# geneInfo

ensembl_gene_id: HMPREF0494_0009
symbol: EEW54806.1
gene_biotype: protein_coding
description:
  CobQ/CobB/MinD/ParA nucleotide binding domain protein; COG: COG1192; Pfam: PF01656; InterPro: IPR002586.


ensembl_gene_id: HMPREF0494_0032
symbol: pncB
gene_biotype: protein_coding
description:
  Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.


ensembl_gene_id: HMPREF0494_0040
symbol: accA
gene_biotype: protein_coding
description:
  Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit; COG: COG0825; Pfam: PF03255; InterPro: IPR001095; overlaps another CDS with the same product name.


ensembl_gene_id: HMPREF0494_0041
symbol: accD
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.


ensembl_gene_id: HMPREF0494_0042
symbol: accC2
gene_biotype: protein_coding
description:
  Putative acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.


ensembl_gene_id: HMPREF0494_0043
symbol: fabZ
gene_biotype: protein_coding
description:
  Putative beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.


ensembl_gene_id: HMPREF0494_0044
symbol: accB
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.


ensembl_gene_id: HMPREF0494_0045
symbol: fabF
gene_biotype: protein_coding
description:
  Beta-ketoacyl-acyl-carrier-protein synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.


ensembl_gene_id: HMPREF0494_0046
symbol: fabG4
gene_biotype: protein_coding
description:
  Oxidoreductase, short chain dehydrogenase/reductase family protein; COG: COG1028; Pfam: PF00106; InterPro: IPR016040.


ensembl_gene_id: HMPREF0494_0048
symbol: acpP
gene_biotype: protein_coding
description:
  Putative acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.


ensembl_gene_id: HMPREF0494_0049
symbol: fabHA
gene_biotype: protein_coding
description:
  Beta-ketoacyl-acyl-carrier-protein synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.


ensembl_gene_id: HMPREF0494_0051
symbol: fabZ-2
gene_biotype: protein_coding
description:
  Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.


ensembl_gene_id: HMPREF0494_0059
symbol: thiM2
gene_biotype: protein_coding
description:
  Putative hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family.


ensembl_gene_id: HMPREF0494_0061
symbol: thiE
gene_biotype: protein_coding
description:
  Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.


ensembl_gene_id: HMPREF0494_0068
symbol: ykgC
gene_biotype: protein_coding
description:
  Pyridine nucleotide-disulfide oxidoreductase; COG: COG1249; Pfam: PF07992,PF00070,PF02852; InterPro: IPR013027.


ensembl_gene_id: HMPREF0494_0070
symbol: qor2
gene_biotype: protein_coding
description:
  Zinc-binding alcohol dehydrogenase family protein; COG: COG0604; Pfam: PF08240,PF00107; InterPro: IPR014182; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.


ensembl_gene_id: HMPREF0494_0079
symbol: birA2
gene_biotype: protein_coding
description:
  biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.


ensembl_gene_id: HMPREF0494_0091
symbol: yfiG3
gene_biotype: protein_coding
description:
  MFS transporter, SP family; COG: COG0477; Pfam: PF00083; InterPro: IPR005828; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.


ensembl_gene_id: HMPREF0494_0102
symbol: mntH2
gene_biotype: protein_coding
description:
  Metal ion transporter, metal ion (Mn2+/Fe2+) transporter (Nramp) family; COG: COG1914; Pfam: PF01566; InterPro: IPR001046.


ensembl_gene_id: HMPREF0494_0103
symbol: hemH
gene_biotype: protein_coding
description:
  Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.


ensembl_gene_id: HMPREF0494_0116
symbol: metN3
gene_biotype: protein_coding
description:
  ABC transporter, ATP-binding protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.


ensembl_gene_id: HMPREF0494_0117
symbol: metQ2
gene_biotype: protein_coding
description:
  NLPA lipoprotein; COG: COG1464; Pfam: PF03180; InterPro: IPR004872; Belongs to the nlpA lipoprotein family.


ensembl_gene_id: HMPREF0494_0121
symbol: EEW54645.1
gene_biotype: protein_coding
description:
  Putative chlorophyll synthesis pathway protein BchC; COG: COG1063; Pfam: PF08240,PF00107; InterPro: IPR002085.


ensembl_gene_id: HMPREF0494_0123
symbol: hicD5
gene_biotype: protein_coding
description:
  L-2-hydroxyisocaproate dehydrogenase; COG: COG0039; Pfam: PF00056,PF02866; InterPro: IPR001236; Belongs to the LDH/MDH superfamily.


ensembl_gene_id: HMPREF0494_0129
symbol: nagB
gene_biotype: protein_coding
description:
  Glucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.


ensembl_gene_id: HMPREF0494_0131
symbol: nanE
gene_biotype: protein_coding
description:
  Putative N-acetylmannosamine-6-phosphate epimerase; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P).


ensembl_gene_id: HMPREF0494_0134
symbol: nanA
gene_biotype: protein_coding
description:
  Putative N-acetylneuraminate lyase; COG: COG0329; Pfam: PF00701; InterPro: IPR002220; Belongs to the DapA family.


ensembl_gene_id: HMPREF0494_0140
symbol: nth
gene_biotype: protein_coding
description:
  Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.


ensembl_gene_id: HMPREF0494_0147
symbol: apbA
gene_biotype: protein_coding
description:
  2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.


ensembl_gene_id: HMPREF0494_0149
symbol: napA
gene_biotype: protein_coding
description:
  Transporter, CPA2 family; COG: COG0475; Pfam: PF00999; InterPro: IPR006153; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.


ensembl_gene_id: HMPREF0494_0151
symbol: ndk
gene_biotype: protein_coding
description:
  Nucleoside diphosphate kinase; COG: COG0105; Pfam: PF00334; InterPro: IPR001564; Belongs to the NDK family.


ensembl_gene_id: HMPREF0494_0172
symbol: EEW54696.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG: COG3681; Pfam: PF06354; InterPro: IPR010469; Belongs to the UPF0597 family.


ensembl_gene_id: HMPREF0494_0173
symbol: EEW54697.1
gene_biotype: protein_coding
description:
  Transporter, dicarboxylate/amino acid:cation Na+/H+ symporter family protein; COG: COG1823; Pfam: PF00375; InterPro: IPR001991; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: HMPREF0494_0178
symbol: trpS
gene_biotype: protein_coding
description:
  tryptophan--tRNA ligase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: HMPREF0494_0180
symbol: mvaA
gene_biotype: protein_coding
description:
  hydroxymethylglutaryl-CoA reductase, degradative; COG: COG1257; InterPro: IPR004553; Belongs to the HMG-CoA reductase family.


ensembl_gene_id: HMPREF0494_0185
symbol: feoB
gene_biotype: protein_coding
description:
  Ferrous iron transport protein B; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.


ensembl_gene_id: HMPREF0494_0189
symbol: sufS
gene_biotype: protein_coding
description:
  Cysteine desulfurase, SufS subfamily; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.


ensembl_gene_id: HMPREF0494_0196
symbol: metG
gene_biotype: protein_coding
description:
  methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.


ensembl_gene_id: HMPREF0494_0198
symbol: rnmV
gene_biotype: protein_coding
description:
  Ribonuclease M5; Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.


ensembl_gene_id: HMPREF0494_0199
symbol: ksgA
gene_biotype: protein_coding
description:
  Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.


ensembl_gene_id: HMPREF0494_0201
symbol: ispE
gene_biotype: protein_coding
description:
  4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.


ensembl_gene_id: HMPREF0494_0208
symbol: glmU
gene_biotype: protein_coding
description:
  UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.


ensembl_gene_id: HMPREF0494_0209
symbol: prs
gene_biotype: protein_coding
description:
  Ribose-phosphate diphosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.


ensembl_gene_id: HMPREF0494_0211
symbol: bsh
gene_biotype: protein_coding
description:
  Linear amide C-N hydrolase, choloylglycine hydrolase family protein; COG: COG3049; Pfam: PF02275; InterPro: IPR003199.


ensembl_gene_id: HMPREF0494_0217
symbol: rpoE
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase, delta subunit; Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; Belongs to the RpoE family.


ensembl_gene_id: HMPREF0494_0218
symbol: pyrG
gene_biotype: protein_coding
description:
  CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.


ensembl_gene_id: HMPREF0494_0219
symbol: murA
gene_biotype: protein_coding
description:
  UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.


ensembl_gene_id: HMPREF0494_0223
symbol: EEW54599.1
gene_biotype: protein_coding
description:
  Low molecular weight phosphotyrosine protein phosphatase; COG: COG0394; Pfam: PF01451; InterPro: IPR000106; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.


ensembl_gene_id: HMPREF0494_0225
symbol: htpX
gene_biotype: protein_coding
description:
  Peptidase, M48 family; COG: COG0501; Pfam: PF01435; InterPro: IPR001915; Belongs to the peptidase M48B family.


ensembl_gene_id: HMPREF0494_0228
symbol: pepI
gene_biotype: protein_coding
description:
  Prolyl aminopeptidase; Releases the N-terminal proline from various substrates. Belongs to the peptidase S33 family.


ensembl_gene_id: HMPREF0494_0229
symbol: prdA
gene_biotype: protein_coding
description:
  Glycine/sarcosine/betaine reductase component B subunit alpha and beta; Pfam: PF09338; InterPro: IPR015417.


ensembl_gene_id: HMPREF0494_0235
symbol: EEW54611.1
gene_biotype: protein_coding
description:
  Proline racemase; COG: COG3938; Pfam: PF05544; InterPro: IPR008794; Belongs to the proline racemase family.


ensembl_gene_id: HMPREF0494_0240
symbol: selB
gene_biotype: protein_coding
description:
  Selenocysteine-specific translation elongation factor; COG: COG3276; Pfam: PF00009,PF03144,PF09107; InterPro: IPR004535.


ensembl_gene_id: HMPREF0494_0242
symbol: selA
gene_biotype: protein_coding
description:
  L-seryl-tRNA(Sec) selenium transferase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.


ensembl_gene_id: HMPREF0494_0244
symbol: murF
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.


ensembl_gene_id: HMPREF0494_0245
symbol: rhe2
gene_biotype: protein_coding
description:
  DEAD/DEAH box helicase; DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA-dependent ATPase activity; Belongs to the DEAD box helicase family. CshA subfamily.


ensembl_gene_id: HMPREF0494_0247
symbol: dltC
gene_biotype: protein_coding
description:
  D-alanine--poly(phosphoribitol) ligase, subunit 2; Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC- carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.


ensembl_gene_id: HMPREF0494_0248
symbol: dtlB
gene_biotype: protein_coding
description:
  MBOAT family protein; Could be involved in the transport of activated D-alanine through the membrane.


ensembl_gene_id: HMPREF0494_0249
symbol: dltA
gene_biotype: protein_coding
description:
  D-alanine--poly(phosphoribitol) ligase, subunit 1; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to [...]


ensembl_gene_id: HMPREF0494_0250
symbol: alr
gene_biotype: protein_coding
description:
  Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.


ensembl_gene_id: HMPREF0494_0251
symbol: mazF
gene_biotype: protein_coding
description:
  Toxin-antitoxin system, toxin component, MazF family; Toxic component of a type II toxin-antitoxin (TA) system.


ensembl_gene_id: HMPREF0494_0253
symbol: pth
gene_biotype: protein_coding
description:
  aminoacyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.


ensembl_gene_id: HMPREF0494_0254
symbol: mfd
gene_biotype: protein_coding
description:
  Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.


ensembl_gene_id: HMPREF0494_0258
symbol: tilS
gene_biotype: protein_coding
description:
  tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.


ensembl_gene_id: HMPREF0494_0259
symbol: hpt
gene_biotype: protein_coding
description:
  Hypoxanthine phosphoribosyltransferase; COG: COG0634; Pfam: PF00156; InterPro: IPR005904; Belongs to the purine/pyrimidine phosphoribosyltransferase family.


ensembl_gene_id: HMPREF0494_0260
symbol: hflB
gene_biotype: protein_coding
description:
  ATP-dependent metallopeptidase HflB; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family.  In the central section; belongs to the AAA ATPase family.


ensembl_gene_id: HMPREF0494_0261
symbol: hslO
gene_biotype: protein_coding
description:
  Chaperonin HslO; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.


ensembl_gene_id: HMPREF0494_0262
symbol: dus
gene_biotype: protein_coding
description:
  TIM-barrel protein, nifR3 family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.


ensembl_gene_id: HMPREF0494_0263
symbol: lysS
gene_biotype: protein_coding
description:
  lysine--tRNA ligase; COG: COG1190; Pfam: PF01336,PF00152; InterPro: IPR002313; Belongs to the class-II aminoacyl-tRNA synthetase family.


ensembl_gene_id: HMPREF0494_0267
symbol: tyrS
gene_biotype: protein_coding
description:
  tyrosine--tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.


ensembl_gene_id: HMPREF0494_0270
symbol: gpm
gene_biotype: protein_coding
description:
  Phosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.


ensembl_gene_id: HMPREF0494_0271
symbol: EEW54529.1
gene_biotype: protein_coding
description:
  Gram-positive signal peptide protein, YSIRK family; Pfam: PF04650,PF08428,PF00746; InterPro: IPR012706.


ensembl_gene_id: HMPREF0494_0276
symbol: purD
gene_biotype: protein_coding
description:
  Phosphoribosylamine--glycine ligase; COG: COG0151; Pfam: PF02844,PF01071,PF02843; InterPro: IPR000115; Belongs to the GARS family.


ensembl_gene_id: HMPREF0494_0277
symbol: purH
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; COG: COG0138; Pfam: PF02142,PF01808; InterPro: IPR002695.


ensembl_gene_id: HMPREF0494_0278
symbol: purN
gene_biotype: protein_coding
description:
  Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.


ensembl_gene_id: HMPREF0494_0279
symbol: purM
gene_biotype: protein_coding
description:
  Phosphoribosylformylglycinamidine cyclo-ligase; COG: COG0150; Pfam: PF00586,PF02769; InterPro: IPR004733.


ensembl_gene_id: HMPREF0494_0280
symbol: purF
gene_biotype: protein_coding
description:
  Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.


ensembl_gene_id: HMPREF0494_0281
symbol: purL
gene_biotype: protein_coding
description:
  Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist  [...]


ensembl_gene_id: HMPREF0494_0282
symbol: purQ
gene_biotype: protein_coding
description:
  Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...]


ensembl_gene_id: HMPREF0494_0283
symbol: purS
gene_biotype: protein_coding
description:
  Phosphoribosylformylglycinamidine synthase, purS protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...]


ensembl_gene_id: HMPREF0494_0284
symbol: purC
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazolesuccinocarboxamide synthase; COG: COG0152; Pfam: PF01259; InterPro: IPR001636; Belongs to the SAICAR synthetase family.


ensembl_gene_id: HMPREF0494_0287
symbol: purB
gene_biotype: protein_coding
description:
  Adenylosuccinate lyase; COG: COG0015; Pfam: PF00206; InterPro: IPR004769; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.


ensembl_gene_id: HMPREF0494_0288
symbol: purK
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).


ensembl_gene_id: HMPREF0494_0289
symbol: purE
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).


ensembl_gene_id: HMPREF0494_0294
symbol: ilvB
gene_biotype: protein_coding
description:
  Acetolactate synthase, large subunit, biosynthetic type; COG: COG0028; Pfam: PF02776,PF00205,PF02775; InterPro: IPR012846.


ensembl_gene_id: HMPREF0494_0295
symbol: ilvC
gene_biotype: protein_coding
description:
  Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.


ensembl_gene_id: HMPREF0494_0298
symbol: fhs
gene_biotype: protein_coding
description:
  Formate--tetrahydrofolate ligase; COG: COG2759; Pfam: PF01268; InterPro: IPR000559; Belongs to the formate--tetrahydrofolate ligase family.


ensembl_gene_id: HMPREF0494_0302
symbol: budA
gene_biotype: protein_coding
description:
  Alpha-acetolactate decarboxylase; COG: COG3527; Pfam: PF03306; InterPro: IPR005128; Belongs to the alpha-acetolactate decarboxylase family.


ensembl_gene_id: HMPREF0494_0303
symbol: alsS
gene_biotype: protein_coding
description:
  Acetolactate synthase, catabolic; COG: COG0028; Pfam: PF02776,PF00205,PF02775; InterPro: IPR012782; Belongs to the TPP enzyme family.


ensembl_gene_id: HMPREF0494_0309
symbol: hicD
gene_biotype: protein_coding
description:
  Lactate/malate dehydrogenase, NAD binding domain protein; COG: COG0039; Pfam: PF00056,PF02866; InterPro: IPR001236; Belongs to the LDH/MDH superfamily.


ensembl_gene_id: HMPREF0494_0310
symbol: pyrE
gene_biotype: protein_coding
description:
  Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).


ensembl_gene_id: HMPREF0494_0311
symbol: pyrF
gene_biotype: protein_coding
description:
  Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.


ensembl_gene_id: HMPREF0494_0312
symbol: pyrDB
gene_biotype: protein_coding
description:
  Dihydroorotate dehydrogenase B, catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate.


ensembl_gene_id: HMPREF0494_0315
symbol: EEW54515.1
gene_biotype: protein_coding
description:
  ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; COG: COG0642; Pfam: PF00512,PF02518; InterPro: IPR003594.


ensembl_gene_id: HMPREF0494_0316
symbol: EEW54516.1
gene_biotype: protein_coding
description:
  Response regulator receiver domain protein; COG: COG0745; Pfam: PF00072,PF00486; InterPro: IPR001789.


ensembl_gene_id: HMPREF0494_0317
symbol: epsA
gene_biotype: protein_coding
description:
  Cell envelope-like function transcriptional attenuator common domain protein; COG: COG1316; Pfam: PF03816; InterPro: IPR004474.


ensembl_gene_id: HMPREF0494_0318
symbol: guaB
gene_biotype: protein_coding
description:
  Putative inosine-5'-monophosphate dehydrogenase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.


ensembl_gene_id: HMPREF0494_0321
symbol: pdp
gene_biotype: protein_coding
description:
  Pyrimidine-nucleoside phosphorylase; COG: COG0213; Pfam: PF02885,PF00591,PF07831; InterPro: IPR000053.


ensembl_gene_id: HMPREF0494_0322
symbol: deoB
gene_biotype: protein_coding
description:
  Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family.


ensembl_gene_id: HMPREF0494_0323
symbol: deoC
gene_biotype: protein_coding
description:
  Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.


ensembl_gene_id: HMPREF0494_0326
symbol: ychF
gene_biotype: protein_coding
description:
  GTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.


ensembl_gene_id: HMPREF0494_0331
symbol: gidB
gene_biotype: protein_coding
description:
  16S rRNA methyltransferase GidB; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.


ensembl_gene_id: HMPREF0494_0339
symbol: serS
gene_biotype: protein_coding
description:
  serine--tRNA ligase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).


ensembl_gene_id: HMPREF0494_0340
symbol: EEW54452.1
gene_biotype: protein_coding
description:
  Gram-positive signal peptide protein, YSIRK family; Pfam: PF04650,PF08428,PF06458,PF00746; InterPro: IPR012706.


ensembl_gene_id: HMPREF0494_0342
symbol: EEW54454.1
gene_biotype: protein_coding
description:
  ApbE family protein; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.


ensembl_gene_id: HMPREF0494_0345
symbol: rumA
gene_biotype: protein_coding
description:
  23S rRNA (uracil-5-)-methyltransferase RumA; COG: COG2265; Pfam: PF01938,PF05958; InterPro: IPR001566; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.


ensembl_gene_id: HMPREF0494_0347
symbol: pyrR2
gene_biotype: protein_coding
description:
  Phosphoribosyl transferase domain protein; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant; Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.


ensembl_gene_id: HMPREF0494_0350
symbol: purA
gene_biotype: protein_coding
description:
  Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.


ensembl_gene_id: HMPREF0494_0351
symbol: guaC
gene_biotype: protein_coding
description:
  GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides; Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.


ensembl_gene_id: HMPREF0494_0355
symbol: glpQ
gene_biotype: protein_coding
description:
  Glycerophosphodiester phosphodiesterase family protein; COG: COG0584; Pfam: PF03009; InterPro: IPR004129.


ensembl_gene_id: HMPREF0494_0358
symbol: akr5f4
gene_biotype: protein_coding
description:
  Oxidoreductase, aldo/keto reductase family protein; COG: COG0656; Pfam: PF00248; InterPro: IPR001395.


ensembl_gene_id: HMPREF0494_0361
symbol: map
gene_biotype: protein_coding
description:
  Glycosyl hydrolase family 65 central catalytic domain protein; COG: COG1554; Pfam: PF03636,PF03632,PF03633; InterPro: IPR005195.


ensembl_gene_id: HMPREF0494_0363
symbol: atoB
gene_biotype: protein_coding
description:
  acetyl-CoA C-acetyltransferase; COG: COG0183; Pfam: PF00108,PF02803; InterPro: IPR002155; Belongs to the thiolase-like superfamily. Thiolase family.


ensembl_gene_id: HMPREF0494_0373
symbol: cls
gene_biotype: protein_coding
description:
  Phospholipase D domain protein; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.


ensembl_gene_id: HMPREF0494_0375
symbol: ldhA
gene_biotype: protein_coding
description:
  D-lactate dehydrogenase; COG: COG1052; Pfam: PF00389,PF02826; InterPro: IPR006139; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: HMPREF0494_0376
symbol: clpL
gene_biotype: protein_coding
description:
  ATPase family associated with various cellular activities (AAA); COG: COG0542; Pfam: PF00004,PF07724; InterPro: IPR013093; Belongs to the ClpA/ClpB family.


ensembl_gene_id: HMPREF0494_0380
symbol: pdxB
gene_biotype: protein_coding
description:
  4-phosphoerythronate dehydrogenase; COG: COG1052; Pfam: PF00389,PF02826; InterPro: IPR006139; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: HMPREF0494_0384
symbol: EEW54396.1
gene_biotype: protein_coding
description:
  DNA (cytosine-5-)-methyltransferase; COG: COG0863; Pfam: PF01555; InterPro: IPR002941; Belongs to the N(4)/N(6)-methyltransferase family.


ensembl_gene_id: HMPREF0494_0390
symbol: rlmH
gene_biotype: protein_coding
description:
  rRNA large subunit m3Psi methyltransferase RlmH; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family.


ensembl_gene_id: HMPREF0494_0399
symbol: EEW54411.1
gene_biotype: protein_coding
description:
  Oxidoreductase, aldo/keto reductase family protein; COG: COG4989; Pfam: PF00248; InterPro: IPR001395.


ensembl_gene_id: HMPREF0494_0400
symbol: EEW54412.1
gene_biotype: protein_coding
description:
  Oxidoreductase, aldo/keto reductase family protein; COG: COG0667; Pfam: PF00248; InterPro: IPR001395.


ensembl_gene_id: HMPREF0494_0404
symbol: metN
gene_biotype: protein_coding
description:
  ABC transporter, ATP-binding protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.


ensembl_gene_id: HMPREF0494_0407
symbol: EEW54419.1
gene_biotype: protein_coding
description:
  Polyphosphate:nucleotide phosphotransferase, PPK2 family; COG: COG2326; Pfam: PF03976; InterPro: IPR005660.


ensembl_gene_id: HMPREF0494_0410
symbol: gabD
gene_biotype: protein_coding
description:
  Aldehyde dehydrogenase (NAD) family protein; COG: COG1012; Pfam: PF00171; InterPro: IPR015590; Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: HMPREF0494_0415
symbol: dnaB
gene_biotype: protein_coding
description:
  Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily.


ensembl_gene_id: HMPREF0494_0417
symbol: EEW54429.1
gene_biotype: protein_coding
description:
  DHHA1 domain protein; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family.


ensembl_gene_id: HMPREF0494_0418
symbol: rpsR
gene_biotype: protein_coding
description:
  Ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.


ensembl_gene_id: HMPREF0494_0419
symbol: ssb
gene_biotype: protein_coding
description:
  Single-strand binding family protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.


ensembl_gene_id: HMPREF0494_0421
symbol: gyrA
gene_biotype: protein_coding
description:
  DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.


ensembl_gene_id: HMPREF0494_0422
symbol: gyrB
gene_biotype: protein_coding
description:
  DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.


ensembl_gene_id: HMPREF0494_0423
symbol: recF
gene_biotype: protein_coding
description:
  DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family.


ensembl_gene_id: HMPREF0494_0425
symbol: dnaN
gene_biotype: protein_coding
description:
  DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]


ensembl_gene_id: HMPREF0494_0426
symbol: dnaA
gene_biotype: protein_coding
description:
  Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.


ensembl_gene_id: HMPREF0494_0427
symbol: rpmH
gene_biotype: protein_coding
description:
  Ribosomal protein L34; COG: COG0230; Pfam: PF00468; InterPro: IPR000271; Belongs to the bacterial ribosomal protein bL34 family.


ensembl_gene_id: HMPREF0494_0428
symbol: rnpA
gene_biotype: protein_coding
description:
  Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.


ensembl_gene_id: HMPREF0494_0429
symbol: spoIIIJ
gene_biotype: protein_coding
description:
  Membrane protein insertase, YidC/Oxa1 family; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins; Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily.


ensembl_gene_id: HMPREF0494_0430
symbol: gshA
gene_biotype: protein_coding
description:
  Glutamate-cysteine ligase; COG: COG2918; Pfam: PF04262; InterPro: IPR007370; Belongs to the glutamate--cysteine ligase type 1 family.


ensembl_gene_id: HMPREF0494_0433
symbol: trmE
gene_biotype: protein_coding
description:
  tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.


ensembl_gene_id: HMPREF0494_0434
symbol: gidA
gene_biotype: protein_coding
description:
  tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family.


ensembl_gene_id: HMPREF0494_0435
symbol: asnB
gene_biotype: protein_coding
description:
  Asparagine synthase (glutamine-hydrolyzing); COG: COG0367; Pfam: PF00310,PF00733; InterPro: IPR006426.


ensembl_gene_id: HMPREF0494_0436
symbol: murE
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.


ensembl_gene_id: HMPREF0494_0437
symbol: lepB
gene_biotype: protein_coding
description:
  Signal peptidase I; COG: COG0681; Pfam: PF00717; InterPro: IPR000223; Belongs to the peptidase S26 family.


ensembl_gene_id: HMPREF0494_0452
symbol: EEW54269.1
gene_biotype: protein_coding
description:
  Pyridine nucleotide-disulfide oxidoreductase; COG: COG0493; Pfam: PF07992,PF00070; InterPro: IPR013027.


ensembl_gene_id: HMPREF0494_0460
symbol: ribD
gene_biotype: protein_coding
description:
  Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.


ensembl_gene_id: HMPREF0494_0462
symbol: ribA
gene_biotype: protein_coding
description:
  GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the GTP cyclohydrolase II family.  In the N-terminal section; belongs to the DHBP synthase family.


ensembl_gene_id: HMPREF0494_0463
symbol: ribH
gene_biotype: protein_coding
description:
  6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.


ensembl_gene_id: HMPREF0494_0469
symbol: crcB
gene_biotype: protein_coding
description:
  Putative protein CrcB; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.


ensembl_gene_id: HMPREF0494_0471
symbol: EEW54288.1
gene_biotype: protein_coding
description:
  NAD dependent epimerase/dehydratase family protein; COG: COG0702; Pfam: PF01370; InterPro: IPR016040.


ensembl_gene_id: HMPREF0494_0474
symbol: EEW54291.1
gene_biotype: protein_coding
description:
  Transcriptional regulatory protein, C-terminal domain protein; COG: COG0745; Pfam: PF00486; InterPro: IPR011991.


ensembl_gene_id: HMPREF0494_0476
symbol: pstC
gene_biotype: protein_coding
description:
  Phosphate ABC transporter, permease protein PstC; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: HMPREF0494_0478
symbol: pstB
gene_biotype: protein_coding
description:
  Phosphate ABC transporter, ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.


ensembl_gene_id: HMPREF0494_0479
symbol: phoU
gene_biotype: protein_coding
description:
  Phosphate transport system regulatory protein PhoU; Plays a role in the regulation of phosphate uptake.


ensembl_gene_id: HMPREF0494_0480
symbol: pepC
gene_biotype: protein_coding
description:
  Peptidase C1-like family; COG: COG3579; Pfam: PF03051; InterPro: IPR004134; Belongs to the peptidase C1 family.


ensembl_gene_id: HMPREF0494_0481
symbol: EEW54298.1
gene_biotype: protein_coding
description:
  Alkylhydroperoxidase AhpD family core domain protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.


ensembl_gene_id: HMPREF0494_0488
symbol: asd
gene_biotype: protein_coding
description:
  Aspartate-semialdehyde dehydrogenase; COG: COG0136; Pfam: PF01118,PF02774; InterPro: IPR005676; Belongs to the aspartate-semialdehyde dehydrogenase family.


ensembl_gene_id: HMPREF0494_0494
symbol: ribB
gene_biotype: protein_coding
description:
  3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. Belongs to the DHBP synthase family.


ensembl_gene_id: HMPREF0494_0497
symbol: EEW54314.1
gene_biotype: protein_coding
description:
  Cytochrome b5-like Heme/Steroid binding domain protein; COG: COG4892; Pfam: PF00173; InterPro: IPR001199.


ensembl_gene_id: HMPREF0494_0498
symbol: npp
gene_biotype: protein_coding
description:
  Type I phosphodiesterase / nucleotide pyrophosphatase; COG: COG1524; Pfam: PF01663; InterPro: IPR002591.


ensembl_gene_id: HMPREF0494_0506
symbol: thrS
gene_biotype: protein_coding
description:
  threonine--tRNA ligase; COG: COG0441; Pfam: PF07973,PF00587,PF03129; InterPro: IPR002320; Belongs to the class-II aminoacyl-tRNA synthetase family.


ensembl_gene_id: HMPREF0494_0523
symbol: EEW54340.1
gene_biotype: protein_coding
description:
  Nitroreductase family protein; COG: COG0778; Pfam: PF00881; InterPro: IPR000415; Belongs to the flavin oxidoreductase frp family.


ensembl_gene_id: HMPREF0494_0524
symbol: nnrE
gene_biotype: protein_coding
description:
  YjeF-like protein; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX; Belongs to the NnrE/AIBP family.


ensembl_gene_id: HMPREF0494_0529
symbol: EEW54346.1
gene_biotype: protein_coding
description:
  DNA-3-methyladenine glycosylase; COG: COG2094; Pfam: PF02245; InterPro: IPR003180; Belongs to the DNA glycosylase MPG family.


ensembl_gene_id: HMPREF0494_0537
symbol: pgi
gene_biotype: protein_coding
description:
  Glucose-6-phosphate isomerase; COG: COG0166; Pfam: PF00342; InterPro: IPR001672; overlaps another CDS with the same product name.


ensembl_gene_id: HMPREF0494_0538
symbol: EEW54355.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG: COG0166; Pfam: PF00342; InterPro: IPR001672; overlaps another CDS with the same product name; 5.3.1.9.


ensembl_gene_id: HMPREF0494_0544
symbol: EEW54361.1
gene_biotype: protein_coding
description:
  ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; COG: COG0642; Pfam: PF02518; InterPro: IPR003594.


ensembl_gene_id: HMPREF0494_0550
symbol: greA
gene_biotype: protein_coding
description:
  Transcription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.


ensembl_gene_id: HMPREF0494_0553
symbol: ald
gene_biotype: protein_coding
description:
  Alanine dehydrogenase; COG: COG0686; Pfam: PF05222,PF01262; InterPro: IPR008141; Belongs to the AlaDH/PNT family.


ensembl_gene_id: HMPREF0494_0559
symbol: galK
gene_biotype: protein_coding
description:
  Galactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily.


ensembl_gene_id: HMPREF0494_0560
symbol: galT
gene_biotype: protein_coding
description:
  UTP--hexose-1-phosphate uridylyltransferase; COG: COG4468; Pfam: PF01087,PF02744; InterPro: IPR000766.


ensembl_gene_id: HMPREF0494_0564
symbol: sdaAA
gene_biotype: protein_coding
description:
  L-serine dehydratase, iron-sulfur-dependent, alpha subunit; COG: COG1760; Pfam: PF03313; InterPro: IPR004642; Belongs to the iron-sulfur dependent L-serine dehydratase family.


ensembl_gene_id: HMPREF0494_0565
symbol: sdaAB
gene_biotype: protein_coding
description:
  Putative L-serine dehydratase, iron-sulfur-dependent, beta subunit; COG: COG1760; Pfam: PF03315; InterPro: IPR005131.


ensembl_gene_id: HMPREF0494_0566
symbol: gltT
gene_biotype: protein_coding
description:
  Transporter, dicarboxylate/amino acid:cation Na+/H+ symporter family protein; COG: COG1301; Pfam: PF00375; InterPro: IPR001991; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: HMPREF0494_0571
symbol: gnd
gene_biotype: protein_coding
description:
  Phosphogluconate dehydrogenase (decarboxylating); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.


ensembl_gene_id: HMPREF0494_0573
symbol: zwf
gene_biotype: protein_coding
description:
  Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.


ensembl_gene_id: HMPREF0494_0587
symbol: ebsC
gene_biotype: protein_coding
description:
  YbaK/EbsC protein; COG: COG2606; Pfam: PF04073; InterPro: IPR007214; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.


ensembl_gene_id: HMPREF0494_0588
symbol: gntR
gene_biotype: protein_coding
description:
  UbiC transcription regulator-associated domain protein; COG: COG2188; Pfam: PF00392,PF07702; InterPro: IPR011663.


ensembl_gene_id: HMPREF0494_0591
symbol: xfp
gene_biotype: protein_coding
description:
  D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase; COG: COG3957; Pfam: PF03894; InterPro: IPR005593.


ensembl_gene_id: HMPREF0494_0592
symbol: brnQ
gene_biotype: protein_coding
description:
  Branched-chain amino acid transport system II carrier protein; Component of the transport system for branched-chain amino acids.


ensembl_gene_id: HMPREF0494_0594
symbol: fusA
gene_biotype: protein_coding
description:
  Putative translation elongation factor G; COG: COG0480; Pfam: PF00009,PF03764,PF00679; InterPro: IPR000795.


ensembl_gene_id: HMPREF0494_0612
symbol: trxB
gene_biotype: protein_coding
description:
  Pyridine nucleotide-disulfide oxidoreductase; COG: COG0492; Pfam: PF07992,PF00070; InterPro: IPR013027.


ensembl_gene_id: HMPREF0494_0613
symbol: EEW54192.1
gene_biotype: protein_coding
description:
  Serine-type D-Ala-D-Ala carboxypeptidase; COG: COG1686; Pfam: PF00768; InterPro: IPR001967; Belongs to the peptidase S11 family.


ensembl_gene_id: HMPREF0494_0615
symbol: pepQ3
gene_biotype: protein_coding
description:
  Creatinase; COG: COG0006; Pfam: PF01321,PF00557; InterPro: IPR000994; Belongs to the peptidase M24B family.


ensembl_gene_id: HMPREF0494_0617
symbol: EEW54196.1
gene_biotype: protein_coding
description:
  ABC transporter, ATP-binding protein; COG: COG3842; Pfam: PF00005,PF08402; InterPro: IPR003593; Belongs to the ABC transporter superfamily.


ensembl_gene_id: HMPREF0494_0625
symbol: czcD
gene_biotype: protein_coding
description:
  Cation diffusion facilitator family transporter; COG: COG0053; Pfam: PF01545; InterPro: IPR002524; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.


ensembl_gene_id: HMPREF0494_0631
symbol: EEW54210.1
gene_biotype: protein_coding
description:
  Gram-positive signal peptide protein, YSIRK family; Pfam: PF04650,PF06458,PF00746; InterPro: IPR005877.


ensembl_gene_id: HMPREF0494_0634
symbol: EEW54213.1
gene_biotype: protein_coding
description:
  Branched-chain amino acid ABC transporter, permease protein; COG: COG4120; Pfam: PF02653; InterPro: IPR001851; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: HMPREF0494_0638
symbol: acmC
gene_biotype: protein_coding
description:
  Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase; COG: COG1705; Pfam: PF01832; InterPro: IPR013338.


ensembl_gene_id: HMPREF0494_0648
symbol: lytS
gene_biotype: protein_coding
description:
  LytS/YhcK-type transmembrane receptor domain protein; COG: COG3275; Pfam: PF07694,PF06580,PF02518; InterPro: IPR011620.


ensembl_gene_id: HMPREF0494_0649
symbol: lytR
gene_biotype: protein_coding
description:
  Response regulator receiver domain protein; COG: COG3279; Pfam: PF00072,PF04397; InterPro: IPR001789.


ensembl_gene_id: HMPREF0494_0650
symbol: pepPN
gene_biotype: protein_coding
description:
  Proline-specific peptidase; Releases the N-terminal proline from various substrates. Belongs to the peptidase S33 family.


ensembl_gene_id: HMPREF0494_0651
symbol: EEW54230.1
gene_biotype: protein_coding
description:
  X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain protein; Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.


ensembl_gene_id: HMPREF0494_0652
symbol: potA
gene_biotype: protein_coding
description:
  Polyamine ABC transporter, ATP-binding protein; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.


ensembl_gene_id: HMPREF0494_0660
symbol: zurR
gene_biotype: protein_coding
description:
  Transcriptional regulator, Fur family; COG: COG0735; Pfam: PF01475; InterPro: IPR002481; Belongs to the Fur family.


ensembl_gene_id: HMPREF0494_0668
symbol: menB
gene_biotype: protein_coding
description:
  Naphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA).


ensembl_gene_id: HMPREF0494_0669
symbol: menE
gene_biotype: protein_coding
description:
  O-succinylbenzoate-CoA ligase; Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA (OSB-CoA); Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily.


ensembl_gene_id: HMPREF0494_0670
symbol: hflX
gene_biotype: protein_coding
description:
  GTP-binding protein HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.


ensembl_gene_id: HMPREF0494_0683
symbol: glxK
gene_biotype: protein_coding
description:
  Glycerate kinase; COG: COG1929; Pfam: PF02595; InterPro: IPR004381; Belongs to the glycerate kinase type-1 family.


ensembl_gene_id: HMPREF0494_0687
symbol: fsa
gene_biotype: protein_coding
description:
  Fructose-6-phosphate aldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.


ensembl_gene_id: HMPREF0494_0689
symbol: tkt
gene_biotype: protein_coding
description:
  Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.


ensembl_gene_id: HMPREF0494_0692
symbol: EEW54153.1
gene_biotype: protein_coding
description:
  Gram-positive signal peptide protein, YSIRK family; Pfam: PF04650,PF06458,PF00746; InterPro: IPR009459.


ensembl_gene_id: HMPREF0494_0702
symbol: scrB
gene_biotype: protein_coding
description:
  Sucrose-6-phosphate hydrolase; Enables the bacterium to metabolize sucrose as a sole carbon source; Belongs to the glycosyl hydrolase 32 family.


ensembl_gene_id: HMPREF0494_0705
symbol: EEW54047.1
gene_biotype: protein_coding
description:
  malate/L-lactate dehydrogenase; COG: COG2055; Pfam: PF02615; InterPro: IPR003767; Belongs to the LDH2/MDH2 oxidoreductase family.


ensembl_gene_id: HMPREF0494_0709
symbol: efp
gene_biotype: protein_coding
description:
  Translation elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.


ensembl_gene_id: HMPREF0494_0740
symbol: adhA
gene_biotype: protein_coding
description:
  Zinc-binding alcohol dehydrogenase family protein; COG: COG1064; Pfam: PF08240,PF00107; InterPro: IPR014187.


ensembl_gene_id: HMPREF0494_0741
symbol: EEW54083.1
gene_biotype: protein_coding
description:
  Peptidyl-prolyl cis-trans isomerase, cyclophilin-type; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.


ensembl_gene_id: HMPREF0494_0742
symbol: mleR
gene_biotype: protein_coding
description:
  LysR substrate binding domain protein; COG: COG0583; Pfam: PF00126,PF03466; InterPro: IPR005119; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: HMPREF0494_0744
symbol: fumC
gene_biotype: protein_coding
description:
  Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.


ensembl_gene_id: HMPREF0494_0745
symbol: frdA
gene_biotype: protein_coding
description:
  COG: COG1053; Pfam: PF00890; InterPro: IPR010960; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.


ensembl_gene_id: HMPREF0494_0751
symbol: citC
gene_biotype: protein_coding
description:
  [citrate (pro-3S)-lyase] ligase; Acetylation of prosthetic group (2-(5''-phosphoribosyl)-3'- dephosphocoenzyme-A) of the gamma subunit of citrate lyase.


ensembl_gene_id: HMPREF0494_0753
symbol: citE
gene_biotype: protein_coding
description:
  Citrate (pro-3S)-lyase, beta subunit; COG: COG2301; Pfam: PF03328; InterPro: IPR006475; overlaps another CDS with the same product name; Belongs to the HpcH/HpaI aldolase family.


ensembl_gene_id: HMPREF0494_0754
symbol: citF
gene_biotype: protein_coding
description:
  Citrate lyase, alpha subunit; COG: COG3051; Pfam: PF04223; InterPro: IPR006472; overlaps another CDS with the same product name.


ensembl_gene_id: HMPREF0494_0755
symbol: citG
gene_biotype: protein_coding
description:
  triphosphoribosyl-dephospho-CoA synthase CitG; COG: COG1767; Pfam: PF03802,PF01874; InterPro: IPR002736.


ensembl_gene_id: HMPREF0494_0769
symbol: mprF
gene_biotype: protein_coding
description:
  Gram-positive signal peptide protein, YSIRK family; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.


ensembl_gene_id: HMPREF0494_0770
symbol: rluD4
gene_biotype: protein_coding
description:
  Pseudouridine synthase, RluA family; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.


ensembl_gene_id: HMPREF0494_0772
symbol: lmrB3
gene_biotype: protein_coding
description:
  Drug resistance MFS transporter, drug:H+ antiporter-2 family; COG: COG0477; Pfam: PF07690; InterPro: IPR004638; Belongs to the major facilitator superfamily.


ensembl_gene_id: HMPREF0494_0775
symbol: rnj
gene_biotype: protein_coding
description:
  Hypothetical protein; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.


ensembl_gene_id: HMPREF0494_0783
symbol: sirR
gene_biotype: protein_coding
description:
  Iron dependent repressor DNA binding domain protein; COG: COG1321; Pfam: PF01325,PF02742,PF04023; InterPro: IPR001367.


ensembl_gene_id: HMPREF0494_0790
symbol: pyc
gene_biotype: protein_coding
description:
  Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.


ensembl_gene_id: HMPREF0494_0795
symbol: accC
gene_biotype: protein_coding
description:
  Putative acetyl-CoA carboxylase, biotin carboxylase subunit; COG: COG0439; Pfam: PF00289,PF02786,PF02785; InterPro: IPR013816; overlaps another CDS with the same product name.


ensembl_gene_id: HMPREF0494_0796
symbol: pxpA
gene_biotype: protein_coding
description:
  LamB/YcsF family protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.


ensembl_gene_id: HMPREF0494_0815
symbol: ctsR
gene_biotype: protein_coding
description:
  Transcriptional repressor of CtsR; COG: COG4463; Pfam: PF05848; InterPro: IPR008463; Belongs to the CtsR family.


ensembl_gene_id: HMPREF0494_0816
symbol: clpC
gene_biotype: protein_coding
description:
  ATPase family associated with various cellular activities (AAA); COG: COG0542; Pfam: PF02861,PF00004,PF02151,PF07724; InterPro: IPR003593; Belongs to the ClpA/ClpB family.


ensembl_gene_id: HMPREF0494_0818
symbol: rpoB
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: HMPREF0494_0819
symbol: rpoC
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: HMPREF0494_0822
symbol: rpsL
gene_biotype: protein_coding
description:
  Ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.


ensembl_gene_id: HMPREF0494_0823
symbol: rpsG
gene_biotype: protein_coding
description:
  Ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.


ensembl_gene_id: HMPREF0494_0824
symbol: fusA-2
gene_biotype: protein_coding
description:
  Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...]


ensembl_gene_id: HMPREF0494_0826
symbol: rpsJ
gene_biotype: protein_coding
description:
  Ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.


ensembl_gene_id: HMPREF0494_0827
symbol: rplC
gene_biotype: protein_coding
description:
  50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.


ensembl_gene_id: HMPREF0494_0829
symbol: rplW
gene_biotype: protein_coding
description:
  Ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.


ensembl_gene_id: HMPREF0494_0830
symbol: rplB
gene_biotype: protein_coding
description:
  Ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.


ensembl_gene_id: HMPREF0494_0831
symbol: rpsS
gene_biotype: protein_coding
description:
  Ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.


ensembl_gene_id: HMPREF0494_0832
symbol: rplV
gene_biotype: protein_coding
description:
  Ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.


ensembl_gene_id: HMPREF0494_0833
symbol: rpsC
gene_biotype: protein_coding
description:
  Ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.


ensembl_gene_id: HMPREF0494_0834
symbol: rplP
gene_biotype: protein_coding
description:
  Ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.


ensembl_gene_id: HMPREF0494_0835
symbol: rpmC
gene_biotype: protein_coding
description:
  Ribosomal protein L29; COG: COG0255; Pfam: PF00831; InterPro: IPR001854; Belongs to the universal ribosomal protein uL29 family.


ensembl_gene_id: HMPREF0494_0836
symbol: rpsQ
gene_biotype: protein_coding
description:
  30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.


ensembl_gene_id: HMPREF0494_0837
symbol: rplN
gene_biotype: protein_coding
description:
  Ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.


ensembl_gene_id: HMPREF0494_0838
symbol: rplX
gene_biotype: protein_coding
description:
  Ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.


ensembl_gene_id: HMPREF0494_0839
symbol: rplE
gene_biotype: protein_coding
description:
  Ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.


ensembl_gene_id: HMPREF0494_0840
symbol: rpsN
gene_biotype: protein_coding
description:
  Ribosomal protein S14p/S29e; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.


ensembl_gene_id: HMPREF0494_0841
symbol: rpsH
gene_biotype: protein_coding
description:
  Ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.


ensembl_gene_id: HMPREF0494_0842
symbol: rplF
gene_biotype: protein_coding
description:
  Ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.


ensembl_gene_id: HMPREF0494_0843
symbol: rplR
gene_biotype: protein_coding
description:
  Ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.


ensembl_gene_id: HMPREF0494_0844
symbol: rpsE
gene_biotype: protein_coding
description:
  Ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.


ensembl_gene_id: HMPREF0494_0846
symbol: rplO
gene_biotype: protein_coding
description:
  Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.


ensembl_gene_id: HMPREF0494_0847
symbol: secY
gene_biotype: protein_coding
description:
  Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.


ensembl_gene_id: HMPREF0494_0848
symbol: adk
gene_biotype: protein_coding
description:
  Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.


ensembl_gene_id: HMPREF0494_0849
symbol: infA
gene_biotype: protein_coding
description:
  Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.


ensembl_gene_id: HMPREF0494_0850
symbol: rpsM
gene_biotype: protein_coding
description:
  30S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family.


ensembl_gene_id: HMPREF0494_0851
symbol: rpsK
gene_biotype: protein_coding
description:
  30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.


ensembl_gene_id: HMPREF0494_0852
symbol: rpoA
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: HMPREF0494_0854
symbol: gadB
gene_biotype: protein_coding
description:
  Glutamate decarboxylase; COG: COG0076; Pfam: PF00282; InterPro: IPR010107; Belongs to the group II decarboxylase family.


ensembl_gene_id: HMPREF0494_0857
symbol: EEW54008.1
gene_biotype: protein_coding
description:
  Cobalt ABC transporter, ATP-binding protein; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.


ensembl_gene_id: HMPREF0494_0859
symbol: truA
gene_biotype: protein_coding
description:
  tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.


ensembl_gene_id: HMPREF0494_0860
symbol: rplM
gene_biotype: protein_coding
description:
  Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.


ensembl_gene_id: HMPREF0494_0861
symbol: rpsI
gene_biotype: protein_coding
description:
  Ribosomal protein S9; COG: COG0103; Pfam: PF00380; InterPro: IPR000754; Belongs to the universal ribosomal protein uS9 family.


ensembl_gene_id: HMPREF0494_0864
symbol: xpt
gene_biotype: protein_coding
description:
  Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.


ensembl_gene_id: HMPREF0494_0865
symbol: purK2
gene_biotype: protein_coding
description:
  ATP-grasp domain protein; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate. Belongs to the PurK/PurT family.


ensembl_gene_id: HMPREF0494_0867
symbol: ligA
gene_biotype: protein_coding
description:
  DNA ligase (NAD+); DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily.


ensembl_gene_id: HMPREF0494_0869
symbol: gatC
gene_biotype: protein_coding
description:
  aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family.


ensembl_gene_id: HMPREF0494_0870
symbol: gatA
gene_biotype: protein_coding
description:
  aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln).


ensembl_gene_id: HMPREF0494_0871
symbol: gatB
gene_biotype: protein_coding
description:
  aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily.


ensembl_gene_id: HMPREF0494_0874
symbol: rumA-2
gene_biotype: protein_coding
description:
  23S rRNA (uracil-5-)-methyltransferase RumA; COG: COG2265; Pfam: PF01938,PF08241; InterPro: IPR001566; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.


ensembl_gene_id: HMPREF0494_0878
symbol: EEW53892.1
gene_biotype: protein_coding
description:
  Resolvase, N-terminal domain protein; COG: COG1961; Pfam: PF00239,PF07508; InterPro: IPR006119; overlaps another CDS with the same product name.


ensembl_gene_id: HMPREF0494_0886
symbol: clpP
gene_biotype: protein_coding
description:
  Endopeptidase Clp; COG: COG0740; Pfam: PF00574; InterPro: IPR001907; Belongs to the peptidase S14 family.


ensembl_gene_id: HMPREF0494_0891
symbol: EEW53905.1
gene_biotype: protein_coding
description:
  DNA (cytosine-5-)-methyltransferase; COG: COG0863; Pfam: PF02195,PF01555; InterPro: IPR002941; Belongs to the N(4)/N(6)-methyltransferase family.


ensembl_gene_id: HMPREF0494_0930
symbol: casC
gene_biotype: protein_coding
description:
  CRISPR system CASCADE complex protein CasC; InterPro: IPR010148; overlaps another CDS with the same product name.


ensembl_gene_id: HMPREF0494_0931
symbol: casD
gene_biotype: protein_coding
description:
  CRISPR system CASCADE complex protein CasD; InterPro: IPR010147; overlaps another CDS with the same product name.


ensembl_gene_id: HMPREF0494_0933
symbol: cas1
gene_biotype: protein_coding
description:
  CRISPR-associated endonuclease Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.


ensembl_gene_id: HMPREF0494_0936
symbol: EEW53950.1
gene_biotype: protein_coding
description:
  Gram-positive signal peptide protein, YSIRK family; Pfam: PF04650,PF07580,PF06458,PF00746; InterPro: IPR011505.


ensembl_gene_id: HMPREF0494_0943
symbol: EEW53787.1
gene_biotype: protein_coding
description:
  Oxidoreductase, short chain dehydrogenase/reductase family protein; COG: COG1028; Pfam: PF00106; InterPro: IPR002198.


ensembl_gene_id: HMPREF0494_0945
symbol: EEW53789.1
gene_biotype: protein_coding
description:
  YbaK/proline--tRNA ligase associated domain protein; COG: COG3760; Pfam: PF04073; InterPro: IPR007214.


ensembl_gene_id: HMPREF0494_0953
symbol: rpiA
gene_biotype: protein_coding
description:
  Ribose 5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.


ensembl_gene_id: HMPREF0494_0955
symbol: dut
gene_biotype: protein_coding
description:
  dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.


ensembl_gene_id: HMPREF0494_0956
symbol: radA
gene_biotype: protein_coding
description:
  DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.


ensembl_gene_id: HMPREF0494_0958
symbol: cysS
gene_biotype: protein_coding
description:
  cysteine--tRNA ligase; COG: COG0215; Pfam: PF01406,PF09190; InterPro: IPR002308; Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: HMPREF0494_0959
symbol: cysS2
gene_biotype: protein_coding
description:
  RNase3 domain protein; Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors; Belongs to the MrnC RNase family.


ensembl_gene_id: HMPREF0494_0960
symbol: spoU
gene_biotype: protein_coding
description:
  RNA methyltransferase, TrmH family, group 3; COG: COG0566; Pfam: PF08032,PF00588; InterPro: IPR004441; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.


ensembl_gene_id: HMPREF0494_0961
symbol: rpmG
gene_biotype: protein_coding
description:
  Ribosomal protein L33; Pfam: PF00471; InterPro: IPR001705; Belongs to the bacterial ribosomal protein bL33 family.


ensembl_gene_id: HMPREF0494_0962
symbol: secE
gene_biotype: protein_coding
description:
  Preprotein translocase, SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.


ensembl_gene_id: HMPREF0494_0963
symbol: nusG
gene_biotype: protein_coding
description:
  Transcription termination/antitermination factor NusG; Participates in transcription elongation, termination and antitermination.


ensembl_gene_id: HMPREF0494_0964
symbol: rplK
gene_biotype: protein_coding
description:
  Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.


ensembl_gene_id: HMPREF0494_0965
symbol: rplA
gene_biotype: protein_coding
description:
  Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.


ensembl_gene_id: HMPREF0494_0968
symbol: rplJ
gene_biotype: protein_coding
description:
  Ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.


ensembl_gene_id: HMPREF0494_0969
symbol: rplL
gene_biotype: protein_coding
description:
  Ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family.


ensembl_gene_id: HMPREF0494_0973
symbol: cydD
gene_biotype: protein_coding
description:
  Thiol reductant ABC exporter, CydD subunit; COG: COG4988; Pfam: PF00664,PF00005; InterPro: IPR014216.


ensembl_gene_id: HMPREF0494_0975
symbol: EEW53819.1
gene_biotype: protein_coding
description:
  Polyprenyl synthetase; COG: COG0142; Pfam: PF00348; InterPro: IPR008949; Belongs to the FPP/GGPP synthase family.


ensembl_gene_id: HMPREF0494_0977
symbol: ndh
gene_biotype: protein_coding
description:
  Pyridine nucleotide-disulfide oxidoreductase; COG: COG1252; Pfam: PF01266,PF00070; InterPro: IPR001327.


ensembl_gene_id: HMPREF0494_0981
symbol: mscL
gene_biotype: protein_coding
description:
  Large conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.


ensembl_gene_id: HMPREF0494_0982
symbol: aad
gene_biotype: protein_coding
description:
  Aldehyde dehydrogenase (NAD) family protein; COG: COG1012; Pfam: PF00171,PF00465; InterPro: IPR001670; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.


ensembl_gene_id: HMPREF0494_0983
symbol: nrdF
gene_biotype: protein_coding
description:
  Ribonucleoside-diphosphate reductase, beta subunit; COG: COG0208; Pfam: PF00268; InterPro: IPR000358.


ensembl_gene_id: HMPREF0494_0984
symbol: nrdE
gene_biotype: protein_coding
description:
  Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.


ensembl_gene_id: HMPREF0494_0986
symbol: tadA
gene_biotype: protein_coding
description:
  Cytidine and deoxycytidylate deaminase zinc-binding region; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.


ensembl_gene_id: HMPREF0494_0987
symbol: dnaX
gene_biotype: protein_coding
description:
  DNA polymerase III, subunit gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.


ensembl_gene_id: HMPREF0494_0988
symbol: yaaK
gene_biotype: protein_coding
description:
  DNA-binding protein, YbaB/EbfC family; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.


ensembl_gene_id: HMPREF0494_0989
symbol: recR
gene_biotype: protein_coding
description:
  Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.


ensembl_gene_id: HMPREF0494_0991
symbol: tmk
gene_biotype: protein_coding
description:
  dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.


ensembl_gene_id: HMPREF0494_0994
symbol: EEW53838.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Involved in initiation control of chromosome replication. Belongs to the YabA family.


ensembl_gene_id: HMPREF0494_0995
symbol: rsmI
gene_biotype: protein_coding
description:
  S-adenosylmethionine-dependent methyltransferase, YraL family; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.


ensembl_gene_id: HMPREF0494_0998
symbol: ppk1
gene_biotype: protein_coding
description:
  Polyphosphate kinase 1; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family.


ensembl_gene_id: HMPREF0494_1000
symbol: galE
gene_biotype: protein_coding
description:
  UDP-glucose 4-epimerase; COG: COG1087; Pfam: PF01370; InterPro: IPR005886; Belongs to the NAD(P)-dependent epimerase/dehydratase family.


ensembl_gene_id: HMPREF0494_1003
symbol: gcp
gene_biotype: protein_coding
description:
  Putative glycoprotease GCP; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.


ensembl_gene_id: HMPREF0494_1004
symbol: proC
gene_biotype: protein_coding
description:
  Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.


ensembl_gene_id: HMPREF0494_1008
symbol: rex
gene_biotype: protein_coding
description:
  CoA binding domain protein; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.


ensembl_gene_id: HMPREF0494_1009
symbol: groS
gene_biotype: protein_coding
description:
  Chaperonin GroS; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.


ensembl_gene_id: HMPREF0494_1010
symbol: groL
gene_biotype: protein_coding
description:
  Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.


ensembl_gene_id: HMPREF0494_1017
symbol: raiA
gene_biotype: protein_coding
description:
  Ribosomal subunit interface protein; Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.


ensembl_gene_id: HMPREF0494_1018
symbol: secA
gene_biotype: protein_coding
description:
  Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.


ensembl_gene_id: HMPREF0494_1020
symbol: prfB
gene_biotype: protein_coding
description:
  Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.


ensembl_gene_id: HMPREF0494_1023
symbol: hprK
gene_biotype: protein_coding
description:
  HPr(Ser) kinase/phosphatase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable car [...]


ensembl_gene_id: HMPREF0494_1024
symbol: lgt
gene_biotype: protein_coding
description:
  Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.


ensembl_gene_id: HMPREF0494_1025
symbol: gpsA
gene_biotype: protein_coding
description:
  Glycerol-3-phosphate dehydrogenase [NAD(P)+]; COG: COG0240; Pfam: PF01210,PF07479; InterPro: IPR006168; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.


ensembl_gene_id: HMPREF0494_1028
symbol: pgm2
gene_biotype: protein_coding
description:
  Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; COG: COG1109; Pfam: PF02878,PF02879,PF02880,PF00408; InterPro: IPR016055.


ensembl_gene_id: HMPREF0494_1029
symbol: uvrB
gene_biotype: protein_coding
description:
  Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]


ensembl_gene_id: HMPREF0494_1030
symbol: uvrA
gene_biotype: protein_coding
description:
  Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.


ensembl_gene_id: HMPREF0494_1036
symbol: EEW53880.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family.


ensembl_gene_id: HMPREF0494_1038
symbol: ppsA
gene_biotype: protein_coding
description:
  Pyruvate, water dikinase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.


ensembl_gene_id: HMPREF0494_1043
symbol: clpP-2
gene_biotype: protein_coding
description:
  ATP-dependent Clp endopeptidase, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.


ensembl_gene_id: HMPREF0494_1048
symbol: gap
gene_biotype: protein_coding
description:
  Glyceraldehyde-3-phosphate dehydrogenase, type I; COG: COG0057; Pfam: PF00044,PF02800; InterPro: IPR000173; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.


ensembl_gene_id: HMPREF0494_1049
symbol: pgk
gene_biotype: protein_coding
description:
  Phosphoglycerate kinase; COG: COG0126; Pfam: PF00162; InterPro: IPR001576; Belongs to the phosphoglycerate kinase family.


ensembl_gene_id: HMPREF0494_1050
symbol: tpiA-2
gene_biotype: protein_coding
description:
  Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.


ensembl_gene_id: HMPREF0494_1051
symbol: eno
gene_biotype: protein_coding
description:
  Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.


ensembl_gene_id: HMPREF0494_1052
symbol: ptsP
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).


ensembl_gene_id: HMPREF0494_1055
symbol: secG
gene_biotype: protein_coding
description:
  Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.


ensembl_gene_id: HMPREF0494_1057
symbol: rnr
gene_biotype: protein_coding
description:
  Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.


ensembl_gene_id: HMPREF0494_1058
symbol: smpB
gene_biotype: protein_coding
description:
  SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]


ensembl_gene_id: HMPREF0494_1061
symbol: ung
gene_biotype: protein_coding
description:
  uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.


ensembl_gene_id: HMPREF0494_1068
symbol: rbsK
gene_biotype: protein_coding
description:
  Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.


ensembl_gene_id: HMPREF0494_1070
symbol: ybbP
gene_biotype: protein_coding
description:
  TIGR00159 family protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.


ensembl_gene_id: HMPREF0494_1072
symbol: glmM
gene_biotype: protein_coding
description:
  Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.


ensembl_gene_id: HMPREF0494_1073
symbol: glmS
gene_biotype: protein_coding
description:
  Glutamine-fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.


ensembl_gene_id: HMPREF0494_1082
symbol: arsC
gene_biotype: protein_coding
description:
  Arsenate reductase (thioredoxin); COG: COG0394; Pfam: PF01451; InterPro: IPR000106; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.


ensembl_gene_id: HMPREF0494_1096
symbol: nrdG
gene_biotype: protein_coding
description:
  Anaerobic ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.


ensembl_gene_id: HMPREF0494_1099
symbol: msrA
gene_biotype: protein_coding
description:
  Peptide-methionine (S)-S-oxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.


ensembl_gene_id: HMPREF0494_1105
symbol: hsp
gene_biotype: protein_coding
description:
  Hsp20/alpha crystallin family protein; COG: COG0071; Pfam: PF00011; InterPro: IPR002068; Belongs to the small heat shock protein (HSP20) family.


ensembl_gene_id: HMPREF0494_1112
symbol: metK
gene_biotype: protein_coding
description:
  Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.


ensembl_gene_id: HMPREF0494_1114
symbol: leuS
gene_biotype: protein_coding
description:
  leucine--tRNA ligase; COG: COG0495; Pfam: PF09334,PF08264; InterPro: IPR002302; Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: HMPREF0494_1117
symbol: nnrD
gene_biotype: protein_coding
description:
  YjeF domain protein; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.


ensembl_gene_id: HMPREF0494_1131
symbol: EEW53697.1
gene_biotype: protein_coding
description:
  Sigma-70 region 2; Pfam: PF04542,PF08281; InterPro: IPR014284; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: HMPREF0494_1134
symbol: thiI
gene_biotype: protein_coding
description:
  Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.


ensembl_gene_id: HMPREF0494_1135
symbol: valS
gene_biotype: protein_coding
description:
  valine--tRNA ligase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.


ensembl_gene_id: HMPREF0494_1136
symbol: folC
gene_biotype: protein_coding
description:
  Bifunctional protein FolC; COG: COG0285; Pfam: PF08245,PF02875; InterPro: IPR001645; Belongs to the folylpolyglutamate synthase family.


ensembl_gene_id: HMPREF0494_1143
symbol: aatB
gene_biotype: protein_coding
description:
  ABC transporter, substrate-binding protein, family 3; COG: COG0834; Pfam: PF00497; InterPro: IPR001638.


ensembl_gene_id: HMPREF0494_1147
symbol: pgsA
gene_biotype: protein_coding
description:
  CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; COG: COG0558; Pfam: PF01066; InterPro: IPR004570; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: HMPREF0494_1148
symbol: cinA
gene_biotype: protein_coding
description:
  Competence/damage-inducible domain protein CinA; COG: COG1058; Pfam: PF00994,PF02464; InterPro: IPR008135; Belongs to the CinA family.


ensembl_gene_id: HMPREF0494_1149
symbol: recA
gene_biotype: protein_coding
description:
  RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.


ensembl_gene_id: HMPREF0494_1151
symbol: mutS
gene_biotype: protein_coding
description:
  DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.


ensembl_gene_id: HMPREF0494_1152
symbol: mutL
gene_biotype: protein_coding
description:
  DNA mismatch repair domain protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.


ensembl_gene_id: HMPREF0494_1153
symbol: ruvA
gene_biotype: protein_coding
description:
  Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.


ensembl_gene_id: HMPREF0494_1154
symbol: ruvB
gene_biotype: protein_coding
description:
  Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.


ensembl_gene_id: HMPREF0494_1157
symbol: gnd-2
gene_biotype: protein_coding
description:
  Phosphogluconate dehydrogenase (decarboxylating); COG: COG1023; Pfam: PF03446,PF00393; InterPro: IPR004849.


ensembl_gene_id: HMPREF0494_1159
symbol: dbpA
gene_biotype: protein_coding
description:
  DEAD/DEAH box helicase; Probable DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures.


ensembl_gene_id: HMPREF0494_1160
symbol: alaS
gene_biotype: protein_coding
description:
  alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.


ensembl_gene_id: HMPREF0494_1161
symbol: EEW53727.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG: COG4472; Pfam: PF06135; InterPro: IPR009309; Belongs to the UPF0297 family.


ensembl_gene_id: HMPREF0494_1162
symbol: EEW53728.1
gene_biotype: protein_coding
description:
  RNAse H domain protein, YqgF family; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family.


ensembl_gene_id: HMPREF0494_1163
symbol: EEW53729.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG: COG3906; Pfam: PF06949; InterPro: IPR009711; Belongs to the UPF0473 family.


ensembl_gene_id: HMPREF0494_1165
symbol: mutS-2
gene_biotype: protein_coding
description:
  MutS2 family protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.


ensembl_gene_id: HMPREF0494_1175
symbol: EEW53625.1
gene_biotype: protein_coding
description:
  Site-specific recombinase, phage integrase family; Pfam: PF00589; InterPro: IPR013762; Belongs to the 'phage' integrase family.


ensembl_gene_id: HMPREF0494_1178
symbol: rdgB
gene_biotype: protein_coding
description:
  Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.


ensembl_gene_id: HMPREF0494_1182
symbol: EEW53632.1
gene_biotype: protein_coding
description:
  Transporter, small conductance mechanosensitive ion channel MscS family protein; COG: COG0668; Pfam: PF00924; InterPro: IPR006685.


ensembl_gene_id: HMPREF0494_1196
symbol: ackA
gene_biotype: protein_coding
description:
  Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.


ensembl_gene_id: HMPREF0494_1199
symbol: nagD
gene_biotype: protein_coding
description:
  HAD hydrolase, TIGR01457 family; Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro; Belongs to the HAD-like hydrolase superfamily. NagD family.


ensembl_gene_id: HMPREF0494_1233
symbol: narH
gene_biotype: protein_coding
description:
  Nitrate reductase, beta subunit; COG: COG1140; InterPro: IPR006547; overlaps another CDS with the same product name.


ensembl_gene_id: HMPREF0494_1234
symbol: narG
gene_biotype: protein_coding
description:
  Nitrate reductase, alpha subunit; COG: COG5013; Pfam: PF00384,PF01568; InterPro: IPR006468; overlaps another CDS with the same product name; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: HMPREF0494_1236
symbol: moaB
gene_biotype: protein_coding
description:
  Molybdenum cofactor synthesis domain protein; May be involved in the biosynthesis of molybdopterin. Belongs to the MoaB/Mog family.


ensembl_gene_id: HMPREF0494_1237
symbol: moeA
gene_biotype: protein_coding
description:
  Prevent-host-death family protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.


ensembl_gene_id: HMPREF0494_1238
symbol: mobB
gene_biotype: protein_coding
description:
  Molybdopterin-guanine dinucleotide biosynthesis protein B; COG: COG1763; Pfam: PF03205; InterPro: IPR004435.


ensembl_gene_id: HMPREF0494_1239
symbol: mobA
gene_biotype: protein_coding
description:
  Molybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family.


ensembl_gene_id: HMPREF0494_1242
symbol: EEW53566.1
gene_biotype: protein_coding
description:
  ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; COG: COG4585; Pfam: PF07730,PF02518; InterPro: IPR003594.


ensembl_gene_id: HMPREF0494_1251
symbol: dinJ
gene_biotype: protein_coding
description:
  Iron chelate uptake ABC transporter, FeCT family, permease protein; COG: COG0609; Pfam: PF01032; InterPro: IPR000522; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: HMPREF0494_1280
symbol: yhjE
gene_biotype: protein_coding
description:
  MFS transporter, metabolite:H+ symporter (MHS) family protein; COG: COG0477; Pfam: PF00083; InterPro: IPR005828.


ensembl_gene_id: HMPREF0494_1284
symbol: qacH
gene_biotype: protein_coding
description:
  Quaternary ammonium compound-resistance protein QacC family protein; Pfam: PF00893; InterPro: IPR000390.


ensembl_gene_id: HMPREF0494_1287
symbol: pdxB-4
gene_biotype: protein_coding
description:
  4-phosphoerythronate dehydrogenase; COG: COG0111; Pfam: PF00389,PF02826,PF01842; InterPro: IPR006139; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: HMPREF0494_1288
symbol: serC
gene_biotype: protein_coding
description:
  Putative phosphoserine transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine.


ensembl_gene_id: HMPREF0494_1289
symbol: gpmB
gene_biotype: protein_coding
description:
  Phosphoglycerate mutase family protein; COG: COG0406; Pfam: PF00300; InterPro: IPR013078; Belongs to the phosphoglycerate mutase family.


ensembl_gene_id: HMPREF0494_1305
symbol: mecA
gene_biotype: protein_coding
description:
  Negative regulator of genetic competence (MecA); Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis; Belongs to the MecA family.


ensembl_gene_id: HMPREF0494_1309
symbol: ppnK
gene_biotype: protein_coding
description:
  NAD(+)/NADH kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.


ensembl_gene_id: HMPREF0494_1314
symbol: hisK
gene_biotype: protein_coding
description:
  Histidinol phosphate phosphatase HisJ family protein; Belongs to the PHP hydrolase family. HisK subfamily.


ensembl_gene_id: HMPREF0494_1319
symbol: cspR
gene_biotype: protein_coding
description:
  RNA methyltransferase, TrmH family, group 2; Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.


ensembl_gene_id: HMPREF0494_1320
symbol: ftsK
gene_biotype: protein_coding
description:
  FtsK/SpoIIIE family protein; COG: COG1674; Pfam: PF01580; InterPro: IPR002543; Belongs to the FtsK/SpoIIIE/SftA family.


ensembl_gene_id: HMPREF0494_1324
symbol: mraW
gene_biotype: protein_coding
description:
  S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.


ensembl_gene_id: HMPREF0494_1326
symbol: pbpC
gene_biotype: protein_coding
description:
  Penicillin-binding protein, transpeptidase domain protein; COG: COG0768; Pfam: PF03717,PF00905,PF03793; InterPro: IPR001460.


ensembl_gene_id: HMPREF0494_1327
symbol: mraY
gene_biotype: protein_coding
description:
  phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.


ensembl_gene_id: HMPREF0494_1328
symbol: murD
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.


ensembl_gene_id: HMPREF0494_1329
symbol: murG
gene_biotype: protein_coding
description:
  Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.


ensembl_gene_id: HMPREF0494_1330
symbol: ftsQ
gene_biotype: protein_coding
description:
  Cell division protein FtsQ; Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex; Belongs to the FtsQ/DivIB family. DivIB subfamily.


ensembl_gene_id: HMPREF0494_1331
symbol: ftsA
gene_biotype: protein_coding
description:
  Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.


ensembl_gene_id: HMPREF0494_1332
symbol: ftsZ
gene_biotype: protein_coding
description:
  Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.


ensembl_gene_id: HMPREF0494_1333
symbol: sepF
gene_biotype: protein_coding
description:
  Hypothetical protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.


ensembl_gene_id: HMPREF0494_1337
symbol: ileS
gene_biotype: protein_coding
description:
  isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.


ensembl_gene_id: HMPREF0494_1341
symbol: mtnN
gene_biotype: protein_coding
description:
  MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.


ensembl_gene_id: HMPREF0494_1344
symbol: trmU
gene_biotype: protein_coding
description:
  tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.


ensembl_gene_id: HMPREF0494_1347
symbol: recD
gene_biotype: protein_coding
description:
  Helicase, RecD/TraA family; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily.


ensembl_gene_id: HMPREF0494_1349
symbol: dapF
gene_biotype: protein_coding
description:
  Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.


ensembl_gene_id: HMPREF0494_1350
symbol: thrA
gene_biotype: protein_coding
description:
  Aspartate kinase; COG: COG0527; Pfam: PF00696; InterPro: IPR001341; Belongs to the aspartokinase family.


ensembl_gene_id: HMPREF0494_1351
symbol: lysA
gene_biotype: protein_coding
description:
  Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.


ensembl_gene_id: HMPREF0494_1352
symbol: dapD
gene_biotype: protein_coding
description:
  2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.


ensembl_gene_id: HMPREF0494_1353
symbol: EEW53418.1
gene_biotype: protein_coding
description:
  Amidohydrolase; Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate.


ensembl_gene_id: HMPREF0494_1354
symbol: dapA
gene_biotype: protein_coding
description:
  Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).


ensembl_gene_id: HMPREF0494_1355
symbol: dapB
gene_biotype: protein_coding
description:
  Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.


ensembl_gene_id: HMPREF0494_1361
symbol: def
gene_biotype: protein_coding
description:
  Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.


ensembl_gene_id: HMPREF0494_1362
symbol: pdhA
gene_biotype: protein_coding
description:
  Pyruvate dehydrogenase E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).


ensembl_gene_id: HMPREF0494_1364
symbol: pdhC
gene_biotype: protein_coding
description:
  2-oxo acid dehydrogenase acyltransferase (catalytic domain); COG: COG0508; Pfam: PF00364,PF02817,PF00198; InterPro: IPR001078.


ensembl_gene_id: HMPREF0494_1366
symbol: EEW53431.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG: COG4476; Pfam: PF05256; InterPro: IPR007920; Belongs to the UPF0223 family.


ensembl_gene_id: HMPREF0494_1369
symbol: ftsW
gene_biotype: protein_coding
description:
  Cell cycle protein, FtsW/RodA/SpoVE family; COG: COG0772; Pfam: PF01098; InterPro: IPR001182; Belongs to the SEDS family.


ensembl_gene_id: HMPREF0494_1372
symbol: coaD
gene_biotype: protein_coding
description:
  Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.


ensembl_gene_id: HMPREF0494_1376
symbol: comEC
gene_biotype: protein_coding
description:
  DNA internalization competence protein ComEC/Rec2-like protein; COG: COG2333; Pfam: PF03772,PF00753; InterPro: IPR004797.


ensembl_gene_id: HMPREF0494_1379
symbol: rpsO
gene_biotype: protein_coding
description:
  Ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.


ensembl_gene_id: HMPREF0494_1382
symbol: tuf
gene_biotype: protein_coding
description:
  Translation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.


ensembl_gene_id: HMPREF0494_1383
symbol: tig
gene_biotype: protein_coding
description:
  Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.


ensembl_gene_id: HMPREF0494_1384
symbol: clpX
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.


ensembl_gene_id: HMPREF0494_1385
symbol: ysxC
gene_biotype: protein_coding
description:
  Ribosome biogenesis GTP-binding protein YsxC; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.


ensembl_gene_id: HMPREF0494_1387
symbol: gltX
gene_biotype: protein_coding
description:
  glutamate--tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.


ensembl_gene_id: HMPREF0494_1393
symbol: uvrC
gene_biotype: protein_coding
description:
  Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.


ensembl_gene_id: HMPREF0494_1394
symbol: cgtA
gene_biotype: protein_coding
description:
  Obg family GTPase CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.


ensembl_gene_id: HMPREF0494_1395
symbol: rnz
gene_biotype: protein_coding
description:
  Ribonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family.


ensembl_gene_id: HMPREF0494_1396
symbol: EEW53461.1
gene_biotype: protein_coding
description:
  Oxidoreductase, short chain dehydrogenase/reductase family protein; COG: COG0300; Pfam: PF00106; InterPro: IPR016040; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: HMPREF0494_1397
symbol: recJ
gene_biotype: protein_coding
description:
  single-stranded-DNA-specific exonuclease RecJ; COG: COG0608; Pfam: PF01368,PF02272; InterPro: IPR004610.


ensembl_gene_id: HMPREF0494_1398
symbol: apt
gene_biotype: protein_coding
description:
  Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.


ensembl_gene_id: HMPREF0494_1402
symbol: lexA
gene_biotype: protein_coding
description:
  Repressor LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.


ensembl_gene_id: HMPREF0494_1408
symbol: rpsB
gene_biotype: protein_coding
description:
  Ribosomal protein S2; COG: COG0052; Pfam: PF00318; InterPro: IPR005706; Belongs to the universal ribosomal protein uS2 family.


ensembl_gene_id: HMPREF0494_1409
symbol: tsf
gene_biotype: protein_coding
description:
  Translation elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.


ensembl_gene_id: HMPREF0494_1411
symbol: frr
gene_biotype: protein_coding
description:
  Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.


ensembl_gene_id: HMPREF0494_1412
symbol: uppS
gene_biotype: protein_coding
description:
  Di-trans,poly-cis-decaprenylcistransferase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.


ensembl_gene_id: HMPREF0494_1413
symbol: cdsA
gene_biotype: protein_coding
description:
  Phosphatidate cytidylyltransferase; COG: COG0575; Pfam: PF01148; InterPro: IPR000374; Belongs to the CDS family.


ensembl_gene_id: HMPREF0494_1415
symbol: proS
gene_biotype: protein_coding
description:
  proline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacy [...]


ensembl_gene_id: HMPREF0494_1416
symbol: polC
gene_biotype: protein_coding
description:
  DNA polymerase III, alpha subunit, Gram-positive type; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.


ensembl_gene_id: HMPREF0494_1417
symbol: sbcD
gene_biotype: protein_coding
description:
  Exonuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.


ensembl_gene_id: HMPREF0494_1420
symbol: rimP
gene_biotype: protein_coding
description:
  Hypothetical protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.


ensembl_gene_id: HMPREF0494_1421
symbol: nusA
gene_biotype: protein_coding
description:
  Transcription termination factor NusA; Participates in both transcription termination and antitermination.


ensembl_gene_id: HMPREF0494_1424
symbol: infB
gene_biotype: protein_coding
description:
  Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.


ensembl_gene_id: HMPREF0494_1425
symbol: rbfA
gene_biotype: protein_coding
description:
  Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.


ensembl_gene_id: HMPREF0494_1426
symbol: truB
gene_biotype: protein_coding
description:
  tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.


ensembl_gene_id: HMPREF0494_1427
symbol: ribF
gene_biotype: protein_coding
description:
  Riboflavin biosynthesis protein RibF; COG: COG0196; Pfam: PF06574,PF01687; InterPro: IPR002606; Belongs to the ribF family.


ensembl_gene_id: HMPREF0494_1429
symbol: hrcA
gene_biotype: protein_coding
description:
  Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons.


ensembl_gene_id: HMPREF0494_1430
symbol: grpE
gene_biotype: protein_coding
description:
  Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...]


ensembl_gene_id: HMPREF0494_1432
symbol: dnaJ
gene_biotype: protein_coding
description:
  Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]


ensembl_gene_id: HMPREF0494_1433
symbol: lepA
gene_biotype: protein_coding
description:
  GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.


ensembl_gene_id: HMPREF0494_1436
symbol: EEW53501.1
gene_biotype: protein_coding
description:
  Transporter, auxin efflux carrier (AEC) family protein; COG: COG0679; Pfam: PF03547; InterPro: IPR004776.


ensembl_gene_id: HMPREF0494_1441
symbol: glpF
gene_biotype: protein_coding
description:
  MIP family channel protein; COG: COG0580; Pfam: PF00230; InterPro: IPR000425; Belongs to the MIP/aquaporin (TC 1.A.8) family.


ensembl_gene_id: HMPREF0494_1445
symbol: rpsN-2
gene_biotype: protein_coding
description:
  Ribosomal protein S14p/S29e; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family.


ensembl_gene_id: HMPREF0494_1446
symbol: ahpC
gene_biotype: protein_coding
description:
  Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.


ensembl_gene_id: HMPREF0494_1451
symbol: dmpI
gene_biotype: protein_coding
description:
  4-oxalocrotonate tautomerase family enzyme; Pfam: PF01361; InterPro: IPR004370; Belongs to the 4-oxalocrotonate tautomerase family.


ensembl_gene_id: HMPREF0494_1452
symbol: glpK
gene_biotype: protein_coding
description:
  Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.


ensembl_gene_id: HMPREF0494_1457
symbol: prmA
gene_biotype: protein_coding
description:
  Ribosomal protein L11 methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family.


ensembl_gene_id: HMPREF0494_1458
symbol: EEW53372.1
gene_biotype: protein_coding
description:
  RNA methyltransferase, RsmE family; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.


ensembl_gene_id: HMPREF0494_1460
symbol: relA2
gene_biotype: protein_coding
description:
  RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.


ensembl_gene_id: HMPREF0494_1461
symbol: dtd
gene_biotype: protein_coding
description:
  D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family.


ensembl_gene_id: HMPREF0494_1462
symbol: EEW53376.1
gene_biotype: protein_coding
description:
  Phosphotransferase enzyme family; COG: COG3001; Pfam: PF01636; InterPro: IPR002575; Belongs to the fructosamine kinase family.


ensembl_gene_id: HMPREF0494_1463
symbol: aspS
gene_biotype: protein_coding
description:
  aspartate--tRNA ligase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.


ensembl_gene_id: HMPREF0494_1469
symbol: rpsU
gene_biotype: protein_coding
description:
  Ribosomal protein S21; COG: COG0828; Pfam: PF01165; InterPro: IPR001911; Belongs to the bacterial ribosomal protein bS21 family.


ensembl_gene_id: HMPREF0494_1472
symbol: argG
gene_biotype: protein_coding
description:
  Argininosuccinate synthase; COG: COG0137; Pfam: PF00764; InterPro: IPR001518; Belongs to the argininosuccinate synthase family. Type 1 subfamily.


ensembl_gene_id: HMPREF0494_1475
symbol: ybeY
gene_biotype: protein_coding
description:
  Translation metalloprotein YbeY; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.


ensembl_gene_id: HMPREF0494_1477
symbol: era
gene_biotype: protein_coding
description:
  Ribosome biogenesis GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.


ensembl_gene_id: HMPREF0494_1482
symbol: dnaG
gene_biotype: protein_coding
description:
  DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.


ensembl_gene_id: HMPREF0494_1483
symbol: rpoD
gene_biotype: protein_coding
description:
  RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.


ensembl_gene_id: HMPREF0494_1487
symbol: pepT
gene_biotype: protein_coding
description:
  Peptidase T; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family.


ensembl_gene_id: HMPREF0494_1489
symbol: dnaE
gene_biotype: protein_coding
description:
  DNA polymerase III, alpha subunit; COG: COG0587; Pfam: PF02811,PF07733,PF01336; InterPro: IPR004805.


ensembl_gene_id: HMPREF0494_1490
symbol: pyk
gene_biotype: protein_coding
description:
  Pyruvate kinase; COG: COG0469; Pfam: PF00224,PF02887; InterPro: IPR001697; Belongs to the pyruvate kinase family.


ensembl_gene_id: HMPREF0494_1492
symbol: xerD
gene_biotype: protein_coding
description:
  Phage integrase SAM-like domain protein; COG: COG4974; Pfam: PF02899,PF00589; InterPro: IPR013762; Belongs to the 'phage' integrase family.


ensembl_gene_id: HMPREF0494_1494
symbol: scpA
gene_biotype: protein_coding
description:
  ScpA/B protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.


ensembl_gene_id: HMPREF0494_1495
symbol: scpB
gene_biotype: protein_coding
description:
  Segregation and condensation protein B; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.


ensembl_gene_id: HMPREF0494_1496
symbol: rluB
gene_biotype: protein_coding
description:
  Pseudouridylate synthase; COG: COG1187; Pfam: PF01479,PF00849; InterPro: IPR000748; Belongs to the pseudouridine synthase RsuA family.


ensembl_gene_id: HMPREF0494_1497
symbol: EEW53353.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins; Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.


ensembl_gene_id: HMPREF0494_1503
symbol: der
gene_biotype: protein_coding
description:
  Ribosome biogenesis GTPase Der; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.


ensembl_gene_id: HMPREF0494_1504
symbol: hup
gene_biotype: protein_coding
description:
  DNA-binding protein HU; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.


ensembl_gene_id: HMPREF0494_1507
symbol: hpk
gene_biotype: protein_coding
description:
  ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; COG: COG0642; Pfam: PF00672,PF00512,PF02518; InterPro: IPR003594.


ensembl_gene_id: HMPREF0494_1515
symbol: EEW53306.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG: COG0667; Pfam: PF00248; InterPro: IPR001395; overlaps another CDS with the same product name; 1.1.1.91.


ensembl_gene_id: HMPREF0494_1516
symbol: EEW53307.1
gene_biotype: protein_coding
description:
  Oxidoreductase, aldo/keto reductase family protein; COG: COG0667; Pfam: PF00248; InterPro: IPR001395; overlaps another CDS with the same product name.


ensembl_gene_id: HMPREF0494_1521
symbol: moaA
gene_biotype: protein_coding
description:
  Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family.


ensembl_gene_id: HMPREF0494_1523
symbol: moaC
gene_biotype: protein_coding
description:
  Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.


ensembl_gene_id: HMPREF0494_1543
symbol: EEW53260.1
gene_biotype: protein_coding
description:
  Carboxymuconolactone decarboxylase family protein; COG: COG0599; Pfam: PF02627; InterPro: IPR003779.


ensembl_gene_id: HMPREF0494_1556
symbol: EEW53273.1
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; Pfam: PF00126; InterPro: IPR011991; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: HMPREF0494_1578
symbol: EEW53232.1
gene_biotype: protein_coding
description:
  3-beta hydroxysteroid dehydrogenase/isomerase family protein; COG: COG0702; Pfam: PF05368; InterPro: IPR016040.


ensembl_gene_id: HMPREF0494_1583
symbol: proWY
gene_biotype: protein_coding
description:
  ABC transporter, substrate-binding protein, QAT family; COG: COG1732; Pfam: PF04069; InterPro: IPR007210.


ensembl_gene_id: HMPREF0494_1587
symbol: dxs
gene_biotype: protein_coding
description:
  Putative 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.


ensembl_gene_id: HMPREF0494_1595
symbol: nemA
gene_biotype: protein_coding
description:
  Pyridine nucleotide-disulfide oxidoreductase; COG: COG1902; Pfam: PF00724,PF07992,PF00070; InterPro: IPR013785.


ensembl_gene_id: HMPREF0494_1596
symbol: EEW53250.1
gene_biotype: protein_coding
description:
  Oxidoreductase, short chain dehydrogenase/reductase family protein; Pfam: PF00106; InterPro: IPR016040.


ensembl_gene_id: HMPREF0494_1608
symbol: ubiE
gene_biotype: protein_coding
description:
  Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).


ensembl_gene_id: HMPREF0494_1615
symbol: ywlG
gene_biotype: protein_coding
description:
  TIGR01440 family protein; COG: COG4475; Pfam: PF04260; InterPro: IPR006340; Belongs to the UPF0340 family.


ensembl_gene_id: HMPREF0494_1622
symbol: EEW53192.1
gene_biotype: protein_coding
description:
  LPXTG-motif cell wall anchor domain protein; COG: COG0154; Pfam: PF01425,PF00746; InterPro: IPR000120.


ensembl_gene_id: HMPREF0494_1636
symbol: xerS
gene_biotype: protein_coding
description:
  Site-specific tyrosine recombinase XerS; COG: COG0582; Pfam: PF02899,PF00589; InterPro: IPR002104; Belongs to the 'phage' integrase family.


ensembl_gene_id: HMPREF0494_1643
symbol: EEW53213.1
gene_biotype: protein_coding
description:
  LPXTG-motif cell wall anchor domain protein; Pfam: PF04650,PF08363,PF06458,PF00746; InterPro: IPR009459.


ensembl_gene_id: HMPREF0494_1653
symbol: agl
gene_biotype: protein_coding
description:
  Glycosyl hydrolase, family 31; COG: COG1501; Pfam: PF01055; InterPro: IPR000322; Belongs to the glycosyl hydrolase 31 family.


ensembl_gene_id: HMPREF0494_1660
symbol: ilvD
gene_biotype: protein_coding
description:
  Dihydroxy-acid dehydratase; COG: COG0129; Pfam: PF00920; InterPro: IPR000581; Belongs to the IlvD/Edd family.


ensembl_gene_id: HMPREF0494_1662
symbol: gntK
gene_biotype: protein_coding
description:
  Putative gluconokinase; COG: COG1070; Pfam: PF00370,PF02782; InterPro: IPR000577; Belongs to the FGGY kinase family.


ensembl_gene_id: HMPREF0494_1665
symbol: menC
gene_biotype: protein_coding
description:
  O-succinylbenzoate synthase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB).


ensembl_gene_id: HMPREF0494_1666
symbol: aroK
gene_biotype: protein_coding
description:
  Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.


ensembl_gene_id: HMPREF0494_1667
symbol: aroA
gene_biotype: protein_coding
description:
  3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.


ensembl_gene_id: HMPREF0494_1668
symbol: aroC
gene_biotype: protein_coding
description:
  Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.


ensembl_gene_id: HMPREF0494_1670
symbol: menH
gene_biotype: protein_coding
description:
  2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Catalyzes a proton abstraction reaction that results in 2,5- elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6- hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).


ensembl_gene_id: HMPREF0494_1671
symbol: menD
gene_biotype: protein_coding
description:
  2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily.


ensembl_gene_id: HMPREF0494_1676
symbol: parC
gene_biotype: protein_coding
description:
  DNA topoisomerase IV, A subunit; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 2 subfamily.


ensembl_gene_id: HMPREF0494_1677
symbol: parE
gene_biotype: protein_coding
description:
  DNA topoisomerase IV, B subunit; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 2 subfamily.


ensembl_gene_id: HMPREF0494_1678
symbol: plsY
gene_biotype: protein_coding
description:
  Acyl-phosphate glycerol 3-phosphate acyltransferase; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.


ensembl_gene_id: HMPREF0494_1679
symbol: yfiG
gene_biotype: protein_coding
description:
  MFS transporter, SP family; COG: COG0477; Pfam: PF00083; InterPro: IPR003663; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.


ensembl_gene_id: HMPREF0494_1680
symbol: iolG
gene_biotype: protein_coding
description:
  Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase; Involved in the oxidation of myo-inositol (MI) and D-chiro- inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D- chiro-inositol (1KDCI), respectively.


ensembl_gene_id: HMPREF0494_1681
symbol: iolE
gene_biotype: protein_coding
description:
  AP endonuclease, family 2; Catalyzes the dehydration of inosose (2-keto-myo-inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D-(3,5/4)- trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi-inositol).


ensembl_gene_id: HMPREF0494_1685
symbol: idhA2
gene_biotype: protein_coding
description:
  Oxidoreductase, NAD-binding domain protein; COG: COG0673; Pfam: PF01408,PF02894; InterPro: IPR016040.


ensembl_gene_id: HMPREF0494_1690
symbol: topA
gene_biotype: protein_coding
description:
  DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]


ensembl_gene_id: HMPREF0494_1693
symbol: ylqF
gene_biotype: protein_coding
description:
  Ribosome biogenesis GTP-binding protein YlqF; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.


ensembl_gene_id: HMPREF0494_1694
symbol: EEW53138.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG: COG4479; Pfam: PF06855; InterPro: IPR010673; 3.4.16.4; Belongs to the UPF0346 family.


ensembl_gene_id: HMPREF0494_1699
symbol: folA
gene_biotype: protein_coding
description:
  Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.


ensembl_gene_id: HMPREF0494_1700
symbol: thyA
gene_biotype: protein_coding
description:
  Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.


ensembl_gene_id: HMPREF0494_1702
symbol: papS
gene_biotype: protein_coding
description:
  tRNA nucleotidyltransferase/poly(A) polymerase family protein; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.


ensembl_gene_id: HMPREF0494_1704
symbol: cysK
gene_biotype: protein_coding
description:
  Cysteine synthase A; COG: COG0031; Pfam: PF00291; InterPro: IPR005859; Belongs to the cysteine synthase/cystathionine beta- synthase family.


ensembl_gene_id: HMPREF0494_1705
symbol: metA
gene_biotype: protein_coding
description:
  Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-serine, forming acetyl-L-serine; Belongs to the MetA family.


ensembl_gene_id: HMPREF0494_1721
symbol: FbpA
gene_biotype: protein_coding
description:
  Fibronectin-binding protein A domain protein; COG: COG1293; Pfam: PF05833,PF05670; InterPro: IPR008616.


ensembl_gene_id: HMPREF0494_1723
symbol: carB
gene_biotype: protein_coding
description:
  Carbamoyl-phosphate synthetase, large subunit, oligomerization domain protein; COG: COG0458; Pfam: PF00289,PF02786,PF02787; InterPro: IPR013816.


ensembl_gene_id: HMPREF0494_1724
symbol: carA
gene_biotype: protein_coding
description:
  Carbamoyl-phosphate synthase, small subunit; COG: COG0505; Pfam: PF00988,PF00117; InterPro: IPR006274; Belongs to the CarA family.


ensembl_gene_id: HMPREF0494_1726
symbol: lspA
gene_biotype: protein_coding
description:
  Signal peptidase II; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.


ensembl_gene_id: HMPREF0494_1730
symbol: EEW53007.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG: COG0116; Pfam: PF01170; InterPro: IPR000241; Belongs to the methyltransferase superfamily.


ensembl_gene_id: HMPREF0494_1734
symbol: carB-2
gene_biotype: protein_coding
description:
  Carbamoyl-phosphate synthase, large subunit; COG: COG0458; Pfam: PF00289,PF02786,PF02787,PF02142; InterPro: IPR006275; overlaps another CDS with the same product name; Belongs to the CarB family.


ensembl_gene_id: HMPREF0494_1735
symbol: carA-2
gene_biotype: protein_coding
description:
  Carbamoyl-phosphate synthase, small subunit; COG: COG0505; Pfam: PF00988,PF00117; InterPro: IPR006274; overlaps another CDS with the same product name; Belongs to the CarA family.


ensembl_gene_id: HMPREF0494_1736
symbol: pyrC
gene_biotype: protein_coding
description:
  Amidohydrolase family protein; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.


ensembl_gene_id: HMPREF0494_1737
symbol: pyrB
gene_biotype: protein_coding
description:
  Aspartate carbamoyltransferase; COG: COG0540; Pfam: PF02729,PF00185; InterPro: IPR002082; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.


ensembl_gene_id: HMPREF0494_1739
symbol: gpsB
gene_biotype: protein_coding
description:
  DivIVA domain protein; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation.


ensembl_gene_id: HMPREF0494_1740
symbol: EEW53017.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG: COG4474; Pfam: PF06908; InterPro: IPR010697; Belongs to the UPF0398 family.


ensembl_gene_id: HMPREF0494_1741
symbol: recU
gene_biotype: protein_coding
description:
  Recombination protein U; Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation; Belongs to the RecU family.


ensembl_gene_id: HMPREF0494_1750
symbol: fni
gene_biotype: protein_coding
description:
  Isopentenyl-diphosphate delta-isomerase, type 2; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).


ensembl_gene_id: HMPREF0494_1797
symbol: xerC
gene_biotype: protein_coding
description:
  Site-specific recombinase, phage integrase family; COG: COG0582; Pfam: PF00589; InterPro: IPR013762; Belongs to the 'phage' integrase family.


ensembl_gene_id: HMPREF0494_1815
symbol: EEW53092.1
gene_biotype: protein_coding
description:
  Site-specific recombinase, phage integrase family; COG: COG0582; Pfam: PF01713,PF00589; InterPro: IPR013762; Belongs to the 'phage' integrase family.


ensembl_gene_id: HMPREF0494_1816
symbol: rplS
gene_biotype: protein_coding
description:
  Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.


ensembl_gene_id: HMPREF0494_1818
symbol: trmD
gene_biotype: protein_coding
description:
  tRNA (guanine-N(1)-)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.


ensembl_gene_id: HMPREF0494_1819
symbol: rimM
gene_biotype: protein_coding
description:
  16S rRNA processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family.


ensembl_gene_id: HMPREF0494_1821
symbol: rpsP
gene_biotype: protein_coding
description:
  Ribosomal protein S16; COG: COG0228; Pfam: PF00886; InterPro: IPR000307; Belongs to the bacterial ribosomal protein bS16 family.


ensembl_gene_id: HMPREF0494_1823
symbol: ffh
gene_biotype: protein_coding
description:
  Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.


ensembl_gene_id: HMPREF0494_1824
symbol: ylxM
gene_biotype: protein_coding
description:
  Helix-turn-helix protein, YlxM/p13 family; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.


ensembl_gene_id: HMPREF0494_1825
symbol: ftsY
gene_biotype: protein_coding
description:
  Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).


ensembl_gene_id: HMPREF0494_1826
symbol: smc
gene_biotype: protein_coding
description:
  Chromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family.


ensembl_gene_id: HMPREF0494_1827
symbol: rnc
gene_biotype: protein_coding
description:
  Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.


ensembl_gene_id: HMPREF0494_1829
symbol: plsX
gene_biotype: protein_coding
description:
  Fatty acid/phospholipid synthesis protein PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.


ensembl_gene_id: HMPREF0494_1830
symbol: recG
gene_biotype: protein_coding
description:
  ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily.


ensembl_gene_id: HMPREF0494_1833
symbol: rpmB
gene_biotype: protein_coding
description:
  Ribosomal protein L28; COG: COG0227; Pfam: PF00830; InterPro: IPR001383; Belongs to the bacterial ribosomal protein bL28 family.


ensembl_gene_id: HMPREF0494_1835
symbol: rpe
gene_biotype: protein_coding
description:
  Ribulose-phosphate 3-epimerase; COG: COG0036; Pfam: PF00834; InterPro: IPR013785; Belongs to the ribulose-phosphate 3-epimerase family.


ensembl_gene_id: HMPREF0494_1836
symbol: rsgA
gene_biotype: protein_coding
description:
  Ribosome small subunit-dependent GTPase A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.


ensembl_gene_id: HMPREF0494_1839
symbol: sun
gene_biotype: protein_coding
description:
  Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.


ensembl_gene_id: HMPREF0494_1840
symbol: fmt
gene_biotype: protein_coding
description:
  methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.


ensembl_gene_id: HMPREF0494_1841
symbol: priA
gene_biotype: protein_coding
description:
  Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.


ensembl_gene_id: HMPREF0494_1842
symbol: coaBC
gene_biotype: protein_coding
description:
  Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.


ensembl_gene_id: HMPREF0494_1843
symbol: rpoZ
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.


ensembl_gene_id: HMPREF0494_1848
symbol: tlyA
gene_biotype: protein_coding
description:
  Putative ribosomal RNA large subunit methyltransferase J; COG: COG1189; Pfam: PF01479,PF01728; InterPro: IPR004538.


ensembl_gene_id: HMPREF0494_1849
symbol: ispA
gene_biotype: protein_coding
description:
  Polyprenyl synthetase; COG: COG0142; Pfam: PF00348; InterPro: IPR000092; Belongs to the FPP/GGPP synthase family.


ensembl_gene_id: HMPREF0494_1850
symbol: xseB
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease VII, small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.


ensembl_gene_id: HMPREF0494_1851
symbol: xseA
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease VII, large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family.


ensembl_gene_id: HMPREF0494_1852
symbol: folD
gene_biotype: protein_coding
description:
  Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.


ensembl_gene_id: HMPREF0494_1853
symbol: nusB
gene_biotype: protein_coding
description:
  Transcription antitermination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.


ensembl_gene_id: HMPREF0494_1857
symbol: rpmA
gene_biotype: protein_coding
description:
  Ribosomal protein L27; COG: COG0211; Pfam: PF01016; InterPro: IPR001684; Belongs to the bacterial ribosomal protein bL27 family.


ensembl_gene_id: HMPREF0494_1859
symbol: rplU
gene_biotype: protein_coding
description:
  Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.


ensembl_gene_id: HMPREF0494_1871
symbol: miaA
gene_biotype: protein_coding
description:
  tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.


ensembl_gene_id: HMPREF0494_1877
symbol: fthC
gene_biotype: protein_coding
description:
  5-formyltetrahydrofolate cyclo-ligase; COG: COG0212; Pfam: PF01812; InterPro: IPR002698; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.


ensembl_gene_id: HMPREF0494_1878
symbol: celC
gene_biotype: protein_coding
description:
  PTS system, Lactose/Cellobiose specific IIA subunit; COG: COG1447; Pfam: PF02255; InterPro: IPR003188.


ensembl_gene_id: HMPREF0494_1879
symbol: rpmG-2
gene_biotype: protein_coding
description:
  Ribosomal protein L33; COG: COG0267; Pfam: PF00471; InterPro: IPR001705; Belongs to the bacterial ribosomal protein bL33 family.


ensembl_gene_id: HMPREF0494_1880
symbol: penA
gene_biotype: protein_coding
description:
  Penicillin-binding protein, transpeptidase domain protein; COG: COG0768; Pfam: PF03717,PF00905; InterPro: IPR001460.


ensembl_gene_id: HMPREF0494_1883
symbol: greA-2
gene_biotype: protein_coding
description:
  Prokaryotic transcription elongation factor, GreA/GreB domain protein; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.


ensembl_gene_id: HMPREF0494_1886
symbol: pheT
gene_biotype: protein_coding
description:
  phenylalanine--tRNA ligase, beta subunit; COG: COG0072; Pfam: PF01588,PF03483,PF03484,PF03147; InterPro: IPR004532; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.


ensembl_gene_id: HMPREF0494_1887
symbol: pheS
gene_biotype: protein_coding
description:
  phenylalanine--tRNA ligase, alpha subunit; COG: COG0016; Pfam: PF02912,PF01409; InterPro: IPR004529; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.


ensembl_gene_id: HMPREF0494_1890
symbol: EEW52913.1
gene_biotype: protein_coding
description:
  RNA methyltransferase, TrmH family; COG: COG0566; Pfam: PF08032,PF00588; InterPro: IPR001537; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.


ensembl_gene_id: HMPREF0494_1894
symbol: def-2
gene_biotype: protein_coding
description:
  Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins; Belongs to the polypeptide deformylase family.


ensembl_gene_id: HMPREF0494_1897
symbol: rpmF
gene_biotype: protein_coding
description:
  Ribosomal protein L32; COG: COG0333; Pfam: PF01783; InterPro: IPR002677; Belongs to the bacterial ribosomal protein bL32 family.


ensembl_gene_id: HMPREF0494_1899
symbol: tmcAL
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac- AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.


ensembl_gene_id: HMPREF0494_1901
symbol: rsfS
gene_biotype: protein_coding
description:
  Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.


ensembl_gene_id: HMPREF0494_1903
symbol: nadD
gene_biotype: protein_coding
description:
  Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).


ensembl_gene_id: HMPREF0494_1907
symbol: rplT
gene_biotype: protein_coding
description:
  Ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.


ensembl_gene_id: HMPREF0494_1908
symbol: rpmI
gene_biotype: protein_coding
description:
  Ribosomal protein L35; COG: COG0291; Pfam: PF01632; InterPro: IPR001706; Belongs to the bacterial ribosomal protein bL35 family.


ensembl_gene_id: HMPREF0494_1909
symbol: infC
gene_biotype: protein_coding
description:
  Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.


ensembl_gene_id: HMPREF0494_1910
symbol: dnaI
gene_biotype: protein_coding
description:
  Putative primosomal protein DnaI; COG: COG1484; Pfam: PF07319; InterPro: IPR009928; Belongs to the DnaA family.


ensembl_gene_id: HMPREF0494_1911
symbol: EEW52934.1
gene_biotype: protein_coding
description:
  Replication initiation and membrane attachment protein, DnaB/DnaD family; Pfam: PF07261; InterPro: IPR010833.


ensembl_gene_id: HMPREF0494_1912
symbol: iro
gene_biotype: protein_coding
description:
  Putative transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes.


ensembl_gene_id: HMPREF0494_1913
symbol: coaE
gene_biotype: protein_coding
description:
  dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.


ensembl_gene_id: HMPREF0494_1914
symbol: mutM
gene_biotype: protein_coding
description:
  DNA-formamidopyrimidine glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.


ensembl_gene_id: HMPREF0494_1915
symbol: polA
gene_biotype: protein_coding
description:
  DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.


ensembl_gene_id: HMPREF0494_1920
symbol: EEW52893.1
gene_biotype: protein_coding
description:
  tRNA binding domain protein; COG: COG0073; Pfam: PF01588; InterPro: IPR012340; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.


ensembl_gene_id: HMPREF0494_1925
symbol: trmB
gene_biotype: protein_coding
description:
  tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.


ensembl_gene_id: HMPREF0494_1930
symbol: surA
gene_biotype: protein_coding
description:
  PPIC-type PPIASE domain protein; Plays a major role in protein secretion by helping the post- translocational extracellular folding of several secreted proteins.


ensembl_gene_id: HMPREF0494_1940
symbol: rbsD
gene_biotype: protein_coding
description:
  RbsD/FucU transport family protein; Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.


ensembl_gene_id: HMPREF0494_1942
symbol: ezrA
gene_biotype: protein_coding
description:
  Septation ring formation regulator EzrA; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family.


ensembl_gene_id: HMPREF0494_1945
symbol: EEW52863.1
gene_biotype: protein_coding
description:
  Gram-positive signal peptide protein, YSIRK family; Pfam: PF04650,PF03382,PF06458,PF00746; InterPro: IPR009459.


ensembl_gene_id: HMPREF0494_1946
symbol: pntB
gene_biotype: protein_coding
description:
  NAD(P) transhydrogenase beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.


ensembl_gene_id: HMPREF0494_1948
symbol: pntAA
gene_biotype: protein_coding
description:
  Putative NAD(P)(+) transhydrogenase (AB-specific), alpha subunit; COG: COG3288; Pfam: PF05222,PF01262; InterPro: IPR016040.


ensembl_gene_id: HMPREF0494_1949
symbol: EEW52867.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG: COG3022; Pfam: PF03883; InterPro: IPR005583; Belongs to the UPF0246 family.


ensembl_gene_id: HMPREF0494_1962
symbol: abf
gene_biotype: protein_coding
description:
  Glycosyl hydrolase, family 43; COG: COG3940; Pfam: PF04616; InterPro: IPR006710; Belongs to the glycosyl hydrolase 43 family.


ensembl_gene_id: HMPREF0494_1965
symbol: EEW52883.1
gene_biotype: protein_coding
description:
  3-hydroxyacyl-CoA dehydrogenase, NAD binding domain protein; COG: COG1250; Pfam: PF02737,PF00725; InterPro: IPR016040.


ensembl_gene_id: HMPREF0494_1969
symbol: ddlA
gene_biotype: protein_coding
description:
  D-ala D-ala ligase N-terminal domain protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.


ensembl_gene_id: HMPREF0494_1977
symbol: atpC
gene_biotype: protein_coding
description:
  ATP synthase F1, epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane.


ensembl_gene_id: HMPREF0494_1978
symbol: atpD
gene_biotype: protein_coding
description:
  ATP synthase F1, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.


ensembl_gene_id: HMPREF0494_1979
symbol: atpG
gene_biotype: protein_coding
description:
  ATP synthase F1, gamma subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.


ensembl_gene_id: HMPREF0494_1980
symbol: atpA
gene_biotype: protein_coding
description:
  ATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.


ensembl_gene_id: HMPREF0494_1981
symbol: atpH
gene_biotype: protein_coding
description:
  ATP synthase F1, delta subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.


ensembl_gene_id: HMPREF0494_1982
symbol: atpF
gene_biotype: protein_coding
description:
  ATP synthase F0, B subunit; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family.


ensembl_gene_id: HMPREF0494_1983
symbol: atpE
gene_biotype: protein_coding
description:
  ATP synthase F0, C subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.


ensembl_gene_id: HMPREF0494_1984
symbol: atpB
gene_biotype: protein_coding
description:
  ATP synthase F0, A subunit; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family.


ensembl_gene_id: HMPREF0494_1985
symbol: EEW52816.1
gene_biotype: protein_coding
description:
  YibE/F-like protein; Pfam: PF07907; InterPro: IPR012507; overlaps another CDS with the same product name.


ensembl_gene_id: HMPREF0494_1986
symbol: EEW52817.1
gene_biotype: protein_coding
description:
  YibE/F-like protein; COG: COG5438; Pfam: PF07907; InterPro: IPR012507; overlaps another CDS with the same product name.


ensembl_gene_id: HMPREF0494_1987
symbol: upp
gene_biotype: protein_coding
description:
  Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.


ensembl_gene_id: HMPREF0494_1988
symbol: EEW52819.1
gene_biotype: protein_coding
description:
  Sua5/YciO/YrdC/YwlC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.


ensembl_gene_id: HMPREF0494_1989
symbol: prmC
gene_biotype: protein_coding
description:
  protein-(glutamine-N5) methyltransferase, release factor-specific; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.


ensembl_gene_id: HMPREF0494_1990
symbol: prfA
gene_biotype: protein_coding
description:
  Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.


ensembl_gene_id: HMPREF0494_2004
symbol: glxR
gene_biotype: protein_coding
description:
  Phosphogluconate dehydrogenase (decarboxylating), NAD binding domain protein; COG: COG2084; Pfam: PF03446; InterPro: IPR015815.


ensembl_gene_id: HMPREF0494_2013
symbol: EEW52844.1
gene_biotype: protein_coding
description:
  Glycosyl hydrolase family 3 N-terminal domain protein; COG: COG1472; Pfam: PF00933,PF01915; InterPro: IPR002772; Belongs to the glycosyl hydrolase 3 family.


ensembl_gene_id: HMPREF0494_2014
symbol: EEW52845.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG: COG2730; InterPro: IPR013781; Belongs to the glycosyl hydrolase 5 (cellulase A) family.


ensembl_gene_id: HMPREF0494_2016
symbol: EEW52847.1
gene_biotype: protein_coding
description:
  Beta-galactosidase trimerization domain protein; Pfam: PF02449,PF08532,PF08533; InterPro: IPR013781.


ensembl_gene_id: HMPREF0494_2018
symbol: xynA
gene_biotype: protein_coding
description:
  Glycosyl hydrolase, family 43; COG: COG3507; Pfam: PF04616; InterPro: IPR006710; Belongs to the glycosyl hydrolase 43 family.


ensembl_gene_id: HMPREF0494_2022
symbol: xylA
gene_biotype: protein_coding
description:
  Xylose isomerase; COG: COG2115; Pfam: PF01261; InterPro: IPR013022; Belongs to the xylose isomerase family.


ensembl_gene_id: HMPREF0494_2032
symbol: pgi-2
gene_biotype: protein_coding
description:
  Glucose-6-phosphate isomerase; COG: COG0166; Pfam: PF00342; InterPro: IPR001672; Belongs to the GPI family.


ensembl_gene_id: HMPREF0494_2045
symbol: EEW52760.1
gene_biotype: protein_coding
description:
  Drug resistance MFS transporter, drug:H+ antiporter-2 family; Pfam: PF07690; InterPro: IPR004638; Belongs to the major facilitator superfamily.


ensembl_gene_id: HMPREF0494_2068
symbol: EEW52783.1
gene_biotype: protein_coding
description:
  Glycosyltransferase, group 1 family protein; COG: COG0438; Pfam: PF09318,PF00534; InterPro: IPR015397.


ensembl_gene_id: HMPREF0494_2081
symbol: tpx
gene_biotype: protein_coding
description:
  Redoxin family protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.


ensembl_gene_id: HMPREF0494_2082
symbol: cpsY
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; COG: COG0583; Pfam: PF00126; InterPro: IPR011991; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: HMPREF0494_2083
symbol: metE
gene_biotype: protein_coding
description:
  5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.


ensembl_gene_id: HMPREF0494_2084
symbol: metF
gene_biotype: protein_coding
description:
  Methylenetetrahydrofolate reductase (NAD(P)H); COG: COG0685; Pfam: PF02219; InterPro: IPR003171; Belongs to the methylenetetrahydrofolate reductase family.


ensembl_gene_id: HMPREF0494_2097
symbol: gltX2
gene_biotype: protein_coding
description:
  Plasma-membrane proton-efflux P-type ATPase; COG: COG0474; Pfam: PF00690,PF00122,PF00702; InterPro: IPR006534.


ensembl_gene_id: HMPREF0494_2100
symbol: racD
gene_biotype: protein_coding
description:
  Aspartate racemase; COG: COG1794; Pfam: PF01177; InterPro: IPR004380; Belongs to the aspartate/glutamate racemases family.


ensembl_gene_id: HMPREF0494_2104
symbol: nadE
gene_biotype: protein_coding
description:
  NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family.


ensembl_gene_id: HMPREF0494_2106
symbol: EEW52684.1
gene_biotype: protein_coding
description:
  Metallopeptidase, SprT family; COG: COG3091; Pfam: PF03926; InterPro: IPR006640; Belongs to the SprT family.


ensembl_gene_id: HMPREF0494_2108
symbol: hemG
gene_biotype: protein_coding
description:
  Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.


ensembl_gene_id: HMPREF0494_2109
symbol: hemG2
gene_biotype: protein_coding
description:
  Protoporphyrinogen oxidase domain protein; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.


ensembl_gene_id: HMPREF0494_2110
symbol: EEW52688.1
gene_biotype: protein_coding
description:
  Glycosyl hydrolase family 2, TIM barrel domain protein; COG: COG3250; Pfam: PF02837,PF00703,PF02836; InterPro: IPR006103.


ensembl_gene_id: HMPREF0494_2111
symbol: EEW52689.1
gene_biotype: protein_coding
description:
  Beta galactosidase small chain; Pfam: PF02929; InterPro: IPR014718; overlaps another CDS with the same product name.


ensembl_gene_id: HMPREF0494_2112
symbol: lacM
gene_biotype: protein_coding
description:
  Tat pathway signal sequence domain protein; Pfam: PF02929; InterPro: IPR014718; overlaps another CDS with the same product name.


ensembl_gene_id: HMPREF0494_2117
symbol: ogt
gene_biotype: protein_coding
description:
  6-O-methylguanine DNA methyltransferase, DNA binding domain protein; Pfam: PF01035; InterPro: IPR014048.


ensembl_gene_id: HMPREF0494_2119
symbol: hicD4
gene_biotype: protein_coding
description:
  Lactate/malate dehydrogenase, NAD binding domain protein; Pfam: PF02254,PF02866; InterPro: IPR015955; Belongs to the LDH/MDH superfamily.


ensembl_gene_id: HMPREF0494_2120
symbol: EEW52698.1
gene_biotype: protein_coding
description:
  TIGR00730 family protein; COG: COG1611; Pfam: PF03641; InterPro: IPR005269; Belongs to the LOG family.


ensembl_gene_id: HMPREF0494_2124
symbol: mnaA
gene_biotype: protein_coding
description:
  UDP-N-acetylglucosamine 2-epimerase; COG: COG0381; Pfam: PF02350; InterPro: IPR003331; Belongs to the UDP-N-acetylglucosamine 2-epimerase family.


ensembl_gene_id: HMPREF0494_2128
symbol: map-2
gene_biotype: protein_coding
description:
  Methionine aminopeptidase, type I; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.


ensembl_gene_id: HMPREF0494_2163
symbol: rfbA
gene_biotype: protein_coding
description:
  Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.


ensembl_gene_id: HMPREF0494_2164
symbol: rfbC
gene_biotype: protein_coding
description:
  dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.


ensembl_gene_id: HMPREF0494_2165
symbol: rfbB
gene_biotype: protein_coding
description:
  dTDP-glucose 4,6-dehydratase; COG: COG1088; Pfam: PF01370; InterPro: IPR005888; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.


ensembl_gene_id: HMPREF0494_2166
symbol: rfbD
gene_biotype: protein_coding
description:
  dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.


ensembl_gene_id: HMPREF0494_2174
symbol: prfC
gene_biotype: protein_coding
description:
  Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.


ensembl_gene_id: HMPREF0494_2194
symbol: EEW52626.1
gene_biotype: protein_coding
description:
  Permease, cytosine/purine, uracil, thiamine, allantoin family; Pfam: PF02133; InterPro: IPR001248; Belongs to the purine-cytosine permease (2.A.39) family.


ensembl_gene_id: HMPREF0494_2195
symbol: EEW52627.1
gene_biotype: protein_coding
description:
  Kinase, PfkB family; COG: COG0524; Pfam: PF00294; InterPro: IPR011611; Belongs to the carbohydrate kinase PfkB family.


ensembl_gene_id: HMPREF0494_2209
symbol: clpE
gene_biotype: protein_coding
description:
  ATPase family associated with various cellular activities (AAA); COG: COG0542; Pfam: PF00004,PF02151,PF07724; InterPro: IPR003593; Belongs to the ClpA/ClpB family.


ensembl_gene_id: HMPREF0494_2216
symbol: mprF-2
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.


# pathwayInfo

id: CL:100
description: Structural constituent of ribosome
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:100_Structural_constituent_of_ribosome


id: CL:1001
description: Mixed, incl. RNA (guanine-N7)-methylation, and Establishment of competence for transformation
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1001_Mixed,_incl._RNA_(guanine-N7)-methylation,_and_Establishment_of_competence_for_transformation


id: CL:1010
description: Mixed, incl. Enzyme binding, and HesB-like domain superfamily
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1010_Mixed,_incl._Enzyme_binding,_and_HesB-like_domain_superfamily


id: CL:102
description: Structural constituent of ribosome
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:102_Structural_constituent_of_ribosome


id: CL:1023
description: Mixed, incl. Phosphorus-oxygen lyase activity, and Positive regulation of molecular function
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1023_Mixed,_incl._Phosphorus-oxygen_lyase_activity,_and_Positive_regulation_of_molecular_function


id: CL:103
description: Structural constituent of ribosome
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:103_Structural_constituent_of_ribosome


id: CL:1034
description: Mixed, incl. Sulfur relay system, and Nicotinamide nucleotide metabolic process
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1034_Mixed,_incl._Sulfur_relay_system,_and_Nicotinamide_nucleotide_metabolic_process


id: CL:1035
description: Mixed, incl. Nicotinamide nucleotide metabolic process, and Cold shock, CspA
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1035_Mixed,_incl._Nicotinamide_nucleotide_metabolic_process,_and_Cold_shock,_CspA


id: CL:1037
description: Mixed, incl. Cold shock, CspA, and Nucleoside catabolic process
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1037_Mixed,_incl._Cold_shock,_CspA,_and_Nucleoside_catabolic_process


id: CL:1058
description: Mixed, incl. THUMP domain, and Transcription regulator Rrf2
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1058_Mixed,_incl._THUMP_domain,_and_Transcription_regulator_Rrf2


id: CL:1067
description: Mixed, incl. Chromosome segregation, and Alditol metabolic process
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1067_Mixed,_incl._Chromosome_segregation,_and_Alditol_metabolic_process


id: CL:1069
description: Mixed, incl. Chromosome segregation, and RecQ zinc-binding
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1069_Mixed,_incl._Chromosome_segregation,_and_RecQ_zinc-binding


id: CL:1071
description: Mixed, incl. Chromosome partition, and rRNA pseudouridine synthesis
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1071_Mixed,_incl._Chromosome_partition,_and_rRNA_pseudouridine_synthesis


id: CL:1095
description: Mixed, incl. Alditol metabolic process, and SGNH hydrolase-type esterase domain
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1095_Mixed,_incl._Alditol_metabolic_process,_and_SGNH_hydrolase-type_esterase_domain


id: CL:1098
description: Mixed, incl. SGNH hydrolase-type esterase domain, and RNA-DNA hybrid ribonuclease activity
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1098_Mixed,_incl._SGNH_hydrolase-type_esterase_domain,_and_RNA-DNA_hybrid_ribonuclease_activity


id: CL:1109
description: Alditol metabolic process, and Alkaline shock protein Asp23
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1109_Alditol_metabolic_process,_and_Alkaline_shock_protein_Asp23


id: CL:1118
description: Mostly uncharacterized, incl. Cell surface, and Response to heat
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1118_Mostly_uncharacterized,_incl._Cell_surface,_and_Response_to_heat


id: CL:1120
description: Mixed, incl. Cell surface, and Response to heat
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1120_Mixed,_incl._Cell_surface,_and_Response_to_heat


id: CL:1144
description: Mixed, incl. tRNA threonylcarbamoyladenosine modification, and Protein of unknown function DUF2252
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1144_Mixed,_incl._tRNA_threonylcarbamoyladenosine_modification,_and_Protein_of_unknown_function_DUF2252


id: CL:1145
description: Mixed, incl. tRNA threonylcarbamoyladenosine modification, and Bacterial nucleoid
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1145_Mixed,_incl._tRNA_threonylcarbamoyladenosine_modification,_and_Bacterial_nucleoid


id: CL:1148
description: Bacterial nucleoid, and dTTP metabolic process
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1148_Bacterial_nucleoid,_and_dTTP_metabolic_process


id: CL:1168
description: Protein of unknown function DUF2252, and Exopolyphosphatase activity
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1168_Protein_of_unknown_function_DUF2252,_and_Exopolyphosphatase_activity


id: CL:1180
description: Mixed, incl. Establishment of competence for transformation, and Coenzyme A biosynthesis
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1180_Mixed,_incl._Establishment_of_competence_for_transformation,_and_Coenzyme_A_biosynthesis


id: CL:1181
description: Mixed, incl. Establishment of competence for transformation, and HAD superfamily
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1181_Mixed,_incl._Establishment_of_competence_for_transformation,_and_HAD_superfamily


id: CL:1183
description: Mixed, incl. Establishment of competence for transformation, and Pilin-like
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1183_Mixed,_incl._Establishment_of_competence_for_transformation,_and_Pilin-like


id: CL:1185
description: Establishment of competence for transformation, and Pilin-like
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1185_Establishment_of_competence_for_transformation,_and_Pilin-like


id: CL:1201
description: Mixed, incl. Nucleotidyltransferase
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1201_Mixed,_incl._Nucleotidyltransferase


id: CL:1224
description: Mixed, incl. Coenzyme A biosynthesis, and Peptide deformylase
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1224_Mixed,_incl._Coenzyme_A_biosynthesis,_and_Peptide_deformylase


id: CL:1226
description: Mixed, incl. Protein catabolic process, and Coenzyme A biosynthesis
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1226_Mixed,_incl._Protein_catabolic_process,_and_Coenzyme_A_biosynthesis


id: CL:1246
description: Mixed, incl. Nicotinate and nicotinamide metabolism, and Isochorismatase-like
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1246_Mixed,_incl._Nicotinate_and_nicotinamide_metabolism,_and_Isochorismatase-like


id: CL:1247
description: Nicotinate and nicotinamide metabolism, and Isochorismatase-like
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1247_Nicotinate_and_nicotinamide_metabolism,_and_Isochorismatase-like


id: CL:1248
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1248_Mixed,_incl._DHS-like_NAD/FAD-binding_domain_superfamily,_and_Nicotinamide_nucleotide_biosynthetic_process

description:
  Mixed, incl. DHS-like NAD/FAD-binding domain superfamily, and Nicotinamide nucleotide biosynthetic process


id: CL:1249
description: Nicotinate and nicotinamide metabolism
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1249_Nicotinate_and_nicotinamide_metabolism


id: CL:1260
description: Protein deacylation, and PepSY domain
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1260_Protein_deacylation,_and_PepSY_domain


id: CL:1269
description: Mixed, incl. Nicotinamidase activity, and Nicotinate phosphoribosyltransferase family
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1269_Mixed,_incl._Nicotinamidase_activity,_and_Nicotinate_phosphoribosyltransferase_family


id: CL:1278
description: Mixed, incl. Cytidylyltransferase-like, and HDIG domain
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1278_Mixed,_incl._Cytidylyltransferase-like,_and_HDIG_domain


id: CL:1281
description: NAD biosynthetic process, and RNA capping
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1281_NAD_biosynthetic_process,_and_RNA_capping


id: CL:1303
description: Mixed, incl. Microbial metabolism in diverse environments, and Small molecule biosynthetic process
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1303_Mixed,_incl._Microbial_metabolism_in_diverse_environments,_and_Small_molecule_biosynthetic_process


id: CL:1304
description: Mixed, incl. Microbial metabolism in diverse environments, and Small molecule biosynthetic process
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1304_Mixed,_incl._Microbial_metabolism_in_diverse_environments,_and_Small_molecule_biosynthetic_process


id: CL:1305
description: Mixed, incl. Microbial metabolism in diverse environments, and Small molecule biosynthetic process
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1305_Mixed,_incl._Microbial_metabolism_in_diverse_environments,_and_Small_molecule_biosynthetic_process


id: CL:1306
description: Mixed, incl. Microbial metabolism in diverse environments, and Lipid biosynthesis
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1306_Mixed,_incl._Microbial_metabolism_in_diverse_environments,_and_Lipid_biosynthesis


id: CL:1307
description: Mixed, incl. Microbial metabolism in diverse environments, and Lipid biosynthesis
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1307_Mixed,_incl._Microbial_metabolism_in_diverse_environments,_and_Lipid_biosynthesis


id: CL:1309
description: Glycolysis / Gluconeogenesis, and Oxidoreductase activity
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1309_Glycolysis_/_Gluconeogenesis,_and_Oxidoreductase_activity


id: CL:1310
description: Mixed, incl. Glycolysis / Gluconeogenesis, and FAD/NAD(P)-binding domain superfamily
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1310_Mixed,_incl._Glycolysis_/_Gluconeogenesis,_and_FAD/NAD(P)-binding_domain_superfamily


id: CL:1311
description: Mixed, incl. Glycolysis / Gluconeogenesis, and FAD/NAD(P)-binding domain superfamily
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1311_Mixed,_incl._Glycolysis_/_Gluconeogenesis,_and_FAD/NAD(P)-binding_domain_superfamily


id: CL:1313
description: Glycolysis / Gluconeogenesis, and Tyrosine metabolism
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1313_Glycolysis_/_Gluconeogenesis,_and_Tyrosine_metabolism


id: CL:1314
description: Glycolysis / Gluconeogenesis, and Aldehyde-lyase activity
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1314_Glycolysis_/_Gluconeogenesis,_and_Aldehyde-lyase_activity


id: CL:1315
description: Mixed, incl. L-lactate/malate dehydrogenase, and Citrate cycle (TCA cycle)
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1315_Mixed,_incl._L-lactate/malate_dehydrogenase,_and_Citrate_cycle_(TCA_cycle)


id: CL:1317
description: L-lactate dehydrogenase, active site, and Fermentation
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1317_L-lactate_dehydrogenase,_active_site,_and_Fermentation


id: CL:1335
description: Citrate cycle (TCA cycle), and Aldehyde dehydrogenase family
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1335_Citrate_cycle_(TCA_cycle),_and_Aldehyde_dehydrogenase_family


id: CL:1347
description: Glycolysis, and Aldehyde-lyase activity
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1347_Glycolysis,_and_Aldehyde-lyase_activity


id: CL:1349
description: Triosephosphate isomerase, and Phosphotransferase activity, carboxyl group as acceptor
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1349_Triosephosphate_isomerase,_and_Phosphotransferase_activity,_carboxyl_group_as_acceptor


id: CL:136
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:136_Mixed,_incl._Translation_elongation_factor_EF1A/initiation_factor_IF2gamma,_C-terminal,_and_Small_ribosomal_subunit

description:
  Mixed, incl. Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal, and Small ribosomal subunit


id: CL:1363
description: Phosphoglycerate mutase 1, and Transketolase or transaldolase activity
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1363_Phosphoglycerate_mutase_1,_and_Transketolase_or_transaldolase_activity


id: CL:1375
description: Tyrosine metabolism, and Taurine and hypotaurine metabolism
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1375_Tyrosine_metabolism,_and_Taurine_and_hypotaurine_metabolism


id: CL:1399
description: FAD/NAD(P)-binding domain, and Thioredoxin domain
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1399_FAD/NAD(P)-binding_domain,_and_Thioredoxin_domain


id: CL:1419
description: Mixed, incl. Lipoyl, and Lipoic acid metabolism
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1419_Mixed,_incl._Lipoyl,_and_Lipoic_acid_metabolism


id: CL:1436
description: Phosphotransferase system, and Sodium:galactoside symporter, conserved site
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1436_Phosphotransferase_system,_and_Sodium:galactoside_symporter,_conserved_site


id: CL:1449
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1449_Mixed,_incl._Short-chain_dehydrogenase/reductase_SDR,_and_Poly(ribitol_phosphate)_teichoic_acid_metabolic_process

description:
  Mixed, incl. Short-chain dehydrogenase/reductase SDR, and Poly(ribitol phosphate) teichoic acid metabolic process


id: CL:1451
description: Ketone catabolic process, and Acetoin reductase
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1451_Ketone_catabolic_process,_and_Acetoin_reductase


id: CL:1477
description: Mixed, incl. Lipid biosynthesis, and Fatty acid metabolic process
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1477_Mixed,_incl._Lipid_biosynthesis,_and_Fatty_acid_metabolic_process


id: CL:1479
description: Mixed, incl. Fatty acid metabolism, and Thioesterase domain
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1479_Mixed,_incl._Fatty_acid_metabolism,_and_Thioesterase_domain


id: CL:1480
description: Fatty acid metabolism, and Biotin-protein ligase activity
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1480_Fatty_acid_metabolism,_and_Biotin-protein_ligase_activity


id: CL:1481
description: Fatty acid metabolism, and Biotin-protein ligase activity
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1481_Fatty_acid_metabolism,_and_Biotin-protein_ligase_activity


id: CL:1483
description: Fatty acid synthase activity, and CoA carboxylase activity
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1483_Fatty_acid_synthase_activity,_and_CoA_carboxylase_activity


id: CL:1484
description: CoA carboxylase activity, and FabA-like domain
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1484_CoA_carboxylase_activity,_and_FabA-like_domain


id: CL:1514
description: Cyclophilin-like domain superfamily, and CoA carboxylase activity
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1514_Cyclophilin-like_domain_superfamily,_and_CoA_carboxylase_activity


id: CL:1525
description: Thioesterase domain, and Menaquinone biosynthesis
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1525_Thioesterase_domain,_and_Menaquinone_biosynthesis


id: CL:1538
description: Phospholipid metabolism, and O-acyltransferase activity
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1538_Phospholipid_metabolism,_and_O-acyltransferase_activity


id: CL:1558
description: Branched-chain amino acid biosynthesis, and Secondary alcohol metabolic process
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1558_Branched-chain_amino_acid_biosynthesis,_and_Secondary_alcohol_metabolic_process


id: CL:1573
description: Biosynthesis of amino acids, and Alanine, aspartate and glutamate metabolism
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1573_Biosynthesis_of_amino_acids,_and_Alanine,_aspartate_and_glutamate_metabolism


id: CL:1574
description: Biosynthesis of amino acids, and Alanine, aspartate and glutamate metabolism
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1574_Biosynthesis_of_amino_acids,_and_Alanine,_aspartate_and_glutamate_metabolism


id: CL:1575
description: Lysine biosynthesis, and Alanine, aspartate and glutamate metabolism
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1575_Lysine_biosynthesis,_and_Alanine,_aspartate_and_glutamate_metabolism


id: CL:1576
description: Diaminopimelate metabolic process, and Alanine, aspartate and glutamate metabolism
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1576_Diaminopimelate_metabolic_process,_and_Alanine,_aspartate_and_glutamate_metabolism


id: CL:1578
description: Alanine, aspartate and glutamate metabolism
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1578_Alanine,_aspartate_and_glutamate_metabolism


id: CL:159
description: Mixed, incl. Ribosomal protein S13-like, H2TH, and K Homology domain, type 2
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:159_Mixed,_incl._Ribosomal_protein_S13-like,_H2TH,_and_K_Homology_domain,_type_2


id: CL:1613
description: Aminotransferase, class I/classII, and UDP-N-acetylglucosamine metabolic process
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1613_Aminotransferase,_class_I/classII,_and_UDP-N-acetylglucosamine_metabolic_process


id: CL:1622
description: Cysteine and methionine metabolism, and Phosphoglycerate mutase family
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1622_Cysteine_and_methionine_metabolism,_and_Phosphoglycerate_mutase_family


id: CL:1623
description: L-serine metabolic process, and Ammonia-lyase activity
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1623_L-serine_metabolic_process,_and_Ammonia-lyase_activity


id: CL:1626
description: Ammonia-lyase activity, and Cysteine biosynthesis
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1626_Ammonia-lyase_activity,_and_Cysteine_biosynthesis


id: CL:1643
description: UROD/MetE-like superfamily, and One-carbon metabolic process
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1643_UROD/MetE-like_superfamily,_and_One-carbon_metabolic_process


id: CL:1656
description: Phenylalanine, tyrosine and tryptophan biosynthesis, and Menaquinone biosynthesis
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1656_Phenylalanine,_tyrosine_and_tryptophan_biosynthesis,_and_Menaquinone_biosynthesis


id: CL:1674
description: Mixed, incl. LacY/RafB permease family, and Transcriptional regulator LacI/GalR-like, sensor domain
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1674_Mixed,_incl._LacY/RafB_permease_family,_and_Transcriptional_regulator_LacI/GalR-like,_sensor_domain


id: CL:1683
description: Mixed, incl. Oxo-acid-lyase activity, and Fermentation
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1683_Mixed,_incl._Oxo-acid-lyase_activity,_and_Fermentation


id: CL:1688
description: Oxo-acid-lyase activity, and Acyl carrier activity
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1688_Oxo-acid-lyase_activity,_and_Acyl_carrier_activity


id: CL:1702
description: Mixed, incl. Galactose metabolism, and Carbohydrate metabolic process
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1702_Mixed,_incl._Galactose_metabolism,_and_Carbohydrate_metabolic_process


id: CL:1703
description: Mixed, incl. Galactose metabolism, and Carbohydrate metabolism
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1703_Mixed,_incl._Galactose_metabolism,_and_Carbohydrate_metabolism


id: CL:1704
description: Galactose metabolism, and Amino sugar metabolic process
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1704_Galactose_metabolism,_and_Amino_sugar_metabolic_process


id: CL:1705
description: Galactose metabolism, and PspC domain
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1705_Galactose_metabolism,_and_PspC_domain


id: CL:1707
description: Beta-galactosidase complex, and Galactose metabolic process
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1707_Beta-galactosidase_complex,_and_Galactose_metabolic_process


id: CL:1717
description: Galactose metabolic process, and Aldose 1-epimerase
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1717_Galactose_metabolic_process,_and_Aldose_1-epimerase


id: CL:1732
description: Mixed, incl. Glycosyl hydrolase, all-beta, and Oligo-1,6-glucosidase, domain 2
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1732_Mixed,_incl._Glycosyl_hydrolase,_all-beta,_and_Oligo-1,6-glucosidase,_domain_2


id: CL:175
description: rRNA-binding, and Translation elongation factor activity
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:175_rRNA-binding,_and_Translation_elongation_factor_activity


id: CL:1751
description: Mixed, incl. Amino sugar metabolic process, and ROK family
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1751_Mixed,_incl._Amino_sugar_metabolic_process,_and_ROK_family


id: CL:1753
description: Amino sugar catabolic process, and SIS domain
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1753_Amino_sugar_catabolic_process,_and_SIS_domain


id: CL:1767
description: Mixed, incl. DapA-like, and Prolyl oligopeptidase family
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1767_Mixed,_incl._DapA-like,_and_Prolyl_oligopeptidase_family


id: CL:1779
description: Mixed, incl. Pentose-phosphate shunt, and Carbohydrate kinase, FGGY
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1779_Mixed,_incl._Pentose-phosphate_shunt,_and_Carbohydrate_kinase,_FGGY


id: CL:178
description: rRNA-binding, and Ribosomal protein L2, domain 2
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:178_rRNA-binding,_and_Ribosomal_protein_L2,_domain_2


id: CL:1781
description: Mixed, incl. Citrate transporter, and Enolase-like, N-terminal
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1781_Mixed,_incl._Citrate_transporter,_and_Enolase-like,_N-terminal


id: CL:1798
description: Xylose metabolism, and Galactose mutarotase-like
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1798_Xylose_metabolism,_and_Galactose_mutarotase-like


id: CL:1814
description: Mixed, incl. DNA binding HTH domain, AraC-type, and Pentose and glucuronate interconversions
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1814_Mixed,_incl._DNA_binding_HTH_domain,_AraC-type,_and_Pentose_and_glucuronate_interconversions


id: CL:1816
description: Mixed, incl. Transcription regulator HTH-like, and MFS/sugar transport protein
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1816_Mixed,_incl._Transcription_regulator_HTH-like,_and_MFS/sugar_transport_protein


id: CL:1840
description: Pentose and glucuronate interconversions, and Sugar/inositol transporter
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1840_Pentose_and_glucuronate_interconversions,_and_Sugar/inositol_transporter


id: CL:1855
description: Mixed, incl. Active transmembrane transporter activity, and Lipoteichoic acid metabolic process
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1855_Mixed,_incl._Active_transmembrane_transporter_activity,_and_Lipoteichoic_acid_metabolic_process


id: CL:1856
description: Mixed, incl. Mtb iron assimilation by chelation, and Lipoteichoic acid metabolic process
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1856_Mixed,_incl._Mtb_iron_assimilation_by_chelation,_and_Lipoteichoic_acid_metabolic_process


id: CL:1857
description: Mixed, incl. Mtb iron assimilation by chelation, and Peptidase M16, C-terminal
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1857_Mixed,_incl._Mtb_iron_assimilation_by_chelation,_and_Peptidase_M16,_C-terminal


id: CL:1858
description: Mixed, incl. Peptidase M16, C-terminal, and Short-chain carboxylesterase activity
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1858_Mixed,_incl._Peptidase_M16,_C-terminal,_and_Short-chain_carboxylesterase_activity


id: CL:1860
description: Peptidase M16, C-terminal, and Alpha/beta hydrolase fold
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1860_Peptidase_M16,_C-terminal,_and_Alpha/beta_hydrolase_fold


id: CL:1881
description: Mtb iron assimilation by chelation, and Beta-lactamase-related
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1881_Mtb_iron_assimilation_by_chelation,_and_Beta-lactamase-related


id: CL:1891
description: Lipoteichoic acid metabolic process, and Alanine metabolic process
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1891_Lipoteichoic_acid_metabolic_process,_and_Alanine_metabolic_process


id: CL:1893
description: Lipoteichoic acid metabolic process
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1893_Lipoteichoic_acid_metabolic_process


id: CL:1918
description: Mixed, incl. Phosphoprotein phosphatase activity, and Rhodanese-like domain
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1918_Mixed,_incl._Phosphoprotein_phosphatase_activity,_and_Rhodanese-like_domain


id: CL:1921
description: Dephosphorylation, and Rhodanese-like domain
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1921_Dephosphorylation,_and_Rhodanese-like_domain


id: CL:1947
description: Mixed, incl. Tetrapyrrole biosynthetic process, and YibE/F-like
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1947_Mixed,_incl._Tetrapyrrole_biosynthetic_process,_and_YibE/F-like


id: CL:1965
description: Mixed, incl. Ferrochelatase, and Monocarboxylic acid transmembrane transporter activity
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1965_Mixed,_incl._Ferrochelatase,_and_Monocarboxylic_acid_transmembrane_transporter_activity


id: CL:197
description: Initiation factor, and Translational readthrough
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:197_Initiation_factor,_and_Translational_readthrough


id: CL:1980
description: Mixed, incl. Exopeptidase activity, and PTR2 family proton/oligopeptide symporter, conserved site
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1980_Mixed,_incl._Exopeptidase_activity,_and_PTR2_family_proton/oligopeptide_symporter,_conserved_site


id: CL:1981
description: Mixed, incl. Aminopeptidase, and Cell tip
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1981_Mixed,_incl._Aminopeptidase,_and_Cell_tip


id: CL:1983
description: Mixed, incl. Aminopeptidase, and Cell tip
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1983_Mixed,_incl._Aminopeptidase,_and_Cell_tip


id: CL:1986
description: Aminopeptidase, and Peptidase family M20/M25/M40
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:1986_Aminopeptidase,_and_Peptidase_family_M20/M25/M40


id: CL:2015
description: Mixed, incl. Thiol protease, and PIN-like domain superfamily
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2015_Mixed,_incl._Thiol_protease,_and_PIN-like_domain_superfamily


id: CL:2024
description: Mixed, incl. Aminoacyl-tRNA editing domain, and UbiC transcription regulator-associated
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2024_Mixed,_incl._Aminoacyl-tRNA_editing_domain,_and_UbiC_transcription_regulator-associated


id: CL:2040
description: Mixed, incl. Phosphorelay signal transduction system, and Phosphate ion transport
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2040_Mixed,_incl._Phosphorelay_signal_transduction_system,_and_Phosphate_ion_transport


id: CL:2041
description: Mixed, incl. Phosphorelay signal transduction system, and Aldo/keto reductase family
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2041_Mixed,_incl._Phosphorelay_signal_transduction_system,_and_Aldo/keto_reductase_family


id: CL:2042
description: Phosphorelay signal transduction system, and Aldo/keto reductase family
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2042_Phosphorelay_signal_transduction_system,_and_Aldo/keto_reductase_family


id: CL:2044
description: Phosphorelay signal transduction system, and tRNA 3-trailer cleavage
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2044_Phosphorelay_signal_transduction_system,_and_tRNA_3-trailer_cleavage


id: CL:2046
description: Two-component regulatory system, and His Kinase A (phosphoacceptor) domain
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2046_Two-component_regulatory_system,_and_His_Kinase_A_(phosphoacceptor)_domain


id: CL:2063
description: Mixed, incl. PAS domain, and tRNA 3-trailer cleavage
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2063_Mixed,_incl._PAS_domain,_and_tRNA_3-trailer_cleavage


id: CL:2080
description: MerR transcriptional regulator, and Aldo/keto reductase family
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2080_MerR_transcriptional_regulator,_and_Aldo/keto_reductase_family


id: CL:2089
description: Mixed, incl. PD-(D/E)XK nuclease superfamily, and Major Facilitator Superfamily
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2089_Mixed,_incl._PD-(D/E)XK_nuclease_superfamily,_and_Major_Facilitator_Superfamily


id: CL:2090
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2090_Mostly_uncharacterized,_incl._Haloacid_dehalogenase-like_hydrolase,_and_Phosphoric_diester_hydrolase_activity

description:
  Mostly uncharacterized, incl. Haloacid dehalogenase-like hydrolase, and Phosphoric diester hydrolase activity


id: CL:2091
description: Mixed, incl. Haloacid dehalogenase-like hydrolase, and 1,4-alpha-oligoglucan phosphorylase activity
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2091_Mixed,_incl._Haloacid_dehalogenase-like_hydrolase,_and_1,4-alpha-oligoglucan_phosphorylase_activity


id: CL:2102
description: Mixed, incl. Phosphoric diester hydrolase activity, and RelA/SpoT
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2102_Mixed,_incl._Phosphoric_diester_hydrolase_activity,_and_RelA/SpoT


id: CL:2112
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2112_Mixed,_incl._PD-(D/E)XK_nuclease_superfamily,_and_Periplasmic_binding_protein/LacI_sugar_binding_domain

description:
  Mixed, incl. PD-(D/E)XK nuclease superfamily, and Periplasmic binding protein/LacI sugar binding domain


id: CL:2145
description: Mixed, incl. Terpenoid backbone biosynthesis, and Quinone metabolic process
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2145_Mixed,_incl._Terpenoid_backbone_biosynthesis,_and_Quinone_metabolic_process


id: CL:2147
description: Mixed, incl. Demethylmenaquinone methyltransferase activity, and Cytochrome complex
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2147_Mixed,_incl._Demethylmenaquinone_methyltransferase_activity,_and_Cytochrome_complex


id: CL:2149
description: Cytochrome complex, and ABC transporter transmembrane region
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2149_Cytochrome_complex,_and_ABC_transporter_transmembrane_region


id: CL:217
description: Large ribosomal subunit, and AMP salvage
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:217_Large_ribosomal_subunit,_and_AMP_salvage


id: CL:2171
description: Mixed, incl. Terpenoid backbone biosynthesis, and tRNA 3-trailer cleavage
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2171_Mixed,_incl._Terpenoid_backbone_biosynthesis,_and_tRNA_3-trailer_cleavage


id: CL:2194
description: Mixed, incl. Metal ion transport, and Peptidase family C69
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2194_Mixed,_incl._Metal_ion_transport,_and_Peptidase_family_C69


id: CL:2195
description: Mixed, incl. Antiporter activity, and Potassium ion transport
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2195_Mixed,_incl._Antiporter_activity,_and_Potassium_ion_transport


id: CL:2197
description: Mixed, incl. Cation/H+ exchanger, and Potassium ion transport
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2197_Mixed,_incl._Cation/H+_exchanger,_and_Potassium_ion_transport


id: CL:2199
description: Mixed, incl. Regulator of K+ conductance, N-terminal, and Cation transporter/ATPase, N-terminus
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2199_Mixed,_incl._Regulator_of_K+_conductance,_N-terminal,_and_Cation_transporter/ATPase,_N-terminus


id: CL:2221
description: Mixed, incl. Thioredoxin, and Na+/H+ antiporter family
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2221_Mixed,_incl._Thioredoxin,_and_Na+/H+_antiporter_family


id: CL:2241
description: Mixed, incl. Parallel beta-helix repeats, and Positive regulation of RNA metabolic process
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2241_Mixed,_incl._Parallel_beta-helix_repeats,_and_Positive_regulation_of_RNA_metabolic_process


id: CL:2243
description: Mixed, incl. Positive regulation of RNA metabolic process, and Parallel beta-helix repeats
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2243_Mixed,_incl._Positive_regulation_of_RNA_metabolic_process,_and_Parallel_beta-helix_repeats


id: CL:2260
description: Mixed, incl. PspC domain, and Protein serine/threonine kinase activity
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2260_Mixed,_incl._PspC_domain,_and_Protein_serine/threonine_kinase_activity


id: CL:2270
description: Mixed, incl. NADP-dependent oxidoreductase domain superfamily, and Polyol catabolic process
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2270_Mixed,_incl._NADP-dependent_oxidoreductase_domain_superfamily,_and_Polyol_catabolic_process


id: CL:2272
description: Mixed, incl. Polyol catabolic process, and Major facilitator, sugar transporter-like
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2272_Mixed,_incl._Polyol_catabolic_process,_and_Major_facilitator,_sugar_transporter-like


id: CL:2274
description: Polyol catabolic process, and Sugar/inositol transporter
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2274_Polyol_catabolic_process,_and_Sugar/inositol_transporter


id: CL:2296
description: Mixed, incl. Aspartate 4-decarboxylase, and Xylose isomerase-like, TIM barrel domain
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2296_Mixed,_incl._Aspartate_4-decarboxylase,_and_Xylose_isomerase-like,_TIM_barrel_domain


id: CL:230
description: Mixed, incl. Allosteric enzyme, and Trigger factor/SurA domain superfamily
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:230_Mixed,_incl._Allosteric_enzyme,_and_Trigger_factor/SurA_domain_superfamily


id: CL:2315
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2315_Mixed,_incl._NADP-dependent_oxidoreductase_domain_superfamily,_and_Small_Multidrug_Resistance_protein

description:
  Mixed, incl. NADP-dependent oxidoreductase domain superfamily, and Small Multidrug Resistance protein


id: CL:2317
description: Mixed, incl. Aldo/keto reductase family
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2317_Mixed,_incl._Aldo/keto_reductase_family


id: CL:2331
description: Unsaturated fatty acid metabolic process, and Vicinal oxygen chelate (VOC) domain
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2331_Unsaturated_fatty_acid_metabolic_process,_and_Vicinal_oxygen_chelate_(VOC)_domain


id: CL:2349
description: Mixed, incl. ABC transporters, and Arginine and proline metabolism
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2349_Mixed,_incl._ABC_transporters,_and_Arginine_and_proline_metabolism


id: CL:2350
description: Mixed, incl. ABC-type polyamine transporter activity, and Arginine and proline metabolism
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2350_Mixed,_incl._ABC-type_polyamine_transporter_activity,_and_Arginine_and_proline_metabolism


id: CL:2351
description: Mixed, incl. ABC-type polyamine transporter activity, and Arginine and proline metabolism
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2351_Mixed,_incl._ABC-type_polyamine_transporter_activity,_and_Arginine_and_proline_metabolism


id: CL:2352
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2352_Mixed,_incl._ABC-type_polyamine_transporter_activity,_and_Bacterial_extracellular_solute-binding_protein

description:
  Mixed, incl. ABC-type polyamine transporter activity, and Bacterial extracellular solute-binding protein


id: CL:2353
description: Mixed, incl. SNARE associated Golgi protein, and ABC-type polyamine transporter activity
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2353_Mixed,_incl._SNARE_associated_Golgi_protein,_and_ABC-type_polyamine_transporter_activity


id: CL:2356
description: Mixed, incl. ABC-type polyamine transporter activity, and Nucleotide-diphospho-sugar transferases
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2356_Mixed,_incl._ABC-type_polyamine_transporter_activity,_and_Nucleotide-diphospho-sugar_transferases


id: CL:2358
description: Mixed, incl. Cysteine-rich domain, and Carotenoid biosynthesis
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2358_Mixed,_incl._Cysteine-rich_domain,_and_Carotenoid_biosynthesis


id: CL:2384
description: Mixed, incl. Polyamine transport, and Alcohol binding
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2384_Mixed,_incl._Polyamine_transport,_and_Alcohol_binding


id: CL:2400
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2400_Mixed,_incl._Glycine/sarcosine/betaine_reductase_complex,_protein_B,_subunit_alpha/_beta,_and_Selenium

description:
  Mixed, incl. Glycine/sarcosine/betaine reductase complex, protein B, subunit alpha/ beta, and Selenium


id: CL:2404
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2404_Mixed,_incl._Glycine/sarcosine/betaine_reductase_complex,_protein_B,_subunit_alpha/_beta,_and_Oxidoreductase_activity,_acting_on_X-H_and_Y-H_to_form_an_X-Y_bond

description:
  Mixed, incl. Glycine/sarcosine/betaine reductase complex, protein B, subunit alpha/ beta, and Oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond


id: CL:2420
description: Selenium, and tRNA thio-modification
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2420_Selenium,_and_tRNA_thio-modification


id: CL:2434
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2434_Mixed,_incl._Oxidoreductase_activity,_acting_on_a_sulfur_group_of_donors,_disulfide_as_acceptor,_and_Thioredoxin

description:
  Mixed, incl. Oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor, and Thioredoxin


id: CL:2436
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2436_Mixed,_incl._Oxidoreductase_activity,_acting_on_a_sulfur_group_of_donors,_disulfide_as_acceptor,_and_Thioredoxin

description:
  Mixed, incl. Oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor, and Thioredoxin


id: CL:2455
description: Mixed, incl. ABC transporters, and Arginine biosynthesis
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2455_Mixed,_incl._ABC_transporters,_and_Arginine_biosynthesis


id: CL:2456
description: Mixed, incl. ABC transporters, and Arginine biosynthesis
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2456_Mixed,_incl._ABC_transporters,_and_Arginine_biosynthesis


id: CL:2457
description: Mixed, incl. Amino acid transport, and MacB, ATP-binding domain
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2457_Mixed,_incl._Amino_acid_transport,_and_MacB,_ATP-binding_domain


id: CL:2458
description: Mixed, incl. Bacterial periplasmic substrate-binding proteins, and MacB, ATP-binding domain
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2458_Mixed,_incl._Bacterial_periplasmic_substrate-binding_proteins,_and_MacB,_ATP-binding_domain


id: CL:2460
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2460_Mixed,_incl._Bacterial_periplasmic_substrate-binding_proteins,_and_ABC-type_amino_acid_transport_system,_ATPase_component,_HisP-type

description:
  Mixed, incl. Bacterial periplasmic substrate-binding proteins, and ABC-type amino acid transport system, ATPase component, HisP-type


id: CL:2462
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2462_Bacterial_periplasmic_substrate-binding_proteins,_and_ABC-type_amino_acid_transport_system,_ATPase_component,_HisP-type

description:
  Bacterial periplasmic substrate-binding proteins, and ABC-type amino acid transport system, ATPase component, HisP-type


id: CL:247
description: Mixed, incl. RF-1 domain, and KOW (Kyprides, Ouzounis, Woese) motif.
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:247_Mixed,_incl._RF-1_domain,_and_KOW_(Kyprides,_Ouzounis,_Woese)_motif.


id: CL:2486
description: MacB, ATP-binding domain, and ABC3 transporter permease protein domain
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2486_MacB,_ATP-binding_domain,_and_ABC3_transporter_permease_protein_domain


id: CL:2503
description: NlpA lipoprotein, and Methionine transport
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2503_NlpA_lipoprotein,_and_Methionine_transport


id: CL:2521
description: Mixed, incl. Cation efflux family, and ABC transporter, BtuC-like
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2521_Mixed,_incl._Cation_efflux_family,_and_ABC_transporter,_BtuC-like


id: CL:2524
description: Mixed, incl. ABC transporter, BtuC-like, and Ferrous iron transporter FeoA domain
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2524_Mixed,_incl._ABC_transporter,_BtuC-like,_and_Ferrous_iron_transporter_FeoA_domain


id: CL:2546
description: Mixed, incl. Acid phosphatase homologues, and EamA-like transporter family
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2546_Mixed,_incl._Acid_phosphatase_homologues,_and_EamA-like_transporter_family


id: CL:2561
description: Mixed, incl. Prosthetic group metabolic process, and Iron-sulfur cluster assembly
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2561_Mixed,_incl._Prosthetic_group_metabolic_process,_and_Iron-sulfur_cluster_assembly


id: CL:2562
description: Mixed, incl. Iron-sulfur cluster assembly, and Iron ion homeostasis
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2562_Mixed,_incl._Iron-sulfur_cluster_assembly,_and_Iron_ion_homeostasis


id: CL:2564
description: Mixed, incl. Iron-sulfur cluster assembly, and rRNA processing
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2564_Mixed,_incl._Iron-sulfur_cluster_assembly,_and_rRNA_processing


id: CL:2565
description: Mixed, incl. Iron-sulfur cluster assembly, and Cysteine desulfurase activity
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2565_Mixed,_incl._Iron-sulfur_cluster_assembly,_and_Cysteine_desulfurase_activity


id: CL:2569
description: SUF system FeS cluster assembly, SufBD, and Cysteine desulfurase activity
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2569_SUF_system_FeS_cluster_assembly,_SufBD,_and_Cysteine_desulfurase_activity


id: CL:2587
description: Mixed, incl. Isoprene biosynthesis, and Metal-dependent hydrolase
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2587_Mixed,_incl._Isoprene_biosynthesis,_and_Metal-dependent_hydrolase


id: CL:2599
description: Mixed, incl. Ferritin-like, and ATP-cone domain
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2599_Mixed,_incl._Ferritin-like,_and_ATP-cone_domain


id: CL:2615
description: Mixed, incl. Prosthetic group metabolic process, and Nitrogen metabolism
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2615_Mixed,_incl._Prosthetic_group_metabolic_process,_and_Nitrogen_metabolism


id: CL:2616
description: Mixed, incl. Prosthetic group metabolic process, and Nitrogen metabolism
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2616_Mixed,_incl._Prosthetic_group_metabolic_process,_and_Nitrogen_metabolism


id: CL:2617
description: Prosthetic group metabolic process, and Nitrogen metabolism
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2617_Prosthetic_group_metabolic_process,_and_Nitrogen_metabolism


id: CL:2620
description: Prosthetic group metabolic process
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2620_Prosthetic_group_metabolic_process


id: CL:2646
description: Mixed, incl. GAF domain, and Isoprenoid synthase domain superfamily
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2646_Mixed,_incl._GAF_domain,_and_Isoprenoid_synthase_domain_superfamily


id: CL:2657
description: Mixed, incl. ABC transporter, BtuC-like, and Iron ion transport
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2657_Mixed,_incl._ABC_transporter,_BtuC-like,_and_Iron_ion_transport


id: CL:2675
description: Mixed, incl. Histidine metabolism, and Polymerase/histidinol phosphatase-like
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2675_Mixed,_incl._Histidine_metabolism,_and_Polymerase/histidinol_phosphatase-like


id: CL:2677
description: Mixed, incl. Methyltransferase domain, and tRNA methylation
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2677_Mixed,_incl._Methyltransferase_domain,_and_tRNA_methylation


id: CL:2695
description: Mixed, incl. Transmembrane, and Signal
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2695_Mixed,_incl._Transmembrane,_and_Signal


id: CL:2696
description: Mixed, incl. Signal, and Polysaccharide biosynthetic process
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2696_Mixed,_incl._Signal,_and_Polysaccharide_biosynthetic_process


id: CL:2697
description: Mixed, incl. Secreted, and Signal
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2697_Mixed,_incl._Secreted,_and_Signal


id: CL:2698
description: Mixed, incl. Secreted, and Signal
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2698_Mixed,_incl._Secreted,_and_Signal


id: CL:2699
description: Mixed, incl. Secreted, and Signal
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2699_Mixed,_incl._Secreted,_and_Signal


id: CL:2700
description: Mixed, incl. Secreted, and Signal
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2700_Mixed,_incl._Secreted,_and_Signal


id: CL:2701
description: Mixed, incl. Secreted, and Signal
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2701_Mixed,_incl._Secreted,_and_Signal


id: CL:2703
description: Mixed, incl. Signal, and DDE transposase sub-family
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2703_Mixed,_incl._Signal,_and_DDE_transposase_sub-family


id: CL:2705
description: Mixed, incl. Signal, and DDE transposase sub-family
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2705_Mixed,_incl._Signal,_and_DDE_transposase_sub-family


id: CL:2707
description: Mixed, incl. DDE transposase sub-family, and Mub B2-like domain
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2707_Mixed,_incl._DDE_transposase_sub-family,_and_Mub_B2-like_domain


id: CL:2709
description: Mixed, incl. Mub B2-like domain, and KxYKxGKxW signal peptide
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2709_Mixed,_incl._Mub_B2-like_domain,_and_KxYKxGKxW_signal_peptide


id: CL:2710
description: Mixed, incl. Mub B2-like domain, and Antibiotic metabolic process
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2710_Mixed,_incl._Mub_B2-like_domain,_and_Antibiotic_metabolic_process


id: CL:2712
description: YSIRK type signal peptide, and KxYKxGKxW signal peptide
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2712_YSIRK_type_signal_peptide,_and_KxYKxGKxW_signal_peptide


id: CL:2713
description: Mixed, incl. Sulphur transport, and Collagen binding
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2713_Mixed,_incl._Sulphur_transport,_and_Collagen_binding


id: CL:2724
description: Mixed, incl. Sensor histidine kinase NatK, C-terminal domain, and MucBP domain
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2724_Mixed,_incl._Sensor_histidine_kinase_NatK,_C-terminal_domain,_and_MucBP_domain


id: CL:2744
description: Mixed, incl. N-acetylmuramoyl-L-alanine amidase activity, and Monooxygenase
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2744_Mixed,_incl._N-acetylmuramoyl-L-alanine_amidase_activity,_and_Monooxygenase


id: CL:2761
description: DDE transposase sub-family, and Cytoskeletal motor activity
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2761_DDE_transposase_sub-family,_and_Cytoskeletal_motor_activity


id: CL:2763
description: Cytoskeletal motor activity, and Monobactam biosynthesis
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2763_Cytoskeletal_motor_activity,_and_Monobactam_biosynthesis


id: CL:2807
description: Mixed, incl. Secreted, and DNA-templated transcription, initiation
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2807_Mixed,_incl._Secreted,_and_DNA-templated_transcription,_initiation


id: CL:2808
description: Mixed, incl. Domain of unknown function DUF1542, and Mucin binding domain
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2808_Mixed,_incl._Domain_of_unknown_function_DUF1542,_and_Mucin_binding_domain


id: CL:2810
description: Mixed, incl. Beta-lactamase-related, and Domain of unknown function DUF1542
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2810_Mixed,_incl._Beta-lactamase-related,_and_Domain_of_unknown_function_DUF1542


id: CL:2820
description: Mixed, incl. Mucin binding domain, and Linear amide C-N hydrolases, choloylglycine hydrolase family
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2820_Mixed,_incl._Mucin_binding_domain,_and_Linear_amide_C-N_hydrolases,_choloylglycine_hydrolase_family


id: CL:2833
description: Protein of unknown function DUF285, and Bacterial invasion of epithelial cells
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2833_Protein_of_unknown_function_DUF285,_and_Bacterial_invasion_of_epithelial_cells


id: CL:2850
description: Mixed, incl. Sortase family, and Transposase, IS30, conserved site
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2850_Mixed,_incl._Sortase_family,_and_Transposase,_IS30,_conserved_site


id: CL:2864
description: Mixed, incl. Cellular carbohydrate biosynthetic process, and Nucleoplasm
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2864_Mixed,_incl._Cellular_carbohydrate_biosynthetic_process,_and_Nucleoplasm


id: CL:2866
description: Mixed, incl. LytTR DNA-binding domain, and Alpha/beta hydrolase of unknown function (DUF915)
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2866_Mixed,_incl._LytTR_DNA-binding_domain,_and_Alpha/beta_hydrolase_of_unknown_function_(DUF915)


id: CL:2880
description: Mixed, incl. Nucleoplasm, and Protein of unknown function (DUF2992)
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2880_Mixed,_incl._Nucleoplasm,_and_Protein_of_unknown_function_(DUF2992)


id: CL:2898
description: Mostly uncharacterized, incl. His-Me finger superfamily, and DnaD-like domain superfamily
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2898_Mostly_uncharacterized,_incl._His-Me_finger_superfamily,_and_DnaD-like_domain_superfamily


id: CL:2902
description: Mixed, incl. DnaD-like domain superfamily, and N-6 DNA Methylase
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2902_Mixed,_incl._DnaD-like_domain_superfamily,_and_N-6_DNA_Methylase


id: CL:2929
description: Mixed, incl. Zinc-ribbon domain, and NrdI Flavodoxin like
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2929_Mixed,_incl._Zinc-ribbon_domain,_and_NrdI_Flavodoxin_like


id: CL:2949
description: Mixed, incl. Polysaccharide biosynthetic process, and Glycosyl transferases group 1
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2949_Mixed,_incl._Polysaccharide_biosynthetic_process,_and_Glycosyl_transferases_group_1


id: CL:2951
description: Mixed, incl. Polysaccharide biosynthetic process, and Glycosyl transferases group 1
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2951_Mixed,_incl._Polysaccharide_biosynthetic_process,_and_Glycosyl_transferases_group_1


id: CL:2952
description: Mixed, incl. Polysaccharide biosynthetic process, and Glycosyl transferases group 1
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2952_Mixed,_incl._Polysaccharide_biosynthetic_process,_and_Glycosyl_transferases_group_1


id: CL:2953
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2953_Mixed,_incl._Polysaccharide_biosynthetic_process,_and_Glycosyltransferase_subfamily_4-like,_N-terminal_domain

description:
  Mixed, incl. Polysaccharide biosynthetic process, and Glycosyltransferase subfamily 4-like, N-terminal domain


id: CL:2954
description: Mixed, incl. Polysaccharide biosynthetic process, and Polyketide sugar unit biosynthesis
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2954_Mixed,_incl._Polysaccharide_biosynthetic_process,_and_Polyketide_sugar_unit_biosynthesis


id: CL:2957
description: Polyketide sugar unit biosynthesis, and NAD(P)-binding Rossmann-like domain
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2957_Polyketide_sugar_unit_biosynthesis,_and_NAD(P)-binding_Rossmann-like_domain


id: CL:2977
description: Lipopolysaccharide biosynthetic process, and Cell aggregation
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2977_Lipopolysaccharide_biosynthetic_process,_and_Cell_aggregation


id: CL:2992
description: Glycosyl transferase, family 1, and Lysyltransferase activity
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:2992_Glycosyl_transferase,_family_1,_and_Lysyltransferase_activity


id: CL:3005
description: Lipopolysaccharide biosynthesis, and Sortase domain
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3005_Lipopolysaccharide_biosynthesis,_and_Sortase_domain


id: CL:301
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:301_aminoacyl-tRNA_ligase_activity,_and_Topoisomerases,_DnaG-type_primases,_OLD_family_nucleases_and_RecR_proteins

description:
  aminoacyl-tRNA ligase activity, and Topoisomerases, DnaG-type primases, OLD family nucleases and RecR proteins


id: CL:3017
description: Regulation of growth rate, and Cell aggregation
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3017_Regulation_of_growth_rate,_and_Cell_aggregation


id: CL:3041
description: Mixed, incl. Hexose transmembrane transporter activity, and Protein of unknown function DUF421
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3041_Mixed,_incl._Hexose_transmembrane_transporter_activity,_and_Protein_of_unknown_function_DUF421


id: CL:3043
description: Mixed, incl. Type I phosphodiesterase / nucleotide pyrophosphatase, and Peptidase, metallopeptidase
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3043_Mixed,_incl._Type_I_phosphodiesterase_/_nucleotide_pyrophosphatase,_and_Peptidase,_metallopeptidase


id: CL:3060
description: Protein of unknown function DUF421, and Protein of unknown function DUF3290
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3060_Protein_of_unknown_function_DUF421,_and_Protein_of_unknown_function_DUF3290


id: CL:3076
description: Mixed, incl. Transmembrane, and DNA binding
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3076_Mixed,_incl._Transmembrane,_and_DNA_binding


id: CL:3077
description: Mixed, incl. Transmembrane, and Nucleic acid binding
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3077_Mixed,_incl._Transmembrane,_and_Nucleic_acid_binding


id: CL:3078
description: Mixed, incl. Transmembrane, and DNA-binding HTH domain, TetR-type
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3078_Mixed,_incl._Transmembrane,_and_DNA-binding_HTH_domain,_TetR-type


id: CL:3079
description: Mixed, incl. beta-Lactam resistance, and Transmembrane
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3079_Mixed,_incl._beta-Lactam_resistance,_and_Transmembrane


id: CL:3080
description: Mixed, incl. Transmembrane, and rRNA processing
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3080_Mixed,_incl._Transmembrane,_and_rRNA_processing


id: CL:3081
description: Mixed, incl. Transmembrane, and Endoribonuclease activity
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3081_Mixed,_incl._Transmembrane,_and_Endoribonuclease_activity


id: CL:3082
description: Mixed, incl. Transmembrane, and Helix-turn-helix XRE-family like proteins
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3082_Mixed,_incl._Transmembrane,_and_Helix-turn-helix_XRE-family_like_proteins


id: CL:3083
description: Mostly uncharacterized, incl. FAD binding, and Ppx/GppA phosphatase
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3083_Mostly_uncharacterized,_incl._FAD_binding,_and_Ppx/GppA_phosphatase


id: CL:3085
description: Mostly uncharacterized, incl. Ppx/GppA phosphatase, and Membrane organization
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3085_Mostly_uncharacterized,_incl._Ppx/GppA_phosphatase,_and_Membrane_organization


id: CL:3086
description: Mostly uncharacterized, incl. Ppx/GppA phosphatase, and Membrane organization
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3086_Mostly_uncharacterized,_incl._Ppx/GppA_phosphatase,_and_Membrane_organization


id: CL:3088
description: Mostly uncharacterized, incl. Membrane organization, and Ferric-uptake regulator
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3088_Mostly_uncharacterized,_incl._Membrane_organization,_and_Ferric-uptake_regulator


id: CL:3090
description: Mostly uncharacterized, incl. Ferric-uptake regulator, and dUTP diphosphatase activity
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3090_Mostly_uncharacterized,_incl._Ferric-uptake_regulator,_and_dUTP_diphosphatase_activity


id: CL:3093
description: Mixed, incl. dUTP diphosphatase activity, and Bacterial membrane protein YfhO
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3093_Mixed,_incl._dUTP_diphosphatase_activity,_and_Bacterial_membrane_protein_YfhO


id: CL:3114
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3114_Mixed,_incl._Branched-chain_amino_acid_transport,_AzlD,_and_Phage_integrase,_N-terminal_SAM-like_domain

description:
  Mixed, incl. Branched-chain amino acid transport, AzlD, and Phage integrase, N-terminal SAM-like domain


id: CL:3132
description: Mixed, incl. Serine aminopeptidase, S33, and Helix-turn-helix XRE-family like proteins
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3132_Mixed,_incl._Serine_aminopeptidase,_S33,_and_Helix-turn-helix_XRE-family_like_proteins


id: CL:3145
description: Mixed, incl. FAD binding, and Ribonuclease H domain
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3145_Mixed,_incl._FAD_binding,_and_Ribonuclease_H_domain


id: CL:3155
description: Mostly uncharacterized, incl. beta-Lactam resistance, and Metal ion transport
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3155_Mostly_uncharacterized,_incl._beta-Lactam_resistance,_and_Metal_ion_transport


id: CL:3156
description: Mostly uncharacterized, incl. Ubiquinone, and PepSY domain
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3156_Mostly_uncharacterized,_incl._Ubiquinone,_and_PepSY_domain


id: CL:3157
description: Mostly uncharacterized, incl. PepSY domain, and SGNH hydrolase-type esterase domain
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3157_Mostly_uncharacterized,_incl._PepSY_domain,_and_SGNH_hydrolase-type_esterase_domain


id: CL:3160
description: Mixed, incl. SGNH hydrolase-type esterase domain, and Tetratricopeptide repeat
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3160_Mixed,_incl._SGNH_hydrolase-type_esterase_domain,_and_Tetratricopeptide_repeat


id: CL:3181
description: Mixed, incl. Base-excision repair, and Coiled coil
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3181_Mixed,_incl._Base-excision_repair,_and_Coiled_coil


id: CL:3195
description: Mostly uncharacterized, incl. CAAX-box protein maturation, and Iron ion transport
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3195_Mostly_uncharacterized,_incl._CAAX-box_protein_maturation,_and_Iron_ion_transport


id: CL:3198
description: Mixed, incl. CAAX-box protein maturation, and TrkA-C domain
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3198_Mixed,_incl._CAAX-box_protein_maturation,_and_TrkA-C_domain


id: CL:3222
description: Mixed, incl. Ribonuclease J, and MerR-type HTH domain
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3222_Mixed,_incl._Ribonuclease_J,_and_MerR-type_HTH_domain


id: CL:3235
description: Mixed, incl. Protein alkylation, and PUA-like superfamily
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3235_Mixed,_incl._Protein_alkylation,_and_PUA-like_superfamily


id: CL:325
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:325_Topoisomerases,_DnaG-type_primases,_OLD_family_nucleases_and_RecR_proteins,_and_Methionyl/Leucyl_tRNA_synthetase

description:
  Topoisomerases, DnaG-type primases, OLD family nucleases and RecR proteins, and Methionyl/Leucyl tRNA synthetase


id: CL:3251
description: Mixed, incl. DNA-binding HTH domain, TetR-type, and Helix-turn-helix XRE-family like proteins
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3251_Mixed,_incl._DNA-binding_HTH_domain,_TetR-type,_and_Helix-turn-helix_XRE-family_like_proteins


id: CL:3253
description: DNA-binding HTH domain, TetR-type, and Hydro-lyase activity
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3253_DNA-binding_HTH_domain,_TetR-type,_and_Hydro-lyase_activity


id: CL:3273
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3273_Mixed,_incl._Formyl_transferase-like,_C-terminal_domain_superfamily,_and_Helix-turn-helix_XRE-family_like_proteins

description:
  Mixed, incl. Formyl transferase-like, C-terminal domain superfamily, and Helix-turn-helix XRE-family like proteins


id: CL:3289
description: Mixed, incl. Enzyme binding, and Nicotinamide riboside transport
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3289_Mixed,_incl._Enzyme_binding,_and_Nicotinamide_riboside_transport


id: CL:3301
description: Mostly uncharacterized, incl. Lactate metabolic process, and Bacterial chemotaxis
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3301_Mostly_uncharacterized,_incl._Lactate_metabolic_process,_and_Bacterial_chemotaxis


id: CL:3302
description: Mostly uncharacterized, incl. Lactate metabolic process, and Bacterial chemotaxis
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3302_Mostly_uncharacterized,_incl._Lactate_metabolic_process,_and_Bacterial_chemotaxis


id: CL:3303
description: Mixed, incl. Lactate metabolic process, and Cationic antimicrobial peptide (CAMP) resistance
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3303_Mixed,_incl._Lactate_metabolic_process,_and_Cationic_antimicrobial_peptide_(CAMP)_resistance


id: CL:3304
description: Mixed, incl. Lactate metabolic process, and Antibiotic catabolic process
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3304_Mixed,_incl._Lactate_metabolic_process,_and_Antibiotic_catabolic_process


id: CL:3305
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3305_Mostly_uncharacterized,_incl._Antibiotic_catabolic_process,_and_Calcineurin-like_phosphoesterase_domain,_lpxH-type

description:
  Mostly uncharacterized, incl. Antibiotic catabolic process, and Calcineurin-like phosphoesterase domain, lpxH-type


id: CL:3307
description: Mixed, incl. Antibiotic catabolic process, and DHHA1 domain
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3307_Mixed,_incl._Antibiotic_catabolic_process,_and_DHHA1_domain


id: CL:3326
description: Mixed, incl. Lactate metabolic process, and Alpha/beta hydrolase of unknown function (DUF915)
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3326_Mixed,_incl._Lactate_metabolic_process,_and_Alpha/beta_hydrolase_of_unknown_function_(DUF915)


id: CL:3339
description: Mixed, incl. Sortase family, and L,D-transpeptidase catalytic domain
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3339_Mixed,_incl._Sortase_family,_and_L,D-transpeptidase_catalytic_domain


id: CL:335
description: Ribosomal small subunit biogenesis, and tRNA pseudouridine synthesis
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:335_Ribosomal_small_subunit_biogenesis,_and_tRNA_pseudouridine_synthesis


id: CL:3351
description: Mixed, incl. Membrane raft, and Peptidase, metallopeptidase
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3351_Mixed,_incl._Membrane_raft,_and_Peptidase,_metallopeptidase


id: CL:3367
description: Integrase, catalytic domain, and PUA-like superfamily
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3367_Integrase,_catalytic_domain,_and_PUA-like_superfamily


id: CL:3376
description: Mixed, incl. Peptidase family C69, and Steroid metabolic process
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3376_Mixed,_incl._Peptidase_family_C69,_and_Steroid_metabolic_process


id: CL:3387
description: Mostly uncharacterized, incl. LysR, substrate-binding, and Helix-turn-helix, HxlR type
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3387_Mostly_uncharacterized,_incl._LysR,_substrate-binding,_and_Helix-turn-helix,_HxlR_type


id: CL:3388
description: Mostly uncharacterized, incl. LysR, substrate-binding, and Flavodoxin
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3388_Mostly_uncharacterized,_incl._LysR,_substrate-binding,_and_Flavodoxin


id: CL:3389
description: Mixed, incl. LysR, substrate-binding, and Flavodoxin
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3389_Mixed,_incl._LysR,_substrate-binding,_and_Flavodoxin


id: CL:3391
description: Mixed, incl. Uracil-DNA glycosylase-like, and LysR, substrate-binding
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3391_Mixed,_incl._Uracil-DNA_glycosylase-like,_and_LysR,_substrate-binding


id: CL:3409
description: Mixed, incl. Flavodoxin, and AhpD-like
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3409_Mixed,_incl._Flavodoxin,_and_AhpD-like


id: CL:3425
description: Mixed, incl. Fluoride transmembrane transport, and NAD(P)-binding domain
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3425_Mixed,_incl._Fluoride_transmembrane_transport,_and_NAD(P)-binding_domain


id: CL:3426
description: Mixed, incl. Transcription regulator Rrf2, and Modified amino acid transport
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3426_Mixed,_incl._Transcription_regulator_Rrf2,_and_Modified_amino_acid_transport


id: CL:3437
description: Fluoride transmembrane transport, and NmrA-like family
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3437_Fluoride_transmembrane_transport,_and_NmrA-like_family


id: CL:3453
description: Mixed, incl. Helix-turn-helix, HxlR type, and RNA 2-O ribose methyltransferase substrate binding
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3453_Mixed,_incl._Helix-turn-helix,_HxlR_type,_and_RNA_2-O_ribose_methyltransferase_substrate_binding


id: CL:3454
description: Mixed, incl. ABC-transporter extension domain, and ABC transporter, lipoprotein release, LolD-like
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3454_Mixed,_incl._ABC-transporter_extension_domain,_and_ABC_transporter,_lipoprotein_release,_LolD-like


id: CL:3467
description: Helix-turn-helix, HxlR type, and RNA 2-O ribose methyltransferase substrate binding
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3467_Helix-turn-helix,_HxlR_type,_and_RNA_2-O_ribose_methyltransferase_substrate_binding


id: CL:3478
description: Mixed, incl. NADPH-dependent FMN reductase-like, and KxYKxGKxW signal peptide
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3478_Mixed,_incl._NADPH-dependent_FMN_reductase-like,_and_KxYKxGKxW_signal_peptide


id: CL:3480
description: Mixed, incl. NADPH-dependent FMN reductase-like, and TRAM domain
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3480_Mixed,_incl._NADPH-dependent_FMN_reductase-like,_and_TRAM_domain


id: CL:3481
description: Mixed, incl. Glutaminase, and Nitroreductase
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3481_Mixed,_incl._Glutaminase,_and_Nitroreductase


id: CL:3495
description: NADPH-dependent FMN reductase-like, and TRAM domain
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3495_NADPH-dependent_FMN_reductase-like,_and_TRAM_domain


id: CL:3517
description: Mixed, incl. Integrase, catalytic core, and Trp repressor/replication initiator
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3517_Mixed,_incl._Integrase,_catalytic_core,_and_Trp_repressor/replication_initiator


id: CL:3518
description: Mixed, incl. Integrase, catalytic core, and Trp repressor/replication initiator
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3518_Mixed,_incl._Integrase,_catalytic_core,_and_Trp_repressor/replication_initiator


id: CL:3519
description: Integrase, catalytic core, and Trp repressor/replication initiator
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3519_Integrase,_catalytic_core,_and_Trp_repressor/replication_initiator


id: CL:3520
description: Helix-turn-helix domain, and DDE transposase retroviral integrase sub-family
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3520_Helix-turn-helix_domain,_and_DDE_transposase_retroviral_integrase_sub-family


id: CL:3535
description: Mixed, incl. Ferritin-like, and Homeodomain-like domain
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3535_Mixed,_incl._Ferritin-like,_and_Homeodomain-like_domain


id: CL:3546
description: Mixed, incl. Cupredoxin, and Haloacid dehalogenase-like hydrolase
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3546_Mixed,_incl._Cupredoxin,_and_Haloacid_dehalogenase-like_hydrolase


id: CL:3557
description: Cadmium resistance transporter, and HTH ArsR-type DNA-binding domain
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3557_Cadmium_resistance_transporter,_and_HTH_ArsR-type_DNA-binding_domain


id: CL:3572
description: Mostly uncharacterized, incl. AAA C-terminal domain, and DNA restriction-modification system
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3572_Mostly_uncharacterized,_incl._AAA_C-terminal_domain,_and_DNA_restriction-modification_system


id: CL:3573
description: Mixed, incl. DNA restriction-modification system, and Toxin-antitoxin complex
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3573_Mixed,_incl._DNA_restriction-modification_system,_and_Toxin-antitoxin_complex


id: CL:3574
description: Mixed, incl. Toxin-antitoxin complex, and AAA C-terminal domain
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3574_Mixed,_incl._Toxin-antitoxin_complex,_and_AAA_C-terminal_domain


id: CL:3575
description: Mixed, incl. Toxin-antitoxin complex, and Restriction endonuclease type II-like
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3575_Mixed,_incl._Toxin-antitoxin_complex,_and_Restriction_endonuclease_type_II-like


id: CL:3586
description: Mixed, incl. AAA C-terminal domain, and Alpha/beta hydrolase fold
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3586_Mixed,_incl._AAA_C-terminal_domain,_and_Alpha/beta_hydrolase_fold


id: CL:3597
description: Mixed, incl. Restriction/modification DNA-methyltransferase, and NADPH-dependent FMN reductase-like
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3597_Mixed,_incl._Restriction/modification_DNA-methyltransferase,_and_NADPH-dependent_FMN_reductase-like


id: CL:3607
description: Mixed, incl. AAA C-terminal domain, and UspA
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3607_Mixed,_incl._AAA_C-terminal_domain,_and_UspA


id: CL:3619
description: Mixed, incl. Thiamine metabolic process, and ABC transporter, CbiO/EcfA subunit
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3619_Mixed,_incl._Thiamine_metabolic_process,_and_ABC_transporter,_CbiO/EcfA_subunit


id: CL:3621
description: Mixed, incl. ABC transporter, CbiO/EcfA subunit, and Cobalt transport protein
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3621_Mixed,_incl._ABC_transporter,_CbiO/EcfA_subunit,_and_Cobalt_transport_protein


id: CL:3622
description: Mixed, incl. ABC transporter, CbiO/EcfA subunit, and Cobalt transport protein
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3622_Mixed,_incl._ABC_transporter,_CbiO/EcfA_subunit,_and_Cobalt_transport_protein


id: CL:3624
description: Mixed, incl. ABC transporter, CbiO/EcfA subunit, and Cobalt transport protein
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3624_Mixed,_incl._ABC_transporter,_CbiO/EcfA_subunit,_and_Cobalt_transport_protein


id: CL:3625
description: ABC-type cobalt transport system, permease component, and Cobalt transport protein
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3625_ABC-type_cobalt_transport_system,_permease_component,_and_Cobalt_transport_protein


id: CL:3637
description: ABC transporter, CbiO/EcfA subunit, and ECF transporter, substrate-specific component
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3637_ABC_transporter,_CbiO/EcfA_subunit,_and_ECF_transporter,_substrate-specific_component


id: CL:364
description: Mixed, incl. Pseudouridine synthase, RluC/RluD, and SpoU rRNA Methylase family
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:364_Mixed,_incl._Pseudouridine_synthase,_RluC/RluD,_and_SpoU_rRNA_Methylase_family


id: CL:3657
description: Mixed, incl. Resolvase, HTH domain, and Transposase activity
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3657_Mixed,_incl._Resolvase,_HTH_domain,_and_Transposase_activity


id: CL:366
description: Pseudouridine synthase, RluC/RluD, and RNA helicase activity
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:366_Pseudouridine_synthase,_RluC/RluD,_and_RNA_helicase_activity


id: CL:3675
description: Thiamine metabolic process, and DedA family
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3675_Thiamine_metabolic_process,_and_DedA_family


id: CL:3693
description: DedA family, and FAD-binding, type PCMH, subdomain 2
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3693_DedA_family,_and_FAD-binding,_type_PCMH,_subdomain_2


id: CL:3703
description: Mixed, incl. Response to herbicide, and Acetyltransferase (GNAT) domain
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3703_Mixed,_incl._Response_to_herbicide,_and_Acetyltransferase_(GNAT)_domain


id: CL:3704
description: Response to herbicide, and Acetyltransferase (GNAT) domain
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3704_Response_to_herbicide,_and_Acetyltransferase_(GNAT)_domain


id: CL:3715
description: Mixed, incl. Peptidase C26, and Peptidase family M20/M25/M40
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3715_Mixed,_incl._Peptidase_C26,_and_Peptidase_family_M20/M25/M40


id: CL:3729
description: Mixed, incl. Response of Mtb to phagocytosis, and Heme biosynthetic process
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3729_Mixed,_incl._Response_of_Mtb_to_phagocytosis,_and_Heme_biosynthetic_process


id: CL:3730
description: Mixed, incl. Response of Mtb to phagocytosis, and Heme biosynthetic process
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3730_Mixed,_incl._Response_of_Mtb_to_phagocytosis,_and_Heme_biosynthetic_process


id: CL:3731
description: Mixed, incl. Response of Mtb to phagocytosis, and ThiF family
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3731_Mixed,_incl._Response_of_Mtb_to_phagocytosis,_and_ThiF_family


id: CL:3732
description: Drug resistance transporter EmrB-like, and Response of Mtb to phagocytosis
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3732_Drug_resistance_transporter_EmrB-like,_and_Response_of_Mtb_to_phagocytosis


id: CL:3734
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3734_Mixed,_incl._Drug_resistance_transporter_EmrB-like,_and_Helix_turn_helix_multiple_antibiotic_resistance_protein

description:
  Mixed, incl. Drug resistance transporter EmrB-like, and Helix_turn_helix multiple antibiotic resistance protein


id: CL:3753
description: Mixed, incl. ThiF family, and HTH ArsR-type DNA-binding domain
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3753_Mixed,_incl._ThiF_family,_and_HTH_ArsR-type_DNA-binding_domain


id: CL:3765
description: Mixed, incl. Heme biosynthetic process, and YqgF/RNase H-like domain
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3765_Mixed,_incl._Heme_biosynthetic_process,_and_YqgF/RNase_H-like_domain


id: CL:3766
description: Heme biosynthetic process, and Recombination-promoting nuclease RpnA
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3766_Heme_biosynthetic_process,_and_Recombination-promoting_nuclease_RpnA


id: CL:3779
description: Mixed, incl. YqgF/RNase H-like domain, and Nicotinate phosphoribosyltransferase family
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3779_Mixed,_incl._YqgF/RNase_H-like_domain,_and_Nicotinate_phosphoribosyltransferase_family


id: CL:3793
description: Mixed, incl. Major facilitator, sugar transporter-like, and MMPL family
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3793_Mixed,_incl._Major_facilitator,_sugar_transporter-like,_and_MMPL_family


id: CL:3795
description: Mixed, incl. MMPL family, and Bax inhibitor 1-related
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3795_Mixed,_incl._MMPL_family,_and_Bax_inhibitor_1-related


id: CL:3797
description: Mixed, incl. MMPL family, and Aminoacyl-tRNA editing domain
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3797_Mixed,_incl._MMPL_family,_and_Aminoacyl-tRNA_editing_domain


id: CL:3819
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3819_Mixed,_incl._Branched-chain_amino_acid_transport,_AzlD,_and_Branched-chain_amino_acid_transport,_permease

description:
  Mixed, incl. Branched-chain amino acid transport, AzlD, and Branched-chain amino acid transport, permease


id: CL:3835
description: Mixed, incl. DNA modification, and Amino acid permease
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3835_Mixed,_incl._DNA_modification,_and_Amino_acid_permease


id: CL:3836
description: Mixed, incl. DNA modification, and Amino acid permease
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3836_Mixed,_incl._DNA_modification,_and_Amino_acid_permease


id: CL:3838
description: Mixed, incl. Amino acid permease, and Transketolase, N-terminal
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3838_Mixed,_incl._Amino_acid_permease,_and_Transketolase,_N-terminal


id: CL:384
description: Chaperone, and ATP-dependent peptidase activity
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:384_Chaperone,_and_ATP-dependent_peptidase_activity


id: CL:3855
description: DNA restriction-modification system, and Coiled coil
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3855_DNA_restriction-modification_system,_and_Coiled_coil


id: CL:386
description: Chaperone, and ATP-dependent Clp protease proteolytic subunit
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:386_Chaperone,_and_ATP-dependent_Clp_protease_proteolytic_subunit


id: CL:3870
description: Mixed, incl. Mycolic acid cyclopropane synthase, and AI-2E family transporter
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3870_Mixed,_incl._Mycolic_acid_cyclopropane_synthase,_and_AI-2E_family_transporter


id: CL:3889
description: Mostly uncharacterized, incl. Catalytic activity, acting on DNA, and Lysozyme activity
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3889_Mostly_uncharacterized,_incl._Catalytic_activity,_acting_on_DNA,_and_Lysozyme_activity


id: CL:3890
description: Mixed, incl. DNA metabolic process, and Lysozyme activity
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3890_Mixed,_incl._DNA_metabolic_process,_and_Lysozyme_activity


id: CL:3891
description: Mostly uncharacterized, incl. Base excision repair, and DNA integration
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3891_Mostly_uncharacterized,_incl._Base_excision_repair,_and_DNA_integration


id: CL:3893
description: Mostly uncharacterized, incl. Lysozyme activity, and AAA domain
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3893_Mostly_uncharacterized,_incl._Lysozyme_activity,_and_AAA_domain


id: CL:3894
description: Mostly uncharacterized, incl. AAA domain, and Phage capsid
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3894_Mostly_uncharacterized,_incl._AAA_domain,_and_Phage_capsid


id: CL:3895
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3895_Mostly_uncharacterized,_incl._Phage_head-tail_joining_protein_,_and_Phosphoric_diester_hydrolase_activity

description:
  Mostly uncharacterized, incl. Phage head-tail joining protein , and Phosphoric diester hydrolase activity


id: CL:3898
description: Mixed, incl. Peptidase M23, and Sister chromatid cohesion
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3898_Mixed,_incl._Peptidase_M23,_and_Sister_chromatid_cohesion


id: CL:3911
description: Mixed, incl. Phage head-tail joining protein , and Phage gp6-like head-tail connector protein
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3911_Mixed,_incl._Phage_head-tail_joining_protein_,_and_Phage_gp6-like_head-tail_connector_protein


id: CL:3923
description: Mixed, incl. Phage capsid, and Toxin activity
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3923_Mixed,_incl._Phage_capsid,_and_Toxin_activity


id: CL:3935
description: Mixed, incl. Glycosyl hydrolases family 25, and Coiled coil
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3935_Mixed,_incl._Glycosyl_hydrolases_family_25,_and_Coiled_coil


id: CL:3957
description: Mixed, incl. Base excision repair, and Resolvase, N terminal domain
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3957_Mixed,_incl._Base_excision_repair,_and_Resolvase,_N_terminal_domain


id: CL:3960
description: Mostly uncharacterized, incl. Phage capsid, and HNH nucleases
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3960_Mostly_uncharacterized,_incl._Phage_capsid,_and_HNH_nucleases


id: CL:3963
description: Mixed, incl. Phage capsid, and Toxin activity
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3963_Mixed,_incl._Phage_capsid,_and_Toxin_activity


id: CL:3974
description: Mixed, incl. HNH nucleases, and Terminase large subunit-like
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3974_Mixed,_incl._HNH_nucleases,_and_Terminase_large_subunit-like


id: CL:3991
description: Mixed, incl. Double-strand break repair, and tRNA endonuclease-like domain superfamily
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:3991_Mixed,_incl._Double-strand_break_repair,_and_tRNA_endonuclease-like_domain_superfamily


id: CL:4008
description: Mixed, incl. DNA methylase, and Restriction endodeoxyribonuclease activity
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:4008_Mixed,_incl._DNA_methylase,_and_Restriction_endodeoxyribonuclease_activity


id: CL:4017
description: Mixed, incl. Pantothenate biosynthesis, and Resolvase, HTH domain
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:4017_Mixed,_incl._Pantothenate_biosynthesis,_and_Resolvase,_HTH_domain


id: CL:4018
description: Mixed, incl. Resolvase, HTH domain, and Acid phosphatase homologues
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:4018_Mixed,_incl._Resolvase,_HTH_domain,_and_Acid_phosphatase_homologues


id: CL:4029
description: Mixed, incl. Pantothenate biosynthesis, and Response to pH
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:4029_Mixed,_incl._Pantothenate_biosynthesis,_and_Response_to_pH


id: CL:4040
description: Mixed, incl. Chromosome organization, and Toxin-antitoxin complex
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:4040_Mixed,_incl._Chromosome_organization,_and_Toxin-antitoxin_complex


id: CL:4041
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:4041_Mixed,_incl._DNA_topoisomerase_type_I_(single_strand_cut,_ATP-independent)_activity,_and_Exodeoxyribonuclease_V_complex

description:
  Mixed, incl. DNA topoisomerase type I (single strand cut, ATP-independent) activity, and Exodeoxyribonuclease V complex


id: CL:4042
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:4042_Mixed,_incl._DNA_topoisomerase_type_I_(single_strand_cut,_ATP-independent)_activity,_and_Exodeoxyribonuclease_V_complex

description:
  Mixed, incl. DNA topoisomerase type I (single strand cut, ATP-independent) activity, and Exodeoxyribonuclease V complex


id: CL:4043
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:4043_Mixed,_incl._DNA_topoisomerase_type_I_(single_strand_cut,_ATP-independent)_activity,_and_Exodeoxyribonuclease_V_complex

description:
  Mixed, incl. DNA topoisomerase type I (single strand cut, ATP-independent) activity, and Exodeoxyribonuclease V complex


id: CL:4045
description: Mixed, incl. Exodeoxyribonuclease V complex, and Replication initiator A, N-terminal
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:4045_Mixed,_incl._Exodeoxyribonuclease_V_complex,_and_Replication_initiator_A,_N-terminal


id: CL:4047
description: Exodeoxyribonuclease V complex, and Replication initiator A, N-terminal
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:4047_Exodeoxyribonuclease_V_complex,_and_Replication_initiator_A,_N-terminal


id: CL:4073
description: DNA topoisomerase type I (single strand cut, ATP-independent) activity
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:4073_DNA_topoisomerase_type_I_(single_strand_cut,_ATP-independent)_activity


id: CL:4082
description: Mixed, incl. Membrane transport protein, and Drug resistance transporter EmrB-like
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:4082_Mixed,_incl._Membrane_transport_protein,_and_Drug_resistance_transporter_EmrB-like


id: CL:4092
description: Mixed, incl. DNA topoisomerase, type IA, and Mannosylation
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:4092_Mixed,_incl._DNA_topoisomerase,_type_IA,_and_Mannosylation


id: CL:4112
description: Mixed, incl. Toxin-antitoxin complex, and YefM-like superfamily
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:4112_Mixed,_incl._Toxin-antitoxin_complex,_and_YefM-like_superfamily


id: CL:4113
description: Mixed, incl. Toxin-antitoxin complex, and YefM-like superfamily
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:4113_Mixed,_incl._Toxin-antitoxin_complex,_and_YefM-like_superfamily


id: CL:4115
description: Mixed, incl. Toxin-antitoxin complex, and YefM-like superfamily
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:4115_Mixed,_incl._Toxin-antitoxin_complex,_and_YefM-like_superfamily


id: CL:4117
description: Mixed, incl. AAA domain, and YefM-like superfamily
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:4117_Mixed,_incl._AAA_domain,_and_YefM-like_superfamily


id: CL:4135
description: Mixed, incl. YefM-like superfamily, and RelB antitoxin/Antitoxin DinJ
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:4135_Mixed,_incl._YefM-like_superfamily,_and_RelB_antitoxin/Antitoxin_DinJ


id: CL:4146
description: Mixed, incl. mRNA interferase PemK-like, and Signal
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:4146_Mixed,_incl._mRNA_interferase_PemK-like,_and_Signal


id: CL:4160
description: Mixed, incl. C-methyltransferase activity, and Protein of unknown function (DUF2992)
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:4160_Mixed,_incl._C-methyltransferase_activity,_and_Protein_of_unknown_function_(DUF2992)


id: CL:4170
description: Mixed, incl. Tryptophan metabolism, and Zinc-ribbon domain
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:4170_Mixed,_incl._Tryptophan_metabolism,_and_Zinc-ribbon_domain


id: CL:4203
description: Mixed, incl. Cell death, and Signal
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:4203_Mixed,_incl._Cell_death,_and_Signal


id: CL:4204
description: Mixed, incl. Cell death, and LytTR DNA-binding domain
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:4204_Mixed,_incl._Cell_death,_and_LytTR_DNA-binding_domain


id: CL:4205
description: Mixed, incl. Amidase activity, and Sensor histidine kinase NatK, C-terminal domain
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:4205_Mixed,_incl._Amidase_activity,_and_Sensor_histidine_kinase_NatK,_C-terminal_domain


id: CL:4208
description: Mixed, incl. Zinc-ribbon domain, and Response to antibiotic
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:4208_Mixed,_incl._Zinc-ribbon_domain,_and_Response_to_antibiotic


id: CL:422
description: Mixed, incl. Exoribonuclease activity, and Serine aminopeptidase, S33
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:422_Mixed,_incl._Exoribonuclease_activity,_and_Serine_aminopeptidase,_S33


id: CL:4249
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:4249_Mostly_uncharacterized,_incl._Lambda_repressor-like,_DNA-binding_domain_superfamily,_and_Alkaline_shock_protein_Asp23

description:
  Mostly uncharacterized, incl. Lambda repressor-like, DNA-binding domain superfamily, and Alkaline shock protein Asp23


id: CL:4250
description: Mixed, incl. Lambda repressor-like, DNA-binding domain superfamily, and Beta-lactamase activity
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:4250_Mixed,_incl._Lambda_repressor-like,_DNA-binding_domain_superfamily,_and_Beta-lactamase_activity


id: CL:4252
description: Mixed, incl. Helix-turn-helix XRE-family like proteins
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:4252_Mixed,_incl._Helix-turn-helix_XRE-family_like_proteins


id: CL:4265
description: Mixed, incl. Beta-lactamase activity, and Signal
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:4265_Mixed,_incl._Beta-lactamase_activity,_and_Signal


id: CL:4275
description: Mixed, incl. Alkaline shock protein Asp23, and Integrase/recombinase, N-terminal
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:4275_Mixed,_incl._Alkaline_shock_protein_Asp23,_and_Integrase/recombinase,_N-terminal


id: CL:4296
description: Mixed, incl. Zinc-ribbon domain, and Peptidoglycan biosynthesis
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:4296_Mixed,_incl._Zinc-ribbon_domain,_and_Peptidoglycan_biosynthesis


id: CL:431
description: Mixed, incl. Homologous recombination, and DNA repair complex
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:431_Mixed,_incl._Homologous_recombination,_and_DNA_repair_complex


id: CL:4311
description: Mixed, incl. Helix-turn-helix domain, and Intracellular protein-containing complex
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:4311_Mixed,_incl._Helix-turn-helix_domain,_and_Intracellular_protein-containing_complex


id: CL:433
description: DNA replication, and DNA repair complex
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:433_DNA_replication,_and_DNA_repair_complex


id: CL:435
description: Mismatch repair, and DNA damage sensor activity
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:435_Mismatch_repair,_and_DNA_damage_sensor_activity


id: CL:436
description: DNA damage sensor activity, and 3-5 exonuclease activity
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:436_DNA_damage_sensor_activity,_and_3-5_exonuclease_activity


id: CL:439
description: Mismatch repair, and DNA-directed DNA polymerase
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:439_Mismatch_repair,_and_DNA-directed_DNA_polymerase


id: CL:463
description: DNA polymerase complex, and Exonuclease, RNase T/DNA polymerase III
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:463_DNA_polymerase_complex,_and_Exonuclease,_RNase_T/DNA_polymerase_III


id: CL:483
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:483_Mixed,_incl._Chromosomal_replication_initiator_protein_DnaA,_and_DNA_topoisomerase,_type_IIA-like_domain_superfamily

description:
  Mixed, incl. Chromosomal replication initiator protein DnaA, and DNA topoisomerase, type IIA-like domain superfamily


id: CL:501
description: Mixed, incl. Holliday junction helicase complex, and DHHA1 domain
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:501_Mixed,_incl._Holliday_junction_helicase_complex,_and_DHHA1_domain


id: CL:503
description: Mixed, incl. RNA capping, and Secondary metabolic process
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:503_Mixed,_incl._RNA_capping,_and_Secondary_metabolic_process


id: CL:526
description: Mixed, incl. ParB/Spo0J, HTH domain, and tRNA processing
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:526_Mixed,_incl._ParB/Spo0J,_HTH_domain,_and_tRNA_processing


id: CL:528
description: Mixed, incl. tRNA processing, and rRNA base methylation
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:528_Mixed,_incl._tRNA_processing,_and_rRNA_base_methylation


id: CL:544
description: ParB/Spo0J, HTH domain, and TGS-like
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:544_ParB/Spo0J,_HTH_domain,_and_TGS-like


id: CL:555
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:555_Mixed,_incl._glutaminyl-tRNA_synthase_(glutamine-hydrolyzing)_activity,_and_Diacylglycerol_kinase,_catalytic_domain

description:
  Mixed, incl. glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity, and Diacylglycerol kinase, catalytic domain


id: CL:558
description: glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:558_glutaminyl-tRNA_synthase_(glutamine-hydrolyzing)_activity


id: CL:573
description: Diacylglycerol kinase, catalytic domain, and TRAM domain
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:573_Diacylglycerol_kinase,_catalytic_domain,_and_TRAM_domain


id: CL:589
description: Mixed, incl. DNA catabolic process, and NusB family
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:589_Mixed,_incl._DNA_catabolic_process,_and_NusB_family


id: CL:593
description: DNA catabolic process, and Polyprenyl synthetase
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:593_DNA_catabolic_process,_and_Polyprenyl_synthetase


id: CL:613
description: Mixed, incl. glycyl-tRNA aminoacylation, and Ribosome biogenesis
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:613_Mixed,_incl._glycyl-tRNA_aminoacylation,_and_Ribosome_biogenesis


id: CL:615
description: Ribosome biogenesis, and Bacterial nucleoid
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:615_Ribosome_biogenesis,_and_Bacterial_nucleoid


id: CL:639
description: Mixed, incl. Nucleotide biosynthetic process, and Pyrimidine metabolism
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:639_Mixed,_incl._Nucleotide_biosynthetic_process,_and_Pyrimidine_metabolism


id: CL:640
description: Mixed, incl. Nucleotide biosynthetic process, and Riboflavin metabolism
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:640_Mixed,_incl._Nucleotide_biosynthetic_process,_and_Riboflavin_metabolism


id: CL:641
description: Ribonucleoside monophosphate metabolic process, and Purine metabolism
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:641_Ribonucleoside_monophosphate_metabolic_process,_and_Purine_metabolism


id: CL:642
description: Mixed, incl. Ribonucleoside monophosphate metabolic process, and Riboflavin metabolism
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:642_Mixed,_incl._Ribonucleoside_monophosphate_metabolic_process,_and_Riboflavin_metabolism


id: CL:643
description: Ribonucleoside monophosphate biosynthetic process, and Purine nucleosidase activity
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:643_Ribonucleoside_monophosphate_biosynthetic_process,_and_Purine_nucleosidase_activity


id: CL:645
description: Purine nucleoside monophosphate biosynthetic process, and Purine nucleosidase activity
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:645_Purine_nucleoside_monophosphate_biosynthetic_process,_and_Purine_nucleosidase_activity


id: CL:647
description: Purine nucleoside monophosphate biosynthetic process
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:647_Purine_nucleoside_monophosphate_biosynthetic_process


id: CL:672
description: GMP biosynthetic process, and GMP reductase complex
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:672_GMP_biosynthetic_process,_and_GMP_reductase_complex


id: CL:687
description: Purine salvage, and Purine nucleosidase activity
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:687_Purine_salvage,_and_Purine_nucleosidase_activity


id: CL:706
description: De novo UMP biosynthetic process, and Quinone binding
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:706_De_novo_UMP_biosynthetic_process,_and_Quinone_binding


id: CL:728
description: Quinone binding, and Glutamate synthase activity
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:728_Quinone_binding,_and_Glutamate_synthase_activity


id: CL:74
description: Mixed, incl. Translation, and Chaperone
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:74_Mixed,_incl._Translation,_and_Chaperone


id: CL:742
description: Mixed, incl. Riboflavin metabolic process, and GDP metabolic process
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:742_Mixed,_incl._Riboflavin_metabolic_process,_and_GDP_metabolic_process


id: CL:743
description: Mixed, incl. GDP metabolic process, and GTP diphosphokinase activity
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:743_Mixed,_incl._GDP_metabolic_process,_and_GTP_diphosphokinase_activity


id: CL:745
description: GDP metabolic process, and GTP diphosphokinase activity
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:745_GDP_metabolic_process,_and_GTP_diphosphokinase_activity


id: CL:75
description: Mixed, incl. Translation, and Chaperone
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:75_Mixed,_incl._Translation,_and_Chaperone


id: CL:76
description: Translation, and Protein transport
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:76_Translation,_and_Protein_transport


id: CL:77
description: Translation, and Protein transport
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:77_Translation,_and_Protein_transport


id: CL:78
description: Translation, and Protein transport
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:78_Translation,_and_Protein_transport


id: CL:783
description: Mixed, incl. Asp/Glu racemase, and Nucleotide metabolism
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:783_Mixed,_incl._Asp/Glu_racemase,_and_Nucleotide_metabolism


id: CL:79
description: Translation, and Protein transport
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:79_Translation,_and_Protein_transport


id: CL:792
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:792_Mixed,_incl._Cellular_modified_amino_acid_metabolic_process,_and_Deoxyribonucleoside_monophosphate_biosynthetic_process

description:
  Mixed, incl. Cellular modified amino acid metabolic process, and Deoxyribonucleoside monophosphate biosynthetic process


id: CL:793
description: Mixed, incl. Protein serine/threonine phosphatase activity, and Cobalt
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:793_Mixed,_incl._Protein_serine/threonine_phosphatase_activity,_and_Cobalt


id: CL:796
description: Mixed, incl. Cobalt, and NusB family
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:796_Mixed,_incl._Cobalt,_and_NusB_family


id: CL:80
description: Ribosome, and Regulation of translation
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:80_Ribosome,_and_Regulation_of_translation


id: CL:81
description: Ribosome, and Regulation of translation
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:81_Ribosome,_and_Regulation_of_translation


id: CL:818
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:818_Deoxyribonucleoside_monophosphate_biosynthetic_process,_and_Pteridine-containing_compound_metabolic_process

description:
  Deoxyribonucleoside monophosphate biosynthetic process, and Pteridine-containing compound metabolic process


id: CL:82
description: Ribosome, and Regulation of translation
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:82_Ribosome,_and_Regulation_of_translation


id: CL:820
description: Pteridine-containing compound metabolic process
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:820_Pteridine-containing_compound_metabolic_process


id: CL:832
description: Deoxyribonucleoside monophosphate biosynthetic process, and MafB19-like deaminase
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:832_Deoxyribonucleoside_monophosphate_biosynthetic_process,_and_MafB19-like_deaminase


id: CL:842
description: Mixed, incl. 5-phosphoribose 1-diphosphate metabolic process, and Ribokinase/fructokinase
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:842_Mixed,_incl._5-phosphoribose_1-diphosphate_metabolic_process,_and_Ribokinase/fructokinase


id: CL:844
description: Mixed, incl. 5-phosphoribose 1-diphosphate metabolic process, and Uridine phosphorylase activity
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:844_Mixed,_incl._5-phosphoribose_1-diphosphate_metabolic_process,_and_Uridine_phosphorylase_activity


id: CL:846
description: Deoxyribonucleotide catabolic process, and Tryptophan metabolic process
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:846_Deoxyribonucleotide_catabolic_process,_and_Tryptophan_metabolic_process


id: CL:85
description: Ribosome, and Regulation of translation
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:85_Ribosome,_and_Regulation_of_translation


id: CL:86
description: Ribosome, and Translation regulator activity
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:86_Ribosome,_and_Translation_regulator_activity


id: CL:872
description: Mixed, incl. Ribokinase/fructokinase, and Nucleoplasm
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:872_Mixed,_incl._Ribokinase/fructokinase,_and_Nucleoplasm


id: CL:88
description: Ribonucleoprotein, and Translation regulator activity
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:88_Ribonucleoprotein,_and_Translation_regulator_activity


id: CL:892
description: Mixed, incl. Cell division, and Regulation of developmental process
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:892_Mixed,_incl._Cell_division,_and_Regulation_of_developmental_process


id: CL:893
description: Mixed, incl. Cell division, and Regulation of developmental process
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:893_Mixed,_incl._Cell_division,_and_Regulation_of_developmental_process


id: CL:894
description: Mixed, incl. Cell division, and Regulation of developmental process
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:894_Mixed,_incl._Cell_division,_and_Regulation_of_developmental_process


id: CL:896
description: Cell division, and Regulation of cell shape
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:896_Cell_division,_and_Regulation_of_cell_shape


id: CL:897
description: Cell division, and Serine-type D-Ala-D-Ala carboxypeptidase activity
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:897_Cell_division,_and_Serine-type_D-Ala-D-Ala_carboxypeptidase_activity


id: CL:899
description: Peptidoglycan synthesis, and PASTA domain
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:899_Peptidoglycan_synthesis,_and_PASTA_domain


id: CL:902
description: Vancomycin resistance, and Mur ligase, C-terminal
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:902_Vancomycin_resistance,_and_Mur_ligase,_C-terminal


id: CL:91
description: Ribonucleoprotein, and Regulation of translation
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:91_Ribonucleoprotein,_and_Regulation_of_translation


id: CL:919
description: Amino sugar biosynthetic process, and Alpha-D-phosphohexomutase superfamily
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:919_Amino_sugar_biosynthetic_process,_and_Alpha-D-phosphohexomutase_superfamily


id: CL:92
description: Ribonucleoprotein, and Regulation of translation
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:92_Ribonucleoprotein,_and_Regulation_of_translation


id: CL:935
description: Mixed, incl. Reproduction, and DivIVA family
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:935_Mixed,_incl._Reproduction,_and_DivIVA_family


id: CL:947
description: Septum formation initiator, and rRNA base methylation
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:947_Septum_formation_initiator,_and_rRNA_base_methylation


id: CL:957
description: Mixed, incl. Actin, and Cell cycle protein
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:957_Mixed,_incl._Actin,_and_Cell_cycle_protein


id: CL:974
description: Mixed, incl. Establishment of competence for transformation, and Thioredoxin-like superfamily
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:974_Mixed,_incl._Establishment_of_competence_for_transformation,_and_Thioredoxin-like_superfamily


id: CL:975
description: Mixed, incl. Establishment of competence for transformation, and Thioredoxin-like superfamily
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:975_Mixed,_incl._Establishment_of_competence_for_transformation,_and_Thioredoxin-like_superfamily


id: CL:977
description: Mixed, incl. Thioredoxin-like superfamily, and Establishment of competence for transformation
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:977_Mixed,_incl._Thioredoxin-like_superfamily,_and_Establishment_of_competence_for_transformation


id: CL:979
description: Mixed, incl. DivIVA family, and N-6 DNA Methylase
name:
  Local Network Cluster (STRING).STRING_v12.0_525309_STRINGid_CL:979_Mixed,_incl._DivIVA_family,_and_N-6_DNA_Methylase


id: GO:0000716
description: Transcription-coupled nucleotide-excision repair, DNA damage recognition
memo: https://amigo.geneontology.org/amigo/term/GO:0000716
golevel: 10
name:
  GOBP.STRING_v12.0_525309_STRINGid_GO:0000716_Transcription-coupled_nucleotide-excision_repair,_DNA_damage_recognition


id: GO:0000724
description: Double-strand break repair via homologous recombination
memo: https://amigo.geneontology.org/amigo/term/GO:0000724
golevel: 9
name:
  GOBP.STRING_v12.0_525309_STRINGid_GO:0000724_Double-strand_break_repair_via_homologous_recombination


id: GO:0001073
description: Transcription antitermination factor activity, DNA binding
memo: https://amigo.geneontology.org/amigo/term/GO:0001073
golevel: 2
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0001073_Transcription_antitermination_factor_activity,_DNA_binding


id: GO:0003871
description: 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity
memo: https://amigo.geneontology.org/amigo/term/GO:0003871
golevel: 6
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0003871_5-methyltetrahydropteroyltriglutamate-homocysteine_S-methyltransferase_activity


id: GO:0003906
description: DNA-(apurinic or apyrimidinic site) endonuclease activity
memo: https://amigo.geneontology.org/amigo/term/GO:0003906
golevel: 4
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0003906_DNA-(apurinic_or_apyrimidinic_site)_endonuclease_activity


id: GO:0003917
description: DNA topoisomerase type I (single strand cut, ATP-independent) activity
memo: https://amigo.geneontology.org/amigo/term/GO:0003917
golevel: 5
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0003917_DNA_topoisomerase_type_I_(single_strand_cut,_ATP-independent)_activity


id: GO:0003918
description: DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
memo: https://amigo.geneontology.org/amigo/term/GO:0003918
golevel: 5
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0003918_DNA_topoisomerase_type_II_(double_strand_cut,_ATP-hydrolyzing)_activity


id: GO:0004018
description: N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity
memo: https://amigo.geneontology.org/amigo/term/GO:0004018
golevel: 5
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0004018_N6-(1,2-dicarboxyethyl)AMP_AMP-lyase_(fumarate-forming)_activity


id: GO:0004088
description: Carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
memo: https://amigo.geneontology.org/amigo/term/GO:0004088
golevel: 5
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0004088_Carbamoyl-phosphate_synthase_(glutamine-hydrolyzing)_activity


id: GO:0004316
description: 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
memo: https://amigo.geneontology.org/amigo/term/GO:0004316
golevel: 6
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0004316_3-oxoacyl-[acyl-carrier-protein]_reductase_(NADPH)_activity


id: GO:0004317
description: 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity
memo: https://amigo.geneontology.org/amigo/term/GO:0004317
golevel: 6
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0004317_3-hydroxypalmitoyl-[acyl-carrier-protein]_dehydratase_activity


id: GO:0004360
description: glutamine-fructose-6-phosphate transaminase (isomerizing) activity
memo: https://amigo.geneontology.org/amigo/term/GO:0004360
golevel: 6
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0004360_glutamine-fructose-6-phosphate_transaminase_(isomerizing)_activity


id: GO:0004486
description: Methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity
memo: https://amigo.geneontology.org/amigo/term/GO:0004486
golevel: 5
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0004486_Methylenetetrahydrofolate_dehydrogenase_[NAD(P)+]_activity


id: GO:0004488
description: Methylenetetrahydrofolate dehydrogenase (NADP+) activity
memo: https://amigo.geneontology.org/amigo/term/GO:0004488
golevel: 6
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0004488_Methylenetetrahydrofolate_dehydrogenase_(NADP+)_activity


id: GO:0004514
description: Nicotinate-nucleotide diphosphorylase (carboxylating) activity
memo: https://amigo.geneontology.org/amigo/term/GO:0004514
golevel: 5
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0004514_Nicotinate-nucleotide_diphosphorylase_(carboxylating)_activity


id: GO:0004616
description: Phosphogluconate dehydrogenase (decarboxylating) activity
memo: https://amigo.geneontology.org/amigo/term/GO:0004616
golevel: 5
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0004616_Phosphogluconate_dehydrogenase_(decarboxylating)_activity


id: GO:0004639
description: Phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
memo: https://amigo.geneontology.org/amigo/term/GO:0004639
golevel: 5
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0004639_Phosphoribosylaminoimidazolesuccinocarboxamide_synthase_activity


id: GO:0004641
description: Phosphoribosylformylglycinamidine cyclo-ligase activity
memo: https://amigo.geneontology.org/amigo/term/GO:0004641
golevel: 5
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0004641_Phosphoribosylformylglycinamidine_cyclo-ligase_activity


id: GO:0004643
description: Phosphoribosylaminoimidazolecarboxamide formyltransferase activity
memo: https://amigo.geneontology.org/amigo/term/GO:0004643
golevel: 5
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0004643_Phosphoribosylaminoimidazolecarboxamide_formyltransferase_activity


id: GO:0004648
description: O-phospho-L-serine:2-oxoglutarate aminotransferase activity
memo: https://amigo.geneontology.org/amigo/term/GO:0004648
golevel: 5
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0004648_O-phospho-L-serine:2-oxoglutarate_aminotransferase_activity


id: GO:0004748
description: Ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
memo: https://amigo.geneontology.org/amigo/term/GO:0004748
golevel: 6
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0004748_Ribonucleoside-diphosphate_reductase_activity,_thioredoxin_disulfide_as_acceptor


id: GO:0006614
description: SRP-dependent cotranslational protein targeting to membrane
memo: https://amigo.geneontology.org/amigo/term/GO:0006614
golevel: 11
name:
  GOBP.STRING_v12.0_525309_STRINGid_GO:0006614_SRP-dependent_cotranslational_protein_targeting_to_membrane


id: GO:0006620
description: Post-translational protein targeting to endoplasmic reticulum membrane
memo: https://amigo.geneontology.org/amigo/term/GO:0006620
golevel: 10
name:
  GOBP.STRING_v12.0_525309_STRINGid_GO:0006620_Post-translational_protein_targeting_to_endoplasmic_reticulum_membrane


id: GO:0008108
description: UDP-glucose:hexose-1-phosphate uridylyltransferase activity
memo: https://amigo.geneontology.org/amigo/term/GO:0008108
golevel: 6
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0008108_UDP-glucose:hexose-1-phosphate_uridylyltransferase_activity


id: GO:0008263
description: Pyrimidine-specific mismatch base pair DNA N-glycosylase activity
memo: https://amigo.geneontology.org/amigo/term/GO:0008263
golevel: 7
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0008263_Pyrimidine-specific_mismatch_base_pair_DNA_N-glycosylase_activity


id: GO:0008444
description: CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity
memo: https://amigo.geneontology.org/amigo/term/GO:0008444
golevel: 6
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0008444_CDP-diacylglycerol-glycerol-3-phosphate_3-phosphatidyltransferase_activity


id: GO:0008534
description: Oxidized purine nucleobase lesion DNA N-glycosylase activity
memo: https://amigo.geneontology.org/amigo/term/GO:0008534
golevel: 7
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0008534_Oxidized_purine_nucleobase_lesion_DNA_N-glycosylase_activity


id: GO:0008659
description: (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity
memo: https://amigo.geneontology.org/amigo/term/GO:0008659
golevel: 5
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0008659_(3R)-hydroxymyristoyl-[acyl-carrier-protein]_dehydratase_activity


id: GO:0008693
description: 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity
memo: https://amigo.geneontology.org/amigo/term/GO:0008693
golevel: 6
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0008693_3-hydroxydecanoyl-[acyl-carrier-protein]_dehydratase_activity


id: GO:0008703
description: 5-amino-6-(5-phosphoribosylamino)uracil reductase activity
memo: https://amigo.geneontology.org/amigo/term/GO:0008703
golevel: 5
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0008703_5-amino-6-(5-phosphoribosylamino)uracil_reductase_activity


id: GO:0008757
description: S-adenosylmethionine-dependent methyltransferase activity
memo: https://amigo.geneontology.org/amigo/term/GO:0008757
golevel: 5
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0008757_S-adenosylmethionine-dependent_methyltransferase_activity


id: GO:0008760
description: UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity
memo: https://amigo.geneontology.org/amigo/term/GO:0008760
golevel: 4
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0008760_UDP-N-acetylglucosamine_1-carboxyvinyltransferase_activity


id: GO:0008764
description: UDP-N-acetylmuramoylalanine-D-glutamate ligase activity
memo: https://amigo.geneontology.org/amigo/term/GO:0008764
golevel: 5
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0008764_UDP-N-acetylmuramoylalanine-D-glutamate_ligase_activity


id: GO:0008766
description: UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
memo: https://amigo.geneontology.org/amigo/term/GO:0008766
golevel: 5
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0008766_UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine_ligase_activity


id: GO:0008835
description: Diaminohydroxyphosphoribosylaminopyrimidine deaminase activity
memo: https://amigo.geneontology.org/amigo/term/GO:0008835
golevel: 5
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0008835_Diaminohydroxyphosphoribosylaminopyrimidine_deaminase_activity


id: GO:0008961
description: Phosphatidylglycerol-prolipoprotein diacylglyceryl transferase activity
memo: https://amigo.geneontology.org/amigo/term/GO:0008961
golevel: 4
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0008961_Phosphatidylglycerol-prolipoprotein_diacylglyceryl_transferase_activity


id: GO:0008963
description: phospho-N-acetylmuramoyl-pentapeptide-transferase activity
memo: https://amigo.geneontology.org/amigo/term/GO:0008963
golevel: 5
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0008963_phospho-N-acetylmuramoyl-pentapeptide-transferase_activity


id: GO:0008965
description: Phosphoenolpyruvate-protein phosphotransferase activity
memo: https://amigo.geneontology.org/amigo/term/GO:0008965
golevel: 5
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0008965_Phosphoenolpyruvate-protein_phosphotransferase_activity


id: GO:0008982
description: protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
memo: https://amigo.geneontology.org/amigo/term/GO:0008982
golevel: 5
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0008982_protein-N(PI)-phosphohistidine-sugar_phosphotransferase_activity


id: GO:0009007
description: Site-specific DNA-methyltransferase (adenine-specific) activity
memo: https://amigo.geneontology.org/amigo/term/GO:0009007
golevel: 6
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0009007_Site-specific_DNA-methyltransferase_(adenine-specific)_activity


id: GO:0009130
description: Pyrimidine nucleoside monophosphate biosynthetic process
memo: https://amigo.geneontology.org/amigo/term/GO:0009130
golevel: 9
name:
  GOBP.STRING_v12.0_525309_STRINGid_GO:0009130_Pyrimidine_nucleoside_monophosphate_biosynthetic_process


id: GO:0009148
description: Pyrimidine nucleoside triphosphate biosynthetic process
memo: https://amigo.geneontology.org/amigo/term/GO:0009148
golevel: 9
name:
  GOBP.STRING_v12.0_525309_STRINGid_GO:0009148_Pyrimidine_nucleoside_triphosphate_biosynthetic_process


id: GO:0009168
description: Purine ribonucleoside monophosphate biosynthetic process
memo: https://amigo.geneontology.org/amigo/term/GO:0009168
golevel: 10
name:
  GOBP.STRING_v12.0_525309_STRINGid_GO:0009168_Purine_ribonucleoside_monophosphate_biosynthetic_process


id: GO:0009173
description: Pyrimidine ribonucleoside monophosphate metabolic process
memo: https://amigo.geneontology.org/amigo/term/GO:0009173
golevel: 9
name:
  GOBP.STRING_v12.0_525309_STRINGid_GO:0009173_Pyrimidine_ribonucleoside_monophosphate_metabolic_process


id: GO:0009174
description: Pyrimidine ribonucleoside monophosphate biosynthetic process
memo: https://amigo.geneontology.org/amigo/term/GO:0009174
golevel: 10
name:
  GOBP.STRING_v12.0_525309_STRINGid_GO:0009174_Pyrimidine_ribonucleoside_monophosphate_biosynthetic_process


id: GO:0009176
description: Pyrimidine deoxyribonucleoside monophosphate metabolic process
memo: https://amigo.geneontology.org/amigo/term/GO:0009176
golevel: 9
name:
  GOBP.STRING_v12.0_525309_STRINGid_GO:0009176_Pyrimidine_deoxyribonucleoside_monophosphate_metabolic_process


id: GO:0009177
description: Pyrimidine deoxyribonucleoside monophosphate biosynthetic process
memo: https://amigo.geneontology.org/amigo/term/GO:0009177
golevel: 10
name:
  GOBP.STRING_v12.0_525309_STRINGid_GO:0009177_Pyrimidine_deoxyribonucleoside_monophosphate_biosynthetic_process


id: GO:0009196
description: Pyrimidine deoxyribonucleoside diphosphate metabolic process
memo: https://amigo.geneontology.org/amigo/term/GO:0009196
golevel: 9
name:
  GOBP.STRING_v12.0_525309_STRINGid_GO:0009196_Pyrimidine_deoxyribonucleoside_diphosphate_metabolic_process


id: GO:0009197
description: Pyrimidine deoxyribonucleoside diphosphate biosynthetic process
memo: https://amigo.geneontology.org/amigo/term/GO:0009197
golevel: 10
name:
  GOBP.STRING_v12.0_525309_STRINGid_GO:0009197_Pyrimidine_deoxyribonucleoside_diphosphate_biosynthetic_process


id: GO:0009206
description: Purine ribonucleoside triphosphate biosynthetic process
memo: https://amigo.geneontology.org/amigo/term/GO:0009206
golevel: 10
name:
  GOBP.STRING_v12.0_525309_STRINGid_GO:0009206_Purine_ribonucleoside_triphosphate_biosynthetic_process


id: GO:0009208
description: Pyrimidine ribonucleoside triphosphate metabolic process
memo: https://amigo.geneontology.org/amigo/term/GO:0009208
golevel: 9
name:
  GOBP.STRING_v12.0_525309_STRINGid_GO:0009208_Pyrimidine_ribonucleoside_triphosphate_metabolic_process


id: GO:0009209
description: Pyrimidine ribonucleoside triphosphate biosynthetic process
memo: https://amigo.geneontology.org/amigo/term/GO:0009209
golevel: 10
name:
  GOBP.STRING_v12.0_525309_STRINGid_GO:0009209_Pyrimidine_ribonucleoside_triphosphate_biosynthetic_process


id: GO:0009211
description: Pyrimidine deoxyribonucleoside triphosphate metabolic process
memo: https://amigo.geneontology.org/amigo/term/GO:0009211
golevel: 9
name:
  GOBP.STRING_v12.0_525309_STRINGid_GO:0009211_Pyrimidine_deoxyribonucleoside_triphosphate_metabolic_process


id: GO:0009212
description: Pyrimidine deoxyribonucleoside triphosphate biosynthetic process
memo: https://amigo.geneontology.org/amigo/term/GO:0009212
golevel: 10
name:
  GOBP.STRING_v12.0_525309_STRINGid_GO:0009212_Pyrimidine_deoxyribonucleoside_triphosphate_biosynthetic_process


id: GO:0009213
description: Pyrimidine deoxyribonucleoside triphosphate catabolic process
memo: https://amigo.geneontology.org/amigo/term/GO:0009213
golevel: 10
name:
  GOBP.STRING_v12.0_525309_STRINGid_GO:0009213_Pyrimidine_deoxyribonucleoside_triphosphate_catabolic_process


id: GO:0009215
description: Purine deoxyribonucleoside triphosphate metabolic process
memo: https://amigo.geneontology.org/amigo/term/GO:0009215
golevel: 9
name:
  GOBP.STRING_v12.0_525309_STRINGid_GO:0009215_Purine_deoxyribonucleoside_triphosphate_metabolic_process


id: GO:0009217
description: Purine deoxyribonucleoside triphosphate catabolic process
memo: https://amigo.geneontology.org/amigo/term/GO:0009217
golevel: 10
name:
  GOBP.STRING_v12.0_525309_STRINGid_GO:0009217_Purine_deoxyribonucleoside_triphosphate_catabolic_process


id: GO:0009401
description: Phosphoenolpyruvate-dependent sugar phosphotransferase system
memo: https://amigo.geneontology.org/amigo/term/GO:0009401
golevel: 8
name:
  GOBP.STRING_v12.0_525309_STRINGid_GO:0009401_Phosphoenolpyruvate-dependent_sugar_phosphotransferase_system


id: GO:0009678
description: Pyrophosphate hydrolysis-driven proton transmembrane transporter activity
memo: https://amigo.geneontology.org/amigo/term/GO:0009678
golevel: 6
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0009678_Pyrophosphate_hydrolysis-driven_proton_transmembrane_transporter_activity


id: GO:0010142
description: Farnesyl diphosphate biosynthetic process, mevalonate pathway
memo: https://amigo.geneontology.org/amigo/term/GO:0010142
golevel: 9
name:
  GOBP.STRING_v12.0_525309_STRINGid_GO:0010142_Farnesyl_diphosphate_biosynthetic_process,_mevalonate_pathway


id: GO:0010557
description: Positive regulation of macromolecule biosynthetic process
memo: https://amigo.geneontology.org/amigo/term/GO:0010557
golevel: 6
name:
  GOBP.STRING_v12.0_525309_STRINGid_GO:0010557_Positive_regulation_of_macromolecule_biosynthetic_process


id: GO:0010558
description: Negative regulation of macromolecule biosynthetic process
memo: https://amigo.geneontology.org/amigo/term/GO:0010558
golevel: 6
name:
  GOBP.STRING_v12.0_525309_STRINGid_GO:0010558_Negative_regulation_of_macromolecule_biosynthetic_process


id: GO:0015318
description: Inorganic molecular entity transmembrane transporter activity
memo: https://amigo.geneontology.org/amigo/term/GO:0015318
golevel: 3
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0015318_Inorganic_molecular_entity_transmembrane_transporter_activity


id: GO:0015355
description: Secondary active monocarboxylate transmembrane transporter activity
memo: https://amigo.geneontology.org/amigo/term/GO:0015355
golevel: 6
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0015355_Secondary_active_monocarboxylate_transmembrane_transporter_activity


id: GO:0015415
description: ATPase-coupled phosphate ion transmembrane transporter activity
memo: https://amigo.geneontology.org/amigo/term/GO:0015415
golevel: 7
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0015415_ATPase-coupled_phosphate_ion_transmembrane_transporter_activity


id: GO:0015453
description: Oxidoreduction-driven active transmembrane transporter activity
memo: https://amigo.geneontology.org/amigo/term/GO:0015453
golevel: 5
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0015453_Oxidoreduction-driven_active_transmembrane_transporter_activity


id: GO:0015658
description: Branched-chain amino acid transmembrane transporter activity
memo: https://amigo.geneontology.org/amigo/term/GO:0015658
golevel: 6
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0015658_Branched-chain_amino_acid_transmembrane_transporter_activity


id: GO:0015932
description: Nucleobase-containing compound transmembrane transporter activity
memo: https://amigo.geneontology.org/amigo/term/GO:0015932
golevel: 3
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0015932_Nucleobase-containing_compound_transmembrane_transporter_activity


id: GO:0016614
description: Oxidoreductase activity, acting on CH-OH group of donors
memo: https://amigo.geneontology.org/amigo/term/GO:0016614
golevel: 3
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0016614_Oxidoreductase_activity,_acting_on_CH-OH_group_of_donors


id: GO:0016616
description: Oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
memo: https://amigo.geneontology.org/amigo/term/GO:0016616
golevel: 4
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0016616_Oxidoreductase_activity,_acting_on_the_CH-OH_group_of_donors,_NAD_or_NADP_as_acceptor


id: GO:0016620
description: Oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
memo: https://amigo.geneontology.org/amigo/term/GO:0016620
golevel: 4
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0016620_Oxidoreductase_activity,_acting_on_the_aldehyde_or_oxo_group_of_donors,_NAD_or_NADP_as_acceptor


id: GO:0016623
description: Oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor
memo: https://amigo.geneontology.org/amigo/term/GO:0016623
golevel: 4
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0016623_Oxidoreductase_activity,_acting_on_the_aldehyde_or_oxo_group_of_donors,_oxygen_as_acceptor


id: GO:0016624
description: Oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
memo: https://amigo.geneontology.org/amigo/term/GO:0016624
golevel: 4
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0016624_Oxidoreductase_activity,_acting_on_the_aldehyde_or_oxo_group_of_donors,_disulfide_as_acceptor


id: GO:0016627
description: Oxidoreductase activity, acting on the CH-CH group of donors
memo: https://amigo.geneontology.org/amigo/term/GO:0016627
golevel: 3
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0016627_Oxidoreductase_activity,_acting_on_the_CH-CH_group_of_donors


id: GO:0016628
description: Oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
memo: https://amigo.geneontology.org/amigo/term/GO:0016628
golevel: 4
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0016628_Oxidoreductase_activity,_acting_on_the_CH-CH_group_of_donors,_NAD_or_NADP_as_acceptor


id: GO:0016634
description: Oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor
memo: https://amigo.geneontology.org/amigo/term/GO:0016634
golevel: 4
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0016634_Oxidoreductase_activity,_acting_on_the_CH-CH_group_of_donors,_oxygen_as_acceptor


id: GO:0016635
memo: https://amigo.geneontology.org/amigo/term/GO:0016635
golevel: 4
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0016635_Oxidoreductase_activity,_acting_on_the_CH-CH_group_of_donors,_quinone_or_related_compound_as_acceptor

description:
  Oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor


id: GO:0016638
description: Oxidoreductase activity, acting on the CH-NH2 group of donors
memo: https://amigo.geneontology.org/amigo/term/GO:0016638
golevel: 3
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0016638_Oxidoreductase_activity,_acting_on_the_CH-NH2_group_of_donors


id: GO:0016639
description: Oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor
memo: https://amigo.geneontology.org/amigo/term/GO:0016639
golevel: 4
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0016639_Oxidoreductase_activity,_acting_on_the_CH-NH2_group_of_donors,_NAD_or_NADP_as_acceptor


id: GO:0016645
description: Oxidoreductase activity, acting on the CH-NH group of donors
memo: https://amigo.geneontology.org/amigo/term/GO:0016645
golevel: 3
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0016645_Oxidoreductase_activity,_acting_on_the_CH-NH_group_of_donors


id: GO:0016646
description: Oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor
memo: https://amigo.geneontology.org/amigo/term/GO:0016646
golevel: 4
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0016646_Oxidoreductase_activity,_acting_on_the_CH-NH_group_of_donors,_NAD_or_NADP_as_acceptor


id: GO:0016652
description: Oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor
memo: https://amigo.geneontology.org/amigo/term/GO:0016652
golevel: 4
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0016652_Oxidoreductase_activity,_acting_on_NAD(P)H,_NAD(P)_as_acceptor


id: GO:0016655
description: Oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
memo: https://amigo.geneontology.org/amigo/term/GO:0016655
golevel: 4
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0016655_Oxidoreductase_activity,_acting_on_NAD(P)H,_quinone_or_similar_compound_as_acceptor


id: GO:0016657
description: Oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor
memo: https://amigo.geneontology.org/amigo/term/GO:0016657
golevel: 4
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0016657_Oxidoreductase_activity,_acting_on_NAD(P)H,_nitrogenous_group_as_acceptor


id: GO:0016661
description: Oxidoreductase activity, acting on other nitrogenous compounds as donors
memo: https://amigo.geneontology.org/amigo/term/GO:0016661
golevel: 3
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0016661_Oxidoreductase_activity,_acting_on_other_nitrogenous_compounds_as_donors


id: GO:0016667
description: Oxidoreductase activity, acting on a sulfur group of donors
memo: https://amigo.geneontology.org/amigo/term/GO:0016667
golevel: 3
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0016667_Oxidoreductase_activity,_acting_on_a_sulfur_group_of_donors


id: GO:0016668
description: Oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor
memo: https://amigo.geneontology.org/amigo/term/GO:0016668
golevel: 4
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0016668_Oxidoreductase_activity,_acting_on_a_sulfur_group_of_donors,_NAD(P)_as_acceptor


id: GO:0016671
description: Oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor
memo: https://amigo.geneontology.org/amigo/term/GO:0016671
golevel: 4
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0016671_Oxidoreductase_activity,_acting_on_a_sulfur_group_of_donors,_disulfide_as_acceptor


id: GO:0016684
description: Oxidoreductase activity, acting on peroxide as acceptor
memo: https://amigo.geneontology.org/amigo/term/GO:0016684
golevel: 3
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0016684_Oxidoreductase_activity,_acting_on_peroxide_as_acceptor


id: GO:0016705
memo: https://amigo.geneontology.org/amigo/term/GO:0016705
golevel: 3
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0016705_Oxidoreductase_activity,_acting_on_paired_donors,_with_incorporation_or_reduction_of_molecular_oxygen

description:
  Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen


id: GO:0016712
memo: https://amigo.geneontology.org/amigo/term/GO:0016712
golevel: 4
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0016712_Oxidoreductase_activity,_acting_on_paired_donors,_with_incorporation_or_reduction_of_molecular_oxygen,_reduced_flavin_or_flavoprotein_as_one_donor,_and_incorporation_of_one_atom_of_oxygen

description:
  Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen


id: GO:0016726
description: Oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor
memo: https://amigo.geneontology.org/amigo/term/GO:0016726
golevel: 4
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0016726_Oxidoreductase_activity,_acting_on_CH_or_CH2_groups,_NAD_or_NADP_as_acceptor


id: GO:0016728
description: Oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor
memo: https://amigo.geneontology.org/amigo/term/GO:0016728
golevel: 4
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0016728_Oxidoreductase_activity,_acting_on_CH_or_CH2_groups,_disulfide_as_acceptor


id: GO:0016730
description: Oxidoreductase activity, acting on iron-sulfur proteins as donors
memo: https://amigo.geneontology.org/amigo/term/GO:0016730
golevel: 3
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0016730_Oxidoreductase_activity,_acting_on_iron-sulfur_proteins_as_donors


id: GO:0016731
description: Oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor
memo: https://amigo.geneontology.org/amigo/term/GO:0016731
golevel: 4
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0016731_Oxidoreductase_activity,_acting_on_iron-sulfur_proteins_as_donors,_NAD_or_NADP_as_acceptor


id: GO:0016742
description: Hydroxymethyl-, formyl- and related transferase activity
memo: https://amigo.geneontology.org/amigo/term/GO:0016742
golevel: 4
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0016742_Hydroxymethyl-,_formyl-_and_related_transferase_activity


id: GO:0016747
description: Acyltransferase activity, transferring groups other than amino-acyl groups
memo: https://amigo.geneontology.org/amigo/term/GO:0016747
golevel: 4
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0016747_Acyltransferase_activity,_transferring_groups_other_than_amino-acyl_groups


id: GO:0016765
description: Transferase activity, transferring alkyl or aryl (other than methyl) groups
memo: https://amigo.geneontology.org/amigo/term/GO:0016765
golevel: 3
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0016765_Transferase_activity,_transferring_alkyl_or_aryl_(other_than_methyl)_groups


id: GO:0016772
description: Transferase activity, transferring phosphorus-containing groups
memo: https://amigo.geneontology.org/amigo/term/GO:0016772
golevel: 3
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0016772_Transferase_activity,_transferring_phosphorus-containing_groups


id: GO:0016774
description: Phosphotransferase activity, carboxyl group as acceptor
memo: https://amigo.geneontology.org/amigo/term/GO:0016774
golevel: 4
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0016774_Phosphotransferase_activity,_carboxyl_group_as_acceptor


id: GO:0016775
description: Phosphotransferase activity, nitrogenous group as acceptor
memo: https://amigo.geneontology.org/amigo/term/GO:0016775
golevel: 4
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0016775_Phosphotransferase_activity,_nitrogenous_group_as_acceptor


id: GO:0016776
description: Phosphotransferase activity, phosphate group as acceptor
memo: https://amigo.geneontology.org/amigo/term/GO:0016776
golevel: 4
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0016776_Phosphotransferase_activity,_phosphate_group_as_acceptor


id: GO:0016780
description: Phosphotransferase activity, for other substituted phosphate groups
memo: https://amigo.geneontology.org/amigo/term/GO:0016780
golevel: 4
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0016780_Phosphotransferase_activity,_for_other_substituted_phosphate_groups


id: GO:0016782
description: Transferase activity, transferring sulphur-containing groups
memo: https://amigo.geneontology.org/amigo/term/GO:0016782
golevel: 3
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0016782_Transferase_activity,_transferring_sulphur-containing_groups


id: GO:0016796
memo: https://amigo.geneontology.org/amigo/term/GO:0016796
golevel: 6
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0016796_Exonuclease_activity,_active_with_either_ribo-_or_deoxyribonucleic_acids_and_producing_5-phosphomonoesters

description:
  Exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5-phosphomonoesters


id: GO:0016810
description: Hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
memo: https://amigo.geneontology.org/amigo/term/GO:0016810
golevel: 3
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0016810_Hydrolase_activity,_acting_on_carbon-nitrogen_(but_not_peptide)_bonds


id: GO:0016811
description: Hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
memo: https://amigo.geneontology.org/amigo/term/GO:0016811
golevel: 4
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0016811_Hydrolase_activity,_acting_on_carbon-nitrogen_(but_not_peptide)_bonds,_in_linear_amides


id: GO:0016812
description: Hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
memo: https://amigo.geneontology.org/amigo/term/GO:0016812
golevel: 4
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0016812_Hydrolase_activity,_acting_on_carbon-nitrogen_(but_not_peptide)_bonds,_in_cyclic_amides


id: GO:0016814
description: Hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
memo: https://amigo.geneontology.org/amigo/term/GO:0016814
golevel: 4
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0016814_Hydrolase_activity,_acting_on_carbon-nitrogen_(but_not_peptide)_bonds,_in_cyclic_amidines


id: GO:0016818
description: Hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
memo: https://amigo.geneontology.org/amigo/term/GO:0016818
golevel: 4
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0016818_Hydrolase_activity,_acting_on_acid_anhydrides,_in_phosphorus-containing_anhydrides


id: GO:0016855
description: Racemase and epimerase activity, acting on amino acids and derivatives
memo: https://amigo.geneontology.org/amigo/term/GO:0016855
golevel: 4
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0016855_Racemase_and_epimerase_activity,_acting_on_amino_acids_and_derivatives


id: GO:0016857
description: Racemase and epimerase activity, acting on carbohydrates and derivatives
memo: https://amigo.geneontology.org/amigo/term/GO:0016857
golevel: 4
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0016857_Racemase_and_epimerase_activity,_acting_on_carbohydrates_and_derivatives


id: GO:0016861
description: Intramolecular oxidoreductase activity, interconverting aldoses and ketoses
memo: https://amigo.geneontology.org/amigo/term/GO:0016861
golevel: 4
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0016861_Intramolecular_oxidoreductase_activity,_interconverting_aldoses_and_ketoses


id: GO:0016863
description: Intramolecular oxidoreductase activity, transposing C=C bonds
memo: https://amigo.geneontology.org/amigo/term/GO:0016863
golevel: 4
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0016863_Intramolecular_oxidoreductase_activity,_transposing_C=C_bonds


id: GO:0016868
description: Intramolecular transferase activity, phosphotransferases
memo: https://amigo.geneontology.org/amigo/term/GO:0016868
golevel: 4
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0016868_Intramolecular_transferase_activity,_phosphotransferases


id: GO:0016884
description: Carbon-nitrogen ligase activity, with glutamine as amido-N-donor
memo: https://amigo.geneontology.org/amigo/term/GO:0016884
golevel: 4
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0016884_Carbon-nitrogen_ligase_activity,_with_glutamine_as_amido-N-donor


id: GO:0016888
description: Endodeoxyribonuclease activity, producing 5-phosphomonoesters
memo: https://amigo.geneontology.org/amigo/term/GO:0016888
golevel: 7
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0016888_Endodeoxyribonuclease_activity,_producing_5-phosphomonoesters


id: GO:0016889
description: Endodeoxyribonuclease activity, producing 3-phosphomonoesters
memo: https://amigo.geneontology.org/amigo/term/GO:0016889
golevel: 7
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0016889_Endodeoxyribonuclease_activity,_producing_3-phosphomonoesters


id: GO:0016891
description: Endoribonuclease activity, producing 5-phosphomonoesters
memo: https://amigo.geneontology.org/amigo/term/GO:0016891
golevel: 7
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0016891_Endoribonuclease_activity,_producing_5-phosphomonoesters


id: GO:0016893
memo: https://amigo.geneontology.org/amigo/term/GO:0016893
golevel: 6
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0016893_Endonuclease_activity,_active_with_either_ribo-_or_deoxyribonucleic_acids_and_producing_5-phosphomonoesters

description:
  Endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5-phosphomonoesters


id: GO:0016894
memo: https://amigo.geneontology.org/amigo/term/GO:0016894
golevel: 6
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0016894_Endonuclease_activity,_active_with_either_ribo-_or_deoxyribonucleic_acids_and_producing_3-phosphomonoesters

description:
  Endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3-phosphomonoesters


id: GO:0016895
description: Exodeoxyribonuclease activity, producing 5-phosphomonoesters
memo: https://amigo.geneontology.org/amigo/term/GO:0016895
golevel: 7
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0016895_Exodeoxyribonuclease_activity,_producing_5-phosphomonoesters


id: GO:0016896
description: Exoribonuclease activity, producing 5-phosphomonoesters
memo: https://amigo.geneontology.org/amigo/term/GO:0016896
golevel: 7
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0016896_Exoribonuclease_activity,_producing_5-phosphomonoesters


id: GO:0016903
description: Oxidoreductase activity, acting on the aldehyde or oxo group of donors
memo: https://amigo.geneontology.org/amigo/term/GO:0016903
golevel: 3
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0016903_Oxidoreductase_activity,_acting_on_the_aldehyde_or_oxo_group_of_donors


id: GO:0019171
description: 3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity
memo: https://amigo.geneontology.org/amigo/term/GO:0019171
golevel: 5
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0019171_3-hydroxyacyl-[acyl-carrier-protein]_dehydratase_activity


id: GO:0019219
description: Regulation of nucleobase-containing compound metabolic process
memo: https://amigo.geneontology.org/amigo/term/GO:0019219
golevel: 5
name:
  GOBP.STRING_v12.0_525309_STRINGid_GO:0019219_Regulation_of_nucleobase-containing_compound_metabolic_process


id: GO:0019287
description: Isopentenyl diphosphate biosynthetic process, mevalonate pathway
memo: https://amigo.geneontology.org/amigo/term/GO:0019287
golevel: 12
name:
  GOBP.STRING_v12.0_525309_STRINGid_GO:0019287_Isopentenyl_diphosphate_biosynthetic_process,_mevalonate_pathway


id: GO:0019288
description: Isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway
memo: https://amigo.geneontology.org/amigo/term/GO:0019288
golevel: 8
name:
  GOBP.STRING_v12.0_525309_STRINGid_GO:0019288_Isopentenyl_diphosphate_biosynthetic_process,_methylerythritol_4-phosphate_pathway


id: GO:0019829
description: ATPase-coupled cation transmembrane transporter activity
memo: https://amigo.geneontology.org/amigo/term/GO:0019829
golevel: 6
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0019829_ATPase-coupled_cation_transmembrane_transporter_activity


id: GO:0030613
description: Oxidoreductase activity, acting on phosphorus or arsenic in donors
memo: https://amigo.geneontology.org/amigo/term/GO:0030613
golevel: 3
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0030613_Oxidoreductase_activity,_acting_on_phosphorus_or_arsenic_in_donors


id: GO:0030614
description: Oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor
memo: https://amigo.geneontology.org/amigo/term/GO:0030614
golevel: 4
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0030614_Oxidoreductase_activity,_acting_on_phosphorus_or_arsenic_in_donors,_disulfide_as_acceptor


id: GO:0031250
description: Anaerobic ribonucleoside-triphosphate reductase complex
memo: https://amigo.geneontology.org/amigo/term/GO:0031250
golevel: 4
name:
  GOCC.STRING_v12.0_525309_STRINGid_GO:0031250_Anaerobic_ribonucleoside-triphosphate_reductase_complex


id: GO:0032105
description: Negative regulation of response to extracellular stimulus
memo: https://amigo.geneontology.org/amigo/term/GO:0032105
golevel: 6
name:
  GOBP.STRING_v12.0_525309_STRINGid_GO:0032105_Negative_regulation_of_response_to_extracellular_stimulus


id: GO:0032297
description: Negative regulation of DNA-templated DNA replication initiation
memo: https://amigo.geneontology.org/amigo/term/GO:0032297
golevel: 11
name:
  GOBP.STRING_v12.0_525309_STRINGid_GO:0032297_Negative_regulation_of_DNA-templated_DNA_replication_initiation


id: GO:0032414
description: Positive regulation of ion transmembrane transporter activity
memo: https://amigo.geneontology.org/amigo/term/GO:0032414
golevel: 8
name:
  GOBP.STRING_v12.0_525309_STRINGid_GO:0032414_Positive_regulation_of_ion_transmembrane_transporter_activity


id: GO:0033177
description: Proton-transporting two-sector ATPase complex, proton-transporting domain
memo: https://amigo.geneontology.org/amigo/term/GO:0033177
golevel: 3
name:
  GOCC.STRING_v12.0_525309_STRINGid_GO:0033177_Proton-transporting_two-sector_ATPase_complex,_proton-transporting_domain


id: GO:0033178
description: Proton-transporting two-sector ATPase complex, catalytic domain
memo: https://amigo.geneontology.org/amigo/term/GO:0033178
golevel: 3
name:
  GOCC.STRING_v12.0_525309_STRINGid_GO:0033178_Proton-transporting_two-sector_ATPase_complex,_catalytic_domain


id: GO:0033283
description: ATPase-coupled organic acid transmembrane transporter activity
memo: https://amigo.geneontology.org/amigo/term/GO:0033283
golevel: 6
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0033283_ATPase-coupled_organic_acid_transmembrane_transporter_activity


id: GO:0033284
description: ATPase-coupled carboxylic acid transmembrane transporter activity
memo: https://amigo.geneontology.org/amigo/term/GO:0033284
golevel: 7
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0033284_ATPase-coupled_carboxylic_acid_transmembrane_transporter_activity


id: GO:0033744
description: L-methionine:thioredoxin-disulfide S-oxidoreductase activity
memo: https://amigo.geneontology.org/amigo/term/GO:0033744
golevel: 5
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0033744_L-methionine:thioredoxin-disulfide_S-oxidoreductase_activity


id: GO:0033818
description: Beta-ketoacyl-acyl-carrier-protein synthase III activity
memo: https://amigo.geneontology.org/amigo/term/GO:0033818
golevel: 5
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0033818_Beta-ketoacyl-acyl-carrier-protein_synthase_III_activity


id: GO:0034023
description: 5-(carboxyamino)imidazole ribonucleotide mutase activity
memo: https://amigo.geneontology.org/amigo/term/GO:0034023
golevel: 4
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0034023_5-(carboxyamino)imidazole_ribonucleotide_mutase_activity


id: GO:0034036
description: Purine ribonucleoside bisphosphate biosynthetic process
memo: https://amigo.geneontology.org/amigo/term/GO:0034036
golevel: 10
name:
  GOBP.STRING_v12.0_525309_STRINGid_GO:0034036_Purine_ribonucleoside_bisphosphate_biosynthetic_process


id: GO:0034249
description: Negative regulation of cellular amide metabolic process
memo: https://amigo.geneontology.org/amigo/term/GO:0034249
golevel: 6
name:
  GOBP.STRING_v12.0_525309_STRINGid_GO:0034249_Negative_regulation_of_cellular_amide_metabolic_process


id: GO:0034250
description: Positive regulation of cellular amide metabolic process
memo: https://amigo.geneontology.org/amigo/term/GO:0034250
golevel: 6
name:
  GOBP.STRING_v12.0_525309_STRINGid_GO:0034250_Positive_regulation_of_cellular_amide_metabolic_process


id: GO:0034257
description: Nicotinamide riboside transmembrane transporter activity
memo: https://amigo.geneontology.org/amigo/term/GO:0034257
golevel: 5
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0034257_Nicotinamide_riboside_transmembrane_transporter_activity


id: GO:0034404
description: Nucleobase-containing small molecule biosynthetic process
memo: https://amigo.geneontology.org/amigo/term/GO:0034404
golevel: 6
name:
  GOBP.STRING_v12.0_525309_STRINGid_GO:0034404_Nucleobase-containing_small_molecule_biosynthetic_process


id: GO:0035592
description: Establishment of protein localization to extracellular region
memo: https://amigo.geneontology.org/amigo/term/GO:0035592
golevel: 6
name:
  GOBP.STRING_v12.0_525309_STRINGid_GO:0035592_Establishment_of_protein_localization_to_extracellular_region


id: GO:0036361
description: Racemase activity, acting on amino acids and derivatives
memo: https://amigo.geneontology.org/amigo/term/GO:0036361
golevel: 5
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0036361_Racemase_activity,_acting_on_amino_acids_and_derivatives


id: GO:0042083
description: 5,10-methylenetetrahydrofolate-dependent methyltransferase activity
memo: https://amigo.geneontology.org/amigo/term/GO:0042083
golevel: 5
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0042083_5,10-methylenetetrahydrofolate-dependent_methyltransferase_activity


id: GO:0042085
description: 5-methyltetrahydropteroyltri-L-glutamate-dependent methyltransferase activity
memo: https://amigo.geneontology.org/amigo/term/GO:0042085
golevel: 5
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0042085_5-methyltetrahydropteroyltri-L-glutamate-dependent_methyltransferase_activity


id: GO:0042173
description: Regulation of sporulation resulting in formation of a cellular spore
memo: https://amigo.geneontology.org/amigo/term/GO:0042173
golevel: 6
name:
  GOBP.STRING_v12.0_525309_STRINGid_GO:0042173_Regulation_of_sporulation_resulting_in_formation_of_a_cellular_spore


id: GO:0042174
description: Negative regulation of sporulation resulting in formation of a cellular spore
memo: https://amigo.geneontology.org/amigo/term/GO:0042174
golevel: 7
name:
  GOBP.STRING_v12.0_525309_STRINGid_GO:0042174_Negative_regulation_of_sporulation_resulting_in_formation_of_a_cellular_spore


id: GO:0042777
description: Proton motive force-driven plasma membrane ATP synthesis
memo: https://amigo.geneontology.org/amigo/term/GO:0042777
golevel: 13
name:
  GOBP.STRING_v12.0_525309_STRINGid_GO:0042777_Proton_motive_force-driven_plasma_membrane_ATP_synthesis


id: GO:0043225
description: ATPase-coupled inorganic anion transmembrane transporter activity
memo: https://amigo.geneontology.org/amigo/term/GO:0043225
golevel: 6
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0043225_ATPase-coupled_inorganic_anion_transmembrane_transporter_activity


id: GO:0043242
description: Negative regulation of protein-containing complex disassembly
memo: https://amigo.geneontology.org/amigo/term/GO:0043242
golevel: 7
name:
  GOBP.STRING_v12.0_525309_STRINGid_GO:0043242_Negative_regulation_of_protein-containing_complex_disassembly


id: GO:0043365
description: [formate-C-acetyltransferase]-activating enzyme activity
memo: https://amigo.geneontology.org/amigo/term/GO:0043365
golevel: 4
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0043365_[formate-C-acetyltransferase]-activating_enzyme_activity


id: GO:0043772
description: Acyl-phosphate glycerol-3-phosphate acyltransferase activity
memo: https://amigo.geneontology.org/amigo/term/GO:0043772
golevel: 5
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0043772_Acyl-phosphate_glycerol-3-phosphate_acyltransferase_activity


id: GO:0043811
description: Phosphate:acyl-[acyl carrier protein] acyltransferase activity
memo: https://amigo.geneontology.org/amigo/term/GO:0043811
golevel: 5
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0043811_Phosphate:acyl-[acyl_carrier_protein]_acyltransferase_activity


id: GO:0044419
description: Biological process involved in interspecies interaction between organisms
memo: https://amigo.geneontology.org/amigo/term/GO:0044419
golevel: 1
name:
  GOBP.STRING_v12.0_525309_STRINGid_GO:0044419_Biological_process_involved_in_interspecies_interaction_between_organisms


id: GO:0044769
description: ATPase activity, coupled to transmembrane movement of ions, rotational mechanism
memo: https://amigo.geneontology.org/amigo/term/GO:0044769
golevel: 7
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0044769_ATPase_activity,_coupled_to_transmembrane_movement_of_ions,_rotational_mechanism


id: GO:0045261
description: Proton-transporting ATP synthase complex, catalytic core F(1)
memo: https://amigo.geneontology.org/amigo/term/GO:0045261
golevel: 6
name:
  GOCC.STRING_v12.0_525309_STRINGid_GO:0045261_Proton-transporting_ATP_synthase_complex,_catalytic_core_F(1)


id: GO:0045263
description: Proton-transporting ATP synthase complex, coupling factor F(o)
memo: https://amigo.geneontology.org/amigo/term/GO:0045263
golevel: 6
name:
  GOCC.STRING_v12.0_525309_STRINGid_GO:0045263_Proton-transporting_ATP_synthase_complex,_coupling_factor_F(o)


id: GO:0045304
description: Regulation of establishment of competence for transformation
memo: https://amigo.geneontology.org/amigo/term/GO:0045304
golevel: 6
name:
  GOBP.STRING_v12.0_525309_STRINGid_GO:0045304_Regulation_of_establishment_of_competence_for_transformation


id: GO:0045881
description: Positive regulation of sporulation resulting in formation of a cellular spore
memo: https://amigo.geneontology.org/amigo/term/GO:0045881
golevel: 7
name:
  GOBP.STRING_v12.0_525309_STRINGid_GO:0045881_Positive_regulation_of_sporulation_resulting_in_formation_of_a_cellular_spore


id: GO:0045934
description: Negative regulation of nucleobase-containing compound metabolic process
memo: https://amigo.geneontology.org/amigo/term/GO:0045934
golevel: 6
name:
  GOBP.STRING_v12.0_525309_STRINGid_GO:0045934_Negative_regulation_of_nucleobase-containing_compound_metabolic_process


id: GO:0045935
description: Positive regulation of nucleobase-containing compound metabolic process
memo: https://amigo.geneontology.org/amigo/term/GO:0045935
golevel: 6
name:
  GOBP.STRING_v12.0_525309_STRINGid_GO:0045935_Positive_regulation_of_nucleobase-containing_compound_metabolic_process


id: GO:0045982
description: Negative regulation of purine nucleobase metabolic process
memo: https://amigo.geneontology.org/amigo/term/GO:0045982
golevel: 9
name:
  GOBP.STRING_v12.0_525309_STRINGid_GO:0045982_Negative_regulation_of_purine_nucleobase_metabolic_process


id: GO:0046538
description: 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity
memo: https://amigo.geneontology.org/amigo/term/GO:0046538
golevel: 6
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0046538_2,3-bisphosphoglycerate-dependent_phosphoglycerate_mutase_activity


id: GO:0046912
description: Acyltransferase activity, acyl groups converted into alkyl on transfer
memo: https://amigo.geneontology.org/amigo/term/GO:0046912
golevel: 4
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0046912_Acyltransferase_activity,_acyl_groups_converted_into_alkyl_on_transfer


id: GO:0046915
description: Transition metal ion transmembrane transporter activity
memo: https://amigo.geneontology.org/amigo/term/GO:0046915
golevel: 6
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0046915_Transition_metal_ion_transmembrane_transporter_activity


id: GO:0046933
description: Proton-transporting ATP synthase activity, rotational mechanism
memo: https://amigo.geneontology.org/amigo/term/GO:0046933
golevel: 8
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0046933_Proton-transporting_ATP_synthase_activity,_rotational_mechanism


id: GO:0046961
description: Proton-transporting ATPase activity, rotational mechanism
memo: https://amigo.geneontology.org/amigo/term/GO:0046961
golevel: 8
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0046961_Proton-transporting_ATPase_activity,_rotational_mechanism


id: GO:0046992
description: Oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond
memo: https://amigo.geneontology.org/amigo/term/GO:0046992
golevel: 3
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0046992_Oxidoreductase_activity,_acting_on_X-H_and_Y-H_to_form_an_X-Y_bond


id: GO:0047451
description: 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
memo: https://amigo.geneontology.org/amigo/term/GO:0047451
golevel: 6
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0047451_3-hydroxyoctanoyl-[acyl-carrier-protein]_dehydratase_activity


id: GO:0047480
description: UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
memo: https://amigo.geneontology.org/amigo/term/GO:0047480
golevel: 5
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0047480_UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine_ligase_activity


id: GO:0048646
description: Anatomical structure formation involved in morphogenesis
memo: https://amigo.geneontology.org/amigo/term/GO:0048646
golevel: 2
name:
  GOBP.STRING_v12.0_525309_STRINGid_GO:0048646_Anatomical_structure_formation_involved_in_morphogenesis


id: GO:0050485
description: Oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with a disulfide as acceptor
memo: https://amigo.geneontology.org/amigo/term/GO:0050485
golevel: 4
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0050485_Oxidoreductase_activity,_acting_on_X-H_and_Y-H_to_form_an_X-Y_bond,_with_a_disulfide_as_acceptor


id: GO:0050486
description: Intramolecular transferase activity, transferring hydroxy groups
memo: https://amigo.geneontology.org/amigo/term/GO:0050486
golevel: 4
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0050486_Intramolecular_transferase_activity,_transferring_hydroxy_groups


id: GO:0050511
description: Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity
memo: https://amigo.geneontology.org/amigo/term/GO:0050511
golevel: 6
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0050511_Undecaprenyldiphospho-muramoylpentapeptide_beta-N-acetylglucosaminyltransferase_activity


id: GO:0050515
description: 4-(cytidine 5-diphospho)-2-C-methyl-D-erythritol kinase activity
memo: https://amigo.geneontology.org/amigo/term/GO:0050515
golevel: 5
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0050515_4-(cytidine_5-diphospho)-2-C-methyl-D-erythritol_kinase_activity


id: GO:0050566
description: asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity
memo: https://amigo.geneontology.org/amigo/term/GO:0050566
golevel: 5
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0050566_asparaginyl-tRNA_synthase_(glutamine-hydrolyzing)_activity


id: GO:0050567
description: glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
memo: https://amigo.geneontology.org/amigo/term/GO:0050567
golevel: 5
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0050567_glutaminyl-tRNA_synthase_(glutamine-hydrolyzing)_activity


id: GO:0051003
description: Ligase activity, forming nitrogen-metal bonds, forming coordination complexes
memo: https://amigo.geneontology.org/amigo/term/GO:0051003
golevel: 4
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0051003_Ligase_activity,_forming_nitrogen-metal_bonds,_forming_coordination_complexes


id: GO:0051172
description: Negative regulation of nitrogen compound metabolic process
memo: https://amigo.geneontology.org/amigo/term/GO:0051172
golevel: 5
name:
  GOBP.STRING_v12.0_525309_STRINGid_GO:0051172_Negative_regulation_of_nitrogen_compound_metabolic_process


id: GO:0051173
description: Positive regulation of nitrogen compound metabolic process
memo: https://amigo.geneontology.org/amigo/term/GO:0051173
golevel: 5
name:
  GOBP.STRING_v12.0_525309_STRINGid_GO:0051173_Positive_regulation_of_nitrogen_compound_metabolic_process


id: GO:0051703
description: Biological process involved in intraspecies interaction between organisms
memo: https://amigo.geneontology.org/amigo/term/GO:0051703
golevel: 1
name:
  GOBP.STRING_v12.0_525309_STRINGid_GO:0051703_Biological_process_involved_in_intraspecies_interaction_between_organisms


id: GO:0051748
description: UTP-monosaccharide-1-phosphate uridylyltransferase activity
memo: https://amigo.geneontology.org/amigo/term/GO:0051748
golevel: 6
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0051748_UTP-monosaccharide-1-phosphate_uridylyltransferase_activity


id: GO:0051991
memo: https://amigo.geneontology.org/amigo/term/GO:0051991
golevel: 6
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0051991_UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol_4-beta-N-acetylglucosaminlytransferase_activity

description:
  UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol 4-beta-N-acetylglucosaminlytransferase activity


id: GO:0051992
memo: https://amigo.geneontology.org/amigo/term/GO:0051992
golevel: 5
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0051992_UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine:undecaprenyl-phosphate_transferase_activity

description:
  UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine:undecaprenyl-phosphate transferase activity


id: GO:0052908
description: 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
memo: https://amigo.geneontology.org/amigo/term/GO:0052908
golevel: 9
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0052908_16S_rRNA_(adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase_activity


id: GO:0052929
description: ATP:3-cytidine-cytidine-tRNA adenylyltransferase activity
memo: https://amigo.geneontology.org/amigo/term/GO:0052929
golevel: 6
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0052929_ATP:3-cytidine-cytidine-tRNA_adenylyltransferase_activity


id: GO:0055052
description: ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
memo: https://amigo.geneontology.org/amigo/term/GO:0055052
golevel: 7
name:
  GOCC.STRING_v12.0_525309_STRINGid_GO:0055052_ATP-binding_cassette_(ABC)_transporter_complex,_substrate-binding_subunit-containing


id: GO:0060567
description: Negative regulation of DNA-templated transcription, termination
memo: https://amigo.geneontology.org/amigo/term/GO:0060567
golevel: 12
name:
  GOBP.STRING_v12.0_525309_STRINGid_GO:0060567_Negative_regulation_of_DNA-templated_transcription,_termination


id: GO:0061695
description: Transferase complex, transferring phosphorus-containing groups
memo: https://amigo.geneontology.org/amigo/term/GO:0061695
golevel: 4
name:
  GOCC.STRING_v12.0_525309_STRINGid_GO:0061695_Transferase_complex,_transferring_phosphorus-containing_groups


id: GO:0062014
description: Negative regulation of small molecule metabolic process
memo: https://amigo.geneontology.org/amigo/term/GO:0062014
golevel: 5
name:
  GOBP.STRING_v12.0_525309_STRINGid_GO:0062014_Negative_regulation_of_small_molecule_metabolic_process


id: GO:0070204
description: 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase activity
memo: https://amigo.geneontology.org/amigo/term/GO:0070204
golevel: 4
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0070204_2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid_synthase_activity


id: GO:0070205
description: 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase activity
memo: https://amigo.geneontology.org/amigo/term/GO:0070205
golevel: 4
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0070205_2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate_synthase_activity


id: GO:0070626
memo: https://amigo.geneontology.org/amigo/term/GO:0070626
golevel: 5
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0070626_(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)_succinate_lyase_(fumarate-forming)_activity

description:
  (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity


id: GO:0070647
description: Protein modification by small protein conjugation or removal
memo: https://amigo.geneontology.org/amigo/term/GO:0070647
golevel: 6
name:
  GOBP.STRING_v12.0_525309_STRINGid_GO:0070647_Protein_modification_by_small_protein_conjugation_or_removal


id: GO:0071951
description: Conversion of methionyl-tRNA to N-formyl-methionyl-tRNA
memo: https://amigo.geneontology.org/amigo/term/GO:0071951
golevel: 12
name:
  GOBP.STRING_v12.0_525309_STRINGid_GO:0071951_Conversion_of_methionyl-tRNA_to_N-formyl-methionyl-tRNA


id: GO:0072599
description: Establishment of protein localization to endoplasmic reticulum
memo: https://amigo.geneontology.org/amigo/term/GO:0072599
golevel: 7
name:
  GOBP.STRING_v12.0_525309_STRINGid_GO:0072599_Establishment_of_protein_localization_to_endoplasmic_reticulum


id: GO:0097588
description: Archaeal or bacterial-type flagellum-dependent cell motility
memo: https://amigo.geneontology.org/amigo/term/GO:0097588
golevel: 4
name:
  GOBP.STRING_v12.0_525309_STRINGid_GO:0097588_Archaeal_or_bacterial-type_flagellum-dependent_cell_motility


id: GO:0102027
description: S-adenosylmethionine:2-demethylquinol-8 methyltransferase activity
memo: https://amigo.geneontology.org/amigo/term/GO:0102027
golevel: 5
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0102027_S-adenosylmethionine:2-demethylquinol-8_methyltransferase_activity


id: GO:0102094
description: S-adenosylmethionine:2-demethylmenaquinol methyltransferase activity
memo: https://amigo.geneontology.org/amigo/term/GO:0102094
golevel: 5
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0102094_S-adenosylmethionine:2-demethylmenaquinol_methyltransferase_activity


id: GO:0102955
description: S-adenosylmethionine:2-demethylmenaquinol-7 methyltransferase activity
memo: https://amigo.geneontology.org/amigo/term/GO:0102955
golevel: 5
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0102955_S-adenosylmethionine:2-demethylmenaquinol-7_methyltransferase_activity


id: GO:0106074
description: aminoacyl-tRNA metabolism involved in translational fidelity
memo: https://amigo.geneontology.org/amigo/term/GO:0106074
golevel: 9
name:
  GOBP.STRING_v12.0_525309_STRINGid_GO:0106074_aminoacyl-tRNA_metabolism_involved_in_translational_fidelity


id: GO:0140078
description: Class I DNA-(apurinic or apyrimidinic site) endonuclease activity
memo: https://amigo.geneontology.org/amigo/term/GO:0140078
golevel: 5
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:0140078_Class_I_DNA-(apurinic_or_apyrimidinic_site)_endonuclease_activity


id: GO:1900192
description: Positive regulation of single-species biofilm formation
memo: https://amigo.geneontology.org/amigo/term/GO:1900192
golevel: 7
name:
  GOBP.STRING_v12.0_525309_STRINGid_GO:1900192_Positive_regulation_of_single-species_biofilm_formation


id: GO:1900231
description: Regulation of single-species biofilm formation on inanimate substrate
memo: https://amigo.geneontology.org/amigo/term/GO:1900231
golevel: 8
name:
  GOBP.STRING_v12.0_525309_STRINGid_GO:1900231_Regulation_of_single-species_biofilm_formation_on_inanimate_substrate


id: GO:1901381
description: Positive regulation of potassium ion transmembrane transport
memo: https://amigo.geneontology.org/amigo/term/GO:1901381
golevel: 10
name:
  GOBP.STRING_v12.0_525309_STRINGid_GO:1901381_Positive_regulation_of_potassium_ion_transmembrane_transport


id: GO:1901505
description: Carbohydrate derivative transmembrane transporter activity
memo: https://amigo.geneontology.org/amigo/term/GO:1901505
golevel: 3
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:1901505_Carbohydrate_derivative_transmembrane_transporter_activity


id: GO:1901618
description: Organic hydroxy compound transmembrane transporter activity
memo: https://amigo.geneontology.org/amigo/term/GO:1901618
golevel: 3
name:
  GOMF.STRING_v12.0_525309_STRINGid_GO:1901618_Organic_hydroxy_compound_transmembrane_transporter_activity


id: GO:1902011
description: Poly(ribitol phosphate) teichoic acid metabolic process
memo: https://amigo.geneontology.org/amigo/term/GO:1902011
golevel: 5
name:
  GOBP.STRING_v12.0_525309_STRINGid_GO:1902011_Poly(ribitol_phosphate)_teichoic_acid_metabolic_process


id: GO:1902012
description: Poly(ribitol phosphate) teichoic acid biosynthetic process
memo: https://amigo.geneontology.org/amigo/term/GO:1902012
golevel: 9
name:
  GOBP.STRING_v12.0_525309_STRINGid_GO:1902012_Poly(ribitol_phosphate)_teichoic_acid_biosynthetic_process


id: GO:1903507
description: Negative regulation of nucleic acid-templated transcription
memo: https://amigo.geneontology.org/amigo/term/GO:1903507
name:
  GOBP.STRING_v12.0_525309_STRINGid_GO:1903507_Negative_regulation_of_nucleic_acid-templated_transcription


id: GO:1903508
description: Positive regulation of nucleic acid-templated transcription
memo: https://amigo.geneontology.org/amigo/term/GO:1903508
name:
  GOBP.STRING_v12.0_525309_STRINGid_GO:1903508_Positive_regulation_of_nucleic_acid-templated_transcription


id: GO:2000112
description: Regulation of cellular macromolecule biosynthetic process
memo: https://amigo.geneontology.org/amigo/term/GO:2000112
name:
  GOBP.STRING_v12.0_525309_STRINGid_GO:2000112_Regulation_of_cellular_macromolecule_biosynthetic_process


id: GO:2000113
description: Negative regulation of cellular macromolecule biosynthetic process
memo: https://amigo.geneontology.org/amigo/term/GO:2000113
name:
  GOBP.STRING_v12.0_525309_STRINGid_GO:2000113_Negative_regulation_of_cellular_macromolecule_biosynthetic_process


id: GOCC:0000015
description: Phosphopyruvate hydratase complex
memo: https://amigo.geneontology.org/amigo/term/GO:0000015
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0000015_Phosphopyruvate_hydratase_complex


id: GOCC:0000118
description: Histone deacetylase complex
memo: https://amigo.geneontology.org/amigo/term/GO:0000118
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0000118_Histone_deacetylase_complex


id: GOCC:0000159
description: Protein phosphatase type 2A complex
memo: https://amigo.geneontology.org/amigo/term/GO:0000159
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0000159_Protein_phosphatase_type_2A_complex


id: GOCC:0000228
description: Nuclear chromosome
memo: https://amigo.geneontology.org/amigo/term/GO:0000228
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0000228_Nuclear_chromosome


id: GOCC:0000324
description: Fungal-type vacuole
memo: https://amigo.geneontology.org/amigo/term/GO:0000324
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0000324_Fungal-type_vacuole


id: GOCC:0000329
description: Fungal-type vacuole membrane
memo: https://amigo.geneontology.org/amigo/term/GO:0000329
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0000329_Fungal-type_vacuole_membrane


id: GOCC:0000428
description: DNA-directed RNA polymerase complex
memo: https://amigo.geneontology.org/amigo/term/GO:0000428
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0000428_DNA-directed_RNA_polymerase_complex


id: GOCC:0000502
description: Proteasome complex
memo: https://amigo.geneontology.org/amigo/term/GO:0000502
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0000502_Proteasome_complex


id: GOCC:0000775
description: Chromosome, centromeric region
memo: https://amigo.geneontology.org/amigo/term/GO:0000775
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0000775_Chromosome,_centromeric_region


id: GOCC:0000779
description: Condensed chromosome, centromeric region
memo: https://amigo.geneontology.org/amigo/term/GO:0000779
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0000779_Condensed_chromosome,_centromeric_region


id: GOCC:0000781
description: Chromosome, telomeric region
memo: https://amigo.geneontology.org/amigo/term/GO:0000781
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0000781_Chromosome,_telomeric_region


id: GOCC:0000793
description: Condensed chromosome
memo: https://amigo.geneontology.org/amigo/term/GO:0000793
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0000793_Condensed_chromosome


id: GOCC:0000930
description: Gamma-tubulin complex
memo: https://amigo.geneontology.org/amigo/term/GO:0000930
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0000930_Gamma-tubulin_complex


id: GOCC:0000931
description: Gamma-tubulin large complex
memo: https://amigo.geneontology.org/amigo/term/GO:0000931
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0000931_Gamma-tubulin_large_complex


id: GOCC:0002189
description: Ribose phosphate diphosphokinase complex
memo: https://amigo.geneontology.org/amigo/term/GO:0002189
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0002189_Ribose_phosphate_diphosphokinase_complex


id: GOCC:0005576
description: Extracellular region
memo: https://amigo.geneontology.org/amigo/term/GO:0005576
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0005576_Extracellular_region


id: GOCC:0005615
description: Extracellular space
memo: https://amigo.geneontology.org/amigo/term/GO:0005615
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0005615_Extracellular_space


id: GOCC:0005663
description: DNA replication factor C complex
memo: https://amigo.geneontology.org/amigo/term/GO:0005663
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0005663_DNA_replication_factor_C_complex


id: GOCC:0005727
description: Extrachromosomal circular DNA
memo: https://amigo.geneontology.org/amigo/term/GO:0005727
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0005727_Extrachromosomal_circular_DNA


id: GOCC:0005740
description: Mitochondrial envelope
memo: https://amigo.geneontology.org/amigo/term/GO:0005740
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0005740_Mitochondrial_envelope


id: GOCC:0005743
description: Mitochondrial inner membrane
memo: https://amigo.geneontology.org/amigo/term/GO:0005743
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0005743_Mitochondrial_inner_membrane


id: GOCC:0005746
description: Mitochondrial respirasome
memo: https://amigo.geneontology.org/amigo/term/GO:0005746
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0005746_Mitochondrial_respirasome


id: GOCC:0005747
description: Mitochondrial respiratory chain complex I
memo: https://amigo.geneontology.org/amigo/term/GO:0005747
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0005747_Mitochondrial_respiratory_chain_complex_I


id: GOCC:0005759
description: Mitochondrial matrix
memo: https://amigo.geneontology.org/amigo/term/GO:0005759
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0005759_Mitochondrial_matrix


id: GOCC:0005778
description: Peroxisomal membrane
memo: https://amigo.geneontology.org/amigo/term/GO:0005778
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0005778_Peroxisomal_membrane


id: GOCC:0005783
description: Endoplasmic reticulum
memo: https://amigo.geneontology.org/amigo/term/GO:0005783
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0005783_Endoplasmic_reticulum


id: GOCC:0005788
description: Endoplasmic reticulum lumen
memo: https://amigo.geneontology.org/amigo/term/GO:0005788
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0005788_Endoplasmic_reticulum_lumen


id: GOCC:0005789
description: Endoplasmic reticulum membrane
memo: https://amigo.geneontology.org/amigo/term/GO:0005789
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0005789_Endoplasmic_reticulum_membrane


id: GOCC:0005793
description: Endoplasmic reticulum-Golgi intermediate compartment
memo: https://amigo.geneontology.org/amigo/term/GO:0005793
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0005793_Endoplasmic_reticulum-Golgi_intermediate_compartment


id: GOCC:0005798
description: Golgi-associated vesicle
memo: https://amigo.geneontology.org/amigo/term/GO:0005798
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0005798_Golgi-associated_vesicle


id: GOCC:0005815
description: Microtubule organizing center
memo: https://amigo.geneontology.org/amigo/term/GO:0005815
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0005815_Microtubule_organizing_center


id: GOCC:0005835
description: Fatty acid synthase complex
memo: https://amigo.geneontology.org/amigo/term/GO:0005835
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0005835_Fatty_acid_synthase_complex


id: GOCC:0005885
description: Arp2/3 protein complex
memo: https://amigo.geneontology.org/amigo/term/GO:0005885
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0005885_Arp2/3_protein_complex


id: GOCC:0005887
description: Integral component of plasma membrane
memo: https://amigo.geneontology.org/amigo/term/GO:0005887
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0005887_Integral_component_of_plasma_membrane


id: GOCC:0005911
description: Cell-cell junction
memo: https://amigo.geneontology.org/amigo/term/GO:0005911
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0005911_Cell-cell_junction


id: GOCC:0005948
description: Acetolactate synthase complex
memo: https://amigo.geneontology.org/amigo/term/GO:0005948
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0005948_Acetolactate_synthase_complex


id: GOCC:0005951
description: Carbamoyl-phosphate synthase complex
memo: https://amigo.geneontology.org/amigo/term/GO:0005951
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0005951_Carbamoyl-phosphate_synthase_complex


id: GOCC:0005960
description: Glycine cleavage complex
memo: https://amigo.geneontology.org/amigo/term/GO:0005960
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0005960_Glycine_cleavage_complex


id: GOCC:0005963
description: Magnesium-dependent protein serine/threonine phosphatase complex
memo: https://amigo.geneontology.org/amigo/term/GO:0005963
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0005963_Magnesium-dependent_protein_serine/threonine_phosphatase_complex


id: GOCC:0005971
description: Ribonucleoside-diphosphate reductase complex
memo: https://amigo.geneontology.org/amigo/term/GO:0005971
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0005971_Ribonucleoside-diphosphate_reductase_complex


id: GOCC:0008076
description: Voltage-gated potassium channel complex
memo: https://amigo.geneontology.org/amigo/term/GO:0008076
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0008076_Voltage-gated_potassium_channel_complex


id: GOCC:0008287
description: Protein serine/threonine phosphatase complex
memo: https://amigo.geneontology.org/amigo/term/GO:0008287
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0008287_Protein_serine/threonine_phosphatase_complex


id: GOCC:0009279
description: Cell outer membrane
memo: https://amigo.geneontology.org/amigo/term/GO:0009279
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0009279_Cell_outer_membrane


id: GOCC:0009288
description: Bacterial-type flagellum
memo: https://amigo.geneontology.org/amigo/term/GO:0009288
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0009288_Bacterial-type_flagellum


id: GOCC:0009317
description: acetyl-CoA carboxylase complex
memo: https://amigo.geneontology.org/amigo/term/GO:0009317
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0009317_acetyl-CoA_carboxylase_complex


id: GOCC:0009318
description: Exodeoxyribonuclease VII complex
memo: https://amigo.geneontology.org/amigo/term/GO:0009318
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0009318_Exodeoxyribonuclease_VII_complex


id: GOCC:0009321
description: Alkyl hydroperoxide reductase complex
memo: https://amigo.geneontology.org/amigo/term/GO:0009321
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0009321_Alkyl_hydroperoxide_reductase_complex


id: GOCC:0009326
description: Formate dehydrogenase complex
memo: https://amigo.geneontology.org/amigo/term/GO:0009326
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0009326_Formate_dehydrogenase_complex


id: GOCC:0009328
description: phenylalanine-tRNA ligase complex
memo: https://amigo.geneontology.org/amigo/term/GO:0009328
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0009328_phenylalanine-tRNA_ligase_complex


id: GOCC:0009330
description: DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex
memo: https://amigo.geneontology.org/amigo/term/GO:0009330
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0009330_DNA_topoisomerase_type_II_(double_strand_cut,_ATP-hydrolyzing)_complex


id: GOCC:0009331
description: glycerol-3-phosphate dehydrogenase complex
memo: https://amigo.geneontology.org/amigo/term/GO:0009331
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0009331_glycerol-3-phosphate_dehydrogenase_complex


id: GOCC:0009338
description: Exodeoxyribonuclease V complex
memo: https://amigo.geneontology.org/amigo/term/GO:0009338
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0009338_Exodeoxyribonuclease_V_complex


id: GOCC:0009341
description: Beta-galactosidase complex
memo: https://amigo.geneontology.org/amigo/term/GO:0009341
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0009341_Beta-galactosidase_complex


id: GOCC:0009345
description: glycine-tRNA ligase complex
memo: https://amigo.geneontology.org/amigo/term/GO:0009345
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0009345_glycine-tRNA_ligase_complex


id: GOCC:0009346
description: Citrate lyase complex
memo: https://amigo.geneontology.org/amigo/term/GO:0009346
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0009346_Citrate_lyase_complex


id: GOCC:0009347
description: Aspartate carbamoyltransferase complex
memo: https://amigo.geneontology.org/amigo/term/GO:0009347
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0009347_Aspartate_carbamoyltransferase_complex


id: GOCC:0009349
description: Riboflavin synthase complex
memo: https://amigo.geneontology.org/amigo/term/GO:0009349
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0009349_Riboflavin_synthase_complex


id: GOCC:0009358
description: Polyphosphate kinase complex
memo: https://amigo.geneontology.org/amigo/term/GO:0009358
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0009358_Polyphosphate_kinase_complex


id: GOCC:0009360
description: DNA polymerase III complex
memo: https://amigo.geneontology.org/amigo/term/GO:0009360
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0009360_DNA_polymerase_III_complex


id: GOCC:0009366
description: Enterobactin synthetase complex
memo: https://amigo.geneontology.org/amigo/term/GO:0009366
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0009366_Enterobactin_synthetase_complex


id: GOCC:0009376
description: HslUV protease complex
memo: https://amigo.geneontology.org/amigo/term/GO:0009376
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0009376_HslUV_protease_complex


id: GOCC:0009379
description: Holliday junction helicase complex
memo: https://amigo.geneontology.org/amigo/term/GO:0009379
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0009379_Holliday_junction_helicase_complex


id: GOCC:0009380
description: Excinuclease repair complex
memo: https://amigo.geneontology.org/amigo/term/GO:0009380
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0009380_Excinuclease_repair_complex


id: GOCC:0009505
description: Plant-type cell wall
memo: https://amigo.geneontology.org/amigo/term/GO:0009505
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0009505_Plant-type_cell_wall


id: GOCC:0009538
description: Photosystem I reaction center
memo: https://amigo.geneontology.org/amigo/term/GO:0009538
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0009538_Photosystem_I_reaction_center


id: GOCC:0009570
description: Chloroplast stroma
memo: https://amigo.geneontology.org/amigo/term/GO:0009570
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0009570_Chloroplast_stroma


id: GOCC:0009898
description: Cytoplasmic side of plasma membrane
memo: https://amigo.geneontology.org/amigo/term/GO:0009898
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0009898_Cytoplasmic_side_of_plasma_membrane


id: GOCC:0012505
description: Endomembrane system
memo: https://amigo.geneontology.org/amigo/term/GO:0012505
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0012505_Endomembrane_system


id: GOCC:0012507
description: ER to Golgi transport vesicle membrane
memo: https://amigo.geneontology.org/amigo/term/GO:0012507
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0012507_ER_to_Golgi_transport_vesicle_membrane


id: GOCC:0015627
description: Type II protein secretion system complex
memo: https://amigo.geneontology.org/amigo/term/GO:0015627
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0015627_Type_II_protein_secretion_system_complex


id: GOCC:0015629
description: Actin cytoskeleton
memo: https://amigo.geneontology.org/amigo/term/GO:0015629
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0015629_Actin_cytoskeleton


id: GOCC:0015630
description: Microtubule cytoskeleton
memo: https://amigo.geneontology.org/amigo/term/GO:0015630
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0015630_Microtubule_cytoskeleton


id: GOCC:0015934
description: Large ribosomal subunit
memo: https://amigo.geneontology.org/amigo/term/GO:0015934
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0015934_Large_ribosomal_subunit


id: GOCC:0015935
description: Small ribosomal subunit
memo: https://amigo.geneontology.org/amigo/term/GO:0015935
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0015935_Small_ribosomal_subunit


id: GOCC:0016021
description: Integral component of membrane
memo: https://amigo.geneontology.org/amigo/term/GO:0016021
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0016021_Integral_component_of_membrane


id: GOCC:0016465
description: Chaperonin ATPase complex
memo: https://amigo.geneontology.org/amigo/term/GO:0016465
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0016465_Chaperonin_ATPase_complex


id: GOCC:0016469
description: Proton-transporting two-sector ATPase complex
memo: https://amigo.geneontology.org/amigo/term/GO:0016469
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0016469_Proton-transporting_two-sector_ATPase_complex


id: GOCC:0017101
description: aminoacyl-tRNA synthetase multienzyme complex
memo: https://amigo.geneontology.org/amigo/term/GO:0017101
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0017101_aminoacyl-tRNA_synthetase_multienzyme_complex


id: GOCC:0017122
description: Protein N-acetylglucosaminyltransferase complex
memo: https://amigo.geneontology.org/amigo/term/GO:0017122
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0017122_Protein_N-acetylglucosaminyltransferase_complex


id: GOCC:0018995
description: Host cellular component
memo: https://amigo.geneontology.org/amigo/term/GO:0018995
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0018995_Host_cellular_component


id: GOCC:0019008
description: Molybdopterin synthase complex
memo: https://amigo.geneontology.org/amigo/term/GO:0019008
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0019008_Molybdopterin_synthase_complex


id: GOCC:0019866
description: Organelle inner membrane
memo: https://amigo.geneontology.org/amigo/term/GO:0019866
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0019866_Organelle_inner_membrane


id: GOCC:0019897
description: Extrinsic component of plasma membrane
memo: https://amigo.geneontology.org/amigo/term/GO:0019897
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0019897_Extrinsic_component_of_plasma_membrane


id: GOCC:0019898
description: Extrinsic component of membrane
memo: https://amigo.geneontology.org/amigo/term/GO:0019898
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0019898_Extrinsic_component_of_membrane


id: GOCC:0022625
description: Cytosolic large ribosomal subunit
memo: https://amigo.geneontology.org/amigo/term/GO:0022625
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0022625_Cytosolic_large_ribosomal_subunit


id: GOCC:0022626
description: Cytosolic ribosome
memo: https://amigo.geneontology.org/amigo/term/GO:0022626
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0022626_Cytosolic_ribosome


id: GOCC:0022627
description: Cytosolic small ribosomal subunit
memo: https://amigo.geneontology.org/amigo/term/GO:0022627
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0022627_Cytosolic_small_ribosomal_subunit


id: GOCC:0030075
description: Bacterial thylakoid
memo: https://amigo.geneontology.org/amigo/term/GO:0030075
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0030075_Bacterial_thylakoid


id: GOCC:0030127
description: COPII vesicle coat
memo: https://amigo.geneontology.org/amigo/term/GO:0030127
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0030127_COPII_vesicle_coat


id: GOCC:0030134
description: COPII-coated ER to Golgi transport vesicle
memo: https://amigo.geneontology.org/amigo/term/GO:0030134
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0030134_COPII-coated_ER_to_Golgi_transport_vesicle


id: GOCC:0030288
description: Outer membrane-bounded periplasmic space
memo: https://amigo.geneontology.org/amigo/term/GO:0030288
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0030288_Outer_membrane-bounded_periplasmic_space


id: GOCC:0030312
description: External encapsulating structure
memo: https://amigo.geneontology.org/amigo/term/GO:0030312
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0030312_External_encapsulating_structure


id: GOCC:0030658
description: Transport vesicle membrane
memo: https://amigo.geneontology.org/amigo/term/GO:0030658
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0030658_Transport_vesicle_membrane


id: GOCC:0030659
description: Cytoplasmic vesicle membrane
memo: https://amigo.geneontology.org/amigo/term/GO:0030659
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0030659_Cytoplasmic_vesicle_membrane


id: GOCC:0030660
description: Golgi-associated vesicle membrane
memo: https://amigo.geneontology.org/amigo/term/GO:0030660
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0030660_Golgi-associated_vesicle_membrane


id: GOCC:0030662
description: Coated vesicle membrane
memo: https://amigo.geneontology.org/amigo/term/GO:0030662
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0030662_Coated_vesicle_membrane


id: GOCC:0030677
description: Ribonuclease P complex
memo: https://amigo.geneontology.org/amigo/term/GO:0030677
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0030677_Ribonuclease_P_complex


id: GOCC:0030880
description: RNA polymerase complex
memo: https://amigo.geneontology.org/amigo/term/GO:0030880
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0030880_RNA_polymerase_complex


id: GOCC:0030956
description: glutamyl-tRNA(Gln) amidotransferase complex
memo: https://amigo.geneontology.org/amigo/term/GO:0030956
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0030956_glutamyl-tRNA(Gln)_amidotransferase_complex


id: GOCC:0030964
description: NADH dehydrogenase complex
memo: https://amigo.geneontology.org/amigo/term/GO:0030964
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0030964_NADH_dehydrogenase_complex


id: GOCC:0031012
description: Extracellular matrix
memo: https://amigo.geneontology.org/amigo/term/GO:0031012
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0031012_Extracellular_matrix


id: GOCC:0031090
description: Organelle membrane
memo: https://amigo.geneontology.org/amigo/term/GO:0031090
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0031090_Organelle_membrane


id: GOCC:0031224
description: Intrinsic component of membrane
memo: https://amigo.geneontology.org/amigo/term/GO:0031224
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0031224_Intrinsic_component_of_membrane


id: GOCC:0031225
description: Anchored component of membrane
memo: https://amigo.geneontology.org/amigo/term/GO:0031225
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0031225_Anchored_component_of_membrane


id: GOCC:0031226
description: Intrinsic component of plasma membrane
memo: https://amigo.geneontology.org/amigo/term/GO:0031226
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0031226_Intrinsic_component_of_plasma_membrane


id: GOCC:0031250
description: Anaerobic ribonucleoside-triphosphate reductase complex
memo: https://amigo.geneontology.org/amigo/term/GO:0031250
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0031250_Anaerobic_ribonucleoside-triphosphate_reductase_complex


id: GOCC:0031410
description: Cytoplasmic vesicle
memo: https://amigo.geneontology.org/amigo/term/GO:0031410
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0031410_Cytoplasmic_vesicle


id: GOCC:0031469
description: Polyhedral organelle
memo: https://amigo.geneontology.org/amigo/term/GO:0031469
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0031469_Polyhedral_organelle


id: GOCC:0031515
description: tRNA (m1A) methyltransferase complex
memo: https://amigo.geneontology.org/amigo/term/GO:0031515
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0031515_tRNA_(m1A)_methyltransferase_complex


id: GOCC:0031522
description: Cell envelope Sec protein transport complex
memo: https://amigo.geneontology.org/amigo/term/GO:0031522
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0031522_Cell_envelope_Sec_protein_transport_complex


id: GOCC:0031597
description: Cytosolic proteasome complex
memo: https://amigo.geneontology.org/amigo/term/GO:0031597
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0031597_Cytosolic_proteasome_complex


id: GOCC:0031903
description: Microbody membrane
memo: https://amigo.geneontology.org/amigo/term/GO:0031903
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0031903_Microbody_membrane


id: GOCC:0031966
description: Mitochondrial membrane
memo: https://amigo.geneontology.org/amigo/term/GO:0031966
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0031966_Mitochondrial_membrane


id: GOCC:0031967
description: Organelle envelope
memo: https://amigo.geneontology.org/amigo/term/GO:0031967
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0031967_Organelle_envelope


id: GOCC:0031974
description: Membrane-enclosed lumen
memo: https://amigo.geneontology.org/amigo/term/GO:0031974
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0031974_Membrane-enclosed_lumen


id: GOCC:0031984
description: Organelle subcompartment
memo: https://amigo.geneontology.org/amigo/term/GO:0031984
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0031984_Organelle_subcompartment


id: GOCC:0032153
description: Cell division site
memo: https://amigo.geneontology.org/amigo/term/GO:0032153
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0032153_Cell_division_site


id: GOCC:0032156
description: Septin cytoskeleton
memo: https://amigo.geneontology.org/amigo/term/GO:0032156
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0032156_Septin_cytoskeleton


id: GOCC:0032299
description: Ribonuclease H2 complex
memo: https://amigo.geneontology.org/amigo/term/GO:0032299
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0032299_Ribonuclease_H2_complex


id: GOCC:0032300
description: Mismatch repair complex
memo: https://amigo.geneontology.org/amigo/term/GO:0032300
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0032300_Mismatch_repair_complex


id: GOCC:0032991
description: Protein-containing complex
memo: https://amigo.geneontology.org/amigo/term/GO:0032991
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0032991_Protein-containing_complex


id: GOCC:0032993
description: protein-DNA complex
memo: https://amigo.geneontology.org/amigo/term/GO:0032993
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0032993_protein-DNA_complex


id: GOCC:0033176
description: Proton-transporting V-type ATPase complex
memo: https://amigo.geneontology.org/amigo/term/GO:0033176
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0033176_Proton-transporting_V-type_ATPase_complex


id: GOCC:0033177
description: Proton-transporting two-sector ATPase complex, proton-transporting domain
memo: https://amigo.geneontology.org/amigo/term/GO:0033177
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0033177_Proton-transporting_two-sector_ATPase_complex,_proton-transporting_domain


id: GOCC:0033178
description: Proton-transporting two-sector ATPase complex, catalytic domain
memo: https://amigo.geneontology.org/amigo/term/GO:0033178
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0033178_Proton-transporting_two-sector_ATPase_complex,_catalytic_domain


id: GOCC:0033179
description: Proton-transporting V-type ATPase, V0 domain
memo: https://amigo.geneontology.org/amigo/term/GO:0033179
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0033179_Proton-transporting_V-type_ATPase,_V0_domain


id: GOCC:0033202
description: DNA helicase complex
memo: https://amigo.geneontology.org/amigo/term/GO:0033202
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0033202_DNA_helicase_complex


id: GOCC:0034357
description: Photosynthetic membrane
memo: https://amigo.geneontology.org/amigo/term/GO:0034357
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0034357_Photosynthetic_membrane


id: GOCC:0034702
description: Ion channel complex
memo: https://amigo.geneontology.org/amigo/term/GO:0034702
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0034702_Ion_channel_complex


id: GOCC:0034703
description: Cation channel complex
memo: https://amigo.geneontology.org/amigo/term/GO:0034703
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0034703_Cation_channel_complex


id: GOCC:0034705
description: Potassium channel complex
memo: https://amigo.geneontology.org/amigo/term/GO:0034705
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0034705_Potassium_channel_complex


id: GOCC:0034707
description: Chloride channel complex
memo: https://amigo.geneontology.org/amigo/term/GO:0034707
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0034707_Chloride_channel_complex


id: GOCC:0034708
description: Methyltransferase complex
memo: https://amigo.geneontology.org/amigo/term/GO:0034708
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0034708_Methyltransferase_complex


id: GOCC:0035770
description: Ribonucleoprotein granule
memo: https://amigo.geneontology.org/amigo/term/GO:0035770
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0035770_Ribonucleoprotein_granule


id: GOCC:0035861
description: Site of double-strand break
memo: https://amigo.geneontology.org/amigo/term/GO:0035861
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0035861_Site_of_double-strand_break


id: GOCC:0036464
description: Cytoplasmic ribonucleoprotein granule
memo: https://amigo.geneontology.org/amigo/term/GO:0036464
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0036464_Cytoplasmic_ribonucleoprotein_granule


id: GOCC:0036477
description: Somatodendritic compartment
memo: https://amigo.geneontology.org/amigo/term/GO:0036477
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0036477_Somatodendritic_compartment


id: GOCC:0042175
description: Nuclear outer membrane-endoplasmic reticulum membrane network
memo: https://amigo.geneontology.org/amigo/term/GO:0042175
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0042175_Nuclear_outer_membrane-endoplasmic_reticulum_membrane_network


id: GOCC:0042575
description: DNA polymerase complex
memo: https://amigo.geneontology.org/amigo/term/GO:0042575
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0042575_DNA_polymerase_complex


id: GOCC:0043025
description: Neuronal cell body
memo: https://amigo.geneontology.org/amigo/term/GO:0043025
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0043025_Neuronal_cell_body


id: GOCC:0043190
description: ATP-binding cassette (ABC) transporter complex
memo: https://amigo.geneontology.org/amigo/term/GO:0043190
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0043190_ATP-binding_cassette_(ABC)_transporter_complex


id: GOCC:0043227
description: Membrane-bounded organelle
memo: https://amigo.geneontology.org/amigo/term/GO:0043227
name:
  Subcellular localization (COMPARTMENTS).STRING_v12.0_525309_STRINGid_GOCC:0043227_Membrane-bounded_organelle


