# geneInfo

ensembl_gene_id: ETA_00060
symbol: kup
gene_biotype: protein_coding
description:
  Low affinity potassium transport system protein kup (Kup system potassium uptake protein); Responsible for the low-affinity transport of potassium into the cell, with the probable concomitant uptake of protons (symport system); Belongs to the HAK/KUP transporter (TC 2.A.72) family.


ensembl_gene_id: ETA_00100
symbol: budR
gene_biotype: protein_coding
description:
  HTH-type transcriptional regulator BudR (Bud operon transcriptional regulator); silverDB:etchr00010; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: ETA_00110
symbol: budA
gene_biotype: protein_coding
description:
  Acetolactate decarboxylase; silverDB:etchr00011; Belongs to the alpha-acetolactate decarboxylase family.


ensembl_gene_id: ETA_00130
symbol: rbsD
gene_biotype: protein_coding
description:
  D-ribose high-affinity transport system; Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.


ensembl_gene_id: ETA_00140
symbol: rbsA
gene_biotype: protein_coding
description:
  D-ribose high-affinity transport protein; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family.


ensembl_gene_id: ETA_00150
symbol: rbsC
gene_biotype: protein_coding
description:
  Ribose transport permease system protein; silverDB:etchr00015; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: ETA_00170
symbol: rbsK
gene_biotype: protein_coding
description:
  Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.


ensembl_gene_id: ETA_00190
symbol: mdtD
gene_biotype: protein_coding
description:
  Putative MFS family transport protein; silverDB:etchr00019; Belongs to the major facilitator superfamily.


ensembl_gene_id: ETA_00200
symbol: mobA
gene_biotype: protein_coding
description:
  Molybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family.


ensembl_gene_id: ETA_00220
symbol: yihE
gene_biotype: protein_coding
description:
  Conserved hypothetical protein YihE; A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.


ensembl_gene_id: ETA_00240
symbol: polA
gene_biotype: protein_coding
description:
  DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.


ensembl_gene_id: ETA_00250
symbol: engB
gene_biotype: protein_coding
description:
  Probable GTP-binding protein EngB; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.


ensembl_gene_id: ETA_00260
symbol: yihI
gene_biotype: protein_coding
description:
  Conserved hypothetical protein YihI; A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis. Belongs to the YihI family.


ensembl_gene_id: ETA_00270
symbol: hemN
gene_biotype: protein_coding
description:
  O2-independent coproporphyrinogen III oxidase; silverDB:etchr00027; Belongs to the anaerobic coproporphyrinogen-III oxidase family.


ensembl_gene_id: ETA_00280
symbol: ntrC
gene_biotype: protein_coding
description:
  Nitrogen assimilation regulatory protein; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.


ensembl_gene_id: ETA_00340
symbol: dtd
gene_biotype: protein_coding
description:
  D-tyrosyl-tRNA (Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family.


ensembl_gene_id: ETA_00360
symbol: rluF
gene_biotype: protein_coding
description:
  Ribosomal large subunit pseudouridine synthase F; silverDB:etchr00036; Belongs to the pseudouridine synthase RsuA family.


ensembl_gene_id: ETA_00390
symbol: recG
gene_biotype: protein_coding
description:
  ATP-dependent DNA helicase; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily.


ensembl_gene_id: ETA_00400
symbol: spoU
gene_biotype: protein_coding
description:
  Putative tRNA/rRNA methyltransferase; Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.


ensembl_gene_id: ETA_00410
symbol: spoT
gene_biotype: protein_coding
description:
  Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.


ensembl_gene_id: ETA_00420
symbol: rpoZ
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase omega chain; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.


ensembl_gene_id: ETA_00440
symbol: ligB
gene_biotype: protein_coding
description:
  Putative NAD-dependent DNA ligase; Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. Belongs to the NAD-dependent DNA ligase family. LigB subfamily.


ensembl_gene_id: ETA_00610
symbol: rph
gene_biotype: protein_coding
description:
  Ribonuclease PH (tRNA nucleotidyltransferase); Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.


ensembl_gene_id: ETA_00620
symbol: pyrE
gene_biotype: protein_coding
description:
  Orotate phosphoribosyltransferase (OPRTase); Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).


ensembl_gene_id: ETA_00630
symbol: ttk
gene_biotype: protein_coding
description:
  Putative transcriptional regulator; Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.


ensembl_gene_id: ETA_00640
symbol: dut
gene_biotype: protein_coding
description:
  Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTP pyrophosphatase); This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.


ensembl_gene_id: ETA_00650
symbol: dfp
gene_biotype: protein_coding
description:
  Flavoprotein affecting synthesis of DNA and pantothenate metabolism; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.


ensembl_gene_id: ETA_00670
symbol: rpmB
gene_biotype: protein_coding
description:
  50S ribosomal protein L28; silverDB:etchr10001; Belongs to the bacterial ribosomal protein bL28 family.


ensembl_gene_id: ETA_00680
symbol: rpmG
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L33; silverDB:etchr00067; Belongs to the bacterial ribosomal protein bL33 family.


ensembl_gene_id: ETA_00690
symbol: mutM
gene_biotype: protein_coding
description:
  Formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.


ensembl_gene_id: ETA_00700
symbol: coaD
gene_biotype: protein_coding
description:
  Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.


ensembl_gene_id: ETA_00720
symbol: kdtA
gene_biotype: protein_coding
description:
  3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.


ensembl_gene_id: ETA_00850
symbol: waaD
gene_biotype: protein_coding
description:
  ADP-L-glycero-D-manno-heptose-6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.


ensembl_gene_id: ETA_00890
symbol: grxC
gene_biotype: protein_coding
description:
  Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.


ensembl_gene_id: ETA_00900
symbol: secB
gene_biotype: protein_coding
description:
  Protein-export protein SecB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.


ensembl_gene_id: ETA_00910
symbol: gpsA
gene_biotype: protein_coding
description:
  NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; silverDB:etchr00090; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.


ensembl_gene_id: ETA_00930
symbol: cspR
gene_biotype: protein_coding
description:
  rRNA methyltransferase CspR (SpoU class); Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.


ensembl_gene_id: ETA_00970
symbol: fieF
gene_biotype: protein_coding
description:
  Cation-efflux pump FieF; silverDB:etchr00096; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.


ensembl_gene_id: ETA_00980
symbol: pfkA
gene_biotype: protein_coding
description:
  6-phosphofructokinase isozyme I; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.


ensembl_gene_id: ETA_01060
symbol: tpiA
gene_biotype: protein_coding
description:
  Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.


ensembl_gene_id: ETA_01140
symbol: glpK
gene_biotype: protein_coding
description:
  Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate.


ensembl_gene_id: ETA_01150
symbol: glpF
gene_biotype: protein_coding
description:
  Glycerol uptake facilitator protein; silverDB:etchr00114; Belongs to the MIP/aquaporin (TC 1.A.8) family.


ensembl_gene_id: ETA_01160
symbol: zapB
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA.


ensembl_gene_id: ETA_01170
symbol: rraA
gene_biotype: protein_coding
description:
  Regulator of ribonuclease activity A; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome.


ensembl_gene_id: ETA_01180
symbol: hslU
gene_biotype: protein_coding
description:
  ATP-dependent hsl protease ATP-binding subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.


ensembl_gene_id: ETA_01190
symbol: hslV
gene_biotype: protein_coding
description:
  ATP-dependent protease HslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.


ensembl_gene_id: ETA_01200
symbol: ftsN
gene_biotype: protein_coding
description:
  Cell division protein; Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases.


ensembl_gene_id: ETA_01220
symbol: priA
gene_biotype: protein_coding
description:
  Primosomal protein N', ATP-dependent helicase priA (Replication factor Y); Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.


ensembl_gene_id: ETA_01250
symbol: ETA_01250
gene_biotype: protein_coding
description:
  Regulatory protein, LysR; silverDB:etchr00124; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: ETA_01260
symbol: metJ
gene_biotype: protein_coding
description:
  Met repressor (Met regulon regulatory protein metJ); This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family.


ensembl_gene_id: ETA_01280
symbol: metL
gene_biotype: protein_coding
description:
  Bifunctional aspartokinase/homoserine dehydrogenase II (AKII-HDII); silverDB:etchr00127; In the C-terminal section; belongs to the homoserine dehydrogenase family.


ensembl_gene_id: ETA_01290
symbol: metF
gene_biotype: protein_coding
description:
  5,10 methylenetetrahydrofolate reductase; silverDB:etchr00128; Belongs to the methylenetetrahydrofolate reductase family.


ensembl_gene_id: ETA_01330
symbol: ppc
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.


ensembl_gene_id: ETA_01340
symbol: argE
gene_biotype: protein_coding
description:
  Acetylornithine deacetylase; silverDB:etchr00133; Belongs to the peptidase M20A family. ArgE subfamily.


ensembl_gene_id: ETA_01350
symbol: argB
gene_biotype: protein_coding
description:
  Acetylglutamate kinase (N-acetyl-L-glutamate 5-phosphotransferase); Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate.


ensembl_gene_id: ETA_01360
symbol: argG
gene_biotype: protein_coding
description:
  Argininosuccinate synthase; silverDB:etchr00135; Belongs to the argininosuccinate synthase family. Type 1 subfamily.


ensembl_gene_id: ETA_01390
symbol: oxyR
gene_biotype: protein_coding
description:
  Hydrogen peroxide-inducible genes activator; silverDB:etchr00138; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: ETA_01400
symbol: udhA
gene_biotype: protein_coding
description:
  Soluble pyridine nucleotide transhydrogenase; Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.


ensembl_gene_id: ETA_01410
symbol: fabR
gene_biotype: protein_coding
description:
  Putative regulatory protein, TetR (homolog YijC); Represses the transcription of fabB, involved in unsaturated fatty acid (UFA) biosynthesis. By controlling UFA production, FabR directly influences the physical properties of the membrane bilayer.


ensembl_gene_id: ETA_01430
symbol: trmA
gene_biotype: protein_coding
description:
  tRNA (uracil-5-)-methyltransferase; Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).


ensembl_gene_id: ETA_01460
symbol: birA
gene_biotype: protein_coding
description:
  Bifunctional protein: biotin operon repressor and biotin-[acetyl-CoA carboxylase] synthetase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.


ensembl_gene_id: ETA_01480
symbol: tufA
gene_biotype: protein_coding
description:
  Elongation factor Tu-A; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.


ensembl_gene_id: ETA_01490
symbol: secE
gene_biotype: protein_coding
description:
  Preprotein translocase, secE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61-gamma family.


ensembl_gene_id: ETA_01500
symbol: nusG
gene_biotype: protein_coding
description:
  Transcription antitermination protein; Participates in transcription elongation, termination and antitermination. In the absence of Rho, increases the rate of transcription elongation by the RNA polymerase (RNAP), probably by partially suppressing pausing. In the presence of Rho, modulates most Rho-dependent termination events by interacting with the RNAP to render the complex more susceptible to the termination activity of Rho. May be required to overcome a kinetic limitation of Rho to function at certain terminators. Also involved in ribosomal RNA transcriptional antitermination; Bel [...]


ensembl_gene_id: ETA_01510
symbol: rplK
gene_biotype: protein_coding
description:
  50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.


ensembl_gene_id: ETA_01520
symbol: rplA
gene_biotype: protein_coding
description:
  50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.


ensembl_gene_id: ETA_01530
symbol: rplJ
gene_biotype: protein_coding
description:
  50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.


ensembl_gene_id: ETA_01540
symbol: rplL
gene_biotype: protein_coding
description:
  50S ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family.


ensembl_gene_id: ETA_01550
symbol: rpoB
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: ETA_01560
symbol: rpoC
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase beta' chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: ETA_01670
symbol: yedX
gene_biotype: protein_coding
description:
  Putative transthyretin-like protein; silverDB:etchr00166; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.


ensembl_gene_id: ETA_01700
symbol: thiE
gene_biotype: protein_coding
description:
  Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.


ensembl_gene_id: ETA_01710
symbol: thiC
gene_biotype: protein_coding
description:
  Thiamine biosynthesis protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.


ensembl_gene_id: ETA_01720
symbol: rsd
gene_biotype: protein_coding
description:
  Regulator of sigma D, binding activity to the major sigma subunit of RNAP; Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase.


ensembl_gene_id: ETA_01740
symbol: hemE
gene_biotype: protein_coding
description:
  Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.


ensembl_gene_id: ETA_01750
symbol: nfi
gene_biotype: protein_coding
description:
  Endonuclease V (Deoxyinosine 3'endonuclease); DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.


ensembl_gene_id: ETA_01770
symbol: hupA
gene_biotype: protein_coding
description:
  DNA-binding protein HU-alpha; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.


ensembl_gene_id: ETA_01810
symbol: hdfR
gene_biotype: protein_coding
description:
  HTH-type transcriptional regulator HdfR; Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon.


ensembl_gene_id: ETA_01860
symbol: ilvE
gene_biotype: protein_coding
description:
  Branched-chain amino-acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: ETA_01880
symbol: ilvA
gene_biotype: protein_coding
description:
  Threonine deaminase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.


ensembl_gene_id: ETA_01890
symbol: ilvY
gene_biotype: protein_coding
description:
  Positive regulator for IlvC (LysR-family transcriptional regulatory protein); silverDB:etchr00188; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: ETA_01900
symbol: ilvC
gene_biotype: protein_coding
description:
  Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.


ensembl_gene_id: ETA_01920
symbol: rep
gene_biotype: protein_coding
description:
  ATP-dependent DNA helicase Rep; Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.


ensembl_gene_id: ETA_01930
symbol: gppA
gene_biotype: protein_coding
description:
  Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase; Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities.


ensembl_gene_id: ETA_01940
symbol: rhlB
gene_biotype: protein_coding
description:
  ATP-dependent RNA helicase; DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. Belongs to the DEAD box helicase family. RhlB subfamily.


ensembl_gene_id: ETA_01960
symbol: rho
gene_biotype: protein_coding
description:
  Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.


ensembl_gene_id: ETA_01970
symbol: wecA
gene_biotype: protein_coding
description:
  Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase; Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP-C55).


ensembl_gene_id: ETA_01980
symbol: wzzE
gene_biotype: protein_coding
description:
  Lipopolysaccharide biosynthesis protein WzzE; Modulates the polysaccharide chain length of enterobacterial common antigen (ECA); Belongs to the WzzB/Cld/Rol family.


ensembl_gene_id: ETA_01990
symbol: wecB
gene_biotype: protein_coding
description:
  UDP-N-acetylglucosamine 2-epimerase; Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP- N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues.


ensembl_gene_id: ETA_02000
symbol: wecC
gene_biotype: protein_coding
description:
  UDP-glucose/GDP-mannose dehydrogenase; Catalyzes the four-electron oxidation of UDP-N-acetyl-D- mannosamine (UDP-ManNAc), reducing NAD(+) and releasing UDP-N- acetylmannosaminuronic acid (UDP-ManNAcA); Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. WecC subfamily.


ensembl_gene_id: ETA_02010
symbol: rmlB
gene_biotype: protein_coding
description:
  DTDP-glucose 4,6-dehydratase; silverDB:etchr00200; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.


ensembl_gene_id: ETA_02020
symbol: rmlA
gene_biotype: protein_coding
description:
  Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.


ensembl_gene_id: ETA_02030
symbol: wecD
gene_biotype: protein_coding
description:
  Lipopolysaccharide biosynthesis protein; Catalyzes the acetylation of dTDP-fucosamine (dTDP-4-amino- 4,6-dideoxy-D-galactose) to dTDP-Fuc4NAc, which is utilized in the biosynthesis of the enterobacterial common antigen (ECA). Belongs to the WecD family.


ensembl_gene_id: ETA_02040
symbol: wecE
gene_biotype: protein_coding
description:
  Lipopolysaccharide biosynthesis protein; Catalyzes the synthesis of dTDP-4-amino-4,6-dideoxy-D- galactose (dTDP-Fuc4N) from dTDP-4-keto-6-deoxy-D-glucose (dTDP-D- Glc4O) and L-glutamate; Belongs to the DegT/DnrJ/EryC1 family.


ensembl_gene_id: ETA_02050
symbol: wzxE
gene_biotype: protein_coding
description:
  Lipopolysaccharide biosynthesis protein; Mediates the transbilayer movement of Und-PP-GlcNAc-ManNAcA- Fuc4NAc (lipid III) from the inner to the outer leaflet of the cytoplasmic membrane during the assembly of enterobacterial common antigen (ECA); Belongs to the polysaccharide transport (PST) (TC 2.A.66.2) family.


ensembl_gene_id: ETA_02060
symbol: wecF
gene_biotype: protein_coding
description:
  4-alpha-L-fucosyltransferase; Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis; Belongs to the glycosyltransferase 56 family.


ensembl_gene_id: ETA_02070
symbol: wzyE
gene_biotype: protein_coding
description:
  Putative ECA polymerase; Probably involved in the polymerization of enterobacterial common antigen (ECA) trisaccharide repeat units; Belongs to the WzyE family.


ensembl_gene_id: ETA_02080
symbol: wecG
gene_biotype: protein_coding
description:
  Probable UDP-N-acetyl-D-mannosaminuronic acid transferase; Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA (Lipid II), the second lipid-linked intermediate involved in enterobacterial common antigen (ECA) synthesis.


ensembl_gene_id: ETA_02110
symbol: hemD
gene_biotype: protein_coding
description:
  Uroporphyrinogen III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.


ensembl_gene_id: ETA_02120
symbol: hemC
gene_biotype: protein_coding
description:
  Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.


ensembl_gene_id: ETA_02150
symbol: dapF
gene_biotype: protein_coding
description:
  Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.


ensembl_gene_id: ETA_02170
symbol: xerC
gene_biotype: protein_coding
description:
  Tyrosine recombinase XerC; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerD binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerC specifically exchanges t [...]


ensembl_gene_id: ETA_02200
symbol: corA
gene_biotype: protein_coding
description:
  Magnesium transport protein corA; Mediates influx of magnesium ions. Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.


ensembl_gene_id: ETA_02220
symbol: pldA
gene_biotype: protein_coding
description:
  Outer membrane phospholipase A; Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities. Belongs to the phospholipase A1 family.


ensembl_gene_id: ETA_02300
symbol: metR
gene_biotype: protein_coding
description:
  LysR-family transcriptional regulatory protein; silverDB:etchr00229; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: ETA_02310
symbol: metE
gene_biotype: protein_coding
description:
  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.


ensembl_gene_id: ETA_02330
symbol: udp
gene_biotype: protein_coding
description:
  Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family.


ensembl_gene_id: ETA_02350
symbol: ubiE
gene_biotype: protein_coding
description:
  Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2).


ensembl_gene_id: ETA_02370
symbol: ubiB
gene_biotype: protein_coding
description:
  Probable ubiquinone biosynthesis protein UbiB; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.


ensembl_gene_id: ETA_02380
symbol: tatA
gene_biotype: protein_coding
description:
  Probable sec-independent twin-arginine translocase subunit TatA; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.


ensembl_gene_id: ETA_02390
symbol: tatB
gene_biotype: protein_coding
description:
  Probable sec-independent protein translocase protein TatB; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.


ensembl_gene_id: ETA_02400
symbol: tatC
gene_biotype: protein_coding
description:
  Sec-independent protein translocase protein TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.


ensembl_gene_id: ETA_02410
symbol: tatD
gene_biotype: protein_coding
description:
  Deoxyribonuclease; 3'-5' exonuclease that prefers single-stranded DNA and RNA. May play a role in the H(2)O(2)-induced DNA damage repair. Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family. TatD subfamily.


ensembl_gene_id: ETA_02420
symbol: rfaH
gene_biotype: protein_coding
description:
  Transcriptional activator; Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components. RfaH is recruited into a multi-component RNA polymerase complex by the ops element, which is a short conserved DNA sequence located downstream of the main promoter of these operons. Once bound, RfaH suppresses pausing and inhibits Rho-dependent and intrinsic termination at a subset of sites. Termination signals are bypassed, which allows complete synthesis of long RNA chains.


ensembl_gene_id: ETA_02430
symbol: ubiD
gene_biotype: protein_coding
description:
  3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.


ensembl_gene_id: ETA_02450
symbol: fadA
gene_biotype: protein_coding
description:
  3-ketoacyl-CoA thiolase; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.


ensembl_gene_id: ETA_02460
symbol: fadB
gene_biotype: protein_coding
description:
  Fatty oxidation complex alpha subunit; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.


ensembl_gene_id: ETA_02490
symbol: trkH
gene_biotype: protein_coding
description:
  Trk system potassium uptake protein TrkH; Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA; Belongs to the TrkH potassium transport family.


ensembl_gene_id: ETA_02540
symbol: aapJ
gene_biotype: protein_coding
description:
  General L-amino ABC transporter binding protein; silverDB:etchr00253; Belongs to the bacterial solute-binding protein 3 family.


ensembl_gene_id: ETA_02550
symbol: ddg
gene_biotype: protein_coding
description:
  Putative heat shock protein; Catalyzes the transfer of palmitoleate from palmitoleoyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)- (palmitoleoyl)-lipid IV(A); Belongs to the LpxL/LpxM/LpxP family. LpxP subfamily.


ensembl_gene_id: ETA_02720
symbol: fis
gene_biotype: protein_coding
description:
  DNA-binding protein Fis; Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters; Belongs to the transcriptional regulatory Fis family.


ensembl_gene_id: ETA_02730
symbol: dusB
gene_biotype: protein_coding
description:
  tRNA-dihydrouridine synthase B; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily.


ensembl_gene_id: ETA_02740
symbol: prmA
gene_biotype: protein_coding
description:
  Ribosomal protein L11 methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family.


ensembl_gene_id: ETA_02750
symbol: ETA_02750
gene_biotype: protein_coding
description:
  Sodium/pantothenate symporter; silverDB:etchr00274; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: ETA_02770
symbol: accC
gene_biotype: protein_coding
description:
  Acetyl CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.


ensembl_gene_id: ETA_02780
symbol: accB
gene_biotype: protein_coding
description:
  Biotin carboxyl carrier protein of acetyl-CoA carboxylase (BCCP); This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.


ensembl_gene_id: ETA_02790
symbol: aroQ
gene_biotype: protein_coding
description:
  3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.


ensembl_gene_id: ETA_02800
symbol: yedZ
gene_biotype: protein_coding
description:
  Putative membrane protein YedZ; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, [...]


ensembl_gene_id: ETA_02810
symbol: yedY
gene_biotype: protein_coding
description:
  Conserved hypothetical protein YedY; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce bo [...]


ensembl_gene_id: ETA_02860
symbol: mreD
gene_biotype: protein_coding
description:
  Rod shape-determining protein MreD; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins. Belongs to the MreD family.


ensembl_gene_id: ETA_02870
symbol: yhdE
gene_biotype: protein_coding
description:
  Maf-like protein YhdE; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.


ensembl_gene_id: ETA_02910
symbol: tdrA
gene_biotype: protein_coding
description:
  Putative temperature-dependent LysR-family regulator A; silverDB:etchr00290; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: ETA_02930
symbol: aaeA
gene_biotype: protein_coding
description:
  P-hydroxybenzoic acid efflux pump subunit AaeA (pHBA efflux pump protein A); Forms an efflux pump with AaeB; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: ETA_02940
symbol: aaeB
gene_biotype: protein_coding
description:
  P-hydroxybenzoic acid efflux pump subunit AaeB (pHBA efflux pump protein B); Forms an efflux pump with AaeA. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell; Belongs to the aromatic acid exporter ArAE (TC 2.A.85) family.


ensembl_gene_id: ETA_03030
symbol: rplM
gene_biotype: protein_coding
description:
  50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.


ensembl_gene_id: ETA_03040
symbol: rpsI
gene_biotype: protein_coding
description:
  30S ribosomal protein S9; silverDB:etchr00303; Belongs to the universal ribosomal protein uS9 family.


ensembl_gene_id: ETA_03070
symbol: ETA_03070
gene_biotype: protein_coding
description:
  Sulfite reductase; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.


ensembl_gene_id: ETA_03100
symbol: mtgA
gene_biotype: protein_coding
description:
  Monofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family.


ensembl_gene_id: ETA_03120
symbol: yhbJ
gene_biotype: protein_coding
description:
  Conserved hypothetical protein YhbJ; Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ. When glucosamine-6- phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E. Consequently, GlmZ is inactivated and unable to activate GlmS synthesis. Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS; Belongs to the RapZ-like family. RapZ subfamily.


ensembl_gene_id: ETA_03150
symbol: rpoN
gene_biotype: protein_coding
description:
  RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.


ensembl_gene_id: ETA_03170
symbol: yhbN
gene_biotype: protein_coding
description:
  Putative ABC superfamily (Bind_prot) transport protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.


ensembl_gene_id: ETA_03180
symbol: yrbK
gene_biotype: protein_coding
description:
  Possible exported protein YrbK; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family.


ensembl_gene_id: ETA_03190
symbol: kdsC
gene_biotype: protein_coding
description:
  3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family.


ensembl_gene_id: ETA_03270
symbol: yrbA
gene_biotype: protein_coding
description:
  Putative transcriptional regulator (BolA family); silverDB:etchr00326; Belongs to the BolA/IbaG family.


ensembl_gene_id: ETA_03280
symbol: murA
gene_biotype: protein_coding
description:
  UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.


ensembl_gene_id: ETA_03310
symbol: rplU
gene_biotype: protein_coding
description:
  50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.


ensembl_gene_id: ETA_03320
symbol: rpmA
gene_biotype: protein_coding
description:
  50S ribosomal protein L27; silverDB:etchr00331; Belongs to the bacterial ribosomal protein bL27 family.


ensembl_gene_id: ETA_03340
symbol: obg
gene_biotype: protein_coding
description:
  Putative GTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.


ensembl_gene_id: ETA_03380
symbol: greA
gene_biotype: protein_coding
description:
  Transcription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.


ensembl_gene_id: ETA_03390
symbol: yhbY
gene_biotype: protein_coding
description:
  Predicted RNA-binding protein containing KH domain, possibly ribosomal protein; silverDB:etchr00338.


ensembl_gene_id: ETA_03400
symbol: rrmJ
gene_biotype: protein_coding
description:
  Ribosomal RNA large subunit methyltransferase; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.


ensembl_gene_id: ETA_03410
symbol: hflB
gene_biotype: protein_coding
description:
  Cell division protease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family.  In the central section; belongs to the AAA ATPase family.


ensembl_gene_id: ETA_03420
symbol: folP
gene_biotype: protein_coding
description:
  7,8-dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.


ensembl_gene_id: ETA_03430
symbol: glmM
gene_biotype: protein_coding
description:
  Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.


ensembl_gene_id: ETA_03440
symbol: secG
gene_biotype: protein_coding
description:
  Protein-export membrane protein SecG (Preprotein translocase band 1 subunit); Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.


ensembl_gene_id: ETA_03460
symbol: nusA
gene_biotype: protein_coding
description:
  Transcription elongation protein NusA (N utilization substance protein A); Participates in both transcription termination and antitermination.


ensembl_gene_id: ETA_03470
symbol: infB
gene_biotype: protein_coding
description:
  Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.


ensembl_gene_id: ETA_03480
symbol: rbfA
gene_biotype: protein_coding
description:
  Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.


ensembl_gene_id: ETA_03490
symbol: truB
gene_biotype: protein_coding
description:
  tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.


ensembl_gene_id: ETA_03500
symbol: rpsO
gene_biotype: protein_coding
description:
  30S ribosomal protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.


ensembl_gene_id: ETA_03510
symbol: pnp
gene_biotype: protein_coding
description:
  Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.


ensembl_gene_id: ETA_03530
symbol: deaD
gene_biotype: protein_coding
description:
  Cold-shock DEAD-box protein A; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.


ensembl_gene_id: ETA_03580
symbol: nrdG
gene_biotype: protein_coding
description:
  Anaerobic ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.


ensembl_gene_id: ETA_03620
symbol: pyrI
gene_biotype: protein_coding
description:
  Aspartate transcarbamylase regulatory subunit PyrI; Involved in allosteric regulation of aspartate carbamoyltransferase.


ensembl_gene_id: ETA_03630
symbol: pyrB
gene_biotype: protein_coding
description:
  Aspartate transcarbamylase catalytic subunit PyrB; silverDB:etchr00363; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.


ensembl_gene_id: ETA_03640
symbol: argI
gene_biotype: protein_coding
description:
  Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.


ensembl_gene_id: ETA_03650
symbol: yjgD
gene_biotype: protein_coding
description:
  Conserved hypothetical protein YjgD; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.


ensembl_gene_id: ETA_03680
symbol: valS
gene_biotype: protein_coding
description:
  Valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.


ensembl_gene_id: ETA_03700
symbol: pepA
gene_biotype: protein_coding
description:
  Probable cytosol aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.


ensembl_gene_id: ETA_04140
symbol: mug
gene_biotype: protein_coding
description:
  G/U mismatch-specific DNA glycosylase; silverDB:etchr00414; Belongs to the uracil-DNA glycosylase (UDG) superfamily. TDG/mug family.


ensembl_gene_id: ETA_04150
symbol: rpoD
gene_biotype: protein_coding
description:
  Sigma D (Sigma 70) factor of RNA polymerase; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.


ensembl_gene_id: ETA_04160
symbol: dnaG
gene_biotype: protein_coding
description:
  DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.


ensembl_gene_id: ETA_04170
symbol: rpsU
gene_biotype: protein_coding
description:
  30S ribosomal protein S21; silverDB:etchr00417; Belongs to the bacterial ribosomal protein bS21 family.


ensembl_gene_id: ETA_04180
symbol: gcp
gene_biotype: protein_coding
description:
  Probable O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.


ensembl_gene_id: ETA_04190
symbol: plsY
gene_biotype: protein_coding
description:
  Putative membrane protein; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.


ensembl_gene_id: ETA_04200
symbol: ETA_04200
gene_biotype: protein_coding
description:
  Putative dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.


ensembl_gene_id: ETA_04210
symbol: uppP
gene_biotype: protein_coding
description:
  Undecaprenyl-diphosphatase (Bacitracin resistance protein); Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.


ensembl_gene_id: ETA_04220
symbol: cca
gene_biotype: protein_coding
description:
  tRNA nucleotidyl transferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.


ensembl_gene_id: ETA_04250
symbol: glnE
gene_biotype: protein_coding
description:
  Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...]


ensembl_gene_id: ETA_04260
symbol: hldE
gene_biotype: protein_coding
description:
  D-beta-D-heptose 1-phosphate adenylyltransferase; Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7- phosphate at the C-1 position to selectively form D-glycero-beta-D- manno-heptose-1,7-bisphosphate; In the C-terminal section; belongs to the cytidylyltransferase family.


ensembl_gene_id: ETA_04280
symbol: ribB
gene_biotype: protein_coding
description:
  3,4-dihydroxy-2-butanone 4-phosphate synthase (DHBP synthase); Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.


ensembl_gene_id: ETA_04350
symbol: icc
gene_biotype: protein_coding
description:
  Putative Icc protein; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.


ensembl_gene_id: ETA_04370
symbol: parE
gene_biotype: protein_coding
description:
  DNA topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily.


ensembl_gene_id: ETA_04380
symbol: ETA_04380
gene_biotype: protein_coding
description:
  LysR-family transcriptional regulator; silverDB:etchr00438; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: ETA_04410
symbol: parC
gene_biotype: protein_coding
description:
  DNA topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.


ensembl_gene_id: ETA_04420
symbol: plsC
gene_biotype: protein_coding
description:
  1-acyl-sn-glycerol-3-phosphate acyltransferase; silverDB:etchr00442; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.


ensembl_gene_id: ETA_04430
symbol: sufI
gene_biotype: protein_coding
description:
  Putative cell division protein; Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress; Belongs to the FtsP family.


ensembl_gene_id: ETA_04460
symbol: dat
gene_biotype: protein_coding
description:
  Diaminobutyrate-2-oxoglutarate aminotransferase; silverDB:etchr00446; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: ETA_04540
symbol: csuE
gene_biotype: protein_coding
description:
  CsuE protein (chaperone-usher pili assembly system), hypothetical secreted protein; silverDB:etchr00454.


ensembl_gene_id: ETA_04550
symbol: csuD
gene_biotype: protein_coding
description:
  CsuD protein (chaperone-usher pili assembly system), similar to fimbrial usher proteins; silverDB:etchr00455.


ensembl_gene_id: ETA_04560
symbol: csuC
gene_biotype: protein_coding
description:
  CsuC protein, similar to fimbrial chaperone proteins (chaperone-usher pili assembly system); silverDB:etchr00456.


ensembl_gene_id: ETA_04590
symbol: ETA_04590
gene_biotype: protein_coding
description:
  Putative bifunctional protein [GntR-family transcriptional regulator and aminotransferase]; silverDB:etchr00459.


ensembl_gene_id: ETA_04700
symbol: cbrB
gene_biotype: protein_coding
description:
  Achromobactin transport system permease protein; silverDB:etchr00470; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: ETA_04710
symbol: cbrC
gene_biotype: protein_coding
description:
  Achromobactin transport system permease protein; silverDB:etchr00471; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: ETA_04750
symbol: ETA_04750
gene_biotype: protein_coding
description:
  Putative transposase, fragment; silverDB:etchr00474; Belongs to the bacterial solute-binding protein 3 family.


ensembl_gene_id: ETA_04790
symbol: bglA
gene_biotype: protein_coding
description:
  BglA protein, 6-phospho-beta-glucosidase (involved in beta-glucoside utilization); silverDB:etchr00479; Belongs to the glycosyl hydrolase 1 family.


ensembl_gene_id: ETA_04820
symbol: bglF
gene_biotype: protein_coding
description:
  BglF protein (involved in beta-glucoside utilization); The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.


ensembl_gene_id: ETA_05070
symbol: ampR
gene_biotype: protein_coding
description:
  AmpR transcriptional regulator; silverDB:etchr00507; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: ETA_05230
symbol: hrpL
gene_biotype: protein_coding
description:
  Sigma factor HrpL (hrp cluster); silverDB:etchr00523; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: ETA_05440
symbol: rlsA
gene_biotype: protein_coding
description:
  RlsA protein (transcriptional regulator of levansucrase); silverDB:etchr00544; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: ETA_06060
symbol: yjjT
gene_biotype: protein_coding
description:
  Ribosomal RNA small subunit methyltransferase C; Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle; Belongs to the methyltransferase superfamily. RsmC family.


ensembl_gene_id: ETA_06070
symbol: holD
gene_biotype: protein_coding
description:
  DNA polymerase III, psi subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown.


ensembl_gene_id: ETA_06080
symbol: rimI
gene_biotype: protein_coding
description:
  Ribosomal-protein-alanine acetyltransferase; Acetylates the N-terminal alanine of ribosomal protein S18.


ensembl_gene_id: ETA_06610
symbol: prfC
gene_biotype: protein_coding
description:
  Peptide chain release factor 3 (RF-3); Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.


ensembl_gene_id: ETA_06660
symbol: deoC2
gene_biotype: protein_coding
description:
  Deoxyribose-phosphate aldolase 2; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily.


ensembl_gene_id: ETA_06670
symbol: deoA
gene_biotype: protein_coding
description:
  Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.


ensembl_gene_id: ETA_06680
symbol: deoB
gene_biotype: protein_coding
description:
  Phosphopentomutase precursor; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family.


ensembl_gene_id: ETA_06730
symbol: radA
gene_biotype: protein_coding
description:
  DNA repair protein radA (DNA repair protein sms); DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.


ensembl_gene_id: ETA_06770
symbol: ETA_06770
gene_biotype: protein_coding
description:
  Zinc-containing alcohol dehydrogenase superfamily; silverDB:etchr00669; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.


ensembl_gene_id: ETA_06780
symbol: ETA_06780
gene_biotype: protein_coding
description:
  LysR-family transcriptional activator; silverDB:etchr00670; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: ETA_06840
symbol: ETA_06840
gene_biotype: protein_coding
description:
  Putative branched-chain amino acid transport system, permease component; silverDB:etchr00676; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: ETA_06850
symbol: ETA_06850
gene_biotype: protein_coding
description:
  Putative branched-chain amino acid transport system, permease component; silverDB:etchr00677; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: ETA_06910
symbol: trpR
gene_biotype: protein_coding
description:
  Trp operon repressor; This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region.


ensembl_gene_id: ETA_06920
symbol: ETA_06920
gene_biotype: protein_coding
description:
  Conserved hypothetical protein (DUF84); Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.


ensembl_gene_id: ETA_06930
symbol: gpmB
gene_biotype: protein_coding
description:
  Probable phosphoglycerate mutase; silverDB:etchr00685; Belongs to the phosphoglycerate mutase family. GpmB subfamily.


ensembl_gene_id: ETA_06980
symbol: thrA
gene_biotype: protein_coding
description:
  Bifunctional aspartokinase/homoserine dehydrogenase I (AKI-HDI); silverDB:etchr00690; In the C-terminal section; belongs to the homoserine dehydrogenase family.


ensembl_gene_id: ETA_06990
symbol: thrB
gene_biotype: protein_coding
description:
  Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.


ensembl_gene_id: ETA_07020
symbol: talB
gene_biotype: protein_coding
description:
  Transaldolase B; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.


ensembl_gene_id: ETA_07050
symbol: dnaK
gene_biotype: protein_coding
description:
  Chaperone protein dnaK (Heat shock 70 kDa protein); Acts as a chaperone; Belongs to the heat shock protein 70 family.


ensembl_gene_id: ETA_07060
symbol: dnaJ
gene_biotype: protein_coding
description:
  Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]


ensembl_gene_id: ETA_07080
symbol: nhaA
gene_biotype: protein_coding
description:
  Na(+)/H(+) antiporter 1; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.


ensembl_gene_id: ETA_07120
symbol: ileS
gene_biotype: protein_coding
description:
  Isoleucyl-tRNA synthetase 1; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.


ensembl_gene_id: ETA_07130
symbol: lspA
gene_biotype: protein_coding
description:
  Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.


ensembl_gene_id: ETA_07150
symbol: ispH
gene_biotype: protein_coding
description:
  4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.


ensembl_gene_id: ETA_07160
symbol: dapB
gene_biotype: protein_coding
description:
  Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.


ensembl_gene_id: ETA_07210
symbol: folA
gene_biotype: protein_coding
description:
  Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.


ensembl_gene_id: ETA_07220
symbol: apaH
gene_biotype: protein_coding
description:
  Bis(5'-nucleosyl)-tetraphosphatase, symmetrical; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family.


ensembl_gene_id: ETA_07240
symbol: ksgA
gene_biotype: protein_coding
description:
  Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.


ensembl_gene_id: ETA_07250
symbol: pdxA
gene_biotype: protein_coding
description:
  4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).


ensembl_gene_id: ETA_07260
symbol: surA
gene_biotype: protein_coding
description:
  Peptidyl-prolyl cis-trans isomerase, survival protein; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.


ensembl_gene_id: ETA_07270
symbol: imp
gene_biotype: protein_coding
description:
  Organic solvent tolerance protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.


ensembl_gene_id: ETA_07280
symbol: djlA
gene_biotype: protein_coding
description:
  DnaJ like chaperone protein; Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.


ensembl_gene_id: ETA_07290
symbol: rluA
gene_biotype: protein_coding
description:
  Ribosomal large subunit pseudouridine synthase A; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.


ensembl_gene_id: ETA_07300
symbol: rapA
gene_biotype: protein_coding
description:
  RNA polymerase-associated protein; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily.


ensembl_gene_id: ETA_07330
symbol: thiQ
gene_biotype: protein_coding
description:
  Thiamine transport ATP-binding protein; Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Thiamine importer (TC 3.A.1.19.1) family.


ensembl_gene_id: ETA_07390
symbol: leuD
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.


ensembl_gene_id: ETA_07400
symbol: leuC
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.


ensembl_gene_id: ETA_07410
symbol: leuB
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.


ensembl_gene_id: ETA_07420
symbol: leuA
gene_biotype: protein_coding
description:
  2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.


ensembl_gene_id: ETA_07460
symbol: mraZ
gene_biotype: protein_coding
description:
  Protein MraZ; Negatively regulates its own expression and that of the subsequent genes in the proximal part of the division and cell wall (dcw) gene cluster. Acts by binding directly to DNA. May also regulate the expression of genes outside the dcw cluster.


ensembl_gene_id: ETA_07470
symbol: mraW
gene_biotype: protein_coding
description:
  S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.


ensembl_gene_id: ETA_07480
symbol: ftsL
gene_biotype: protein_coding
description:
  Cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.


ensembl_gene_id: ETA_07490
symbol: ftsI
gene_biotype: protein_coding
description:
  Peptidoglycan synthetase; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily.


ensembl_gene_id: ETA_07500
symbol: murE
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.


ensembl_gene_id: ETA_07510
symbol: murF
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.


ensembl_gene_id: ETA_07520
symbol: mraY
gene_biotype: protein_coding
description:
  Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.


ensembl_gene_id: ETA_07530
symbol: murD
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.


ensembl_gene_id: ETA_07540
symbol: ftsW
gene_biotype: protein_coding
description:
  Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily.


ensembl_gene_id: ETA_07550
symbol: murG
gene_biotype: protein_coding
description:
  Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.


ensembl_gene_id: ETA_07580
symbol: ftsQ
gene_biotype: protein_coding
description:
  Cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.


ensembl_gene_id: ETA_07590
symbol: ftsA
gene_biotype: protein_coding
description:
  Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.


ensembl_gene_id: ETA_07600
symbol: ftsZ
gene_biotype: protein_coding
description:
  Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.


ensembl_gene_id: ETA_07610
symbol: lpxC
gene_biotype: protein_coding
description:
  UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family.


ensembl_gene_id: ETA_07630
symbol: secM
gene_biotype: protein_coding
description:
  Secretion monitor precursor; Regulates secA expression by translational coupling of the secM secA operon. Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation initiation. Belongs to the SecM family.


ensembl_gene_id: ETA_07640
symbol: secA
gene_biotype: protein_coding
description:
  Preprotein translocase secA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.


ensembl_gene_id: ETA_07690
symbol: betT
gene_biotype: protein_coding
description:
  High-affinity choline transport protein; silverDB:etchr00760; Belongs to the BCCT transporter (TC 2.A.15) family.


ensembl_gene_id: ETA_07730
symbol: thiG
gene_biotype: protein_coding
description:
  Thiazole biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.


ensembl_gene_id: ETA_07780
symbol: ETA_07780
gene_biotype: protein_coding
description:
  LysR-like transcriptional regulator; silverDB:etchr00769; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: ETA_07790
symbol: msrA
gene_biotype: protein_coding
description:
  Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.


ensembl_gene_id: ETA_07820
symbol: outO
gene_biotype: protein_coding
description:
  Type IV-A prepilin peptidase PilD; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.


ensembl_gene_id: ETA_07910
symbol: outE
gene_biotype: protein_coding
description:
  Type II secretion system protein E; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.


ensembl_gene_id: ETA_07950
symbol: mutT
gene_biotype: protein_coding
description:
  Mutator protein MutT (7,8-dihydro-8-oxoguanine-triphosphatase); silverDB:etchr00786; Belongs to the Nudix hydrolase family.


ensembl_gene_id: ETA_07960
symbol: yacG
gene_biotype: protein_coding
description:
  Zinc-binding protein YacG; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C- terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.


ensembl_gene_id: ETA_07970
symbol: yacF
gene_biotype: protein_coding
description:
  Conserved hypothetical protein YacF; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.


ensembl_gene_id: ETA_07980
symbol: coaE
gene_biotype: protein_coding
description:
  Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.


ensembl_gene_id: ETA_07990
symbol: guaC
gene_biotype: protein_coding
description:
  Guanosine 5'-monophosphate oxidoreductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.


ensembl_gene_id: ETA_08050
symbol: ETA_08050
gene_biotype: protein_coding
description:
  Putative transcriptional regulator protein, LysR family; silverDB:etchr00796; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: ETA_08140
symbol: aceE
gene_biotype: protein_coding
description:
  Pyruvate dehydrogenase, E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


ensembl_gene_id: ETA_08150
symbol: aceF
gene_biotype: protein_coding
description:
  Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


ensembl_gene_id: ETA_08160
symbol: lpdA
gene_biotype: protein_coding
description:
  Pyruvate dehydrogenase multienzyme complex, Dihydrolipoamide dehydrogenase component; silverDB:etchr00807.


ensembl_gene_id: ETA_08170
symbol: cylG
gene_biotype: protein_coding
description:
  3-oxoacyl-[acyl-carrier protein] reductase; silverDB:etchr00808; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: ETA_08250
symbol: ETA_08250
gene_biotype: protein_coding
description:
  Carnitinyl-CoA dehydratase; silverDB:etchr00816; Belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: ETA_08280
symbol: acnB
gene_biotype: protein_coding
description:
  Aconitate hydratase 2 (Citrate hydro-lyase 2); silverDB:etchr00819; Belongs to the aconitase/IPM isomerase family.


ensembl_gene_id: ETA_08300
symbol: speD
gene_biotype: protein_coding
description:
  S-adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.


ensembl_gene_id: ETA_08310
symbol: speE
gene_biotype: protein_coding
description:
  Spermidine synthase (Putrescine aminopropyltransferase); Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.


ensembl_gene_id: ETA_08380
symbol: cas1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.


ensembl_gene_id: ETA_08510
symbol: hpt
gene_biotype: protein_coding
description:
  Hypoxanthine phosphoribosyltransferase; silverDB:etchr00842; Belongs to the purine/pyrimidine phosphoribosyltransferase family.


ensembl_gene_id: ETA_08520
symbol: yadF
gene_biotype: protein_coding
description:
  Putative carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family.


ensembl_gene_id: ETA_08550
symbol: panD
gene_biotype: protein_coding
description:
  Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.


ensembl_gene_id: ETA_08560
symbol: panC
gene_biotype: protein_coding
description:
  Pantoate-beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.


ensembl_gene_id: ETA_08570
symbol: panB
gene_biotype: protein_coding
description:
  3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.


ensembl_gene_id: ETA_08590
symbol: pcnB
gene_biotype: protein_coding
description:
  Poly(A) polymerase; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control. Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.


ensembl_gene_id: ETA_08600
symbol: gluQ
gene_biotype: protein_coding
description:
  Glutamyl-Q tRNA(Asp) synthetase; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.


ensembl_gene_id: ETA_08610
symbol: dksA
gene_biotype: protein_coding
description:
  DnaK suppressor protein (DnaK suppressor protein homologue); Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.


ensembl_gene_id: ETA_08640
symbol: mrcB
gene_biotype: protein_coding
description:
  Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).


ensembl_gene_id: ETA_08780
symbol: fhuB
gene_biotype: protein_coding
description:
  Ferrichrome transport protein FhuB; silverDB:etchr00869; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: ETA_08820
symbol: mtn
gene_biotype: protein_coding
description:
  Mta/Sah nucleosidase (P46); Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulation. Belongs to the PNP/UDP phosph [...]


ensembl_gene_id: ETA_08830
symbol: dgt
gene_biotype: protein_coding
description:
  Deoxyguanosinetriphosphate triphosphohydrolase; dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs; Belongs to the dGTPase family. Type 1 subfamily.


ensembl_gene_id: ETA_08870
symbol: glnD
gene_biotype: protein_coding
description:
  [Protein-PII] uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.


ensembl_gene_id: ETA_08880
symbol: map
gene_biotype: protein_coding
description:
  Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.


ensembl_gene_id: ETA_08890
symbol: rpsB
gene_biotype: protein_coding
description:
  30S ribosomal protein S2; silverDB:etchr00880; Belongs to the universal ribosomal protein uS2 family.


ensembl_gene_id: ETA_08910
symbol: tsf
gene_biotype: protein_coding
description:
  Elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.


ensembl_gene_id: ETA_08930
symbol: frr
gene_biotype: protein_coding
description:
  Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.


ensembl_gene_id: ETA_08940
symbol: dxr
gene_biotype: protein_coding
description:
  1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP).


ensembl_gene_id: ETA_08950
symbol: uppS
gene_biotype: protein_coding
description:
  Undecaprenyl pyrophosphate synthetase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.


ensembl_gene_id: ETA_08980
symbol: yaeT
gene_biotype: protein_coding
description:
  Outer membrane protein assembly factor YaeT; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamD, the core component of the assembly machinery.


ensembl_gene_id: ETA_09000
symbol: lpxD
gene_biotype: protein_coding
description:
  UDP-3-O-(3-hydroxymyristoyl)-glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O- (hydroxytetradecanoyl)glucosamine using 3-hydroxytetradecanoyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell; Belongs to the transferase hexapeptide repeat family. LpxD subfamily.


ensembl_gene_id: ETA_09010
symbol: fabZ
gene_biotype: protein_coding
description:
  (3R)-hydroxymyristol acyl carrier protein dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.


ensembl_gene_id: ETA_09020
symbol: lpxA
gene_biotype: protein_coding
description:
  Acyl-[acyl-carrier-protein]-UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: ETA_09030
symbol: lpxB
gene_biotype: protein_coding
description:
  Lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: ETA_09040
symbol: rnhB
gene_biotype: protein_coding
description:
  Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.


ensembl_gene_id: ETA_09060
symbol: accA
gene_biotype: protein_coding
description:
  Acetyl-coenzyme A carboxylase carboxyl transferase alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.


ensembl_gene_id: ETA_09090
symbol: tilS
gene_biotype: protein_coding
description:
  tRNA(Ile)-lysidine synthase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.


ensembl_gene_id: ETA_09150
symbol: proS
gene_biotype: protein_coding
description:
  Prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...]


ensembl_gene_id: ETA_09170
symbol: rcsF
gene_biotype: protein_coding
description:
  Regulator in colanic acid synthesis; Essential component of the Rcs signaling system, which controls transcription of numerous genes. Plays a role in signal transduction from the cell surface to the histidine kinase RcsC. May detect outer membrane defects; Belongs to the RcsF family.


ensembl_gene_id: ETA_09200
symbol: metN
gene_biotype: protein_coding
description:
  D-methionine transport ATP-binding protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.


ensembl_gene_id: ETA_09240
symbol: pssA
gene_biotype: protein_coding
description:
  Phosphatidylserine synthase (CDP-diacylglycerol-serine O-phosphatidyltransferase); silverDB:etchr00915.


ensembl_gene_id: ETA_09280
symbol: spoU-2
gene_biotype: protein_coding
description:
  Predicted tRNA/rRNA methyltransferase; silverDB:etchr00919; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.


ensembl_gene_id: ETA_09370
symbol: nrdF
gene_biotype: protein_coding
description:
  Ribonucleoside-diphosphate reductase 2, beta subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.


ensembl_gene_id: ETA_09380
symbol: nrdE
gene_biotype: protein_coding
description:
  Ribonucleoside-diphosphate reductase 2, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.


ensembl_gene_id: ETA_09500
symbol: flhD-2
gene_biotype: protein_coding
description:
  Flagellar transcriptional activator; Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhD family.


ensembl_gene_id: ETA_09510
symbol: flhC-2
gene_biotype: protein_coding
description:
  Flagellum biosynthesis transcription activator; Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhC family.


ensembl_gene_id: ETA_09550
symbol: scrB
gene_biotype: protein_coding
description:
  Sucrose-6-phosphate hydrolase; Enables the bacterium to metabolize sucrose as a sole carbon source; Belongs to the glycosyl hydrolase 32 family.


ensembl_gene_id: ETA_09720
symbol: smpB
gene_biotype: protein_coding
description:
  Small protein B, tmRNA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosom [...]


ensembl_gene_id: ETA_09750
symbol: smpA
gene_biotype: protein_coding
description:
  Small protein A; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: ETA_09760
symbol: recN
gene_biotype: protein_coding
description:
  Protein used in recombination and DNA repair (DNA repair protein RecN); May be involved in recombinational repair of damaged DNA.


ensembl_gene_id: ETA_09770
symbol: ppnK
gene_biotype: protein_coding
description:
  Probable inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.


ensembl_gene_id: ETA_09780
symbol: grpE
gene_biotype: protein_coding
description:
  Heat shock protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depen [...]


ensembl_gene_id: ETA_09790
symbol: ung
gene_biotype: protein_coding
description:
  Uracil-DNA-glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.


ensembl_gene_id: ETA_09800
symbol: grcA
gene_biotype: protein_coding
description:
  Autonomous glycyl radical cofactor; Acts as a radical domain for damaged PFL and possibly other radical proteins.


ensembl_gene_id: ETA_09810
symbol: srmB
gene_biotype: protein_coding
description:
  ATP-dependent RNA helicase; DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity; Belongs to the DEAD box helicase family. SrmB subfamily.


ensembl_gene_id: ETA_09820
symbol: yfiC
gene_biotype: protein_coding
description:
  Putative enzyme; Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).


ensembl_gene_id: ETA_09850
symbol: rseA
gene_biotype: protein_coding
description:
  Anti sigma E (Sigma 24) factor, negative regulator; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytop [...]


ensembl_gene_id: ETA_09900
symbol: lepA
gene_biotype: protein_coding
description:
  GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.


ensembl_gene_id: ETA_09920
symbol: rnc
gene_biotype: protein_coding
description:
  Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.


ensembl_gene_id: ETA_09930
symbol: era
gene_biotype: protein_coding
description:
  GTP-binding protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.


ensembl_gene_id: ETA_09950
symbol: pdxJ
gene_biotype: protein_coding
description:
  Pyridoxal phosphate biosynthetic protein (PNP synthase); Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.


ensembl_gene_id: ETA_09960
symbol: acpS
gene_biotype: protein_coding
description:
  Holo-[acyl-carrier-protein] synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.


ensembl_gene_id: ETA_10030
symbol: murQ
gene_biotype: protein_coding
description:
  Putative phosphosugar-binding protein; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.


ensembl_gene_id: ETA_10050
symbol: tadA
gene_biotype: protein_coding
description:
  tRNA-specific adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.


ensembl_gene_id: ETA_10060
symbol: mltF
gene_biotype: protein_coding
description:
  Putative transglycosylase; Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella. In the N-terminal section; belongs to the bacterial solute- binding protein 3 family.


ensembl_gene_id: ETA_10070
symbol: purL
gene_biotype: protein_coding
description:
  Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.


ensembl_gene_id: ETA_10130
symbol: glyA
gene_biotype: protein_coding
description:
  Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.


ensembl_gene_id: ETA_10160
symbol: ETA_10160
gene_biotype: protein_coding
description:
  Putative membrane protein; silverDB:etchr01007; Belongs to the NiCoT transporter (TC 2.A.52) family.


ensembl_gene_id: ETA_10170
symbol: suhB
gene_biotype: protein_coding
description:
  Inositol-1-monophosphatase; silverDB:etchr01008; Belongs to the inositol monophosphatase superfamily.


ensembl_gene_id: ETA_10180
symbol: trmJ
gene_biotype: protein_coding
description:
  tRNA/rRNA methyltransferase; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.


ensembl_gene_id: ETA_10190
symbol: iscR
gene_biotype: protein_coding
description:
  Predicted transcriptional regulator; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.


ensembl_gene_id: ETA_10200
symbol: iscS
gene_biotype: protein_coding
description:
  Cysteine desulfurase (NifS protein homolog); Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.


ensembl_gene_id: ETA_10210
symbol: pepB
gene_biotype: protein_coding
description:
  Peptidase B (Aminopeptidase B); Probably plays an important role in intracellular peptide degradation.


ensembl_gene_id: ETA_10240
symbol: ndk
gene_biotype: protein_coding
description:
  Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.


ensembl_gene_id: ETA_10250
symbol: yfgB
gene_biotype: protein_coding
description:
  Conserved hypothetical protein YfgB; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family.


ensembl_gene_id: ETA_10270
symbol: yfgA
gene_biotype: protein_coding
description:
  Conserved hypothetical protein YfgA; Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis.


ensembl_gene_id: ETA_10280
symbol: ispG
gene_biotype: protein_coding
description:
  4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family.


ensembl_gene_id: ETA_10310
symbol: bamB
gene_biotype: protein_coding
description:
  Putative lipoprotein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: ETA_10320
symbol: engA
gene_biotype: protein_coding
description:
  GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.


ensembl_gene_id: ETA_10340
symbol: xseA
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family.


ensembl_gene_id: ETA_10350
symbol: guaB
gene_biotype: protein_coding
description:
  Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.


ensembl_gene_id: ETA_10510
symbol: ppk
gene_biotype: protein_coding
description:
  Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family.


ensembl_gene_id: ETA_10540
symbol: pstB-2
gene_biotype: protein_coding
description:
  Phosphate import ATP-binding protein (ABC phosphate transporter); Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.


ensembl_gene_id: ETA_10550
symbol: purN
gene_biotype: protein_coding
description:
  Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.


ensembl_gene_id: ETA_10600
symbol: hda
gene_biotype: protein_coding
description:
  DnaA-homolog protein hda; Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA; Belongs to the DnaA family. HdA subfamily.


ensembl_gene_id: ETA_10620
symbol: bepA
gene_biotype: protein_coding
description:
  Putative exported protein; Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.


ensembl_gene_id: ETA_10660
symbol: dapA
gene_biotype: protein_coding
description:
  Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).


ensembl_gene_id: ETA_10670
symbol: nlpB
gene_biotype: protein_coding
description:
  Lipoprotein-34; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: ETA_10680
symbol: purC
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazole-succinocarboxamide synthase; silverDB:etchr01059; Belongs to the SAICAR synthetase family.


ensembl_gene_id: ETA_10700
symbol: ypfI
gene_biotype: protein_coding
description:
  Conserved hypothetical protein YpfI; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).


ensembl_gene_id: ETA_10720
symbol: dapE
gene_biotype: protein_coding
description:
  N-succinyl-diaminopimelate deacylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily.


ensembl_gene_id: ETA_10830
symbol: tktB
gene_biotype: protein_coding
description:
  Transketolase 2; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.


ensembl_gene_id: ETA_10840
symbol: talA
gene_biotype: protein_coding
description:
  Transaldolase A; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.


ensembl_gene_id: ETA_10850
symbol: hemF
gene_biotype: protein_coding
description:
  Coproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX.


ensembl_gene_id: ETA_10910
symbol: cysT
gene_biotype: protein_coding
description:
  Sulfate ABC transporter permease; Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: ETA_10930
symbol: cysA
gene_biotype: protein_coding
description:
  Sulfate/thiosulfate import ATP-binding protein; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system.


ensembl_gene_id: ETA_10940
symbol: cysM
gene_biotype: protein_coding
description:
  Cysteine synthase B (O-acetylserine sulfhydrolase B); silverDB:etchr01085; Belongs to the cysteine synthase/cystathionine beta- synthase family.


ensembl_gene_id: ETA_10980
symbol: ptsI
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).


ensembl_gene_id: ETA_11000
symbol: cysK
gene_biotype: protein_coding
description:
  Cysteine synthase A; silverDB:etchr01091; Belongs to the cysteine synthase/cystathionine beta- synthase family.


ensembl_gene_id: ETA_11010
symbol: cysZ
gene_biotype: protein_coding
description:
  Protein cysZ homolog; High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway; Belongs to the CysZ family.


ensembl_gene_id: ETA_11020
symbol: zipA
gene_biotype: protein_coding
description:
  Cell division protein zipA homolog; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.


ensembl_gene_id: ETA_11030
symbol: lig
gene_biotype: protein_coding
description:
  DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.


ensembl_gene_id: ETA_11060
symbol: yfeR
gene_biotype: protein_coding
description:
  LysR family transcriptional regulator; silverDB:etchr01097; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: ETA_11070
symbol: gltX
gene_biotype: protein_coding
description:
  Glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).


ensembl_gene_id: ETA_11100
symbol: nupC
gene_biotype: protein_coding
description:
  Nucleoside permease; silverDB:etchr01101; Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.


ensembl_gene_id: ETA_11110
symbol: mntH
gene_biotype: protein_coding
description:
  Putative transport system permease; H(+)-stimulated, divalent metal cation uptake system. Belongs to the NRAMP family.


ensembl_gene_id: ETA_11370
symbol: ccmA
gene_biotype: protein_coding
description:
  Cytochrome c biogenesis ATP-binding export protein; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.


ensembl_gene_id: ETA_11380
symbol: ccmB
gene_biotype: protein_coding
description:
  Heme exporter protein B; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family.


ensembl_gene_id: ETA_11390
symbol: ccmC
gene_biotype: protein_coding
description:
  Heme exporter protein C; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family.


ensembl_gene_id: ETA_11400
symbol: ccmD
gene_biotype: protein_coding
description:
  Putative heme exporter protein D; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmD/CycX/HelD family.


ensembl_gene_id: ETA_11410
symbol: ccmE
gene_biotype: protein_coding
description:
  Cytochrome c-type biogenesis protein (Heme chaperone CcmE); Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family.


ensembl_gene_id: ETA_11430
symbol: ccmG
gene_biotype: protein_coding
description:
  Cytochrome c biogenesis protein CcmG (Thiol:disulfide interchange protein DsbE); silverDB:etchr01134.


ensembl_gene_id: ETA_11500
symbol: fadJ
gene_biotype: protein_coding
description:
  Fatty acid oxidation complex alpha subunit; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: ETA_11530
symbol: yfcB
gene_biotype: protein_coding
description:
  Probable adenine-specific methylase; Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue; Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.


ensembl_gene_id: ETA_11540
symbol: aroC
gene_biotype: protein_coding
description:
  Chorismate synthase (5-enolpyruvylshikimate-3-phosphate phospholyase); Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.


ensembl_gene_id: ETA_11550
symbol: mepA
gene_biotype: protein_coding
description:
  Penicillin-insensitive murein endopeptidase precursor; Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus.


ensembl_gene_id: ETA_11590
symbol: mnmC
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family.


ensembl_gene_id: ETA_11600
symbol: fabB
gene_biotype: protein_coding
description:
  3-oxoacyl-[acyl-carrier-protein] synthase 1; silverDB:etchr01151; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: ETA_11670
symbol: pdxB
gene_biotype: protein_coding
description:
  Erythronate-4-phosphate dehydrogenase; Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate.


ensembl_gene_id: ETA_11680
symbol: ETA_11680
gene_biotype: protein_coding
description:
  Aspartate-semialdehyde dehydrogenase; silverDB:etchr01159; Belongs to the aspartate-semialdehyde dehydrogenase family.


ensembl_gene_id: ETA_11690
symbol: truA
gene_biotype: protein_coding
description:
  tRNA pseudouridylate synthase I; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.


ensembl_gene_id: ETA_11730
symbol: accD
gene_biotype: protein_coding
description:
  AcetylCoA carboxylase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.


ensembl_gene_id: ETA_11740
symbol: folC
gene_biotype: protein_coding
description:
  FolC bifunctional protein; Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10- formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.


ensembl_gene_id: ETA_11750
symbol: dedD
gene_biotype: protein_coding
description:
  Putative membrane protein; Non-essential cell division protein that could be required for efficient cell constriction.


ensembl_gene_id: ETA_11780
symbol: purF
gene_biotype: protein_coding
description:
  Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.


ensembl_gene_id: ETA_11790
symbol: ubiX
gene_biotype: protein_coding
description:
  3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family.


ensembl_gene_id: ETA_11900
symbol: goaG
gene_biotype: protein_coding
description:
  4-aminobutyrate aminotransferase; silverDB:etchr01181; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: ETA_11920
symbol: potA
gene_biotype: protein_coding
description:
  ATP hydrolase of ABC transporter; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.


ensembl_gene_id: ETA_11930
symbol: pta
gene_biotype: protein_coding
description:
  Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.


ensembl_gene_id: ETA_11940
symbol: ackA
gene_biotype: protein_coding
description:
  Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.


ensembl_gene_id: ETA_12010
symbol: yfbR
gene_biotype: protein_coding
description:
  5'-nucleotidase YfbR (Nucleoside 5'-monophosphate phosphohydrolase); Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates.


ensembl_gene_id: ETA_12030
symbol: hexS
gene_biotype: protein_coding
description:
  LysR-family transcriptional regulator; silverDB:etchr01194; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: ETA_12040
symbol: nuoA
gene_biotype: protein_coding
description:
  NADH dehydrogenase I chain A; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family.


ensembl_gene_id: ETA_12050
symbol: nuoB
gene_biotype: protein_coding
description:
  NADH dehydrogenase I chain B; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: ETA_12060
symbol: nuoC
gene_biotype: protein_coding
description:
  NADH dehydrogenase I C/D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family.


ensembl_gene_id: ETA_12080
symbol: nuoF
gene_biotype: protein_coding
description:
  NADH dehydrogenase I chain F; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family.


ensembl_gene_id: ETA_12090
symbol: nuoG
gene_biotype: protein_coding
description:
  NADH dehydrogenase I chain G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family.


ensembl_gene_id: ETA_12100
symbol: nuoH
gene_biotype: protein_coding
description:
  NADH dehydrogenase I subunit H; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.


ensembl_gene_id: ETA_12110
symbol: nuoI
gene_biotype: protein_coding
description:
  NADH dehydrogenase I subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: ETA_12120
symbol: nuoJ
gene_biotype: protein_coding
description:
  NADH dehydrogenase I chain J; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: ETA_12130
symbol: nuoK
gene_biotype: protein_coding
description:
  NADH dehydrogenase I chain K; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family.


ensembl_gene_id: ETA_12160
symbol: nuoN
gene_biotype: protein_coding
description:
  NADH dehydrogenase I chain N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family.


ensembl_gene_id: ETA_12180
symbol: mdoD
gene_biotype: protein_coding
description:
  Glucans biosynthesis protein D; Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).


ensembl_gene_id: ETA_12200
symbol: kup-2
gene_biotype: protein_coding
description:
  Low-affinity potassium transport protein; Responsible for the low-affinity transport of potassium into the cell, with the probable concomitant uptake of protons (symport system); Belongs to the HAK/KUP transporter (TC 2.A.72) family.


ensembl_gene_id: ETA_12210
symbol: cinA
gene_biotype: protein_coding
description:
  Putative nucleotide-utilizing enzyme related to molybdopterin-biosynthesis; silverDB:etchr01212; Belongs to the CinA family.


ensembl_gene_id: ETA_12240
symbol: nrdA
gene_biotype: protein_coding
description:
  Ribonucleoside-diphosphate reductase 1 alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.


ensembl_gene_id: ETA_12250
symbol: ubiG
gene_biotype: protein_coding
description:
  3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family.


ensembl_gene_id: ETA_12260
symbol: gyrA
gene_biotype: protein_coding
description:
  DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.


ensembl_gene_id: ETA_12290
symbol: rcsC
gene_biotype: protein_coding
description:
  Sensor kinase protein (Capsular synthesis regulator component C); Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane- associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB.


ensembl_gene_id: ETA_12300
symbol: rcsB
gene_biotype: protein_coding
description:
  Regulator of capsule synthesis B component; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsB is the response regulator that binds to regulatory DNA regions.


ensembl_gene_id: ETA_12310
symbol: yojN
gene_biotype: protein_coding
description:
  Putative sensor kinase in regulatory system; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB.


ensembl_gene_id: ETA_12330
symbol: apbE
gene_biotype: protein_coding
description:
  Putative thiamine biosynthesis lipoprotein; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. Belongs to the ApbE family.


ensembl_gene_id: ETA_12460
symbol: fldB
gene_biotype: protein_coding
description:
  Flavodoxin 2; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family.


ensembl_gene_id: ETA_12500
symbol: ETA_12500
gene_biotype: protein_coding
description:
  L-sorbosone dehydrogenase, NAD(P) dependent; silverDB:etchr01241; Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: ETA_12520
symbol: ETA_12520
gene_biotype: protein_coding
description:
  Acetyl-CoA:acetoacetyl-CoA transferase a subunit; CoA transferase having broad substrate specificity for short- chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons. Belongs to the 3-oxoacid CoA-transferase family.


ensembl_gene_id: ETA_12600
symbol: rplY
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family.


ensembl_gene_id: ETA_12620
symbol: rsuA
gene_biotype: protein_coding
description:
  Ribosomal small subunit pseudouridine synthase A; silverDB:etchr01252; Belongs to the pseudouridine synthase RsuA family.


ensembl_gene_id: ETA_12710
symbol: lpxT
gene_biotype: protein_coding
description:
  Putative membrane-bound phosphatase; Involved in the modification of the lipid A domain of lipopolysaccharides (LPS). Transfers a phosphate group from undecaprenyl pyrophosphate (C55-PP) to lipid A to form lipid A 1- diphosphate. Contributes to the recycling of undecaprenyl phosphate (C55-P); Belongs to the LpxT phosphotransferase family.


ensembl_gene_id: ETA_12770
symbol: nfo
gene_biotype: protein_coding
description:
  Endodeoxyribonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.


ensembl_gene_id: ETA_12790
symbol: yeiE
gene_biotype: protein_coding
description:
  Transcriptional regulator YeiE; silverDB:etchr01269; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: ETA_12810
symbol: ETA_12810
gene_biotype: protein_coding
description:
  FecCD-family membrane transport protein; silverDB:etchr01271; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: ETA_12850
symbol: adhC
gene_biotype: protein_coding
description:
  Alcohol dehydrogenase class III; silverDB:etchr01275; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.


ensembl_gene_id: ETA_12860
symbol: ETA_12860
gene_biotype: protein_coding
description:
  LysR-family transcriptional regulatory protein; silverDB:etchr01276; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: ETA_12910
symbol: mglB
gene_biotype: protein_coding
description:
  Periplasmic D-galactose-binding ABC transport protein (Galactose-binding protein); silverDB:etchr01281.


ensembl_gene_id: ETA_12930
symbol: ETA_12930
gene_biotype: protein_coding
description:
  Galactoside ABC transporter permease component; silverDB:etchr01283; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: ETA_12960
symbol: cdd
gene_biotype: protein_coding
description:
  Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.


ensembl_gene_id: ETA_12990
symbol: metG
gene_biotype: protein_coding
description:
  Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.


ensembl_gene_id: ETA_13000
symbol: mrp
gene_biotype: protein_coding
description:
  Predicted ATPase; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.


ensembl_gene_id: ETA_13050
symbol: ETA_13050
gene_biotype: protein_coding
description:
  Diacylglycerol kinase; Probably phosphorylates lipids; the in vivo substrate is unknown; Belongs to the diacylglycerol/lipid kinase family. YegS lipid kinase subfamily.


ensembl_gene_id: ETA_13100
symbol: mdtC
gene_biotype: protein_coding
description:
  Multidrug resistance protein; silverDB:etchr01300; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtC subfamily.


ensembl_gene_id: ETA_13110
symbol: mdtB
gene_biotype: protein_coding
description:
  Multidrug resistance protein; silverDB:etchr01301; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtB subfamily.


ensembl_gene_id: ETA_13120
symbol: mdtA
gene_biotype: protein_coding
description:
  Multidrug resistance protein; silverDB:etchr01302; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: ETA_13230
symbol: cpsI
gene_biotype: protein_coding
description:
  Probable protein-tyrosine-phosphatase; silverDB:etchr01313; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.


ensembl_gene_id: ETA_13340
symbol: galE
gene_biotype: protein_coding
description:
  UDP-glucose 4-epimerase; silverDB:etchr01324; Belongs to the NAD(P)-dependent epimerase/dehydratase family.


ensembl_gene_id: ETA_13350
symbol: rffG
gene_biotype: protein_coding
description:
  DTDP-glucose 4,6-dehydratase; silverDB:etchr01325; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.


ensembl_gene_id: ETA_13360
symbol: rffH
gene_biotype: protein_coding
description:
  Glucose-1-phosphate thymidylyltransferase (dTDP-glucose pyrophosphorylase); Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.


ensembl_gene_id: ETA_13450
symbol: gnd
gene_biotype: protein_coding
description:
  Gluconate-6-phosphate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.


ensembl_gene_id: ETA_13490
symbol: hisI
gene_biotype: protein_coding
description:
  Histidine biosynthesis bifunctional protein; silverDB:etchr01339; In the N-terminal section; belongs to the PRA-CH family.


ensembl_gene_id: ETA_13500
symbol: hisF
gene_biotype: protein_coding
description:
  Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.


ensembl_gene_id: ETA_13510
symbol: hisA
gene_biotype: protein_coding
description:
  1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; silverDB:etchr01341.


ensembl_gene_id: ETA_13520
symbol: hisH
gene_biotype: protein_coding
description:
  Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.


ensembl_gene_id: ETA_13530
symbol: hisB-2
gene_biotype: protein_coding
description:
  Histidine biosynthesis bifunctional protein HisB; silverDB:etchr01343; In the N-terminal section; belongs to the histidinol- phosphatase family.


ensembl_gene_id: ETA_13540
symbol: hisC
gene_biotype: protein_coding
description:
  Histidinol-phosphate aminotransferase; silverDB:etchr01344; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.


ensembl_gene_id: ETA_13550
symbol: hisD
gene_biotype: protein_coding
description:
  Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.


ensembl_gene_id: ETA_13560
symbol: hisG
gene_biotype: protein_coding
description:
  ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.


ensembl_gene_id: ETA_13630
symbol: dacD
gene_biotype: protein_coding
description:
  Penicillin-binding protein 6B precursor (D-alanyl-D-alanine carboxypeptidase); silverDB:etchr01353; Belongs to the peptidase S11 family.


ensembl_gene_id: ETA_13720
symbol: amn
gene_biotype: protein_coding
description:
  AMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.


ensembl_gene_id: ETA_13780
symbol: rbsA-2
gene_biotype: protein_coding
description:
  Sugar ABC transporter, ATP-binding protein; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family.


ensembl_gene_id: ETA_13790
symbol: ETA_13790
gene_biotype: protein_coding
description:
  Sugar ABC transporter, permease protein; silverDB:etchr01369; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: ETA_13810
symbol: nac
gene_biotype: protein_coding
description:
  Nitrogen assimilation regulatory protein; silverDB:etchr01371; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: ETA_13820
symbol: cbl
gene_biotype: protein_coding
description:
  Transcriptional regulator cys regulon; silverDB:etchr01372; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: ETA_13940
symbol: ETA_13940
gene_biotype: protein_coding
description:
  ABC transporter, ATP-binding protein; silverDB:etchr01384; Belongs to the ABC transporter superfamily.


ensembl_gene_id: ETA_14070
symbol: sitA
gene_biotype: protein_coding
description:
  Iron transport protein, periplasmic-binding protein; silverDB:etchr01397; Belongs to the bacterial solute-binding protein 9 family.


ensembl_gene_id: ETA_14080
symbol: katG
gene_biotype: protein_coding
description:
  Peroxidase/catalase HPI; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily.


ensembl_gene_id: ETA_14100
symbol: mtfA-2
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Involved in the regulation of ptsG expression by binding and inactivating Mlc.


ensembl_gene_id: ETA_14130
symbol: queH
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).


ensembl_gene_id: ETA_14150
symbol: vsr
gene_biotype: protein_coding
description:
  DNA mismatch endonuclease, patch repair protein; May nick specific sequences that contain T:G mispairs resulting from m5C-deamination.


ensembl_gene_id: ETA_14230
symbol: fliD
gene_biotype: protein_coding
description:
  Flagellar hook-associated protein 2; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.


ensembl_gene_id: ETA_14240
symbol: fliC
gene_biotype: protein_coding
description:
  Flagellin; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.


ensembl_gene_id: ETA_14260
symbol: fliA
gene_biotype: protein_coding
description:
  RNA polymerase sigma factor for flagellar operon; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily.


ensembl_gene_id: ETA_14300
symbol: putA
gene_biotype: protein_coding
description:
  Bifunctional protein dehydrogenase/ delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family.  In the N-terminal section; belongs to the proline dehydrogenase family.


ensembl_gene_id: ETA_14310
symbol: putP
gene_biotype: protein_coding
description:
  Sodium/proline symporter (Proline permease); Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: ETA_14340
symbol: ycdB
gene_biotype: protein_coding
description:
  Conserved hypothetical protein YcdB; Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the tetrapyrrol ring intact. Belongs to the DyP-type peroxidase family.


ensembl_gene_id: ETA_14450
symbol: ETA_14450
gene_biotype: protein_coding
description:
  Cytosine/purines/uracil/thiamine/allantoin permease family protein; silverDB:etchr01435; Belongs to the purine-cytosine permease (2.A.39) family.


ensembl_gene_id: ETA_14540
symbol: ETA_14540
gene_biotype: protein_coding
description:
  Regulatory protein, LysR; silverDB:etchr01444; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: ETA_14580
symbol: flhD
gene_biotype: protein_coding
description:
  Flagellar transcriptional activator FlhD; Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhD family.


ensembl_gene_id: ETA_14590
symbol: flhC
gene_biotype: protein_coding
description:
  Regulator of flagellar biosynthesis FlhC; Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhC family.


ensembl_gene_id: ETA_14680
symbol: cheR
gene_biotype: protein_coding
description:
  Chemotaxis protein methyltransferase; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.


ensembl_gene_id: ETA_14690
symbol: cheB
gene_biotype: protein_coding
description:
  Chemotaxis response regulator protein-glutamate methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.


ensembl_gene_id: ETA_14700
symbol: cheY
gene_biotype: protein_coding
description:
  Chemotaxis regulator transmits chemoreceptor signals to flagelllar motor components; silverDB:etchr01460.


ensembl_gene_id: ETA_14710
symbol: cheZ
gene_biotype: protein_coding
description:
  Chemotaxis protein; Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).


ensembl_gene_id: ETA_14720
symbol: flhB
gene_biotype: protein_coding
description:
  Flagellar biosynthesis protein FlhB; Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the type III secretion exporter family.


ensembl_gene_id: ETA_14730
symbol: flhA
gene_biotype: protein_coding
description:
  Flagellar biosynthesis protein FlhA; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.


ensembl_gene_id: ETA_14780
symbol: cutC
gene_biotype: protein_coding
description:
  Copper homeostasis protein; Participates in the control of copper homeostasis. Belongs to the CutC family.


ensembl_gene_id: ETA_14800
symbol: yecP
gene_biotype: protein_coding
description:
  Putative enzyme YecP; Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L- methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5- carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.


ensembl_gene_id: ETA_14810
symbol: yecO
gene_biotype: protein_coding
description:
  Conserved hypothetical protein YecO; Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).


ensembl_gene_id: ETA_14850
symbol: aspS
gene_biotype: protein_coding
description:
  Aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.


ensembl_gene_id: ETA_14880
symbol: ruvC
gene_biotype: protein_coding
description:
  Crossover junction endodeoxyribonuclease; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.


ensembl_gene_id: ETA_14890
symbol: ruvA
gene_biotype: protein_coding
description:
  Holliday junction ATP-dependent DNA helicase; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.


ensembl_gene_id: ETA_14900
symbol: ruvB
gene_biotype: protein_coding
description:
  Holliday junction ATP-dependent DNA helicase; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.


ensembl_gene_id: ETA_14920
symbol: znuC
gene_biotype: protein_coding
description:
  ABC superfamily (Atp_bind) high affinity Zn transport protein; Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family.


ensembl_gene_id: ETA_14950
symbol: msbB
gene_biotype: protein_coding
description:
  Suppressor of htrB, heat shock protein; Catalyzes the transfer of myristate from myristoyl-acyl carrier protein (ACP) to Kdo(2)-(lauroyl)-lipid IV(A) to form Kdo(2)- lipid A.


ensembl_gene_id: ETA_14980
symbol: zwf
gene_biotype: protein_coding
description:
  Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.


ensembl_gene_id: ETA_14990
symbol: purT
gene_biotype: protein_coding
description:
  Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family.


ensembl_gene_id: ETA_15110
symbol: yebU
gene_biotype: protein_coding
description:
  Conserved hypothetical protein YebU; Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA.


ensembl_gene_id: ETA_15150
symbol: proQ
gene_biotype: protein_coding
description:
  ProP effector; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities. May regulate ProP activity through an RNA-based, post-transcriptional mechanism. Belongs to the ProQ family.


ensembl_gene_id: ETA_15250
symbol: sdaA
gene_biotype: protein_coding
description:
  L-serine dehydratase 1; silverDB:etchr01515; Belongs to the iron-sulfur dependent L-serine dehydratase family.


ensembl_gene_id: ETA_15340
symbol: rnd
gene_biotype: protein_coding
description:
  Ribonuclease D; Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides; Belongs to the RNase D family.


ensembl_gene_id: ETA_15350
symbol: minE
gene_biotype: protein_coding
description:
  Cell division topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.


ensembl_gene_id: ETA_15370
symbol: minC
gene_biotype: protein_coding
description:
  Septum site-determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family.


ensembl_gene_id: ETA_15410
symbol: dsbB
gene_biotype: protein_coding
description:
  Disulfide bond formation protein B; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family.


ensembl_gene_id: ETA_15440
symbol: dadA
gene_biotype: protein_coding
description:
  D-amino acid dehydrogenase small subunit; Oxidative deamination of D-amino acids; Belongs to the DadA oxidoreductase family.


ensembl_gene_id: ETA_15450
symbol: dadB
gene_biotype: protein_coding
description:
  Alanine racemase, catabolic; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.


ensembl_gene_id: ETA_15480
symbol: cvrA
gene_biotype: protein_coding
description:
  Cell volume regulation protein A; K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. NhaP2 subfamily.


ensembl_gene_id: ETA_15520
symbol: ETA_15520
gene_biotype: protein_coding
description:
  Short-chain dehydrogenase/reductase SDR; silverDB:etchr01542; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: ETA_15530
symbol: ETA_15530
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; silverDB:etchr01543; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: ETA_15580
symbol: ETA_15580
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; silverDB:etchr01548; Belongs to the glucose-6-phosphate 1-epimerase family.


ensembl_gene_id: ETA_15590
symbol: gapA
gene_biotype: protein_coding
description:
  Glyceraldehyde 3-phosphate dehydrogenase A; silverDB:etchr01549; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.


ensembl_gene_id: ETA_15610
symbol: msrB
gene_biotype: protein_coding
description:
  Methionine sulfoxide reductase B; silverDB:etchr01551; Belongs to the MsrB Met sulfoxide reductase family.


ensembl_gene_id: ETA_15670
symbol: topB
gene_biotype: protein_coding
description:
  DNA topoisomerase III; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA su [...]


ensembl_gene_id: ETA_15730
symbol: purU
gene_biotype: protein_coding
description:
  Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).


ensembl_gene_id: ETA_15750
symbol: rssB
gene_biotype: protein_coding
description:
  Putative RssB protein; Regulates the turnover of the sigma S factor (RpoS) by promoting its proteolysis in exponentially growing cells. Acts by binding and delivering RpoS to the ClpXP protease. RssB is not co- degraded with RpoS, but is released from the complex and can initiate a new cycle of RpoS recognition and degradation.


ensembl_gene_id: ETA_15810
symbol: adhE
gene_biotype: protein_coding
description:
  Aldehyde-alcohol dehydrogenase; silverDB:etchr01571; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.


ensembl_gene_id: ETA_15870
symbol: oppD
gene_biotype: protein_coding
description:
  ATP-binding protein of oligopeptide ABC transport system; silverDB:etchr01577; Belongs to the ABC transporter superfamily.


ensembl_gene_id: ETA_15880
symbol: oppF
gene_biotype: protein_coding
description:
  ATP-binding protein of oligopeptide ABC transport system; silverDB:etchr01578; Belongs to the ABC transporter superfamily.


ensembl_gene_id: ETA_15900
symbol: cls
gene_biotype: protein_coding
description:
  Cardiolipin synthetase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.


ensembl_gene_id: ETA_15930
symbol: tonB
gene_biotype: protein_coding
description:
  Periplasmic protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.


ensembl_gene_id: ETA_15950
symbol: ispZ
gene_biotype: protein_coding
description:
  Probable intracellular septation protein; Involved in cell division; probably involved in intracellular septation; Belongs to the YciB family.


ensembl_gene_id: ETA_15990
symbol: trpA
gene_biotype: protein_coding
description:
  Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.


ensembl_gene_id: ETA_16000
symbol: trpB
gene_biotype: protein_coding
description:
  Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.


ensembl_gene_id: ETA_16020
symbol: trpD
gene_biotype: protein_coding
description:
  Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).


ensembl_gene_id: ETA_16100
symbol: rluB
gene_biotype: protein_coding
description:
  Ribosomal large subunit pseudouridine synthase B; silverDB:etchr01600; Belongs to the pseudouridine synthase RsuA family.


ensembl_gene_id: ETA_16130
symbol: topA
gene_biotype: protein_coding
description:
  DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]


ensembl_gene_id: ETA_16140
symbol: cysB
gene_biotype: protein_coding
description:
  HTH-type transcriptional regulator CysB; silverDB:etchr01604; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: ETA_16170
symbol: ribA
gene_biotype: protein_coding
description:
  GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.


ensembl_gene_id: ETA_16190
symbol: lapA
gene_biotype: protein_coding
description:
  Conserved hypothetical protein (DUF1049); Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family.


ensembl_gene_id: ETA_16200
symbol: lapB
gene_biotype: protein_coding
description:
  Predicted N-acetylglucosaminyl transferase, similar to conserved hypothetical protein YciM; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane; Belongs to the LapB family.


ensembl_gene_id: ETA_16210
symbol: pyrF
gene_biotype: protein_coding
description:
  Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.


ensembl_gene_id: ETA_16280
symbol: rnb
gene_biotype: protein_coding
description:
  Exoribonuclease II; Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction.


ensembl_gene_id: ETA_16290
symbol: ETA_16290
gene_biotype: protein_coding
description:
  Putative molybdopterin oxidoreductase; silverDB:etchr01619; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: ETA_16300
symbol: ETA_16300
gene_biotype: protein_coding
description:
  LysR-family transcriptional regulator; silverDB:etchr01620; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: ETA_16330
symbol: sapD
gene_biotype: protein_coding
description:
  Peptide transport system ATP-binding protein; silverDB:etchr01623; Belongs to the ABC transporter superfamily.


ensembl_gene_id: ETA_16460
symbol: tpx
gene_biotype: protein_coding
description:
  Thiol peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily.


ensembl_gene_id: ETA_16550
symbol: ttcA
gene_biotype: protein_coding
description:
  Predicted ATPase of the PP-loop superfamily; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.


ensembl_gene_id: ETA_16560
symbol: dbpA
gene_biotype: protein_coding
description:
  ATP-dependent RNA helicase; DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes.


ensembl_gene_id: ETA_16590
symbol: ldhA
gene_biotype: protein_coding
description:
  D-lactate dehydrogenase; silverDB:etchr01649; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: ETA_16640
symbol: ETA_16640
gene_biotype: protein_coding
description:
  Sugar ABC transporter permease component; silverDB:etchr01654; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: ETA_16700
symbol: acpD
gene_biotype: protein_coding
description:
  Acyl carrier protein phosphodiesterase; Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity; Belongs to the azoreductase type 1 family.


ensembl_gene_id: ETA_16900
symbol: ETA_16900
gene_biotype: protein_coding
description:
  Putative carboxylesterase; silverDB:etchr01680; Belongs to the type-B carboxylesterase/lipase family.


ensembl_gene_id: ETA_16940
symbol: pepT
gene_biotype: protein_coding
description:
  Peptidase T; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family.


ensembl_gene_id: ETA_16970
symbol: sotB
gene_biotype: protein_coding
description:
  Putative sugar efflux transporter; Involved in the efflux of sugars. The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites; Belongs to the major facilitator superfamily. SotB (TC 2.A.1.2) family.


ensembl_gene_id: ETA_17100
symbol: ETA_17100
gene_biotype: protein_coding
description:
  Carbonate dehydratase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family.


ensembl_gene_id: ETA_17180
symbol: nasA
gene_biotype: protein_coding
description:
  Nitrate reductase; silverDB:etchr01707; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.


ensembl_gene_id: ETA_17190
symbol: nasB
gene_biotype: protein_coding
description:
  Nitrite reductase [NAD(P)H] large subunit; silverDB:etchr01708; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.


ensembl_gene_id: ETA_17320
symbol: ETA_17320
gene_biotype: protein_coding
description:
  LysR-family transcriptional regulator; silverDB:etchr01721; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: ETA_17430
symbol: fabV
gene_biotype: protein_coding
description:
  Putative short-chain alcohol dehydrogenase; Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon- carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP); Belongs to the TER reductase family.


ensembl_gene_id: ETA_17500
symbol: guaD
gene_biotype: protein_coding
description:
  Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.


ensembl_gene_id: ETA_17510
symbol: ydfG
gene_biotype: protein_coding
description:
  NADP-dependent L-serine/L-allo-threonine dehydrogenase YdfG; silverDB:etchr01740; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: ETA_17560
symbol: ETA_17560
gene_biotype: protein_coding
description:
  LysR-family transcriptional regulator; silverDB:etchr01745; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: ETA_17570
symbol: bioD-2
gene_biotype: protein_coding
description:
  Probable dethiobiotin synthetase 2; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. Belongs to the dethiobiotin synthetase family.


ensembl_gene_id: ETA_17590
symbol: ynfL
gene_biotype: protein_coding
description:
  Putative transcriptional regulator, LysR family; silverDB:etchr01748; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: ETA_17630
symbol: fumC
gene_biotype: protein_coding
description:
  Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.


ensembl_gene_id: ETA_17650
symbol: add
gene_biotype: protein_coding
description:
  Adenosine deaminase; silverDB:etchr01754; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.


ensembl_gene_id: ETA_17680
symbol: araH
gene_biotype: protein_coding
description:
  High-affinity L-arabinose transport system membrane protein; silverDB:etchr01757; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: ETA_17690
symbol: araG
gene_biotype: protein_coding
description:
  L-arabinose transport ATP-binding protein; Part of the ABC transporter complex AraFGH involved in arabinose import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Arabinose importer (TC 3.A.1.2.2) family.


ensembl_gene_id: ETA_17740
symbol: rnfA
gene_biotype: protein_coding
description:
  Electron transport complex protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.


ensembl_gene_id: ETA_17750
symbol: rnfB
gene_biotype: protein_coding
description:
  Electron transport complex protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.


ensembl_gene_id: ETA_17760
symbol: rnfC
gene_biotype: protein_coding
description:
  Electron transport complex protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.


ensembl_gene_id: ETA_17770
symbol: rnfD
gene_biotype: protein_coding
description:
  Electron transport complex protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the NqrB/RnfD family.


ensembl_gene_id: ETA_17780
symbol: rnfG
gene_biotype: protein_coding
description:
  Electron transport complex protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the RnfG family.


ensembl_gene_id: ETA_17800
symbol: nth
gene_biotype: protein_coding
description:
  Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.


ensembl_gene_id: ETA_17810
symbol: betA
gene_biotype: protein_coding
description:
  Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.


ensembl_gene_id: ETA_17820
symbol: betB
gene_biotype: protein_coding
description:
  Betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid.


ensembl_gene_id: ETA_17840
symbol: tppB
gene_biotype: protein_coding
description:
  Tripeptide permease; Proton-dependent permease that transports di- and tripeptides; Belongs to the PTR2/POT transporter (TC 2.A.17) family. DtpA subfamily.


ensembl_gene_id: ETA_17860
symbol: pdxY
gene_biotype: protein_coding
description:
  Pyridoxamine kinase; Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP.


ensembl_gene_id: ETA_17870
symbol: tyrS
gene_biotype: protein_coding
description:
  Tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.


ensembl_gene_id: ETA_17880
symbol: pdxH
gene_biotype: protein_coding
description:
  Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).


ensembl_gene_id: ETA_17890
symbol: ydhH
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family.


ensembl_gene_id: ETA_17910
symbol: slyA
gene_biotype: protein_coding
description:
  Transcriptional regulator for cryptic hemolysin; Transcription regulator that can specifically activate or repress expression of target genes; Belongs to the SlyA family.


ensembl_gene_id: ETA_17930
symbol: ydhJ
gene_biotype: protein_coding
description:
  Conserved hypothetical protein YdhJ; silverDB:etchr01782; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: ETA_17970
symbol: ETA_17970
gene_biotype: protein_coding
description:
  Putative transcriptional regulator, LysR; silverDB:etchr01786; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: ETA_18030
symbol: rnt
gene_biotype: protein_coding
description:
  Ribonuclease T; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.


ensembl_gene_id: ETA_18040
symbol: ydhD
gene_biotype: protein_coding
description:
  Putative glutaredoxin protein; silverDB:etchr01793; Belongs to the glutaredoxin family. Monothiol subfamily.


ensembl_gene_id: ETA_18060
symbol: purR
gene_biotype: protein_coding
description:
  HTH-type transcriptional repressor PurR (Purine nucleotide synthesis repressor); Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression.


ensembl_gene_id: ETA_18070
symbol: ydhB
gene_biotype: protein_coding
description:
  LysR-family transcriptional regulatory YdhB; silverDB:etchr01796; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: ETA_18160
symbol: sufS
gene_biotype: protein_coding
description:
  Cysteine desulfurase; Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation. Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L- selenocysteine. Selenocysteine lyase activity is however unsure in vivo.


ensembl_gene_id: ETA_18200
symbol: sufA
gene_biotype: protein_coding
description:
  Iron-sulfur cluster assembly scaffold protein; silverDB:etchr01809; Belongs to the HesB/IscA family.


ensembl_gene_id: ETA_18240
symbol: ppsA
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.


ensembl_gene_id: ETA_18250
symbol: ydiA
gene_biotype: protein_coding
description:
  Conserved hypothetical protein YdiA; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.


ensembl_gene_id: ETA_18260
symbol: aroH
gene_biotype: protein_coding
description:
  Phospho-2-dehydro-3-deoxyheptonate aldolase, Trp-sensitive; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP).


ensembl_gene_id: ETA_18290
symbol: hmuU
gene_biotype: protein_coding
description:
  Hemin transport system permease protein; silverDB:etchr01818; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: ETA_18300
symbol: hmuV
gene_biotype: protein_coding
description:
  Hemin transport system ATP-binding protein; Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system.


ensembl_gene_id: ETA_18310
symbol: ydiU
gene_biotype: protein_coding
description:
  Conserved hypothetical protein YdiU; Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).


ensembl_gene_id: ETA_18340
symbol: btuE
gene_biotype: protein_coding
description:
  Glutathione peroxidase; Non-specific peroxidase that can use thioredoxin or glutathione as a reducing agent.


ensembl_gene_id: ETA_18350
symbol: ihfA
gene_biotype: protein_coding
description:
  Integration host factor alpha-subunit (IHF-alpha); This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.


ensembl_gene_id: ETA_18360
symbol: pheT
gene_biotype: protein_coding
description:
  Phenylalanyl-tRNA synthetase beta chain; silverDB:etchr01825; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.


ensembl_gene_id: ETA_18370
symbol: pheS
gene_biotype: protein_coding
description:
  Phenylalanyl-tRNA synthetase alpha chain; silverDB:etchr01826; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.


ensembl_gene_id: ETA_18380
symbol: rplT
gene_biotype: protein_coding
description:
  50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.


ensembl_gene_id: ETA_18390
symbol: rpmI
gene_biotype: protein_coding
description:
  50S ribosomal protein L35; silverDB:etchr01828; Belongs to the bacterial ribosomal protein bL35 family.


ensembl_gene_id: ETA_18400
symbol: infC
gene_biotype: protein_coding
description:
  Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.


ensembl_gene_id: ETA_18410
symbol: thrS
gene_biotype: protein_coding
description:
  Threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).


ensembl_gene_id: ETA_18480
symbol: ydjN
gene_biotype: protein_coding
description:
  Putative symporter YdjN; silverDB:etchr01837; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: ETA_18510
symbol: nadE
gene_biotype: protein_coding
description:
  NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.


ensembl_gene_id: ETA_18550
symbol: astE
gene_biotype: protein_coding
description:
  Succinylglutamate desuccinylase; Transforms N(2)-succinylglutamate into succinate and glutamate; Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.


ensembl_gene_id: ETA_18560
symbol: astB
gene_biotype: protein_coding
description:
  Succinylarginine dihydrolase; Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)- succinylornithine, ammonia and CO(2).


ensembl_gene_id: ETA_18570
symbol: astD
gene_biotype: protein_coding
description:
  N-succinylglutamate 5-semialdehyde dehydrogenase; Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.


ensembl_gene_id: ETA_18580
symbol: astA
gene_biotype: protein_coding
description:
  Arginine N-succinyltransferase; Catalyzes the transfer of succinyl-CoA to arginine to produce N(2)-succinylarginine.


ensembl_gene_id: ETA_18590
symbol: argM
gene_biotype: protein_coding
description:
  Succinylornithine transaminase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.


ensembl_gene_id: ETA_18670
symbol: chaC
gene_biotype: protein_coding
description:
  Cation transport protein; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.


ensembl_gene_id: ETA_18780
symbol: hemK
gene_biotype: protein_coding
description:
  Protein methyltransferase; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.


ensembl_gene_id: ETA_18790
symbol: prfA
gene_biotype: protein_coding
description:
  Peptide chain release factor 1 (RF-1); Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.


ensembl_gene_id: ETA_18800
symbol: hemA
gene_biotype: protein_coding
description:
  Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).


ensembl_gene_id: ETA_18810
symbol: lolB
gene_biotype: protein_coding
description:
  Outer membrane lipoprotein LolB; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.


ensembl_gene_id: ETA_18820
symbol: ispE
gene_biotype: protein_coding
description:
  4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol; Belongs to the GHMP kinase family. IspE subfamily.


ensembl_gene_id: ETA_18830
symbol: prs
gene_biotype: protein_coding
description:
  Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.


ensembl_gene_id: ETA_18850
symbol: pth
gene_biotype: protein_coding
description:
  Peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.


ensembl_gene_id: ETA_18870
symbol: engD
gene_biotype: protein_coding
description:
  Putative GTP-binding protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.


ensembl_gene_id: ETA_19250
symbol: ETA_19250
gene_biotype: protein_coding
description:
  Putative thiamine biosynthesis protein; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. Belongs to the ApbE family.


ensembl_gene_id: ETA_19270
symbol: ygjE
gene_biotype: protein_coding
description:
  Putative tartrate carrier (Tartrate transporter) (Tartrate/succinate antiporter); silverDB:etchr01916.


ensembl_gene_id: ETA_19280
symbol: fumA
gene_biotype: protein_coding
description:
  Fumarase A; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.


ensembl_gene_id: ETA_19320
symbol: argC
gene_biotype: protein_coding
description:
  N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 2 subfamily.


ensembl_gene_id: ETA_19330
symbol: treA
gene_biotype: protein_coding
description:
  Periplasmic trehalase; Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system; Belongs to the glycosyl hydrolase 37 family.


ensembl_gene_id: ETA_19350
symbol: ycgR-2
gene_biotype: protein_coding
description:
  Putative inner membrane protein; Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility.


ensembl_gene_id: ETA_19500
symbol: rluE
gene_biotype: protein_coding
description:
  Ribosomal large subunit pseudouridine synthase E; silverDB:etchr01939; Belongs to the pseudouridine synthase RsuA family.


ensembl_gene_id: ETA_19660
symbol: nudJ
gene_biotype: protein_coding
description:
  Putative MutT family protein; silverDB:etchr01955; Belongs to the Nudix hydrolase family. NudJ subfamily.


ensembl_gene_id: ETA_19670
symbol: trmU
gene_biotype: protein_coding
description:
  tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln), leading to the formation of s(2)U34, the first step of tRNA-mnm(5)s(2)U34 synthesis. Sulfur is provided by IscS, via a sulfur-relay system. Binds ATP and its substrate tRNAs; Belongs to the MnmA/TRMU family.


ensembl_gene_id: ETA_19690
symbol: purB
gene_biotype: protein_coding
description:
  Adenylosuccinate lyase; silverDB:etchr01958; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.


ensembl_gene_id: ETA_19760
symbol: ycfX
gene_biotype: protein_coding
description:
  Putative NAGC-like transcriptional regulator YcfX; Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P.


ensembl_gene_id: ETA_19780
symbol: lolD
gene_biotype: protein_coding
description:
  Lipoprotein-releasing system ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.


ensembl_gene_id: ETA_19790
symbol: ETA_19790
gene_biotype: protein_coding
description:
  ABC-type transport system, involved in lipoprotein release, permease component; silverDB:etchr01968.


ensembl_gene_id: ETA_19880
symbol: fliF
gene_biotype: protein_coding
description:
  Flagellar basal-body M-ring protein; The M ring may be actively involved in energy transduction. Belongs to the FliF family.


ensembl_gene_id: ETA_19890
symbol: fliG
gene_biotype: protein_coding
description:
  Flagellar motor switch protein FliG; FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.


ensembl_gene_id: ETA_19920
symbol: fliJ
gene_biotype: protein_coding
description:
  Flagellar biosynthesis protein FliJ; Flagellar protein that affects chemotactic events. Belongs to the FliJ family.


ensembl_gene_id: ETA_19940
symbol: fliL
gene_biotype: protein_coding
description:
  Flagellar fliL protein; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.


ensembl_gene_id: ETA_19950
symbol: fliM
gene_biotype: protein_coding
description:
  Flagellar motor switch protein; FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.


ensembl_gene_id: ETA_19960
symbol: fliN
gene_biotype: protein_coding
description:
  Flagellar motor switch protein; FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliN/MopA/SpaO family.


ensembl_gene_id: ETA_19980
symbol: fliP
gene_biotype: protein_coding
description:
  Flagellar biosynthesis protein; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family.


ensembl_gene_id: ETA_20000
symbol: fliR
gene_biotype: protein_coding
description:
  Flagellar biosynthesis protein; Role in flagellar biosynthesis. Belongs to the FliR/MopE/SpaR family.


ensembl_gene_id: ETA_20010
symbol: rcsA
gene_biotype: protein_coding
description:
  Colanic acid capsular biosynthesis activation protein A; Component of the Rcs signaling system, which controls transcription of numerous genes. Binds to DNA to regulate expression of genes.


ensembl_gene_id: ETA_20060
symbol: mfd
gene_biotype: protein_coding
description:
  Transcription-repair coupling factor (ATP-dependent helicase mfd); Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.


ensembl_gene_id: ETA_20090
symbol: nagZ
gene_biotype: protein_coding
description:
  Beta-hexosaminidase (N-acetyl-beta-glucosaminidase); Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.


ensembl_gene_id: ETA_20110
symbol: lpoB
gene_biotype: protein_coding
description:
  Putative lipoprotein; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b). Belongs to the LpoB family.


ensembl_gene_id: ETA_20170
symbol: tmk
gene_biotype: protein_coding
description:
  Thymidylate kinase (dTMP kinase); Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.


ensembl_gene_id: ETA_20180
symbol: mltG
gene_biotype: protein_coding
description:
  Probable aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.


ensembl_gene_id: ETA_20200
symbol: fabF
gene_biotype: protein_coding
description:
  3-oxoacyl-[acyl-carrier-protein] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.


ensembl_gene_id: ETA_20210
symbol: acpP
gene_biotype: protein_coding
description:
  Probable acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.


ensembl_gene_id: ETA_20220
symbol: fabG
gene_biotype: protein_coding
description:
  3-oxoacyl-[acyl-carrier-protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: ETA_20240
symbol: fabH
gene_biotype: protein_coding
description:
  3-oxoacyl-[acyl-carrier-protein] synthase 3; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.


ensembl_gene_id: ETA_20250
symbol: plsX
gene_biotype: protein_coding
description:
  Fatty acid/phospholipid synthesis protein; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.


ensembl_gene_id: ETA_20280
symbol: yceF
gene_biotype: protein_coding
description:
  Conserved hypothetical protein YceF; Nucleoside triphosphate pyrophosphatase that hydrolyzes 7- methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids; Belongs to the Maf family. YceF subfamily.


ensembl_gene_id: ETA_20290
symbol: rluC
gene_biotype: protein_coding
description:
  23S rRNA pseudouridylate synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.


ensembl_gene_id: ETA_20300
symbol: ams
gene_biotype: protein_coding
description:
  Ribonuclease E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily.


ensembl_gene_id: ETA_20340
symbol: flgI
gene_biotype: protein_coding
description:
  Flagellar P-ring protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.


ensembl_gene_id: ETA_20350
symbol: flgH
gene_biotype: protein_coding
description:
  Flagellar L-ring protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.


ensembl_gene_id: ETA_20360
symbol: flgG
gene_biotype: protein_coding
description:
  Flagellar basal-body rod protein; silverDB:etchr02024; Belongs to the flagella basal body rod proteins family.


ensembl_gene_id: ETA_20390
symbol: flgD
gene_biotype: protein_coding
description:
  Flagellar biosynthesis, initiation of hook assembly; Required for flagellar hook formation. May act as a scaffolding protein.


ensembl_gene_id: ETA_20400
symbol: flgC
gene_biotype: protein_coding
description:
  Cell-proximal portion of basal-body rod; silverDB:etchr02028; Belongs to the flagella basal body rod proteins family.


ensembl_gene_id: ETA_20410
symbol: flgB
gene_biotype: protein_coding
description:
  Flagellar basal-body rod protein; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.


ensembl_gene_id: ETA_20420
symbol: flgA
gene_biotype: protein_coding
description:
  Flagellar biosynthesis; Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P- ring assembly; Belongs to the FlgA family.


ensembl_gene_id: ETA_20450
symbol: mviN
gene_biotype: protein_coding
description:
  Virulence factor MviN, possible MOP Superfamliy efflux pump precursor; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.


ensembl_gene_id: ETA_20550
symbol: solA
gene_biotype: protein_coding
description:
  N-methyl-L-tryptophan oxidase; Catalyzes the oxidative demethylation of N-methyl-L- tryptophan; Belongs to the MSOX/MTOX family. MTOX subfamily.


ensembl_gene_id: ETA_20600
symbol: htrB
gene_biotype: protein_coding
description:
  Lipid A biosynthesis lauroyl acyltransferase; Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A).


ensembl_gene_id: ETA_20640
symbol: opgH
gene_biotype: protein_coding
description:
  Glucans biosynthesis glucosyltransferase H; Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).


ensembl_gene_id: ETA_20650
symbol: opgG
gene_biotype: protein_coding
description:
  Periplasmatic glucans biosynthesis protein G; Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).


ensembl_gene_id: ETA_20660
symbol: mdoC
gene_biotype: protein_coding
description:
  Glucans biosynthesis protein C; Necessary for the succinyl substitution of periplasmic glucans. Could catalyze the transfer of succinyl residues from the cytoplasmic side of the membrane to the nascent glucan backbones on the periplasmic side of the membrane.


ensembl_gene_id: ETA_20670
symbol: ymdC
gene_biotype: protein_coding
description:
  Putative phospholipase; Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) from phosphatidylglycerol (PG) and phosphatidylethanolamine (PE); Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsC sub-subfamily.


ensembl_gene_id: ETA_20760
symbol: pgsA
gene_biotype: protein_coding
description:
  tRNA-Gly; This protein catalyzes the committed step to the synthesis of the acidic phospholipids; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: ETA_20770
symbol: uvrC
gene_biotype: protein_coding
description:
  UvrABC system protein C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.


ensembl_gene_id: ETA_20880
symbol: ETA_20880
gene_biotype: protein_coding
description:
  Putative NAD-dependent aldehyde dehydrogenase; silverDB:etchr02076; Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: ETA_20930
symbol: rlmI
gene_biotype: protein_coding
description:
  SAM-dependent methyltransferase; Specifically methylates the cytosine at position 1962 (m5C1962) of 23S rRNA.


ensembl_gene_id: ETA_20940
symbol: hspQ
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress; Belongs to the HspQ family.


ensembl_gene_id: ETA_21020
symbol: sulA
gene_biotype: protein_coding
description:
  Cell division inhibitor; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.


ensembl_gene_id: ETA_21030
symbol: ETA_21030
gene_biotype: protein_coding
description:
  Outer membrane protein A; silverDB:etchr02091; Belongs to the outer membrane OOP (TC 1.B.6) superfamily.


ensembl_gene_id: ETA_21040
symbol: ycbG
gene_biotype: protein_coding
description:
  Conserved hypothetical protein (DUF1047); Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain.


ensembl_gene_id: ETA_21060
symbol: fabA
gene_biotype: protein_coding
description:
  3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.


ensembl_gene_id: ETA_21120
symbol: ycbY
gene_biotype: protein_coding
description:
  Conserved hypothetical protein YcbY; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family.


ensembl_gene_id: ETA_21140
symbol: ycbW
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ.


ensembl_gene_id: ETA_21150
symbol: pyrD
gene_biotype: protein_coding
description:
  Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.


ensembl_gene_id: ETA_21190
symbol: ssuD
gene_biotype: protein_coding
description:
  Alkanesulfonate monooxygenase; Catalyzes the desulfonation of aliphatic sulfonates. Belongs to the SsuD family.


ensembl_gene_id: ETA_21210
symbol: ssuB
gene_biotype: protein_coding
description:
  Putative aliphatic sulfonates transport ATP-binding protein; Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system.


ensembl_gene_id: ETA_21230
symbol: pncB
gene_biotype: protein_coding
description:
  Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family.


ensembl_gene_id: ETA_21300
symbol: mukB
gene_biotype: protein_coding
description:
  Chromosome partition protein; Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division; Belongs to the SMC family. MukB subfamily.


ensembl_gene_id: ETA_21310
symbol: mukE
gene_biotype: protein_coding
description:
  Chromosome partition protein; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF.


ensembl_gene_id: ETA_21320
symbol: mukF
gene_biotype: protein_coding
description:
  Chromosome partition protein; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity.


ensembl_gene_id: ETA_21330
symbol: smtA
gene_biotype: protein_coding
description:
  S-adenosylmethionine-dependent methyltransferase; Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs; Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoM family.


ensembl_gene_id: ETA_21360
symbol: kdsB
gene_biotype: protein_coding
description:
  CTP:CMP-3-deoxy-D-manno-octulosonate transferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.


ensembl_gene_id: ETA_21380
symbol: lpxK
gene_biotype: protein_coding
description:
  Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).


ensembl_gene_id: ETA_21390
symbol: msbA
gene_biotype: protein_coding
description:
  Lipid A export ATP-binding/permease protein; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.


ensembl_gene_id: ETA_21410
symbol: ihfB
gene_biotype: protein_coding
description:
  Integration host factor beta-subunit (IHF-beta); This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.


ensembl_gene_id: ETA_21420
symbol: rpsA
gene_biotype: protein_coding
description:
  30S ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.


ensembl_gene_id: ETA_21440
symbol: aroA
gene_biotype: protein_coding
description:
  3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.


ensembl_gene_id: ETA_21450
symbol: serC
gene_biotype: protein_coding
description:
  Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.


ensembl_gene_id: ETA_21490
symbol: pflA
gene_biotype: protein_coding
description:
  Pyruvate formate lyase activating enzyme 1; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family.


ensembl_gene_id: ETA_21510
symbol: serS
gene_biotype: protein_coding
description:
  Seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).


ensembl_gene_id: ETA_21530
symbol: lolA
gene_biotype: protein_coding
description:
  Outer membrane lipoproteins carrier protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).


ensembl_gene_id: ETA_21590
symbol: aat
gene_biotype: protein_coding
description:
  Leucyl, phenylalanyl-tRNA-protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.


ensembl_gene_id: ETA_21600
symbol: infA
gene_biotype: protein_coding
description:
  Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.


ensembl_gene_id: ETA_21610
symbol: clpA
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease ATP-binding subunit; silverDB:etchr02149; Belongs to the ClpA/ClpB family.


ensembl_gene_id: ETA_21620
symbol: clpS
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease adaptor protein; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family.


ensembl_gene_id: ETA_21690
symbol: artI
gene_biotype: protein_coding
description:
  Arginine-binding periplasmic protein 1; silverDB:etchr02157; Belongs to the bacterial solute-binding protein 3 family.


ensembl_gene_id: ETA_21720
symbol: artJ
gene_biotype: protein_coding
description:
  Arginine-binding periplasmic protein 2; silverDB:etchr02160; Belongs to the bacterial solute-binding protein 3 family.


ensembl_gene_id: ETA_21760
symbol: potG
gene_biotype: protein_coding
description:
  Putrescine transport ATP-binding protein; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.


ensembl_gene_id: ETA_21770
symbol: potF
gene_biotype: protein_coding
description:
  Putrescine-binding periplasmic protein; Required for the activity of the bacterial periplasmic transport system of putrescine; Belongs to the bacterial solute-binding protein PotD/PotF family.


ensembl_gene_id: ETA_21790
symbol: nfsA
gene_biotype: protein_coding
description:
  Oxygen-insensitive NADPH nitroreductase (Modulator of drug activity A); silverDB:etchr02167; Belongs to the flavin oxidoreductase frp family.


ensembl_gene_id: ETA_21910
symbol: ETA_21910
gene_biotype: protein_coding
description:
  Putative ABC transporter ATP-binding protein; silverDB:etchr02179; Belongs to the ABC transporter superfamily.


ensembl_gene_id: ETA_21930
symbol: moeA
gene_biotype: protein_coding
description:
  Molybdopterin biosynthesis; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.


ensembl_gene_id: ETA_21970
symbol: csbC
gene_biotype: protein_coding
description:
  Probable metabolite transport protein; silverDB:etchr02185; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.


ensembl_gene_id: ETA_22050
symbol: dps
gene_biotype: protein_coding
description:
  DNA protection during starvation protein; During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co-crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction.


ensembl_gene_id: ETA_22070
symbol: glnH
gene_biotype: protein_coding
description:
  Glutamine high-affinity transporter; silverDB:etchr02195; Belongs to the bacterial solute-binding protein 3 family.


ensembl_gene_id: ETA_22110
symbol: rlmF
gene_biotype: protein_coding
description:
  Conserved hypothetical protein (DUF890); Specifically methylates the adenine in position 1618 of 23S rRNA.


ensembl_gene_id: ETA_22120
symbol: ETA_22120
gene_biotype: protein_coding
description:
  Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family; silverDB:etchr02200.


ensembl_gene_id: ETA_22200
symbol: hutI
gene_biotype: protein_coding
description:
  Imidazolonepropionase; silverDB:etchr02208; Belongs to the metallo-dependent hydrolases superfamily. HutI family.


ensembl_gene_id: ETA_22390
symbol: idi
gene_biotype: protein_coding
description:
  Isopentenyl-diphosphate delta-isomerase; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).


ensembl_gene_id: ETA_22430
symbol: dld
gene_biotype: protein_coding
description:
  D-lactate dehydrogenase; Catalyzes the oxidation of D-lactate to pyruvate. Belongs to the quinone-dependent D-lactate dehydrogenase family.


ensembl_gene_id: ETA_22460
symbol: pbpG
gene_biotype: protein_coding
description:
  Penicillin-binding protein 7 (D-alanyl-D-alanine-endopeptidase); silverDB:etchr02234; Belongs to the peptidase S11 family.


ensembl_gene_id: ETA_22500
symbol: dusC
gene_biotype: protein_coding
description:
  Putative dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs. Belongs to the Dus family. DusC subfamily.


ensembl_gene_id: ETA_22510
symbol: rhlE
gene_biotype: protein_coding
description:
  Putative ATP-dependent RNA helicase; DEAD-box RNA helicase involved in ribosome assembly. Has RNA- dependent ATPase activity and unwinds double-stranded RNA.


ensembl_gene_id: ETA_22570
symbol: moaC
gene_biotype: protein_coding
description:
  Molybdopterin cofactor biosynthesis protein; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.


ensembl_gene_id: ETA_22580
symbol: moaB
gene_biotype: protein_coding
description:
  Molybdopterin biosynthesis; May be involved in the biosynthesis of molybdopterin. Belongs to the MoaB/Mog family.


ensembl_gene_id: ETA_22590
symbol: moaA
gene_biotype: protein_coding
description:
  Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.


ensembl_gene_id: ETA_22600
symbol: ybhK
gene_biotype: protein_coding
description:
  Conserved hypothetical protein YbhK; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family.


ensembl_gene_id: ETA_22610
symbol: uvrB
gene_biotype: protein_coding
description:
  UvrABC system protein B (Excinuclease ABC subunit B); The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the [...]


ensembl_gene_id: ETA_22630
symbol: bioD
gene_biotype: protein_coding
description:
  Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. Belongs to the dethiobiotin synthetase family.


ensembl_gene_id: ETA_22640
symbol: bioC
gene_biotype: protein_coding
description:
  Biotin synthesis protein; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.


ensembl_gene_id: ETA_22650
symbol: bioF
gene_biotype: protein_coding
description:
  7-keto-8-amino pelargonic acid synthetase (8-amino-7-oxononanoate synthase); Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.


ensembl_gene_id: ETA_22660
symbol: bioB
gene_biotype: protein_coding
description:
  Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.


ensembl_gene_id: ETA_22670
symbol: bioA
gene_biotype: protein_coding
description:
  Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.


ensembl_gene_id: ETA_22700
symbol: pgl
gene_biotype: protein_coding
description:
  6-phosphogluconolactonase; Catalyzes the hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate.


ensembl_gene_id: ETA_22720
symbol: modC
gene_biotype: protein_coding
description:
  Molybdenum import ATP-binding protein; Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Molybdate importer (TC 3.A.1.8) family.


ensembl_gene_id: ETA_22730
symbol: modB
gene_biotype: protein_coding
description:
  Molybdenum transport system permease protein; Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: ETA_22750
symbol: acrZ
gene_biotype: protein_coding
description:
  Putative outer membrane or exported; AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export.


ensembl_gene_id: ETA_22780
symbol: galT
gene_biotype: protein_coding
description:
  Galactose-1-phosphate uridylyltransferase; silverDB:etchr02266; Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.


ensembl_gene_id: ETA_22790
symbol: galK
gene_biotype: protein_coding
description:
  Galactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily.


ensembl_gene_id: ETA_22810
symbol: gpmA
gene_biotype: protein_coding
description:
  2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.


ensembl_gene_id: ETA_22840
symbol: aroG
gene_biotype: protein_coding
description:
  3-deoxy-D-arabinoheptulosonate-7-phosphate synthase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP).


ensembl_gene_id: ETA_22880
symbol: nadA
gene_biotype: protein_coding
description:
  Quinolinate synthetase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate; Belongs to the quinolinate synthase A family. Type 1 subfamily.


ensembl_gene_id: ETA_22890
symbol: ETA_22890
gene_biotype: protein_coding
description:
  Methylated-DNA-(Protein)-cysteine S-methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.


ensembl_gene_id: ETA_22910
symbol: cpoB
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family.


ensembl_gene_id: ETA_22920
symbol: pal
gene_biotype: protein_coding
description:
  Peptidoglycan-associated lipoprotein Pal, OmpA family of porins; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: ETA_22930
symbol: tolB
gene_biotype: protein_coding
description:
  Protein TolB (translocation of group A colicins); Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.


ensembl_gene_id: ETA_22950
symbol: tolR
gene_biotype: protein_coding
description:
  TolR colicin import membrane protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolQ, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.


ensembl_gene_id: ETA_22960
symbol: tolQ
gene_biotype: protein_coding
description:
  TolQ colicin import protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolR, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.


ensembl_gene_id: ETA_23010
symbol: sucD
gene_biotype: protein_coding
description:
  Succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.


ensembl_gene_id: ETA_23020
symbol: sucC
gene_biotype: protein_coding
description:
  Succinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.


ensembl_gene_id: ETA_23030
symbol: sucB
gene_biotype: protein_coding
description:
  Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).


ensembl_gene_id: ETA_23050
symbol: sdhB
gene_biotype: protein_coding
description:
  Succinate dehydrogenase, iron sulfur protein; silverDB:etchr02293; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.


ensembl_gene_id: ETA_23060
symbol: sdhA
gene_biotype: protein_coding
description:
  Succinate dehydrogenase flavoprotein subunit; silverDB:etchr02294; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.


ensembl_gene_id: ETA_23070
symbol: sdhD
gene_biotype: protein_coding
description:
  Succinate dehydrogenase hydrophobic membrane anchor protein; Membrane-anchoring subunit of succinate dehydrogenase (SDH).


ensembl_gene_id: ETA_23100
symbol: nei
gene_biotype: protein_coding
description:
  Endonuclease VIII; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine. Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.


ensembl_gene_id: ETA_23110
symbol: pcp
gene_biotype: protein_coding
description:
  Pyrrolidone-carboxylate peptidase; Removes 5-oxoproline from various penultimate amino acid residues except L-proline; Belongs to the peptidase C15 family.


ensembl_gene_id: ETA_23140
symbol: pxpA
gene_biotype: protein_coding
description:
  Uncharacterized proteins, homologs of lactam utilization protein B; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.


ensembl_gene_id: ETA_23220
symbol: seqA
gene_biotype: protein_coding
description:
  Negative modulator of initiation of replication; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated.


ensembl_gene_id: ETA_23250
symbol: fldA
gene_biotype: protein_coding
description:
  Flavodoxin 1; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family.


ensembl_gene_id: ETA_23310
symbol: nagB
gene_biotype: protein_coding
description:
  Glucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.


ensembl_gene_id: ETA_23370
symbol: miaB
gene_biotype: protein_coding
description:
  Putative tRNA-thiotransferase; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.


ensembl_gene_id: ETA_23390
symbol: ybeY
gene_biotype: protein_coding
description:
  Conserved hypothetical protein (UPF0054); Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.


ensembl_gene_id: ETA_23410
symbol: lnt
gene_biotype: protein_coding
description:
  Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily.


ensembl_gene_id: ETA_23470
symbol: leuS
gene_biotype: protein_coding
description:
  Leucyl-tRNA synthetase; silverDB:etchr02335; Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: ETA_23480
symbol: rlpB
gene_biotype: protein_coding
description:
  Rare lipoprotein B; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.


ensembl_gene_id: ETA_23500
symbol: nadD
gene_biotype: protein_coding
description:
  Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).


ensembl_gene_id: ETA_23510
symbol: ybeB
gene_biotype: protein_coding
description:
  Conserved hHypothetical protein YbeB; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.


ensembl_gene_id: ETA_23520
symbol: rlmH
gene_biotype: protein_coding
description:
  Conserved hypothetical protein (DUF163); Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family.


ensembl_gene_id: ETA_23530
symbol: mrdA
gene_biotype: protein_coding
description:
  Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.


ensembl_gene_id: ETA_23540
symbol: mrdB
gene_biotype: protein_coding
description:
  Strongly similar to rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.


ensembl_gene_id: ETA_23550
symbol: rlpA
gene_biotype: protein_coding
description:
  Rare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.


ensembl_gene_id: ETA_23580
symbol: lipB
gene_biotype: protein_coding
description:
  Lipoyltransferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.


ensembl_gene_id: ETA_23590
symbol: lipA
gene_biotype: protein_coding
description:
  Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.


ensembl_gene_id: ETA_23600
symbol: tatE
gene_biotype: protein_coding
description:
  Sec-independent protein translocase protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA; Belongs to the TatA/E family. TatE subfamily.


ensembl_gene_id: ETA_23630
symbol: pagP
gene_biotype: protein_coding
description:
  Antimicrobial peptide resistance and lipid A acylation protein; Transfers a palmitate residue from the sn-1 position of a phospholipid to the N-linked hydroxymyristate on the proximal unit of lipid A or its precursors.


ensembl_gene_id: ETA_23770
symbol: arnF
gene_biotype: protein_coding
description:
  Putative transport/receptor protein; Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane; Belongs to the ArnF family.


ensembl_gene_id: ETA_23780
symbol: yfbW
gene_biotype: protein_coding
description:
  Putative inner membrane protein; Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane; Belongs to the ArnE family.


ensembl_gene_id: ETA_23790
symbol: arnT
gene_biotype: protein_coding
description:
  Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase; Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides. Belongs to the glycosyltransferase 83 family.


ensembl_gene_id: ETA_23800
symbol: arnD
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; Belongs to the polysaccharide deacetylase family. ArnD deformylase subfamily.


ensembl_gene_id: ETA_23810
symbol: arnA
gene_biotype: protein_coding
description:
  UDP-glucuronic acid oxidase, UDP-4-keto-hexauronic acid decarboxylating; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; In the C-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarbox [...]


ensembl_gene_id: ETA_23820
symbol: arnC
gene_biotype: protein_coding
description:
  Undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase; Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.


ensembl_gene_id: ETA_23830
symbol: arnB
gene_biotype: protein_coding
description:
  UDP-4-amino-4-deoxy-L-arabinose-oxoglutarate aminotransferase; Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; Belongs to the DegT/DnrJ/EryC1 family. ArnB subfamily.


ensembl_gene_id: ETA_23880
symbol: ETA_23880
gene_biotype: protein_coding
description:
  Putative ATP-binding component of ABC transporter; silverDB:etchr02376; Belongs to the ABC transporter superfamily.


ensembl_gene_id: ETA_23910
symbol: ophA
gene_biotype: protein_coding
description:
  ABC-type dipeptide transport system, periplasmic component (OphA), DdpA region; silverDB:etchr02379.


ensembl_gene_id: ETA_24020
symbol: lysR
gene_biotype: protein_coding
description:
  Transcriptional regulator; silverDB:etchr02390; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: ETA_24050
symbol: ETA_24050
gene_biotype: protein_coding
description:
  Acetyl-CoA acetyltransferase; silverDB:etchr02393; Belongs to the thiolase-like superfamily. Thiolase family.


ensembl_gene_id: ETA_24090
symbol: ETA_24090
gene_biotype: protein_coding
description:
  4-oxalocrotonate tautomerase family protein; silverDB:etchr02397; Belongs to the 4-oxalocrotonate tautomerase family.


ensembl_gene_id: ETA_24130
symbol: ETA_24130
gene_biotype: protein_coding
description:
  Regulatory protein LysR family (substrate-binding); silverDB:etchr02401; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: ETA_24340
symbol: folD
gene_biotype: protein_coding
description:
  Bifunctional protein [includes: methylenetetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.


ensembl_gene_id: ETA_24380
symbol: cysS
gene_biotype: protein_coding
description:
  Cysteinyl-tRNA synthetase; silverDB:etchr02426; Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: ETA_24400
symbol: ppiB
gene_biotype: protein_coding
description:
  Peptidyl-prolyl cis-trans isomerase B (Rotamase B); PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.


ensembl_gene_id: ETA_24410
symbol: lpxH
gene_biotype: protein_coding
description:
  UDP-2,3-diacylglucosamine hydrolase; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: ETA_24420
symbol: purE
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazole carboxylase catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).


ensembl_gene_id: ETA_24430
symbol: purK
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazole carboxylase ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).


ensembl_gene_id: ETA_24500
symbol: ETA_24500
gene_biotype: protein_coding
description:
  Putative cytoplasmic protein, fragment; silverDB:etchr02437; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: ETA_24570
symbol: ETA_24570
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; silverDB:etchr02445; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.


ensembl_gene_id: ETA_24580
symbol: ETA_24580
gene_biotype: protein_coding
description:
  LysR-family transcriptional regulator; silverDB:etchr02446; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: ETA_24600
symbol: ushA
gene_biotype: protein_coding
description:
  UshA protein (UDP-sugar hydrolase and 5'-nucleotidase) (EC 3.6.1.45; silverDB:etchr02448; Belongs to the 5'-nucleotidase family.


ensembl_gene_id: ETA_24620
symbol: ETA_24620
gene_biotype: protein_coding
description:
  Potassium antiporter; silverDB:etchr02450; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.


ensembl_gene_id: ETA_24640
symbol: hemH
gene_biotype: protein_coding
description:
  Ferrochelatase (Protoheme ferro-lyase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.


ensembl_gene_id: ETA_24650
symbol: adk
gene_biotype: protein_coding
description:
  Adenylate kinase (ATP-AMP transphosphorylase); Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.


ensembl_gene_id: ETA_24700
symbol: ETA_24700
gene_biotype: protein_coding
description:
  LysR-family transcriptional regulator; silverDB:etchr02458; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: ETA_24720
symbol: recR
gene_biotype: protein_coding
description:
  Recombination protein; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.


ensembl_gene_id: ETA_24730
symbol: ETA_24730
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.


ensembl_gene_id: ETA_24740
symbol: dnaX
gene_biotype: protein_coding
description:
  DNA polymerase III subunit tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.


ensembl_gene_id: ETA_24750
symbol: apt
gene_biotype: protein_coding
description:
  Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.


ensembl_gene_id: ETA_24800
symbol: acrA
gene_biotype: protein_coding
description:
  Acriflavine resistance protein A precursor; silverDB:etchr02468; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: ETA_24830
symbol: rpmJ
gene_biotype: protein_coding
description:
  50S ribosomal protein L36; silverDB:etchr02471; Belongs to the bacterial ribosomal protein bL36 family.


ensembl_gene_id: ETA_24840
symbol: ETA_24840
gene_biotype: protein_coding
description:
  ABC transporter substrate-binding protein; silverDB:etchr02472; Belongs to the bacterial solute-binding protein 9 family.


ensembl_gene_id: ETA_25000
symbol: queC
gene_biotype: protein_coding
description:
  Queuosine biosynthesis protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.


ensembl_gene_id: ETA_25040
symbol: hopD
gene_biotype: protein_coding
description:
  HopD, DNA-binding protein HU-beta (synonym HupB); Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.


ensembl_gene_id: ETA_25050
symbol: lon
gene_biotype: protein_coding
description:
  ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.


ensembl_gene_id: ETA_25060
symbol: clpX1
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.


ensembl_gene_id: ETA_25070
symbol: clpP1
gene_biotype: protein_coding
description:
  Putative ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.


ensembl_gene_id: ETA_25080
symbol: clpX2
gene_biotype: protein_coding
description:
  ATP-dependent specificity component of ClpP serine protease, chaperone; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.


ensembl_gene_id: ETA_25110
symbol: tig
gene_biotype: protein_coding
description:
  Trigger factor (TF); Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.


ensembl_gene_id: ETA_25120
symbol: bolA
gene_biotype: protein_coding
description:
  Morphogene, putative regulator of murein genes; silverDB:etchr02500; Belongs to the BolA/IbaG family.


ensembl_gene_id: ETA_25160
symbol: cyoB
gene_biotype: protein_coding
description:
  Cytochrome o ubiquinol oxidase subunit I; silverDB:etchr02504; Belongs to the heme-copper respiratory oxidase family.


ensembl_gene_id: ETA_25190
symbol: cyoE
gene_biotype: protein_coding
description:
  Cytochrome o ubiquinol oxidase C subunit; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.


ensembl_gene_id: ETA_25220
symbol: panE
gene_biotype: protein_coding
description:
  2-dehydropantoate 2-reductase (KPA reductase); Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.


ensembl_gene_id: ETA_25240
symbol: thiI
gene_biotype: protein_coding
description:
  Thiamine biosynthesis protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.


ensembl_gene_id: ETA_25250
symbol: xseB
gene_biotype: protein_coding
description:
  Probable exodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.


ensembl_gene_id: ETA_25270
symbol: dxs
gene_biotype: protein_coding
description:
  1-deoxy-D-xylulose 5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.


ensembl_gene_id: ETA_25280
symbol: pgpA
gene_biotype: protein_coding
description:
  Phosphatidylglycerophosphatase A; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).


ensembl_gene_id: ETA_25290
symbol: thiL
gene_biotype: protein_coding
description:
  Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.


ensembl_gene_id: ETA_25300
symbol: nusB
gene_biotype: protein_coding
description:
  N utilization substance protein B; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.


ensembl_gene_id: ETA_25310
symbol: ribH
gene_biotype: protein_coding
description:
  6,7-dimethyl-8-ribityllumazine synthase (Riboflavin synthase); Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family.


ensembl_gene_id: ETA_25320
symbol: ribD
gene_biotype: protein_coding
description:
  Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.


ensembl_gene_id: ETA_25330
symbol: nrdR
gene_biotype: protein_coding
description:
  Transcriptional repressor NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.


ensembl_gene_id: ETA_25360
symbol: secF
gene_biotype: protein_coding
description:
  Protein-export membrane protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.


ensembl_gene_id: ETA_25380
symbol: yajC
gene_biotype: protein_coding
description:
  Conserved hypothetical protein YajC; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.


ensembl_gene_id: ETA_25390
symbol: tgt
gene_biotype: protein_coding
description:
  Queuine tRNA-ribosyltransferase (tRNA-guanine transglycosylase); Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on  [...]


ensembl_gene_id: ETA_25400
symbol: queA
gene_biotype: protein_coding
description:
  S-adenosylmethionine:tRNA ribosyltransferase-isomerase (Queuosine biosynthesis protein QueA); Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).


ensembl_gene_id: ETA_25440
symbol: brnQ
gene_biotype: protein_coding
description:
  Branched-chain amino acid transport system II carrier protein; Component of the transport system for branched-chain amino acids.


ensembl_gene_id: ETA_25490
symbol: sbcD
gene_biotype: protein_coding
description:
  Exonuclease subunit D; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.


ensembl_gene_id: ETA_25560
symbol: ppnP
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.


ensembl_gene_id: ETA_25630
symbol: aroL
gene_biotype: protein_coding
description:
  Shikimate kinase 2 (SK 2); Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.


ensembl_gene_id: ETA_25660
symbol: proC
gene_biotype: protein_coding
description:
  Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.


ensembl_gene_id: ETA_25880
symbol: crcB
gene_biotype: protein_coding
description:
  Camphor resistance CrcB protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.


ensembl_gene_id: ETA_25930
symbol: proA
gene_biotype: protein_coding
description:
  Gamma-glutamyl phosphate reductase (Glutamate-5-semialdehyde dehydrogenase); Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.


ensembl_gene_id: ETA_25940
symbol: proB
gene_biotype: protein_coding
description:
  Glutamate 5-kinase (Gamma-glutamyl kinase); Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.


ensembl_gene_id: ETA_25960
symbol: crl
gene_biotype: protein_coding
description:
  Curlin genes transcriptional activatory protein; Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32; Belongs to the Crl family.


ensembl_gene_id: ETA_25980
symbol: gpt
gene_biotype: protein_coding
description:
  Xanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.


ensembl_gene_id: ETA_26000
symbol: dinP
gene_biotype: protein_coding
description:
  Damage inducible protein P (DNA polymerase IV); Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.


ensembl_gene_id: ETA_26030
symbol: gmhA
gene_biotype: protein_coding
description:
  Phosphoheptose isomerase (Sedoheptulose 7-phosphate isomerase); Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.


ensembl_gene_id: ETA_26050
symbol: mtrK
gene_biotype: protein_coding
description:
  5-methylthioribose kinase; Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate.


ensembl_gene_id: ETA_26060
symbol: eif
gene_biotype: protein_coding
description:
  Putative translation initiation factor EIF-2B; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).


ensembl_gene_id: ETA_26070
symbol: mtnD
gene_biotype: protein_coding
description:
  Strongly similar to methionine salvage pathway enzyme E-2/E-2; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.


ensembl_gene_id: ETA_26080
symbol: masA
gene_biotype: protein_coding
description:
  Enolase-phosphatase; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.


ensembl_gene_id: ETA_26090
symbol: mtnB
gene_biotype: protein_coding
description:
  Probable aldolase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Belongs to the aldolase class II family. MtnB subfamily.


ensembl_gene_id: ETA_26140
symbol: ETA_26140
gene_biotype: protein_coding
description:
  Transthyretin family protein; silverDB:etchr02602; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.


ensembl_gene_id: ETA_26340
symbol: dnaQ
gene_biotype: protein_coding
description:
  DNA polymerase III epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.


ensembl_gene_id: ETA_26350
symbol: rnhA
gene_biotype: protein_coding
description:
  Putative ribonuclease H (RNase H); Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.


ensembl_gene_id: ETA_26370
symbol: gloB
gene_biotype: protein_coding
description:
  Putative hydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.


ensembl_gene_id: ETA_26420
symbol: clpB
gene_biotype: protein_coding
description:
  Chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.


ensembl_gene_id: ETA_26430
symbol: ETA_26430
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; silverDB:etchr02631; Belongs to the multicopper oxidase YfiH/RL5 family.


ensembl_gene_id: ETA_26440
symbol: rluD
gene_biotype: protein_coding
description:
  Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.


ensembl_gene_id: ETA_26450
symbol: bamD
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamA, the core component of the assembly machinery.


ensembl_gene_id: ETA_26490
symbol: aroF
gene_biotype: protein_coding
description:
  Phospho-2-dehydro-3-deoxyheptonate aldolase, Tyr-sensitive; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP).


ensembl_gene_id: ETA_26540
symbol: rplS
gene_biotype: protein_coding
description:
  50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.


ensembl_gene_id: ETA_26550
symbol: trmD
gene_biotype: protein_coding
description:
  tRNA (guanine-N(1)-)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.


ensembl_gene_id: ETA_26560
symbol: rimM
gene_biotype: protein_coding
description:
  16S rRNA-processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family.


ensembl_gene_id: ETA_26570
symbol: rpsP
gene_biotype: protein_coding
description:
  30S ribosomal protein S16; silverDB:etchr02645; Belongs to the bacterial ribosomal protein bS16 family.


ensembl_gene_id: ETA_26580
symbol: ffh
gene_biotype: protein_coding
description:
  Signal recognition particle protein (Fifty-four homolog); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into th [...]


ensembl_gene_id: ETA_26610
symbol: luxS
gene_biotype: protein_coding
description:
  Autoinducer-2 production protein; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.


ensembl_gene_id: ETA_26620
symbol: gshA
gene_biotype: protein_coding
description:
  Glutamate-cysteine ligase; silverDB:etchr02650; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.


ensembl_gene_id: ETA_26650
symbol: csrA
gene_biotype: protein_coding
description:
  Carbon storage regulator; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).


ensembl_gene_id: ETA_26660
symbol: alaS
gene_biotype: protein_coding
description:
  Alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain; Belongs to the class-II aminoacyl-tRNA synthetase family.


ensembl_gene_id: ETA_26680
symbol: recA
gene_biotype: protein_coding
description:
  Recombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.


ensembl_gene_id: ETA_26850
symbol: spaR2
gene_biotype: protein_coding
description:
  Surface presentation of antigens protein (Spa29 protein), Type III secretion apparatus; silverDB:etchr02673.


ensembl_gene_id: ETA_26940
symbol: mutS
gene_biotype: protein_coding
description:
  Phage integrase, fragment; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.


ensembl_gene_id: ETA_26950
symbol: rpoS
gene_biotype: protein_coding
description:
  RNA polymerase sigma factor RpoS; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.


ensembl_gene_id: ETA_26970
symbol: pcm
gene_biotype: protein_coding
description:
  Protein-L-isoaspartate O-methyltransferase; Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.


ensembl_gene_id: ETA_26980
symbol: surE
gene_biotype: protein_coding
description:
  5'/3'-nucleotidase SurE; Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP. Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20-25). Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs.


ensembl_gene_id: ETA_26990
symbol: truD
gene_biotype: protein_coding
description:
  tRNA pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family.


ensembl_gene_id: ETA_27000
symbol: ispF
gene_biotype: protein_coding
description:
  2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).


ensembl_gene_id: ETA_27010
symbol: ispD
gene_biotype: protein_coding
description:
  2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.


ensembl_gene_id: ETA_27020
symbol: ftsB
gene_biotype: protein_coding
description:
  Cell division protein ftsB homolog; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.


ensembl_gene_id: ETA_27050
symbol: cysN
gene_biotype: protein_coding
description:
  Sulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.


ensembl_gene_id: ETA_27070
symbol: cysG
gene_biotype: protein_coding
description:
  uroporphyrin-III C-methylase, siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family.  In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.


ensembl_gene_id: ETA_27090
symbol: cysH
gene_biotype: protein_coding
description:
  Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.


ensembl_gene_id: ETA_27100
symbol: cysI
gene_biotype: protein_coding
description:
  Sulfite reductase [NADPH] hemoprotein beta-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.


ensembl_gene_id: ETA_27110
symbol: cysJ
gene_biotype: protein_coding
description:
  Sulfite reductase [NADPH] flavoprotein alpha-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component. Belongs to the NADPH-dependent sulphite reductase flavoprotein subunit CysJ family. In the N-terminal section; belongs to the flavodoxin family.


ensembl_gene_id: ETA_27150
symbol: ETA_27150
gene_biotype: protein_coding
description:
  Putative amino-acid ABC transporter, periplasmic amino acid-binding protein; silverDB:etchr02703; Belongs to the bacterial solute-binding protein 3 family.


ensembl_gene_id: ETA_27160
symbol: ETA_27160
gene_biotype: protein_coding
description:
  LysR-family transcriptional regulator; silverDB:etchr02704; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: ETA_27180
symbol: queE
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.


ensembl_gene_id: ETA_27200
symbol: eno
gene_biotype: protein_coding
description:
  Enolase (2-phospho-D-glycerate hydrolyase); Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.


ensembl_gene_id: ETA_27210
symbol: pyrG
gene_biotype: protein_coding
description:
  CTP synthase (UTP-ammonia ligase); Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.


ensembl_gene_id: ETA_27230
symbol: relA
gene_biotype: protein_coding
description:
  GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.


ensembl_gene_id: ETA_27240
symbol: rumA
gene_biotype: protein_coding
description:
  23S rRNA (uracil-5-)-methyltransferase; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.


ensembl_gene_id: ETA_27300
symbol: syd
gene_biotype: protein_coding
description:
  Protein syd; Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function. Belongs to the Syd family.


ensembl_gene_id: ETA_27310
symbol: queF
gene_biotype: protein_coding
description:
  NADPH-dependent 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).


ensembl_gene_id: ETA_27330
symbol: xni
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease IX; Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.


ensembl_gene_id: ETA_27340
symbol: mtfA
gene_biotype: protein_coding
description:
  Putative RNA 2'-O-ribose methyltransferase; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.


ensembl_gene_id: ETA_27360
symbol: gcvA
gene_biotype: protein_coding
description:
  Glycine cleavage system transcriptional activator; silverDB:etchr02724; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: ETA_27410
symbol: mltA
gene_biotype: protein_coding
description:
  Membrane-bound lytic murein transglycosylase A; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division.


ensembl_gene_id: ETA_27430
symbol: argA
gene_biotype: protein_coding
description:
  Amino-acid acetyltransferase; silverDB:etchr02731; Belongs to the acetyltransferase family. ArgA subfamily.


ensembl_gene_id: ETA_27450
symbol: recD
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease V alpha chain; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repa [...]


ensembl_gene_id: ETA_27460
symbol: recB
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease V beta chain; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repai [...]


ensembl_gene_id: ETA_27490
symbol: ETA_27490
gene_biotype: protein_coding
description:
  Cysteine synthase A; silverDB:etchr02737; Belongs to the cysteine synthase/cystathionine beta- synthase family.


ensembl_gene_id: ETA_27530
symbol: recC
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease V gamma chain; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repa [...]


ensembl_gene_id: ETA_27590
symbol: thyA
gene_biotype: protein_coding
description:
  Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.


ensembl_gene_id: ETA_27600
symbol: lgt
gene_biotype: protein_coding
description:
  Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.


ensembl_gene_id: ETA_27610
symbol: ptsP
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate-protein phosphotransferase; silverDB:etchr02749; Belongs to the PEP-utilizing enzyme family.


ensembl_gene_id: ETA_27620
symbol: nudH
gene_biotype: protein_coding
description:
  Putative (di)nucleoside polyphosphate hydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily.


ensembl_gene_id: ETA_27630
symbol: mutH
gene_biotype: protein_coding
description:
  DNA mismatch repair protein; Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair. Belongs to the MutH family.


ensembl_gene_id: ETA_27680
symbol: aas
gene_biotype: protein_coding
description:
  AAS bifunctional protein; Plays a role in lysophospholipid acylation. Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1.


ensembl_gene_id: ETA_27720
symbol: acrF
gene_biotype: protein_coding
description:
  Multidrug resistance protein; silverDB:etchr02760; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: ETA_27730
symbol: acrE
gene_biotype: protein_coding
description:
  Multidrug resistance protein; silverDB:etchr02761; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: ETA_27740
symbol: ETA_27740
gene_biotype: protein_coding
description:
  Secretion protein HlyD; silverDB:etchr02762; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: ETA_27760
symbol: ETA_27760
gene_biotype: protein_coding
description:
  Biotin sulfoxide reductase; silverDB:etchr02764; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: ETA_27780
symbol: lysA
gene_biotype: protein_coding
description:
  Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.


ensembl_gene_id: ETA_27790
symbol: lysR-2
gene_biotype: protein_coding
description:
  Transcriptional activator protein LysR; silverDB:etchr02767; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: ETA_27820
symbol: lysS
gene_biotype: protein_coding
description:
  Lysyl tRNA synthetase; silverDB:etchr02770; Belongs to the class-II aminoacyl-tRNA synthetase family.


ensembl_gene_id: ETA_27830
symbol: prfB
gene_biotype: protein_coding
description:
  Putative peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.


ensembl_gene_id: ETA_27860
symbol: dsbC
gene_biotype: protein_coding
description:
  Protein disulfide isomerase II; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily.


ensembl_gene_id: ETA_27870
symbol: xerD
gene_biotype: protein_coding
description:
  Tyrosine recombinase XerD; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerC binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerD specifically exchanges t [...]


ensembl_gene_id: ETA_27920
symbol: ETA_27920
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication; Belongs to the tRNA-modifying YgfZ family.


ensembl_gene_id: ETA_27960
symbol: gcvP
gene_biotype: protein_coding
description:
  Glycine dehydrogenase [decarboxylating]; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.


ensembl_gene_id: ETA_27970
symbol: gcvH
gene_biotype: protein_coding
description:
  Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.


ensembl_gene_id: ETA_27980
symbol: gcvT
gene_biotype: protein_coding
description:
  Aminomethyltransferase (Glycine cleavage system T protein); The glycine cleavage system catalyzes the degradation of glycine.


ensembl_gene_id: ETA_28050
symbol: zapA
gene_biotype: protein_coding
description:
  Conserved hypothetical protein (DUF710); Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.


ensembl_gene_id: ETA_28060
symbol: ETA_28060
gene_biotype: protein_coding
description:
  Putative 5-formyltetrahydrofolate cyclo-ligase; silverDB:etchr02794; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.


ensembl_gene_id: ETA_28070
symbol: serA
gene_biotype: protein_coding
description:
  D-3-phosphoglycerate dehydrogenase; silverDB:etchr02795; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: ETA_28080
symbol: rpiA
gene_biotype: protein_coding
description:
  Ribose-5-phosphate isomerase A 1 (Phosphoriboisomerase A 1); Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.


ensembl_gene_id: ETA_28090
symbol: iciA
gene_biotype: protein_coding
description:
  Chromosome initiation inhibitor (OriC replication inhibitor); Controls the transcription of genes involved in arginine and lysine metabolism; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: ETA_28110
symbol: argO
gene_biotype: protein_coding
description:
  Arginine exporter protein ArgO; Involved in the export of arginine. Important to control the intracellular level of arginine and the correct balance between arginine and lysine; Belongs to the LysE/ArgO transporter (TC 2.A.75) family.


ensembl_gene_id: ETA_28130
symbol: fba
gene_biotype: protein_coding
description:
  Fructose-bisphosphate aldolase class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.


ensembl_gene_id: ETA_28150
symbol: epd
gene_biotype: protein_coding
description:
  D-erythrose 4-phosphate dehydrogenase; Catalyzes the NAD-dependent conversion of D-erythrose 4- phosphate to 4-phosphoerythronate.


ensembl_gene_id: ETA_28160
symbol: tktA
gene_biotype: protein_coding
description:
  Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.


ensembl_gene_id: ETA_28230
symbol: speB
gene_biotype: protein_coding
description:
  Agmatinase (Agmatine ureohydrolase); Catalyzes the formation of putrescine from agmatine. Belongs to the arginase family. Agmatinase subfamily.


ensembl_gene_id: ETA_28260
symbol: metK
gene_biotype: protein_coding
description:
  S-adenosylmethionine synthetase (Methionine adenosyltransferase); Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.


ensembl_gene_id: ETA_28270
symbol: galP
gene_biotype: protein_coding
description:
  Galactose-proton symport (Galactose transporter); silverDB:etchr02815; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.


ensembl_gene_id: ETA_28300
symbol: yggJ
gene_biotype: protein_coding
description:
  Conserved hypothetical protein YggJ; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.


ensembl_gene_id: ETA_28310
symbol: rimK
gene_biotype: protein_coding
description:
  Glutathione synthase/Ribosomal protein S6 modification enzyme(glutaminyl transferase); silverDB:etchr02819; Belongs to the prokaryotic GSH synthase family.


ensembl_gene_id: ETA_28330
symbol: yqgF
gene_biotype: protein_coding
description:
  Putative Holliday junction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family.


ensembl_gene_id: ETA_28360
symbol: ETA_28360
gene_biotype: protein_coding
description:
  Probable RNA polymerase ECF-type sigma factor; silverDB:etchr02824; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: ETA_28390
symbol: yggS
gene_biotype: protein_coding
description:
  Conserved hypothetical protein YggS; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.


ensembl_gene_id: ETA_28410
symbol: ETA_28410
gene_biotype: protein_coding
description:
  HAM1 protein homolog; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.


ensembl_gene_id: ETA_28420
symbol: ETA_28420
gene_biotype: protein_coding
description:
  Putative oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.


ensembl_gene_id: ETA_28450
symbol: trmB
gene_biotype: protein_coding
description:
  tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.


ensembl_gene_id: ETA_28470
symbol: ETA_28470
gene_biotype: protein_coding
description:
  Probable Fe(2+)-trafficking protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes; Belongs to the Fe(2+)-trafficking protein family.


ensembl_gene_id: ETA_28480
symbol: mltC
gene_biotype: protein_coding
description:
  Membrane-bound lytic murein transglycosylase C (Murein hydrolase C); Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division.


ensembl_gene_id: ETA_28540
symbol: mrkC
gene_biotype: protein_coding
description:
  Putative outer membrane fimbrial usher porin (involved in the expression of type III fimbriae) MrkC; silverDB:etchr02842.


ensembl_gene_id: ETA_28850
symbol: pqqF
gene_biotype: protein_coding
description:
  Coenzyme PQQ synthesis protein F (Pyrroloquinoline quinone biosynthesis protein F); silverDB:etchr02873; Belongs to the peptidase M16 family.


ensembl_gene_id: ETA_28860
symbol: pqqE
gene_biotype: protein_coding
description:
  Coenzyme PQQ synthesis protein E (Pyrroloquinoline quinone biosynthesis protein E); Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).


ensembl_gene_id: ETA_28870
symbol: pqqD
gene_biotype: protein_coding
description:
  Coenzyme PQQ synthesis protein D (Pyrroloquinoline quinone biosynthesis protein D); Functions as a PqqA binding protein and presents PqqA to PqqE, in the pyrroloquinoline quinone (PQQ) biosynthetic pathway.


ensembl_gene_id: ETA_28880
symbol: pqqC
gene_biotype: protein_coding
description:
  Coenzyme PQQ synthesis protein C (Pyrroloquinoline quinone biosynthesis protein C); Ring cyclization and eight-electron oxidation of 3a-(2-amino- 2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9- dicarboxylic-acid to PQQ.


ensembl_gene_id: ETA_28890
symbol: pqqB
gene_biotype: protein_coding
description:
  Coenzyme PQQ synthesis protein B (Pyrroloquinoline quinone biosynthesis protein B); May be involved in the transport of PQQ or its precursor to the periplasm; Belongs to the PqqB family.


ensembl_gene_id: ETA_28900
symbol: pqqA
gene_biotype: protein_coding
description:
  Coenzyme PQQ biosynthesis protein A; Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis. PQQ is probably formed by cross-linking a specific glutamate to a specific tyrosine residue and excising these residues from the peptide; Belongs to the PqqA family.


ensembl_gene_id: ETA_28940
symbol: idnO
gene_biotype: protein_coding
description:
  Gluconate 5-dehydrogenase; silverDB:etchr02881; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: ETA_28960
symbol: rsmD
gene_biotype: protein_coding
description:
  Putative ribosomal RNA small subunit methyltransferase D; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.


ensembl_gene_id: ETA_29010
symbol: ETA_29010
gene_biotype: protein_coding
description:
  Putative 4-aminobutyrate aminotransferase; silverDB:etchr02888; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: ETA_29050
symbol: ygjU
gene_biotype: protein_coding
description:
  Inner membrane symporter YgjU; Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system). Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: ETA_29070
symbol: yqjB
gene_biotype: protein_coding
description:
  Putative outer membrane protein, YqjB; Modulates the activity of the EnvZ/OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR.


ensembl_gene_id: ETA_29140
symbol: ETA_29140
gene_biotype: protein_coding
description:
  LysR-type transcriptional regulator; silverDB:etchr02901; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: ETA_29170
symbol: bacA
gene_biotype: protein_coding
description:
  Similar to bacitracin synthetase 1 (BA1), protein contains non-ribosomal peptide synthetase modules; silverDB:etchr02904.


ensembl_gene_id: ETA_29180
symbol: pspT
gene_biotype: protein_coding
description:
  Probable 4'-phosphopantetheinyl transferase; silverDB:etchr02905; Belongs to the P-Pant transferase superfamily.


ensembl_gene_id: ETA_29190
symbol: rsmI
gene_biotype: protein_coding
description:
  Putative tetrapyrrole methylase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.


ensembl_gene_id: ETA_29200
symbol: lpoA
gene_biotype: protein_coding
description:
  Putative lipoprotein; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a).


ensembl_gene_id: ETA_29220
symbol: diaA
gene_biotype: protein_coding
description:
  DnaA initiator-associating protein DiaA; Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein. Belongs to the SIS family. DiaA subfamily.


ensembl_gene_id: ETA_29340
symbol: pmbA
gene_biotype: protein_coding
description:
  PmbA protease involved in Microcin B17 maturation and sensitivity to the DNA gyrase inhibitor LetD; silverDB:etchr02921.


ensembl_gene_id: ETA_29360
symbol: mpl
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily.


ensembl_gene_id: ETA_29390
symbol: ppa
gene_biotype: protein_coding
description:
  Inorganic pyrophosphatase (Pyrophosphate phospho-hydrolase); Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.


ensembl_gene_id: ETA_29460
symbol: cysQ
gene_biotype: protein_coding
description:
  Protein CysQ, probable regulator; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family.


ensembl_gene_id: ETA_29470
symbol: cpdB
gene_biotype: protein_coding
description:
  2',3'-cyclic-nucleotide 2'-phosphodiesterase; silverDB:etchr02934; Belongs to the 5'-nucleotidase family.


ensembl_gene_id: ETA_29530
symbol: rpsR
gene_biotype: protein_coding
description:
  30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.


ensembl_gene_id: ETA_29540
symbol: priB
gene_biotype: protein_coding
description:
  Primosomal replication protein n; Binds single-stranded DNA at the primosome assembly site (PAS); Belongs to the PriB family.


ensembl_gene_id: ETA_29590
symbol: rlmB
gene_biotype: protein_coding
description:
  23S rRNA (guanosine-2'-O-)-methyltransferase; Specifically methylates the ribose of guanosine 2251 in 23S rRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.


ensembl_gene_id: ETA_29600
symbol: rnr
gene_biotype: protein_coding
description:
  Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. Belongs to the RNR ribonuclease family. RNase R subfamily.


ensembl_gene_id: ETA_29620
symbol: purA
gene_biotype: protein_coding
description:
  Adenylosuccinate synthetase (IMP-aspartate ligase); Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.


ensembl_gene_id: ETA_29650
symbol: hflK
gene_biotype: protein_coding
description:
  Protease specific for phage lambda cII repressor; HflC and HflK could encode or regulate a protease.


ensembl_gene_id: ETA_29660
symbol: hflX
gene_biotype: protein_coding
description:
  GTP-binding protein HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.


ensembl_gene_id: ETA_29670
symbol: hfQ
gene_biotype: protein_coding
description:
  Host factor-I protein; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.


ensembl_gene_id: ETA_29680
symbol: miaA
gene_biotype: protein_coding
description:
  tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.


ensembl_gene_id: ETA_29690
symbol: mutL
gene_biotype: protein_coding
description:
  DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.


ensembl_gene_id: ETA_29720
symbol: yjeF
gene_biotype: protein_coding
description:
  Putative sugar kinase, YjeF; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.  Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of b [...]


ensembl_gene_id: ETA_29730
symbol: orn
gene_biotype: protein_coding
description:
  Oligoribonuclease; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family.


ensembl_gene_id: ETA_29740
symbol: engC
gene_biotype: protein_coding
description:
  Probable GTPase EngC; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.


ensembl_gene_id: ETA_29750
symbol: psd
gene_biotype: protein_coding
description:
  Phosphatidylserine decarboxylase proenzyme; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).


ensembl_gene_id: ETA_29770
symbol: poxA
gene_biotype: protein_coding
description:
  Putative lysyl-tRNA synthetase (Lysine-tRNA ligase); With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF- P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta-lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P; Belongs to the class-II aminoacyl-tRNA synthetase family. EpmA subfamily.


ensembl_gene_id: ETA_29780
symbol: blc
gene_biotype: protein_coding
description:
  Outer membrane lipoprotein; Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.


ensembl_gene_id: ETA_29800
symbol: efp
gene_biotype: protein_coding
description:
  Elongation factor P (EF-P); Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation; Belongs to the elongation factor P family.


ensembl_gene_id: ETA_29830
symbol: groL
gene_biotype: protein_coding
description:
  60 kDa chaperonin (Protein Cpn60); Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.


ensembl_gene_id: ETA_29840
symbol: groS
gene_biotype: protein_coding
description:
  10 kDa chaperonin (Protein Cpn10); Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.


ensembl_gene_id: ETA_29870
symbol: dcuA
gene_biotype: protein_coding
description:
  Anaerobic C4-dicarboxylate transporter; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane; Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.


ensembl_gene_id: ETA_29880
symbol: dsbD
gene_biotype: protein_coding
description:
  Thiol:disulfide interchange protein DsbD; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily.


ensembl_gene_id: ETA_30080
symbol: ETA_30080
gene_biotype: protein_coding
description:
  3-oxoacyl-[acyl-carrier-protein] synthase II; silverDB:etchr02995; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: ETA_30100
symbol: macB
gene_biotype: protein_coding
description:
  Macrolide-specific ABC-type efflux carrier; silverDB:etchr02997; Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family.


ensembl_gene_id: ETA_30110
symbol: macA
gene_biotype: protein_coding
description:
  Macrolide-specific efflux protein; silverDB:etchr02998; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: ETA_30260
symbol: ETA_30260
gene_biotype: protein_coding
description:
  Hypothetical protein similar to P-47 (involved in botulinum toxin synthesis) protein; silverDB:etchr03013.


ensembl_gene_id: ETA_30330
symbol: fecI
gene_biotype: protein_coding
description:
  RNA polymerase sigma factor FecI; silverDB:etchr03020; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: ETA_30370
symbol: fecC
gene_biotype: protein_coding
description:
  Iron(III) dicitrate transport system permease protein FecC; silverDB:etchr03024; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: ETA_30380
symbol: fecD
gene_biotype: protein_coding
description:
  Iron(III) dicitrate transport system permease protein FecD; silverDB:etchr03025; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: ETA_30480
symbol: treF
gene_biotype: protein_coding
description:
  Cytoplasmic trehalase (Alpha,alpha-trehalose glucohydrolase); Hydrolyzes trehalose to glucose. Could be involved, in cells returning to low osmolarity conditions, in the utilization of the accumulated cytoplasmic trehalose, which was synthesized in response to high osmolarity.


ensembl_gene_id: ETA_30530
symbol: ETA_30530
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; silverDB:etchr03040; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: ETA_30560
symbol: ETA_30560
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; silverDB:etchr03043; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: ETA_30670
symbol: gltP
gene_biotype: protein_coding
description:
  Proton glutamate symport protein; Catalyzes the proton-dependent transport of glutamate and aspartate; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. GltP subfamily.


ensembl_gene_id: ETA_30680
symbol: acs
gene_biotype: protein_coding
description:
  Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. Enables the cell to use acetate during aerobic growth to generate energy via the TCA cycle, and biosynthetic compounds via the glyoxylate shunt. A [...]


ensembl_gene_id: ETA_30700
symbol: actP
gene_biotype: protein_coding
description:
  Cation/acetate symporter actP (Acetate transporter actP); Transports acetate; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: ETA_30740
symbol: ETA_30740
gene_biotype: protein_coding
description:
  Putative transcriptional regulator, LysR family; silverDB:etchr03061; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: ETA_30750
symbol: yjcE
gene_biotype: protein_coding
description:
  Putative Na(+)/H(+) exchanger YjcE; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.


ensembl_gene_id: ETA_30850
symbol: ssb
gene_biotype: protein_coding
description:
  Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.


ensembl_gene_id: ETA_30860
symbol: uvrA
gene_biotype: protein_coding
description:
  UvrABC system protein A (Excinuclease ABC subunit A); The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.


ensembl_gene_id: ETA_30940
symbol: dnaB
gene_biotype: protein_coding
description:
  Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily.


ensembl_gene_id: ETA_30970
symbol: dusA
gene_biotype: protein_coding
description:
  tRNA-dihydrouridine synthase A; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily.


ensembl_gene_id: ETA_30990
symbol: zur
gene_biotype: protein_coding
description:
  Zinc uptake regulation protein (Zinc uptake regulator); silverDB:etchr03086; Belongs to the Fur family.


ensembl_gene_id: ETA_31010
symbol: lexA
gene_biotype: protein_coding
description:
  LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'. In the presence of single- stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.


ensembl_gene_id: ETA_31020
symbol: dgkA
gene_biotype: protein_coding
description:
  Diacylglycerol kinase; Recycling of diacylglycerol produced during the turnover of membrane phospholipid.


ensembl_gene_id: ETA_31040
symbol: ubiA
gene_biotype: protein_coding
description:
  4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.


ensembl_gene_id: ETA_31050
symbol: ubiC
gene_biotype: protein_coding
description:
  Chorismate--pyruvate lyase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.


ensembl_gene_id: ETA_31110
symbol: pgi
gene_biotype: protein_coding
description:
  Glucose-6-phosphate isomerase (Phosphoglucose isomerase); silverDB:etchr03098; Belongs to the GPI family.


ensembl_gene_id: ETA_31150
symbol: ETA_31150
gene_biotype: protein_coding
description:
  ABC transporter, ATP binding component; silverDB:etchr03102; Belongs to the ABC transporter superfamily.


ensembl_gene_id: ETA_31200
symbol: metA
gene_biotype: protein_coding
description:
  Homoserine O-succinyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine; Belongs to the MetA family.


ensembl_gene_id: ETA_31230
symbol: aroE
gene_biotype: protein_coding
description:
  Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).


ensembl_gene_id: ETA_31280
symbol: def
gene_biotype: protein_coding
description:
  Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.


ensembl_gene_id: ETA_31290
symbol: fmt
gene_biotype: protein_coding
description:
  10-formyltetrahydrofolate:L-methionyl-tRNA (FMet) N-formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.


ensembl_gene_id: ETA_31320
symbol: mscL
gene_biotype: protein_coding
description:
  Large-conductance mechanosensitive channel; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.


ensembl_gene_id: ETA_31380
symbol: rpoA
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: ETA_31390
symbol: rpsD
gene_biotype: protein_coding
description:
  30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.


ensembl_gene_id: ETA_31400
symbol: rpsK
gene_biotype: protein_coding
description:
  30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.


ensembl_gene_id: ETA_31410
symbol: rpsM
gene_biotype: protein_coding
description:
  30S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family.


ensembl_gene_id: ETA_31430
symbol: secY
gene_biotype: protein_coding
description:
  Preprotein translocase SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.


ensembl_gene_id: ETA_31440
symbol: rplO
gene_biotype: protein_coding
description:
  50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.


ensembl_gene_id: ETA_31460
symbol: rpsE
gene_biotype: protein_coding
description:
  30S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.


ensembl_gene_id: ETA_31470
symbol: rplR
gene_biotype: protein_coding
description:
  50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.


ensembl_gene_id: ETA_31480
symbol: rplF
gene_biotype: protein_coding
description:
  50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.


ensembl_gene_id: ETA_31490
symbol: rpsH
gene_biotype: protein_coding
description:
  30S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.


ensembl_gene_id: ETA_31500
symbol: rpsN
gene_biotype: protein_coding
description:
  30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family.


ensembl_gene_id: ETA_31510
symbol: rplE
gene_biotype: protein_coding
description:
  50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.


ensembl_gene_id: ETA_31520
symbol: rplX
gene_biotype: protein_coding
description:
  50S ribosomal protein L24; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.


ensembl_gene_id: ETA_31530
symbol: rplN
gene_biotype: protein_coding
description:
  50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.


ensembl_gene_id: ETA_31540
symbol: rpsQ
gene_biotype: protein_coding
description:
  30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.


ensembl_gene_id: ETA_31550
symbol: rpmC
gene_biotype: protein_coding
description:
  50S ribosomal protein L29; silverDB:etchr03141; Belongs to the universal ribosomal protein uL29 family.


ensembl_gene_id: ETA_31560
symbol: rplP
gene_biotype: protein_coding
description:
  50S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.


ensembl_gene_id: ETA_31570
symbol: rpsC
gene_biotype: protein_coding
description:
  30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.


ensembl_gene_id: ETA_31580
symbol: rplV
gene_biotype: protein_coding
description:
  50S ribosomal protein L22; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).


ensembl_gene_id: ETA_31590
symbol: rpsS
gene_biotype: protein_coding
description:
  30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.


ensembl_gene_id: ETA_31600
symbol: rplB
gene_biotype: protein_coding
description:
  50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.


ensembl_gene_id: ETA_31610
symbol: rplW
gene_biotype: protein_coding
description:
  50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.


ensembl_gene_id: ETA_31620
symbol: rplD
gene_biotype: protein_coding
description:
  50S ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.


ensembl_gene_id: ETA_31640
symbol: rplC
gene_biotype: protein_coding
description:
  50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.


ensembl_gene_id: ETA_31650
symbol: rpsJ
gene_biotype: protein_coding
description:
  30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.


ensembl_gene_id: ETA_31670
symbol: fusA
gene_biotype: protein_coding
description:
  Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...]


ensembl_gene_id: ETA_31680
symbol: rpsG
gene_biotype: protein_coding
description:
  30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.


ensembl_gene_id: ETA_31700
symbol: tusB
gene_biotype: protein_coding
description:
  tRNA 2-thiouridine synthesizing protein B, protein TusB; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.


ensembl_gene_id: ETA_31710
symbol: tusC
gene_biotype: protein_coding
description:
  tRNA 2-thiouridine synthesizing protein C, protein TusC; silverDB:etchr03157; Belongs to the DsrF/TusC family.


ensembl_gene_id: ETA_31720
symbol: tusD
gene_biotype: protein_coding
description:
  Sulfurtransferase TusD (tRNA 2-thiouridine synthesizing protein D); Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE.


ensembl_gene_id: ETA_31780
symbol: kefB
gene_biotype: protein_coding
description:
  Glutathione-regulated potassium-efflux system protein KefB (K(+)/H(+) antiporter); Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport.


ensembl_gene_id: ETA_31790
symbol: kefG
gene_biotype: protein_coding
description:
  Glutathione-regulated potassium-efflux system ancillary protein KefG; Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefB.


ensembl_gene_id: ETA_31830
symbol: tauB
gene_biotype: protein_coding
description:
  Taurine transport ATP-binding protein; Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Taurine importer (TC 3.A.1.17.1) family.


ensembl_gene_id: ETA_31920
symbol: argD
gene_biotype: protein_coding
description:
  Acetylornithine aminotransferase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.


ensembl_gene_id: ETA_31940
symbol: ppiA
gene_biotype: protein_coding
description:
  Peptidyl-prolyl cis-trans isomerase A (Rotamase A); PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.


ensembl_gene_id: ETA_32000
symbol: trpS
gene_biotype: protein_coding
description:
  Tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: ETA_32010
symbol: gph
gene_biotype: protein_coding
description:
  Phosphoglycolate phosphatase; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.


ensembl_gene_id: ETA_32020
symbol: rpe
gene_biotype: protein_coding
description:
  Ribulose-phosphate 3-epimerase (Pentose-5-phosphate 3-epimerase); silverDB:etchr03188; Belongs to the ribulose-phosphate 3-epimerase family.


ensembl_gene_id: ETA_32050
symbol: aroB
gene_biotype: protein_coding
description:
  3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.


ensembl_gene_id: ETA_32060
symbol: aroK
gene_biotype: protein_coding
description:
  Shikimate kinase I; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.


ensembl_gene_id: ETA_32160
symbol: hslO
gene_biotype: protein_coding
description:
  Heat shock protein 33; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.


ensembl_gene_id: ETA_32170
symbol: pckA
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate carboxykinase (PEP carboxykinase); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.


ensembl_gene_id: ETA_32210
symbol: greB
gene_biotype: protein_coding
description:
  Transcription elongation factor GreB; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.


ensembl_gene_id: ETA_32260
symbol: bioH
gene_biotype: protein_coding
description:
  Carboxylesterase (Biotin synthesis protein BioH); The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.


ensembl_gene_id: ETA_32280
symbol: gntY
gene_biotype: protein_coding
description:
  Putative membrane-bound protein GntY; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.


ensembl_gene_id: ETA_32410
symbol: glpE
gene_biotype: protein_coding
description:
  Thiosulfate sulfurtransferase GlpE; Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.


ensembl_gene_id: ETA_32420
symbol: glpD
gene_biotype: protein_coding
description:
  Sn-glycerol-3-phosphate dehydrogenase; silverDB:etchr03228; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.


ensembl_gene_id: ETA_32450
symbol: glgP
gene_biotype: protein_coding
description:
  Glycogen phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.


ensembl_gene_id: ETA_32470
symbol: glgC
gene_biotype: protein_coding
description:
  Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.


ensembl_gene_id: ETA_32480
symbol: glgX
gene_biotype: protein_coding
description:
  Glycogen debranching enzyme; Removes maltotriose and maltotetraose chains that are attached by 1,6-alpha-linkage to the limit dextrin main chain, generating a debranched limit dextrin.


ensembl_gene_id: ETA_32490
symbol: glgB
gene_biotype: protein_coding
description:
  1,4-alpha-glucan branching enzyme (Glycogen branching enzyme); Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.


ensembl_gene_id: ETA_32500
symbol: asd
gene_biotype: protein_coding
description:
  Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.


ensembl_gene_id: ETA_32620
symbol: ugpC
gene_biotype: protein_coding
description:
  SN-glycerol-3-phosphate transport ATP-binding protein; Part of the ABC transporter complex UgpABCE involved in sn- glycerol-3-phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. sn-glycerol-3- phosphate importer (TC 3.A.1.1.3) family.


ensembl_gene_id: ETA_32630
symbol: ugpE
gene_biotype: protein_coding
description:
  Sn-glycerol-3-phosphate transport system, permease protein; Part of the binding-protein-dependent transport system for sn-glycerol-3-phosphate; probably responsible for the translocation of the substrate across the membrane.


ensembl_gene_id: ETA_32680
symbol: livF
gene_biotype: protein_coding
description:
  High-affinity branched-chain amino acid transport ATP-binding protein; silverDB:etchr03254; Belongs to the ABC transporter superfamily.


ensembl_gene_id: ETA_32700
symbol: livM
gene_biotype: protein_coding
description:
  High-affinity branched-chain amino acid transport system permease protein; silverDB:etchr03256; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: ETA_32710
symbol: livH
gene_biotype: protein_coding
description:
  High-affinity branched-chain amino acid transport system permease protein; silverDB:etchr03257; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: ETA_32730
symbol: yhhK
gene_biotype: protein_coding
description:
  Conserved hypothetical protein YhhK; Controls both the activation and catalytic activity of PanD in a coenzyme A (CoA)-dependent fashion; Belongs to the PanZ/PanM family.


ensembl_gene_id: ETA_32740
symbol: rpoH
gene_biotype: protein_coding
description:
  RNA polymerase sigma-32 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.


ensembl_gene_id: ETA_32750
symbol: ftsX
gene_biotype: protein_coding
description:
  Cell division protein; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.


ensembl_gene_id: ETA_32770
symbol: ftsY
gene_biotype: protein_coding
description:
  Cell division protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.


ensembl_gene_id: ETA_32780
symbol: yhhF
gene_biotype: protein_coding
description:
  Putative methylase YhhF; Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle; Belongs to the methyltransferase superfamily. RsmD family.


ensembl_gene_id: ETA_32830
symbol: tusA
gene_biotype: protein_coding
description:
  Sulfurtransferase (tRNA 2-thiouridine synthesizing protein A); Sulfur carrier protein involved in sulfur trafficking in the cell. Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA. Interacts with IscS and stimulates its cysteine desulfurase activity. Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation. Also appears to be involved in sulfur transfer for the  [...]


ensembl_gene_id: ETA_32840
symbol: ETA_32840
gene_biotype: protein_coding
description:
  Putative membrane protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.


ensembl_gene_id: ETA_32860
symbol: iolE
gene_biotype: protein_coding
description:
  Myo-inositol catabolism protein (2-keto-myo-inositol dehydratase); Catalyzes the dehydration of inosose (2-keto-myo-inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D-(3,5/4)- trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi-inositol). Belongs to the IolE/MocC family.


ensembl_gene_id: ETA_32880
symbol: iolG
gene_biotype: protein_coding
description:
  Myo-inositol 2-dehydrogenase; Involved in the oxidation of myo-inositol (MI) to 2-keto-myo- inositol (2KMI or 2-inosose).


ensembl_gene_id: ETA_32890
symbol: iolD
gene_biotype: protein_coding
description:
  Myo-inositol catabolism protein, malonic semialdehyde oxidative decarboxylase; silverDB:etchr03275; Belongs to the TPP enzyme family.


ensembl_gene_id: ETA_33210
symbol: yhiQ
gene_biotype: protein_coding
description:
  Conserved hypothetical protein YhiQ; Specifically methylates the guanosine in position 1516 of 16S rRNA.


ensembl_gene_id: ETA_33240
symbol: yhiR
gene_biotype: protein_coding
description:
  Conserved hypothetical protein YhiR; Specifically methylates the adenine in position 2030 of 23S rRNA.


ensembl_gene_id: ETA_33250
symbol: rnz
gene_biotype: protein_coding
description:
  Ribonuclease Z; Zinc phosphodiesterase, which has both exoribonuclease and endoribonuclease activities.


ensembl_gene_id: ETA_33420
symbol: ETA_33420
gene_biotype: protein_coding
description:
  Putative transcriptional regulator; silverDB:etchr03328; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: ETA_33520
symbol: ETA_33520
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; silverDB:etchr03338; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: ETA_33630
symbol: kdpC
gene_biotype: protein_coding
description:
  Potassium-transporting ATPase, C chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.


ensembl_gene_id: ETA_33640
symbol: kdpB
gene_biotype: protein_coding
description:
  Potassium-transporting ATPase, B chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.


ensembl_gene_id: ETA_33650
symbol: kdpA
gene_biotype: protein_coding
description:
  ATPase of high-affinity potassium transport system, A chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane.


ensembl_gene_id: ETA_33770
symbol: mntP
gene_biotype: protein_coding
description:
  Putative membrane protein; Probably functions as a manganese efflux pump. Belongs to the MntP (TC 9.B.29) family.


ensembl_gene_id: ETA_33860
symbol: dctA
gene_biotype: protein_coding
description:
  Aerobic C4-dicarboxylate transport protein; Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane. Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: ETA_33910
symbol: bscB
gene_biotype: protein_coding
description:
  Cyclic di-GMP-binding protein, Cellulose synthase operon protein B; Binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP); Belongs to the AcsB/BcsB family.


ensembl_gene_id: ETA_33920
symbol: bscA
gene_biotype: protein_coding
description:
  Cellulose synthase, Cellulose synthase operon protein A; Catalytic subunit of cellulose synthase. It polymerizes uridine 5'-diphosphate glucose to cellulose.


ensembl_gene_id: ETA_33950
symbol: dppF
gene_biotype: protein_coding
description:
  Dipeptide transport ATP-binding protein; silverDB:etchr03381; Belongs to the ABC transporter superfamily.


ensembl_gene_id: ETA_33960
symbol: dppD
gene_biotype: protein_coding
description:
  Dipeptide transport ATP-binding protein; silverDB:etchr03382; Belongs to the ABC transporter superfamily.


ensembl_gene_id: ETA_34110
symbol: yiaH
gene_biotype: protein_coding
description:
  Putative inner membrane protein YiaH; Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units.


ensembl_gene_id: ETA_34270
symbol: ETA_34270
gene_biotype: protein_coding
description:
  Ribose transport system, permease protein; silverDB:etchr03413; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: ETA_34290
symbol: sodA
gene_biotype: protein_coding
description:
  Manganese superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.


ensembl_gene_id: ETA_34300
symbol: ETA_34300
gene_biotype: protein_coding
description:
  Putative aminotransferase; silverDB:etchr03416; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: ETA_34320
symbol: fdhD
gene_biotype: protein_coding
description:
  Formate dehydrogenase-N influencing protein; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.


ensembl_gene_id: ETA_34330
symbol: fdhE
gene_biotype: protein_coding
description:
  Putative formate dehydrogenase formation protein; Necessary for formate dehydrogenase activity. Belongs to the FdhE family.


ensembl_gene_id: ETA_34410
symbol: tkrA
gene_biotype: protein_coding
description:
  2-ketogluconate reductase; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily.


ensembl_gene_id: ETA_34460
symbol: ibpA
gene_biotype: protein_coding
description:
  Small heat shock protein IbpA (16 kDa heat shock protein A); Associates with aggregated proteins, together with IbpB, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress. Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE. Its activity is ATP-independent.


ensembl_gene_id: ETA_34500
symbol: gyrB
gene_biotype: protein_coding
description:
  DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.


ensembl_gene_id: ETA_34510
symbol: recF
gene_biotype: protein_coding
description:
  DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.


ensembl_gene_id: ETA_34520
symbol: dnaN
gene_biotype: protein_coding
description:
  DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of  [...]


ensembl_gene_id: ETA_34530
symbol: dnaA
gene_biotype: protein_coding
description:
  Chromosomal replication initiator protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.


ensembl_gene_id: ETA_34540
symbol: rpmH
gene_biotype: protein_coding
description:
  50S ribosomal protein L34; silverDB:etchr03440; Belongs to the bacterial ribosomal protein bL34 family.


ensembl_gene_id: ETA_34550
symbol: rnpA
gene_biotype: protein_coding
description:
  Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.


ensembl_gene_id: ETA_34560
symbol: oxaA
gene_biotype: protein_coding
description:
  Inner membrane protein OxaA; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.


ensembl_gene_id: ETA_34570
symbol: trmE
gene_biotype: protein_coding
description:
  tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.


ensembl_gene_id: ETA_34580
symbol: yieE
gene_biotype: protein_coding
description:
  Conserved hypothetical protein YieE; silverDB:etchr03444; Belongs to the P-Pant transferase superfamily.


ensembl_gene_id: ETA_34610
symbol: phoU
gene_biotype: protein_coding
description:
  IS1 transposase, fragment; Part of the phosphate (Pho) regulon, which plays a key role in phosphate homeostasis. PhoU is essential for the repression of the Pho regulon at high phosphate conditions.


ensembl_gene_id: ETA_34620
symbol: pstB
gene_biotype: protein_coding
description:
  Phosphate import ATP-binding protein PstB (Phosphate-transporting ATPase); Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.


ensembl_gene_id: ETA_34640
symbol: pstC
gene_biotype: protein_coding
description:
  Phosphate transport system permease protein; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: ETA_34650
symbol: pstS
gene_biotype: protein_coding
description:
  Periplasmic phosphate binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import; Belongs to the PstS family.


ensembl_gene_id: ETA_34670
symbol: lsc
gene_biotype: protein_coding
description:
  Levansucrase (beta-D-fructofuranosyl transferase); silverDB:etchr03452; Belongs to the glycosyl hydrolase 68 family.


ensembl_gene_id: ETA_34720
symbol: glmS
gene_biotype: protein_coding
description:
  Glucosamine-fructose-6-phosphate aminotransferase [isomerizing]; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.


ensembl_gene_id: ETA_34730
symbol: glmU
gene_biotype: protein_coding
description:
  Bifunctional protein GlmU [Includes: UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferas [...]


ensembl_gene_id: ETA_34740
symbol: atpC
gene_biotype: protein_coding
description:
  ATP synthase, F1 complex, epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane.


ensembl_gene_id: ETA_34750
symbol: atpD
gene_biotype: protein_coding
description:
  ATP synthase, F1 complex, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family.


ensembl_gene_id: ETA_34760
symbol: atpG
gene_biotype: protein_coding
description:
  ATP synthase, F1 complex, gamma subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.


ensembl_gene_id: ETA_34770
symbol: atpA
gene_biotype: protein_coding
description:
  ATP synthase, F1 complex, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family.


ensembl_gene_id: ETA_34780
symbol: atpH
gene_biotype: protein_coding
description:
  ATP synthase, F1 complex, delta subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family.


ensembl_gene_id: ETA_34790
symbol: atpF
gene_biotype: protein_coding
description:
  ATP synthase, F0 complex, b subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.


ensembl_gene_id: ETA_34800
symbol: atpE
gene_biotype: protein_coding
description:
  ATP synthase, F0 complex, c subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.


ensembl_gene_id: ETA_34810
symbol: atpB
gene_biotype: protein_coding
description:
  ATP synthase, F0 complex, a subunit; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.


ensembl_gene_id: ETA_34830
symbol: gidB
gene_biotype: protein_coding
description:
  Methyltransferase GidB (Glucose-inhibited division protein B); Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.


ensembl_gene_id: ETA_34840
symbol: gidA
gene_biotype: protein_coding
description:
  tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family.


