterial sugar transferase; CoA-binding domain; TIGRFAM: Undecaprenyl-phosphate glucose phosphotransferase; Undecaprenyl-phosphate galactose phosphotransferase, WbaP; exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase.


ensembl_gene_id: PYK22_02639
symbol: CDM66607.1
gene_biotype: protein_coding
description:
  Fe-S cluster protector protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.


ensembl_gene_id: PYK22_02640
symbol: thyX
gene_biotype: protein_coding
description:
  Thymidylate synthase (FAD); Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.


ensembl_gene_id: PYK22_02641
symbol: CDM66609.1
gene_biotype: protein_coding
description:
  Pyruvate formate lyase activating protein-like uncharacterized Fe-S protein; PFAM: Radical SAM superfamily.


ensembl_gene_id: PYK22_02649
symbol: CDM66617.1
gene_biotype: protein_coding
description:
  PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phospho-acceptor) domain; PAS fold.


ensembl_gene_id: PYK22_02652
symbol: mobA
gene_biotype: protein_coding
description:
  Molybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.


ensembl_gene_id: PYK22_02654
symbol: speE
gene_biotype: protein_coding
description:
  Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine; Belongs to the spermidine/spermine synthase family.


ensembl_gene_id: PYK22_02655
symbol: speH
gene_biotype: protein_coding
description:
  Adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.


ensembl_gene_id: PYK22_02657
symbol: lpxB
gene_biotype: protein_coding
description:
  lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: PYK22_02661
symbol: CDM66629.1
gene_biotype: protein_coding
description:
  Signal transduction histidine kinase, nitrogen specific; PFAM: His Kinase A (phospho-acceptor) domain.


ensembl_gene_id: PYK22_02663
symbol: CDM66630.1
gene_biotype: protein_coding
description:
  Arginine decarboxylase; Catalyzes the biosynthesis of agmatine from arginine. Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.


ensembl_gene_id: PYK22_02666
symbol: CDM66633.1
gene_biotype: protein_coding
description:
  Tfp pilus assembly protein PilF; PFAM: Peptidase MA superfamily; Tetratricopeptide repeat; TPR repeat.


ensembl_gene_id: PYK22_02667
symbol: dxr
gene_biotype: protein_coding
description:
  1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family.


ensembl_gene_id: PYK22_02668
symbol: CDM66635.1
gene_biotype: protein_coding
description:
  RIP metalloprotease RseP; PFAM: Peptidase family M50; PDZ domain; TIGRFAM: RIP metalloprotease RseP.


ensembl_gene_id: PYK22_02669
symbol: ispG
gene_biotype: protein_coding
description:
  4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family.


ensembl_gene_id: PYK22_02671
symbol: CDM66638.1
gene_biotype: protein_coding
description:
  Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family; PFAM: XdhC Rossmann domain; XdhC and CoxI family.


ensembl_gene_id: PYK22_02686
symbol: CDM66653.1
gene_biotype: protein_coding
description:
  DNA primase; PFAM: Toprim domain; DNA primase catalytic core, N-terminal domain; CHC2 zinc finger; TIGRFAM: DNA primase, catalytic core.


ensembl_gene_id: PYK22_02687
symbol: CDM66654.1
gene_biotype: protein_coding
description:
  Serine phosphatase RsbU, regulator of sigma subunit; PFAM: GAF domain; Stage II sporulation protein E (SpoIIE).


ensembl_gene_id: PYK22_02689
symbol: deoC
gene_biotype: protein_coding
description:
  Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.


ensembl_gene_id: PYK22_02694
symbol: CDM66661.1
gene_biotype: protein_coding
description:
  Hypothetical protein; PFAM: Carboxymuconolactone decarboxylase family; TIGRFAM: alkylhydroperoxidase AhpD family core domain.


ensembl_gene_id: PYK22_02699
symbol: recG
gene_biotype: protein_coding
description:
  ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily.


ensembl_gene_id: PYK22_02700
symbol: CDM66667.1
gene_biotype: protein_coding
description:
  PFAM: Disulphide isomerase; TIGRFAM: bacillithiol system oxidoreductase, YphP/YqiW family; Belongs to the UPF0403 family.


ensembl_gene_id: PYK22_02703
symbol: lexA
gene_biotype: protein_coding
description:
  SOS regulatory protein LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.


ensembl_gene_id: PYK22_02710
symbol: CDM66677.1
gene_biotype: protein_coding
description:
  PAS domain S-box; PFAM: HAMP domain; Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; His Kinase A (phospho-acceptor) domain; PAS fold; TIGRFAM: PAS domain S-box.


ensembl_gene_id: PYK22_02729
symbol: tatC
gene_biotype: protein_coding
description:
  Twin arginine targeting protein translocase subunit TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes.


ensembl_gene_id: PYK22_02743
symbol: CDM66710.1
gene_biotype: protein_coding
description:
  PFAM: Molybdopterin-binding domain of aldehyde dehydrogenase; Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain.


ensembl_gene_id: PYK22_02766
symbol: thiL
gene_biotype: protein_coding
description:
  Thiamine-phosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.


ensembl_gene_id: PYK22_02768
symbol: cysS
gene_biotype: protein_coding
description:
  PFAM: tRNA synthetases class I (C) catalytic domain; DALR domain; TIGRFAM: cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: PYK22_02771
symbol: CDM66738.1
gene_biotype: protein_coding
description:
  PFAM: Aminotransferase class-III; TIGRFAM: 4-aminobutyrate aminotransferase, prokaryotic type; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: PYK22_02778
symbol: CDM66745.1
gene_biotype: protein_coding
description:
  DNA-binding ferritin-like protein (oxidative damage protectant); PFAM: Ferritin-like domain; Belongs to the Dps family.


ensembl_gene_id: PYK22_02779
symbol: mntH
gene_biotype: protein_coding
description:
  Natural resistance-associated macrophage protein metal ion transporter NRAMP; H(+)-stimulated, divalent metal cation uptake system. Belongs to the NRAMP family.


ensembl_gene_id: PYK22_02780
symbol: CDM66747.1
gene_biotype: protein_coding
description:
  PFAM: FeoA domain; Iron dependent repressor, metal binding and dimerisation domain; Iron dependent repressor, N-terminal DNA binding domain.


ensembl_gene_id: PYK22_02783
symbol: sucC
gene_biotype: protein_coding
description:
  succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.


ensembl_gene_id: PYK22_02785
symbol: CDM66751.1
gene_biotype: protein_coding
description:
  Predicted exonuclease of the beta-lactamase fold involved in RNA processing; PFAM: Metallo-beta-lactamase superfamily; RNA-metabolising metallo-beta-lactamase; Beta-Casp domain.


ensembl_gene_id: PYK22_02788
symbol: sucD
gene_biotype: protein_coding
description:
  succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.


ensembl_gene_id: PYK22_02789
symbol: ndk
gene_biotype: protein_coding
description:
  Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.


ensembl_gene_id: PYK22_02790
symbol: nuoI
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: PYK22_02791
symbol: CDM66757.1
gene_biotype: protein_coding
description:
  PFAM: Haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED.


ensembl_gene_id: PYK22_02798
symbol: hppA
gene_biotype: protein_coding
description:
  Vacuolar-type H(+)-translocating pyrophosphatase; Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane. Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.


ensembl_gene_id: PYK22_02799
symbol: hppA-2
gene_biotype: protein_coding
description:
  Inorganic pyrophosphatase; Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.


ensembl_gene_id: PYK22_02803
symbol: gltX
gene_biotype: protein_coding
description:
  glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.


ensembl_gene_id: PYK22_02808
symbol: dnaX
gene_biotype: protein_coding
description:
  DNA polymerase III, tau subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.


ensembl_gene_id: PYK22_02812
symbol: tadA
gene_biotype: protein_coding
description:
  tRNA-adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.


ensembl_gene_id: PYK22_02817
symbol: CDM66779.1
gene_biotype: protein_coding
description:
  AmmeMemoRadiSam system protein B; PFAM: Catalytic LigB subunit of aromatic ring-opening dioxygenase; TIGRFAM: AmmeMemoRadiSam system protein B.


ensembl_gene_id: PYK22_02819
symbol: gyrB
gene_biotype: protein_coding
description:
  DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.


ensembl_gene_id: PYK22_02820
symbol: recF
gene_biotype: protein_coding
description:
  DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family.


ensembl_gene_id: PYK22_02821
symbol: CDM66783.1
gene_biotype: protein_coding
description:
  DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]


ensembl_gene_id: PYK22_02822
symbol: dnaA
gene_biotype: protein_coding
description:
  Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.


ensembl_gene_id: PYK22_02823
symbol: rnpA
gene_biotype: protein_coding
description:
  Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.


ensembl_gene_id: PYK22_02824
symbol: yidC
gene_biotype: protein_coding
description:
  Membrane protein insertase, YidC/Oxa1 family, N-terminal domain; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.


ensembl_gene_id: PYK22_02826
symbol: mnmE
gene_biotype: protein_coding
description:
  tRNA modification GTPase trmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.


ensembl_gene_id: PYK22_02827
symbol: mnmG
gene_biotype: protein_coding
description:
  Glucose-inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family.


ensembl_gene_id: PYK22_02829
symbol: CDM66791.1
gene_biotype: protein_coding
description:
  Chromosome segregation DNA-binding protein; PFAM: ParB-like nuclease domain; KorB domain; TIGRFAM: ParB/RepB/Spo0J family partition protein; Belongs to the ParB family.


ensembl_gene_id: PYK22_02831
symbol: atpF
gene_biotype: protein_coding
description:
  F0F1-type ATP synthase, beta subunit; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family.


ensembl_gene_id: PYK22_02833
symbol: atpH
gene_biotype: protein_coding
description:
  ATP synthase, F1 delta subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.


ensembl_gene_id: PYK22_02834
symbol: atpA
gene_biotype: protein_coding
description:
  ATP synthase F1 subcomplex alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.


ensembl_gene_id: PYK22_02835
symbol: atpG
gene_biotype: protein_coding
description:
  ATP synthase F1 subcomplex gamma subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.


ensembl_gene_id: PYK22_02840
symbol: CDM66802.1
gene_biotype: protein_coding
description:
  Uncharacterized LmbE-like protein; PFAM: NPCBM-associated, NEW3 domain of alpha-galactosidase; GlcNAc-PI de-N-acetylase.


ensembl_gene_id: PYK22_02843
symbol: CDM66805.1
gene_biotype: protein_coding
description:
  PAS domain S-box; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; His Kinase A (phospho-acceptor) domain; PAS domain; TIGRFAM: PAS domain S-box.


ensembl_gene_id: PYK22_02844
symbol: CDM66806.1
gene_biotype: protein_coding
description:
  Dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: dihydrolipoamide dehydrogenase.


ensembl_gene_id: PYK22_02845
symbol: CDM66807.1
gene_biotype: protein_coding
description:
  Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase component alpha subunit; PFAM: Dehydrogenase E1 component.


ensembl_gene_id: PYK22_02847
symbol: CDM66809.1
gene_biotype: protein_coding
description:
  Branched-chain alpha-keto acid dehydrogenase E1 component; PFAM: Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain.


ensembl_gene_id: PYK22_02848
symbol: CDM66810.1
gene_biotype: protein_coding
description:
  2-oxoglutarate dehydrogenase E2 component; PFAM: 2-oxoacid dehydrogenases acyltransferase (catalytic domain); e3 binding domain; Biotin-requiring enzyme; TIGRFAM: 2-oxoglutarate dehydrogenase complex dihydrolipoamide succinyltransferase (E2 component); 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase.


ensembl_gene_id: PYK22_02854
symbol: glnD
gene_biotype: protein_coding
description:
  UTP--GlnB (protein PII) uridylyltransferase, GlnD; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.


ensembl_gene_id: PYK22_02857
symbol: CDM66819.1
gene_biotype: protein_coding
description:
  Carboxypeptidase Ss1; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain; TIGRFAM: amidohydrolase.


ensembl_gene_id: PYK22_02863
symbol: CDM66825.1
gene_biotype: protein_coding
description:
  PFAM: D-Ala-D-Ala carboxypeptidase 3 (S13) family; TIGRFAM: D-alanyl-D-alanine carboxypeptidase, serine-type, PBP4 family.


ensembl_gene_id: PYK22_02864
symbol: CDM66826.1
gene_biotype: protein_coding
description:
  D-heptose-7-phosphate 1-kinase; PFAM: pfkB family carbohydrate kinase; TIGRFAM: rfaE bifunctional protein, domain I.


ensembl_gene_id: PYK22_02865
symbol: CDM66827.1
gene_biotype: protein_coding
description:
  PFAM: Glycosyltransferase family 9 (heptosyltransferase); TIGRFAM: lipopolysaccharide heptosyltransferase III, putative; lipopolysaccharide heptosyltransferase II.


ensembl_gene_id: PYK22_02870
symbol: uvrC
gene_biotype: protein_coding
description:
  Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.


ensembl_gene_id: PYK22_02883
symbol: pyrD
gene_biotype: protein_coding
description:
  Dihydroorotate oxidase A; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.


ensembl_gene_id: PYK22_02895
symbol: CDM66856.1
gene_biotype: protein_coding
description:
  PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phospho-acceptor) domain; TIGRFAM: putative PEP-CTERM system histidine kinase.


ensembl_gene_id: PYK22_02896
symbol: CDM66857.1
gene_biotype: protein_coding
description:
  3'-phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase; PFAM: Inositol monophosphatase family; TIGRFAM: 3'(2'),5'-bisphosphate nucleotidase, bacterial.


ensembl_gene_id: PYK22_02905
symbol: CDM66866.1
gene_biotype: protein_coding
description:
  Phosphatidylglycerophosphate synthase; PFAM: CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: PYK22_02906
symbol: greA
gene_biotype: protein_coding
description:
  Transcription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.


ensembl_gene_id: PYK22_02907
symbol: pfkA
gene_biotype: protein_coding
description:
  6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.


ensembl_gene_id: PYK22_02911
symbol: CDM66872.1
gene_biotype: protein_coding
description:
  Transcriptional regulator, TetR family; PFAM: YsiA-like protein, C-terminal region; Bacterial regulatory proteins, tetR family.


ensembl_gene_id: PYK22_02913
symbol: CDM66873.1
gene_biotype: protein_coding
description:
  Kef-type potassium/proton antiporter, CPA2 family (TC 2.A.37.1); PFAM: TrkA-N domain; TrkA-C domain; Sodium/hydrogen exchanger family; TIGRFAM: transporter, monovalent cation:proton antiporter-2 (CPA2) family.


ensembl_gene_id: PYK22_02918
symbol: mnmA
gene_biotype: protein_coding
description:
  tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.


ensembl_gene_id: PYK22_02919
symbol: CDM66879.1
gene_biotype: protein_coding
description:
  PFAM: Peptidase family S49; TIGRFAM: signal peptide peptidase SppA, 36K type; signal peptide peptidase SppA, 67K type.


ensembl_gene_id: PYK22_02920
symbol: serS
gene_biotype: protein_coding
description:
  seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).


ensembl_gene_id: PYK22_02921
symbol: CDM66881.1
gene_biotype: protein_coding
description:
  UDP-glucose pyrophosphorylase; PFAM: Nucleotidyl transferase; TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase.


ensembl_gene_id: PYK22_02922
symbol: CDM66882.1
gene_biotype: protein_coding
description:
  3-oxoacyl-(acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: PYK22_02927
symbol: aroK
gene_biotype: protein_coding
description:
  Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.


ensembl_gene_id: PYK22_02928
symbol: aroA
gene_biotype: protein_coding
description:
  3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.


ensembl_gene_id: PYK22_02930
symbol: CDM66889.1
gene_biotype: protein_coding
description:
  PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor; Belongs to the anti-sigma-factor antagonist family.


ensembl_gene_id: PYK22_02933
symbol: CDM66892.1
gene_biotype: protein_coding
description:
  PFAM: Cobalamin adenosyltransferase; TIGRFAM: ATP:cob(I)alamin adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family.


ensembl_gene_id: PYK22_02936
symbol: CDM66895.1
gene_biotype: protein_coding
description:
  enoyl-CoA hydratase/carnithine racemase; PFAM: Enoyl-CoA hydratase/isomerase family; TIGRFAM: cyclohexa-1,5-dienecarbonyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: PYK22_02939
symbol: CDM66898.1
gene_biotype: protein_coding
description:
  Serine phosphatase RsbU, regulator of sigma subunit; PFAM: GAF domain; Stage II sporulation protein E (SpoIIE); FHA domain.


ensembl_gene_id: PYK22_02945
symbol: macB
gene_biotype: protein_coding
description:
  ABC-type antimicrobial peptide transport system, ATPase component; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.


ensembl_gene_id: PYK22_02946
symbol: CDM66905.1
gene_biotype: protein_coding
description:
  ABC-type antimicrobial peptide transport system, permease component; PFAM: MacB-like periplasmic core domain; FtsX-like permease family.


ensembl_gene_id: PYK22_02955
symbol: atpD
gene_biotype: protein_coding
description:
  ATP synthase F1 subcomplex beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.


ensembl_gene_id: PYK22_02956
symbol: atpC
gene_biotype: protein_coding
description:
  ATP synthase, F1 epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane.


ensembl_gene_id: PYK22_02957
symbol: pdxJ
gene_biotype: protein_coding
description:
  Pyridoxine 5'-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.


ensembl_gene_id: PYK22_02959
symbol: CDM66918.1
gene_biotype: protein_coding
description:
  C-terminal processing peptidase; PFAM: Peptidase family S41; PDZ domain (Also known as DHR or GLGF); TIGRFAM: C-terminal peptidase (prc); Belongs to the peptidase S41A family.


ensembl_gene_id: PYK22_02969
symbol: CDM66926.1
gene_biotype: protein_coding
description:
  NADPH-dependent glutamate synthase beta chain-like oxidoreductase; PFAM: Oxidoreductase NAD-binding domain.


ensembl_gene_id: PYK22_02971
symbol: CDM66928.1
gene_biotype: protein_coding
description:
  ABC-type uncharacterized transport system, permease component; PFAM: High-affinity nickel-transport protein; Belongs to the NiCoT transporter (TC 2.A.52) family.


ensembl_gene_id: PYK22_02974
symbol: CDM66931.1
gene_biotype: protein_coding
description:
  Nicotinic acid phosphoribosyltransferase; PFAM: Nicotinate phosphoribosyltransferase (NAPRTase) family; TIGRFAM: putative nicotinate phosphoribosyltransferase; Belongs to the NAPRTase family.


ensembl_gene_id: PYK22_02981
symbol: CDM66936.1
gene_biotype: protein_coding
description:
  Gamma-glutamyltransferase; PFAM: Gamma-glutamyltranspeptidase; TIGRFAM: gamma-glutamyltranspeptidase.


ensembl_gene_id: PYK22_02984
symbol: clpX
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.


ensembl_gene_id: PYK22_02985
symbol: clpP
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.


ensembl_gene_id: PYK22_02986
symbol: tig
gene_biotype: protein_coding
description:
  Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.


ensembl_gene_id: PYK22_02992
symbol: CDM66945.1
gene_biotype: protein_coding
description:
  5'-nucleotidase/2',3'-cyclic phosphodiesterase-like hydrolase; PFAM: 5'-nucleotidase, C-terminal domain; Calcineurin-like phosphoesterase; Belongs to the 5'-nucleotidase family.


ensembl_gene_id: PYK22_02997
symbol: CDM66950.1
gene_biotype: protein_coding
description:
  Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit; PFAM: Dehydrogenase E1 component; Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain.


ensembl_gene_id: PYK22_03001
symbol: ileS
gene_biotype: protein_coding
description:
  Isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.


ensembl_gene_id: PYK22_03002
symbol: lspA
gene_biotype: protein_coding
description:
  Signal peptidase II; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.


ensembl_gene_id: PYK22_03003
symbol: lgt
gene_biotype: protein_coding
description:
  Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.


ensembl_gene_id: PYK22_03004
symbol: CDM66957.1
gene_biotype: protein_coding
description:
  Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.


ensembl_gene_id: PYK22_03005
symbol: CDM66958.1
gene_biotype: protein_coding
description:
  Predicted kinase; PFAM: Calcineurin-like phosphoesterase; AAA domain; TIGRFAM: polynucleotide kinase-phosphatase.


ensembl_gene_id: PYK22_03008
symbol: kynA
gene_biotype: protein_coding
description:
  Tryptophan 2,3-dioxygenase (vermilion); Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.


ensembl_gene_id: PYK22_03015
symbol: topA
gene_biotype: protein_coding
description:
  DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]


ensembl_gene_id: PYK22_03020
symbol: atpB
gene_biotype: protein_coding
description:
  F0F1-type ATP synthase, alpha subunit; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family.


ensembl_gene_id: PYK22_03021
symbol: atpE
gene_biotype: protein_coding
description:
  F0F1-type ATP synthase, subunit c/archaeal/vacuolar-type H+-ATPase, subunit K; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.


ensembl_gene_id: PYK22_03027
symbol: CDM66979.1
gene_biotype: protein_coding
description:
  Phosphotransacetylase; PFAM: Phosphate acetyl/butaryl transferase; TIGRFAM: phosphate acetyltransferase.


ensembl_gene_id: PYK22_03042
symbol: CDM66993.1
gene_biotype: protein_coding
description:
  Farnesyl-diphosphate synthase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.


ensembl_gene_id: PYK22_03043
symbol: xseB
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.


ensembl_gene_id: PYK22_03044
symbol: xseA
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family.


ensembl_gene_id: PYK22_03046
symbol: alaS
gene_biotype: protein_coding
description:
  alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.


ensembl_gene_id: PYK22_03056
symbol: murA
gene_biotype: protein_coding
description:
  UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.


ensembl_gene_id: PYK22_03057
symbol: prmC
gene_biotype: protein_coding
description:
  protein-(glutamine-N5) methyltransferase, release factor-specific; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.


ensembl_gene_id: PYK22_03059
symbol: CDM67010.1
gene_biotype: protein_coding
description:
  Serine O-acetyltransferase; PFAM: Bacterial transferase hexapeptide (six repeats); TIGRFAM: serine O-acetyltransferase.


ensembl_gene_id: PYK22_03060
symbol: CDM67011.1
gene_biotype: protein_coding
description:
  PFAM: NADH ubiquinone oxidoreductase, 20 Kd subunit; NiFe/NiFeSe hydrogenase small subunit C-terminal; TIGRFAM: hydrogenase (NiFe) small subunit (hydA).


ensembl_gene_id: PYK22_03061
symbol: CDM67012.1
gene_biotype: protein_coding
description:
  PAS domain S-box; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; PAS domain; PAS fold; TIGRFAM: PAS domain S-box.


ensembl_gene_id: PYK22_03074
symbol: hypA
gene_biotype: protein_coding
description:
  Zn finger protein HypA/HybF (possibly regulating hydrogenase expression); Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.


ensembl_gene_id: PYK22_03075
symbol: CDM67026.1
gene_biotype: protein_coding
description:
  Hydrogenase accessory protein HypB; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB.


ensembl_gene_id: PYK22_03078
symbol: CDM67029.1
gene_biotype: protein_coding
description:
  Hydrogenase maturation protein HypD; PFAM: Hydrogenase formation hypA family; TIGRFAM: hydrogenase expression/formation protein HypD.


ensembl_gene_id: PYK22_03079
symbol: CDM67030.1
gene_biotype: protein_coding
description:
  Hydrogenase maturation protein, carbamoyl dehydratase HypE; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: hydrogenase expression/formation protein HypE.


ensembl_gene_id: PYK22_03082
symbol: CDM67033.1
gene_biotype: protein_coding
description:
  PFAM: HypF finger; Acylphosphatase; Telomere recombination; TIGRFAM: [NiFe] hydrogenase maturation protein HypF.


ensembl_gene_id: PYK22_03083
symbol: CDM67034.1
gene_biotype: protein_coding
description:
  Glutamate synthase (NADH) large subunit; PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II.


ensembl_gene_id: PYK22_03084
symbol: CDM67035.1
gene_biotype: protein_coding
description:
  Glutamate synthase (NADH) small subunit; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster; TIGRFAM: glutamate synthases, NADH/NADPH, small subunit.


ensembl_gene_id: PYK22_03089
symbol: truB
gene_biotype: protein_coding
description:
  tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.


ensembl_gene_id: PYK22_03091
symbol: CDM67042.1
gene_biotype: protein_coding
description:
  Sporulation protein YhbH; PFAM: Protein of unknown function (DUF444); TIGRFAM: sporulation protein YhbH; Belongs to the UPF0229 family.


ensembl_gene_id: PYK22_03094
symbol: mutL
gene_biotype: protein_coding
description:
  DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.


ensembl_gene_id: PYK22_03095
symbol: bshC
gene_biotype: protein_coding
description:
  Bacillithiol biosynthesis cysteine-adding enzyme BshC; PFAM: Uncharacterized protein conserved in bacteria (DUF2317); TIGRFAM: bacillithiol biosynthesis cysteine-adding enzyme BshC; Belongs to the BshC family.


ensembl_gene_id: PYK22_03096
symbol: CDM67047.1
gene_biotype: protein_coding
description:
  Thioredoxin reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: putative bacillithiol system oxidoreductase, YpdA family.


ensembl_gene_id: PYK22_03098
symbol: CDM67049.1
gene_biotype: protein_coding
description:
  Predicted oxidoreductase, aryl-alcohol dehydrogenase like protein; PFAM: Aldo/keto reductase family; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence.


ensembl_gene_id: PYK22_03100
symbol: ackA
gene_biotype: protein_coding
description:
  Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.


ensembl_gene_id: PYK22_03109
symbol: CDM67060.1
gene_biotype: protein_coding
description:
  Thermostable 8-oxoguanine DNA glycosylase; PFAM: HhH-GPD superfamily base excision DNA repair protein.


ensembl_gene_id: PYK22_03112
symbol: lysA
gene_biotype: protein_coding
description:
  Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.


ensembl_gene_id: PYK22_03121
symbol: CDM67072.1
gene_biotype: protein_coding
description:
  Beta-propeller domain-containing protein, methanol dehydrogenase; PFAM: TLP18.3, Psb32 and MOLO-1 founding proteins of phosphatase.


ensembl_gene_id: PYK22_03124
symbol: rsmH
gene_biotype: protein_coding
description:
  16S rRNA (cytosine(1402)-N(4))-methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.


ensembl_gene_id: PYK22_03126
symbol: CDM67077.1
gene_biotype: protein_coding
description:
  Peptidoglycan synthetase FtsI; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain; PASTA domain.


ensembl_gene_id: PYK22_03128
symbol: murF
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.


ensembl_gene_id: PYK22_03129
symbol: mraY
gene_biotype: protein_coding
description:
  Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.


ensembl_gene_id: PYK22_03130
symbol: murD
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.


ensembl_gene_id: PYK22_03132
symbol: murG
gene_biotype: protein_coding
description:
  UDP-N-acetylglucosamine-N- acetylmuramylpentapeptide N-acetylglucosamine transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.


ensembl_gene_id: PYK22_03135
symbol: ftsA
gene_biotype: protein_coding
description:
  Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.


ensembl_gene_id: PYK22_03136
symbol: ftsZ
gene_biotype: protein_coding
description:
  Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.


ensembl_gene_id: PYK22_03138
symbol: CDM67089.1
gene_biotype: protein_coding
description:
  4-hydroxythreonine-4-phosphate dehydrogenase; PFAM: Pyridoxal phosphate biosynthetic protein PdxA; TIGRFAM: 4-hydroxythreonine-4-phosphate dehydrogenase; Belongs to the PdxA family.


ensembl_gene_id: PYK22_03141
symbol: nfi
gene_biotype: protein_coding
description:
  Endonuclease V; DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.


ensembl_gene_id: PYK22_03142
symbol: lon-3
gene_biotype: protein_coding
description:
  ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.


ensembl_gene_id: PYK22_03146
symbol: CDM67097.1
gene_biotype: protein_coding
description:
  Ferredoxin subunit of nitrite reductase and ring-hydroxylating dioxygenase; PFAM: Rieske [2Fe-2S] domain; TIGRFAM: nitrite reductase [NAD(P)H], small subunit.


ensembl_gene_id: PYK22_03148
symbol: nadA
gene_biotype: protein_coding
description:
  Quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.


ensembl_gene_id: PYK22_03149
symbol: fumC
gene_biotype: protein_coding
description:
  Fumarase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.


ensembl_gene_id: PYK22_03151
symbol: purL
gene_biotype: protein_coding
description:
  Phosphoribosylformylglycinamidine synthase subunit II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to [...]


ensembl_gene_id: PYK22_03155
symbol: purQ
gene_biotype: protein_coding
description:
  Phosphoribosylformylglycinamidine synthase subunit I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to  [...]


ensembl_gene_id: PYK22_03156
symbol: purS
gene_biotype: protein_coding
description:
  Phosphoribosylformylglycinamidine synthase, purS protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...]


ensembl_gene_id: PYK22_03158
symbol: CDM67109.1
gene_biotype: protein_coding
description:
  PFAM: Lyase; Adenylosuccinate lyase C-terminus; TIGRFAM: adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.


ensembl_gene_id: PYK22_03170
symbol: CDM67121.1
gene_biotype: protein_coding
description:
  PFAM: N-terminal domain of ribose phosphate pyrophosphokinase; Phosphoribosyl synthetase-associated domain; TIGRFAM: ribose-phosphate pyrophosphokinase.


ensembl_gene_id: PYK22_03179
symbol: CDM67130.1
gene_biotype: protein_coding
description:
  PFAM: Glycosyl hydrolase family 3 C-terminal domain; Glycosyl hydrolase family 3 N terminal domain; Fibronectin type III-like domain.


ensembl_gene_id: PYK22_03180
symbol: CDM67131.1
gene_biotype: protein_coding
description:
  Beta-galactosidase/beta-glucuronidase; PFAM: Glycosyl hydrolases family 2, TIM barrel domain; Glycosyl hydrolases family 2; Glycosyl hydrolases family 2, sugar binding domain.


ensembl_gene_id: PYK22_03181
symbol: CDM67132.1
gene_biotype: protein_coding
description:
  Endoglucanase; PFAM: Cellulase (glycosyl hydrolase family 5); Belongs to the glycosyl hydrolase 5 (cellulase A) family.


ensembl_gene_id: PYK22_03189
symbol: CDM67140.1
gene_biotype: protein_coding
description:
  PFAM: SpoU rRNA Methylase family; RNA 2'-O ribose methyltransferase substrate binding; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.


ensembl_gene_id: PYK22_03191
symbol: thrB
gene_biotype: protein_coding
description:
  Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.


ensembl_gene_id: PYK22_03192
symbol: proC
gene_biotype: protein_coding
description:
  Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.


ensembl_gene_id: PYK22_03193
symbol: CDM67144.1
gene_biotype: protein_coding
description:
  L-threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.


ensembl_gene_id: PYK22_03194
symbol: CDM67145.1
gene_biotype: protein_coding
description:
  Aspartate kinase; PFAM: ACT domain; Amino acid kinase family; TIGRFAM: aspartate kinase, monofunctional class; aspartate kinase; Belongs to the aspartokinase family.


ensembl_gene_id: PYK22_03201
symbol: CDM67152.1
gene_biotype: protein_coding
description:
  CRISPR-associated endoribonuclease Cas6; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).


ensembl_gene_id: PYK22_03205
symbol: CDM67156.1
gene_biotype: protein_coding
description:
  PFAM: CRISPR-associated protein (Cas_Cmr3); TIGRFAM: CRISPR type III-B/RAMP module-associated protein Cmr3.


ensembl_gene_id: PYK22_03207
symbol: CDM67158.1
gene_biotype: protein_coding
description:
  PFAM: CRISPR-associated protein (Cas_Cmr5); TIGRFAM: CRISPR type III-B/RAMP module-associated protein Cmr5.


ensembl_gene_id: PYK22_03210
symbol: CDM67161.1
gene_biotype: protein_coding
description:
  PFAM: CRISPR-associated (Cas) DxTHG family; CRISPR-associated protein (Cas_csx3); TIGRFAM: CRISPR-associated protein, TM1812 family.


ensembl_gene_id: PYK22_03213
symbol: CDM67164.1
gene_biotype: protein_coding
description:
  PFAM: CRISPR-associated protein TM1802 (cas_TM1802); TIGRFAM: CRISPR-associated protein Cas8b/Csh1, subtype I-B/HMARI.


ensembl_gene_id: PYK22_03214
symbol: CDM67165.1
gene_biotype: protein_coding
description:
  CRISPR-associated protein Cas7/Csh2, subtype I-B/HMARI; PFAM: Family of unknown function (DUF694); TIGRFAM: CRISPR-associated protein, CT1132 family; CRISPR-associated protein Cas7/Csh2, subtype I-B/HMARI.


ensembl_gene_id: PYK22_03215
symbol: CDM67166.1
gene_biotype: protein_coding
description:
  PFAM: CRISPR-associated protein (Cas_Cas5); TIGRFAM: CRISPR-associated protein Cas5, subtype I-B/HMARI; CRISPR-associated protein Cas5, N-terminal domain.


ensembl_gene_id: PYK22_03216
symbol: CDM67167.1
gene_biotype: protein_coding
description:
  PFAM: DEAD/DEAH box helicase; TIGRFAM: CRISPR-associated helicase Cas3; CRISPR-associated endonuclease Cas3-HD.


ensembl_gene_id: PYK22_03217
symbol: CDM67168.1
gene_biotype: protein_coding
description:
  CRISPR-associated exonuclease, Cas4 family; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Belongs to the CRISPR-associated exonuclease Cas4 family.


ensembl_gene_id: PYK22_03218
symbol: cas1-2
gene_biotype: protein_coding
description:
  CRISPR-associated endonuclease Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.


ensembl_gene_id: PYK22_03219
symbol: cas2-2
gene_biotype: protein_coding
description:
  Uncharacterized protein predicted to be involved in DNA repair; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.


