# geneInfo

ensembl_gene_id: PROVRUST_04507
symbol: rusA
gene_biotype: protein_coding
description:
  Crossover junction endodeoxyribonuclease RusA; Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC; Belongs to the rusA family.


ensembl_gene_id: PROVRUST_04516
symbol: EFB74027.1
gene_biotype: protein_coding
description:
  DNA-binding helix-turn-helix protein; KEGG: fnu:FN1589 0.0030 LexA repressor K01356; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_04517
symbol: EFB74028.1
gene_biotype: protein_coding
description:
  Hypothetical protein; KEGG: efa:EF0053 0.0025 dnaQ; DNA polymerase III, epsilon subunit K02342; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_04519
symbol: csrA
gene_biotype: protein_coding
description:
  Carbon storage regulator; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).


ensembl_gene_id: PROVRUST_04525
symbol: cspD
gene_biotype: protein_coding
description:
  Cold shock domain protein CspD; KEGG: net:Neut_1619 0.0044 ribonuclease R K01147; Psort location: Cytoplasmic, score: 9.26.


ensembl_gene_id: PROVRUST_04527
symbol: KdgR
gene_biotype: protein_coding
description:
  Transcriptional regulator, IclR family, C-terminal domain protein; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_04529
symbol: CodB_2
gene_biotype: protein_coding
description:
  Permease, cytosine/purine, uracil, thiamine, allantoin family; KEGG: aci:ACIAD2501 6.2e-09 putative two-component sensor kinase; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_04531
symbol: macB
gene_biotype: protein_coding
description:
  ABC transporter, ATP-binding protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.


ensembl_gene_id: PROVRUST_04532
symbol: MacA_4
gene_biotype: protein_coding
description:
  Efflux transporter, RND family, MFP subunit; KEGG: spj:MGAS2096_Spy1515 0.0096 accB; biotin carboxyl carrier protein of acetyl-CoA carboxylase K01961; Psort location: CytoplasmicMembrane, score: 8.02; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: PROVRUST_04536
symbol: EFB74047.1
gene_biotype: protein_coding
description:
  NAD dependent epimerase/dehydratase family protein; KEGG: eci:UTI89_C0872 6.6e-151 ybjT; hypothetical protein YbjT K00329:K00356; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_04537
symbol: artP
gene_biotype: protein_coding
description:
  KEGG: plu:plu1588 8.0e-107 artP; arginine transport ATP-binding protein ArtP K02028; Psort location: CytoplasmicMembrane, score: 7.88.


ensembl_gene_id: PROVRUST_04538
symbol: ArtI
gene_biotype: protein_coding
description:
  KEGG: eci:UTI89_C2121 9.0e-28 fliY; cystine-binding periplasmic protein precursor K02030:K02424; Psort location: Periplasmic, score: 10.00; Belongs to the bacterial solute-binding protein 3 family.


ensembl_gene_id: PROVRUST_04539
symbol: ArtQ
gene_biotype: protein_coding
description:
  KEGG: eca:ECA0855 5.6e-19 ABC transporter permease protein K02028; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_04540
symbol: artM
gene_biotype: protein_coding
description:
  KEGG: hpa:HPAG1_0922 2.4e-18 amino acid ABC transporter, permease protein; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_04541
symbol: EFB74052.1
gene_biotype: protein_coding
description:
  Hypothetical protein; KEGG: wbr:WGLp018 0.00013 surA; parvulin-like peptidyl-prolyl isomerase K03771; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_04543
symbol: rumB
gene_biotype: protein_coding
description:
  23S rRNA (uracil-5-)-methyltransferase RumB; Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.


ensembl_gene_id: PROVRUST_04547
symbol: grxA
gene_biotype: protein_coding
description:
  Glutaredoxin, GrxA family; KEGG: eci:UTI89_C4152 1.4e-08 grxC; glutaredoxin 3 K03676; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_04549
symbol: YbjG
gene_biotype: protein_coding
description:
  PAP2 family protein; KEGG: btk:BT9727_2194 9.2e-08 probable phosphatase, PAP2 superfamily; possible bacitracin transport permease K01112; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_04551
symbol: SdaB
gene_biotype: protein_coding
description:
  KEGG: ssn:SSO_2954 5.9e-198 sdaB; L-serine dehydratase K01752; Belongs to the iron-sulfur dependent L-serine dehydratase family.


ensembl_gene_id: PROVRUST_04553
symbol: DacC
gene_biotype: protein_coding
description:
  Serine-type D-Ala-D-Ala carboxypeptidase; KEGG: plu:plu1573 4.2e-149 dacC; penicillin-binding protein 6 precursor (D-alanyl-D-alanine carboxypeptidase fraction C) (DD-pept (DD-carboxypeptidase) (PBP-6)idase) K07258; Psort location: CytoplasmicMembrane, score: 9.98; Belongs to the peptidase S11 family.


ensembl_gene_id: PROVRUST_04555
symbol: GstB_1
gene_biotype: protein_coding
description:
  Glutathione S-transferase, C-terminal domain protein; KEGG: xcc:XCC3766 1.2e-48 gst; glutathione S-transferase K00799.


ensembl_gene_id: PROVRUST_04557
symbol: hisG
gene_biotype: protein_coding
description:
  ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.


ensembl_gene_id: PROVRUST_04558
symbol: hisD
gene_biotype: protein_coding
description:
  Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.


ensembl_gene_id: PROVRUST_04559
symbol: hisC
gene_biotype: protein_coding
description:
  Histidinol-phosphate transaminase; KEGG: plu:plu1569 1.2e-133 hisD; histidinol dehydrogenase K00013:K00817; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.


ensembl_gene_id: PROVRUST_04560
symbol: hisB
gene_biotype: protein_coding
description:
  Histidinol-phosphatase; KEGG: eca:ECA2585 1.1e-157 hisB; imidazole glycerol-phosphate dehydratase/histidinol phosphatase K01089:K01693; In the N-terminal section; belongs to the histidinol- phosphatase family.


ensembl_gene_id: PROVRUST_04561
symbol: hisH
gene_biotype: protein_coding
description:
  Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.


ensembl_gene_id: PROVRUST_04562
symbol: hisA
gene_biotype: protein_coding
description:
  KEGG: eca:ECA2587 9.0e-99 hisA; 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase K01814; Psort location: Cytoplasmic, score: 9.26.


ensembl_gene_id: PROVRUST_04563
symbol: hisF
gene_biotype: protein_coding
description:
  Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.


ensembl_gene_id: PROVRUST_04564
symbol: hisE
gene_biotype: protein_coding
description:
  phosphoribosyl-ATP diphosphatase; KEGG: ype:YPO1542 2.8e-81 hisI, hisIE; histidine biosynthesis bifunctional protein [includes: phosphoribosyl-amp cyclohydrolase K01496:K01523; Psort location: Cytoplasmic, score: 9.97; In the N-terminal section; belongs to the PRA-CH family.


ensembl_gene_id: PROVRUST_04568
symbol: EFB74078.1
gene_biotype: protein_coding
description:
  Drug resistance transporter, Bcr/CflA subfamily; KEGG: ani:AN1180.2 4.0e-09 hypothetical protein K04428; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_04570
symbol: gnd
gene_biotype: protein_coding
description:
  Phosphogluconate dehydrogenase (decarboxylating); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.


ensembl_gene_id: PROVRUST_04571
symbol: YoaE
gene_biotype: protein_coding
description:
  CBS domain protein; KEGG: eci:UTI89_C0656 4.7e-24 ybeX; putative transport protein K06189; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_04572
symbol: EFB74082.1
gene_biotype: protein_coding
description:
  Hypothetical protein; KEGG: cal:orf19.2410 0.0013 IMH1; involved in vesicular transport K01553; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_04576
symbol: udk
gene_biotype: protein_coding
description:
  Uridine kinase; KEGG: plu:plu1556 4.6e-95 udk; uridine kinase (uridine monophosphokinase) (pyrimidine ribonucleoside kinase) K00876; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_04577
symbol: HtpX_1
gene_biotype: protein_coding
description:
  Peptidase, M48 family; KEGG: cbu:CBU_0546 2.7e-58 htpX; heat shock protein HtpX K03799; Psort location: CytoplasmicMembrane, score: 9.46.


ensembl_gene_id: PROVRUST_04580
symbol: YlxH
gene_biotype: protein_coding
description:
  Putative ATPase; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.


ensembl_gene_id: PROVRUST_04581
symbol: metG
gene_biotype: protein_coding
description:
  methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.


ensembl_gene_id: PROVRUST_04582
symbol: YohJ
gene_biotype: protein_coding
description:
  LrgA family protein; KEGG: btk:BT9727_3424 1.3e-12 murein hydrolase exporter K06518; Psort location: CytoplasmicMembrane, score: 9.46.


ensembl_gene_id: PROVRUST_04583
symbol: YohK
gene_biotype: protein_coding
description:
  TIGR00659 family protein; KEGG: bcz:BCZK3376 4.2e-30 murein hydrolase export regulator K01238; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_04584
symbol: cdd
gene_biotype: protein_coding
description:
  Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.


ensembl_gene_id: PROVRUST_04589
symbol: maeA
gene_biotype: protein_coding
description:
  Malic enzyme, NAD binding domain protein; KEGG: plu:plu1546 3.1e-272 maeA; malate dehydrogenase (oxaloacetate-decarboxylating) K00027.


ensembl_gene_id: PROVRUST_04590
symbol: AarA
gene_biotype: protein_coding
description:
  Peptidase, S54 family; KEGG: eci:UTI89_C0653 1.7e-41 hypothetical protein; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_04593
symbol: folE
gene_biotype: protein_coding
description:
  GTP cyclohydrolase I; KEGG: ypm:YP_1395 1.0e-97 folE; GTP cyclohydrolase I K01495; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_04594
symbol: MoeA
gene_biotype: protein_coding
description:
  Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.


ensembl_gene_id: PROVRUST_04595
symbol: moeB
gene_biotype: protein_coding
description:
  KEGG: eci:UTI89_C0829 1.4e-95 moeB; molybdopterin biosynthesis protein MoeB K03751; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_04597
symbol: EFB74107.1
gene_biotype: protein_coding
description:
  Putative alkylphosphonate utilization operon protein PhnA; KEGG: eci:UTI89_C4702 1.5e-50 phnA; hypothetical protein PhnA K06193.


ensembl_gene_id: PROVRUST_04598
symbol: YheS_3
gene_biotype: protein_coding
description:
  ABC transporter, ATP-binding protein; KEGG: eci:UTI89_C0824 6.0e-244 ybiT; hypothetical ABC transporter ATP-binding protein YbiT K01957; Psort location: CytoplasmicMembrane, score: 9.82.


ensembl_gene_id: PROVRUST_04599
symbol: YvdD
gene_biotype: protein_coding
description:
  TIGR00730 family protein; KEGG: bcl:ABC1937 4.1e-48 lysine decarboxylase K01582; Belongs to the LOG family.


ensembl_gene_id: PROVRUST_04600
symbol: RhtA
gene_biotype: protein_coding
description:
  Putative membrane protein; KEGG: pae:PA1977 9.4e-06 sensor protein GLPS; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_04601
symbol: Dps
gene_biotype: protein_coding
description:
  Ferritin-like protein; KEGG: eci:UTI89_C0816 2.4e-59 dps; stationary phase nucleoid protein Dps K04047; Psort location: Cytoplasmic, score: 8.96; Belongs to the Dps family.


ensembl_gene_id: PROVRUST_04602
symbol: EFB74112.1
gene_biotype: protein_coding
description:
  Hypothetical protein; KEGG: ypn:YPN_2771 1.1e-91 ATP-dependent helicase DinG K03722; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_04603
symbol: dinG
gene_biotype: protein_coding
description:
  KEGG: plu:plu1524 1.2e-176 dinG; probable ATP-dependent helicase (DNA-damage-inducible protein G) K03722; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_04605
symbol: SseA
gene_biotype: protein_coding
description:
  Rhodanese-like protein; KEGG: plu:plu1522 1.3e-81 sseA; 3-mercaptopyruvate sulfurtransferase (rhodanese-like protein) K01010.


ensembl_gene_id: PROVRUST_04608
symbol: EFB74118.1
gene_biotype: protein_coding
description:
  Transglycosylase associated protein; KEGG: cgl:NCgl1946 0.00055 cgl2022; CDP-diglyceride synthetase K00981; Psort location: CytoplasmicMembrane, score: 9.46.


ensembl_gene_id: PROVRUST_04609
symbol: dusC
gene_biotype: protein_coding
description:
  tRNA-dihydrouridine synthase C; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs. Belongs to the Dus family. DusC subfamily.


ensembl_gene_id: PROVRUST_04610
symbol: rhlE
gene_biotype: protein_coding
description:
  ATP-dependent RNA helicase RhlE; DEAD-box RNA helicase involved in ribosome assembly. Has RNA- dependent ATPase activity and unwinds double-stranded RNA.


ensembl_gene_id: PROVRUST_04612
symbol: MacA_3
gene_biotype: protein_coding
description:
  Auxiliary transport protein, membrane fusion protein (MFP) family protein; Psort location: CytoplasmicMembrane, score: 8.02.


ensembl_gene_id: PROVRUST_04613
symbol: YbhF_1
gene_biotype: protein_coding
description:
  ABC transporter, ATP-binding protein; KEGG: rru:Rru_A1792 1.8e-173 ABC transporter component K01990.


ensembl_gene_id: PROVRUST_04614
symbol: YbhS
gene_biotype: protein_coding
description:
  ABC-2 type transporter; KEGG: fal:FRAAL1796 1.3e-14 putative ABC transporter ATP-binding subunit; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_04615
symbol: YbhR
gene_biotype: protein_coding
description:
  ABC-2 type transporter; KEGG: fal:FRAAL1796 3.0e-08 putative ABC transporter ATP-binding subunit; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_04616
symbol: EFB74126.1
gene_biotype: protein_coding
description:
  Methyltransferase domain protein; KEGG: mbo:Mb2655 7.6e-31 possible methyltransferase (methylase) K00599; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_04618
symbol: EFB74128.1
gene_biotype: protein_coding
description:
  ABC transporter, ATP-binding protein; KEGG: hin:HI1470 1.2e-50 fepC; putative iron transport system ATP-binding protein K02013.


ensembl_gene_id: PROVRUST_04619
symbol: EFB74129.1
gene_biotype: protein_coding
description:
  Iron chelate uptake ABC transporter, FeCT family, permease protein; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: PROVRUST_04627
symbol: moaC
gene_biotype: protein_coding
description:
  Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.


ensembl_gene_id: PROVRUST_04628
symbol: moaA
gene_biotype: protein_coding
description:
  Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.


ensembl_gene_id: PROVRUST_04629
symbol: HxuC_1
gene_biotype: protein_coding
description:
  TonB-dependent heme/hemoglobin receptor family protein; Psort location: OuterMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_04631
symbol: FecI_2
gene_biotype: protein_coding
description:
  KEGG: chu:CHU_3562 5.7e-10 rpoE; RNA polymerase sigma-70 factor, ECF subfamily K00960; Psort location: Cytoplasmic, score: 9.26.


ensembl_gene_id: PROVRUST_04633
symbol: EFB74143.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family.


ensembl_gene_id: PROVRUST_04634
symbol: DctD
gene_biotype: protein_coding
description:
  Response regulator receiver domain protein; KEGG: eci:UTI89_C2502 3.3e-30 atoC; acetoacetate metabolism regulatory protein AtoC K07714; Psort location: Cytoplasmic, score: 9.97.


ensembl_gene_id: PROVRUST_04635
symbol: pgtB
gene_biotype: protein_coding
description:
  KEGG: sec:SC2398 3.2e-174 pgtB; phosphoglycerate transport: protein for signal transmission K08475; Psort location: CytoplasmicMembrane, score: 9.82.


ensembl_gene_id: PROVRUST_04639
symbol: uvrB
gene_biotype: protein_coding
description:
  Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]


ensembl_gene_id: PROVRUST_04640
symbol: bioD
gene_biotype: protein_coding
description:
  Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. Belongs to the dethiobiotin synthetase family.


ensembl_gene_id: PROVRUST_04641
symbol: bioC
gene_biotype: protein_coding
description:
  Biotin biosynthesis protein BioC; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.


ensembl_gene_id: PROVRUST_04642
symbol: bioF
gene_biotype: protein_coding
description:
  8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.


ensembl_gene_id: PROVRUST_04643
symbol: bioB
gene_biotype: protein_coding
description:
  Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.


ensembl_gene_id: PROVRUST_04644
symbol: bioA
gene_biotype: protein_coding
description:
  Adenosylmethionine-8-amino-7-oxononanoate transaminase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.


ensembl_gene_id: PROVRUST_04646
symbol: YidA_1
gene_biotype: protein_coding
description:
  Cof-like hydrolase; KEGG: aha:AHA_3603 2.0e-46 phosphatase YbhA K01112; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_04647
symbol: modC
gene_biotype: protein_coding
description:
  Molybdate ABC transporter, ATP-binding protein; Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Molybdate importer (TC 3.A.1.8) family.


ensembl_gene_id: PROVRUST_04648
symbol: modB
gene_biotype: protein_coding
description:
  Molybdate ABC transporter, permease protein; Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: PROVRUST_04649
symbol: modA
gene_biotype: protein_coding
description:
  Molybdate ABC transporter, periplasmic molybdate-binding protein; Psort location: Periplasmic, score: 9.44.


ensembl_gene_id: PROVRUST_04652
symbol: acrZ
gene_biotype: protein_coding
description:
  Hypothetical protein; AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export.


ensembl_gene_id: PROVRUST_04654
symbol: EFB74164.1
gene_biotype: protein_coding
description:
  KEGG: yps:YPTB1173 3.0e-178 modF, phrA; ABC molybdenum transporter, ATP-binding subunit modF K02017; Psort location: CytoplasmicMembrane, score: 7.88.


ensembl_gene_id: PROVRUST_04655
symbol: gpmA
gene_biotype: protein_coding
description:
  2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.


ensembl_gene_id: PROVRUST_04657
symbol: AroG_1
gene_biotype: protein_coding
description:
  3-deoxy-7-phosphoheptulonate synthase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP).


ensembl_gene_id: PROVRUST_04659
symbol: nadA
gene_biotype: protein_coding
description:
  Quinolinate synthetase complex, A subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate; Belongs to the quinolinate synthase A family. Type 1 subfamily.


ensembl_gene_id: PROVRUST_04660
symbol: EFB74170.1
gene_biotype: protein_coding
description:
  Hypothetical protein; KEGG: plu:plu1458 1.1e-54 unnamed protein product; similar to streptomycin adenyltransferase K05593.


ensembl_gene_id: PROVRUST_04665
symbol: ygbF
gene_biotype: protein_coding
description:
  Tol-pal system protein YbgF; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family.


ensembl_gene_id: PROVRUST_04666
symbol: pal
gene_biotype: protein_coding
description:
  Peptidoglycan-associated lipoprotein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: PROVRUST_04667
symbol: tolB
gene_biotype: protein_coding
description:
  Tol-Pal system beta propeller repeat protein TolB; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.


ensembl_gene_id: PROVRUST_04668
symbol: tolA
gene_biotype: protein_coding
description:
  Protein TolA; KEGG: eci:UTI89_C0735 5.9e-79 tolA; membrane spanning protein TolA K03646; Psort location: CytoplasmicMembrane, score: 8.02.


ensembl_gene_id: PROVRUST_04669
symbol: tolR
gene_biotype: protein_coding
description:
  Putative protein TolR; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolQ, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.


ensembl_gene_id: PROVRUST_04670
symbol: tolQ
gene_biotype: protein_coding
description:
  Protein TolQ; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolR, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.


ensembl_gene_id: PROVRUST_04671
symbol: ybgC
gene_biotype: protein_coding
description:
  Tol-pal system-associated acyl-CoA thioesterase; KEGG: eci:UTI89_C0732 5.1e-41 ybgC; cytoplasmic Tol-Pal protein.


ensembl_gene_id: PROVRUST_04674
symbol: cydB
gene_biotype: protein_coding
description:
  KEGG: plu:plu1450 8.4e-167 cydB; cytochrome D ubiquinol oxidase subunit II (cytochrome BD-I oxidase subunit II) K00426; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_04675
symbol: cydA
gene_biotype: protein_coding
description:
  KEGG: plu:plu1449 5.7e-232 cydA; cytochrome D ubiquinol oxidase subunit I (cytochrome BD-I oxidase subunit I) K00425; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_04676
symbol: sucD
gene_biotype: protein_coding
description:
  succinate-CoA ligase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.


ensembl_gene_id: PROVRUST_04677
symbol: sucC
gene_biotype: protein_coding
description:
  succinate-CoA ligase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.


ensembl_gene_id: PROVRUST_04678
symbol: sucB
gene_biotype: protein_coding
description:
  Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).


ensembl_gene_id: PROVRUST_04679
symbol: sucA
gene_biotype: protein_coding
description:
  KEGG: plu:plu1430 0. sucA; 2-oxoglutarate dehydrogenase E1 component (alpha-ketoglutarate dehydrogenase) K00164; Psort location: Cytoplasmic, score: 9.26.


ensembl_gene_id: PROVRUST_04681
symbol: SdhB
gene_biotype: protein_coding
description:
  Succinate dehydrogenase and fumarate reductase iron-sulfur protein; KEGG: plu:plu1429 1.1e-120 sdhB; succinate dehydrogenase iron sulfur protein K00240; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.


ensembl_gene_id: PROVRUST_04682
symbol: sdhA
gene_biotype: protein_coding
description:
  KEGG: eca:ECA1359 1.6e-300 sdhA; succinate dehydrogenase flavoprotein subunit K00239; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.


ensembl_gene_id: PROVRUST_04683
symbol: sdhD
gene_biotype: protein_coding
description:
  Succinate dehydrogenase, hydrophobic membrane anchor protein; Membrane-anchoring subunit of succinate dehydrogenase (SDH).


ensembl_gene_id: PROVRUST_04684
symbol: sdhC
gene_biotype: protein_coding
description:
  KEGG: spt:SPA2011 1.7e-49 sdhC; succinate dehydrogenase cytochrome b-556 subunit K00241; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_04687
symbol: RipA_1
gene_biotype: protein_coding
description:
  Transcriptional regulator, AraC family; KEGG: ban:BA3869 0.00016 adaA; Ada regulatory protein/6-O-methylguanine-DNA methyltransferase K00567.


ensembl_gene_id: PROVRUST_04688
symbol: YdhC_1
gene_biotype: protein_coding
description:
  Drug resistance transporter, Bcr/CflA subfamily; KEGG: gme:Gmet_0086 9.6e-06 2-acyl-glycerophospho-ethanolamine acyltransferase K05939:K01909; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_04694
symbol: kdpA
gene_biotype: protein_coding
description:
  K+-transporting ATPase, A subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane.


ensembl_gene_id: PROVRUST_04695
symbol: kdpB
gene_biotype: protein_coding
description:
  K+-transporting ATPase, B subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.


ensembl_gene_id: PROVRUST_04696
symbol: kdpC
gene_biotype: protein_coding
description:
  K+-transporting ATPase, C subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.


ensembl_gene_id: PROVRUST_04697
symbol: KdpD
gene_biotype: protein_coding
description:
  ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: plu:plu1417 0. kdpD; sensor protein (histidine kinase) K07646; Psort location: CytoplasmicMembrane, score: 9.99.


ensembl_gene_id: PROVRUST_04698
symbol: KdpE
gene_biotype: protein_coding
description:
  Response regulator receiver domain protein; KEGG: eci:UTI89_C0698 3.8e-84 kdpE; transcriptional regulatory protein KdpE K07667; Psort location: Cytoplasmic, score: 9.97.


ensembl_gene_id: PROVRUST_04702
symbol: glnS
gene_biotype: protein_coding
description:
  glutamine--tRNA ligase; KEGG: plu:plu1319 4.2e-275 glnS; glutaminyl-tRNA synthetase precursor (glutamine--tRNA ligase) K01886; Psort location: Cytoplasmic, score: 9.97.


ensembl_gene_id: PROVRUST_04705
symbol: nagE
gene_biotype: protein_coding
description:
  KEGG: ypn:YPN_1114 5.8e-262 PTS system, N-acetylglucosamine-specific IIABC component K02802:K02803:K02804; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_04706
symbol: nagB
gene_biotype: protein_coding
description:
  Glucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.


ensembl_gene_id: PROVRUST_04707
symbol: nagA
gene_biotype: protein_coding
description:
  KEGG: plu:plu1316 2.1e-147 nagA; N-acetylglucosamine-6-phosphate deacetylase (GLCNAC 6-P deacetylase) K01443.


ensembl_gene_id: PROVRUST_04708
symbol: Mlc_1
gene_biotype: protein_coding
description:
  ROK family protein; KEGG: eci:UTI89_C0670 2.4e-153 nagC; transcriptional repressor of nag (N-acetylglucosamine) operon K02565; Psort location: Cytoplasmic, score: 9.97.


ensembl_gene_id: PROVRUST_04715
symbol: dctA
gene_biotype: protein_coding
description:
  Putative C4-dicarboxylate transporter DctA; Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate across the membrane. Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: PROVRUST_04716
symbol: UbiF_1
gene_biotype: protein_coding
description:
  Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; KEGG: plu:plu1313 8.3e-144 ubiF; 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase UbiF K03184.


ensembl_gene_id: PROVRUST_04717
symbol: miaB
gene_biotype: protein_coding
description:
  tRNA-i(6)A37 thiotransferase enzyme MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.


ensembl_gene_id: PROVRUST_04718
symbol: YbeZ
gene_biotype: protein_coding
description:
  PhoH family protein; KEGG: reh:H16_A0527 3.2e-87 phoH; phosphate starvation-inducible protein PhoH,predicted ATPase; Psort location: Cytoplasmic, score: 9.97.


ensembl_gene_id: PROVRUST_04719
symbol: ybeY
gene_biotype: protein_coding
description:
  Translation metalloprotein YbeY; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.


ensembl_gene_id: PROVRUST_04720
symbol: CorC
gene_biotype: protein_coding
description:
  CBS domain protein; KEGG: eci:UTI89_C0656 3.9e-130 ybeX; putative transport protein K06189; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_04721
symbol: lnt
gene_biotype: protein_coding
description:
  Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily.


ensembl_gene_id: PROVRUST_04727
symbol: DsbD
gene_biotype: protein_coding
description:
  Hypothetical protein; KEGG: xcc:XCC0519 8.7e-62 dsbD; c-type cytochrome biogenesis protein K04084; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_04729
symbol: GltI
gene_biotype: protein_coding
description:
  KEGG: bur:Bcep18194_A4762 1.7e-19 ABC amino acid transporter, periplasmic ligand binding protein K01713; Psort location: Periplasmic, score: 9.44.


ensembl_gene_id: PROVRUST_04730
symbol: GltK_3
gene_biotype: protein_coding
description:
  KEGG: eca:ECA0855 8.0e-20 ABC transporter permease protein K02028; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_04731
symbol: gltK
gene_biotype: protein_coding
description:
  Glutamate/aspartate transport system permease protein GltK; KEGG: ret:RHE_PF00254 4.2e-26 glnP, glnQ; glutamine ABC transporter, ATP-binding protein K02028; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_04732
symbol: ArtM_1
gene_biotype: protein_coding
description:
  ABC transporter, ATP-binding protein; KEGG: plu:plu1304 1.2e-112 gltL; glutamate/aspartate transport ATP-binding protein GltL K02028; Psort location: Cytoplasmic, score: 9.12.


ensembl_gene_id: PROVRUST_04733
symbol: leuS
gene_biotype: protein_coding
description:
  leucine--tRNA ligase; KEGG: plu:plu1303 0. leuS; leucine-tRNA synthetase (leucine--tRNA ligase) (LEURS) K01869; Psort location: Cytoplasmic, score: 9.26; Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: PROVRUST_04734
symbol: lptE
gene_biotype: protein_coding
description:
  Rare lipoprotein B family protein; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.


ensembl_gene_id: PROVRUST_04736
symbol: nadD
gene_biotype: protein_coding
description:
  Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).


ensembl_gene_id: PROVRUST_04738
symbol: rsfS
gene_biotype: protein_coding
description:
  Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.


ensembl_gene_id: PROVRUST_04739
symbol: rlmH
gene_biotype: protein_coding
description:
  rRNA large subunit m3Psi methyltransferase RlmH; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family.


ensembl_gene_id: PROVRUST_04740
symbol: mrdA
gene_biotype: protein_coding
description:
  Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.


ensembl_gene_id: PROVRUST_04741
symbol: mrdB
gene_biotype: protein_coding
description:
  Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.


ensembl_gene_id: PROVRUST_04742
symbol: rlpA
gene_biotype: protein_coding
description:
  Sporulation and cell division repeat protein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.


ensembl_gene_id: PROVRUST_04743
symbol: DacA
gene_biotype: protein_coding
description:
  Serine-type D-Ala-D-Ala carboxypeptidase; KEGG: yps:YPTB1094 1.2e-165 dacA; putative penicillin-binding protein 5 K07258; Psort location: CytoplasmicMembrane, score: 8.02; Belongs to the peptidase S11 family.


ensembl_gene_id: PROVRUST_04745
symbol: lipB
gene_biotype: protein_coding
description:
  Lipoyl(octanoyl) transferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.


ensembl_gene_id: PROVRUST_04746
symbol: lipA
gene_biotype: protein_coding
description:
  Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.


ensembl_gene_id: PROVRUST_04748
symbol: Ogt
gene_biotype: protein_coding
description:
  6-O-methylguanine DNA methyltransferase, DNA binding domain protein; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.


ensembl_gene_id: PROVRUST_04751
symbol: NrdE
gene_biotype: protein_coding
description:
  Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.


ensembl_gene_id: PROVRUST_04752
symbol: NrdF2
gene_biotype: protein_coding
description:
  Ribonucleoside-diphosphate reductase, beta subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.


ensembl_gene_id: PROVRUST_04753
symbol: YnfM_1
gene_biotype: protein_coding
description:
  Transporter, major facilitator family protein; KEGG: shn:Shewana3_1692 1.4e-09 Xaa-His dipeptidase K01270; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_04756
symbol: emrB
gene_biotype: protein_coding
description:
  Multidrug resistance protein B; KEGG: sgl:SG1466 6.6e-09 dethiobiotin synthase K01935; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the major facilitator superfamily.


ensembl_gene_id: PROVRUST_04757
symbol: RlmB_1
gene_biotype: protein_coding
description:
  RNA methyltransferase, TrmH family; KEGG: plu:plu1274 1.3e-129 unnamed protein product; highly similar to putative tRNA/rRNA methyltransferase YfiF Escherichia coli K03214; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.


ensembl_gene_id: PROVRUST_04760
symbol: EFB74260.1
gene_biotype: protein_coding
description:
  CoA binding domain protein; KEGG: eci:UTI89_C2907 0. yfiQ; hypothetical protein YfiQ K09181; Psort location: OuterMembrane, score: 9.49.


ensembl_gene_id: PROVRUST_04761
symbol: PssA
gene_biotype: protein_coding
description:
  Phospholipase D domain protein; KEGG: plu:plu1271 1.5e-183 pssA; CDP-diacylglycerol--serine O-phosphatidyltransferase (phosphatidylserine synthase) K00998.


ensembl_gene_id: PROVRUST_04779
symbol: sotB
gene_biotype: protein_coding
description:
  Sugar efflux transporter; Involved in the efflux of sugars. The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites; Belongs to the major facilitator superfamily. SotB (TC 2.A.1.2) family.


ensembl_gene_id: PROVRUST_04780
symbol: EmrE_1
gene_biotype: protein_coding
description:
  Multidrug resistance protein, SMR family; KEGG: sus:Acid_0119 0.0097 proton-translocating NADH-quinone oxidoreductase, chain M K05903; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_04782
symbol: dsbB
gene_biotype: protein_coding
description:
  Disulfide bond formation protein DsbB; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family.


ensembl_gene_id: PROVRUST_04783
symbol: nhaB
gene_biotype: protein_coding
description:
  Na+/H+ antiporter NhaB; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.


ensembl_gene_id: PROVRUST_04784
symbol: fadR
gene_biotype: protein_coding
description:
  Fatty acid metabolism transcriptional regulator FadR; Multifunctional regulator of fatty acid metabolism.


ensembl_gene_id: PROVRUST_04787
symbol: alr
gene_biotype: protein_coding
description:
  Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.


ensembl_gene_id: PROVRUST_04789
symbol: YeaD
gene_biotype: protein_coding
description:
  Aldose 1-epimerase; KEGG: tbd:Tbd_2730 4.6e-35 dihydroxy-acid dehydratase K01687; Psort location: Cytoplasmic, score: 8.96; Belongs to the glucose-6-phosphate 1-epimerase family.


ensembl_gene_id: PROVRUST_04790
symbol: gap
gene_biotype: protein_coding
description:
  Glyceraldehyde-3-phosphate dehydrogenase, type I; KEGG: plu:plu2558 6.4e-169 gapA; glyceraldehyde-3-phosphate dehydrogenase A (GAPDH-A) K00134; Psort location: Cytoplasmic, score: 9.97.


ensembl_gene_id: PROVRUST_04791
symbol: msrB
gene_biotype: protein_coding
description:
  methionine-R-sulfoxide reductase; KEGG: plu:plu2557 1.6e-53 msrB; peptide methionine sulfoxide reductase MsrB K07305; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_04793
symbol: EFB73522.1
gene_biotype: protein_coding
description:
  Isochorismatase family protein; KEGG: plu:plu2555 1.2e-71 pncA; pyrazinamidase/nicotinamidase [includes: pyrazinamidase (PZASE); nicotinamidase (nicotine deamidase)] K01440:K08281.


ensembl_gene_id: PROVRUST_04794
symbol: AnsA
gene_biotype: protein_coding
description:
  L-asparaginase, type I; KEGG: plu:plu2554 5.4e-156 ansA; L-asparaginase I (L-asparagine amidohydrolase I) (L-asnase I) K01424; Psort location: Cytoplasmic, score: 9.97.


ensembl_gene_id: PROVRUST_04795
symbol: sppA
gene_biotype: protein_coding
description:
  Signal peptide peptidase SppA, 67K type; KEGG: plu:plu2553 1.2e-213 sppA; protease IV (endopeptidase IV) (signal peptide peptidase) K04773.


ensembl_gene_id: PROVRUST_04796
symbol: YdjA
gene_biotype: protein_coding
description:
  Nitroreductase family protein; KEGG: sbo:SBO_1322 6.8e-62 ydjA; hypothetical protein; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_04798
symbol: topB
gene_biotype: protein_coding
description:
  DNA topoisomerase; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA superc [...]


ensembl_gene_id: PROVRUST_04799
symbol: xth
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease III; KEGG: yps:YPTB2094 3.7e-118 xthA, xth; exodeoxyribonuclease III K01142; Psort location: Cytoplasmic, score: 9.97.


ensembl_gene_id: PROVRUST_04801
symbol: AbgR
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; Psort location: Cytoplasmic, score: 8.96; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: PROVRUST_04803
symbol: purU
gene_biotype: protein_coding
description:
  Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).


ensembl_gene_id: PROVRUST_04804
symbol: rssB-2
gene_biotype: protein_coding
description:
  Response regulator receiver domain protein; Regulates the turnover of the sigma S factor (RpoS) by promoting its proteolysis in exponentially growing cells. Acts by binding and delivering RpoS to the ClpXP protease. RssB is not co- degraded with RpoS, but is released from the complex and can initiate a new cycle of RpoS recognition and degradation.


ensembl_gene_id: PROVRUST_04806
symbol: galU
gene_biotype: protein_coding
description:
  KEGG: plu:plu2501 2.5e-128 galU; UTP--glucose-1-phosphate uridylyltransferase (UDP-glucose pyrophosphorylase) (UDPGP) K00963; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_04810
symbol: AdhE_1
gene_biotype: protein_coding
description:
  Aldehyde dehydrogenase (NAD) family protein; KEGG: yps:YPTB2103 0. adhE, ana; aldehyde-alcohol dehydrogenase K00001:K04072; Psort location: Cytoplasmic, score: 9.26; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.


ensembl_gene_id: PROVRUST_04813
symbol: OppA_3
gene_biotype: protein_coding
description:
  ABC transporter, substrate-binding protein, family 5; KEGG: shn:Shewana3_2650 2.3e-21 acetate kinase K00925; Psort location: Periplasmic, score: 9.44.


ensembl_gene_id: PROVRUST_04814
symbol: OppA_1
gene_biotype: protein_coding
description:
  ABC transporter, substrate-binding protein, family 5; KEGG: shn:Shewana3_2650 1.0e-26 acetate kinase K00925; Psort location: Periplasmic, score: 10.00.


ensembl_gene_id: PROVRUST_04815
symbol: oppB
gene_biotype: protein_coding
description:
  KEGG: rha:RHA1_ro09047 2.8e-40 ABC peptide transporter, permease component K02033; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_04816
symbol: oppC
gene_biotype: protein_coding
description:
  KEGG: baa:BA_0884 0.00046 binding-protein-dependent transport systems inner membrane component K00294; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_04817
symbol: GsiA_6
gene_biotype: protein_coding
description:
  ABC transporter, ATP-binding protein; KEGG: bur:Bcep18194_B0118 3.3e-94 oligopeptide/dipeptide ABC transporter, ATPase subunit K02031; Psort location: CytoplasmicMembrane, score: 9.98.


ensembl_gene_id: PROVRUST_04818
symbol: GsiA_5
gene_biotype: protein_coding
description:
  ABC transporter, ATP-binding protein; KEGG: bur:Bcep18194_B0119 1.2e-94 oligopeptide/dipeptide ABC transporter, ATPase subunit K02032; Psort location: CytoplasmicMembrane, score: 9.59.


ensembl_gene_id: PROVRUST_04820
symbol: clsA
gene_biotype: protein_coding
description:
  Cardiolipin synthetase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.


ensembl_gene_id: PROVRUST_04822
symbol: TonB_2
gene_biotype: protein_coding
description:
  TonB-dependent receptor; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.


ensembl_gene_id: PROVRUST_04823
symbol: EFB73551.1
gene_biotype: protein_coding
description:
  Thioesterase family protein; KEGG: plu:plu2484 9.0e-60 unnamed protein product; highly similar to putative acyl-CoA thioester hydrolase YciA (P14 protein) of Escherichia coli K01076.


ensembl_gene_id: PROVRUST_04824
symbol: ispZ
gene_biotype: protein_coding
description:
  Intracellular septation protein A; Involved in cell division; probably involved in intracellular septation; Belongs to the YciB family.


ensembl_gene_id: PROVRUST_04825
symbol: sulP
gene_biotype: protein_coding
description:
  Sulfate permease; KEGG: eci:UTI89_C1400 6.2e-24 ychM; putative sulfate transporter YchM K03321; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_04828
symbol: trpA
gene_biotype: protein_coding
description:
  Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.


ensembl_gene_id: PROVRUST_04829
symbol: trpB
gene_biotype: protein_coding
description:
  Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.


ensembl_gene_id: PROVRUST_04830
symbol: trpC
gene_biotype: protein_coding
description:
  Indole-3-glycerol phosphate synthase; KEGG: plu:plu2465 1.6e-156 trpC; tryptophan biosynthesis protein TrpCF [includes: indole-3-glycerol phosphate synthase (IGPS); N-(5'-phospho-ribosyl)anthrnilate isomerase (PRAI)] K01609:K01817.


ensembl_gene_id: PROVRUST_04831
symbol: trpD
gene_biotype: protein_coding
description:
  Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).


ensembl_gene_id: PROVRUST_04832
symbol: TrpG_2
gene_biotype: protein_coding
description:
  Glutamine amidotransferase, class I; KEGG: ecp:ECP_1311 1.1e-72 anthranilate synthase component II K00766:K01658.


ensembl_gene_id: PROVRUST_04833
symbol: trpE
gene_biotype: protein_coding
description:
  KEGG: plu:plu2462 5.0e-169 trpE; anthranilate synthase component I K01657; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_04834
symbol: EFB73562.1
gene_biotype: protein_coding
description:
  PHP domain protein; KEGG: reh:H16_A1200 1.6e-39 predicted metal-dependent phosphoesterase (PHP family).


ensembl_gene_id: PROVRUST_04835
symbol: YciO
gene_biotype: protein_coding
description:
  Sua5/YciO/YrdC/YwlC family protein; Psort location: Cytoplasmic, score: 8.96; Belongs to the SUA5 family.


ensembl_gene_id: PROVRUST_04836
symbol: RluB
gene_biotype: protein_coding
description:
  Pseudouridylate synthase; KEGG: plu:plu2452 1.8e-132 unnamed protein product; highly similar to probable pseudouridylate synthase YciL of Escherichia coli K06178; Psort location: Cytoplasmic, score: 8.96; Belongs to the pseudouridine synthase RsuA family.


ensembl_gene_id: PROVRUST_04838
symbol: cobO
gene_biotype: protein_coding
description:
  cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.


ensembl_gene_id: PROVRUST_04839
symbol: YciK
gene_biotype: protein_coding
description:
  Oxidoreductase, short chain dehydrogenase/reductase family protein; KEGG: ecc:c1736 4.6e-88 yciK; short chain dehydrogenase; Psort location: Cytoplasmic, score: 9.26.


ensembl_gene_id: PROVRUST_04840
symbol: SohB
gene_biotype: protein_coding
description:
  Putative signal peptide peptidase SppA, 36K type; KEGG: plu:plu2439 1.9e-137 sohB; possible protease SohB K04774.


ensembl_gene_id: PROVRUST_04842
symbol: topA
gene_biotype: protein_coding
description:
  DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]


ensembl_gene_id: PROVRUST_04843
symbol: sodC
gene_biotype: protein_coding
description:
  Copper/zinc superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family.


ensembl_gene_id: PROVRUST_04844
symbol: PepO_2
gene_biotype: protein_coding
description:
  Peptidase family M13; KEGG: mmr:Mmar10_0473 1.1e-159 endothelin-converting enzyme 1 K01415; Psort location: Cytoplasmic, score: 9.26.


ensembl_gene_id: PROVRUST_04845
symbol: cysB
gene_biotype: protein_coding
description:
  KEGG: shn:Shewana3_3435 1.1e-12 transcriptional regulator, LysR family K06022; Psort location: Cytoplasmic, score: 9.97; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: PROVRUST_04848
symbol: hemB
gene_biotype: protein_coding
description:
  Porphobilinogen synthase; KEGG: pfl:PFL_2290 1.3e-131 hemB; delta-aminolevulinic acid dehydratase K01698; Psort location: Cytoplasmic, score: 8.96; Belongs to the ALAD family.


ensembl_gene_id: PROVRUST_04849
symbol: ribA
gene_biotype: protein_coding
description:
  GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.


ensembl_gene_id: PROVRUST_04850
symbol: PgpB
gene_biotype: protein_coding
description:
  PAP2 family protein; KEGG: ypa:YPA_1583 1.2e-48 phosphatidylglycerophosphatase B K01096; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_04851
symbol: lapA
gene_biotype: protein_coding
description:
  Hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family.


ensembl_gene_id: PROVRUST_04852
symbol: lapB
gene_biotype: protein_coding
description:
  Tetratricopeptide repeat protein; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane; Belongs to the LapB family.


ensembl_gene_id: PROVRUST_04853
symbol: pyrF
gene_biotype: protein_coding
description:
  Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.


ensembl_gene_id: PROVRUST_04855
symbol: EFB73583.1
gene_biotype: protein_coding
description:
  Putative Osmotically-inducible lipoprotein B; KEGG: ttj:TTHA1277 0.0072 V-type ATP synthase, subunit K K02124.


ensembl_gene_id: PROVRUST_04856
symbol: rnb
gene_biotype: protein_coding
description:
  Exoribonuclease II; Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction.


ensembl_gene_id: PROVRUST_04857
symbol: nth
gene_biotype: protein_coding
description:
  Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.


ensembl_gene_id: PROVRUST_04858
symbol: rnfE
gene_biotype: protein_coding
description:
  Electron transport complex, RnfABCDGE type, E subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.


ensembl_gene_id: PROVRUST_04859
symbol: rnfG
gene_biotype: protein_coding
description:
  Electron transport complex, RnfABCDGE type, G subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the RnfG family.


ensembl_gene_id: PROVRUST_04860
symbol: rnfD
gene_biotype: protein_coding
description:
  Electron transport complex protein RnfD; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the NqrB/RnfD family.


ensembl_gene_id: PROVRUST_04861
symbol: rnfC
gene_biotype: protein_coding
description:
  Electron transport complex, RnfABCDGE type, C subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.


ensembl_gene_id: PROVRUST_04862
symbol: rnfB
gene_biotype: protein_coding
description:
  Electron transport complex, RnfABCDGE type, B subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.


ensembl_gene_id: PROVRUST_04863
symbol: rnfA
gene_biotype: protein_coding
description:
  Electron transport complex, RnfABCDGE type, A subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.


ensembl_gene_id: PROVRUST_04865
symbol: YdgJ
gene_biotype: protein_coding
description:
  Oxidoreductase, NAD-binding domain protein; KEGG: eci:UTI89_C1812 2.9e-102 ydgJ; hypothetical oxidoreductase YdgJ.


ensembl_gene_id: PROVRUST_04867
symbol: add
gene_biotype: protein_coding
description:
  Adenosine deaminase; KEGG: aha:AHA_0273 5.3e-126 add-1; adenosine deaminase K01488; Psort location: Cytoplasmic, score: 8.96; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.


ensembl_gene_id: PROVRUST_04869
symbol: manA
gene_biotype: protein_coding
description:
  KEGG: plu:plu2360 2.4e-137 manA; mannose-6-phosphate isomerase (phosphomannose isomerase) (phosphohexomutase) (PMI) K01809.


ensembl_gene_id: PROVRUST_04870
symbol: fumC
gene_biotype: protein_coding
description:
  Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.


ensembl_gene_id: PROVRUST_04872
symbol: YnfM_2
gene_biotype: protein_coding
description:
  Transporter, major facilitator family protein; KEGG: shn:Shewana3_1692 1.1e-43 Xaa-His dipeptidase K01270; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_04873
symbol: BenM
gene_biotype: protein_coding
description:
  LysR substrate binding domain protein; KEGG: shn:Shewana3_3435 1.5e-25 transcriptional regulator, LysR family K06022; Psort location: Cytoplasmic, score: 9.26; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: PROVRUST_04874
symbol: Mlc_2
gene_biotype: protein_coding
description:
  ROK family protein; KEGG: eci:UTI89_C1781 1.7e-72 mlc; putative NAGC-like transcriptional regulator K00845.


ensembl_gene_id: PROVRUST_04878
symbol: YdfG
gene_biotype: protein_coding
description:
  Oxidoreductase, short chain dehydrogenase/reductase family protein; KEGG: plu:plu2233 1.4e-95 unnamed protein product; similar to probable oxidoreductase YdfG of Escherichia coli; Psort location: Cytoplasmic, score: 9.26; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: PROVRUST_04879
symbol: SseJ
gene_biotype: protein_coding
description:
  GDSL-like protein; KEGG: aha:AHA_3791 5.6e-26 phosphatidylcholine-sterol acyltransferase K00650; Psort location: Extracellular, score: 9.71.


ensembl_gene_id: PROVRUST_04884
symbol: EFB73612.1
gene_biotype: protein_coding
description:
  Acetyltransferase, GNAT family; KEGG: efa:EF2473 1.8e-06 ribosomal-protein-alanine acetyltransferase, putative K03789; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_04885
symbol: CueR_1
gene_biotype: protein_coding
description:
  Transcriptional regulator, MerR family; KEGG: syn:sll0794 8.3e-09 corR, merR, cobH, cbiC; cobalt-dependent transcriptional regulator (MerR (mercuric resistance operon regulatory protein)-like domain in N-terminal half), precorrin isomerase, Precorrin-8X methylmutase (in C-terminal half) K01833; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_04886
symbol: EFB73614.1
gene_biotype: protein_coding
description:
  Transporter, major facilitator family protein; KEGG: shn:Shewana3_1692 0.00030 Xaa-His dipeptidase K01270; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_04888
symbol: Gsp_1
gene_biotype: protein_coding
description:
  CHAP domain protein; KEGG: spt:SPA3007 1.9e-240 gsp; glutathionylspermidine synthetase/amidase K01460:K01917; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_04889
symbol: EFB73617.1
gene_biotype: protein_coding
description:
  Hypothetical protein; KEGG: pfu:PF0176 0.0092 V-type H+-transporting ATPase subunit E K02121; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_04890
symbol: selU
gene_biotype: protein_coding
description:
  tRNA 2-selenouridine synthase; Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2- selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.


ensembl_gene_id: PROVRUST_04893
symbol: LtaE
gene_biotype: protein_coding
description:
  Beta-eliminating lyase; KEGG: cac:CAC3420 2.7e-83 low specificity L-threonine aldolase K01620; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_04894
symbol: yedA
gene_biotype: protein_coding
description:
  Carboxylate/Amino Acid/Amine Transporter; KEGG: pae:PA1977 1.2e-05 sensor protein GLPS; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_04899
symbol: EFB73627.1
gene_biotype: protein_coding
description:
  ATPase family associated with various cellular activities (AAA); KEGG: eci:UTI89_C2392 3.4e-83 yehL; hypothetical protein YehL K01157; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_04902
symbol: Psdht
gene_biotype: protein_coding
description:
  Pyridoxal-phosphate dependent protein; KEGG: eca:ECA2040 1.1e-127 serine/threonine dehydratase K01754.


ensembl_gene_id: PROVRUST_04905
symbol: EFB73633.1
gene_biotype: protein_coding
description:
  4Fe-4S binding domain protein; KEGG: mth:MTH1554 1.0e-07 tungsten formylmethanofuran dehydrogenase, subunit F K00205; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_04906
symbol: YqhD
gene_biotype: protein_coding
description:
  KEGG: abo:ABO_2419 1.1e-143 alcohol dehydrogenase, NADH-dependent, putative K00001; Psort location: Cytoplasmic, score: 9.26.


ensembl_gene_id: PROVRUST_04909
symbol: DmlR_5
gene_biotype: protein_coding
description:
  LysR substrate binding domain protein; KEGG: shn:Shewana3_3435 2.2e-14 transcriptional regulator, LysR family K06022; Psort location: Cytoplasmic, score: 9.26; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: PROVRUST_04911
symbol: EFB73639.1
gene_biotype: protein_coding
description:
  Acetyltransferase, GNAT family; KEGG: fnu:FN1294 1.1e-22 ribosomal-protein-alanine acetyltransferase K00676.


ensembl_gene_id: PROVRUST_04913
symbol: DcyD
gene_biotype: protein_coding
description:
  Pyridoxal phosphate-dependent enzyme, D-cysteine desulfhydrase family; KEGG: ype:YPO1845 1.3e-104 yedO; 1-aminocyclopropane-1-carboxylate deaminase K05396; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_04914
symbol: EFB73642.1
gene_biotype: protein_coding
description:
  Putative membrane protein; KEGG: pae:PA1977 3.2e-07 sensor protein GLPS; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_04915
symbol: GltC_1
gene_biotype: protein_coding
description:
  LysR substrate binding domain protein; KEGG: shn:Shewana3_3435 3.8e-20 transcriptional regulator, LysR family K06022; Psort location: Cytoplasmic, score: 9.26; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: PROVRUST_04919
symbol: EFB73647.1
gene_biotype: protein_coding
description:
  Acetyltransferase, GNAT family; KEGG: vch:VC0657 2.5e-09 ribosomal-protein-alanine acetyltransferase K03789.


ensembl_gene_id: PROVRUST_04920
symbol: ddl
gene_biotype: protein_coding
description:
  D-ala D-ala ligase N-terminal domain protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.


ensembl_gene_id: PROVRUST_04921
symbol: GcvA_2
gene_biotype: protein_coding
description:
  LysR substrate binding domain protein; KEGG: shn:Shewana3_3435 0.00010 transcriptional regulator, LysR family K06022; Psort location: Cytoplasmic, score: 9.26; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: PROVRUST_04923
symbol: EFB73651.1
gene_biotype: protein_coding
description:
  Efflux transporter, RND family, MFP subunit; Psort location: CytoplasmicMembrane, score: 8.02; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: PROVRUST_04924
symbol: MexB
gene_biotype: protein_coding
description:
  RND transporter, HAE1/HME family, permease protein; KEGG: eci:UTI89_C2351 1.8e-100 yegO; hypothetical protein YegO K07789; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: PROVRUST_04929
symbol: DmlR_4
gene_biotype: protein_coding
description:
  LysR substrate binding domain protein; Psort location: Cytoplasmic, score: 9.26; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: PROVRUST_04930
symbol: accA
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.


ensembl_gene_id: PROVRUST_04932
symbol: amn
gene_biotype: protein_coding
description:
  AMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.


ensembl_gene_id: PROVRUST_04935
symbol: GabR
gene_biotype: protein_coding
description:
  Transcriptional regulator, GntR family; KEGG: ava:Ava_1933 8.8e-85 regulatory protein GntR, HTH K00375; Psort location: Cytoplasmic, score: 9.26.


ensembl_gene_id: PROVRUST_04937
symbol: EFB73665.1
gene_biotype: protein_coding
description:
  Hypothetical protein; KEGG: hsa:54575 0.0078 UGT1A10; UDP glucuronosyltransferase 1 family, polypeptide A10 K00699.


ensembl_gene_id: PROVRUST_04938
symbol: XecA1
gene_biotype: protein_coding
description:
  Methionine synthase, vitamin-B12 independent; KEGG: eca:ECA3126 1.3e-170 metE; 5-methyltetrahydropteroyltriglutamate- homocystein e methyltransferase K00549; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_04943
symbol: EFB73671.1
gene_biotype: protein_coding
description:
  Hypothetical protein; KEGG: ddi:DDB0231453 0.0011 alg10; dolichyl-phosphate-glucose alpha-1,2-glucosyltransferase K03850; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_04951
symbol: EFB73679.1
gene_biotype: protein_coding
description:
  RelA/SpoT domain protein; KEGG: fnu:FN0926 9.0e-44 GTP pyrophosphokinase K00951; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_04961
symbol: EFB73689.1
gene_biotype: protein_coding
description:
  Bacteriophage lysis protein; KEGG: eco:b1362 0.00038 rzpR; Rac prophage; predicted defective peptidase K01423.


ensembl_gene_id: PROVRUST_04962
symbol: EFB73690.1
gene_biotype: protein_coding
description:
  Phage lysozyme; KEGG: ecj:JW1546 1.4e-54 ydfQ; predicted lysozyme K01238; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_04972
symbol: EFB73700.1
gene_biotype: protein_coding
description:
  Methyltransferase domain protein; KEGG: ddi:DDB0215313 0.00043 hypothetical protein K00591; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_04983
symbol: ahpF
gene_biotype: protein_coding
description:
  KEGG: ecp:ECP_0639 1.7e-216 alkyl hydroperoxide reductase subunit F K03387; Psort location: Cytoplasmic, score: 9.97.


ensembl_gene_id: PROVRUST_04984
symbol: ahpC
gene_biotype: protein_coding
description:
  Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.


ensembl_gene_id: PROVRUST_04985
symbol: YhhJ_1
gene_biotype: protein_coding
description:
  ABC-2 type transporter; KEGG: fal:FRAAL1796 2.2e-07 putative ABC transporter ATP-binding subunit; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_04986
symbol: YbhF_2
gene_biotype: protein_coding
description:
  ABC transporter, ATP-binding protein; KEGG: rru:Rru_A1792 1.1e-79 ABC transporter component K01990; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_04987
symbol: MacA_5
gene_biotype: protein_coding
description:
  Auxiliary transport protein, membrane fusion protein (MFP) family protein; KEGG: eci:UTI89_C0735 0.00014 tolA; membrane spanning protein TolA K03646; Psort location: CytoplasmicMembrane, score: 8.02.


ensembl_gene_id: PROVRUST_04988
symbol: YheS_4
gene_biotype: protein_coding
description:
  KEGG: bur:Bcep18194_C7259 4.9e-139 ABC transporter, duplicated ATPase domains; Psort location: CytoplasmicMembrane, score: 9.82.


ensembl_gene_id: PROVRUST_04993
symbol: PpsC
gene_biotype: protein_coding
description:
  NAD(P)H quinone oxidoreductase, PIG3 family; KEGG: bur:Bcep18194_B3044 1.3e-83 zinc-containing alcohol dehydrogenase superfamily K00344.


ensembl_gene_id: PROVRUST_04994
symbol: fnr
gene_biotype: protein_coding
description:
  Fumarate and nitrate reduction regulatory protein; KEGG: eci:UTI89_C3860 1.8e-09 crp; CRP-cAMP transcriptional dual regulator K00924; Psort location: Cytoplasmic, score: 9.97.


ensembl_gene_id: PROVRUST_04996
symbol: pntB
gene_biotype: protein_coding
description:
  NAD(P) transhydrogenase subunit beta; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.


ensembl_gene_id: PROVRUST_04997
symbol: EFB73725.1
gene_biotype: protein_coding
description:
  Hypothetical protein; KEGG: ypa:YPA_1652 3.5e-49 NAD(P) transhydrogenase alpha subunit K00324; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_04998
symbol: pntA
gene_biotype: protein_coding
description:
  KEGG: eca:ECA2204 2.8e-152 pntA; pyridine nucleotide transhydrogenase subunit-alpha K00324; Psort location: CytoplasmicMembrane, score: 9.82.


ensembl_gene_id: PROVRUST_05000
symbol: YdgI_2
gene_biotype: protein_coding
description:
  Transporter, basic amino acid/polyamine antiporter (APA) family; KEGG: eci:UTI89_C0120 1.2e-10 aroP; aromatic amino acid transport protein AroP K03293; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_05002
symbol: azoR
gene_biotype: protein_coding
description:
  NAD(P)H dehydrogenase (quinone); Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity; Belongs to the azoreductase type 1 family.


ensembl_gene_id: PROVRUST_05006
symbol: pdxB
gene_biotype: protein_coding
description:
  KEGG: plu:plu2145 9.7e-150 ldhA; D-lactate dehydrogenase (D-LDH) K03778; Psort location: Cytoplasmic, score: 9.97; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: PROVRUST_05008
symbol: grxB
gene_biotype: protein_coding
description:
  Glutaredoxin, GrxB family; KEGG: eci:UTI89_C1189 7.3e-42 grxB; glutaredoxin 2 K03675; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_05009
symbol: EFB73737.1
gene_biotype: protein_coding
description:
  DNA-binding helix-turn-helix protein; KEGG: mmo:MMOB3450 0.00015 dam; adenine-specific DNA methyltransferase K06223; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_05015
symbol: YcgM
gene_biotype: protein_coding
description:
  FAH family protein; KEGG: chu:CHU_1891 3.1e-41 ycgM; 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase, fumarylacetoacetate hydrolase family K01828.


ensembl_gene_id: PROVRUST_05016
symbol: MltB
gene_biotype: protein_coding
description:
  KEGG: vfi:VF1702 1.1e-75 membrane-bound lytic murein transglycosylase B K01238; Psort location: CytoplasmicMembrane, score: 8.02.


ensembl_gene_id: PROVRUST_05018
symbol: minC
gene_biotype: protein_coding
description:
  Septum site-determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family.


ensembl_gene_id: PROVRUST_05019
symbol: minD
gene_biotype: protein_coding
description:
  Septum site-determining protein MinD; KEGG: eci:UTI89_C1360 3.3e-124 minD; cell division inhibitor, membrane ATPase MinD K03609; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_05020
symbol: minE
gene_biotype: protein_coding
description:
  Cell division topological specificity factor MinE; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.


ensembl_gene_id: PROVRUST_05026
symbol: rnd
gene_biotype: protein_coding
description:
  Ribonuclease D; Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides; Belongs to the RNase D family.


ensembl_gene_id: PROVRUST_05027
symbol: FadD
gene_biotype: protein_coding
description:
  KEGG: plu:plu2134 2.7e-234 fadD; long-chain-fatty-acid--CoA ligase (long-chain acyl-CoA synthetase) K01897; Psort location: Cytoplasmic, score: 9.26.


ensembl_gene_id: PROVRUST_05037
symbol: PdxK
gene_biotype: protein_coding
description:
  Pyridoxal kinase; KEGG: sfl:SF2473 1.2e-64 pdxK; pyridoxal-pyridoxine-pyridoxamine kinase K00868; Belongs to the pyridoxine kinase family.


ensembl_gene_id: PROVRUST_05042
symbol: zwf
gene_biotype: protein_coding
description:
  Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.


ensembl_gene_id: PROVRUST_05043
symbol: YbbH_2
gene_biotype: protein_coding
description:
  Transcriptional regulator, RpiR family; KEGG: bxe:Bxe_A3454 1.5e-43 glucokinase K00845; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_05044
symbol: pyk
gene_biotype: protein_coding
description:
  Pyruvate kinase; KEGG: plu:plu2118 4.1e-222 pykA; pyruvate kinase II K00873; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_05050
symbol: msbB
gene_biotype: protein_coding
description:
  Lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase; Catalyzes the transfer of myristate from myristoyl-acyl carrier protein (ACP) to Kdo(2)-(lauroyl)-lipid IV(A) to form Kdo(2)- lipid A.


ensembl_gene_id: PROVRUST_05052
symbol: ZnuA
gene_biotype: protein_coding
description:
  Putative high-affinity zinc transporter periplasmic component; Psort location: Periplasmic, score: 9.44; Belongs to the bacterial solute-binding protein 9 family.


ensembl_gene_id: PROVRUST_05053
symbol: znuC
gene_biotype: protein_coding
description:
  High-affinity zinc transporter ATPase; Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family.


ensembl_gene_id: PROVRUST_05054
symbol: znuB
gene_biotype: protein_coding
description:
  High-affinity zinc transporter membrane component; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_05056
symbol: ruvB
gene_biotype: protein_coding
description:
  Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.


ensembl_gene_id: PROVRUST_05057
symbol: ruvA
gene_biotype: protein_coding
description:
  Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.


ensembl_gene_id: PROVRUST_05058
symbol: ruvC
gene_biotype: protein_coding
description:
  Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.


ensembl_gene_id: PROVRUST_05059
symbol: YebC
gene_biotype: protein_coding
description:
  DNA-binding regulatory protein, YebC/PmpR family; KEGG: eci:UTI89_C2068 2.1e-106 yebC; hypothetical protein K00975.


ensembl_gene_id: PROVRUST_05060
symbol: NudB
gene_biotype: protein_coding
description:
  Hydrolase, NUDIX family; KEGG: msu:MS0709 8.1e-43 mutT; NTP pyrophosphohydrolases including oxidative damage repair enzymes K08310.


ensembl_gene_id: PROVRUST_05061
symbol: aspS
gene_biotype: protein_coding
description:
  aspartate--tRNA ligase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.


ensembl_gene_id: PROVRUST_05063
symbol: EFB73791.1
gene_biotype: protein_coding
description:
  KEGG: ftf:FTF0305 3.2e-09 MutT/NUDIX family protein K01529; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_05064
symbol: YecN
gene_biotype: protein_coding
description:
  Hypothetical protein; KEGG: mmu:66447 2.9e-06 Mgst3; microsomal glutathione S-transferase 3 K00799; Psort location: CytoplasmicMembrane, score: 9.46.


ensembl_gene_id: PROVRUST_05065
symbol: cmoA
gene_biotype: protein_coding
description:
  Putative methyltransferase; Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).


ensembl_gene_id: PROVRUST_05066
symbol: cmoB
gene_biotype: protein_coding
description:
  Putative methyltransferase; Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L- methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5- carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.


ensembl_gene_id: PROVRUST_05070
symbol: argS
gene_biotype: protein_coding
description:
  arginine--tRNA ligase; KEGG: plu:plu2092 1.8e-260 argS; arginyl-tRNA synthetase (arginine-tRNA ligase) K01887; Psort location: Cytoplasmic, score: 9.97.


ensembl_gene_id: PROVRUST_05073
symbol: amt
gene_biotype: protein_coding
description:
  Ammonium transporter; KEGG: ter:Tery_3993 8.0e-38 adenylate/guanylate cyclase K01769; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_05074
symbol: mviN
gene_biotype: protein_coding
description:
  Integral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.


ensembl_gene_id: PROVRUST_05075
symbol: EFB73803.1
gene_biotype: protein_coding
description:
  Acetyltransferase, GNAT family; KEGG: plu:plu2090 2.6e-78 rimJ; ribosomal-protein-alanine acetyltransferase (acetylating enzyme for N-terminal of ribosomal protein S5) K03790; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_05078
symbol: mdtH
gene_biotype: protein_coding
description:
  Transporter, major facilitator family protein; KEGG: dre:30298 0.00084 jak2b; Janus kinase 2b K04447; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_05083
symbol: YcdY
gene_biotype: protein_coding
description:
  Cytoplasmic chaperone TorD; KEGG: vfi:VFA0083 8.1e-11 ynfI; anaerobic dimethyl sulfoxide reductase chain YnfI K00397; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_05084
symbol: pdxB-2
gene_biotype: protein_coding
description:
  4-phosphoerythronate dehydrogenase; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively.


ensembl_gene_id: PROVRUST_05086
symbol: agcS
gene_biotype: protein_coding
description:
  Amino acid carrier protein; KEGG: hpa:HPAG1_0925 7.6e-63 D-alanine glycine permease K01613; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_05087
symbol: PuuC
gene_biotype: protein_coding
description:
  Aldehyde dehydrogenase (NAD) family protein; KEGG: pcr:Pcryo_1216 4.4e-193 aldehyde dehydrogenase (NAD+) K00128; Psort location: Cytoplasmic, score: 9.26.


ensembl_gene_id: PROVRUST_05088
symbol: dapA
gene_biotype: protein_coding
description:
  Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).


ensembl_gene_id: PROVRUST_05089
symbol: LhgO_1
gene_biotype: protein_coding
description:
  FAD dependent oxidoreductase; KEGG: pen:PSEEN4053 3.0e-84 D-amino acid dehydrogenase, small subunit family protein K00285.


ensembl_gene_id: PROVRUST_05090
symbol: EFB73817.1
gene_biotype: protein_coding
description:
  Proline racemase; KEGG: bur:Bcep18194_B1894 2.3e-100 proline racemase K01777; Belongs to the proline racemase family.


ensembl_gene_id: PROVRUST_05091
symbol: SoxS_2
gene_biotype: protein_coding
description:
  KEGG: bcz:BCZK3497 3.8e-10 adaA; transcriptional regulator, AraC family K00567; Psort location: Cytoplasmic, score: 9.26.


ensembl_gene_id: PROVRUST_05092
symbol: YnbA
gene_biotype: protein_coding
description:
  KEGG: ret:RHE_CH03135 2.3e-54 probable CDP-alcohol phosphatidyltransferase protein K00995; Psort location: CytoplasmicMembrane, score: 9.46.


ensembl_gene_id: PROVRUST_05093
symbol: YtpA
gene_biotype: protein_coding
description:
  Hydrolase, alpha/beta domain protein; KEGG: eci:UTI89_C1632 4.7e-189 ynbC; putative methylase K00599; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_05094
symbol: EFB73821.1
gene_biotype: protein_coding
description:
  Dual specificity phosphatase, catalytic domain protein; KEGG: eci:UTI89_C1633 1.4e-95 ynbD; putative enzyme YnbD K01104; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_05097
symbol: sulP-2
gene_biotype: protein_coding
description:
  Sulfate permease; KEGG: eci:UTI89_C1400 5.1e-199 ychM; putative sulfate transporter YchM K03321; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_05098
symbol: HcpC_2
gene_biotype: protein_coding
description:
  Sel1 repeat protein; KEGG: eci:UTI89_C1133 5.9e-17 hypothetical protein; Psort location: Extracellular, score: 9.71.


ensembl_gene_id: PROVRUST_05099
symbol: EFB73826.1
gene_biotype: protein_coding
description:
  Radical SAM protein, TIGR01212 family; KEGG: eci:UTI89_C3647 1.1e-111 yhcC; hypothetical protein; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_05100
symbol: kdsA
gene_biotype: protein_coding
description:
  3-deoxy-8-phosphooctulonate synthase; KEGG: eca:ECA2194 7.6e-134 kdsA; 2-dehydro-3-deoxyphosphooctonate aldolase K01627; Psort location: Cytoplasmic, score: 8.96; Belongs to the KdsA family.


ensembl_gene_id: PROVRUST_05102
symbol: prmC
gene_biotype: protein_coding
description:
  protein-(glutamine-N5) methyltransferase, release factor-specific; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.


ensembl_gene_id: PROVRUST_05103
symbol: prfA
gene_biotype: protein_coding
description:
  Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.


ensembl_gene_id: PROVRUST_05104
symbol: hemA
gene_biotype: protein_coding
description:
  glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).


ensembl_gene_id: PROVRUST_05105
symbol: lolB
gene_biotype: protein_coding
description:
  Outer membrane lipoprotein LolB; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.


ensembl_gene_id: PROVRUST_05106
symbol: ispE
gene_biotype: protein_coding
description:
  4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol; Belongs to the GHMP kinase family. IspE subfamily.


ensembl_gene_id: PROVRUST_05107
symbol: prs
gene_biotype: protein_coding
description:
  Ribose-phosphate diphosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.


ensembl_gene_id: PROVRUST_05109
symbol: pth
gene_biotype: protein_coding
description:
  aminoacyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.


ensembl_gene_id: PROVRUST_05110
symbol: ychF
gene_biotype: protein_coding
description:
  GTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.


ensembl_gene_id: PROVRUST_05111
symbol: EFB73838.1
gene_biotype: protein_coding
description:
  Putative xanthine dehydrogenase accessory factor; KEGG: bsu:BG13992 3.5e-17 pucA, yurF; xanthine dehydrogenase K00087; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_05112
symbol: EFB73839.1
gene_biotype: protein_coding
description:
  Hypothetical protein; KEGG: hma:pNG7236 2.3e-07 glmU; UDP-N-acetylglucosamine pyrophosphorylase K00972.


ensembl_gene_id: PROVRUST_05113
symbol: NdhM
gene_biotype: protein_coding
description:
  Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding domain protein; KEGG: bur:Bcep18194_B1541 0. aldehyde oxidase K00087.


ensembl_gene_id: PROVRUST_05114
symbol: HcrC
gene_biotype: protein_coding
description:
  2Fe-2S iron-sulfur cluster-binding domain protein; KEGG: bur:Bcep18194_B1542 5.2e-71 (2Fe-2S)-binding protein K04106; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_05120
symbol: YdcR
gene_biotype: protein_coding
description:
  Transcriptional regulator, GntR family; KEGG: eci:UTI89_C1658 5.8e-136 ydcR; hypothetical protein YdcR K00811; Psort location: Cytoplasmic, score: 9.26.


ensembl_gene_id: PROVRUST_05121
symbol: CydA_2
gene_biotype: protein_coding
description:
  Bacterial cytochrome ubiquinol oxidase; KEGG: plu:plu2043 2.7e-209 unnamed protein product; similar to quinol oxidase subunit I K00425; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_05122
symbol: EFB73849.1
gene_biotype: protein_coding
description:
  Cytochrome oxidase subunit II; KEGG: plu:plu2042 1.1e-52 unnamed protein product; similar to quinol oxidase subunit II K00426; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_05123
symbol: AppB
gene_biotype: protein_coding
description:
  Cytochrome oxidase subunit II; KEGG: plu:plu2042 2.2e-56 unnamed protein product; similar to quinol oxidase subunit II K00426; Psort location: CytoplasmicMembrane, score: 9.46.


ensembl_gene_id: PROVRUST_05126
symbol: PhoH
gene_biotype: protein_coding
description:
  PhoH family protein; KEGG: reh:H16_A0527 4.0e-41 phoH; phosphate starvation-inducible protein PhoH,predicted ATPase; Psort location: Cytoplasmic, score: 9.97.


ensembl_gene_id: PROVRUST_05128
symbol: EndA
gene_biotype: protein_coding
description:
  Nuclease, EndA/NucM family; KEGG: net:Neut_2614 6.8e-94 deoxyribonuclease I K01150; Psort location: Periplasmic, score: 9.44.


ensembl_gene_id: PROVRUST_05140
symbol: ttcA
gene_biotype: protein_coding
description:
  PP-loop family protein; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.


ensembl_gene_id: PROVRUST_05142
symbol: MppA_1
gene_biotype: protein_coding
description:
  ABC transporter, substrate-binding protein, family 5; KEGG: shn:Shewana3_2650 5.1e-23 acetate kinase K00925; Psort location: Periplasmic, score: 9.44.


ensembl_gene_id: PROVRUST_05143
symbol: tpx
gene_biotype: protein_coding
description:
  Redoxin family protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily.


ensembl_gene_id: PROVRUST_05146
symbol: TyrR
gene_biotype: protein_coding
description:
  Sigma-54 interaction domain protein; KEGG: eci:UTI89_C2502 1.7e-56 atoC; acetoacetate metabolism regulatory protein AtoC K07714.


ensembl_gene_id: PROVRUST_05152
symbol: pspA
gene_biotype: protein_coding
description:
  Phage shock protein A; KEGG: cpf:CPF_1681 0.00026 clpB; ClpB protein K03695; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_05153
symbol: pspF
gene_biotype: protein_coding
description:
  KEGG: eci:UTI89_C1573 3.1e-114 pspF; psp operon transcriptional activator K03974; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_05155
symbol: DppA_2
gene_biotype: protein_coding
description:
  ABC transporter, substrate-binding protein, family 5; KEGG: shn:Shewana3_2650 2.5e-118 acetate kinase K00925; Psort location: Periplasmic, score: 9.44.


ensembl_gene_id: PROVRUST_05156
symbol: SapB_2
gene_biotype: protein_coding
description:
  ABC transporter, permease protein; KEGG: syf:Synpcc7942_2454 1.5e-27 adenine phosphoribosyltransferase K00759; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_05157
symbol: sapC
gene_biotype: protein_coding
description:
  KEGG: lwe:lwe0999 0.00017 gbuB; glycine betaine/L-proline ABC transporter, permease protein; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_05158
symbol: GsiA_4
gene_biotype: protein_coding
description:
  KEGG: rru:Rru_A2359 2.0e-64 oligopeptide/dipeptide ABC transporter, ATP-binding protein-like K06020; Psort location: CytoplasmicMembrane, score: 8.02.


ensembl_gene_id: PROVRUST_05159
symbol: GsiA_3
gene_biotype: protein_coding
description:
  ABC transporter, ATP-binding protein; KEGG: bur:Bcep18194_A6388 3.7e-54 oligopeptide/dipeptide ABC transporter, ATPase subunit K02032; Psort location: Cytoplasmic, score: 9.12.


ensembl_gene_id: PROVRUST_05161
symbol: gstB
gene_biotype: protein_coding
description:
  KEGG: plu:plu2594 6.4e-66 gst; glutathione S-transferase K00799; Psort location: Cytoplasmic, score: 9.26; Belongs to the GST superfamily.


ensembl_gene_id: PROVRUST_05162
symbol: pdxY
gene_biotype: protein_coding
description:
  Pyridoxal kinase; Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP.


ensembl_gene_id: PROVRUST_05163
symbol: tyrS
gene_biotype: protein_coding
description:
  tyrosine--tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.


ensembl_gene_id: PROVRUST_05164
symbol: pdxH
gene_biotype: protein_coding
description:
  Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).


ensembl_gene_id: PROVRUST_05165
symbol: anmK
gene_biotype: protein_coding
description:
  anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family.


ensembl_gene_id: PROVRUST_05168
symbol: slyA
gene_biotype: protein_coding
description:
  Transcriptional regulator SlyA; KEGG: ppr:PBPRA0481 0.00012 hypothetical transcriptional regulator, MarR family K03828; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_05170
symbol: rnt
gene_biotype: protein_coding
description:
  Ribonuclease T; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.


ensembl_gene_id: PROVRUST_05171
symbol: grxD
gene_biotype: protein_coding
description:
  Monothiol glutaredoxin, Grx4 family; KEGG: ama:AM1083 2.0e-07 grxC1; glutaredoxin 3 K03676; Belongs to the glutaredoxin family. Monothiol subfamily.


ensembl_gene_id: PROVRUST_05172
symbol: SodB
gene_biotype: protein_coding
description:
  Superoxide dismutase, Mn/Fe family; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.


ensembl_gene_id: PROVRUST_05173
symbol: purR
gene_biotype: protein_coding
description:
  Sugar-binding domain protein; Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression.


ensembl_gene_id: PROVRUST_05174
symbol: AllS_2
gene_biotype: protein_coding
description:
  LysR substrate binding domain protein; KEGG: shn:Shewana3_3435 2.5e-07 transcriptional regulator, LysR family K06022; Psort location: Cytoplasmic, score: 9.97; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: PROVRUST_05175
symbol: YdhC_2
gene_biotype: protein_coding
description:
  Drug resistance transporter, Bcr/CflA subfamily; KEGG: ani:AN1180.2 6.1e-05 hypothetical protein K04428; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_05176
symbol: EFB73902.1
gene_biotype: protein_coding
description:
  Transcriptional regulator, AraC family; KEGG: aci:ACIAD0344 0.0065 ada; bifunctional protein [includes: transcriptional regulator of DNA repair (AraC/Xyl family); O6-methylguanine-DNA methyltransferase] K00567.


ensembl_gene_id: PROVRUST_05179
symbol: ribE
gene_biotype: protein_coding
description:
  KEGG: plu:plu2610 4.1e-87 ribE; riboflavin synthase alpha chain K00793; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_05180
symbol: mdtK
gene_biotype: protein_coding
description:
  Multidrug efflux protein; Multidrug efflux pump that functions probably as a Na(+)/drug antiporter; Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MdtK subfamily.


ensembl_gene_id: PROVRUST_05184
symbol: pyk-2
gene_biotype: protein_coding
description:
  Pyruvate kinase; KEGG: plu:plu2613 6.5e-208 pykF; pyruvate kinase I (PK-1) K00873; Belongs to the pyruvate kinase family.


ensembl_gene_id: PROVRUST_05187
symbol: sufE
gene_biotype: protein_coding
description:
  Fe-S metabolism associated domain protein; KEGG: cps:CPS_2211 2.7e-18 putative selenocysteine lyase K02426; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_05188
symbol: sufS
gene_biotype: protein_coding
description:
  Cysteine desulfurase, SufS subfamily; Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation. Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L- selenocysteine. Selenocysteine lyase activity is however unsure in vivo.


ensembl_gene_id: PROVRUST_05190
symbol: sufC
gene_biotype: protein_coding
description:
  KEGG: noc:Noc_2489 5.0e-82 sufC; FeS assembly ATPase SufC K09013; Psort location: CytoplasmicMembrane, score: 9.82.


ensembl_gene_id: PROVRUST_05192
symbol: sufA
gene_biotype: protein_coding
description:
  FeS assembly scaffold SufA; Psort location: Cytoplasmic, score: 8.96; Belongs to the HesB/IscA family.


ensembl_gene_id: PROVRUST_05193
symbol: menI
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the hydrolysis of 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA) to 1,4-dihydroxy-2-naphthoate (DHNA).


ensembl_gene_id: PROVRUST_05194
symbol: EFB73917.1
gene_biotype: protein_coding
description:
  FAD linked oxidase, C-terminal domain protein; KEGG: eci:UTI89_C1879 0. ydiJ; hypothetical protein YdiJ; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_05195
symbol: YdiK
gene_biotype: protein_coding
description:
  Hypothetical protein; KEGG: tbd:Tbd_2668 0.00039 phosphoribosylaminoimidazole-succinocarboxamide (SAICAR) synthetase K01923; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_05197
symbol: ppsA
gene_biotype: protein_coding
description:
  Pyruvate, water dikinase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.


ensembl_gene_id: PROVRUST_05198
symbol: YdiA
gene_biotype: protein_coding
description:
  Hypothetical protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.


ensembl_gene_id: PROVRUST_05201
symbol: SoxS_1
gene_biotype: protein_coding
description:
  Transcriptional regulator, AraC family; KEGG: bsu:BG10166 4.3e-12 adaA; methylphosphotriester-DNA alkyltransferase / transcriptional regulator (AraC family) K00567; Psort location: Cytoplasmic, score: 9.97.


ensembl_gene_id: PROVRUST_05202
symbol: lplA
gene_biotype: protein_coding
description:
  Lipoyltransferase and lipoate-protein ligase; Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes. Belongs to the LplA family.


ensembl_gene_id: PROVRUST_05204
symbol: arnF
gene_biotype: protein_coding
description:
  Multidrug resistance protein, SMR family; Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane; Belongs to the ArnF family.


ensembl_gene_id: PROVRUST_05205
symbol: arnE
gene_biotype: protein_coding
description:
  Multidrug resistance protein, SMR family; Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane; Belongs to the ArnE family.


ensembl_gene_id: PROVRUST_05206
symbol: arnT
gene_biotype: protein_coding
description:
  Dolichyl-phosphate-mannose-protein mannosyltransferase; Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides. Belongs to the glycosyltransferase 83 family.


ensembl_gene_id: PROVRUST_05207
symbol: arnD
gene_biotype: protein_coding
description:
  Polysaccharide deacetylase; Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; Belongs to the polysaccharide deacetylase family. ArnD deformylase subfamily.


ensembl_gene_id: PROVRUST_05208
symbol: arnA
gene_biotype: protein_coding
description:
  Bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; In the N-terminal section; belongs to the Fmt family. UDP- L-Ara4N formyltransferase subfamily.


ensembl_gene_id: PROVRUST_05209
symbol: arnC
gene_biotype: protein_coding
description:
  Glycosyltransferase, group 2 family protein; Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.


ensembl_gene_id: PROVRUST_05210
symbol: arnB
gene_biotype: protein_coding
description:
  DegT/DnrJ/EryC1/StrS aminotransferase family protein; Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; Belongs to the DegT/DnrJ/EryC1 family. ArnB subfamily.


ensembl_gene_id: PROVRUST_05211
symbol: BtuD
gene_biotype: protein_coding
description:
  ABC transporter, ATP-binding protein; KEGG: plu:plu2661 1.8e-54 btuD; vitamin B12 transport ATP-binding protein BtuD (Vitamin B12-transporting ATPase) K06074.


ensembl_gene_id: PROVRUST_05212
symbol: btuC
gene_biotype: protein_coding
description:
  Iron chelate uptake ABC transporter, FeCT family, permease protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane.


ensembl_gene_id: PROVRUST_05214
symbol: ihfA
gene_biotype: protein_coding
description:
  Integration host factor, alpha subunit; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.


ensembl_gene_id: PROVRUST_05215
symbol: pheT
gene_biotype: protein_coding
description:
  phenylalanine--tRNA ligase, beta subunit; KEGG: plu:plu2664 0. pheT; phenylalanyl-tRNA synthetase beta chain (phenylalanine--tRNA ligase beta chain) K01890; Psort location: Cytoplasmic, score: 9.97.


ensembl_gene_id: PROVRUST_05216
symbol: pheS
gene_biotype: protein_coding
description:
  phenylalanine--tRNA ligase, alpha subunit; KEGG: yps:YPTB2337 2.0e-158 pheS; phenylalanyl-tRNA synthetase alpha chain K01889; Psort location: Cytoplasmic, score: 9.97; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.


ensembl_gene_id: PROVRUST_05218
symbol: rplT
gene_biotype: protein_coding
description:
  Ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.


ensembl_gene_id: PROVRUST_05220
symbol: infC
gene_biotype: protein_coding
description:
  Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.


ensembl_gene_id: PROVRUST_05223
symbol: thrS
gene_biotype: protein_coding
description:
  threonine--tRNA ligase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).


ensembl_gene_id: PROVRUST_05226
symbol: EFB73948.1
gene_biotype: protein_coding
description:
  Hypothetical protein; KEGG: osa:4336894 6.8e-07 Os04g0602900 K00587; Psort location: CytoplasmicMembrane, score: 9.46.


ensembl_gene_id: PROVRUST_05229
symbol: EmtA_2
gene_biotype: protein_coding
description:
  Transglycosylase SLT domain protein; KEGG: plu:plu2671 2.3e-68 unnamed protein product; similar to membrane-bound lytic murein transglycosylase E (murein hydrolase) K08308.


ensembl_gene_id: PROVRUST_05231
symbol: EFB73953.1
gene_biotype: protein_coding
description:
  ABC transporter, substrate-binding protein; Psort location: CytoplasmicMembrane, score: 8.02; Belongs to the bacterial solute-binding protein 9 family.


ensembl_gene_id: PROVRUST_05235
symbol: EFB73957.1
gene_biotype: protein_coding
description:
  Fructosamine kinase; KEGG: eci:UTI89_C1919 2.5e-87 yniA; hypothetical protein YniA K00924; Psort location: Cytoplasmic, score: 8.96; Belongs to the fructosamine kinase family.


ensembl_gene_id: PROVRUST_05237
symbol: YniC
gene_biotype: protein_coding
description:
  HAD hydrolase, family IA, variant 3; KEGG: eco:b1727 1.1e-63 yniC; predicted hydrolase K01112; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_05239
symbol: TcyP
gene_biotype: protein_coding
description:
  Transporter, dicarboxylate/amino acid:cation Na+/H+ symporter family protein; KEGG: eci:UTI89_C4668 2.8e-33 gltP; glutamate-aspartate symport protein K03309; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: PROVRUST_05243
symbol: EFB73965.1
gene_biotype: protein_coding
description:
  Branched-chain amino acid transport protein (AzlD); Psort location: CytoplasmicMembrane, score: 9.46.


ensembl_gene_id: PROVRUST_05249
symbol: crcB
gene_biotype: protein_coding
description:
  Protein CrcB; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.


ensembl_gene_id: PROVRUST_05250
symbol: YbbL_2
gene_biotype: protein_coding
description:
  KEGG: lpn:lpg1141 8.7e-30 spermidine/putrescine ABC transporter, ATP-binding protein PotA K02052; Psort location: Cytoplasmic, score: 9.12.


ensembl_gene_id: PROVRUST_05252
symbol: RbtD
gene_biotype: protein_coding
description:
  Oxidoreductase, short chain dehydrogenase/reductase family protein; KEGG: rsp:RSP_3704 3.2e-87 ribitol 2-dehydrogenase K00039; Psort location: Cytoplasmic, score: 9.26.


ensembl_gene_id: PROVRUST_05254
symbol: GntR_2
gene_biotype: protein_coding
description:
  KEGG: efa:EF1922 1.1e-10 transcriptional regulator, LacI family/carbohydrate kinase, PfkB family protein K00852; Psort location: Cytoplasmic, score: 9.26.


ensembl_gene_id: PROVRUST_05255
symbol: UlaC_2
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; KEGG: yps:YPTB2600 3.9e-50 PTS system, IIA component, possible mannitol permease K02821; Psort location: CytoplasmicMembrane, score: 9.82.


ensembl_gene_id: PROVRUST_05256
symbol: UlaB
gene_biotype: protein_coding
description:
  PTS system, Lactose/Cellobiose specific IIB subunit; KEGG: ypa:YPA_2059 8.0e-36 hypothetical protein K02822.


ensembl_gene_id: PROVRUST_05257
symbol: UlaA_2
gene_biotype: protein_coding
description:
  Putative sugar-specific permease, SgaT/UlaA; KEGG: mmy:MSC_0395 6.0e-86 conserved hypothetical transmembrane protein K02822:K03475; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_05260
symbol: YfaY
gene_biotype: protein_coding
description:
  Competence/damage-inducible domain protein CinA; KEGG: mmu:319945 6.3e-05 Flad1; RFad1, flavin adenine dinucleotide synthetase, homolog (yeast) K00953; Belongs to the CinA family.


ensembl_gene_id: PROVRUST_05261
symbol: fabV
gene_biotype: protein_coding
description:
  Short-chain alcohol dehydrogenase; Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon- carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP); Belongs to the TER reductase family.


ensembl_gene_id: PROVRUST_05267
symbol: pgsA
gene_biotype: protein_coding
description:
  CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; KEGG: ypk:y2441 1.5e-75 pgsA; phosphatidylglycerophosphate synthetase K00995; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: PROVRUST_05268
symbol: uvrC
gene_biotype: protein_coding
description:
  Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.


ensembl_gene_id: PROVRUST_05269
symbol: UvrY
gene_biotype: protein_coding
description:
  Transcriptional regulator, LuxR family; KEGG: pha:PSHAa1916 4.1e-32 uvrY, sirA; response regulator K07689; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_05270
symbol: pepT
gene_biotype: protein_coding
description:
  Peptidase T; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family.


ensembl_gene_id: PROVRUST_05278
symbol: EFB73996.1
gene_biotype: protein_coding
description:
  Transporter, auxin efflux carrier (AEC) family protein; KEGG: azo:azo2534 1.8e-20 mdcF2; putative malonate transporter; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_05279
symbol: glpX
gene_biotype: protein_coding
description:
  Fructose-1,6-bisphosphatase, class II; KEGG: ypm:YP_0093 2.0e-87 glpX; fructose-1,6-bisphosphatase II / sedoheptulose-1,7-bisphosphatase K02446.


ensembl_gene_id: PROVRUST_05281
symbol: EFB73999.1
gene_biotype: protein_coding
description:
  Sel1 repeat protein; KEGG: eci:UTI89_C1133 2.1e-44 hypothetical protein; Psort location: Extracellular, score: 9.71.


ensembl_gene_id: PROVRUST_05283
symbol: BsaA
gene_biotype: protein_coding
description:
  Glutathione peroxidase; KEGG: ppr:PBPRB1182 3.7e-54 putative glutathione peroxidase K00432; Psort location: Periplasmic, score: 9.44; Belongs to the glutathione peroxidase family.


ensembl_gene_id: PROVRUST_05284
symbol: dpiA
gene_biotype: protein_coding
description:
  Transcriptional regulatory protein DpiA; KEGG: btk:BT9727_0488 1.0e-26 response regulator K07703; Psort location: Cytoplasmic, score: 9.97.


ensembl_gene_id: PROVRUST_05285
symbol: dpiB
gene_biotype: protein_coding
description:
  Sensor kinase DpiB; KEGG: ecc:c0710 3.8e-171 citA; sensor kinase dpiB K07700; Psort location: CytoplasmicMembrane, score: 7.88.


ensembl_gene_id: PROVRUST_05286
symbol: CitC
gene_biotype: protein_coding
description:
  Putative [citrate (pro-3S)-lyase] ligase; KEGG: sbo:SBO_0483 4.6e-72 citC; citrate lyase synthetase K01910; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_05290
symbol: citE
gene_biotype: protein_coding
description:
  KEGG: ssn:SSO_0568 1.1e-130 citE; citrate lyase beta chain; acyl lyase subunit K01660:K01644; Psort location: Cytoplasmic, score: 9.97; Belongs to the HpcH/HpaI aldolase family.


ensembl_gene_id: PROVRUST_05291
symbol: citF
gene_biotype: protein_coding
description:
  Citrate lyase, alpha subunit; KEGG: stm:STM0621 1.0e-209 citF; bifunctional citrate lyase alpha chain/citrate-ACP transferase K01037:K01643; Psort location: Cytoplasmic, score: 9.97.


ensembl_gene_id: PROVRUST_05292
symbol: citX
gene_biotype: protein_coding
description:
  holo-ACP synthase CitX; KEGG: ece:Z0758 6.7e-39 ybdU; hypothetical protein K05964; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_05293
symbol: citG
gene_biotype: protein_coding
description:
  triphosphoribosyl-dephospho-CoA synthase CitG; KEGG: sec:SC0648 4.0e-80 citG; putative modifier of citrate lyase protein K05966; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_05294
symbol: YbhI_3
gene_biotype: protein_coding
description:
  Transporter, DASS family; KEGG: ecj:JW3469 0.0014 arsB; arsenite/antimonite transporter K03893; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_05296
symbol: EFB73208.1
gene_biotype: protein_coding
description:
  HDIG domain protein; KEGG: sat:SYN_01518 0.00092 poly A polymerase K00970; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_05307
symbol: EFB73219.1
gene_biotype: protein_coding
description:
  DNA-binding helix-turn-helix protein; KEGG: reh:H16_A1411 2.4e-05 shikimate kinase containing a XRE-type HTH DNA-binding domain K00924.


ensembl_gene_id: PROVRUST_05312
symbol: EFB73224.1
gene_biotype: protein_coding
description:
  Alkylhydroperoxidase AhpD family core domain protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.


ensembl_gene_id: PROVRUST_05313
symbol: betA
gene_biotype: protein_coding
description:
  Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.


ensembl_gene_id: PROVRUST_05314
symbol: betB
gene_biotype: protein_coding
description:
  Betaine-aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid.


ensembl_gene_id: PROVRUST_05316
symbol: BetP_2
gene_biotype: protein_coding
description:
  Transporter, betaine/carnitine/choline family; KEGG: shn:Shewana3_2719 3.2e-135 choline/carnitine/betaine transporter K01718; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the BCCT transporter (TC 2.A.15) family.


ensembl_gene_id: PROVRUST_05320
symbol: fliA
gene_biotype: protein_coding
description:
  Flagellar biosynthesis sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily.


ensembl_gene_id: PROVRUST_05321
symbol: fliC
gene_biotype: protein_coding
description:
  Flagellin 1; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.


ensembl_gene_id: PROVRUST_05322
symbol: fliD
gene_biotype: protein_coding
description:
  Flagellar hook-associated protein 2; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.


ensembl_gene_id: PROVRUST_05325
symbol: def
gene_biotype: protein_coding
description:
  Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.


ensembl_gene_id: PROVRUST_05335
symbol: fliF
gene_biotype: protein_coding
description:
  Flagellar M-ring protein FliF; The M ring may be actively involved in energy transduction. Belongs to the FliF family.


ensembl_gene_id: PROVRUST_05336
symbol: fliG
gene_biotype: protein_coding
description:
  Flagellar motor switch protein FliG; FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.


ensembl_gene_id: PROVRUST_05338
symbol: fliI
gene_biotype: protein_coding
description:
  Flagellar protein export ATPase FliI; KEGG: plu:plu1945 1.7e-182 fliI; flagellum-specific ATP synthase K02412; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_05339
symbol: fliJ
gene_biotype: protein_coding
description:
  Flagellar export protein FliJ; Flagellar protein that affects chemotactic events. Belongs to the FliJ family.


ensembl_gene_id: PROVRUST_05341
symbol: fliL
gene_biotype: protein_coding
description:
  Flagellar basal body-associated protein FliL; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.


ensembl_gene_id: PROVRUST_05342
symbol: fliM
gene_biotype: protein_coding
description:
  Flagellar motor switch protein FliM; FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.


ensembl_gene_id: PROVRUST_05343
symbol: fliN
gene_biotype: protein_coding
description:
  Flagellar motor switch protein FliN; FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliN/MopA/SpaO family.


ensembl_gene_id: PROVRUST_05345
symbol: fliP
gene_biotype: protein_coding
description:
  Flagellar biosynthetic protein FliP; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family.


ensembl_gene_id: PROVRUST_05346
symbol: fliQ
gene_biotype: protein_coding
description:
  Flagellar biosynthetic protein FliQ; Role in flagellar biosynthesis. Belongs to the FliQ/MopD/SpaQ family.


ensembl_gene_id: PROVRUST_05347
symbol: fliR
gene_biotype: protein_coding
description:
  Flagellar biosynthetic protein FliR; Role in flagellar biosynthesis. Belongs to the FliR/MopE/SpaR family.


ensembl_gene_id: PROVRUST_05352
symbol: flgJ
gene_biotype: protein_coding
description:
  Flagellar rod assembly protein/muramidase FlgJ; KEGG: plu:plu1923 3.4e-92 flgJ; peptidoglycan hydrolase FlgJ (muramidase FlgJ) K02395.


ensembl_gene_id: PROVRUST_05353
symbol: flgI
gene_biotype: protein_coding
description:
  Flagellar P-ring protein FlgI; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.


ensembl_gene_id: PROVRUST_05354
symbol: flgH
gene_biotype: protein_coding
description:
  Flagellar L-ring protein FlgH; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.


ensembl_gene_id: PROVRUST_05358
symbol: flgD
gene_biotype: protein_coding
description:
  Flagellar hook capping protein; Required for flagellar hook formation. May act as a scaffolding protein.


ensembl_gene_id: PROVRUST_05361
symbol: flgB
gene_biotype: protein_coding
description:
  Flagellar basal-body rod protein FlgB; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.


ensembl_gene_id: PROVRUST_05362
symbol: flgA
gene_biotype: protein_coding
description:
  Flagella basal body P-ring formation protein FlgA; Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P- ring assembly; Belongs to the FlgA family.


ensembl_gene_id: PROVRUST_05366
symbol: EFB73278.1
gene_biotype: protein_coding
description:
  Toxin-antitoxin system, antitoxin component, Xre family; KEGG: hhe:HH0028 0.0086 pheS; phenylalanyl-tRNA synthetase alpha subunit K01889; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_05368
symbol: flhA
gene_biotype: protein_coding
description:
  Flagellar biosynthesis protein FlhA; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.


ensembl_gene_id: PROVRUST_05369
symbol: flhB
gene_biotype: protein_coding
description:
  Flagellar biosynthetic protein FlhB; Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the type III secretion exporter family.


ensembl_gene_id: PROVRUST_05371
symbol: CheZ
gene_biotype: protein_coding
description:
  Chemotaxis phosphatase CheZ; Psort location: Cytoplasmic, score: 9.97; overlaps another CDS with the same product name.


ensembl_gene_id: PROVRUST_05372
symbol: EFB73284.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Psort location: Cytoplasmic, score: 8.96; overlaps another CDS with the same product name.


ensembl_gene_id: PROVRUST_05373
symbol: cheY
gene_biotype: protein_coding
description:
  KEGG: eci:UTI89_C2086 7.9e-52 cheY; chemotaxis protein CheY K03413; Psort location: Cytoplasmic, score: 9.97.


ensembl_gene_id: PROVRUST_05374
symbol: cheB
gene_biotype: protein_coding
description:
  Chemotaxis response regulator protein-glutamate methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.


ensembl_gene_id: PROVRUST_05375
symbol: cheR
gene_biotype: protein_coding
description:
  CheR methyltransferase, SAM binding domain protein; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.


ensembl_gene_id: PROVRUST_05376
symbol: Tap_2
gene_biotype: protein_coding
description:
  Methyl-accepting chemotaxis protein signaling domain protein; KEGG: sha:SH0018 1.6e-06 vicK; signal transduction two-component sensor histidine kinase, VicK K07652; Psort location: CytoplasmicMembrane, score: 9.82.


ensembl_gene_id: PROVRUST_05377
symbol: Tsr
gene_biotype: protein_coding
description:
  Methyl-accepting chemotaxis protein signaling domain protein; KEGG: bca:BCE_1090 3.9e-08 sensor histidine kinase/response regulator K03407; Psort location: CytoplasmicMembrane, score: 9.82.


ensembl_gene_id: PROVRUST_05379
symbol: cheW
gene_biotype: protein_coding
description:
  Chemotaxis protein CheW; KEGG: eci:UTI89_C2090 4.4e-58 cheW; CheW positive regulator of CheA protein activity K03408; Psort location: Cytoplasmic, score: 9.97.


ensembl_gene_id: PROVRUST_05380
symbol: CheA
gene_biotype: protein_coding
description:
  CheW-like protein; KEGG: plu:plu1851 2.6e-204 cheA; chemotaxis protein CheA K03407; Psort location: Cytoplasmic, score: 9.97.


ensembl_gene_id: PROVRUST_05383
symbol: flhC
gene_biotype: protein_coding
description:
  Flagellar transcriptional activator FlhC; Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhC family.


ensembl_gene_id: PROVRUST_05384
symbol: flhD
gene_biotype: protein_coding
description:
  Transcriptional activator FlhD; Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhD family.


ensembl_gene_id: PROVRUST_05404
symbol: EFB73316.1
gene_biotype: protein_coding
description:
  Phage capsid scaffolding protein GpO; KEGG: bld:BLi03964 0.0014 rpoE; RNA polymerase (delta subunit); RBL01619 K03048.


ensembl_gene_id: PROVRUST_05427
symbol: CycA
gene_biotype: protein_coding
description:
  Amino acid permease; KEGG: eci:UTI89_C0120 1.1e-91 aroP; aromatic amino acid transport protein AroP K03293; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_05428
symbol: putP
gene_biotype: protein_coding
description:
  Sodium/proline symporter; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: PROVRUST_05429
symbol: PutA
gene_biotype: protein_coding
description:
  Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family.  In the N-terminal section; belongs to the proline dehydrogenase family.


ensembl_gene_id: PROVRUST_05434
symbol: mgtA
gene_biotype: protein_coding
description:
  KEGG: ypa:YPA_1860 0. Mg(2+) transport ATPase protein B K01531; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_05435
symbol: SapB_1
gene_biotype: protein_coding
description:
  KEGG: bpm:BURPS1710b_A2486 1.7e-42 MgtC family protein K07507; Psort location: CytoplasmicMembrane, score: 9.46.


ensembl_gene_id: PROVRUST_05441
symbol: pyrC
gene_biotype: protein_coding
description:
  Dihydroorotase, homodimeric type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.


ensembl_gene_id: PROVRUST_05443
symbol: RcsA
gene_biotype: protein_coding
description:
  Hypothetical protein; KEGG: ava:Ava_B0029 0.0042 two component transcriptional regulator, LuxR family; overlaps another CDS with the same product name.


ensembl_gene_id: PROVRUST_05444
symbol: EFB73352.1
gene_biotype: protein_coding
description:
  Transcriptional regulator, LuxR family; KEGG: eci:UTI89_C1417 0.0014 narL; NarL transcriptional dual regulator K07684; overlaps another CDS with the same product name.


ensembl_gene_id: PROVRUST_05445
symbol: MoeZ
gene_biotype: protein_coding
description:
  Rhodanese-like protein; KEGG: pub:SAR11_1074 9.3e-26 yceA; rhodanese domain protein; Psort location: Cytoplasmic, score: 8.96; Belongs to the UPF0176 family.


ensembl_gene_id: PROVRUST_05446
symbol: PsrA
gene_biotype: protein_coding
description:
  Molybdopterin dinucleotide binding domain protein; KEGG: afu:AF0159 2.6e-95 molybdopterin oxidoreductase, molybdopterin binding subunit K00183; Psort location: Cytoplasmic, score: 8.96; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: PROVRUST_05447
symbol: EFB73355.1
gene_biotype: protein_coding
description:
  Polysulfide reductase, NrfD; KEGG: afu:AF2386 3.1e-11 molybdopterin oxidoreductase, membrane subunit K00185; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_05448
symbol: DdhB
gene_biotype: protein_coding
description:
  Tat pathway signal sequence domain protein; KEGG: pai:PAE1263 1.1e-47 molybdopterin oxidoreductase, iron-sulfur binding subunit K00184; Psort location: Cytoplasmic, score: 9.97.


ensembl_gene_id: PROVRUST_05450
symbol: FixL
gene_biotype: protein_coding
description:
  ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: stm:STM1386 1.3e-152 ttrS; sensory histidine kinase K00873; Psort location: CytoplasmicMembrane, score: 9.82.


ensembl_gene_id: PROVRUST_05451
symbol: FixJ_1
gene_biotype: protein_coding
description:
  Response regulator receiver domain protein; KEGG: rru:Rru_A1500 8.5e-22 signal transduction histidine kinase (STHK) with CheB and CheR activity K03412:K00575; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_05452
symbol: lpxL
gene_biotype: protein_coding
description:
  Lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase; Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A).


ensembl_gene_id: PROVRUST_05453
symbol: TetA
gene_biotype: protein_coding
description:
  Transporter, major facilitator family protein; KEGG: bcz:BCZK2057 0.00029 macrolide efflux protein K00953; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_05455
symbol: YddE
gene_biotype: protein_coding
description:
  Phenazine biosynthesis protein, PhzF family; KEGG: reh:H16_A2781 8.7e-08 predicted epimerase, PhzC/PhzF homolog; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_05456
symbol: EFB73364.1
gene_biotype: protein_coding
description:
  Thioesterase family protein; KEGG: dra:DR0279 3.1e-18 putative acyl-CoA thioester hydrolase K01076; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_05458
symbol: HcpC_1
gene_biotype: protein_coding
description:
  Sel1 repeat protein; KEGG: cch:Cag_1938 4.3e-28 Sel1-like repeat; Psort location: Extracellular, score: 9.71.


ensembl_gene_id: PROVRUST_05460
symbol: Agp
gene_biotype: protein_coding
description:
  Histidine acid phosphatase; KEGG: eci:UTI89_C1065 2.1e-115 agp; periplasmic glucose-1-phosphatase K01085; Psort location: Periplasmic, score: 9.44.


ensembl_gene_id: PROVRUST_05461
symbol: YjaB
gene_biotype: protein_coding
description:
  Acetyltransferase, GNAT family; KEGG: plu:plu3511 9.6e-40 unnamed protein product; similar to hypothetical acetyltransferase YjaB of Escherichia coli K03827; overlaps another CDS with the same product name.


ensembl_gene_id: PROVRUST_05462
symbol: EFB73370.1
gene_biotype: protein_coding
description:
  Acetyltransferase, GNAT family; KEGG: ddi:DDB0216844 1.4e-15 hypothetical protein K00676; overlaps another CDS with the same product name.


ensembl_gene_id: PROVRUST_05463
symbol: FdnI
gene_biotype: protein_coding
description:
  Formate dehydrogenase, gamma subunit; KEGG: ecj:JW1472 2.3e-100 fdnI; formate dehydrogenase-N, cytochrome B556 (gamma) subunit, nitrate-inducible K08350; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_05464
symbol: fdxH
gene_biotype: protein_coding
description:
  Formate dehydrogenase, beta subunit; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers.


ensembl_gene_id: PROVRUST_05465
symbol: EFB73373.1
gene_biotype: protein_coding
description:
  KEGG: eci:UTI89_C1689 0. fdnG; FdnG, alpha subunit of formate dehydrogenase-N K08348; Psort location: Periplasmic, score: 9.44; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: PROVRUST_05466
symbol: EFB73374.1
gene_biotype: protein_coding
description:
  Tat pathway signal sequence domain protein; KEGG: spt:SPA1298 9.2e-90 fdnG; putative molybdopterin oxidoreductases K08348; Psort location: Periplasmic, score: 9.44.


ensembl_gene_id: PROVRUST_05467
symbol: YnfA
gene_biotype: protein_coding
description:
  Hypothetical protein; KEGG: rle:pRL110297 0.0050 hyfB; putative hydrogenase-4 component B; Psort location: CytoplasmicMembrane, score: 9.46.


ensembl_gene_id: PROVRUST_05473
symbol: GcvA_1
gene_biotype: protein_coding
description:
  LysR substrate binding domain protein; KEGG: shn:Shewana3_3435 0.0059 transcriptional regulator, LysR family K06022; Psort location: Cytoplasmic, score: 9.97; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: PROVRUST_05474
symbol: SoxA
gene_biotype: protein_coding
description:
  Tat pathway signal sequence domain protein; KEGG: ret:RHE_PF00356 7.8e-45 putative D-amino acid oxidase protein K00301.


ensembl_gene_id: PROVRUST_05476
symbol: tusE
gene_biotype: protein_coding
description:
  Sulfur relay protein, TusE/DsrC/DsvC family; KEGG: plu:plu1786 7.3e-42 unnamed protein product; highly similar to probable sulfite reductase gamma chain YccK of Escherichia coli K00396; Psort location: Cytoplasmic, score: 9.26.


ensembl_gene_id: PROVRUST_05477
symbol: YccX
gene_biotype: protein_coding
description:
  Acylphosphatase; KEGG: plu:plu1785 8.6e-23 unnamed protein product; similar to probable acylphosphatase YccX of Escherichia coli K01512.


ensembl_gene_id: PROVRUST_05478
symbol: hspQ
gene_biotype: protein_coding
description:
  Hemimethylated DNA binding domain protein; Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress; Belongs to the HspQ family.


ensembl_gene_id: PROVRUST_05479
symbol: YccU
gene_biotype: protein_coding
description:
  CoA binding domain protein; KEGG: rru:Rru_A2075 4.0e-27 O-acetylhomoserine/O-acetylserine sulfhydrylase K01740.


ensembl_gene_id: PROVRUST_05481
symbol: HelD
gene_biotype: protein_coding
description:
  UvrD/REP helicase; KEGG: yps:YPTB1458 1.6e-257 putative DNA helicase IV K03658; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_05482
symbol: yccS
gene_biotype: protein_coding
description:
  TIGR01666 family membrane protein; KEGG: ssn:SSO_3489 1.0e-28 yhfK; hypothetical protein K01823; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_05484
symbol: sulA
gene_biotype: protein_coding
description:
  Cell division inhibitor SulA; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.


ensembl_gene_id: PROVRUST_05485
symbol: OmpA
gene_biotype: protein_coding
description:
  OmpA-like transmembrane domain protein; KEGG: bte:BTH_I0426 0.0089 cytochrome c oxidase, subunit II K02275; Psort location: OuterMembrane, score: 10.00; Belongs to the outer membrane OOP (TC 1.B.6) superfamily.


ensembl_gene_id: PROVRUST_05486
symbol: matP
gene_biotype: protein_coding
description:
  Hypothetical protein; Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain.


ensembl_gene_id: PROVRUST_05487
symbol: Lon_2
gene_biotype: protein_coding
description:
  Hypothetical protein; KEGG: plu:plu1773 5.0e-169 unnamed protein product; similar to putative protease La homolog, YcbZ of Escherichia coli K04770; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_05488
symbol: fabA
gene_biotype: protein_coding
description:
  Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.


ensembl_gene_id: PROVRUST_05489
symbol: rmf
gene_biotype: protein_coding
description:
  Ribosome modulation factor; During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes); Belongs to the ribosome modulation factor family.


ensembl_gene_id: PROVRUST_05494
symbol: rlmL
gene_biotype: protein_coding
description:
  THUMP domain protein; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family.


ensembl_gene_id: PROVRUST_05496
symbol: zapC
gene_biotype: protein_coding
description:
  Hypothetical protein; Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ.


ensembl_gene_id: PROVRUST_05497
symbol: pyrD
gene_biotype: protein_coding
description:
  Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.


ensembl_gene_id: PROVRUST_05498
symbol: pepN
gene_biotype: protein_coding
description:
  Membrane alanyl aminopeptidase; KEGG: plu:plu1755 0. pepN; aminopeptidase N K01256; Psort location: Cytoplasmic, score: 9.12.


ensembl_gene_id: PROVRUST_05499
symbol: pncB
gene_biotype: protein_coding
description:
  Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family.


ensembl_gene_id: PROVRUST_05500
symbol: asnS
gene_biotype: protein_coding
description:
  asparagine--tRNA ligase; KEGG: plu:plu1753 2.8e-223 asnS; asparaginyl-tRNA synthetase K01893; Psort location: Cytoplasmic, score: 9.97.


ensembl_gene_id: PROVRUST_05501
symbol: OmpC
gene_biotype: protein_coding
description:
  Gram-negative porin; Psort location: OuterMembrane, score: 10.00; Belongs to the Gram-negative porin family.


ensembl_gene_id: PROVRUST_05503
symbol: AspC_2
gene_biotype: protein_coding
description:
  Aminotransferase, class I/II; KEGG: plu:plu1750 1.1e-175 aspC; aspartate aminotransferase (transaminase A) K00813; Psort location: Cytoplasmic, score: 9.26.


ensembl_gene_id: PROVRUST_05504
symbol: Cya_1
gene_biotype: protein_coding
description:
  Putative phage head-tail adaptor; KEGG: bpa:BPP0321 3.0e-34 cyaA, cya; bifunctional hemolysin-adenylate cyclase precursor K01768; Psort location: Extracellular, score: 10.00.


ensembl_gene_id: PROVRUST_05505
symbol: EFB73412.1
gene_biotype: protein_coding
description:
  Metallo-beta-lactamase domain protein; KEGG: eci:UTI89_C0999 1.6e-78 ycbL; hypothetical protein K01069.


ensembl_gene_id: PROVRUST_05508
symbol: aphA
gene_biotype: protein_coding
description:
  HAD phosphatase, family IIIB; KEGG: spt:SPA4066 1.5e-80 aphA; class B acid phosphatase precursor K03788; Belongs to the class B bacterial acid phosphatase family.


ensembl_gene_id: PROVRUST_05509
symbol: MukB
gene_biotype: protein_coding
description:
  KEGG: eci:UTI89_C0996 0. mukB; cell division protein MukB K03632; Belongs to the SMC family. MukB subfamily.


ensembl_gene_id: PROVRUST_05510
symbol: mukE
gene_biotype: protein_coding
description:
  MukE-like family protein; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF.


ensembl_gene_id: PROVRUST_05511
symbol: MukF
gene_biotype: protein_coding
description:
  KicB killing factor; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity.


ensembl_gene_id: PROVRUST_05512
symbol: cmoM
gene_biotype: protein_coding
description:
  Methyltransferase domain protein; Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs; Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoM family.


ensembl_gene_id: PROVRUST_05514
symbol: kdsB
gene_biotype: protein_coding
description:
  3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.


ensembl_gene_id: PROVRUST_05515
symbol: YcaR
gene_biotype: protein_coding
description:
  Hypothetical protein; KEGG: neu:NE2164 2.0e-15 lpxK; tetraacyldisaccharide-1-P 4'-kinase K00912; Psort location: Cytoplasmic, score: 8.96; Belongs to the UPF0434 family.


ensembl_gene_id: PROVRUST_05518
symbol: lpxK
gene_biotype: protein_coding
description:
  Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).


ensembl_gene_id: PROVRUST_05519
symbol: msbA
gene_biotype: protein_coding
description:
  Lipid A export permease/ATP-binding protein MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.


ensembl_gene_id: PROVRUST_05520
symbol: EFB73427.1
gene_biotype: protein_coding
description:
  DNA internalization competence protein ComEC/Rec2-like protein; KEGG: lpn:lpg1295 0.00042 hydroxyacylglutathione hydrolase GloB K01069; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_05521
symbol: ihfB
gene_biotype: protein_coding
description:
  Integration host factor, beta subunit; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.


ensembl_gene_id: PROVRUST_05522
symbol: rpsA
gene_biotype: protein_coding
description:
  Ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.


ensembl_gene_id: PROVRUST_05523
symbol: cmk
gene_biotype: protein_coding
description:
  Cytidylate kinase; KEGG: plu:plu1621 2.2e-97 mssA; cytidylate kinase (CK) (cytidine monophosphate kinase) (CMP kinase) (MssA protein) (P25) K00945.


ensembl_gene_id: PROVRUST_05524
symbol: aroA
gene_biotype: protein_coding
description:
  3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.


ensembl_gene_id: PROVRUST_05525
symbol: serC
gene_biotype: protein_coding
description:
  Phosphoserine transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.


ensembl_gene_id: PROVRUST_05526
symbol: pgm
gene_biotype: protein_coding
description:
  Phosphoglucomutase, alpha-D-glucose phosphate-specific; KEGG: sfl:SF0605 2.9e-228 pgm; phosphoglucomutase K01835.


ensembl_gene_id: PROVRUST_05527
symbol: seqA
gene_biotype: protein_coding
description:
  SeqA protein; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated.


ensembl_gene_id: PROVRUST_05528
symbol: YbfF
gene_biotype: protein_coding
description:
  Hydrolase, alpha/beta domain protein; KEGG: plu:plu3206 1.0e-83 unnamed protein product; similar to putative esterase/lipase, YbfF protein of Escherichia coli; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_05529
symbol: ApxIB_2
gene_biotype: protein_coding
description:
  Type I secretion system ATPase; KEGG: aha:AHA_1356 1.5e-190 rtxB; RTX toxin transporter; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_05530
symbol: HlyD_2
gene_biotype: protein_coding
description:
  Type I secretion membrane fusion protein, HlyD family; KEGG: lsl:LSL_1369 0.00047 sbcC; exonuclease K01146; Psort location: CytoplasmicMembrane, score: 8.02.


ensembl_gene_id: PROVRUST_05531
symbol: HlyB
gene_biotype: protein_coding
description:
  Type I secretion system ATPase; KEGG: ava:Ava_1188 4.2e-129 cyclic nucleotide-regulated ABC bacteriocin/lantibiotic exporters K06147; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_05533
symbol: FldA
gene_biotype: protein_coding
description:
  Flavodoxin; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family.


ensembl_gene_id: PROVRUST_05534
symbol: fur
gene_biotype: protein_coding
description:
  Ferric uptake regulation protein; Psort location: Cytoplasmic, score: 9.97; Belongs to the Fur family.


ensembl_gene_id: PROVRUST_05536
symbol: AnsB
gene_biotype: protein_coding
description:
  L-asparaginase, type II; KEGG: plu:plu1616 7.4e-136 ansB; L-asparaginase II precursor (L-asparagine amidohydrolase II) (L-asnase II) (colaspase) K01424; Psort location: Periplasmic, score: 9.44; Belongs to the asparaginase 1 family.


ensembl_gene_id: PROVRUST_05538
symbol: focA
gene_biotype: protein_coding
description:
  Formate transporter FocA; KEGG: shn:Shewana3_1556 6.7e-71 methionine gamma-lyase K01761; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_05539
symbol: pflB
gene_biotype: protein_coding
description:
  KEGG: plu:plu1613 0. pflB; formate acetyltransferase I (pyruvate formate-lyase 1) K00656; Psort location: Cytoplasmic, score: 9.97.


ensembl_gene_id: PROVRUST_05540
symbol: pflA
gene_biotype: protein_coding
description:
  KEGG: ypn:YPN_2596 2.9e-93 pyruvate formate-lyase 1 activating enzyme K04069; Psort location: Cytoplasmic, score: 9.97.


ensembl_gene_id: PROVRUST_05542
symbol: serS
gene_biotype: protein_coding
description:
  serine--tRNA ligase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).


ensembl_gene_id: PROVRUST_05543
symbol: RarA
gene_biotype: protein_coding
description:
  Recombination factor protein RarA; KEGG: pha:PSHAa1714 2.0e-142 rarA; polynucleotide enzyme with nucleotide triphosphate hydrolase domain K07478.


ensembl_gene_id: PROVRUST_05544
symbol: lolA
gene_biotype: protein_coding
description:
  Outer membrane lipoprotein carrier protein LolA; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).


ensembl_gene_id: PROVRUST_05545
symbol: FtsK_1
gene_biotype: protein_coding
description:
  FtsK/SpoIIIE family protein; KEGG: pen:PSEEN2212 1.4e-182 ftsK; cell division protein FtsK; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_05548
symbol: trxB
gene_biotype: protein_coding
description:
  KEGG: plu:plu1599 1.7e-145 trxB; thioredoxin reductase (NADPH) K00384; Psort location: Cytoplasmic, score: 9.97.


ensembl_gene_id: PROVRUST_05550
symbol: cydD
gene_biotype: protein_coding
description:
  Thiol reductant ABC exporter, CydD subunit; KEGG: cch:Cag_0716 2.6e-76 ATPase K06148; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_05551
symbol: cydC
gene_biotype: protein_coding
description:
  Thiol reductant ABC exporter, CydC subunit; KEGG: cch:Cag_0717 8.7e-78 ATPase K06148; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_05552
symbol: aat
gene_biotype: protein_coding
description:
  Leucyltransferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.


ensembl_gene_id: PROVRUST_05553
symbol: infA
gene_biotype: protein_coding
description:
  Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.


ensembl_gene_id: PROVRUST_05554
symbol: clpA
gene_biotype: protein_coding
description:
  KEGG: azo:azo1132 1.2e-247 clpA; probable ATP-dependent Clp protease, ATP-binding subunit ClpA K01358; Psort location: Cytoplasmic, score: 9.26; Belongs to the ClpA/ClpB family.


ensembl_gene_id: PROVRUST_05555
symbol: clpS
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease adaptor protein ClpS; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family.


ensembl_gene_id: PROVRUST_05563
symbol: EFB73470.1
gene_biotype: protein_coding
description:
  Hypothetical protein; KEGG: rpc:RPC_0925 7.8e-05 cytochrome c1 K00413; Psort location: CytoplasmicMembrane, score: 9.46.


ensembl_gene_id: PROVRUST_05565
symbol: EFB73472.1
gene_biotype: protein_coding
description:
  Phage tail tape measure protein, lambda family; KEGG: eci:UTI89_C5128 2.3e-139 putative tail length tape measure protein precursor K00924; Psort location: OuterMembrane, score: 9.49.


ensembl_gene_id: PROVRUST_05575
symbol: clpP
gene_biotype: protein_coding
description:
  Endopeptidase Clp; KEGG: azo:azo1870 2.0e-69 endopeptidase Clp K01358; Psort location: Cytoplasmic, score: 9.26; Belongs to the peptidase S14 family.


ensembl_gene_id: PROVRUST_05590
symbol: purH
gene_biotype: protein_coding
description:
  KEGG: plu:plu0495 1.7e-248 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase and IMP cyclohydrolase (bifunctional enzyme) K00602:K01492; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_05591
symbol: purD
gene_biotype: protein_coding
description:
  Phosphoribosylamine--glycine ligase; KEGG: plu:plu0494 1.7e-182 purD; phosphoribosylglycinamide synthetase K01945; Belongs to the GARS family.


ensembl_gene_id: PROVRUST_05593
symbol: hupA
gene_biotype: protein_coding
description:
  DNA-binding protein HU-alpha; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.


ensembl_gene_id: PROVRUST_05595
symbol: nfi
gene_biotype: protein_coding
description:
  Deoxyribonuclease V; DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.


ensembl_gene_id: PROVRUST_05596
symbol: hemE
gene_biotype: protein_coding
description:
  Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.


ensembl_gene_id: PROVRUST_05597
symbol: nudC
gene_biotype: protein_coding
description:
  Hydrolase, NUDIX family; KEGG: plu:plu0488 1.5e-105 nudC; NADH pyrophosphatase K03659; Psort location: Cytoplasmic, score: 8.96; Belongs to the Nudix hydrolase family. NudC subfamily.


ensembl_gene_id: PROVRUST_05599
symbol: EFB73173.1
gene_biotype: protein_coding
description:
  Type I phosphodiesterase / nucleotide pyrophosphatase; KEGG: aba:Acid345_1449 1.6e-08 phosphodiesterase I K01113; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_05600
symbol: UgpA_1
gene_biotype: protein_coding
description:
  KEGG: cya:CYA_1846 1.6e-06 modB; molybdate ABC transporter, permease protein K02018; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_05601
symbol: CysW_1
gene_biotype: protein_coding
description:
  ABC transporter, permease protein; KEGG: hpa:HPAG1_0451 2.2e-08 molybdenum ABC transporter ModB K06022; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_05602
symbol: PotA_1
gene_biotype: protein_coding
description:
  KEGG: vpa:VPA0350 7.0e-124 putative ATP-binding component of ABC transporter K02052; Psort location: Cytoplasmic, score: 9.12.


ensembl_gene_id: PROVRUST_05604
symbol: sglT
gene_biotype: protein_coding
description:
  Sodium/glucose cotransporter; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: PROVRUST_05605
symbol: GalR
gene_biotype: protein_coding
description:
  KEGG: efa:EF1922 7.3e-11 transcriptional regulator, LacI family/carbohydrate kinase, PfkB family protein K00852; Psort location: Cytoplasmic, score: 9.97.


ensembl_gene_id: PROVRUST_05607
symbol: galK
gene_biotype: protein_coding
description:
  Galactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily.


ensembl_gene_id: PROVRUST_05609
symbol: galE
gene_biotype: protein_coding
description:
  KEGG: vvu:VV1_1770 9.7e-134 UDP-glucose 4-epimerase K01784; Belongs to the NAD(P)-dependent epimerase/dehydratase family.


ensembl_gene_id: PROVRUST_05610
symbol: thiC
gene_biotype: protein_coding
description:
  Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.


ensembl_gene_id: PROVRUST_05611
symbol: thiE
gene_biotype: protein_coding
description:
  Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.


ensembl_gene_id: PROVRUST_05612
symbol: ThiF
gene_biotype: protein_coding
description:
  ThiF family protein; KEGG: eca:ECA0230 2.8e-88 thiF; thiamine biosynthesis adenylyltransferase K03148.


ensembl_gene_id: PROVRUST_05614
symbol: thiG
gene_biotype: protein_coding
description:
  Thiazole biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.


ensembl_gene_id: PROVRUST_05615
symbol: thiH
gene_biotype: protein_coding
description:
  Thiazole biosynthesis protein ThiH; KEGG: tte:TTE1073 1.1e-10 bioB; Biotin synthase and related enzymes K01012.


ensembl_gene_id: PROVRUST_05618
symbol: DcuD_2
gene_biotype: protein_coding
description:
  Transporter, anaerobic C4-dicarboxylate uptake C (DcuC) family; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_05622
symbol: rpoC
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: PROVRUST_05623
symbol: rpoB
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: PROVRUST_05624
symbol: rplL
gene_biotype: protein_coding
description:
  Ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family.


ensembl_gene_id: PROVRUST_05625
symbol: rplJ
gene_biotype: protein_coding
description:
  Ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.


ensembl_gene_id: PROVRUST_05626
symbol: rplA
gene_biotype: protein_coding
description:
  Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.


ensembl_gene_id: PROVRUST_05627
symbol: rplK
gene_biotype: protein_coding
description:
  Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.


ensembl_gene_id: PROVRUST_05628
symbol: nusG
gene_biotype: protein_coding
description:
  Transcription termination/antitermination factor NusG; Participates in transcription elongation, termination and antitermination. In the absence of Rho, increases the rate of transcription elongation by the RNA polymerase (RNAP), probably by partially suppressing pausing. In the presence of Rho, modulates most Rho-dependent termination events by interacting with the RNAP to render the complex more susceptible to the termination activity of Rho. May be required to overcome a kinetic limitation of Rho to function at certain terminators. Also involved in ribosomal RNA transcriptional anti [...]


ensembl_gene_id: PROVRUST_05629
symbol: secE
gene_biotype: protein_coding
description:
  Preprotein translocase, SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61-gamma family.


ensembl_gene_id: PROVRUST_05631
symbol: EFB73205.1
gene_biotype: protein_coding
description:
  KEGG: ypk:y3986 1.0e-26 tufB; elongation factor EF-Tu K02358; Psort location: Cytoplasmic, score: 9.97.


ensembl_gene_id: PROVRUST_05632
symbol: tuf
gene_biotype: protein_coding
description:
  KEGG: plu:plu4730 1.1e-171 tufA; elongation factor Tu (EF-Tu) K02358; Psort location: Cytoplasmic, score: 9.97.


ensembl_gene_id: PROVRUST_05633
symbol: fusA
gene_biotype: protein_coding
description:
  Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...]


ensembl_gene_id: PROVRUST_05634
symbol: rpsG
gene_biotype: protein_coding
description:
  Ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.


ensembl_gene_id: PROVRUST_05635
symbol: rpsL
gene_biotype: protein_coding
description:
  Ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.


ensembl_gene_id: PROVRUST_05636
symbol: dsrH
gene_biotype: protein_coding
description:
  Sulfur relay protein TusB/DsrH; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.


ensembl_gene_id: PROVRUST_05638
symbol: tusD
gene_biotype: protein_coding
description:
  Sulfur relay protein TusD/DsrE; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE.


ensembl_gene_id: PROVRUST_05640
symbol: FkpA
gene_biotype: protein_coding
description:
  KEGG: plu:plu0424 1.9e-89 fkpA; FKBP-type peptidyl-prolyl cis-trans isomerase (rotamase) K03772; Psort location: Periplasmic, score: 9.44.


ensembl_gene_id: PROVRUST_05641
symbol: slyX
gene_biotype: protein_coding
description:
  SlyX family protein; KEGG: sha:SH2593 0.0094 ahpF; alkyl hydroperoxide reductase subunit F K03387; Psort location: Cytoplasmic, score: 8.96; Belongs to the SlyX family.


ensembl_gene_id: PROVRUST_05642
symbol: slyD
gene_biotype: protein_coding
description:
  KEGG: eco:b3349 2.3e-84 slyD; FKBP-type peptidyl prolyl cis-trans isomerase (rotamase) K03775; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_05644
symbol: kefB
gene_biotype: protein_coding
description:
  Transporter, CPA2 family; Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport.


ensembl_gene_id: PROVRUST_05645
symbol: kefG
gene_biotype: protein_coding
description:
  Flavodoxin-like protein; Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefB.


ensembl_gene_id: PROVRUST_05646
symbol: YheS_2
gene_biotype: protein_coding
description:
  KEGG: bur:Bcep18194_A5345 2.8e-184 ABC transporter, fused ATPase subunits K06158; Psort location: CytoplasmicMembrane, score: 9.82.


ensembl_gene_id: PROVRUST_05649
symbol: adiA
gene_biotype: protein_coding
description:
  KEGG: ecc:c5122 0. adiA; biodegradative arginine decarboxylase K01584; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_05650
symbol: EFB72853.1
gene_biotype: protein_coding
description:
  Taurine catabolism dioxygenase, TauD/TfdA family; KEGG: bxe:Bxe_B2141 4.9e-07 putative alpha KG dependent 2,4-D dioxygenase.


ensembl_gene_id: PROVRUST_05652
symbol: murQ
gene_biotype: protein_coding
description:
  N-acetylmuramic acid 6-phosphate etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.


ensembl_gene_id: PROVRUST_05653
symbol: MurP
gene_biotype: protein_coding
description:
  Phosphotransferase system, EIIC; KEGG: plu:plu0402 2.4e-178 unnamed protein product; highly similar to putative PTS system IIBC component, YfeV protein of Escherichia coli K02809:K02810; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_05657
symbol: CfxP
gene_biotype: protein_coding
description:
  Phosphoribulokinase/uridine kinase family protein; KEGG: plu:plu0397 9.6e-127 prkB; phosphoribulokinase K00855.


ensembl_gene_id: PROVRUST_05659
symbol: crp
gene_biotype: protein_coding
description:
  Catabolite protein activator; KEGG: eci:UTI89_C3860 1.0e-106 crp; CRP-cAMP transcriptional dual regulator K00924; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_05662
symbol: argD
gene_biotype: protein_coding
description:
  Bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.


ensembl_gene_id: PROVRUST_05663
symbol: TrpG_1
gene_biotype: protein_coding
description:
  KEGG: plu:plu0393 2.2e-88 pabA; para-aminobenzoate synthase glutamine amidotransferase, component II K01664; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_05664
symbol: PpiA
gene_biotype: protein_coding
description:
  Peptidyl-prolyl cis-trans isomerase, cyclophilin-type; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.


ensembl_gene_id: PROVRUST_05665
symbol: ysxC
gene_biotype: protein_coding
description:
  Ribosome biogenesis GTP-binding protein YsxC; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.


ensembl_gene_id: PROVRUST_05668
symbol: polA
gene_biotype: protein_coding
description:
  DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.


ensembl_gene_id: PROVRUST_05670
symbol: DsbA
gene_biotype: protein_coding
description:
  DsbA-like protein; KEGG: bci:BCI_0257 1.5e-50 dsbA; thiol:disulfide interchange protein DsbA K01829; Psort location: Periplasmic, score: 9.44.


ensembl_gene_id: PROVRUST_05671
symbol: srkA
gene_biotype: protein_coding
description:
  Phosphotransferase enzyme family; A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.


ensembl_gene_id: PROVRUST_05673
symbol: mobA
gene_biotype: protein_coding
description:
  Molybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family.


ensembl_gene_id: PROVRUST_05677
symbol: UgpC_1
gene_biotype: protein_coding
description:
  KEGG: rme:Rmet_2052 6.4e-82 ABC transporter-related protein K05816; Psort location: Cytoplasmic, score: 9.12.


ensembl_gene_id: PROVRUST_05680
symbol: EFB72882.1
gene_biotype: protein_coding
description:
  ABC transporter, solute-binding protein; KEGG: eci:UTI89_C1581 1.9e-07 ycjN; putative ABC transporter periplasmic binding protein YcjN precursor K02027.


ensembl_gene_id: PROVRUST_05682
symbol: Gst
gene_biotype: protein_coding
description:
  Glutathione S-transferase, N-terminal domain protein; KEGG: cvi:CV1164 3.2e-39 gst1; glutathione S-transferase family protein K00799.


ensembl_gene_id: PROVRUST_05685
symbol: gor
gene_biotype: protein_coding
description:
  KEGG: eca:ECA0062 8.4e-215 gor; glutathione reductase K00383; Psort location: Cytoplasmic, score: 9.97.


ensembl_gene_id: PROVRUST_05688
symbol: YhjD
gene_biotype: protein_coding
description:
  Putative ribonuclease; KEGG: eci:UTI89_C4054 6.0e-102 yhjD; hypothetical protein; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_05689
symbol: EFB72891.1
gene_biotype: protein_coding
description:
  Oxidoreductase, 2-nitropropane dioxygenase family protein; KEGG: bur:Bcep18194_A4869 6.8e-94 2-nitropropane dioxygenase, NPD K00459.


ensembl_gene_id: PROVRUST_05691
symbol: EFB72893.1
gene_biotype: protein_coding
description:
  Beta-lactamase; KEGG: bcz:BCZK2755 3.5e-17 adp; D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein) K01286.


ensembl_gene_id: PROVRUST_05692
symbol: YhjJ_1
gene_biotype: protein_coding
description:
  Peptidase M16 inactive domain protein; KEGG: ypm:YP_3354 2.9e-125 pqqL; putative insulinase family protease K07263.


ensembl_gene_id: PROVRUST_05694
symbol: YhjK
gene_biotype: protein_coding
description:
  HAMP domain protein; KEGG: lpl:lp_0037 0.0024 hpk1; histidine protein kinase; sensor protein K07652.


ensembl_gene_id: PROVRUST_05696
symbol: GsiA_2
gene_biotype: protein_coding
description:
  KEGG: pen:PSEEN1053 4.4e-99 dppF; dipeptide ABC transporter, ATP-binding protein; Belongs to the ABC transporter superfamily.


ensembl_gene_id: PROVRUST_05697
symbol: GsiA_1
gene_biotype: protein_coding
description:
  KEGG: rru:Rru_A2359 4.0e-112 oligopeptide/dipeptide ABC transporter, ATP-binding protein-like K06020; Psort location: CytoplasmicMembrane, score: 8.02.


ensembl_gene_id: PROVRUST_05698
symbol: DppC
gene_biotype: protein_coding
description:
  ABC transporter, permease protein; KEGG: bpm:BURPS1710b_A0449 0.00026 glycine betaine/L-proline ABC transporter, permease protein K02001; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_05699
symbol: dppB
gene_biotype: protein_coding
description:
  KEGG: rha:RHA1_ro09047 1.2e-46 ABC peptide transporter, permease component K02033; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_05700
symbol: dppA
gene_biotype: protein_coding
description:
  Dipeptide ABC transporter, periplasmic dipeptide-binding protein DppA; KEGG: shn:Shewana3_2650 4.5e-120 acetate kinase K00925; Psort location: Periplasmic, score: 10.00.


ensembl_gene_id: PROVRUST_05702
symbol: glyS
gene_biotype: protein_coding
description:
  glycine--tRNA ligase, beta subunit; KEGG: plu:plu0294 0. glyS; glycyl-tRNA synthetase beta chain (glycine--TRNA ligase beta chain) (GlyRS) K01879.


ensembl_gene_id: PROVRUST_05703
symbol: glyQ
gene_biotype: protein_coding
description:
  KEGG: ypk:y4090 1.0e-161 glyQ; glycine tRNA synthetase, alpha subunit K01878; Psort location: Cytoplasmic, score: 9.97.


ensembl_gene_id: PROVRUST_05704
symbol: tag
gene_biotype: protein_coding
description:
  KEGG: plu:plu0292 5.6e-67 tag; DNA-3-methyladenine glycosylase I (3-methyladenine-DNA glycosylase I, constitutive) (TAG I) (DNA-3-methyladenine glycosidase I) K01246.


ensembl_gene_id: PROVRUST_05705
symbol: AspC_1
gene_biotype: protein_coding
description:
  Aminotransferase, class I/II; KEGG: plu:plu0291 1.6e-179 avtA; valine--pyruvate aminotransferase (transaminase C) (alanine--valine transaminase) K00835; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_05706
symbol: EFB72907.1
gene_biotype: protein_coding
description:
  TrkA C-terminal domain protein; KEGG: lmo:lmo2772 0.00084 similar to beta-glucoside-specific enzyme IIABC K02755:K02756:K02757; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_05710
symbol: ligA
gene_biotype: protein_coding
description:
  NAD-dependent DNA ligase OB-fold domain protein; Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. Belongs to the NAD-dependent DNA ligase family. LigB subfamily.


ensembl_gene_id: PROVRUST_05712
symbol: rpoZ
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.


ensembl_gene_id: PROVRUST_05713
symbol: SpoT
gene_biotype: protein_coding
description:
  RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.


ensembl_gene_id: PROVRUST_05714
symbol: trmH
gene_biotype: protein_coding
description:
  RNA methyltransferase, TrmH family; Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.


ensembl_gene_id: PROVRUST_05715
symbol: recG
gene_biotype: protein_coding
description:
  ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily.


ensembl_gene_id: PROVRUST_05716
symbol: gltS
gene_biotype: protein_coding
description:
  Sodium/glutamate symporter; Catalyzes the sodium-dependent transport of glutamate. Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.


ensembl_gene_id: PROVRUST_05717
symbol: XanP
gene_biotype: protein_coding
description:
  Putative permease; KEGG: hpa:HPAG1_1114 0.00064 hypothetical protein K00760; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_05719
symbol: EFB72920.1
gene_biotype: protein_coding
description:
  Putative thioesterase domain protein; KEGG: eci:UTI89_C4472 2.8e-111 yiiD; putative acetyltransferase K00633; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_05720
symbol: dtd
gene_biotype: protein_coding
description:
  D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family.


ensembl_gene_id: PROVRUST_05721
symbol: YihX
gene_biotype: protein_coding
description:
  HAD hydrolase, family IA, variant 3; KEGG: cel:K09H11.1 5.2e-12 K09H11.1 K00249; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_05723
symbol: typA
gene_biotype: protein_coding
description:
  GTP-binding protein TypA; KEGG: eci:UTI89_C4460 2.8e-287 typA, bipA, yihK, yjhK; putative GTP-binding factor K06207; Psort location: Cytoplasmic, score: 9.97.


ensembl_gene_id: PROVRUST_05726
symbol: glnA
gene_biotype: protein_coding
description:
  KEGG: plu:plu0237 1.1e-230 glnA; glutamine synthetase (glutamate--ammonia ligase) K01915; Psort location: Cytoplasmic, score: 9.97.


ensembl_gene_id: PROVRUST_05727
symbol: GlnL
gene_biotype: protein_coding
description:
  ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: plu:plu0236 1.6e-140 glnL; nitrogen regulation protein K07708; Psort location: CytoplasmicMembrane, score: 9.82.


ensembl_gene_id: PROVRUST_05728
symbol: ntrC
gene_biotype: protein_coding
description:
  Nitrogen regulation protein; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.


ensembl_gene_id: PROVRUST_05731
symbol: FimD_6
gene_biotype: protein_coding
description:
  Fimbrial usher protein; KEGG: ddi:DDB0230105 1.7e-08 putative CLK family kinase K08287; Psort location: OuterMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_05738
symbol: FimD_4
gene_biotype: protein_coding
description:
  Fimbrial usher protein; KEGG: ddi:DDB0230105 0.0018 putative CLK family kinase K08287; Psort location: OuterMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_05742
symbol: EFB72943.1
gene_biotype: protein_coding
description:
  DNA-binding helix-turn-helix protein; KEGG: mmo:MMOB3450 0.00063 dam; adenine-specific DNA methyltransferase K06223.


ensembl_gene_id: PROVRUST_05743
symbol: EFB72944.1
gene_biotype: protein_coding
description:
  DNA-binding helix-turn-helix protein; KEGG: bxe:Bxe_C0924 2.7e-06 transcriptional regulator, XRE family with shikimate kinase activity K00891; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_05744
symbol: EFB72945.1
gene_biotype: protein_coding
description:
  Fimbrial protein; KEGG: chu:CHU_0841 0.0022 CHU large protein; uncharacterized K01238; Psort location: Extracellular, score: 9.71.


ensembl_gene_id: PROVRUST_05748
symbol: FimD_3
gene_biotype: protein_coding
description:
  Fimbrial usher protein; KEGG: ddi:DDB0230105 0.00025 putative CLK family kinase K08287; Psort location: OuterMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_05752
symbol: EFB72953.1
gene_biotype: protein_coding
description:
  DNA-binding helix-turn-helix protein; KEGG: pac:PPA1226 0.0039 UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790.


ensembl_gene_id: PROVRUST_05755
symbol: EFB72956.1
gene_biotype: protein_coding
description:
  DNA-binding helix-turn-helix protein; KEGG: mmo:MMOB3450 0.00014 dam; adenine-specific DNA methyltransferase K06223; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_05756
symbol: AmpR
gene_biotype: protein_coding
description:
  LysR substrate binding domain protein; Psort location: Cytoplasmic, score: 9.97; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: PROVRUST_05757
symbol: AmpC
gene_biotype: protein_coding
description:
  Beta-lactamase; KEGG: son:SO2388 2.1e-92 beta-lactamase K01467; Psort location: Periplasmic, score: 9.44.


ensembl_gene_id: PROVRUST_05758
symbol: hemN
gene_biotype: protein_coding
description:
  Coproporphyrinogen dehydrogenase; KEGG: plu:plu0230 1.3e-202 hemN; oxygen-independent coproporphyrinogen III oxidase (coproporphyrinogenase) (coprogen oxidase) K02495; Psort location: Cytoplasmic, score: 9.97; Belongs to the anaerobic coproporphyrinogen-III oxidase family.


ensembl_gene_id: PROVRUST_05759
symbol: yihI
gene_biotype: protein_coding
description:
  Hypothetical protein; A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis. Belongs to the YihI family.


ensembl_gene_id: PROVRUST_05760
symbol: PurP
gene_biotype: protein_coding
description:
  Putative permease; KEGG: bcz:BCZK0244 2.4e-82 guanine-hypoxanthine permease; xanthine/uracil permease family protein K06901; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_05761
symbol: GltK_1
gene_biotype: protein_coding
description:
  KEGG: hpa:HPAG1_0922 1.5e-18 amino acid ABC transporter, permease protein; Psort location: CytoplasmicMembrane, score: 9.82.


ensembl_gene_id: PROVRUST_05763
symbol: YecS
gene_biotype: protein_coding
description:
  ABC transporter, permease protein; KEGG: aci:ACIAD3488 1.4e-24 putative amino acid transport protein (ABC superfamily, ATP_bind and membrane) K02028:K02029; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_05764
symbol: FliY
gene_biotype: protein_coding
description:
  KEGG: bur:Bcep18194_A4762 7.1e-83 ABC amino acid transporter, periplasmic ligand binding protein K01713; Psort location: Periplasmic, score: 10.00; Belongs to the bacterial solute-binding protein 3 family.


ensembl_gene_id: PROVRUST_05765
symbol: phoU
gene_biotype: protein_coding
description:
  Phosphate transport system regulatory protein PhoU; Part of the phosphate (Pho) regulon, which plays a key role in phosphate homeostasis. PhoU is essential for the repression of the Pho regulon at high phosphate conditions.


ensembl_gene_id: PROVRUST_05766
symbol: pstB
gene_biotype: protein_coding
description:
  Phosphate ABC transporter, ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.


ensembl_gene_id: PROVRUST_05767
symbol: pstA
gene_biotype: protein_coding
description:
  KEGG: bpm:BURPS1710b_A0449 1.1e-05 glycine betaine/L-proline ABC transporter, permease protein K02001; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_05768
symbol: pstC
gene_biotype: protein_coding
description:
  Phosphate ABC transporter, permease protein PstC; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: PROVRUST_05769
symbol: pstS
gene_biotype: protein_coding
description:
  Phosphate ABC transporter, phosphate-binding protein PstS; Part of the ABC transporter complex PstSACB involved in phosphate import; Belongs to the PstS family.


ensembl_gene_id: PROVRUST_05771
symbol: EnvZ
gene_biotype: protein_coding
description:
  ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: plu:plu0213 7.8e-148 envZ; osmolarity sensor protein K07638; Psort location: CytoplasmicMembrane, score: 9.82.


ensembl_gene_id: PROVRUST_05772
symbol: ompR
gene_biotype: protein_coding
description:
  Transcriptional regulatory protein OmpR; KEGG: bur:Bcep18194_A5728 5.1e-57 two component transcriptional regulator, winged helix family; Psort location: Cytoplasmic, score: 9.97.


ensembl_gene_id: PROVRUST_05773
symbol: greB
gene_biotype: protein_coding
description:
  Transcription elongation factor GreB; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.


ensembl_gene_id: PROVRUST_05774
symbol: YhgF
gene_biotype: protein_coding
description:
  Tex-like protein N-terminal domain protein; KEGG: bur:Bcep18194_A5099 1.1e-246 RNA binding S1; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_05777
symbol: feoB
gene_biotype: protein_coding
description:
  Ferrous iron transport protein B; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.


ensembl_gene_id: PROVRUST_05781
symbol: bioH
gene_biotype: protein_coding
description:
  Carboxylesterase BioH; The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.


ensembl_gene_id: PROVRUST_05783
symbol: yhgI
gene_biotype: protein_coding
description:
  IscR-regulated protein YhgI; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.


ensembl_gene_id: PROVRUST_05784
symbol: glpE
gene_biotype: protein_coding
description:
  Rhodanese-like protein; Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.


ensembl_gene_id: PROVRUST_05786
symbol: GlpR_2
gene_biotype: protein_coding
description:
  Transcriptional regulator, DeoR family; KEGG: cch:Cag_0060 0.0021 4-hydroxybutyrate coenzyme A transferase K01067.


ensembl_gene_id: PROVRUST_05787
symbol: GlpD_1
gene_biotype: protein_coding
description:
  FAD dependent oxidoreductase; KEGG: plu:plu0194 3.8e-235 glpD; aerobic glycerol-3-phosphate dehydrogenase GlpD K00111; Psort location: Cytoplasmic, score: 9.97; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.


ensembl_gene_id: PROVRUST_05790
symbol: YheS_1
gene_biotype: protein_coding
description:
  KEGG: reh:H16_A1931 3.5e-65 ABC-type transporter, duplicated ATPase domains:drug RA1 family; Psort location: CytoplasmicMembrane, score: 7.88.


ensembl_gene_id: PROVRUST_05792
symbol: EFB72993.1
gene_biotype: protein_coding
description:
  Hypothetical protein; KEGG: eci:UTI89_C1988 1.2e-25 yeaO; hypothetical protein K00589; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_05793
symbol: AlkA
gene_biotype: protein_coding
description:
  Base excision DNA repair protein, HhH-GPD family; KEGG: plu:plu0155 2.7e-83 unnamed protein product; some similarities with the C-terminal region of 3-methyladenine DNA glycosylase K01247; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_05794
symbol: PoxB
gene_biotype: protein_coding
description:
  Thiamine pyrophosphate enzyme, N-terminal TPP binding domain protein; KEGG: ypk:y2821 4.7e-237 poxB; pyruvate oxidase K00156; Belongs to the TPP enzyme family.


ensembl_gene_id: PROVRUST_05795
symbol: proP
gene_biotype: protein_coding
description:
  Proline porter II; KEGG: cal:orf19.4384 5.2e-05 HXT10; fructose symporter K01804; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_05796
symbol: PhrB
gene_biotype: protein_coding
description:
  FAD binding domain of DNA photolyase; KEGG: yps:YPTB2913 3.9e-162 phrB, phr; putative deoxyribodipyrimidine photolyase K01669; Belongs to the DNA photolyase family.


ensembl_gene_id: PROVRUST_05802
symbol: ParE1_1
gene_biotype: protein_coding
description:
  Toxin-antitoxin system, toxin component, RelE family; Psort location: Cytoplasmic, score: 8.96; Belongs to the RelE toxin family.


ensembl_gene_id: PROVRUST_05803
symbol: ParD1_1
gene_biotype: protein_coding
description:
  Addiction module antidote protein, CC2985 family; KEGG: msm:MSMEG_1484 0.0035 adenylate kinase K00939; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_05804
symbol: paaN
gene_biotype: protein_coding
description:
  Phenylacetic acid degradation protein paaN; KEGG: rha:RHA1_ro02864 1.2e-169 paaN; aldehyde dehydrogenase K02618; Psort location: Cytoplasmic, score: 9.26.


ensembl_gene_id: PROVRUST_05805
symbol: paaG
gene_biotype: protein_coding
description:
  phenylacetate-CoA oxygenase, PaaG subunit; KEGG: reh:H16_A3520 8.4e-112 paaA1; phenylacetic acid degradation protein A K00455; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_05809
symbol: paaK
gene_biotype: protein_coding
description:
  phenylacetate-CoA oxygenase/reductase, PaaK subunit; KEGG: reh:H16_B1359 8.5e-87 paaE2; phenylacetic acid degradation protein E,flavodoxin reductase; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_05810
symbol: EchA8_2
gene_biotype: protein_coding
description:
  enoyl-CoA hydratase/isomerase family protein; KEGG: ecj:JW1388 9.5e-72 paaF; enoyl-CoA hydratase-isomerase K01692.


ensembl_gene_id: PROVRUST_05812
symbol: PaaH
gene_biotype: protein_coding
description:
  3-hydroxy-acyl-CoA dehydrogenase; KEGG: ecj:JW1390 5.3e-110 paaH; 3-hydroxybutyryl-CoA dehydrogenase K00074.


ensembl_gene_id: PROVRUST_05814
symbol: pcaF
gene_biotype: protein_coding
description:
  Beta-ketoadipyl CoA thiolase; KEGG: ecj:JW1392 1.2e-158 paaJ; predicted beta-ketoadipyl CoA thiolase K02615; Psort location: Cytoplasmic, score: 9.26; Belongs to the thiolase-like superfamily. Thiolase family.


ensembl_gene_id: PROVRUST_05815
symbol: paaF
gene_biotype: protein_coding
description:
  phenylacetate-CoA ligase; Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).


ensembl_gene_id: PROVRUST_05817
symbol: paaY
gene_biotype: protein_coding
description:
  Phenylacetic acid degradation protein PaaY; KEGG: eci:UTI89_C0041 3.1e-57 caiE; carnitine operon protein CaiE K08279.


ensembl_gene_id: PROVRUST_05818
symbol: EmrB_2
gene_biotype: protein_coding
description:
  Drug resistance MFS transporter, drug:H+ antiporter-2 family; KEGG: sgl:SG1466 3.2e-08 dethiobiotin synthase K01935; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the major facilitator superfamily.


ensembl_gene_id: PROVRUST_05821
symbol: EFB73022.1
gene_biotype: protein_coding
description:
  Putative siderophore receptor IreA; KEGG: shn:Shewana3_3063 4.6e-06 phosphatidylglycerophosphatase K01094; Psort location: OuterMembrane, score: 9.92.


ensembl_gene_id: PROVRUST_05823
symbol: AllS_1
gene_biotype: protein_coding
description:
  KEGG: shn:Shewana3_3435 1.4e-08 transcriptional regulator, LysR family K06022; Psort location: Cytoplasmic, score: 9.26; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: PROVRUST_05828
symbol: EFB73029.1
gene_biotype: protein_coding
description:
  Inorganic anion transporter, SulP family; KEGG: aci:ACIAD3384 0.00045 putative sulfate permease K01672; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_05829
symbol: ArcC2
gene_biotype: protein_coding
description:
  Putative carbamate kinase; KEGG: ecj:JW0315 1.1e-120 yahI; predicted carbamate kinase-like protein K00926; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_05830
symbol: EFB73031.1
gene_biotype: protein_coding
description:
  Hypothetical protein; KEGG: sce:YKL192C 0.00080 ACP1; mitochondrial acyl carrier protein K00329:K00356; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_05833
symbol: EFB73034.1
gene_biotype: protein_coding
description:
  Type III secretion target, IpaC/SipC family; KEGG: cal:orf19.2410 0.0033 IMH1; involved in vesicular transport K01553.


ensembl_gene_id: PROVRUST_05834
symbol: SipB
gene_biotype: protein_coding
description:
  Hypothetical protein; KEGG: cal:orf19.4683 0.00036 MLP1; myosin-like protein involved in translocation of macromolecules between the nucleoplasm and the NPC K01553; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_05836
symbol: SpaS
gene_biotype: protein_coding
description:
  Putative surface presentation of antigens protein SpaS; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_05837
symbol: epaR
gene_biotype: protein_coding
description:
  Type III secretion apparatus protein SpaR/YscT/HrcT; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_05838
symbol: FliQ_1
gene_biotype: protein_coding
description:
  Type III secretion protein, HrpO family; KEGG: vvu:VV1_1623 0.0089 leader peptidase (prepilin peptidase) / N-methyltransferase K02654.


ensembl_gene_id: PROVRUST_05839
symbol: epaP
gene_biotype: protein_coding
description:
  Type III secretion apparatus protein, YscR/HrcR family; Psort location: CytoplasmicMembrane, score: 9.46.


ensembl_gene_id: PROVRUST_05840
symbol: EFB73041.1
gene_biotype: protein_coding
description:
  Putative type III secretion apparatus protein, YscQ/HrcQ family; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_05843
symbol: invC
gene_biotype: protein_coding
description:
  Invasion protein InvC; KEGG: bte:BTH_II0832 2.2e-120 bsaS; type III secretion system protein BsaS K03224; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_05847
symbol: InvG
gene_biotype: protein_coding
description:
  Type III secretion outer membrane pore, YscC/HrcC family; Psort location: OuterMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_05848
symbol: InvF
gene_biotype: protein_coding
description:
  Transcriptional regulator, AraC family; KEGG: bcz:BCZK2914 9.4e-05 adaA; methylphosphotriester-DNA alkyltransferase K00567.


ensembl_gene_id: PROVRUST_05856
symbol: EFB73057.1
gene_biotype: protein_coding
description:
  Transcriptional regulatory protein, C-terminal domain protein; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_05859
symbol: EFB73060.1
gene_biotype: protein_coding
description:
  Bacterial group 1 Ig-like protein; KEGG: chu:CHU_1335 6.0e-19 CHU large protein; endoglucanase-related protein, glucosyl hydrolase family 9 protein K01238; Psort location: OuterMembrane, score: 9.95.


ensembl_gene_id: PROVRUST_05860
symbol: PezA
gene_biotype: protein_coding
description:
  DNA-binding helix-turn-helix protein; KEGG: bxe:Bxe_C0924 0.00015 transcriptional regulator, XRE family with shikimate kinase activity K00891; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_05861
symbol: EFB73062.1
gene_biotype: protein_coding
description:
  Amidase, hydantoinase/carbamoylase family; KEGG: lmo:lmo0537 1.3e-69 N-carbamoyl-L-amino acid amidohydrolase; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_05862
symbol: IaaH
gene_biotype: protein_coding
description:
  Amidohydrolase; KEGG: hso:HS_1243 3.6e-127 possible peptidase, M20/M25/M40 family K01463; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_05864
symbol: codB
gene_biotype: protein_coding
description:
  Cytosine permease; KEGG: mmy:MSC_0646 0.0089 pts; PTS system, sucrose-specific IIBC component K00890; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_05866
symbol: YedW
gene_biotype: protein_coding
description:
  KEGG: rha:RHA1_ro05622 2.6e-37 response regulator (protein-glutamate methylesterase) K07669; Psort location: Cytoplasmic, score: 9.97.


ensembl_gene_id: PROVRUST_05868
symbol: msrP
gene_biotype: protein_coding
description:
  Tat pathway signal sequence domain protein; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to re [...]


ensembl_gene_id: PROVRUST_05869
symbol: msrQ
gene_biotype: protein_coding
description:
  Ferric reductase like transmembrane component; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalyti [...]


ensembl_gene_id: PROVRUST_05870
symbol: dmsD
gene_biotype: protein_coding
description:
  Twin-arginine leader-binding protein DmsD; Required for biogenesis/assembly of DMSO reductase, but not for the interaction of the DmsA signal peptide with the Tat system. May be part of a chaperone cascade complex that facilitates a folding- maturation pathway for the substrate protein.


ensembl_gene_id: PROVRUST_05871
symbol: dmsC
gene_biotype: protein_coding
description:
  DMSO reductase, anchor subunit DmsC; KEGG: eci:UTI89_C0969 2.5e-80 dmsC; anaerobic dimethyl sulfoxide reductase subunit C K07308; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_05872
symbol: DmsB_1
gene_biotype: protein_coding
description:
  KEGG: ecp:ECP_0909 2.8e-33 anaerobic dimethyl sulfoxide reductase, subunit B K07307; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_05874
symbol: dmsA
gene_biotype: protein_coding
description:
  KEGG: ecj:JW5118 0. dmsA; dimethyl sulfoxide reductase, anaerobic, subunit A K07306; Psort location: Periplasmic, score: 9.44; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: PROVRUST_05875
symbol: DcuA_1
gene_biotype: protein_coding
description:
  Transporter, anaerobic C4-dicarboxylate uptake (Dcu) family; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane; Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.


ensembl_gene_id: PROVRUST_05876
symbol: EFB73077.1
gene_biotype: protein_coding
description:
  Aspartate racemase; KEGG: eca:ECA1500 2.5e-57 probable aspartate racemase K01779; Belongs to the aspartate/glutamate racemases family.


ensembl_gene_id: PROVRUST_05877
symbol: QseD
gene_biotype: protein_coding
description:
  KEGG: shn:Shewana3_3435 4.9e-12 transcriptional regulator, LysR family K06022; Psort location: Cytoplasmic, score: 8.96; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: PROVRUST_05879
symbol: RluA_1
gene_biotype: protein_coding
description:
  Pseudouridine synthase, RluA family; KEGG: aha:AHA_1465 1.0e-90 ribosomal large subunit pseudouridine synthase A; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_05888
symbol: EFB73089.1
gene_biotype: protein_coding
description:
  DNA-binding helix-turn-helix protein; KEGG: mmo:MMOB3450 0.00018 dam; adenine-specific DNA methyltransferase K06223.


ensembl_gene_id: PROVRUST_05896
symbol: EFB73097.1
gene_biotype: protein_coding
description:
  DNA-binding helix-turn-helix protein; KEGG: sco:SCO5998 0.0021 murA2, SCBAC1C11.01c, StBAC16H6.33c; putative UDP-N-acetylglucosamine transferase K00790.


ensembl_gene_id: PROVRUST_05898
symbol: FdhF_1
gene_biotype: protein_coding
description:
  Oxidoreductase alpha (molybdopterin) subunit; KEGG: eci:UTI89_C1715 7.2e-296 ydeP; hypothetical protein YdeP K00122; Psort location: Periplasmic, score: 9.44; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: PROVRUST_05899
symbol: EFB73100.1
gene_biotype: protein_coding
description:
  DNA-binding helix-turn-helix protein; KEGG: mmo:MMOB3450 0.0010 dam; adenine-specific DNA methyltransferase K06223; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_05905
symbol: FocC_1
gene_biotype: protein_coding
description:
  Gram-negative pili assembly chaperone domain protein; Psort location: Periplasmic, score: 9.44; overlaps another CDS with the same product name.


ensembl_gene_id: PROVRUST_05907
symbol: FimD_1
gene_biotype: protein_coding
description:
  Fimbrial usher protein; KEGG: sab:SAB0215 0.00015 lytM; peptidoglycan hydrolase K08259; Psort location: OuterMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_05908
symbol: EFB73109.1
gene_biotype: protein_coding
description:
  Hypothetical protein; KEGG: chu:CHU_2225 0.00018 CHU large protein; gliding motility-related protein; possible adhesin AidA-related K01238.


ensembl_gene_id: PROVRUST_05922
symbol: prlC
gene_biotype: protein_coding
description:
  Oligopeptidase A; KEGG: eci:UTI89_C4017 8.1e-288 prlC, opdA; oligopeptidase A K01414; Psort location: Cytoplasmic, score: 9.97.


ensembl_gene_id: PROVRUST_05924
symbol: GdhA
gene_biotype: protein_coding
description:
  Glu/Leu/Phe/Val dehydrogenase, dimerization domain protein; KEGG: plu:plu0122 3.8e-210 gdhA; NADP-specific glutamate dehydrogenase (NADP-GDH) K00262; Psort location: Cytoplasmic, score: 9.97; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.


ensembl_gene_id: PROVRUST_05930
symbol: YhhW_2
gene_biotype: protein_coding
description:
  Pirin family protein; KEGG: shn:Shewana3_3385 4.5e-12 hypoxanthine phosphoribosyltransferase K00760; Belongs to the pirin family.


ensembl_gene_id: PROVRUST_05931
symbol: pckA
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.


ensembl_gene_id: PROVRUST_05932
symbol: hslO
gene_biotype: protein_coding
description:
  Chaperonin HslO; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.


ensembl_gene_id: PROVRUST_05935
symbol: nudE
gene_biotype: protein_coding
description:
  KEGG: plu:plu0096 1.1e-68 nudE; ADP compounds hydrolase nudE K08312; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_05936
symbol: MrcA_2
gene_biotype: protein_coding
description:
  KEGG: plu:plu0095 0. mrcA; penicillin-binding protein 1A (PBP-1a) (PBP1a) (penicillin-binding protein A) [includes: penicillin-insensitive transglycosylase (peptidoglycan TGase); penicillin-sensitive transpeptidase (DD-transpeptidase)] K05366.


ensembl_gene_id: PROVRUST_05940
symbol: pilQ
gene_biotype: protein_coding
description:
  Type IV pilus secretin PilQ; Psort location: OuterMembrane, score: 9.92; Belongs to the bacterial secretin family.


ensembl_gene_id: PROVRUST_05941
symbol: aroK
gene_biotype: protein_coding
description:
  Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.


ensembl_gene_id: PROVRUST_05942
symbol: aroB
gene_biotype: protein_coding
description:
  3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).


ensembl_gene_id: PROVRUST_05943
symbol: DamX_1
gene_biotype: protein_coding
description:
  Sporulation and cell division repeat protein; KEGG: mlo:mlr2363 0.0022 serine/threonine kinase K08884.


ensembl_gene_id: PROVRUST_05944
symbol: dam
gene_biotype: protein_coding
description:
  DNA adenine methylase; KEGG: plu:plu0087 1.6e-110 dam; DNA adenine methylase (deoxyadenosyl-methyltransferase) K06223.


ensembl_gene_id: PROVRUST_05945
symbol: rpe
gene_biotype: protein_coding
description:
  KEGG: ypn:YPN_3910 2.9e-102 ribulose-phosphate 3-epimerase K01783; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_05946
symbol: gph
gene_biotype: protein_coding
description:
  Phosphoglycolate phosphatase, bacterial; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.


ensembl_gene_id: PROVRUST_05947
symbol: trpS
gene_biotype: protein_coding
description:
  tryptophan--tRNA ligase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: PROVRUST_05952
symbol: YhhW_1
gene_biotype: protein_coding
description:
  Pirin family protein; KEGG: shn:Shewana3_3385 3.6e-33 hypoxanthine phosphoribosyltransferase K00760; Belongs to the pirin family.


ensembl_gene_id: PROVRUST_05953
symbol: DmlR_1
gene_biotype: protein_coding
description:
  LysR substrate binding domain protein; KEGG: shn:Shewana3_3435 0.00015 transcriptional regulator, LysR family K06022; Psort location: Cytoplasmic, score: 9.97; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: PROVRUST_05956
symbol: acsA
gene_biotype: protein_coding
description:
  acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. Enables the cell to use acetate during aerobic growth to generate energy via the TCA cycle, and biosynthetic compounds via the glyoxylate shunt. Acetylates [...]


ensembl_gene_id: PROVRUST_05958
symbol: actP
gene_biotype: protein_coding
description:
  Cation/acetate symporter ActP; Transports acetate; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: PROVRUST_05959
symbol: ProA_1
gene_biotype: protein_coding
description:
  Hypothetical protein; KEGG: rso:RS05389 2.1e-09 RSp0944; hypothetical protein; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_05962
symbol: AroH
gene_biotype: protein_coding
description:
  Class-II DAHP synthetase family protein; KEGG: atc:AGR_C_2964 4.0e-112 phospho-2-dehydro-3-deoxyheptonate aldolase K01626.


ensembl_gene_id: PROVRUST_05969
symbol: GmhB
gene_biotype: protein_coding
description:
  D,D-heptose 1,7-bisphosphate phosphatase; KEGG: plu:plu0698 1.9e-73 unnamed protein product; highly similar to unknown protein YaeD of Escherichia coli K03273; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_05970
symbol: MetI_2
gene_biotype: protein_coding
description:
  ABC transporter, permease protein; KEGG: baa:BA_0884 1.8e-45 binding-protein-dependent transport systems inner membrane component K00294; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_05971
symbol: rcsF
gene_biotype: protein_coding
description:
  Outer membrane lipoprotein; Essential component of the Rcs signaling system, which controls transcription of numerous genes. Plays a role in signal transduction from the cell surface to the histidine kinase RcsC. May detect outer membrane defects; Belongs to the RcsF family.


ensembl_gene_id: PROVRUST_05973
symbol: proS
gene_biotype: protein_coding
description:
  proline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacy [...]


ensembl_gene_id: PROVRUST_05975
symbol: Rof
gene_biotype: protein_coding
description:
  Modulator of Rho-dependent transcription termination (ROF); Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_05976
symbol: tilS
gene_biotype: protein_coding
description:
  tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.


ensembl_gene_id: PROVRUST_05978
symbol: dnaE
gene_biotype: protein_coding
description:
  KEGG: plu:plu0687 0. dnaE; DNA polymerase III alpha subunit K02337; Psort location: Cytoplasmic, score: 9.97.


ensembl_gene_id: PROVRUST_05980
symbol: lpxB
gene_biotype: protein_coding
description:
  lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: PROVRUST_05981
symbol: lpxA
gene_biotype: protein_coding
description:
  acyl-[acyl-carrier-protein]-UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: PROVRUST_05982
symbol: fabZ
gene_biotype: protein_coding
description:
  Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.


ensembl_gene_id: PROVRUST_05983
symbol: lpxD
gene_biotype: protein_coding
description:
  UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O- (hydroxytetradecanoyl)glucosamine using 3-hydroxytetradecanoyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell; Belongs to the transferase hexapeptide repeat family. LpxD subfamily.


ensembl_gene_id: PROVRUST_05984
symbol: Skp
gene_biotype: protein_coding
description:
  Outer membrane protein; KEGG: pab:PAB1179 0.00014 V-type H+-transporting ATPase subunit E K02121; Psort location: OuterMembrane, score: 9.92; Belongs to the skp family.


ensembl_gene_id: PROVRUST_05985
symbol: yaeT
gene_biotype: protein_coding
description:
  Outer membrane protein assembly complex, YaeT protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamD, the core component of the assembly machinery.


ensembl_gene_id: PROVRUST_05986
symbol: rseP
gene_biotype: protein_coding
description:
  RIP metalloprotease RseP; KEGG: plu:plu0679 4.6e-175 ecfE; protease EcfE; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_05987
symbol: cdsA
gene_biotype: protein_coding
description:
  KEGG: plu:plu0678 1.8e-109 cdsA; phosphatidate cytidylyltransferase K00981; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the CDS family.


ensembl_gene_id: PROVRUST_05988
symbol: uppS
gene_biotype: protein_coding
description:
  Di-trans,poly-cis-decaprenylcistransferase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.


ensembl_gene_id: PROVRUST_05989
symbol: dxr
gene_biotype: protein_coding
description:
  1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP).


ensembl_gene_id: PROVRUST_05990
symbol: frr
gene_biotype: protein_coding
description:
  Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.


ensembl_gene_id: PROVRUST_05992
symbol: tsf
gene_biotype: protein_coding
description:
  Translation elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.


ensembl_gene_id: PROVRUST_05993
symbol: rpsB
gene_biotype: protein_coding
description:
  Ribosomal protein S2; Psort location: Cytoplasmic, score: 8.96; Belongs to the universal ribosomal protein uS2 family.


ensembl_gene_id: PROVRUST_05995
symbol: map
gene_biotype: protein_coding
description:
  Methionine aminopeptidase, type I; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.


ensembl_gene_id: PROVRUST_05996
symbol: glnD
gene_biotype: protein_coding
description:
  protein-P-II uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.


ensembl_gene_id: PROVRUST_05997
symbol: dapD
gene_biotype: protein_coding
description:
  KEGG: sec:SC0213 2.5e-126 dapD; 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase K00674; Psort location: Cytoplasmic, score: 9.97; Belongs to the transferase hexapeptide repeat family.


ensembl_gene_id: PROVRUST_06000
symbol: TruC
gene_biotype: protein_coding
description:
  RNA pseudouridine synthase; KEGG: plu:plu0665 3.7e-93 unnamed protein product; highly similar to unknown protein YqcB of Escherichia coli K06175; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_06001
symbol: YqcC
gene_biotype: protein_coding
description:
  Hypothetical protein; KEGG: shn:Shewana3_2825 2.6e-14 dTDP-4-dehydrorhamnose 3,5-epimerase K01790; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_06004
symbol: syd
gene_biotype: protein_coding
description:
  Syd protein; Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function. Belongs to the Syd family.


ensembl_gene_id: PROVRUST_06005
symbol: queF
gene_biotype: protein_coding
description:
  Queuine synthase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).


ensembl_gene_id: PROVRUST_06006
symbol: YgdH
gene_biotype: protein_coding
description:
  Putative lysine decarboxylase; KEGG: hch:HCH_00651 3.5e-129 predicted Rossmann fold nucleotide-binding protein K00052; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_06007
symbol: xni
gene_biotype: protein_coding
description:
  5'-3' exonuclease, SAM domain protein; Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.


ensembl_gene_id: PROVRUST_06008
symbol: rlmM
gene_biotype: protein_coding
description:
  Putative RNA 2'-O-ribose methyltransferase YgdE; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.


ensembl_gene_id: PROVRUST_06010
symbol: GcvA_3
gene_biotype: protein_coding
description:
  LysR substrate binding domain protein; KEGG: shn:Shewana3_3435 1.8e-06 transcriptional regulator, LysR family K06022; Psort location: Cytoplasmic, score: 9.97; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: PROVRUST_06012
symbol: csdA
gene_biotype: protein_coding
description:
  Cysteine desulfurase, catalytic subunit CsdA; KEGG: plu:plu0651 1.0e-122 csdA; cysteine sulfinate desulfinase (CSD).


ensembl_gene_id: PROVRUST_06013
symbol: csdE
gene_biotype: protein_coding
description:
  Cysteine desulfurase, sulfur acceptor subunit CsdE; KEGG: cps:CPS_2211 7.3e-18 putative selenocysteine lyase K02426; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_06015
symbol: MltA
gene_biotype: protein_coding
description:
  MltA specific insert domain protein; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division.


ensembl_gene_id: PROVRUST_06021
symbol: argA
gene_biotype: protein_coding
description:
  KEGG: ype:YPO1022 9.3e-200 argA; amino-acid acetyltransferase K00619; Psort location: Cytoplasmic, score: 8.96; Belongs to the acetyltransferase family. ArgA subfamily.


ensembl_gene_id: PROVRUST_06023
symbol: recD
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease V, alpha subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and r [...]


ensembl_gene_id: PROVRUST_06024
symbol: recB
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease V, beta subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and re [...]


ensembl_gene_id: PROVRUST_06025
symbol: PtrA
gene_biotype: protein_coding
description:
  Peptidase, M16 family; KEGG: plu:plu0631 0. ptrA; protease III precursor (pitrilysin) K01407; Belongs to the peptidase M16 family.


ensembl_gene_id: PROVRUST_06026
symbol: recC
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease V, gamma subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and r [...]


ensembl_gene_id: PROVRUST_06031
symbol: thyA
gene_biotype: protein_coding
description:
  Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.


ensembl_gene_id: PROVRUST_06032
symbol: lgt
gene_biotype: protein_coding
description:
  Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.


ensembl_gene_id: PROVRUST_06033
symbol: ptsP
gene_biotype: protein_coding
description:
  KEGG: plu:plu0621 2.2e-287 ptsP; phosphoenolpyruvate-protein phosphotransferase PtsP (phosphotransferase system, enzyme I) (Enzyme I-Ntr) K08484; Psort location: Cytoplasmic, score: 9.26; Belongs to the PEP-utilizing enzyme family.


ensembl_gene_id: PROVRUST_06034
symbol: rppH
gene_biotype: protein_coding
description:
  Bis(5'-nucleosyl)-tetraphosphatase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily.


ensembl_gene_id: PROVRUST_06035
symbol: thiB
gene_biotype: protein_coding
description:
  Thiamine/thiamine pyrophosphate ABC transporter, thiamine/thiamine pyrophospate-binding protein; Psort location: Periplasmic, score: 9.44.


ensembl_gene_id: PROVRUST_06036
symbol: thiP
gene_biotype: protein_coding
description:
  Thiamine/thiamine pyrophosphate ABC transporter, permease protein; KEGG: cdi:DIP0495 1.0e-09 putative molybdenum ABC transport system (integral membrane and ATP-binding proteins) K02017:K02018; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_06037
symbol: thiQ
gene_biotype: protein_coding
description:
  Thiamine ABC transporter, ATP-binding protein; Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Thiamine importer (TC 3.A.1.19.1) family.


ensembl_gene_id: PROVRUST_06038
symbol: PolB
gene_biotype: protein_coding
description:
  Putative DNA polymerase II; KEGG: yps:YPTB0659 5.0e-288 polB, dinA; DNA polymerase II and and 3'--> 5' exonuclease K02336.


ensembl_gene_id: PROVRUST_06040
symbol: rapA
gene_biotype: protein_coding
description:
  ATP-dependent helicase HepA; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily.


ensembl_gene_id: PROVRUST_06041
symbol: RluA_2
gene_biotype: protein_coding
description:
  Pseudouridine synthase, RluA family; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.


ensembl_gene_id: PROVRUST_06042
symbol: djlA
gene_biotype: protein_coding
description:
  DnaJ domain protein; Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.


ensembl_gene_id: PROVRUST_06043
symbol: lptD
gene_biotype: protein_coding
description:
  Organic solvent tolerance protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.


ensembl_gene_id: PROVRUST_06044
symbol: surA
gene_biotype: protein_coding
description:
  PPIC-type PPIASE domain protein; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.


ensembl_gene_id: PROVRUST_06045
symbol: pdxA
gene_biotype: protein_coding
description:
  4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).


ensembl_gene_id: PROVRUST_06046
symbol: ksgA
gene_biotype: protein_coding
description:
  Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.


ensembl_gene_id: PROVRUST_06048
symbol: apaH
gene_biotype: protein_coding
description:
  Bis(5'-nucleosyl)-tetraphosphatase; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family.


ensembl_gene_id: PROVRUST_06049
symbol: folA
gene_biotype: protein_coding
description:
  Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.


ensembl_gene_id: PROVRUST_06051
symbol: FtsP
gene_biotype: protein_coding
description:
  Multicopper oxidase; KEGG: eci:UTI89_C3443 9.4e-152 sufI; FtsI suppressor K04753; Psort location: Periplasmic, score: 9.44.


ensembl_gene_id: PROVRUST_06052
symbol: PlsC
gene_biotype: protein_coding
description:
  Acyltransferase; KEGG: plu:plu3948 9.8e-102 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-AGP acyltransferase) (1-AGPAT) (lysophosphatidic acid acyltransferase) (LPAAT) K00655; Psort location: CytoplasmicMembrane, score: 9.46.


ensembl_gene_id: PROVRUST_06053
symbol: parC
gene_biotype: protein_coding
description:
  DNA topoisomerase IV, A subunit; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.


ensembl_gene_id: PROVRUST_06054
symbol: parE
gene_biotype: protein_coding
description:
  DNA topoisomerase IV, B subunit; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily.


ensembl_gene_id: PROVRUST_06056
symbol: cpdA
gene_biotype: protein_coding
description:
  Ser/Thr phosphatase family protein; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.


ensembl_gene_id: PROVRUST_06057
symbol: NudF
gene_biotype: protein_coding
description:
  Nudix-type nucleoside diphosphatase, YffH/AdpP family; KEGG: plu:plu3953 2.7e-74 nudF; ADP-ribose pyrophosphatase (ADP-ribose diphosphatase) (adenosine diphosphoribose pyrophosphatase) (ADPR-PPase) (ADP-ribose phosphohydrolase) K01515; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_06060
symbol: Gsp_2
gene_biotype: protein_coding
description:
  KEGG: vvy:VV2267 1.4e-125 glutathionylspermidine synthase K01917; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_06061
symbol: YgiD
gene_biotype: protein_coding
description:
  Aromatic ring-opening dioxygenase, catalytic subunit LigB; KEGG: azo:azo2868 1.7e-40 ygiD; protocatechuate 4,5-dioxygenase K04099.


ensembl_gene_id: PROVRUST_06063
symbol: ribB
gene_biotype: protein_coding
description:
  3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.


ensembl_gene_id: PROVRUST_06068
symbol: rfaE
gene_biotype: protein_coding
description:
  Bifunctional protein RfaE, domain I; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family.


ensembl_gene_id: PROVRUST_06069
symbol: glnE
gene_biotype: protein_coding
description:
  Putative bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory  [...]


ensembl_gene_id: PROVRUST_06070
symbol: EFB72785.1
gene_biotype: protein_coding
description:
  Adenylate cyclase; KEGG: aha:AHA_3770 6.1e-38 adenylate cyclase K01768; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_06071
symbol: EFB72786.1
gene_biotype: protein_coding
description:
  SH3 domain protein; KEGG: bce:BC5234 3.5e-05 N-acetylmuramoyl-L-alanine amidase K01446; Psort location: OuterMembrane, score: 9.49.


ensembl_gene_id: PROVRUST_06072
symbol: cca
gene_biotype: protein_coding
description:
  Multifunctional CCA protein; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.


ensembl_gene_id: PROVRUST_06073
symbol: folB
gene_biotype: protein_coding
description:
  Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.


ensembl_gene_id: PROVRUST_06074
symbol: plsY
gene_biotype: protein_coding
description:
  Acyl-phosphate glycerol 3-phosphate acyltransferase; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.


ensembl_gene_id: PROVRUST_06075
symbol: Aer
gene_biotype: protein_coding
description:
  PAS domain S-box protein; KEGG: azo:azo3685 8.7e-16 putative hybrid sensor and regulator protein; Psort location: CytoplasmicMembrane, score: 7.88.


ensembl_gene_id: PROVRUST_06076
symbol: tsaD
gene_biotype: protein_coding
description:
  Putative glycoprotease GCP; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.


ensembl_gene_id: PROVRUST_06077
symbol: rpsU
gene_biotype: protein_coding
description:
  Ribosomal protein S21; Psort location: Cytoplasmic, score: 8.96; Belongs to the bacterial ribosomal protein bS21 family.


ensembl_gene_id: PROVRUST_06078
symbol: dnaG
gene_biotype: protein_coding
description:
  DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.


ensembl_gene_id: PROVRUST_06079
symbol: rpoD
gene_biotype: protein_coding
description:
  RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.


ensembl_gene_id: PROVRUST_06080
symbol: Stp
gene_biotype: protein_coding
description:
  Drug resistance MFS transporter, drug:H+ antiporter-2 family; KEGG: sgl:SG1466 1.5e-12 dethiobiotin synthase K01935; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the major facilitator superfamily.


ensembl_gene_id: PROVRUST_06082
symbol: HsrA_2
gene_biotype: protein_coding
description:
  Transporter, major facilitator family protein; KEGG: ani:AN1180.2 2.7e-06 hypothetical protein K04428; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_06083
symbol: DmlR_6
gene_biotype: protein_coding
description:
  LysR substrate binding domain protein; KEGG: shn:Shewana3_3435 4.3e-10 transcriptional regulator, LysR family K06022; Psort location: Cytoplasmic, score: 9.97; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: PROVRUST_06086
symbol: MetN2
gene_biotype: protein_coding
description:
  ABC transporter, ATP-binding protein; KEGG: ava:Ava_C0015 4.3e-37 ABC transporter-like; Psort location: Cytoplasmic, score: 9.12.


ensembl_gene_id: PROVRUST_06087
symbol: GsiA_7
gene_biotype: protein_coding
description:
  KEGG: ava:Ava_B0213 1.9e-41 oligopeptide/dipeptide ABC transporter, ATP-binding protein-like K02031.


ensembl_gene_id: PROVRUST_06088
symbol: GsiD
gene_biotype: protein_coding
description:
  ABC transporter, permease protein; KEGG: mes:Meso_1141 0.0062 V-type H(+)-translocating pyrophosphatase K01507; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_06089
symbol: GsiC
gene_biotype: protein_coding
description:
  KEGG: rha:RHA1_ro09047 6.0e-31 ABC peptide transporter, permease component K02033; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_06090
symbol: AppA
gene_biotype: protein_coding
description:
  ABC transporter, substrate-binding protein, family 5; KEGG: shn:Shewana3_2650 3.0e-09 acetate kinase K00925; Psort location: Periplasmic, score: 9.44.


ensembl_gene_id: PROVRUST_06092
symbol: hypD
gene_biotype: protein_coding
description:
  Hydrogenase expression/formation protein HypD; Psort location: Cytoplasmic, score: 8.96; Belongs to the HypD family.


ensembl_gene_id: PROVRUST_06095
symbol: hypB
gene_biotype: protein_coding
description:
  Hydrogenase accessory protein HypB; KEGG: reh:H16_A1087 8.5e-16 ureG; UreA amidohydrolase (urease) regulatory and maturation protein UreG; Psort location: Cytoplasmic, score: 9.97.


ensembl_gene_id: PROVRUST_06096
symbol: hypA
gene_biotype: protein_coding
description:
  Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.


ensembl_gene_id: PROVRUST_06098
symbol: hybD
gene_biotype: protein_coding
description:
  Hydrogenase expression/formation protein; KEGG: sfx:S3241 5.1e-57 hybD; hydrogenase-2 component K08567; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_06099
symbol: hybC
gene_biotype: protein_coding
description:
  Hydrogenase-2 large chain; KEGG: ecj:JW2962 9.1e-257 hybC; hydrogenase 2, large subunit K06281; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.


ensembl_gene_id: PROVRUST_06100
symbol: HybB
gene_biotype: protein_coding
description:
  KEGG: eci:UTI89_C3417 7.6e-166 hybB; probable Ni/Fe-hydrogenase 2 B-type cytochrome subunit K00178; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_06101
symbol: FdnH_2
gene_biotype: protein_coding
description:
  Tat pathway signal sequence domain protein; KEGG: eci:UTI89_C3418 1.8e-141 hybA; hydrogenase-2 operon protein HybA precursor K00396; Psort location: Periplasmic, score: 10.00.


ensembl_gene_id: PROVRUST_06102
symbol: hybO
gene_biotype: protein_coding
description:
  Hydrogenase-2 small chain; KEGG: sbo:SBO_2866 9.9e-180 putative hydrogenase subunit K06282; Psort location: Periplasmic, score: 9.44.


ensembl_gene_id: PROVRUST_06104
symbol: hypF
gene_biotype: protein_coding
description:
  Carbamoyltransferase HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.


ensembl_gene_id: PROVRUST_06110
symbol: PapC_3
gene_biotype: protein_coding
description:
  Fimbrial usher protein; KEGG: ddi:DDB0230105 1.3e-05 putative CLK family kinase K08287; Psort location: OuterMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_06114
symbol: YdaF
gene_biotype: protein_coding
description:
  Hypothetical protein; KEGG: bcz:BCZK2820 7.1e-28 acetyltransferase, GNAT family K00680; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_06115
symbol: FadH
gene_biotype: protein_coding
description:
  Pyridine nucleotide-disulfide oxidoreductase; KEGG: plu:plu3990 3.4e-234 fadH; 2,4-dienoyl-CoA reductase [NADPH] (2,4-dienoyl coenzyme A reductase) K00219; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_06116
symbol: sstT
gene_biotype: protein_coding
description:
  Transporter, dicarboxylate/amino acid:cation Na+/H+ symporter family protein; Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system). Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: PROVRUST_06126
symbol: YqjA
gene_biotype: protein_coding
description:
  SNARE-like domain protein; KEGG: lsl:LSL_1322 2.0e-10 alkaline phosphatase K01077; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_06130
symbol: YqjF
gene_biotype: protein_coding
description:
  DoxX family protein; KEGG: lpn:lpg0671 0.00078 ndh; NADH dehydrogenase transmembrane protein K03885; Psort location: CytoplasmicMembrane, score: 9.46.


ensembl_gene_id: PROVRUST_06134
symbol: LicR
gene_biotype: protein_coding
description:
  HTH domain protein; KEGG: spi:MGAS10750_Spy1176 5.0e-36 transcription antiterminator, BglG family / PTS system, mannitol (cryptic)-specific IIA component K00890; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_06141
symbol: EFB72540.1
gene_biotype: protein_coding
description:
  Amidohydrolase, EF_0837/AHA_3915 family; KEGG: bcz:BCZK4599 1.4e-79 dihydroorotase K01465; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_06144
symbol: YccM_2
gene_biotype: protein_coding
description:
  4Fe-4S binding domain protein; KEGG: eci:UTI89_C1055 1.1e-141 yccM; putative electron transport protein YccM K00168; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_06147
symbol: DmlR_7
gene_biotype: protein_coding
description:
  LysR substrate binding domain protein; KEGG: shn:Shewana3_3435 0.00051 transcriptional regulator, LysR family K06022; Psort location: Cytoplasmic, score: 9.97; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: PROVRUST_06149
symbol: rsmI
gene_biotype: protein_coding
description:
  S-adenosylmethionine-dependent methyltransferase, YraL family; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.


ensembl_gene_id: PROVRUST_06151
symbol: EFB72549.1
gene_biotype: protein_coding
description:
  TIGR00252 family protein; KEGG: eci:UTI89_C3574 1.9e-25 yraN; hypothetical protein YraN K07460; Belongs to the UPF0102 family.


ensembl_gene_id: PROVRUST_06152
symbol: DiaA
gene_biotype: protein_coding
description:
  SIS domain protein; KEGG: plu:plu4004 1.1e-88 hypothetical protein K03271; Psort location: Cytoplasmic, score: 9.97.


ensembl_gene_id: PROVRUST_06154
symbol: mtgA
gene_biotype: protein_coding
description:
  Monofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family.


ensembl_gene_id: PROVRUST_06155
symbol: elbB
gene_biotype: protein_coding
description:
  Enhancing lycopene biosynthesis protein 2; Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate; Belongs to the peptidase C56 family.


ensembl_gene_id: PROVRUST_06156
symbol: ArcB
gene_biotype: protein_coding
description:
  PAS domain S-box protein; KEGG: plu:plu4008 0. arcB; aerobic respiration control sensor protein K07648; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_06157
symbol: GltD
gene_biotype: protein_coding
description:
  Pyridine nucleotide-disulfide oxidoreductase; KEGG: plu:plu4010 1.5e-153 gltD; glutamate synthase [NADPH] small chain (glutamate synthase beta subunit) (NADPH-GOGAT) (GLTS beta chain) K00266; Psort location: Cytoplasmic, score: 9.97.


ensembl_gene_id: PROVRUST_06159
symbol: SspA
gene_biotype: protein_coding
description:
  Glutathione S-transferase, C-terminal domain protein; KEGG: eci:UTI89_C3658 3.7e-77 sspA; stringent starvation protein A K03599; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_06162
symbol: rplM
gene_biotype: protein_coding
description:
  Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.


ensembl_gene_id: PROVRUST_06166
symbol: DegQ
gene_biotype: protein_coding
description:
  Peptidase Do; KEGG: plu:plu4018 3.7e-180 degQ; protease precursor DegQ K04772; Psort location: Periplasmic, score: 9.44; Belongs to the peptidase S1C family.


ensembl_gene_id: PROVRUST_06167
symbol: degS
gene_biotype: protein_coding
description:
  Periplasmic serine peptidase DegS; KEGG: plu:plu4022 1.3e-124 degS; protease precursor DegS K04691; Psort location: Periplasmic, score: 9.44.


ensembl_gene_id: PROVRUST_06168
symbol: murA
gene_biotype: protein_coding
description:
  UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.


ensembl_gene_id: PROVRUST_06174
symbol: MlaF
gene_biotype: protein_coding
description:
  ABC transporter, ATP-binding protein; KEGG: pen:PSEEN1099 1.5e-89 ttg2A; toluene tolerance ABC efflux transporter, ATP-binding protein K06020.


ensembl_gene_id: PROVRUST_06175
symbol: kdsD
gene_biotype: protein_coding
description:
  Arabinose 5-phosphate isomerase; KEGG: plu:plu4036 2.8e-136 putative isomerase K06041; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_06176
symbol: KdsC
gene_biotype: protein_coding
description:
  3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family.


ensembl_gene_id: PROVRUST_06177
symbol: lptC
gene_biotype: protein_coding
description:
  Hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family.


ensembl_gene_id: PROVRUST_06178
symbol: lptA
gene_biotype: protein_coding
description:
  Lipopolysaccharide transport periplasmic protein LptA; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.


ensembl_gene_id: PROVRUST_06179
symbol: LptB_1
gene_biotype: protein_coding
description:
  KEGG: pen:PSEEN1094 2.0e-87 ABC transporter, ATP-binding protein; Psort location: Cytoplasmic, score: 9.12.


ensembl_gene_id: PROVRUST_06180
symbol: rpoN
gene_biotype: protein_coding
description:
  RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.


ensembl_gene_id: PROVRUST_06181
symbol: raiA
gene_biotype: protein_coding
description:
  Ribosomal subunit interface protein; KEGG: pab:PAB0894 0.0022 leuA-3; 2-isopropylmalate synthase K01649; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_06182
symbol: ptsN
gene_biotype: protein_coding
description:
  KEGG: plu:plu4043 4.3e-60 ptsN; nitrogen regulatory IIA protein (enzyme IIA-NTR) (phosphotransferase enzyme II, A component) K02806; Psort location: Cytoplasmic, score: 9.97.


ensembl_gene_id: PROVRUST_06183
symbol: rapZ
gene_biotype: protein_coding
description:
  Hypothetical protein; Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ. When glucosamine-6- phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E. Consequently, GlmZ is inactivated and unable to activate GlmS synthesis. Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS; Belongs to the RapZ-like family. RapZ subfamily.


ensembl_gene_id: PROVRUST_06184
symbol: PtsO
gene_biotype: protein_coding
description:
  Phosphocarrier, HPr family; KEGG: aha:AHA_3919 1.1e-24 multiphosphoryl transfer protein (MTP) K00924; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_06185
symbol: rnk
gene_biotype: protein_coding
description:
  Prokaryotic transcription elongation factor, GreA/GreB domain protein; May act as an anti-Gre factor; Belongs to the Rnk family.


ensembl_gene_id: PROVRUST_06186
symbol: EFB72584.1
gene_biotype: protein_coding
description:
  Outer membrane autotransporter barrel domain protein; KEGG: pen:PSEEN3027 3.2e-77 serine protease PspB.


ensembl_gene_id: PROVRUST_06187
symbol: PmbA
gene_biotype: protein_coding
description:
  TldD/PmbA family protein; KEGG: reh:H16_A2705 3.3e-94 pmbA; microcin-processing peptidase 1; Psort location: Cytoplasmic, score: 9.97.


ensembl_gene_id: PROVRUST_06188
symbol: YjgA_2
gene_biotype: protein_coding
description:
  KEGG: nph:NP4058A 0.0036 hypothetical protein K01079; Psort location: Cytoplasmic, score: 8.96; Belongs to the UPF0307 family.


ensembl_gene_id: PROVRUST_06189
symbol: YdeN
gene_biotype: protein_coding
description:
  Hypothetical protein; KEGG: plt:Plut_2086 0.0031 lysophospholipase L2, putative K03928; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_06192
symbol: TldD
gene_biotype: protein_coding
description:
  TldD/PmbA family protein; KEGG: eci:UTI89_C3675 4.2e-204 tldD; CsrA activity inhibitor TldD K03568; Psort location: Cytoplasmic, score: 9.26.


ensembl_gene_id: PROVRUST_06195
symbol: Rng
gene_biotype: protein_coding
description:
  S1 RNA binding domain protein; KEGG: plu:plu4067 6.7e-229 cafA; ribonuclease G (RNase G) (cytoplasmic axial filament protein) K08301; Psort location: Cytoplasmic, score: 9.97.


ensembl_gene_id: PROVRUST_06196
symbol: maf
gene_biotype: protein_coding
description:
  Septum formation protein Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.


ensembl_gene_id: PROVRUST_06197
symbol: mreD
gene_biotype: protein_coding
description:
  Rod shape-determining protein MreD; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins. Belongs to the MreD family.


ensembl_gene_id: PROVRUST_06199
symbol: MreB
gene_biotype: protein_coding
description:
  Cell shape determining protein, MreB/Mrl family; KEGG: hpa:HPAG1_1318 1.4e-93 rod shape-determining protein K01529; Psort location: Cytoplasmic, score: 9.26.


ensembl_gene_id: PROVRUST_06202
symbol: aroQ
gene_biotype: protein_coding
description:
  3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.


ensembl_gene_id: PROVRUST_06203
symbol: accB
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.


ensembl_gene_id: PROVRUST_06204
symbol: accC
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.


ensembl_gene_id: PROVRUST_06206
symbol: panF
gene_biotype: protein_coding
description:
  Sodium/pantothenate symporter; KEGG: rpr:RP465 2.7e-11 phoR; alkaline phosphatase synthesis sensor protein phoR K07636; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: PROVRUST_06207
symbol: prmA
gene_biotype: protein_coding
description:
  Ribosomal protein L11 methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family.


ensembl_gene_id: PROVRUST_06208
symbol: dusB
gene_biotype: protein_coding
description:
  tRNA-dihydrouridine synthase B; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily.


ensembl_gene_id: PROVRUST_06209
symbol: fis
gene_biotype: protein_coding
description:
  DNA-binding protein Fis; Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters; Belongs to the transcriptional regulatory Fis family.


ensembl_gene_id: PROVRUST_06210
symbol: LtaA
gene_biotype: protein_coding
description:
  Beta-eliminating lyase; KEGG: gka:GK2764 5.0e-66 L-allo-threonine aldolase K01636; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_06214
symbol: Trg
gene_biotype: protein_coding
description:
  Methyl-accepting chemotaxis protein signaling domain protein; KEGG: ser:SERP2533 6.5e-06 yycG; sensory box histidine kinase YycG K07652; Psort location: CytoplasmicMembrane, score: 9.82.


ensembl_gene_id: PROVRUST_06217
symbol: Mtr_2
gene_biotype: protein_coding
description:
  Aromatic amino acid transport protein; KEGG: pfa:PFE0555w 0.0021 stearoyl-CoA desaturase (acyl-CoA desaturase, faty acid desaturase), putative K00507; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_06218
symbol: tnaA
gene_biotype: protein_coding
description:
  Putative tryptophan 2,3-dioxygenase; KEGG: plu:plu0799 2.2e-182 tnaA; tryptophanase (L-tryptophan indole-lyase) (TNase) K01667; Psort location: Cytoplasmic, score: 8.96; Belongs to the beta-eliminating lyase family.


ensembl_gene_id: PROVRUST_06223
symbol: PcaK_2
gene_biotype: protein_coding
description:
  Transporter, major facilitator family protein; KEGG: cal:orf19.3526 9.3e-10 ITR2; myo-inositol transporter K08140; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_06228
symbol: etfA
gene_biotype: protein_coding
description:
  Electron transfer flavoprotein FAD-binding domain protein; KEGG: ctc:CTC01387 1.3e-23 acyl-coA dehydrogenase K00248.


ensembl_gene_id: PROVRUST_06230
symbol: EFB72628.1
gene_biotype: protein_coding
description:
  Permease, cytosine/purine, uracil, thiamine, allantoin family; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the purine-cytosine permease (2.A.39) family.


ensembl_gene_id: PROVRUST_06231
symbol: EFB72629.1
gene_biotype: protein_coding
description:
  acyl-CoA dehydrogenase, C-terminal domain protein; KEGG: pde:Pden_0714 2.2e-104 butyryl-CoA dehydrogenase K00248.


ensembl_gene_id: PROVRUST_06232
symbol: Frc_4
gene_biotype: protein_coding
description:
  CoA-transferase family III protein; KEGG: rha:RHA1_ro04635 2.0e-101 CoA transferase K07749; Psort location: Cytoplasmic, score: 9.97; Belongs to the CoA-transferase III family.


ensembl_gene_id: PROVRUST_06236
symbol: LivF
gene_biotype: protein_coding
description:
  ABC transporter, ATP-binding protein; KEGG: pen:PSEEN1282 5.6e-83 livF; branched-chain amino acid ABC transporter, ATP-binding protein; Psort location: CytoplasmicMembrane, score: 7.88.


ensembl_gene_id: PROVRUST_06237
symbol: LptB_2
gene_biotype: protein_coding
description:
  ABC transporter, ATP-binding protein; KEGG: pen:PSEEN1283 2.8e-95 livG; branched-chain amino acid ABC transporter, ATP-binding protein.


ensembl_gene_id: PROVRUST_06238
symbol: EFB72636.1
gene_biotype: protein_coding
description:
  Branched-chain amino acid ABC transporter, permease protein; KEGG: reh:H16_A3653 6.7e-21 ABC-type transporter, ATPase and permease components; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: PROVRUST_06239
symbol: LivH
gene_biotype: protein_coding
description:
  KEGG: rha:RHA1_ro10323 4.1e-24 ABC branched chain amino acid transporter ATP-binding subunit; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: PROVRUST_06240
symbol: LivJ
gene_biotype: protein_coding
description:
  Receptor family ligand-binding protein; KEGG: ava:Ava_2791 0.00032 serine/threonine protein kinase K00903; Psort location: Periplasmic, score: 10.00.


ensembl_gene_id: PROVRUST_06241
symbol: panZ
gene_biotype: protein_coding
description:
  Hypothetical protein; Controls both the activation and catalytic activity of PanD in a coenzyme A (CoA)-dependent fashion; Belongs to the PanZ/PanM family.


ensembl_gene_id: PROVRUST_06242
symbol: EFB72640.1
gene_biotype: protein_coding
description:
  Glyoxalase family protein; KEGG: ecc:c0225 4.6e-40 yaeR; hypothetical protein YaeR K01759; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_06243
symbol: rpoH
gene_biotype: protein_coding
description:
  Alternative sigma factor RpoH; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.


ensembl_gene_id: PROVRUST_06244
symbol: FtsX
gene_biotype: protein_coding
description:
  Putative protein insertion permease FtsX; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.


ensembl_gene_id: PROVRUST_06245
symbol: ftsE
gene_biotype: protein_coding
description:
  Cell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division.


ensembl_gene_id: PROVRUST_06246
symbol: ftsY
gene_biotype: protein_coding
description:
  Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.


ensembl_gene_id: PROVRUST_06247
symbol: RsmD
gene_biotype: protein_coding
description:
  RNA methyltransferase, RsmD family; Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle; Belongs to the methyltransferase superfamily. RsmD family.


ensembl_gene_id: PROVRUST_06252
symbol: cadA
gene_biotype: protein_coding
description:
  Cadmium-exporting ATPase; KEGG: plu:plu4108 9.5e-262 zntA; lead, cadmium, zinc and mercury transporting ATPase K01532:K01534; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_06255
symbol: tusA
gene_biotype: protein_coding
description:
  Sulfur transfer protein SirA; Sulfur carrier protein involved in sulfur trafficking in the cell. Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA. Interacts with IscS and stimulates its cysteine desulfurase activity. Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation. Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin.


ensembl_gene_id: PROVRUST_06256
symbol: YhhQ
gene_biotype: protein_coding
description:
  Putative membrane protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.


ensembl_gene_id: PROVRUST_06257
symbol: glpC
gene_biotype: protein_coding
description:
  KEGG: ype:YPO3824 3.3e-181 glpC; anaerobic glycerol-3-phosphate dehydrogenase subunit C K00113; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_06258
symbol: glpB
gene_biotype: protein_coding
description:
  Glycerol-3-phosphate dehydrogenase, anaerobic, B subunit; Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor.


ensembl_gene_id: PROVRUST_06259
symbol: glpA
gene_biotype: protein_coding
description:
  KEGG: ype:YPO3826 1.4e-244 glpA; anaerobic glycerol-3-phosphate dehydrogenase subunit A K00111; Psort location: Cytoplasmic, score: 9.97; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.


ensembl_gene_id: PROVRUST_06261
symbol: GlpQ
gene_biotype: protein_coding
description:
  Glycerophosphodiester phosphodiesterase family protein; KEGG: ypa:YPA_0195 2.8e-152 glycerophosphoryl diester phosphodiesterase K01126; Psort location: Periplasmic, score: 9.44.


ensembl_gene_id: PROVRUST_06267
symbol: EFB72665.1
gene_biotype: protein_coding
description:
  Hypothetical protein; KEGG: ath:At1g55180 9.0e-08 F7A10.25; phospholipase D, putative (PLDEPSILON) K01115.


ensembl_gene_id: PROVRUST_06269
symbol: epmA
gene_biotype: protein_coding
description:
  lysine--tRNA ligase-like protein GenX; With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF- P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta-lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P; Belongs to the class-II aminoacyl-tRNA synthetase family. EpmA subfamily.


ensembl_gene_id: PROVRUST_06270
symbol: frdA
gene_biotype: protein_coding
description:
  KEGG: eca:ECA3969 1.7e-296 frdA; fumarate reductase flavoprotein subunit K00244; Psort location: Periplasmic, score: 9.44.


ensembl_gene_id: PROVRUST_06271
symbol: FrdB
gene_biotype: protein_coding
description:
  KEGG: ypm:YP_0514 5.4e-117 frdB; fumarate reductase iron-sulfur protein K00245; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.


ensembl_gene_id: PROVRUST_06272
symbol: frdC
gene_biotype: protein_coding
description:
  Fumarate reductase subunit C; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane.


ensembl_gene_id: PROVRUST_06273
symbol: frdD
gene_biotype: protein_coding
description:
  Fumarate reductase 13 kDa hydrophobic protein; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane.


ensembl_gene_id: PROVRUST_06279
symbol: SugE
gene_biotype: protein_coding
description:
  Multidrug resistance protein, SMR family; KEGG: hpa:HPAG1_1216 6.8e-05 NADH-ubiquinone oxidoreductase chain M K00329; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_06280
symbol: EamA
gene_biotype: protein_coding
description:
  Putative membrane protein; KEGG: pae:PA1977 3.1e-07 sensor protein GLPS; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_06281
symbol: cstA
gene_biotype: protein_coding
description:
  Carbon starvation protein A; KEGG: xtr:3283503 0.0023 ND6; NADH dehydrogenase subunit 6 K03884; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_06283
symbol: efp
gene_biotype: protein_coding
description:
  Translation elongation factor P; Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation; Belongs to the elongation factor P family.


ensembl_gene_id: PROVRUST_06284
symbol: KamA
gene_biotype: protein_coding
description:
  KEGG: eci:UTI89_C4744 1.6e-131 yjeK; hypothetical protein YjeK K01843; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_06287
symbol: groL
gene_biotype: protein_coding
description:
  Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.


ensembl_gene_id: PROVRUST_06288
symbol: groS
gene_biotype: protein_coding
description:
  Chaperonin GroS; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.


ensembl_gene_id: PROVRUST_06291
symbol: aspA
gene_biotype: protein_coding
description:
  KEGG: plu:plu4137 2.2e-221 aspA; aspartate ammonia-lyase (aspartase) K01744; Psort location: Cytoplasmic, score: 9.97.


ensembl_gene_id: PROVRUST_06292
symbol: dcuA
gene_biotype: protein_coding
description:
  Anaerobic C4-dicarboxylate transporter DcuA; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane; Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.


ensembl_gene_id: PROVRUST_06293
symbol: EFB72225.1
gene_biotype: protein_coding
description:
  stearoyl-CoA 9-desaturase; KEGG: cvi:CV2452 2.4e-75 probable linoleoyl-CoA desaturase K00508; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_06294
symbol: EFB72226.1
gene_biotype: protein_coding
description:
  Fatty acid hydroxylase superfamily; KEGG: mtu:Rv1814 3.8e-29 erg3; C-5 sterol desaturase K00258; Psort location: CytoplasmicMembrane, score: 10.00; overlaps another CDS with the same product name.


ensembl_gene_id: PROVRUST_06295
symbol: EFB72227.1
gene_biotype: protein_coding
description:
  Hypothetical protein; KEGG: eci:UTI89_C1633 1.5e-05 ynbD; putative enzyme YnbD K01104; Psort location: CytoplasmicMembrane, score: 10.00; overlaps another CDS with the same product name.


ensembl_gene_id: PROVRUST_06298
symbol: RffG_1
gene_biotype: protein_coding
description:
  NAD dependent epimerase/dehydratase family protein; KEGG: eci:UTI89_C0871 8.6e-71 ybjS; hypothetical protein YbjS K00067.


ensembl_gene_id: PROVRUST_06300
symbol: GlxK
gene_biotype: protein_coding
description:
  Glycerate kinase; KEGG: stt:t2336 6.6e-112 glxK; glycerate kinase K00865; Belongs to the glycerate kinase type-1 family.


ensembl_gene_id: PROVRUST_06301
symbol: EFB72233.1
gene_biotype: protein_coding
description:
  DNA-binding helix-turn-helix protein; KEGG: mmo:MMOB3450 0.0097 dam; adenine-specific DNA methyltransferase K06223.


ensembl_gene_id: PROVRUST_06305
symbol: PtsG_2
gene_biotype: protein_coding
description:
  Phosphotransferase system, EIIC; KEGG: efa:EF0028 4.8e-93 PTS system, IIBC components K02790:K02791; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_06306
symbol: PurB_2
gene_biotype: protein_coding
description:
  Lyase; KEGG: bcl:ABC2086 4.9e-178 adenylosuccinate lyase K01756; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_06307
symbol: EFB72238.1
gene_biotype: protein_coding
description:
  Outer membrane autotransporter barrel domain protein; KEGG: pen:PSEEN3028 1.9e-105 subtilisin-like serine protease; Psort location: OuterMembrane, score: 9.95.


ensembl_gene_id: PROVRUST_06309
symbol: UgpQ
gene_biotype: protein_coding
description:
  KEGG: sec:SC3482 8.5e-103 ugpQ; glycerophosphodiester phosphodiesterase, cytosolic K01126; Psort location: Cytoplasmic, score: 9.97.


ensembl_gene_id: PROVRUST_06310
symbol: ugpC
gene_biotype: protein_coding
description:
  ABC transporter, ATP-binding protein; Part of the ABC transporter complex UgpABCE involved in sn- glycerol-3-phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. sn-glycerol-3- phosphate importer (TC 3.A.1.1.3) family.


ensembl_gene_id: PROVRUST_06311
symbol: ugpE
gene_biotype: protein_coding
description:
  ABC transporter, permease protein; Part of the binding-protein-dependent transport system for sn-glycerol-3-phosphate; probably responsible for the translocation of the substrate across the membrane.


ensembl_gene_id: PROVRUST_06312
symbol: UgpA_2
gene_biotype: protein_coding
description:
  ABC transporter, permease protein; KEGG: cdi:DIP0495 0.0087 putative molybdenum ABC transport system (integral membrane and ATP-binding proteins) K02017:K02018; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_06313
symbol: MdxE
gene_biotype: protein_coding
description:
  ABC transporter, solute-binding protein; KEGG: eci:UTI89_C1581 6.0e-08 ycjN; putative ABC transporter periplasmic binding protein YcjN precursor K02027; Psort location: Periplasmic, score: 10.00.


ensembl_gene_id: PROVRUST_06316
symbol: UreR
gene_biotype: protein_coding
description:
  Transcriptional regulator, AraC family; KEGG: bha:BH0394 1.7e-08 adaA; methylphosphotriester-DNA alkyltransferase (AraC/XylS family) K00567.


ensembl_gene_id: PROVRUST_06317
symbol: CsaA
gene_biotype: protein_coding
description:
  Export-related chaperone CsaA; KEGG: ret:RHE_CH03014 4.1e-23 csaA; methionine--tRNA ligase protein; Psort location: Cytoplasmic, score: 9.97.


ensembl_gene_id: PROVRUST_06321
symbol: PduL
gene_biotype: protein_coding
description:
  Propanediol utilization protein PduL; Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.


ensembl_gene_id: PROVRUST_06323
symbol: cutD
gene_biotype: protein_coding
description:
  Glycyl-radical enzyme activating protein family protein; Catalyzes activation of the choline trimethylamine-lyase CutC under anaerobic conditions by generation of an organic free radical on a glycine residue, via an homolytic cleavage of S-adenosyl-L-methionine (SAM).


ensembl_gene_id: PROVRUST_06324
symbol: cutC-2
gene_biotype: protein_coding
description:
  Putative formate C-acetyltransferase; Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde. Belongs to the glycyl radical enzyme (GRE) family. CutC subfamily.


ensembl_gene_id: PROVRUST_06325
symbol: AdhE_2
gene_biotype: protein_coding
description:
  Alcohol dehydrogenase, iron-dependent; KEGG: eci:UTI89_C4965 1.0e-136 hypothetical protein K00001; Psort location: Cytoplasmic, score: 9.26.


ensembl_gene_id: PROVRUST_06327
symbol: AdhE_3
gene_biotype: protein_coding
description:
  Acetaldehyde dehydrogenase (acetylating); KEGG: eci:UTI89_C4967 1.6e-211 hypothetical protein K00132; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_06333
symbol: KstR2_2
gene_biotype: protein_coding
description:
  Transcriptional regulator, TetR family; KEGG: bcl:ABC2937 0.0052 NADH dehydrogenase K03885; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_06335
symbol: potD
gene_biotype: protein_coding
description:
  Spermidine/putrescine ABC transporter periplasmic substrate-binding protein; Required for the activity of the bacterial periplasmic transport system of putrescine; Belongs to the bacterial solute-binding protein PotD/PotF family.


ensembl_gene_id: PROVRUST_06336
symbol: potC
gene_biotype: protein_coding
description:
  KEGG: ava:Ava_0243 8.5e-15 molybdate ABC transporter, permease protein K02018; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_06337
symbol: potB
gene_biotype: protein_coding
description:
  KEGG: hpa:HPAG1_0451 1.8e-12 molybdenum ABC transporter ModB K06022; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_06338
symbol: potA
gene_biotype: protein_coding
description:
  Putrescine/spermidine ABC transporter ATPase protein; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.


ensembl_gene_id: PROVRUST_06339
symbol: fumB
gene_biotype: protein_coding
description:
  Fumarate hydratase class I, anaerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.


ensembl_gene_id: PROVRUST_06342
symbol: araD
gene_biotype: protein_coding
description:
  KEGG: ypm:YP_0360 5.7e-97 araD1; L-ribulose-5-phosphate 4-epimerase K01786; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_06344
symbol: LsrB
gene_biotype: protein_coding
description:
  Hypothetical protein; KEGG: msm:MSMEG_3095 3.8e-11 D-ribose-binding periplasmic protein; Psort location: Periplasmic, score: 9.44.


ensembl_gene_id: PROVRUST_06345
symbol: AraG
gene_biotype: protein_coding
description:
  KEGG: ypm:YP_0357 1.4e-205 mglA1; putative sugar ABC transporter, ATP-binding protein K02056; Psort location: CytoplasmicMembrane, score: 7.88.


ensembl_gene_id: PROVRUST_06346
symbol: RbsC_2
gene_biotype: protein_coding
description:
  Branched-chain amino acid ABC transporter, permease protein; KEGG: msm:MSMEG_4171 1.5e-43 ribose transport system permease protein RbsC; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_06347
symbol: LsrD
gene_biotype: protein_coding
description:
  Branched-chain amino acid ABC transporter, permease protein; KEGG: msm:MSMEG_3090 2.4e-34 ribose transport system permease protein RbsC; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_06348
symbol: UlaE
gene_biotype: protein_coding
description:
  KEGG: ype:YPO3333 2.9e-118 sgbU; putative hexulose-6-phosphate isomerase K03082; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_06349
symbol: Lyx
gene_biotype: protein_coding
description:
  Carbohydrate kinase, FGGY family protein; KEGG: ype:YPO3334 4.9e-171 sgbK, lyx, lyxK, xylK; putative L-xylulose kinase K00880; Belongs to the FGGY kinase family.


ensembl_gene_id: PROVRUST_06351
symbol: SoxB_2
gene_biotype: protein_coding
description:
  FAD dependent oxidoreductase; KEGG: ret:RHE_PF00356 1.8e-45 putative D-amino acid oxidase protein K00301; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_06354
symbol: FhuC
gene_biotype: protein_coding
description:
  KEGG: eca:ECA2561 3.6e-95 putative iron ABC transporter, ATP-binding protein K02013; Psort location: Cytoplasmic, score: 9.12.


ensembl_gene_id: PROVRUST_06355
symbol: FeuC
gene_biotype: protein_coding
description:
  Clp amino terminal domain protein; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: PROVRUST_06358
symbol: MalL
gene_biotype: protein_coding
description:
  Alpha amylase, catalytic domain protein; KEGG: lmf:LMOf2365_0270 1.2e-137 malL-2; oligo-1,6-glucosidase K01182; Psort location: Cytoplasmic, score: 9.26.


ensembl_gene_id: PROVRUST_06359
symbol: glgB
gene_biotype: protein_coding
description:
  1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.


ensembl_gene_id: PROVRUST_06360
symbol: glgX
gene_biotype: protein_coding
description:
  Glycogen debranching enzyme GlgX; KEGG: eca:ECA4150 1.2e-197 glgX, amyX, glyX; intracellular isoamylase K02438; Belongs to the glycosyl hydrolase 13 family.


ensembl_gene_id: PROVRUST_06361
symbol: glgC
gene_biotype: protein_coding
description:
  Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.


ensembl_gene_id: PROVRUST_06363
symbol: EFB72294.1
gene_biotype: protein_coding
description:
  Carbohydrate phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.


ensembl_gene_id: PROVRUST_06364
symbol: glgP
gene_biotype: protein_coding
description:
  Phosphorylase, glycogen/starch/alpha-glucan family; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.


ensembl_gene_id: PROVRUST_06368
symbol: EFB72299.1
gene_biotype: protein_coding
description:
  Acyltransferase; KEGG: oih:OB0869 2.3e-05 1-acyl-sn-glycerol-3-phosphate acetyltransferase K00655; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_06369
symbol: EFB72300.1
gene_biotype: protein_coding
description:
  Molybdopterin oxidoreductase Fe4S4 domain protein; KEGG: aha:AHA_2495 1.3e-60 fdhA; formate dehydrogenase, alpha subunit, selenocysteine-containing K00122.


ensembl_gene_id: PROVRUST_06370
symbol: FdhF_2
gene_biotype: protein_coding
description:
  Formate dehydrogenase, alpha subunit; KEGG: ecc:c5625 7.7e-228 fdhF; formate dehydrogenase H K00123; Psort location: Periplasmic, score: 9.44; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: PROVRUST_06371
symbol: FhlA_1
gene_biotype: protein_coding
description:
  Sigma-54 interaction domain protein; KEGG: eci:UTI89_C3094 1.3e-138 fhlA; formate hydrogenlyase transcriptional activator K01768; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_06372
symbol: HydN
gene_biotype: protein_coding
description:
  4Fe-4S binding domain protein; KEGG: eci:UTI89_C3075 1.0e-60 hydN; electron transport protein HydN K05796; Psort location: Cytoplasmic, score: 9.97.


ensembl_gene_id: PROVRUST_06375
symbol: cah
gene_biotype: protein_coding
description:
  Carbonate dehydratase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family.


ensembl_gene_id: PROVRUST_06377
symbol: HycG
gene_biotype: protein_coding
description:
  NADH ubiquinone oxidoreductase, 20 Kd subunit; KEGG: eca:ECA1239 2.4e-107 hyfI; hydrogenase-4 component I.


ensembl_gene_id: PROVRUST_06379
symbol: HyfG
gene_biotype: protein_coding
description:
  Respiratory-chain NADH dehydrogenase, 30 Kd subunit; KEGG: eca:ECA1241 2.3e-267 hyfG; hydrogenase-4 component G; Psort location: Periplasmic, score: 9.44.


ensembl_gene_id: PROVRUST_06380
symbol: HyfB_1
gene_biotype: protein_coding
description:
  KEGG: eca:ECA1242 9.7e-205 hyfF; NADH dehydrogenase subunit N; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_06381
symbol: HyfE
gene_biotype: protein_coding
description:
  NADH-ubiquinone/plastoquinone oxidoreductase chain 4L; KEGG: eca:ECA1243 1.0e-83 hyfE; hydrogenase-4 component E; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_06382
symbol: NuoL_2
gene_biotype: protein_coding
description:
  NADH-ubiquinone/plastoquinone (complex I) family protein; KEGG: eca:ECA1244 4.5e-200 hyfD; hydrogenase 4 membrane subunit; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_06383
symbol: HyfC
gene_biotype: protein_coding
description:
  NADH dehydrogenase; KEGG: eca:ECA1245 7.6e-134 hyfC; hydrogenase-4 component C; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_06384
symbol: HyfB_2
gene_biotype: protein_coding
description:
  KEGG: eca:ECA1246 4.8e-267 hyfB; NADH dehydrogenase subunit N; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_06385
symbol: HyfA
gene_biotype: protein_coding
description:
  4Fe-4S binding domain protein; KEGG: eca:ECA1247 1.1e-61 hyfA; hydrogenase-4 component A; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_06389
symbol: EFB72320.1
gene_biotype: protein_coding
description:
  Rhodanese-like protein; KEGG: msu:MS1140 5.6e-154 sseA; rhodanese-related sulfurtransferases K01010.


ensembl_gene_id: PROVRUST_06409
symbol: dcm
gene_biotype: protein_coding
description:
  KEGG: rpd:RPD_1972 2.1e-51 DNA-cytosine methyltransferase K00558; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.


ensembl_gene_id: PROVRUST_06410
symbol: EFB72341.1
gene_biotype: protein_coding
description:
  Site-specific recombinase, phage integrase family; Psort location: Cytoplasmic, score: 8.96; Belongs to the 'phage' integrase family.


ensembl_gene_id: PROVRUST_06413
symbol: AmpH
gene_biotype: protein_coding
description:
  Beta-lactamase; KEGG: eci:UTI89_C0391 1.6e-101 yaiH; penicillin-binding protein AmpH K01467; Psort location: CytoplasmicMembrane, score: 8.58.


ensembl_gene_id: PROVRUST_06415
symbol: lptF
gene_biotype: protein_coding
description:
  Lipopolysaccharide export system permease protein LptF; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_06416
symbol: pepA
gene_biotype: protein_coding
description:
  Cytosol aminopeptidase family, catalytic domain protein; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.


ensembl_gene_id: PROVRUST_06418
symbol: valS
gene_biotype: protein_coding
description:
  valine--tRNA ligase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.


ensembl_gene_id: PROVRUST_06419
symbol: YsnE
gene_biotype: protein_coding
description:
  Acetyltransferase, GNAT family; KEGG: eca:ECA0386 2.6e-53 putative acetyltransferase K03828; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_06420
symbol: rraB
gene_biotype: protein_coding
description:
  Hypothetical protein; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.


ensembl_gene_id: PROVRUST_06421
symbol: argF
gene_biotype: protein_coding
description:
  Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.


ensembl_gene_id: PROVRUST_06426
symbol: pyrB
gene_biotype: protein_coding
description:
  KEGG: ypa:YPA_3715 1.5e-137 aspartate carbamoyltransferase catalytic subunit K00609; Psort location: Cytoplasmic, score: 9.97; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.


ensembl_gene_id: PROVRUST_06427
symbol: pyrI
gene_biotype: protein_coding
description:
  Aspartate carbamoyltransferase, regulatory subunit; Involved in allosteric regulation of aspartate carbamoyltransferase.


ensembl_gene_id: PROVRUST_06429
symbol: nrdD
gene_biotype: protein_coding
description:
  KEGG: ssn:SSO_4419 0. nrdD; anaerobic ribonucleoside-triphosphate reductase K00527; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_06430
symbol: nrdG
gene_biotype: protein_coding
description:
  Anaerobic ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.


ensembl_gene_id: PROVRUST_06435
symbol: EFB72365.1
gene_biotype: protein_coding
description:
  Acetyltransferase, GNAT family; KEGG: plu:plu4504 1.5e-59 unnamed protein product; highly similar to hypothetical acetyltransferase YhbS of Escherichia coli K03824; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_06438
symbol: EFB72368.1
gene_biotype: protein_coding
description:
  Peptidase, U32 family; KEGG: eci:UTI89_C3586 1.5e-114 yhbV; hypothetical protein YhbV K01423; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_06448
symbol: YehU
gene_biotype: protein_coding
description:
  LytS/YhcK-type transmembrane receptor domain protein; KEGG: ecj:JW5353 1.3e-218 yehU; predicted sensory kinase in two-component system with YehT K07704; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_06449
symbol: YehT
gene_biotype: protein_coding
description:
  Response regulator receiver domain protein; KEGG: rru:Rru_A0376 6.5e-73 transcriptional regulator, LytR/AlgR family K07705; Psort location: Cytoplasmic, score: 9.97.


ensembl_gene_id: PROVRUST_06450
symbol: deaD
gene_biotype: protein_coding
description:
  DEAD/DEAH box helicase; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.


ensembl_gene_id: PROVRUST_06453
symbol: pnp
gene_biotype: protein_coding
description:
  Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.


ensembl_gene_id: PROVRUST_06454
symbol: rpsO
gene_biotype: protein_coding
description:
  Ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.


ensembl_gene_id: PROVRUST_06455
symbol: truB
gene_biotype: protein_coding
description:
  tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.


ensembl_gene_id: PROVRUST_06456
symbol: rbfA
gene_biotype: protein_coding
description:
  Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.


ensembl_gene_id: PROVRUST_06457
symbol: infB
gene_biotype: protein_coding
description:
  Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.


ensembl_gene_id: PROVRUST_06458
symbol: nusA
gene_biotype: protein_coding
description:
  Transcription termination factor NusA; Participates in both transcription termination and antitermination.


ensembl_gene_id: PROVRUST_06459
symbol: rimP
gene_biotype: protein_coding
description:
  Hypothetical protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.


ensembl_gene_id: PROVRUST_06462
symbol: secG
gene_biotype: protein_coding
description:
  Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.


ensembl_gene_id: PROVRUST_06464
symbol: glmM
gene_biotype: protein_coding
description:
  Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.


ensembl_gene_id: PROVRUST_06465
symbol: folP
gene_biotype: protein_coding
description:
  Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.


ensembl_gene_id: PROVRUST_06466
symbol: hflB
gene_biotype: protein_coding
description:
  Cell division protease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family.  In the central section; belongs to the AAA ATPase family.


ensembl_gene_id: PROVRUST_06467
symbol: rrmJ
gene_biotype: protein_coding
description:
  Ribosomal RNA large subunit methyltransferase J; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.


ensembl_gene_id: PROVRUST_06469
symbol: greA
gene_biotype: protein_coding
description:
  Transcription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.


ensembl_gene_id: PROVRUST_06470
symbol: dacB
gene_biotype: protein_coding
description:
  KEGG: plu:plu4539 3.7e-205 dacB; penicillin-binding protein 4 precursor (PBP-4) [includes: D-alanyl-D-alanine carboxypeptidase (DD-peptidase) (DD-carboxypeptidase); D-alanyl-D-alanine-endopeptidase (DD-endopeptidase)] K07259.


ensembl_gene_id: PROVRUST_06471
symbol: cgtA
gene_biotype: protein_coding
description:
  Obg family GTPase CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.


ensembl_gene_id: PROVRUST_06473
symbol: rplU
gene_biotype: protein_coding
description:
  Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.


ensembl_gene_id: PROVRUST_06474
symbol: IspB
gene_biotype: protein_coding
description:
  Polyprenyl synthetase; KEGG: plu:plu4543 2.7e-138 ispB; octaprenyl-diphosphate synthase (octaprenyl pyrophosphate synthetase) (OPP synthetase) K02523; Psort location: Cytoplasmic, score: 9.97.


ensembl_gene_id: PROVRUST_06476
symbol: EFB72404.1
gene_biotype: protein_coding
description:
  Hypothetical protein; KEGG: stt:t4136 0.0011 malK; maltose/maltodextrin transport ATP-binding protein K02023.


ensembl_gene_id: PROVRUST_06481
symbol: mpl
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily.


ensembl_gene_id: PROVRUST_06482
symbol: fbp
gene_biotype: protein_coding
description:
  Fructose-1,6-bisphosphatase; KEGG: plu:plu4550 1.3e-168 fbp; fructose-1,6-bisphosphatase (D-fructose-1,6-bisphosphate 1-phosphohydrolase) (FBPase) K03841; Belongs to the FBPase class 1 family.


ensembl_gene_id: PROVRUST_06483
symbol: ppa
gene_biotype: protein_coding
description:
  Inorganic diphosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.


ensembl_gene_id: PROVRUST_06485
symbol: Ddc_2
gene_biotype: protein_coding
description:
  Pyridoxal-dependent decarboxylase domain protein; KEGG: cps:CPS_1007 1.4e-16 putative decarboxylase K01580.


ensembl_gene_id: PROVRUST_06489
symbol: msrA
gene_biotype: protein_coding
description:
  Peptide-methionine (S)-S-oxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.


ensembl_gene_id: PROVRUST_06491
symbol: YtfL_2
gene_biotype: protein_coding
description:
  Hypothetical protein; KEGG: hpa:HPAG1_1423 1.2e-34 putative integral membrane protein with a TlyC-like hemolysin domain K00088; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_06494
symbol: QseC_2
gene_biotype: protein_coding
description:
  ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: eca:ECA0007 5.4e-124 qseC; two-component system sensor kinase K07645; Psort location: CytoplasmicMembrane, score: 9.82.


ensembl_gene_id: PROVRUST_06495
symbol: MprA
gene_biotype: protein_coding
description:
  KEGG: rha:RHA1_ro05622 2.5e-39 response regulator (protein-glutamate methylesterase) K07669; Psort location: Cytoplasmic, score: 9.97.


ensembl_gene_id: PROVRUST_06497
symbol: NudK
gene_biotype: protein_coding
description:
  Nudix-type nucleoside diphosphatase, YffH/AdpP family; KEGG: pfl:PFL_3331 6.3e-59 nudF; ADP-ribose pyrophosphatase K01515.


ensembl_gene_id: PROVRUST_06499
symbol: mqo
gene_biotype: protein_coding
description:
  Malate dehydrogenase (quinone); KEGG: rpa:RPA1331 2.3e-196 mqoB; malate:quinone oxidoreductase K00116; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_06500
symbol: cysQ
gene_biotype: protein_coding
description:
  3'(2'),5'-bisphosphate nucleotidase; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family.


ensembl_gene_id: PROVRUST_06501
symbol: FklB
gene_biotype: protein_coding
description:
  KEGG: plu:plu4561 1.5e-87 fklB; FKBP-type 22 kDa peptidyl-prolyl cis-trans isomerase (PPiase) (rotamase) (FKBP22) K03773; Psort location: OuterMembrane, score: 9.92.


ensembl_gene_id: PROVRUST_06505
symbol: rpsR
gene_biotype: protein_coding
description:
  Ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.


ensembl_gene_id: PROVRUST_06508
symbol: rlmB
gene_biotype: protein_coding
description:
  RNA methyltransferase, TrmH family, group 3; Specifically methylates the ribose of guanosine 2251 in 23S rRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.


ensembl_gene_id: PROVRUST_06509
symbol: rnr
gene_biotype: protein_coding
description:
  Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. Belongs to the RNR ribonuclease family. RNase R subfamily.


ensembl_gene_id: PROVRUST_06510
symbol: nsrR
gene_biotype: protein_coding
description:
  HTH-type transcriptional repressor NsrR; KEGG: ama:AM656 0.00045 aminotransferase, class V K04487; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_06511
symbol: purA
gene_biotype: protein_coding
description:
  Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.


ensembl_gene_id: PROVRUST_06516
symbol: hflX
gene_biotype: protein_coding
description:
  GTP-binding protein HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.


ensembl_gene_id: PROVRUST_06517
symbol: hfq
gene_biotype: protein_coding
description:
  RNA chaperone Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.


ensembl_gene_id: PROVRUST_06518
symbol: miaA
gene_biotype: protein_coding
description:
  tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.


ensembl_gene_id: PROVRUST_06519
symbol: mutL
gene_biotype: protein_coding
description:
  DNA mismatch repair domain protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.


ensembl_gene_id: PROVRUST_06522
symbol: queG
gene_biotype: protein_coding
description:
  Putative iron-sulfur cluster-binding protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family.


ensembl_gene_id: PROVRUST_06529
symbol: orn
gene_biotype: protein_coding
description:
  Oligoribonuclease; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family.


ensembl_gene_id: PROVRUST_06530
symbol: rsgA
gene_biotype: protein_coding
description:
  Ribosome small subunit-dependent GTPase A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.


ensembl_gene_id: PROVRUST_06531
symbol: psd
gene_biotype: protein_coding
description:
  Phosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).


ensembl_gene_id: PROVRUST_06532
symbol: KefA_3
gene_biotype: protein_coding
description:
  Transporter, small conductance mechanosensitive ion channel MscS family protein; KEGG: gga:374182 9.9e-09 ROCK2; Rho-associated, coiled-coil containing protein kinase 2 K04514; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_06534
symbol: HcpC_4
gene_biotype: protein_coding
description:
  Sel1 repeat protein; KEGG: eci:UTI89_C1133 5.9e-40 hypothetical protein; Psort location: Extracellular, score: 9.71.


ensembl_gene_id: PROVRUST_06535
symbol: Cof
gene_biotype: protein_coding
description:
  Cof-like hydrolase; KEGG: btl:BALH_4896 5.6e-19 hydrolase, haloacid dehalogenase-like family K01564; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_06536
symbol: EFB72461.1
gene_biotype: protein_coding
description:
  Hydrolase, alpha/beta domain protein; KEGG: plu:plu4619 1.2e-128 pldB; lysophospholipase L2 (lecithinase B) K01048; Psort location: CytoplasmicMembrane, score: 7.88.


ensembl_gene_id: PROVRUST_06537
symbol: recQ
gene_biotype: protein_coding
description:
  KEGG: plu:plu4620 4.2e-259 recQ; ATP-dependent DNA helicase RecQ K03654; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_06538
symbol: PldA
gene_biotype: protein_coding
description:
  Phospholipase A1; Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities. Belongs to the phospholipase A1 family.


ensembl_gene_id: PROVRUST_06539
symbol: EFB72464.1
gene_biotype: protein_coding
description:
  Hypothetical protein; KEGG: reh:H16_A1529 0.00018 phenylacetic acid degradation protein PaaI K01075; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_06541
symbol: PuuP
gene_biotype: protein_coding
description:
  Amino acid permease; KEGG: eci:UTI89_C0120 5.7e-10 aroP; aromatic amino acid transport protein AroP K03293; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_06542
symbol: NfdA
gene_biotype: protein_coding
description:
  Amidohydrolase family protein; KEGG: hma:rrnAC3411 1.2e-24 metal dependent amidohydrolase superfamily protein K01443:K01427:K01465:K01486; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_06545
symbol: PrfB_2
gene_biotype: protein_coding
description:
  KEGG: reh:H16_A1169 8.3e-15 prfB; protein chain release factor B (RF-2); Psort location: Cytoplasmic, score: 9.97.


ensembl_gene_id: PROVRUST_06546
symbol: EFB72471.1
gene_biotype: protein_coding
description:
  Oxidoreductase, 2OG-Fe(II) oxygenase family protein; KEGG: dre:406602 7.9e-13 egln3; egl nine homolog 3 (C. elegans).


ensembl_gene_id: PROVRUST_06547
symbol: EFB72472.1
gene_biotype: protein_coding
description:
  Hypothetical protein; KEGG: cpr:CPR_1545 0.0022 putative glutamate--cysteine ligase/putative amino acid ligase K01919.


ensembl_gene_id: PROVRUST_06549
symbol: YfnB
gene_biotype: protein_coding
description:
  KEGG: bur:Bcep18194_B2556 2.2e-24 HAD-superfamily hydrolase, subfamily IA, variant 1 K01560; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_06550
symbol: xerC
gene_biotype: protein_coding
description:
  Tyrosine recombinase XerC; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerD binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerC specifically exchanges t [...]


ensembl_gene_id: PROVRUST_06551
symbol: EFB72476.1
gene_biotype: protein_coding
description:
  Hypothetical protein; KEGG: azo:azo0595 1.7e-07 3',5'-cyclic-nucleotide phosphodiesterase K01120; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_06552
symbol: dapF
gene_biotype: protein_coding
description:
  Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.


ensembl_gene_id: PROVRUST_06554
symbol: cyaY
gene_biotype: protein_coding
description:
  Iron donor protein CyaY; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.


ensembl_gene_id: PROVRUST_06555
symbol: cyaA
gene_biotype: protein_coding
description:
  Adenylate cyclase, class I; KEGG: plu:plu4643 0. cyaA; adenylate cyclase (ATP pyrophosphate-lyase) (adenylyl cyclase) K05851; Psort location: Cytoplasmic, score: 9.97; Belongs to the adenylyl cyclase class-1 family.


ensembl_gene_id: PROVRUST_06557
symbol: hemC
gene_biotype: protein_coding
description:
  Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.


ensembl_gene_id: PROVRUST_06558
symbol: hemD
gene_biotype: protein_coding
description:
  uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.


ensembl_gene_id: PROVRUST_06559
symbol: HemX
gene_biotype: protein_coding
description:
  HemX; KEGG: plu:plu4646 5.3e-110 hemX; uroporphyrin-III C-methyltransferase (urogen III methylase) K02496.


ensembl_gene_id: PROVRUST_06568
symbol: YifK
gene_biotype: protein_coding
description:
  Amino acid permease; KEGG: eci:UTI89_C0120 2.2e-95 aroP; aromatic amino acid transport protein AroP K03293; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_06569
symbol: wecG
gene_biotype: protein_coding
description:
  Glycosyltransferase, WecB/TagA/CpsF family; Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA (Lipid II), the second lipid-linked intermediate involved in enterobacterial common antigen (ECA) synthesis.


ensembl_gene_id: PROVRUST_06570
symbol: wzyE
gene_biotype: protein_coding
description:
  ECA biosynthesis protein WzyE; Probably involved in the polymerization of enterobacterial common antigen (ECA) trisaccharide repeat units; Belongs to the WzyE family.


ensembl_gene_id: PROVRUST_06571
symbol: wecF
gene_biotype: protein_coding
description:
  TDP-Fuc4NAc:lipid II Fuc4Nac transferase; Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis; Belongs to the glycosyltransferase 56 family.


ensembl_gene_id: PROVRUST_06572
symbol: wzxE
gene_biotype: protein_coding
description:
  Polysaccharide biosynthesis protein; Mediates the transbilayer movement of Und-PP-GlcNAc-ManNAcA- Fuc4NAc (lipid III) from the inner to the outer leaflet of the cytoplasmic membrane during the assembly of enterobacterial common antigen (ECA); Belongs to the polysaccharide transport (PST) (TC 2.A.66.2) family.


ensembl_gene_id: PROVRUST_06573
symbol: wecE
gene_biotype: protein_coding
description:
  dTDP-4-amino-4,6-dideoxy-D-glucose transaminase; Catalyzes the synthesis of dTDP-4-amino-4,6-dideoxy-D- galactose (dTDP-Fuc4N) from dTDP-4-keto-6-deoxy-D-glucose (dTDP-D- Glc4O) and L-glutamate; Belongs to the DegT/DnrJ/EryC1 family.


ensembl_gene_id: PROVRUST_06574
symbol: wecD
gene_biotype: protein_coding
description:
  TDP-D-fucosamine acetyltransferase; Catalyzes the acetylation of dTDP-fucosamine (dTDP-4-amino- 4,6-dideoxy-D-galactose) to dTDP-Fuc4NAc, which is utilized in the biosynthesis of the enterobacterial common antigen (ECA). Belongs to the WecD family.


ensembl_gene_id: PROVRUST_06575
symbol: rfbA
gene_biotype: protein_coding
description:
  Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.


ensembl_gene_id: PROVRUST_06576
symbol: rfbB
gene_biotype: protein_coding
description:
  KEGG: ypm:YP_3183 1.8e-164 rffG; dTDP-glucose 4,6-dehydratase K01710; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.


ensembl_gene_id: PROVRUST_06577
symbol: wecC
gene_biotype: protein_coding
description:
  Nucleotide sugar dehydrogenase; Catalyzes the four-electron oxidation of UDP-N-acetyl-D- mannosamine (UDP-ManNAc), reducing NAD(+) and releasing UDP-N- acetylmannosaminuronic acid (UDP-ManNAcA); Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. WecC subfamily.


ensembl_gene_id: PROVRUST_06578
symbol: wecB
gene_biotype: protein_coding
description:
  UDP-N-acetylglucosamine 2-epimerase; Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP- N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues.


ensembl_gene_id: PROVRUST_06579
symbol: wzzE
gene_biotype: protein_coding
description:
  Chain length determinant protein; Modulates the polysaccharide chain length of enterobacterial common antigen (ECA); Belongs to the WzzB/Cld/Rol family.


ensembl_gene_id: PROVRUST_06580
symbol: wecA
gene_biotype: protein_coding
description:
  Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase; Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP-C55).


ensembl_gene_id: PROVRUST_06581
symbol: rho
gene_biotype: protein_coding
description:
  Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.


ensembl_gene_id: PROVRUST_06583
symbol: trxA
gene_biotype: protein_coding
description:
  Thioredoxin; KEGG: eci:UTI89_C4335 1.3e-44 trxA; thioredoxin 1 K03671; Psort location: Cytoplasmic, score: 9.26; Belongs to the thioredoxin family.


ensembl_gene_id: PROVRUST_06584
symbol: rhlB
gene_biotype: protein_coding
description:
  DEAD/DEAH box helicase; DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. Belongs to the DEAD box helicase family. RhlB subfamily.


ensembl_gene_id: PROVRUST_06585
symbol: gppA
gene_biotype: protein_coding
description:
  Putative exopolyphosphatase; Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities.


ensembl_gene_id: PROVRUST_06586
symbol: rep
gene_biotype: protein_coding
description:
  ATP-dependent DNA helicase Rep; Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.


ensembl_gene_id: PROVRUST_06587
symbol: ilvC
gene_biotype: protein_coding
description:
  Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.


ensembl_gene_id: PROVRUST_06588
symbol: HcaR_2
gene_biotype: protein_coding
description:
  LysR substrate binding domain protein; KEGG: shn:Shewana3_3435 2.8e-11 transcriptional regulator, LysR family K06022; Psort location: Cytoplasmic, score: 9.97; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: PROVRUST_06589
symbol: ilvA
gene_biotype: protein_coding
description:
  Threonine ammonia-lyase, biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.


ensembl_gene_id: PROVRUST_06590
symbol: ilvD
gene_biotype: protein_coding
description:
  KEGG: ecs:ECs4705 4.0e-286 dihydroxyacid dehydratase K01687; Psort location: Cytoplasmic, score: 8.96; Belongs to the IlvD/Edd family.


ensembl_gene_id: PROVRUST_06591
symbol: ilvE
gene_biotype: protein_coding
description:
  Branched-chain-amino-acid transaminase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: PROVRUST_06592
symbol: IlvM
gene_biotype: protein_coding
description:
  Hypothetical protein; KEGG: plu:plu4684 5.7e-26 ilvM; acetolactate synthase isozyme II small subunit (AHAS-II) (acetohydroxy-acid synthase II small subunit) (ALS-II) K01653; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_06593
symbol: ilvB
gene_biotype: protein_coding
description:
  Acetolactate synthase, large subunit, biosynthetic type; KEGG: stm:STM3901 3.4e-225 ilvG; acetolactate synthase large subunit K01652; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_06596
symbol: ComM
gene_biotype: protein_coding
description:
  Mg chelatase-like protein; KEGG: eci:UTI89_C4322 7.7e-157 yifB; putative 2-component regulator K07391; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_06598
symbol: hdfR
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon.


ensembl_gene_id: PROVRUST_06602
symbol: hutI
gene_biotype: protein_coding
description:
  Imidazolonepropionase; KEGG: plu:plu3197 1.9e-114 hutI; imidazolonepropionase (imidazolone-5-propionate hydrolase) K01468.


ensembl_gene_id: PROVRUST_06605
symbol: fadJ
gene_biotype: protein_coding
description:
  Fatty oxidation complex, alpha subunit FadJ; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities. Belongs to the enoyl-CoA hydratase/isomerase family.  In the central section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.


ensembl_gene_id: PROVRUST_06606
symbol: fadI
gene_biotype: protein_coding
description:
  acetyl-CoA C-acyltransferase FadI; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.


ensembl_gene_id: PROVRUST_06608
symbol: FadL
gene_biotype: protein_coding
description:
  Outer membrane protein transport protein, Ompp1/FadL/TodX family; Psort location: OuterMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_06613
symbol: EFB72213.1
gene_biotype: protein_coding
description:
  Hypothetical protein; KEGG: rco:RC1336 0.0031 dnaX; DNA polymerase III gamma and tau subunit K02343.


ensembl_gene_id: PROVRUST_06614
symbol: YbiR
gene_biotype: protein_coding
description:
  Citrate transporter; KEGG: ecj:JW3469 5.5e-17 arsB; arsenite/antimonite transporter K03893; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_06616
symbol: EFB72216.1
gene_biotype: protein_coding
description:
  Alkylhydroperoxidase domain protein, Avi_7169 family; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.


ensembl_gene_id: PROVRUST_06618
symbol: metN
gene_biotype: protein_coding
description:
  ABC transporter, ATP-binding protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.


ensembl_gene_id: PROVRUST_06619
symbol: MetI_1
gene_biotype: protein_coding
description:
  ABC transporter, permease protein; KEGG: baa:BA_0884 2.9e-47 binding-protein-dependent transport systems inner membrane component K00294; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_06623
symbol: EFB72172.1
gene_biotype: protein_coding
description:
  DNA-binding helix-turn-helix protein; KEGG: rfr:Rfer_0219 9.5e-06 transcriptional regulator, XRE family with shikimate kinase activity K00891.


ensembl_gene_id: PROVRUST_06633
symbol: gltX
gene_biotype: protein_coding
description:
  glutamate--tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).


ensembl_gene_id: PROVRUST_06636
symbol: Puo
gene_biotype: protein_coding
description:
  KEGG: ath:At5g13700 2.6e-37 MSH12.17; polyamine oxidase, putative K00308; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_06637
symbol: EFB72177.1
gene_biotype: protein_coding
description:
  Hypothetical protein; KEGG: cta:CTA_0585 0.00043 dnaQ_2; DNA polymerase III, epsilon chain K02342; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_06640
symbol: ligA-2
gene_biotype: protein_coding
description:
  DNA ligase (NAD+); DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily.


ensembl_gene_id: PROVRUST_06641
symbol: zipA
gene_biotype: protein_coding
description:
  Cell division protein ZipA; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.


ensembl_gene_id: PROVRUST_06642
symbol: cysZ
gene_biotype: protein_coding
description:
  Putative sulfate transport protein CysZ; High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway; Belongs to the CysZ family.


ensembl_gene_id: PROVRUST_06643
symbol: cysK
gene_biotype: protein_coding
description:
  Cysteine synthase A; KEGG: sty:STY2666 3.5e-136 cysK; cysteine synthase A K01738; Belongs to the cysteine synthase/cystathionine beta- synthase family.


ensembl_gene_id: PROVRUST_06644
symbol: ptsH
gene_biotype: protein_coding
description:
  Phosphocarrier protein HPr; KEGG: bci:BCI_0069 3.3e-30 ptsH; phosphocarrier protein HPr K00890; Psort location: Cytoplasmic, score: 9.97.


ensembl_gene_id: PROVRUST_06645
symbol: ptsP-2
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).


ensembl_gene_id: PROVRUST_06646
symbol: crr
gene_biotype: protein_coding
description:
  KEGG: eca:ECA0891 1.3e-76 crr, gsr, iex, tgs, treD; PTS system, glucose-specific IIa component K02777; Psort location: Cytoplasmic, score: 9.97.


ensembl_gene_id: PROVRUST_06647
symbol: cysM
gene_biotype: protein_coding
description:
  Cysteine synthase B; KEGG: plu:plu1391 7.0e-124 cysM; cysteine synthase B (O-acetylserine sulfhydrolase B) K01738; Belongs to the cysteine synthase/cystathionine beta- synthase family.


ensembl_gene_id: PROVRUST_06648
symbol: cysA
gene_biotype: protein_coding
description:
  Sulfate ABC transporter, ATP-binding protein; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system.


ensembl_gene_id: PROVRUST_06649
symbol: cysW
gene_biotype: protein_coding
description:
  Sulfate ABC transporter, permease protein CysW; KEGG: pac:PPA0505 1.1e-22 ABC transporter, putative molybdenum transport system K02017:K02018; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_06650
symbol: cysT
gene_biotype: protein_coding
description:
  Sulfate ABC transporter, permease protein CysT; Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: PROVRUST_06653
symbol: YfeX
gene_biotype: protein_coding
description:
  Dyp-type peroxidase family protein; KEGG: reh:H16_B0946 6.0e-47 predicted iron-dependent peroxidase K00430; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_06655
symbol: YpeA_2
gene_biotype: protein_coding
description:
  Acetyltransferase, GNAT family; KEGG: eci:UTI89_C2767 2.1e-42 ypeA; hypothetical protein YpeA K00680; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_06656
symbol: hemF
gene_biotype: protein_coding
description:
  Coproporphyrinogen III oxidase, aerobic; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX.


ensembl_gene_id: PROVRUST_06658
symbol: RluF
gene_biotype: protein_coding
description:
  Pseudouridylate synthase; KEGG: spt:SPA4031 1.2e-119 yjbC; putative pseudouridine synthase K06182; Belongs to the pseudouridine synthase RsuA family.


ensembl_gene_id: PROVRUST_06659
symbol: der
gene_biotype: protein_coding
description:
  Ribosome biogenesis GTPase Der; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.


ensembl_gene_id: PROVRUST_06660
symbol: yfgL
gene_biotype: protein_coding
description:
  Outer membrane assembly lipoprotein YfgL; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: PROVRUST_06663
symbol: ispG
gene_biotype: protein_coding
description:
  4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family.


ensembl_gene_id: PROVRUST_06664
symbol: RodZ
gene_biotype: protein_coding
description:
  Putative cytoskeleton protein RodZ; Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis. Belongs to the RodZ family.


ensembl_gene_id: PROVRUST_06665
symbol: rlmN
gene_biotype: protein_coding
description:
  23S rRNA m2A2503 methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family.


ensembl_gene_id: PROVRUST_06666
symbol: ndk
gene_biotype: protein_coding
description:
  Putative nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.


ensembl_gene_id: PROVRUST_06668
symbol: pbpC
gene_biotype: protein_coding
description:
  Penicillin-binding protein 1C; KEGG: plu:plu1371 1.8e-299 pbpC; penicillin-binding protein 1C (PBP-1C) K05367.


ensembl_gene_id: PROVRUST_06672
symbol: PepB
gene_biotype: protein_coding
description:
  Cytosol aminopeptidase family, catalytic domain protein; Probably plays an important role in intracellular peptide degradation.


ensembl_gene_id: PROVRUST_06674
symbol: fdx
gene_biotype: protein_coding
description:
  Ferredoxin, 2Fe-2S type, ISC system; KEGG: eci:UTI89_C2847 3.9e-50 fdx; ferredoxin, 2Fe-2S K04755; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_06675
symbol: hscA
gene_biotype: protein_coding
description:
  Fe-S protein assembly chaperone HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. Involved in the maturation of IscU.


ensembl_gene_id: PROVRUST_06676
symbol: hscB
gene_biotype: protein_coding
description:
  Fe-S protein assembly co-chaperone HscB; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family.


ensembl_gene_id: PROVRUST_06677
symbol: iscA
gene_biotype: protein_coding
description:
  Iron-sulfur cluster assembly protein IscA; Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system TrxA/TrxB.


ensembl_gene_id: PROVRUST_06678
symbol: iscU
gene_biotype: protein_coding
description:
  FeS cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.


ensembl_gene_id: PROVRUST_06679
symbol: iscS
gene_biotype: protein_coding
description:
  Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.


ensembl_gene_id: PROVRUST_06680
symbol: iscR
gene_biotype: protein_coding
description:
  Iron-sulfur cluster assembly transcription factor IscR; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.


ensembl_gene_id: PROVRUST_06681
symbol: trmJ
gene_biotype: protein_coding
description:
  RNA methyltransferase, TrmH family, group 1; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.


ensembl_gene_id: PROVRUST_06682
symbol: SuhB
gene_biotype: protein_coding
description:
  KEGG: eca:ECA3240 1.5e-112 suhB, ssyA; inositol-1-monophosphatase K01092; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_06683
symbol: HcaT
gene_biotype: protein_coding
description:
  Transporter, major facilitator family protein; KEGG: eci:UTI89_C3355 3.7e-05 nupG; transport of nucleosides, permease protein K03289; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_06684
symbol: glyA
gene_biotype: protein_coding
description:
  Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.


ensembl_gene_id: PROVRUST_06685
symbol: hmp
gene_biotype: protein_coding
description:
  Flavohemoprotein; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress; Belongs to the globin family. Two-domain flavohemoproteins subfamily.


ensembl_gene_id: PROVRUST_06686
symbol: GlnB
gene_biotype: protein_coding
description:
  Nitrogen regulatory protein P-II; Psort location: Cytoplasmic, score: 8.96; Belongs to the P(II) protein family.


ensembl_gene_id: PROVRUST_06687
symbol: nadE
gene_biotype: protein_coding
description:
  NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.


ensembl_gene_id: PROVRUST_06688
symbol: QseF
gene_biotype: protein_coding
description:
  Sigma-54 interaction domain protein; KEGG: eci:UTI89_C2502 3.8e-84 atoC; acetoacetate metabolism regulatory protein AtoC K07714; Psort location: Cytoplasmic, score: 9.26.


ensembl_gene_id: PROVRUST_06690
symbol: GlrK
gene_biotype: protein_coding
description:
  ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: plu:plu3313 7.7e-173 unnamed protein product; highly similar to putative sensor-like histidine kinase (two-component sensor protein kinase) YfhK of Escherichia coli K07711; Psort location: CytoplasmicMembrane, score: 9.82.


ensembl_gene_id: PROVRUST_06693
symbol: TcmN
gene_biotype: protein_coding
description:
  O-methyltransferase; KEGG: bja:blr7665 1.2e-30 putative methyltransferase K00599; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_06694
symbol: UhpA_1
gene_biotype: protein_coding
description:
  Response regulator receiver domain protein; KEGG: eci:UTI89_C1417 6.3e-27 narL; NarL transcriptional dual regulator K07684; Psort location: Cytoplasmic, score: 9.97.


ensembl_gene_id: PROVRUST_06695
symbol: DegS_1
gene_biotype: protein_coding
description:
  Histidine kinase; KEGG: plu:plu0814 3.2e-174 uhpB; two-component sensor histidine kinase UhpB, phosphorylates UhpA K07675; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_06696
symbol: UhpC_2
gene_biotype: protein_coding
description:
  Transporter, major facilitator family protein; KEGG: dre:30298 0.0034 jak2b; Janus kinase 2b K04447; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_06698
symbol: PotB_1
gene_biotype: protein_coding
description:
  ABC transporter, permease protein; KEGG: cdi:DIP0495 2.0e-14 putative molybdenum ABC transport system (integral membrane and ATP-binding proteins) K02017:K02018; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_06699
symbol: fbpC
gene_biotype: protein_coding
description:
  ABC transporter, ATP-binding protein; Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import. Responsible for energy coupling to the transport system.


ensembl_gene_id: PROVRUST_06700
symbol: YeaN
gene_biotype: protein_coding
description:
  Transporter, major facilitator family protein; KEGG: shn:Shewana3_1692 3.9e-06 Xaa-His dipeptidase K01270; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_06701
symbol: GuaD
gene_biotype: protein_coding
description:
  Cytidine and deoxycytidylate deaminase zinc-binding region; KEGG: reh:H16_B0797 6.3e-27 cytosine deaminase-related enzyme K01493.


ensembl_gene_id: PROVRUST_06703
symbol: purL
gene_biotype: protein_coding
description:
  Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.


ensembl_gene_id: PROVRUST_06704
symbol: mltF
gene_biotype: protein_coding
description:
  Transglycosylase SLT domain protein; Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.


ensembl_gene_id: PROVRUST_06705
symbol: tadA
gene_biotype: protein_coding
description:
  Cytidine and deoxycytidylate deaminase zinc-binding region; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.


ensembl_gene_id: PROVRUST_06710
symbol: EFB71956.1
gene_biotype: protein_coding
description:
  Glycosyltransferase, group 2 family protein; KEGG: lsl:LSL_0696 3.6e-24 rfaG; glycosyltransferase K00754.


ensembl_gene_id: PROVRUST_06731
symbol: EFB71977.1
gene_biotype: protein_coding
description:
  Hypothetical protein; KEGG: mav:MAV_3172 0.00021 prolipoprotein diacylglyceryl transferase K00785; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_06742
symbol: EFB71988.1
gene_biotype: protein_coding
description:
  KEGG: ece:Z2060 3.6e-120 putative DNA adenine methyltransferase encoded by prophage CP-933O K07319; Belongs to the N(4)/N(6)-methyltransferase family.


ensembl_gene_id: PROVRUST_06754
symbol: EFB72000.1
gene_biotype: protein_coding
description:
  IstB-like ATP-binding protein; KEGG: spi:MGAS10750_Spy1680 2.7e-11 replicative DNA helicase K01529; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_06758
symbol: EFB72004.1
gene_biotype: protein_coding
description:
  Putative regulatory protein cro; KEGG: spa:M6_Spy1160 0.00054 type II restriction-modification system methylation subunit K00558.


ensembl_gene_id: PROVRUST_06760
symbol: EFB72006.1
gene_biotype: protein_coding
description:
  Type I restriction enzyme HsdR protein N-terminal domain protein; Psort location: CytoplasmicMembrane, score: 9.96.


ensembl_gene_id: PROVRUST_06762
symbol: EFB72008.1
gene_biotype: protein_coding
description:
  Hypothetical protein; KEGG: eci:UTI89_C1459 1.1e-10 exoO; putative exonuclease VIII, ds DNA exonuclease encoded by prophage CP-933O K01146.


ensembl_gene_id: PROVRUST_06773
symbol: acpS
gene_biotype: protein_coding
description:
  Holo-[acyl-carrier-protein] synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.


ensembl_gene_id: PROVRUST_06774
symbol: pdxJ
gene_biotype: protein_coding
description:
  Pyridoxine 5'-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.


ensembl_gene_id: PROVRUST_06776
symbol: era
gene_biotype: protein_coding
description:
  Ribosome biogenesis GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.


ensembl_gene_id: PROVRUST_06777
symbol: rnc
gene_biotype: protein_coding
description:
  Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.


ensembl_gene_id: PROVRUST_06778
symbol: lepB
gene_biotype: protein_coding
description:
  Signal peptidase I; KEGG: plu:plu3341 3.1e-114 lepB; signal peptidase I (SPase I) (leader peptidase I) K03100; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the peptidase S26 family.


ensembl_gene_id: PROVRUST_06779
symbol: lepA
gene_biotype: protein_coding
description:
  GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.


ensembl_gene_id: PROVRUST_06782
symbol: RseA
gene_biotype: protein_coding
description:
  Anti sigma-E protein RseA domain protein; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic pro [...]


ensembl_gene_id: PROVRUST_06783
symbol: rpoE
gene_biotype: protein_coding
description:
  KEGG: reh:H16_A2563 4.9e-59 rpoE1; DNA-directed RNA polymerase sigma subunit (RpoE,sigma24) K00960; Psort location: Cytoplasmic, score: 8.96; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: PROVRUST_06785
symbol: YfiC
gene_biotype: protein_coding
description:
  Methyltransferase domain protein; Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).


ensembl_gene_id: PROVRUST_06787
symbol: hutG
gene_biotype: protein_coding
description:
  Formimidoylglutamase; Catalyzes the conversion of N-formimidoyl-L-glutamate to L- glutamate and formamide; Belongs to the arginase family.


ensembl_gene_id: PROVRUST_06789
symbol: SrmB
gene_biotype: protein_coding
description:
  DEAD/DEAH box helicase; KEGG: plu:plu3349 5.2e-174 srmB; ATP-dependent RNA helicase K05590; Psort location: Cytoplasmic, score: 8.96; Belongs to the DEAD box helicase family.


ensembl_gene_id: PROVRUST_06791
symbol: grcA
gene_biotype: protein_coding
description:
  Glycine radical domain protein; Acts as a radical domain for damaged PFL and possibly other radical proteins.


ensembl_gene_id: PROVRUST_06792
symbol: ung
gene_biotype: protein_coding
description:
  uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.


ensembl_gene_id: PROVRUST_06793
symbol: grpE
gene_biotype: protein_coding
description:
  Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...]


ensembl_gene_id: PROVRUST_06794
symbol: nadK
gene_biotype: protein_coding
description:
  NAD(+)/NADH kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.


ensembl_gene_id: PROVRUST_06796
symbol: bamE
gene_biotype: protein_coding
description:
  SmpA / OmlA family protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: PROVRUST_06799
symbol: smpB
gene_biotype: protein_coding
description:
  SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]


ensembl_gene_id: PROVRUST_06803
symbol: EFB72048.1
gene_biotype: protein_coding
description:
  DEAD/DEAH box helicase; KEGG: pfu:PF0677 2.8e-13 helicase K03726; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_06808
symbol: EFB72053.1
gene_biotype: protein_coding
description:
  Hypothetical protein; KEGG: eci:UTI89_C5113 0.0029 putative endopeptidase protein Rz of prophage CP-933K K01423.


ensembl_gene_id: PROVRUST_06814
symbol: EFB72059.1
gene_biotype: protein_coding
description:
  Hypothetical protein; KEGG: xac:XAC2899 2.3e-61 type I restriction-modification system specificity determinant K01154.


ensembl_gene_id: PROVRUST_06820
symbol: EFB72065.1
gene_biotype: protein_coding
description:
  Sel1 repeat protein; KEGG: cch:Cag_1938 3.4e-44 Sel1-like repeat; Psort location: Extracellular, score: 9.71.


ensembl_gene_id: PROVRUST_06838
symbol: EFB72083.1
gene_biotype: protein_coding
description:
  NAD dependent epimerase/dehydratase family protein; KEGG: nph:NP2406A 5.7e-14 nolA_1; NADH dehydrogenase 32K chain homolog K00329:K00356; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_06839
symbol: EFB72084.1
gene_biotype: protein_coding
description:
  Oxidoreductase, zinc-binding dehydrogenase family protein; KEGG: stt:t1499 5.1e-121 putative NADP-dependent oxidoreductase; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_06840
symbol: EFB72085.1
gene_biotype: protein_coding
description:
  Alcohol dehydrogenase, iron-dependent; KEGG: eco:b3011 7.8e-132 yqhD; putative alcohol dehydrogenase K08325; Psort location: Cytoplasmic, score: 9.26.


ensembl_gene_id: PROVRUST_06841
symbol: EFB72086.1
gene_biotype: protein_coding
description:
  Peroxiredoxin, Ohr subfamily; KEGG: reh:H16_A1791 6.5e-18 predicted redox protein, regulator of disulfide bond formation K01768; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_06842
symbol: EFB72087.1
gene_biotype: protein_coding
description:
  Aldehyde dehydrogenase (NAD) family protein; KEGG: bja:bll3998 4.0e-192 probable succinate-semialdehyde dehydrogenase [NADP+] K00135; Psort location: Cytoplasmic, score: 9.26.


ensembl_gene_id: PROVRUST_06843
symbol: EFB72088.1
gene_biotype: protein_coding
description:
  Putative phage tail component domain protein; KEGG: pha:PSHAa2447 7.0e-147 nemA; N-ethylmaleimide reductase, FMN-linked.


ensembl_gene_id: PROVRUST_06846
symbol: EFB72091.1
gene_biotype: protein_coding
description:
  KEGG: gbe:GbCGDNIH1_1022 3.4e-35 aldehyde dehydrogenase K00128; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_06849
symbol: EFB72094.1
gene_biotype: protein_coding
description:
  KEGG: bpm:BURPS1710b_A2293 2.7e-51 TetR-family regulatory protein K00356; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_06850
symbol: EFB72095.1
gene_biotype: protein_coding
description:
  Glutathione S-transferase, N-terminal domain protein; KEGG: psp:PSPPH_1249 9.1e-67 glutathione S-transferase K00799; Belongs to the GST superfamily.


ensembl_gene_id: PROVRUST_06858
symbol: EFB72103.1
gene_biotype: protein_coding
description:
  DNA-binding helix-turn-helix protein; KEGG: pac:PPA1226 0.0018 UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790.


ensembl_gene_id: PROVRUST_06864
symbol: EFB72109.1
gene_biotype: protein_coding
description:
  Integrase core domain protein; KEGG: cal:orf19.6807 0.0034 hypothetical protein similar to reverse transcripases K00986.


ensembl_gene_id: PROVRUST_06882
symbol: FrmA_2
gene_biotype: protein_coding
description:
  KEGG: eci:UTI89_C0376 4.4e-193 adhC; alcohol dehydrogenase class III; formaldehyde dehydrogenase, glutathione-dependent K00001:K00121; Psort location: Cytoplasmic, score: 9.97; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.


ensembl_gene_id: PROVRUST_06889
symbol: EFB72134.1
gene_biotype: protein_coding
description:
  LysR substrate binding domain protein; KEGG: shn:Shewana3_3435 1.4e-24 transcriptional regulator, LysR family K06022; Psort location: Cytoplasmic, score: 9.26; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: PROVRUST_06896
symbol: EFB72141.1
gene_biotype: protein_coding
description:
  DNA-binding helix-turn-helix protein; KEGG: pac:PPA1226 0.00026 UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790.


ensembl_gene_id: PROVRUST_06902
symbol: IaaA
gene_biotype: protein_coding
description:
  Asparaginase; KEGG: nmu:Nmul_A2166 1.8e-100 peptidase T2, asparaginase 2 K01424; Psort location: Periplasmic, score: 9.44.


ensembl_gene_id: PROVRUST_06905
symbol: HxuC_3
gene_biotype: protein_coding
description:
  TonB-dependent heme/hemoglobin receptor family protein; KEGG: shn:Shewana3_3063 0.0076 phosphatidylglycerophosphatase K01094; Psort location: OuterMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_06908
symbol: YfhA
gene_biotype: protein_coding
description:
  Iron chelate uptake ABC transporter, FeCT family, permease protein; KEGG: cjk:jk1986 0.0013 mnhB; NADH:ubiquinone oxidoreductase subunit 5 (chain L)/multisubunit Na+/H+ antiporter MnhA subunit K05565; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: PROVRUST_06909
symbol: hmuV
gene_biotype: protein_coding
description:
  Hemin import ATP-binding protein HmuV; Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system.


ensembl_gene_id: PROVRUST_06911
symbol: YcaD_2
gene_biotype: protein_coding
description:
  Transporter, major facilitator family protein; KEGG: neu:NE2389 0.0080 dsbD; thioredoxin:cytochrome c biogenesis protein transmembrane region K04084; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_06913
symbol: prpB
gene_biotype: protein_coding
description:
  Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.


ensembl_gene_id: PROVRUST_06914
symbol: PrpC
gene_biotype: protein_coding
description:
  KEGG: plu:plu3541 4.2e-156 prpC; 2-methylcitrate synthase (methylcitrate synthase) (citrate synthase 2) K01659; Psort location: Cytoplasmic, score: 9.26.


ensembl_gene_id: PROVRUST_06918
symbol: dbpA
gene_biotype: protein_coding
description:
  DEAD/DEAH box helicase; DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes.


ensembl_gene_id: PROVRUST_06920
symbol: FieF
gene_biotype: protein_coding
description:
  Cation diffusion facilitator family transporter; KEGG: mja:MJ0449 1.6e-39 cation efflux system protein K01529; Psort location: CytoplasmicMembrane, score: 9.46; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.


ensembl_gene_id: PROVRUST_06925
symbol: RhaS
gene_biotype: protein_coding
description:
  Transcriptional regulator, AraC family; KEGG: vvu:VV2_1208 1.5e-07 3-methyladenine DNA glycosylase K00567; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_06928
symbol: EFB71907.1
gene_biotype: protein_coding
description:
  M protein repeat protein; KEGG: yps:YPTB0915 5.5e-26 sbcC; putative ATP-dependent dsDNA exonuclease K03546.


ensembl_gene_id: PROVRUST_06929
symbol: EFB71605.1
gene_biotype: protein_coding
description:
  Hypothetical protein; KEGG: cal:orf19.6148 7.1e-16 USO2; intracellular protein transport K01553; Psort location: OuterMembrane, score: 9.83.


ensembl_gene_id: PROVRUST_06931
symbol: lysS
gene_biotype: protein_coding
description:
  lysine--tRNA ligase; KEGG: plu:plu3548 7.5e-246 lysS; lysyl-tRNA synthetase (lysine--tRNA ligase) K04567; Psort location: Cytoplasmic, score: 9.97; Belongs to the class-II aminoacyl-tRNA synthetase family.


ensembl_gene_id: PROVRUST_06932
symbol: prfB
gene_biotype: protein_coding
description:
  Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.


ensembl_gene_id: PROVRUST_06933
symbol: recJ
gene_biotype: protein_coding
description:
  KEGG: plu:plu3550 9.1e-225 recJ; single-stranded-DNA-specific exonuclease RecJ K07462; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_06934
symbol: DsbC
gene_biotype: protein_coding
description:
  Putative Thiol:disulfide interchange protein DsbC; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily.


ensembl_gene_id: PROVRUST_06935
symbol: xerD
gene_biotype: protein_coding
description:
  Tyrosine recombinase XerD; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerC binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerD specifically exchanges t [...]


ensembl_gene_id: PROVRUST_06939
symbol: YgfZ_2
gene_biotype: protein_coding
description:
  Glycine cleavage T-protein; Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication; Belongs to the tRNA-modifying YgfZ family.


ensembl_gene_id: PROVRUST_06940
symbol: EFB71616.1
gene_biotype: protein_coding
description:
  HD domain protein; KEGG: ypn:YPN_2153 2.9e-07 hypothetical protein K08722; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_06941
symbol: gcvP
gene_biotype: protein_coding
description:
  Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.


ensembl_gene_id: PROVRUST_06942
symbol: gcvH
gene_biotype: protein_coding
description:
  Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.


ensembl_gene_id: PROVRUST_06944
symbol: UbiF_2
gene_biotype: protein_coding
description:
  Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; KEGG: ecp:ECP_2899 1.3e-152 protein VisC.


ensembl_gene_id: PROVRUST_06945
symbol: ubiH
gene_biotype: protein_coding
description:
  2-polyprenyl-6-methoxyphenol 4-hydroxylase; KEGG: plu:plu3600 1.8e-139 ubiH; 2-octaprenyl-6-methoxyphenol hydroxylase K03185; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_06946
symbol: PepP
gene_biotype: protein_coding
description:
  Aminopeptidase P domain protein; KEGG: yps:YPTB3185 2.2e-182 pepP; proline-specific aminopeptidase K01262; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_06948
symbol: ZapA
gene_biotype: protein_coding
description:
  Cell division protein ZapA; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.


ensembl_gene_id: PROVRUST_06950
symbol: EFB71625.1
gene_biotype: protein_coding
description:
  KEGG: ype:YPO0913 1.0e-65 putative 5-formyltetrahydrofolate cyclo-ligase-family protein K01934; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_06951
symbol: SerA
gene_biotype: protein_coding
description:
  KEGG: plu:plu3605 2.3e-173 serA; D-3-phosphoglycerate dehydrogenase (PGDH) K00058; Psort location: Cytoplasmic, score: 9.97; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: PROVRUST_06953
symbol: rpiA
gene_biotype: protein_coding
description:
  Ribose 5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.


ensembl_gene_id: PROVRUST_06954
symbol: argP
gene_biotype: protein_coding
description:
  Transcriptional regulator, ArgP family; Controls the transcription of genes involved in arginine and lysine metabolism; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: PROVRUST_06956
symbol: argO
gene_biotype: protein_coding
description:
  Arginine exporter protein ArgO; Involved in the export of arginine. Important to control the intracellular level of arginine and the correct balance between arginine and lysine; Belongs to the LysE/ArgO transporter (TC 2.A.75) family.


ensembl_gene_id: PROVRUST_06957
symbol: MscS
gene_biotype: protein_coding
description:
  Transporter, small conductance mechanosensitive ion channel MscS family protein; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_06959
symbol: acnB
gene_biotype: protein_coding
description:
  Aconitate hydratase 2; KEGG: plu:plu3619 0. acnB; aconitate hydratase 2 (citrate hydro-lyase 2) (aconitase 2) K01682; Belongs to the aconitase/IPM isomerase family.


ensembl_gene_id: PROVRUST_06963
symbol: lpdA
gene_biotype: protein_coding
description:
  Dihydrolipoyl dehydrogenase; KEGG: eca:ECA3787 5.8e-239 lpdA, lpd; dihydrolipoamide dehydrogenase K00382; Psort location: Cytoplasmic, score: 9.97.


ensembl_gene_id: PROVRUST_06964
symbol: aceF
gene_biotype: protein_coding
description:
  Dihydrolipoyllysine-residue acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


ensembl_gene_id: PROVRUST_06965
symbol: aceE
gene_biotype: protein_coding
description:
  Pyruvate dehydrogenase (acetyl-transferring), homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


ensembl_gene_id: PROVRUST_06966
symbol: pdhR
gene_biotype: protein_coding
description:
  KEGG: bcz:BCZK3833 1.3e-06 transcriptional regulator, GntR family; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_06968
symbol: nadC
gene_biotype: protein_coding
description:
  Nicotinate-nucleotide diphosphorylase (carboxylating); KEGG: plu:plu3637 2.0e-101 nadC; nicotinate-nucleotide pyrophosphorylase [carboxylating] (quinolinate phosphoribosyltransferase [decarboxylating]) (QAPRTase) K00767; Psort location: Cytoplasmic, score: 9.97; Belongs to the NadC/ModD family.


ensembl_gene_id: PROVRUST_06969
symbol: ampD
gene_biotype: protein_coding
description:
  Protein AmpD; KEGG: eci:UTI89_C0118 8.2e-66 ampD; AmpD protein K03806; Psort location: Cytoplasmic, score: 9.97.


ensembl_gene_id: PROVRUST_06971
symbol: GspE
gene_biotype: protein_coding
description:
  KEGG: pen:PSEEN2333 2.6e-76 xcpR-2; type II secretion pathway protein E K01509; Psort location: Cytoplasmic, score: 9.97.


ensembl_gene_id: PROVRUST_06972
symbol: EFB71647.1
gene_biotype: protein_coding
description:
  Bacterial type II secretion system domain protein F; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_06973
symbol: coaE
gene_biotype: protein_coding
description:
  dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.


ensembl_gene_id: PROVRUST_06974
symbol: zapD
gene_biotype: protein_coding
description:
  Hypothetical protein; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.


ensembl_gene_id: PROVRUST_06975
symbol: yacG
gene_biotype: protein_coding
description:
  Hypothetical protein; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C- terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.


ensembl_gene_id: PROVRUST_06976
symbol: MutT
gene_biotype: protein_coding
description:
  KEGG: plu:plu3644 3.4e-44 mutT; mutator mutT protein (7,8-dihydro-8-oxoguanine-triphosphatase) (8-oxo-dGTPase) (dGTP pyrophosphohydrolase) K03574; Psort location: Cytoplasmic, score: 8.96; Belongs to the Nudix hydrolase family.


ensembl_gene_id: PROVRUST_06977
symbol: secA
gene_biotype: protein_coding
description:
  Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.


ensembl_gene_id: PROVRUST_06978
symbol: secM
gene_biotype: protein_coding
description:
  Secretion monitor precursor protein; Regulates secA expression by translational coupling of the secM secA operon. Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation initiation. Belongs to the SecM family.


ensembl_gene_id: PROVRUST_06980
symbol: lpxC
gene_biotype: protein_coding
description:
  UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family.


ensembl_gene_id: PROVRUST_06981
symbol: ftsZ
gene_biotype: protein_coding
description:
  Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.


ensembl_gene_id: PROVRUST_06982
symbol: ftsA
gene_biotype: protein_coding
description:
  Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.


ensembl_gene_id: PROVRUST_06983
symbol: ftsQ
gene_biotype: protein_coding
description:
  Cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.


ensembl_gene_id: PROVRUST_06986
symbol: murG
gene_biotype: protein_coding
description:
  Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.


ensembl_gene_id: PROVRUST_06987
symbol: ftsW
gene_biotype: protein_coding
description:
  Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily.


ensembl_gene_id: PROVRUST_06988
symbol: murD
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.


ensembl_gene_id: PROVRUST_06989
symbol: mraY
gene_biotype: protein_coding
description:
  phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.


ensembl_gene_id: PROVRUST_06990
symbol: murF
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.


ensembl_gene_id: PROVRUST_06991
symbol: murE
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.


ensembl_gene_id: PROVRUST_06992
symbol: ftsI
gene_biotype: protein_coding
description:
  Penicillin-binding protein, transpeptidase domain protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily.


ensembl_gene_id: PROVRUST_06993
symbol: ftsL
gene_biotype: protein_coding
description:
  Cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.


ensembl_gene_id: PROVRUST_06994
symbol: mraW
gene_biotype: protein_coding
description:
  S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.


ensembl_gene_id: PROVRUST_06995
symbol: mraZ
gene_biotype: protein_coding
description:
  Protein MraZ; Negatively regulates its own expression and that of the subsequent genes in the proximal part of the division and cell wall (dcw) gene cluster. Acts by binding directly to DNA. May also regulate the expression of genes outside the dcw cluster.


ensembl_gene_id: PROVRUST_06997
symbol: FruR
gene_biotype: protein_coding
description:
  D-fructose-responsive transcription factor; KEGG: efa:EF1922 2.6e-07 transcriptional regulator, LacI family/carbohydrate kinase, PfkB family protein K00852; Psort location: Cytoplasmic, score: 9.26.


ensembl_gene_id: PROVRUST_06998
symbol: ilvN
gene_biotype: protein_coding
description:
  KEGG: ypk:y3639 1.3e-74 ilvH; acetolactate synthase small subunit K01653; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_06999
symbol: ilvB-2
gene_biotype: protein_coding
description:
  Acetolactate synthase, large subunit, biosynthetic type; KEGG: plu:plu3666 2.6e-259 ilvI; acetolactate synthase isozyme III large subunit (AHAS-III) (acetohydroxy-acid synthase III large subunit) (ALS-III) K01652.


ensembl_gene_id: PROVRUST_07000
symbol: EFB71675.1
gene_biotype: protein_coding
description:
  AMP-binding enzyme; KEGG: plu:plu3671 5.1e-208 fadD; long-chain-fatty-acid--CoA ligase (long-chain acyl-CoA synthetase) (LACS) K01897; Psort location: Cytoplasmic, score: 9.26.


ensembl_gene_id: PROVRUST_07001
symbol: leuO
gene_biotype: protein_coding
description:
  Leucine transcriptional activator; KEGG: shn:Shewana3_3435 0.0082 transcriptional regulator, LysR family K06022; Psort location: Cytoplasmic, score: 9.26; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: PROVRUST_07002
symbol: leuA
gene_biotype: protein_coding
description:
  2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.


ensembl_gene_id: PROVRUST_07003
symbol: leuB
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.


ensembl_gene_id: PROVRUST_07004
symbol: leuC
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.


ensembl_gene_id: PROVRUST_07005
symbol: leuD
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.


ensembl_gene_id: PROVRUST_07008
symbol: mutH
gene_biotype: protein_coding
description:
  DNA mismatch repair endonuclease MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair. Belongs to the MutH family.


ensembl_gene_id: PROVRUST_07012
symbol: speB
gene_biotype: protein_coding
description:
  Agmatinase; Catalyzes the formation of putrescine from agmatine. Belongs to the arginase family. Agmatinase subfamily.


ensembl_gene_id: PROVRUST_07015
symbol: metK
gene_biotype: protein_coding
description:
  Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.


ensembl_gene_id: PROVRUST_07017
symbol: EFB71692.1
gene_biotype: protein_coding
description:
  YeeE/YedE family protein; KEGG: sgl:SG0807 0.0062 apolipoprotein N-acyltransferase K03820; Psort location: CytoplasmicMembrane, score: 9.46.


ensembl_gene_id: PROVRUST_07021
symbol: EFB71696.1
gene_biotype: protein_coding
description:
  KEGG: pmt:PMT0126 8.0e-36 MgtE family, putative magnesium transport protein K06213; Psort location: CytoplasmicMembrane, score: 9.46.


ensembl_gene_id: PROVRUST_07022
symbol: Hcr
gene_biotype: protein_coding
description:
  2Fe-2S iron-sulfur cluster binding domain protein; KEGG: eca:ECA2663 4.8e-116 hcr; NADH oxidoreductase.


ensembl_gene_id: PROVRUST_07024
symbol: clcA
gene_biotype: protein_coding
description:
  H(+)/Cl(-) exchange transporter ClcA; KEGG: cpr:CPR_1400 4.2e-62 chloride channel protein K01529; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_07025
symbol: tehB
gene_biotype: protein_coding
description:
  KEGG: eci:UTI89_C1650 2.1e-44 tehB; tellurite resistance protein TehB; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_07029
symbol: YceJ
gene_biotype: protein_coding
description:
  Nickel-dependent hydrogenases B-type cytochrome subunit; KEGG: reh:H16_A3123 1.2e-23 cytochrome b561 K00156; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_07030
symbol: DcmA
gene_biotype: protein_coding
description:
  Glutathione S-transferase, N-terminal domain protein; KEGG: rru:Rru_A3193 4.2e-46 glutathione S-transferase-like K04097.


ensembl_gene_id: PROVRUST_07031
symbol: mdcG
gene_biotype: protein_coding
description:
  Malonate decarboxylase holo-[acyl-carrier-protein] synthase; KEGG: pfl:PFL_5815 1.8e-15 mdcG; phosphoribosyl-dephospho-CoA transferase.


ensembl_gene_id: PROVRUST_07036
symbol: EFB71711.1
gene_biotype: protein_coding
description:
  NAD dependent epimerase/dehydratase family protein; KEGG: reh:H16_A2352 2.2e-40 putative NADH-flavin reductase K05901.


ensembl_gene_id: PROVRUST_07038
symbol: Rob_2
gene_biotype: protein_coding
description:
  KEGG: bcz:BCZK3497 2.7e-12 adaA; transcriptional regulator, AraC family K00567; Psort location: Cytoplasmic, score: 9.26.


ensembl_gene_id: PROVRUST_07043
symbol: dsbE
gene_biotype: protein_coding
description:
  Thiol:disulfide interchange protein DsbE; KEGG: azo:azo3929 2.6e-30 ccmG; protein disulfide-isomerase K01829; Psort location: Periplasmic, score: 9.44.


ensembl_gene_id: PROVRUST_07044
symbol: ccmF
gene_biotype: protein_coding
description:
  Cytochrome c-type biogenesis protein CcmF; KEGG: vfi:VF1819 5.3e-213 heme chaperone--apocytochrome heme-lyase K02198; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_07045
symbol: ccmE
gene_biotype: protein_coding
description:
  Cytochrome C-type biogenesis protein CcmE; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family.


ensembl_gene_id: PROVRUST_07046
symbol: ccmD
gene_biotype: protein_coding
description:
  Heme exporter protein CcmD; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmD/CycX/HelD family.


ensembl_gene_id: PROVRUST_07047
symbol: ccmC
gene_biotype: protein_coding
description:
  Heme exporter protein C; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family.


ensembl_gene_id: PROVRUST_07048
symbol: napC
gene_biotype: protein_coding
description:
  KEGG: eci:UTI89_C2480 2.9e-102 napC; cytochrome c protein, subunit of nitrate reductase, periplasmic K02569; Psort location: CytoplasmicMembrane, score: 8.02.


ensembl_gene_id: PROVRUST_07049
symbol: napB
gene_biotype: protein_coding
description:
  Periplasmic nitrate reductase, diheme cytochrome c subunit; Electron transfer subunit of the periplasmic nitrate reductase complex NapAB; Belongs to the NapB family.


ensembl_gene_id: PROVRUST_07050
symbol: napH
gene_biotype: protein_coding
description:
  KEGG: eci:UTI89_C2482 5.1e-128 napH; ferredoxin-type protein K02574; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_07051
symbol: napG
gene_biotype: protein_coding
description:
  KEGG: eci:UTI89_C2483 4.4e-106 napG; ferredoxin-type protein, subunit of nitrate reductase, periplasmic K02573; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_07052
symbol: napA
gene_biotype: protein_coding
description:
  Periplasmic nitrate reductase, large subunit; Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.


ensembl_gene_id: PROVRUST_07053
symbol: napD
gene_biotype: protein_coding
description:
  NapD protein; Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin- arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.


ensembl_gene_id: PROVRUST_07054
symbol: napF
gene_biotype: protein_coding
description:
  Ferredoxin-type protein NapF; Could be involved in the maturation of NapA, the catalytic subunit of the periplasmic nitrate reductase, before its export into the periplasm; Belongs to the NapF family.


ensembl_gene_id: PROVRUST_07055
symbol: nrfA
gene_biotype: protein_coding
description:
  Formate-dependent cytochrome c nitrite reductase, c552 subunit; Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process; Belongs to the cytochrome c-552 family.


ensembl_gene_id: PROVRUST_07057
symbol: nrfC
gene_biotype: protein_coding
description:
  Cytochrome c nitrite reductase, Fe-S protein; KEGG: vfi:VF1552 1.2e-80 thiosulfate reductase electron transport subunit K04014; Psort location: Cytoplasmic, score: 9.97.


ensembl_gene_id: PROVRUST_07058
symbol: nrfD
gene_biotype: protein_coding
description:
  KEGG: afu:AF2386 2.3e-22 molybdopterin oxidoreductase, membrane subunit K00185; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_07059
symbol: ccmF-2
gene_biotype: protein_coding
description:
  Cytochrome c-type biogenesis protein CcmF; KEGG: stm:STM4281 1.5e-185 nrfE; putative methylase K04016; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_07063
symbol: DnaK_2
gene_biotype: protein_coding
description:
  Putative chaperone; KEGG: eci:UTI89_C2848 6.9e-06 hscA; chaperone protein HscA K04044; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_07064
symbol: FbpC2
gene_biotype: protein_coding
description:
  KEGG: eca:ECA1468 2.6e-92 ABC transporter, ATP-binding protein K02010; Psort location: Cytoplasmic, score: 9.12.


ensembl_gene_id: PROVRUST_07065
symbol: CysW_4
gene_biotype: protein_coding
description:
  ABC transporter, permease protein; KEGG: ana:alr2433 3.1e-10 putative molybdate transport system permease/ATP-binding protein K02018; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_07067
symbol: SacA
gene_biotype: protein_coding
description:
  Sucrose-6-phosphate hydrolase; Enables the bacterium to metabolize sucrose as a sole carbon source; Belongs to the glycosyl hydrolase 32 family.


ensembl_gene_id: PROVRUST_07068
symbol: LacY
gene_biotype: protein_coding
description:
  oligosaccharide:H+ symporter; KEGG: hhe:HH1168 0.00011 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase K01000; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_07069
symbol: scrK
gene_biotype: protein_coding
description:
  Fructokinase; KEGG: ecp:ECP_2750 1.1e-109 fructokinase K00847; Psort location: Cytoplasmic, score: 9.97.


ensembl_gene_id: PROVRUST_07073
symbol: folD
gene_biotype: protein_coding
description:
  Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.


ensembl_gene_id: PROVRUST_07077
symbol: cysS
gene_biotype: protein_coding
description:
  cysteine--tRNA ligase; KEGG: ypn:YPN_1017 2.1e-216 cysteinyl-tRNA synthetase K01883; Psort location: Cytoplasmic, score: 9.97; Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: PROVRUST_07079
symbol: lpxH
gene_biotype: protein_coding
description:
  UDP-2,3-diacylglucosamine hydrolase; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: PROVRUST_07080
symbol: purE
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).


ensembl_gene_id: PROVRUST_07081
symbol: purK
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).


ensembl_gene_id: PROVRUST_07082
symbol: EFB71756.1
gene_biotype: protein_coding
description:
  Transporter, major facilitator family protein; KEGG: saz:Sama_1053 0.0034 oxaloacetate decarboxylase K01570; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_07087
symbol: LolD_3
gene_biotype: protein_coding
description:
  KEGG: pen:PSEEN1885 8.4e-64 ABC transporter, ATP-binding protein; Psort location: CytoplasmicMembrane, score: 7.88.


ensembl_gene_id: PROVRUST_07088
symbol: TesA
gene_biotype: protein_coding
description:
  GDSL-like protein; KEGG: plu:plu3818 8.4e-64 tesA; acyl-CoA thioesterase I precursor (protease I) (lysophospholipase L1) (lecithinase B) K01076; Psort location: Periplasmic, score: 9.44.


ensembl_gene_id: PROVRUST_07089
symbol: FabG_3
gene_biotype: protein_coding
description:
  Oxidoreductase, short chain dehydrogenase/reductase family protein; KEGG: plu:plu3819 1.5e-89 unnamed protein product; highly similar to hypothetical oxidoreductase YbbO of Escherichia coli; Psort location: Cytoplasmic, score: 9.26; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: PROVRUST_07090
symbol: YbbN_1
gene_biotype: protein_coding
description:
  Thioredoxin; KEGG: eci:UTI89_C0527 1.9e-91 ybbN; putative thioredoxin-like protein K05838; Psort location: Cytoplasmic, score: 9.26.


ensembl_gene_id: PROVRUST_07091
symbol: QmcA
gene_biotype: protein_coding
description:
  SPFH/Band 7/PHB domain protein; KEGG: reh:H16_A2036 1.4e-56 membrane protease subunits, stomatin/prohibitin homologs K01423.


ensembl_gene_id: PROVRUST_07093
symbol: CopA_3
gene_biotype: protein_coding
description:
  Copper-exporting ATPase; KEGG: plu:plu3824 0. copA; copper-transporting P-type ATPase K01533; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_07094
symbol: HdeD
gene_biotype: protein_coding
description:
  Putative protein HdeD; KEGG: btk:BT9727_0610 0.0014 qoxD; quinol oxidase, subunit IV (cytochrome C oxidase, subunit IV) K02829; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_07097
symbol: UshA_1
gene_biotype: protein_coding
description:
  5'-nucleotidase, C-terminal domain protein; KEGG: plu:plu3828 1.4e-253 ushA; protein UshA precursor [includes: UDP-sugar hydrolase (UDP-sugar diphosphatase) (UDP-sugar pyrophosphatase); 5'-nucleotidase (5'-NT)] K01081:K08077; Psort location: Periplasmic, score: 10.00; Belongs to the 5'-nucleotidase family.


ensembl_gene_id: PROVRUST_07098
symbol: Fsr
gene_biotype: protein_coding
description:
  Transporter, major facilitator family protein; KEGG: bba:Bd3281 0.00011 putative polysaccharide deacetylase K01463; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_07100
symbol: YbaL
gene_biotype: protein_coding
description:
  Transporter, CPA2 family; KEGG: nmu:Nmul_A2683 0.0056 protein-disulfide reductase K04084; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.


ensembl_gene_id: PROVRUST_07103
symbol: EFB71777.1
gene_biotype: protein_coding
description:
  Pyridine nucleotide-disulfide oxidoreductase; KEGG: ctc:CTC02435 2.1e-37 sarcosine oxidase alpha subunit K00301.


ensembl_gene_id: PROVRUST_07104
symbol: LhgO_2
gene_biotype: protein_coding
description:
  FAD dependent oxidoreductase; KEGG: sco:SCO7005 2.2e-88 SC8F11.31; glycerol-3-phosphate dehydrogenase K00111.


ensembl_gene_id: PROVRUST_07105
symbol: GlpK_1
gene_biotype: protein_coding
description:
  Putative glycerol kinase; KEGG: pae:PA1487 5.4e-124 probable carbohydrate kinase K00864; Psort location: Cytoplasmic, score: 8.96; Belongs to the FGGY kinase family.


ensembl_gene_id: PROVRUST_07108
symbol: FepE
gene_biotype: protein_coding
description:
  Chain length determinant protein; KEGG: cps:CPS_0580 0.0020 tyrosine-protein kinase K00903; Psort location: CytoplasmicMembrane, score: 9.82.


ensembl_gene_id: PROVRUST_07109
symbol: hemH
gene_biotype: protein_coding
description:
  Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.


ensembl_gene_id: PROVRUST_07110
symbol: adk
gene_biotype: protein_coding
description:
  Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.


ensembl_gene_id: PROVRUST_07112
symbol: recR
gene_biotype: protein_coding
description:
  Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.


ensembl_gene_id: PROVRUST_07113
symbol: YbaB
gene_biotype: protein_coding
description:
  DNA-binding protein, YbaB/EbfC family; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.


ensembl_gene_id: PROVRUST_07114
symbol: dnaX
gene_biotype: protein_coding
description:
  DNA polymerase III, subunit gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.


ensembl_gene_id: PROVRUST_07115
symbol: apt
gene_biotype: protein_coding
description:
  Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.


ensembl_gene_id: PROVRUST_07116
symbol: PriC
gene_biotype: protein_coding
description:
  Primosomal replication protein priB and priC; KEGG: dme:Dmel_CG14217 0.0027 Tao-1 K04429; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_07118
symbol: KefA_1
gene_biotype: protein_coding
description:
  Transporter, small conductance mechanosensitive ion channel MscS family protein; KEGG: gga:374182 2.1e-08 ROCK2; Rho-associated, coiled-coil containing protein kinase 2 K04514; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_07120
symbol: AcrR
gene_biotype: protein_coding
description:
  Transcriptional regulator, TetR family; KEGG: bcl:ABC2937 0.0015 NADH dehydrogenase K03885; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_07121
symbol: acrA
gene_biotype: protein_coding
description:
  Acriflavine resistance protein A; Psort location: CytoplasmicMembrane, score: 8.02; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: PROVRUST_07122
symbol: AcrB
gene_biotype: protein_coding
description:
  RND transporter, HAE1 family; KEGG: eci:UTI89_C2351 8.9e-108 yegO; hypothetical protein YegO K07789; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_07124
symbol: SdcS_2
gene_biotype: protein_coding
description:
  Transporter, DASS family; KEGG: ecj:JW3469 8.5e-07 arsB; arsenite/antimonite transporter K03893; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_07126
symbol: eno
gene_biotype: protein_coding
description:
  Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.


ensembl_gene_id: PROVRUST_07127
symbol: pyrG
gene_biotype: protein_coding
description:
  CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.


ensembl_gene_id: PROVRUST_07128
symbol: mazG
gene_biotype: protein_coding
description:
  Protein MazG; KEGG: pha:PSHAa0740 1.4e-63 mazG; nucleoside triphosphate pyrophosphohydrolase, non-specific K02428; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_07131
symbol: rumA
gene_biotype: protein_coding
description:
  23S rRNA (uracil-5-)-methyltransferase RumA; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.


ensembl_gene_id: PROVRUST_07132
symbol: dgt
gene_biotype: protein_coding
description:
  Putative dGTPase; dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs; Belongs to the dGTPase family. Type 1 subfamily.


ensembl_gene_id: PROVRUST_07133
symbol: mtnN
gene_biotype: protein_coding
description:
  MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulation. Belongs to the PNP/UDP phosphorylas [...]


ensembl_gene_id: PROVRUST_07134
symbol: btuF
gene_biotype: protein_coding
description:
  Periplasmic binding protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC.


ensembl_gene_id: PROVRUST_07135
symbol: erpA
gene_biotype: protein_coding
description:
  Iron-sulfur cluster insertion protein ErpA; Required for insertion of 4Fe-4S clusters for at least IspG.


ensembl_gene_id: PROVRUST_07136
symbol: hemL
gene_biotype: protein_coding
description:
  Glutamate-1-semialdehyde-2,1-aminomutase; KEGG: plu:plu0902 1.5e-199 hemL; glutamate-1-semialdehyde 2,1-aminomutase K01845.


ensembl_gene_id: PROVRUST_07137
symbol: mrcB
gene_biotype: protein_coding
description:
  Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).


ensembl_gene_id: PROVRUST_07139
symbol: sfsA
gene_biotype: protein_coding
description:
  Sugar fermentation stimulation protein; Psort location: Cytoplasmic, score: 8.96; Belongs to the SfsA family.


ensembl_gene_id: PROVRUST_07140
symbol: dksA
gene_biotype: protein_coding
description:
  RNA polymerase-binding protein DksA; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.


ensembl_gene_id: PROVRUST_07141
symbol: pcnB
gene_biotype: protein_coding
description:
  poly(A) polymerase; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control. Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.


ensembl_gene_id: PROVRUST_07142
symbol: folK
gene_biotype: protein_coding
description:
  2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; KEGG: plu:plu0873 6.1e-61 folK; 7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase K00950.


ensembl_gene_id: PROVRUST_07143
symbol: panB
gene_biotype: protein_coding
description:
  3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.


ensembl_gene_id: PROVRUST_07144
symbol: panC
gene_biotype: protein_coding
description:
  Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.


ensembl_gene_id: PROVRUST_07145
symbol: panD
gene_biotype: protein_coding
description:
  Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.


ensembl_gene_id: PROVRUST_07153
symbol: DrrA
gene_biotype: protein_coding
description:
  KEGG: pen:PSEEN1596 8.2e-105 ABC transporter, ATP-binding protein; Psort location: CytoplasmicMembrane, score: 7.88.


ensembl_gene_id: PROVRUST_07155
symbol: hpt
gene_biotype: protein_coding
description:
  Hypoxanthine phosphoribosyltransferase; KEGG: plu:plu0864 4.4e-74 unnamed protein product; highly similar to hypoxanthine phosphoribosyltransferase of Escherichia coli K00760; Psort location: Cytoplasmic, score: 9.97; Belongs to the purine/pyrimidine phosphoribosyltransferase family.


ensembl_gene_id: PROVRUST_07156
symbol: CueO
gene_biotype: protein_coding
description:
  Tat pathway signal sequence domain protein; KEGG: eci:UTI89_C0136 2.9e-180 cueO; blue copper oxidase CueO precursor; Psort location: Periplasmic, score: 9.44.


ensembl_gene_id: PROVRUST_07166
symbol: Ddh
gene_biotype: protein_coding
description:
  Diaminopimelate dehydrogenase; Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate.


ensembl_gene_id: PROVRUST_07168
symbol: EFB71842.1
gene_biotype: protein_coding
description:
  Hypothetical protein; KEGG: lac:LBA1398 0.00029 sdhA; L-serine dehydratase, alpha subunit K01752; Psort location: Cytoplasmic, score: 9.26; Belongs to the UPF0597 family.


ensembl_gene_id: PROVRUST_07169
symbol: YjiA
gene_biotype: protein_coding
description:
  CobW/P47K family protein; KEGG: reh:H16_A0195 1.2e-55 putative GTPase (G3E family); Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_07173
symbol: purT
gene_biotype: protein_coding
description:
  Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family.


ensembl_gene_id: PROVRUST_07175
symbol: RbsR_2
gene_biotype: protein_coding
description:
  Sugar-binding domain protein; KEGG: efa:EF1922 5.2e-06 transcriptional regulator, LacI family/carbohydrate kinase, PfkB family protein K00852; Psort location: Cytoplasmic, score: 9.97.


ensembl_gene_id: PROVRUST_07176
symbol: FixJ_2
gene_biotype: protein_coding
description:
  Transcriptional regulator, LuxR family; KEGG: rru:Rru_A1500 6.1e-16 signal transduction histidine kinase (STHK) with CheB and CheR activity K03412:K00575; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_07178
symbol: rimO
gene_biotype: protein_coding
description:
  Ribosomal protein S12 methylthiotransferase RimO; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily.


ensembl_gene_id: PROVRUST_07185
symbol: EfeB
gene_biotype: protein_coding
description:
  Tat-translocated enzyme; Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the tetrapyrrol ring intact. Belongs to the DyP-type peroxidase family.


ensembl_gene_id: PROVRUST_07186
symbol: EFB71860.1
gene_biotype: protein_coding
description:
  Von Willebrand factor type A domain protein; KEGG: cef:CE1890 0.00017 putative protoporphyrin IX magnesium chelatase K03404.


ensembl_gene_id: PROVRUST_07188
symbol: OxyR_1
gene_biotype: protein_coding
description:
  LysR substrate binding domain protein; KEGG: shn:Shewana3_3435 1.8e-20 transcriptional regulator, LysR family K06022; Psort location: Cytoplasmic, score: 9.26; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: PROVRUST_07189
symbol: ade
gene_biotype: protein_coding
description:
  Putative adenine deaminase; KEGG: sme:SMb21278 8.2e-153 adeC2; probable adenine deaminase protein K01486; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_07190
symbol: YicO
gene_biotype: protein_coding
description:
  Putative permease; KEGG: bcz:BCZK0244 1.6e-67 guanine-hypoxanthine permease; xanthine/uracil permease family protein K06901; Psort location: CytoplasmicMembrane, score: 10.00.


ensembl_gene_id: PROVRUST_07193
symbol: mdlC
gene_biotype: protein_coding
description:
  KEGG: msm:MSMEG_1606 3.3e-149 benzoylformate decarboxylase K01576; Psort location: CytoplasmicMembrane, score: 9.82; Belongs to the TPP enzyme family.


ensembl_gene_id: PROVRUST_07195
symbol: CynR_2
gene_biotype: protein_coding
description:
  LysR substrate binding domain protein; KEGG: shn:Shewana3_3435 7.8e-13 transcriptional regulator, LysR family K06022; Psort location: Cytoplasmic, score: 9.26; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: PROVRUST_07198
symbol: IpdC_1
gene_biotype: protein_coding
description:
  Thiamine pyrophosphate enzyme, N-terminal TPP binding domain protein; KEGG: mac:MA0594 5.4e-140 ipdC; indolepyruvate decarboxylase K01568.


ensembl_gene_id: PROVRUST_07199
symbol: YohD
gene_biotype: protein_coding
description:
  SNARE-like domain protein; KEGG: sab:SAB2386 2.0e-07 probable alkaline phosphatase K01077; Psort location: CytoplasmicMembrane, score: 9.46.


ensembl_gene_id: PROVRUST_07201
symbol: IpdC_2
gene_biotype: protein_coding
description:
  Thiamine pyrophosphate enzyme, N-terminal TPP binding domain protein; KEGG: mac:MA0594 6.6e-151 ipdC; indolepyruvate decarboxylase K01568; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_07202
symbol: GltC_3
gene_biotype: protein_coding
description:
  LysR substrate binding domain protein; KEGG: shn:Shewana3_3435 2.4e-34 transcriptional regulator, LysR family K06022; Psort location: Cytoplasmic, score: 9.26; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: PROVRUST_07204
symbol: mutS
gene_biotype: protein_coding
description:
  DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.


ensembl_gene_id: PROVRUST_07205
symbol: miaE
gene_biotype: protein_coding
description:
  KEGG: vpa:VP1099 1.1e-95 tRNA-(MS[2]IO[6]A)-hydroxylase K06169; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_07206
symbol: rpoS
gene_biotype: protein_coding
description:
  RNA polymerase sigma factor RpoS; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.


ensembl_gene_id: PROVRUST_07209
symbol: pcm
gene_biotype: protein_coding
description:
  protein-L-isoaspartate O-methyltransferase; Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.


ensembl_gene_id: PROVRUST_07210
symbol: surE
gene_biotype: protein_coding
description:
  5'/3'-nucleotidase SurE; Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP. Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20-25). Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs.


ensembl_gene_id: PROVRUST_07211
symbol: truD
gene_biotype: protein_coding
description:
  tRNA pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family.


ensembl_gene_id: PROVRUST_07212
symbol: ispF
gene_biotype: protein_coding
description:
  2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).


ensembl_gene_id: PROVRUST_07213
symbol: ispD
gene_biotype: protein_coding
description:
  2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.


ensembl_gene_id: PROVRUST_07214
symbol: ftsB
gene_biotype: protein_coding
description:
  Cell division protein FtsB; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.


ensembl_gene_id: PROVRUST_07216
symbol: cysN
gene_biotype: protein_coding
description:
  Sulfate adenylyltransferase, large subunit; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.


ensembl_gene_id: PROVRUST_07217
symbol: cysD
gene_biotype: protein_coding
description:
  KEGG: plu:plu0709 1.4e-148 cysD; sulfate adenylyltransferase subunit 2 (sulfate adenylate transferase) (SAT) (ATP-sulfurylase small subunit) K00957; Psort location: Cytoplasmic, score: 8.96.


ensembl_gene_id: PROVRUST_07218
symbol: cobA
gene_biotype: protein_coding
description:
  uroporphyrinogen-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family.  In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.


ensembl_gene_id: PROVRUST_07220
symbol: cysH
gene_biotype: protein_coding
description:
  Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.


