# geneInfo

ensembl_gene_id: HMPREF0299_5003
symbol: trxA
gene_biotype: protein_coding
description:
  Thioredoxin; Identified by match to protein family HMM PF00085; match to protein family HMM TIGR01068; Belongs to the thioredoxin family.


ensembl_gene_id: HMPREF0299_5005
symbol: EFM48239.1
gene_biotype: protein_coding
description:
  Copper-exporting ATPase; Identified by match to protein family HMM PF00122; match to protein family HMM PF00403; match to protein family HMM PF00702; match to protein family HMM TIGR01494; match to protein family HMM TIGR01511; match to protein family HMM TIGR01525.


ensembl_gene_id: HMPREF0299_5015
symbol: dnaB
gene_biotype: protein_coding
description:
  Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily.


ensembl_gene_id: HMPREF0299_5024
symbol: EFM48356.1
gene_biotype: protein_coding
description:
  Transcriptional regulator, LuxR family; Identified by match to protein family HMM PF00072; match to protein family HMM PF00196.


ensembl_gene_id: HMPREF0299_5029
symbol: EFM48364.1
gene_biotype: protein_coding
description:
  Transglycosylase; Identified by match to protein family HMM PF00905; match to protein family HMM PF00912.


ensembl_gene_id: HMPREF0299_5030
symbol: EFM48330.1
gene_biotype: protein_coding
description:
  Transcriptional regulator, MarR family; Identified by match to protein family HMM PF01047; match to protein family HMM PF03551.


ensembl_gene_id: HMPREF0299_5031
symbol: EFM48285.1
gene_biotype: protein_coding
description:
  Oxidoreductase, short chain dehydrogenase/reductase family protein; Identified by match to protein family HMM PF00106; match to protein family HMM PF01370.


ensembl_gene_id: HMPREF0299_5040
symbol: EFM48393.1
gene_biotype: protein_coding
description:
  Formamidopyrimidine-DNA glycosylase H2TH domain protein; Identified by match to protein family HMM PF06831; Belongs to the FPG family.


ensembl_gene_id: HMPREF0299_5044
symbol: nnrD
gene_biotype: protein_coding
description:
  Putative YjeF domain protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.  Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of  [...]


ensembl_gene_id: HMPREF0299_5052
symbol: EFM48357.1
gene_biotype: protein_coding
description:
  Putative glutamyl endopeptidase; Identified by match to protein family HMM PF00089; Belongs to the peptidase S1B family.


ensembl_gene_id: HMPREF0299_5058
symbol: bglH
gene_biotype: protein_coding
description:
  Glycosyl hydrolase, family 1; Identified by match to protein family HMM PF00232; Belongs to the glycosyl hydrolase 1 family.


ensembl_gene_id: HMPREF0299_5060
symbol: leuS
gene_biotype: protein_coding
description:
  leucine--tRNA ligase; Identified by match to protein family HMM PF08264; match to protein family HMM PF09334; match to protein family HMM TIGR00396; Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: HMPREF0299_5068
symbol: EFM48335.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein TIGR02185; Identified by match to protein family HMM PF09605; match to protein family HMM TIGR02185.


ensembl_gene_id: HMPREF0299_5072
symbol: EFM48329.1
gene_biotype: protein_coding
description:
  DNA-binding helix-turn-helix protein; Identified by match to protein family HMM PF01381; match to protein family HMM PF07022.


ensembl_gene_id: HMPREF0299_5074
symbol: EFM48363.1
gene_biotype: protein_coding
description:
  Transporter, dicarboxylate/amino acid:cation Na+/H+ symporter family protein; Identified by match to protein family HMM PF00375; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: HMPREF0299_5076
symbol: trpB
gene_biotype: protein_coding
description:
  Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.


ensembl_gene_id: HMPREF0299_5077
symbol: trpE
gene_biotype: protein_coding
description:
  Anthranilate synthase component I; Identified by match to protein family HMM PF00425; match to protein family HMM PF04715; match to protein family HMM TIGR00565.


ensembl_gene_id: HMPREF0299_5079
symbol: trpD
gene_biotype: protein_coding
description:
  Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).


ensembl_gene_id: HMPREF0299_5080
symbol: trpC
gene_biotype: protein_coding
description:
  Indole-3-glycerol phosphate synthase; Identified by match to protein family HMM PF00218; match to protein family HMM PF00697; Belongs to the TrpF family.


ensembl_gene_id: HMPREF0299_5082
symbol: trpA
gene_biotype: protein_coding
description:
  Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.


ensembl_gene_id: HMPREF0299_5093
symbol: EFM48209.1
gene_biotype: protein_coding
description:
  Putative ACR, COG1678; Identified by match to protein family HMM PF02622; Belongs to the UPF0301 (AlgH) family.


ensembl_gene_id: HMPREF0299_5094
symbol: EFM48308.1
gene_biotype: protein_coding
description:
  tRNA adenylyltransferase; Identified by match to protein family HMM PF01743; match to protein family HMM PF01966; match to protein family HMM TIGR00277; match to protein family HMM TIGR02692; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.


ensembl_gene_id: HMPREF0299_5095
symbol: EFM48210.1
gene_biotype: protein_coding
description:
  Hydrolase, NUDIX family; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by match to protein family HMM PF00293; Belongs to the Nudix hydrolase family.


ensembl_gene_id: HMPREF0299_5099
symbol: EFM48324.1
gene_biotype: protein_coding
description:
  Sigma-70 region 2; Identified by match to protein family HMM PF04542; match to protein family HMM PF08281; match to protein family HMM TIGR02937; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: HMPREF0299_5100
symbol: trxB
gene_biotype: protein_coding
description:
  Thioredoxin-disulfide reductase; Identified by match to protein family HMM PF00070; match to protein family HMM PF01266; match to protein family HMM PF07992; match to protein family HMM TIGR01292.


ensembl_gene_id: HMPREF0299_5102
symbol: EFM48349.1
gene_biotype: protein_coding
description:
  N-acetylmuramoyl-L-alanine amidase; Identified by match to protein family HMM PF01471; match to protein family HMM PF01520.


ensembl_gene_id: HMPREF0299_5105
symbol: EFM48288.1
gene_biotype: protein_coding
description:
  Identified by match to protein family HMM PF02195; match to protein family HMM TIGR00180; Belongs to the ParB family.


ensembl_gene_id: HMPREF0299_5106
symbol: soj
gene_biotype: protein_coding
description:
  CobQ/CobB/MinD/ParA nucleotide binding domain protein; Identified by match to protein family HMM PF01656.


ensembl_gene_id: HMPREF0299_5107
symbol: gidB
gene_biotype: protein_coding
description:
  16S rRNA methyltransferase GidB; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.


ensembl_gene_id: HMPREF0299_5108
symbol: EFM48247.1
gene_biotype: protein_coding
description:
  Membrane protein insertase, YidC/Oxa1 family; Identified by match to protein family HMM PF02096; match to protein family HMM TIGR03592.


ensembl_gene_id: HMPREF0299_5109
symbol: EFM48341.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein YidD; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family.


ensembl_gene_id: HMPREF0299_5110
symbol: rnpA
gene_biotype: protein_coding
description:
  Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.


ensembl_gene_id: HMPREF0299_5111
symbol: rpmH
gene_biotype: protein_coding
description:
  Ribosomal protein L34; Identified by match to protein family HMM PF00468; match to protein family HMM TIGR01030; Belongs to the bacterial ribosomal protein bL34 family.


ensembl_gene_id: HMPREF0299_5113
symbol: dnaA
gene_biotype: protein_coding
description:
  Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.


ensembl_gene_id: HMPREF0299_5118
symbol: dnaN
gene_biotype: protein_coding
description:
  DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]


ensembl_gene_id: HMPREF0299_5119
symbol: recF
gene_biotype: protein_coding
description:
  DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family.


ensembl_gene_id: HMPREF0299_5121
symbol: gyrB
gene_biotype: protein_coding
description:
  DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.


ensembl_gene_id: HMPREF0299_5124
symbol: EFM48366.1
gene_biotype: protein_coding
description:
  Putative extracellular metalloprotease; Identified by match to protein family HMM PF00089; Belongs to the peptidase S1B family.


ensembl_gene_id: HMPREF0299_5125
symbol: EFM48273.1
gene_biotype: protein_coding
description:
  Hypothetical protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop.


ensembl_gene_id: HMPREF0299_5135
symbol: gyrA
gene_biotype: protein_coding
description:
  DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.


ensembl_gene_id: HMPREF0299_5149
symbol: pdxS
gene_biotype: protein_coding
description:
  Pyridoxal 5'-phosphate synthase, synthase subunit Pdx1; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family.


ensembl_gene_id: HMPREF0299_5151
symbol: EFM48390.1
gene_biotype: protein_coding
description:
  Branched-chain amino acid ABC transporter, permease protein; Identified by match to protein family HMM PF02653; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: HMPREF0299_5154
symbol: cypB
gene_biotype: protein_coding
description:
  Peptidyl-prolyl cis-trans isomerase, cyclophilin-type; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.


ensembl_gene_id: HMPREF0299_5159
symbol: EFM48260.1
gene_biotype: protein_coding
description:
  PASTA domain protein; Identified by match to protein family HMM PF00069; match to protein family HMM PF03793.


ensembl_gene_id: HMPREF0299_5161
symbol: EFM48338.1
gene_biotype: protein_coding
description:
  Penicillin-binding protein, transpeptidase domain protein; Identified by match to protein family HMM PF00905.


ensembl_gene_id: HMPREF0299_5162
symbol: EFM48361.1
gene_biotype: protein_coding
description:
  Cell cycle protein, FtsW/RodA/SpoVE family; Identified by match to protein family HMM PF01098; Belongs to the SEDS family.


ensembl_gene_id: HMPREF0299_5163
symbol: EFM48319.1
gene_biotype: protein_coding
description:
  Stage II sporulation protein E; Identified by match to protein family HMM PF00481; match to protein family HMM PF07228.


ensembl_gene_id: HMPREF0299_5171
symbol: EFM48327.1
gene_biotype: protein_coding
description:
  Transporter, major facilitator family protein; Identified by match to protein family HMM PF00083; match to protein family HMM PF07690.


ensembl_gene_id: HMPREF0299_5172
symbol: EFM48283.1
gene_biotype: protein_coding
description:
  Peptidase dimerization domain protein; Identified by match to protein family HMM PF01546; match to protein family HMM PF07687.


ensembl_gene_id: HMPREF0299_5173
symbol: bioB
gene_biotype: protein_coding
description:
  Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.


ensembl_gene_id: HMPREF0299_5176
symbol: metN
gene_biotype: protein_coding
description:
  ABC transporter, ATP-binding protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.


ensembl_gene_id: HMPREF0299_5180
symbol: EFM48305.1
gene_biotype: protein_coding
description:
  Bacterial surface protein 26-residue PARCEL repeat (3 repeats); Identified by match to protein family HMM PF03382; match to protein family HMM TIGR02167.


ensembl_gene_id: HMPREF0299_5184
symbol: amn
gene_biotype: protein_coding
description:
  AMP nucleosidase; Identified by match to protein family HMM PF01048; match to protein family HMM TIGR01717.


ensembl_gene_id: HMPREF0299_5188
symbol: EFM48286.1
gene_biotype: protein_coding
description:
  Oxidoreductase, short chain dehydrogenase/reductase family protein; Identified by match to protein family HMM PF00106; match to protein family HMM PF08659.


ensembl_gene_id: HMPREF0299_5189
symbol: EFM48395.1
gene_biotype: protein_coding
description:
  Alkylhydroperoxidase AhpD family core domain protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.


ensembl_gene_id: HMPREF0299_5193
symbol: tyrS
gene_biotype: protein_coding
description:
  tyrosine--tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.


ensembl_gene_id: HMPREF0299_5195
symbol: argH
gene_biotype: protein_coding
description:
  Argininosuccinate lyase; Identified by match to protein family HMM PF00206; match to protein family HMM TIGR00838.


ensembl_gene_id: HMPREF0299_5196
symbol: argG
gene_biotype: protein_coding
description:
  Argininosuccinate synthase; Identified by match to protein family HMM PF00764; match to protein family HMM TIGR00032; Belongs to the argininosuccinate synthase family. Type 1 subfamily.


ensembl_gene_id: HMPREF0299_5198
symbol: argF
gene_biotype: protein_coding
description:
  Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.


ensembl_gene_id: HMPREF0299_5199
symbol: argD
gene_biotype: protein_coding
description:
  Aminotransferase, acetylornithine/succinylornithine family; Identified by match to protein family HMM PF00202; match to protein family HMM TIGR00707; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.


ensembl_gene_id: HMPREF0299_5200
symbol: argB
gene_biotype: protein_coding
description:
  Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.


ensembl_gene_id: HMPREF0299_5201
symbol: argJ
gene_biotype: protein_coding
description:
  Glutamate N-acetyltransferase/amino-acid acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.


ensembl_gene_id: HMPREF0299_5202
symbol: argC
gene_biotype: protein_coding
description:
  N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.


ensembl_gene_id: HMPREF0299_5203
symbol: pheT
gene_biotype: protein_coding
description:
  phenylalanine--tRNA ligase, beta subunit; Identified by match to protein family HMM PF01588; match to protein family HMM PF03147; match to protein family HMM PF03483; match to protein family HMM PF03484; match to protein family HMM TIGR00472; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.


ensembl_gene_id: HMPREF0299_5204
symbol: pheS
gene_biotype: protein_coding
description:
  phenylalanine--tRNA ligase, alpha subunit; Identified by match to protein family HMM PF01409; match to protein family HMM PF02912; match to protein family HMM TIGR00468; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.


ensembl_gene_id: HMPREF0299_5206
symbol: EFM47807.1
gene_biotype: protein_coding
description:
  RNA methyltransferase, TrmH family; Identified by match to protein family HMM PF00588; match to protein family HMM PF08032; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.


ensembl_gene_id: HMPREF0299_5207
symbol: rplT
gene_biotype: protein_coding
description:
  Ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.


ensembl_gene_id: HMPREF0299_5208
symbol: rpmI
gene_biotype: protein_coding
description:
  Ribosomal protein L35; Identified by match to protein family HMM PF01632; match to protein family HMM TIGR00001; Belongs to the bacterial ribosomal protein bL35 family.


ensembl_gene_id: HMPREF0299_5209
symbol: infC
gene_biotype: protein_coding
description:
  Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.


ensembl_gene_id: HMPREF0299_5211
symbol: uvrA
gene_biotype: protein_coding
description:
  Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.


ensembl_gene_id: HMPREF0299_5216
symbol: uvrB
gene_biotype: protein_coding
description:
  Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]


ensembl_gene_id: HMPREF0299_5217
symbol: EFM47755.1
gene_biotype: protein_coding
description:
  Hypothetical protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF0299_5218
symbol: coaE
gene_biotype: protein_coding
description:
  dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.


ensembl_gene_id: HMPREF0299_5219
symbol: EFM48101.1
gene_biotype: protein_coding
description:
  Phosphotransferase system, EIIC; Identified by match to protein family HMM PF00358; match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00830.


ensembl_gene_id: HMPREF0299_5220
symbol: EFM48067.1
gene_biotype: protein_coding
description:
  TrkA C-terminal domain protein; Identified by match to protein family HMM PF02080; match to protein family HMM PF06826; match to protein family HMM TIGR01625.


ensembl_gene_id: HMPREF0299_5224
symbol: polA
gene_biotype: protein_coding
description:
  DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.


ensembl_gene_id: HMPREF0299_5234
symbol: coaD
gene_biotype: protein_coding
description:
  Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.


ensembl_gene_id: HMPREF0299_5235
symbol: EFM48185.1
gene_biotype: protein_coding
description:
  RNA methyltransferase, RsmD family; Identified by match to protein family HMM PF03602; match to protein family HMM TIGR00095.


ensembl_gene_id: HMPREF0299_5237
symbol: EFM47952.1
gene_biotype: protein_coding
description:
  Putative ATP-dependent DNA helicase RecG; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF01336.


ensembl_gene_id: HMPREF0299_5239
symbol: ung
gene_biotype: protein_coding
description:
  uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.


ensembl_gene_id: HMPREF0299_5241
symbol: thiL
gene_biotype: protein_coding
description:
  Thiamine-phosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.


ensembl_gene_id: HMPREF0299_5244
symbol: ddl
gene_biotype: protein_coding
description:
  D-ala D-ala ligase N-terminal domain protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.


ensembl_gene_id: HMPREF0299_5245
symbol: gpsA
gene_biotype: protein_coding
description:
  Glycerol-3-phosphate dehydrogenase [NAD(P)+]; Identified by match to protein family HMM PF01210; match to protein family HMM PF02558; match to protein family HMM PF03807; match to protein family HMM PF07479; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.


ensembl_gene_id: HMPREF0299_5246
symbol: EFM47825.1
gene_biotype: protein_coding
description:
  Hydrolase, NUDIX family; Identified by match to protein family HMM PF00293; match to protein family HMM PF00300.


ensembl_gene_id: HMPREF0299_5247
symbol: leuD
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.


ensembl_gene_id: HMPREF0299_5248
symbol: leuC
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.


ensembl_gene_id: HMPREF0299_5249
symbol: EFM47898.1
gene_biotype: protein_coding
description:
  Transcriptional regulator, IclR family, C-terminal domain protein; Identified by match to protein family HMM PF01614; match to protein family HMM PF09339.


ensembl_gene_id: HMPREF0299_5257
symbol: gltX
gene_biotype: protein_coding
description:
  glutamate--tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.


ensembl_gene_id: HMPREF0299_5258
symbol: EFM48204.1
gene_biotype: protein_coding
description:
  Methyltransferase domain protein; Identified by match to protein family HMM PF08241; match to protein family HMM PF08242.


ensembl_gene_id: HMPREF0299_5259
symbol: EFM48056.1
gene_biotype: protein_coding
description:
  TipAS antibiotic-recognition domain protein; Identified by match to protein family HMM PF00376; match to protein family HMM PF07739.


ensembl_gene_id: HMPREF0299_5263
symbol: leuB
gene_biotype: protein_coding
description:
  Putative 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.


ensembl_gene_id: HMPREF0299_5265
symbol: EFM48170.1
gene_biotype: protein_coding
description:
  SufB/sufD domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF01458.


ensembl_gene_id: HMPREF0299_5267
symbol: serA
gene_biotype: protein_coding
description:
  Phosphoglycerate dehydrogenase; Identified by match to protein family HMM PF00389; match to protein family HMM PF01408; match to protein family HMM PF01842; match to protein family HMM PF02826; match to protein family HMM PF03807; match to protein family HMM TIGR01327; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: HMPREF0299_5270
symbol: EFM47890.1
gene_biotype: protein_coding
description:
  Cation diffusion facilitator family transporter; Identified by match to protein family HMM PF01545; match to protein family HMM TIGR01297.


ensembl_gene_id: HMPREF0299_5273
symbol: ilvC
gene_biotype: protein_coding
description:
  Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.


ensembl_gene_id: HMPREF0299_5274
symbol: ilvN
gene_biotype: protein_coding
description:
  Acetolactate synthase, small subunit; Identified by match to protein family HMM PF01842; match to protein family HMM TIGR00119.


ensembl_gene_id: HMPREF0299_5275
symbol: ilvB
gene_biotype: protein_coding
description:
  Acetolactate synthase, large subunit, biosynthetic type; Identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; match to protein family HMM TIGR00118.


ensembl_gene_id: HMPREF0299_5276
symbol: EFM47888.1
gene_biotype: protein_coding
description:
  Transporter, small conductance mechanosensitive ion channel MscS family protein; Identified by match to protein family HMM PF00924.


ensembl_gene_id: HMPREF0299_5278
symbol: ilvD
gene_biotype: protein_coding
description:
  Dihydroxy-acid dehydratase; Identified by match to protein family HMM PF00920; match to protein family HMM TIGR00110; Belongs to the IlvD/Edd family.


ensembl_gene_id: HMPREF0299_5284
symbol: EFM48159.1
gene_biotype: protein_coding
description:
  Chromosome replication initiation inhibitor protein; Identified by match to protein family HMM PF00126; match to protein family HMM TIGR03298; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: HMPREF0299_5286
symbol: gatB
gene_biotype: protein_coding
description:
  aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily.


ensembl_gene_id: HMPREF0299_5287
symbol: EFM48205.1
gene_biotype: protein_coding
description:
  Response regulator receiver domain protein; Identified by match to protein family HMM PF00072; match to protein family HMM PF00196.


ensembl_gene_id: HMPREF0299_5292
symbol: ald
gene_biotype: protein_coding
description:
  Alanine dehydrogenase; Identified by match to protein family HMM PF01262; match to protein family HMM PF05222; match to protein family HMM TIGR00518; Belongs to the AlaDH/PNT family.


ensembl_gene_id: HMPREF0299_5293
symbol: pfkA
gene_biotype: protein_coding
description:
  Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.


ensembl_gene_id: HMPREF0299_5294
symbol: EFM47793.1
gene_biotype: protein_coding
description:
  Drug resistance MFS transporter, drug:H+ antiporter-2 family; Identified by match to protein family HMM PF07690; match to protein family HMM TIGR00711; Belongs to the major facilitator superfamily.


ensembl_gene_id: HMPREF0299_5303
symbol: EFM48147.1
gene_biotype: protein_coding
description:
  Iron chelate uptake ABC transporter, FeCT family, permease protein; Identified by match to protein family HMM PF00950; match to protein family HMM PF01032; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: HMPREF0299_5308
symbol: gatA
gene_biotype: protein_coding
description:
  aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln).


ensembl_gene_id: HMPREF0299_5309
symbol: gatC
gene_biotype: protein_coding
description:
  aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family.


ensembl_gene_id: HMPREF0299_5330
symbol: EFM47948.1
gene_biotype: protein_coding
description:
  ATPase family associated with various cellular activities (AAA); Identified by match to protein family HMM PF07726; match to protein family HMM PF07728.


ensembl_gene_id: HMPREF0299_5334
symbol: EFM47987.1
gene_biotype: protein_coding
description:
  RHS repeat-associated core domain protein; Identified by match to protein family HMM PF05593; match to protein family HMM TIGR01643; match to protein family HMM TIGR03696.


ensembl_gene_id: HMPREF0299_5337
symbol: EFM48068.1
gene_biotype: protein_coding
description:
  Oxidoreductase, aldo/keto reductase family protein; Identified by match to protein family HMM PF00248.


ensembl_gene_id: HMPREF0299_5339
symbol: ligA
gene_biotype: protein_coding
description:
  DNA ligase (NAD+); DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily.


ensembl_gene_id: HMPREF0299_5343
symbol: trmU
gene_biotype: protein_coding
description:
  tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.


ensembl_gene_id: HMPREF0299_5347
symbol: etfA
gene_biotype: protein_coding
description:
  Electron transfer flavoprotein FAD-binding domain protein; Identified by match to protein family HMM PF00766; match to protein family HMM PF01012.


ensembl_gene_id: HMPREF0299_5353
symbol: glgE
gene_biotype: protein_coding
description:
  Alpha amylase, catalytic domain protein; Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.


ensembl_gene_id: HMPREF0299_5354
symbol: glgB
gene_biotype: protein_coding
description:
  1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.


ensembl_gene_id: HMPREF0299_5355
symbol: EFM47992.1
gene_biotype: protein_coding
description:
  ABC transporter, substrate-binding protein, family 5; Identified by match to protein family HMM PF00496.


ensembl_gene_id: HMPREF0299_5358
symbol: mce
gene_biotype: protein_coding
description:
  methylmalonyl-CoA epimerase; Identified by match to protein family HMM PF00903; match to protein family HMM TIGR03081.


ensembl_gene_id: HMPREF0299_5360
symbol: nucS
gene_biotype: protein_coding
description:
  Hypothetical protein; Cleaves both 3' and 5' ssDNA extremities of branched DNA structures; Belongs to the NucS endonuclease family.


ensembl_gene_id: HMPREF0299_5362
symbol: atpC
gene_biotype: protein_coding
description:
  ATP synthase F1, epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane.


ensembl_gene_id: HMPREF0299_5363
symbol: atpD
gene_biotype: protein_coding
description:
  ATP synthase F1, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.


ensembl_gene_id: HMPREF0299_5364
symbol: atpG
gene_biotype: protein_coding
description:
  ATP synthase F1, gamma subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.


ensembl_gene_id: HMPREF0299_5365
symbol: atpA
gene_biotype: protein_coding
description:
  ATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.


ensembl_gene_id: HMPREF0299_5366
symbol: atpH
gene_biotype: protein_coding
description:
  ATP synthase F1, delta subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.


ensembl_gene_id: HMPREF0299_5367
symbol: atpF
gene_biotype: protein_coding
description:
  ATP synthase F0, B subunit; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family.


ensembl_gene_id: HMPREF0299_5368
symbol: atpE
gene_biotype: protein_coding
description:
  ATP synthase F0, C subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.


ensembl_gene_id: HMPREF0299_5369
symbol: atpB
gene_biotype: protein_coding
description:
  ATP synthase F0, A subunit; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family.


ensembl_gene_id: HMPREF0299_5372
symbol: EFM47778.1
gene_biotype: protein_coding
description:
  Identified by match to protein family HMM PF01300; match to protein family HMM TIGR00057; Belongs to the SUA5 family.


ensembl_gene_id: HMPREF0299_5373
symbol: prmC
gene_biotype: protein_coding
description:
  protein-(glutamine-N5) methyltransferase, release factor-specific; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.


ensembl_gene_id: HMPREF0299_5374
symbol: prfA
gene_biotype: protein_coding
description:
  Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.


ensembl_gene_id: HMPREF0299_5375
symbol: rho
gene_biotype: protein_coding
description:
  Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.


ensembl_gene_id: HMPREF0299_5378
symbol: moaA
gene_biotype: protein_coding
description:
  Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.


ensembl_gene_id: HMPREF0299_5379
symbol: EFM47843.1
gene_biotype: protein_coding
description:
  Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.


ensembl_gene_id: HMPREF0299_5380
symbol: moaC
gene_biotype: protein_coding
description:
  Molybdenum cofactor biosynthesis protein C; Identified by match to protein family HMM PF01967; match to protein family HMM TIGR00581.


ensembl_gene_id: HMPREF0299_5381
symbol: EFM48078.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family.


ensembl_gene_id: HMPREF0299_5382
symbol: EFM47880.1
gene_biotype: protein_coding
description:
  Molybdopterin biosynthesis protein MoeB; Identified by match to protein family HMM PF00581; match to protein family HMM PF00899; match to protein family HMM PF05237.


ensembl_gene_id: HMPREF0299_5383
symbol: moaE
gene_biotype: protein_coding
description:
  Molybdopterin converting factor, subunit 2; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF02391.


ensembl_gene_id: HMPREF0299_5388
symbol: EFM48153.1
gene_biotype: protein_coding
description:
  Nitrate reductase, alpha subunit; Identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; match to protein family HMM TIGR01580; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: HMPREF0299_5390
symbol: narJ
gene_biotype: protein_coding
description:
  Nitrate reductase molybdenum cofactor assembly chaperone; Identified by match to protein family HMM PF02613; match to protein family HMM TIGR00684.


ensembl_gene_id: HMPREF0299_5391
symbol: narI
gene_biotype: protein_coding
description:
  Respiratory nitrate reductase, gamma subunit; Identified by match to protein family HMM PF02665; match to protein family HMM TIGR00351.


ensembl_gene_id: HMPREF0299_5392
symbol: modA
gene_biotype: protein_coding
description:
  Molybdate ABC transporter, periplasmic molybdate-binding protein; Identified by match to protein family HMM PF01547; match to protein family HMM TIGR01256.


ensembl_gene_id: HMPREF0299_5393
symbol: modB
gene_biotype: protein_coding
description:
  Molybdate ABC transporter, permease protein; Identified by match to protein family HMM PF00005; match to protein family HMM PF00528; match to protein family HMM PF03459; match to protein family HMM TIGR02141; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: HMPREF0299_5399
symbol: thrB
gene_biotype: protein_coding
description:
  Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.


ensembl_gene_id: HMPREF0299_5400
symbol: EFM47864.1
gene_biotype: protein_coding
description:
  Homoserine dehydrogenase; Identified by match to protein family HMM PF00742; match to protein family HMM PF01842; match to protein family HMM PF03447.


ensembl_gene_id: HMPREF0299_5401
symbol: lysA
gene_biotype: protein_coding
description:
  Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.


ensembl_gene_id: HMPREF0299_5402
symbol: argS
gene_biotype: protein_coding
description:
  arginine--tRNA ligase; Identified by match to protein family HMM PF00750; match to protein family HMM PF03485; match to protein family HMM PF05746; match to protein family HMM TIGR00456.


ensembl_gene_id: HMPREF0299_5403
symbol: EFM47873.1
gene_biotype: protein_coding
description:
  Transporter, lactate permease (LctP) family; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family.


ensembl_gene_id: HMPREF0299_5405
symbol: EFM48137.1
gene_biotype: protein_coding
description:
  Iron-sulfur cluster-binding protein; Identified by match to protein family HMM PF02589; match to protein family HMM TIGR00273.


ensembl_gene_id: HMPREF0299_5410
symbol: EFM47886.1
gene_biotype: protein_coding
description:
  Hypothetical protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain one or more premature stops and/or frameshifts.


ensembl_gene_id: HMPREF0299_5422
symbol: EFM47946.1
gene_biotype: protein_coding
description:
  SNF2 family N-terminal domain protein; Identified by match to protein family HMM PF00176; match to protein family HMM PF00271.


ensembl_gene_id: HMPREF0299_5424
symbol: putP
gene_biotype: protein_coding
description:
  Sodium/proline symporter; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: HMPREF0299_5431
symbol: EFM47877.1
gene_biotype: protein_coding
description:
  ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; Identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518.


ensembl_gene_id: HMPREF0299_5432
symbol: EFM48174.1
gene_biotype: protein_coding
description:
  Response regulator receiver domain protein; Identified by match to protein family HMM PF00072; match to protein family HMM PF00486.


ensembl_gene_id: HMPREF0299_5433
symbol: deaD
gene_biotype: protein_coding
description:
  DEAD/DEAH box helicase; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.


ensembl_gene_id: HMPREF0299_5434
symbol: EFM47892.1
gene_biotype: protein_coding
description:
  Transporter, major facilitator family protein; Identified by match to protein family HMM PF00083; match to protein family HMM PF00293; match to protein family HMM PF07690.


ensembl_gene_id: HMPREF0299_5442
symbol: EFM47819.1
gene_biotype: protein_coding
description:
  Carboxylesterase; Identified by match to protein family HMM PF00135; Belongs to the type-B carboxylesterase/lipase family.


ensembl_gene_id: HMPREF0299_5443
symbol: EFM47869.1
gene_biotype: protein_coding
description:
  Shikimate dehydrogenase; Identified by match to protein family HMM PF01488; match to protein family HMM PF08501.


ensembl_gene_id: HMPREF0299_5445
symbol: EFM48073.1
gene_biotype: protein_coding
description:
  ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005; match to protein family HMM PF00664.


ensembl_gene_id: HMPREF0299_5446
symbol: sucA
gene_biotype: protein_coding
description:
  Oxoglutarate dehydrogenase (succinyl-transferring), E1 component; Identified by match to protein family HMM PF00198; match to protein family HMM PF00676; match to protein family HMM PF02779; match to protein family HMM TIGR00239.


ensembl_gene_id: HMPREF0299_5451
symbol: EFM48038.1
gene_biotype: protein_coding
description:
  MgtE intracellular domain protein; Identified by match to protein family HMM PF00571; match to protein family HMM PF03448.


ensembl_gene_id: HMPREF0299_5453
symbol: EFM48021.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.


ensembl_gene_id: HMPREF0299_5454
symbol: tatB
gene_biotype: protein_coding
description:
  Twin arginine-targeting protein translocase TatB; Identified by match to protein family HMM TIGR01410.


ensembl_gene_id: HMPREF0299_5456
symbol: EFM47815.1
gene_biotype: protein_coding
description:
  RNA polymerase sigma factor SigE; Identified by match to protein family HMM PF04542; match to protein family HMM PF04545; match to protein family HMM PF08281; match to protein family HMM TIGR02937; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: HMPREF0299_5460
symbol: glgC
gene_biotype: protein_coding
description:
  Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.


ensembl_gene_id: HMPREF0299_5461
symbol: glgA
gene_biotype: protein_coding
description:
  Glycogen synthase, Corynebacterium family; Identified by match to protein family HMM PF00534; match to protein family HMM TIGR02149.


ensembl_gene_id: HMPREF0299_5462
symbol: EFM47899.1
gene_biotype: protein_coding
description:
  Glycosyl hydrolase family 32; Identified by match to protein family HMM PF00251; Belongs to the glycosyl hydrolase 32 family.


ensembl_gene_id: HMPREF0299_5463
symbol: EFM47776.1
gene_biotype: protein_coding
description:
  Tat pathway signal sequence domain protein; Identified by match to protein family HMM PF00079; Belongs to the serpin family.


ensembl_gene_id: HMPREF0299_5464
symbol: EFM47818.1
gene_biotype: protein_coding
description:
  Serine proteinase inhibitor; Identified by match to protein family HMM PF00079; Belongs to the serpin family.


ensembl_gene_id: HMPREF0299_5469
symbol: EFM47911.1
gene_biotype: protein_coding
description:
  Identified by match to protein family HMM PF03641; match to protein family HMM TIGR00730; Belongs to the LOG family.


ensembl_gene_id: HMPREF0299_5470
symbol: dapE
gene_biotype: protein_coding
description:
  Succinyl-diaminopimelate desuccinylase; Identified by match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01900.


ensembl_gene_id: HMPREF0299_5475
symbol: dapD
gene_biotype: protein_coding
description:
  2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.


ensembl_gene_id: HMPREF0299_5478
symbol: dapC
gene_biotype: protein_coding
description:
  Succinyldiaminopimelate transaminase; Identified by match to protein family HMM PF00155; match to protein family HMM TIGR03539.


ensembl_gene_id: HMPREF0299_5479
symbol: fdxA
gene_biotype: protein_coding
description:
  4Fe-4S binding domain protein; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.


ensembl_gene_id: HMPREF0299_5482
symbol: mshB
gene_biotype: protein_coding
description:
  1D-myo-inosityl-2-acetamido-2-deoxy-alpha-D- glucopyranoside deacetylase; Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2- deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.


ensembl_gene_id: HMPREF0299_5484
symbol: typA
gene_biotype: protein_coding
description:
  GTP-binding protein TypA; Identified by match to protein family HMM PF00009; match to protein family HMM PF00679; match to protein family HMM PF03144; match to protein family HMM TIGR00231; match to protein family HMM TIGR01394.


ensembl_gene_id: HMPREF0299_5487
symbol: arsC
gene_biotype: protein_coding
description:
  Arsenate reductase; Identified by match to protein family HMM PF03960; match to protein family HMM TIGR00014; Belongs to the ArsC family.


ensembl_gene_id: HMPREF0299_5495
symbol: EFM48071.1
gene_biotype: protein_coding
description:
  2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.


ensembl_gene_id: HMPREF0299_5501
symbol: EFM47803.1
gene_biotype: protein_coding
description:
  Cupin domain protein; Identified by match to protein family HMM PF02627; match to protein family HMM PF07883.


ensembl_gene_id: HMPREF0299_5512
symbol: EFM47918.1
gene_biotype: protein_coding
description:
  Identified by match to protein family HMM PF01170; match to protein family HMM PF02384; match to protein family HMM PF05175.


ensembl_gene_id: HMPREF0299_5516
symbol: ychF
gene_biotype: protein_coding
description:
  GTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.


ensembl_gene_id: HMPREF0299_5517
symbol: EFM48117.1
gene_biotype: protein_coding
description:
  Identified by match to protein family HMM PF00209; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.


ensembl_gene_id: HMPREF0299_5523
symbol: ispH
gene_biotype: protein_coding
description:
  4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.


ensembl_gene_id: HMPREF0299_5524
symbol: xseA
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease VII, large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family.


ensembl_gene_id: HMPREF0299_5525
symbol: xseB
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease VII, small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.


ensembl_gene_id: HMPREF0299_5527
symbol: glpX
gene_biotype: protein_coding
description:
  Fructose-1,6-bisphosphatase, class II; Identified by match to protein family HMM PF03320; match to protein family HMM TIGR00330.


ensembl_gene_id: HMPREF0299_5528
symbol: fumC
gene_biotype: protein_coding
description:
  Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.


ensembl_gene_id: HMPREF0299_5532
symbol: pabB
gene_biotype: protein_coding
description:
  Aminodeoxychorismate synthase, component I; Identified by match to protein family HMM PF00117; match to protein family HMM PF00425; match to protein family HMM PF04715; match to protein family HMM TIGR00553; match to protein family HMM TIGR00566.


ensembl_gene_id: HMPREF0299_5533
symbol: glyA
gene_biotype: protein_coding
description:
  Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.


ensembl_gene_id: HMPREF0299_5534
symbol: coaA
gene_biotype: protein_coding
description:
  Pantothenate kinase; Identified by match to protein family HMM PF00485; match to protein family HMM TIGR00554.


ensembl_gene_id: HMPREF0299_5536
symbol: uppS
gene_biotype: protein_coding
description:
  Di-trans,poly-cis-decaprenylcistransferase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.


ensembl_gene_id: HMPREF0299_5538
symbol: mca
gene_biotype: protein_coding
description:
  Mycothiol conjugate amidase Mca; A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S- conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics; Belongs to the MshB deacetylase family. Mca subfamily.


ensembl_gene_id: HMPREF0299_5540
symbol: greA
gene_biotype: protein_coding
description:
  Transcription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.


ensembl_gene_id: HMPREF0299_5542
symbol: ripA
gene_biotype: protein_coding
description:
  HTH-type transcriptional repressor of iron protein A; Identified by match to protein family HMM PF00165.


ensembl_gene_id: HMPREF0299_5549
symbol: eno
gene_biotype: protein_coding
description:
  Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.


ensembl_gene_id: HMPREF0299_5551
symbol: EFM47846.1
gene_biotype: protein_coding
description:
  MazG nucleotide pyrophosphohydrolase domain protein; Identified by match to protein family HMM PF03819.


ensembl_gene_id: HMPREF0299_5552
symbol: lysI
gene_biotype: protein_coding
description:
  L-lysine transport protein; Identified by match to protein family HMM PF00324; match to protein family HMM TIGR00905.


ensembl_gene_id: HMPREF0299_5553
symbol: mfd
gene_biotype: protein_coding
description:
  Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.


ensembl_gene_id: HMPREF0299_5564
symbol: EFM47893.1
gene_biotype: protein_coding
description:
  Oxidoreductase, short chain dehydrogenase/reductase family protein; Identified by match to protein family HMM PF00106.


ensembl_gene_id: HMPREF0299_5565
symbol: glmU
gene_biotype: protein_coding
description:
  UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.


ensembl_gene_id: HMPREF0299_5566
symbol: EFM48102.1
gene_biotype: protein_coding
description:
  Tat pathway signal sequence domain protein; Identified by match to protein family HMM PF07731; match to protein family HMM PF07732; match to protein family HMM TIGR01409.


ensembl_gene_id: HMPREF0299_5567
symbol: prs
gene_biotype: protein_coding
description:
  Ribose-phosphate diphosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.


ensembl_gene_id: HMPREF0299_5569
symbol: rplY
gene_biotype: protein_coding
description:
  Ribosomal protein L25, Ctc-form; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.


ensembl_gene_id: HMPREF0299_5572
symbol: pth
gene_biotype: protein_coding
description:
  aminoacyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.


ensembl_gene_id: HMPREF0299_5575
symbol: prfC
gene_biotype: protein_coding
description:
  Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.


ensembl_gene_id: HMPREF0299_5578
symbol: gap
gene_biotype: protein_coding
description:
  Glyceraldehyde-3-phosphate dehydrogenase, type I; Identified by match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01534; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.


ensembl_gene_id: HMPREF0299_5579
symbol: EFM47794.1
gene_biotype: protein_coding
description:
  Aldehyde dehydrogenase (NAD) family protein; Identified by match to protein family HMM PF00171; match to protein family HMM PF01619; Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: HMPREF0299_5586
symbol: EFM47878.1
gene_biotype: protein_coding
description:
  Cof-like hydrolase; Identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484.


ensembl_gene_id: HMPREF0299_5587
symbol: ppk2
gene_biotype: protein_coding
description:
  Polyphosphate kinase 2; Identified by match to protein family HMM PF03976; match to protein family HMM TIGR03707.


ensembl_gene_id: HMPREF0299_5590
symbol: ispE
gene_biotype: protein_coding
description:
  4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.


ensembl_gene_id: HMPREF0299_5591
symbol: ksgA
gene_biotype: protein_coding
description:
  Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.


ensembl_gene_id: HMPREF0299_5592
symbol: EFM48128.1
gene_biotype: protein_coding
description:
  Transcriptional regulator, GntR family; Identified by match to protein family HMM PF00392; match to protein family HMM PF07729.


ensembl_gene_id: HMPREF0299_5593
symbol: EFM48008.1
gene_biotype: protein_coding
description:
  Tat pathway signal sequence domain protein; Identified by match to protein family HMM PF00496; match to protein family HMM TIGR01409.


ensembl_gene_id: HMPREF0299_5595
symbol: EFM47993.1
gene_biotype: protein_coding
description:
  Transglycosylase-like domain protein; Identified by match to protein family HMM PF03990; match to protein family HMM PF06737; match to protein family HMM PF07501.


ensembl_gene_id: HMPREF0299_5596
symbol: EFM48106.1
gene_biotype: protein_coding
description:
  Hydrolase, TatD family; Identified by match to protein family HMM PF01026; match to protein family HMM TIGR00010.


ensembl_gene_id: HMPREF0299_5597
symbol: metG
gene_biotype: protein_coding
description:
  methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.


ensembl_gene_id: HMPREF0299_5598
symbol: rsmI
gene_biotype: protein_coding
description:
  S-adenosylmethionine-dependent methyltransferase, YraL family; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.


ensembl_gene_id: HMPREF0299_5600
symbol: EFM48046.1
gene_biotype: protein_coding
description:
  Transporter, betaine/carnitine/choline family; Identified by match to protein family HMM PF02028; match to protein family HMM TIGR00842; Belongs to the BCCT transporter (TC 2.A.15) family.


ensembl_gene_id: HMPREF0299_5601
symbol: EFM47721.1
gene_biotype: protein_coding
description:
  Dolichyl-phosphate-mannose-protein mannosyltransferase; Identified by match to protein family HMM PF02366.


ensembl_gene_id: HMPREF0299_5608
symbol: EFM47735.1
gene_biotype: protein_coding
description:
  5-formyltetrahydrofolate cyclo-ligase; Identified by match to protein family HMM PF01812; match to protein family HMM TIGR02727; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.


ensembl_gene_id: HMPREF0299_5611
symbol: mscL
gene_biotype: protein_coding
description:
  Large conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.


ensembl_gene_id: HMPREF0299_5617
symbol: rpmF
gene_biotype: protein_coding
description:
  Ribosomal protein L32; Identified by match to protein family HMM PF01783; match to protein family HMM TIGR01031; Belongs to the bacterial ribosomal protein bL32 family.


ensembl_gene_id: HMPREF0299_5618
symbol: rpmE
gene_biotype: protein_coding
description:
  Ribosomal protein L31; Identified by match to protein family HMM PF01197; match to protein family HMM TIGR00105.


ensembl_gene_id: HMPREF0299_5619
symbol: rpmB
gene_biotype: protein_coding
description:
  Ribosomal protein L28; Identified by match to protein family HMM PF00830; match to protein family HMM TIGR00009; Belongs to the bacterial ribosomal protein bL28 family.


ensembl_gene_id: HMPREF0299_5620
symbol: rpmG
gene_biotype: protein_coding
description:
  Ribosomal protein L33; Identified by match to protein family HMM PF00471; match to protein family HMM TIGR01023; Belongs to the bacterial ribosomal protein bL33 family.


ensembl_gene_id: HMPREF0299_5621
symbol: rpsN
gene_biotype: protein_coding
description:
  Ribosomal protein S14p/S29e; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family.


ensembl_gene_id: HMPREF0299_5622
symbol: rpsR
gene_biotype: protein_coding
description:
  Ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.


ensembl_gene_id: HMPREF0299_5625
symbol: EFM47940.1
gene_biotype: protein_coding
description:
  HpcH/HpaI aldolase/citrate lyase family protein; Identified by match to protein family HMM PF03328; Belongs to the HpcH/HpaI aldolase family.


ensembl_gene_id: HMPREF0299_5626
symbol: EFM48100.1
gene_biotype: protein_coding
description:
  Transcriptional regulator, AbrB family; Identified by match to protein family HMM PF04014; match to protein family HMM TIGR01439.


ensembl_gene_id: HMPREF0299_5630
symbol: purH
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Identified by match to protein family HMM PF01808; match to protein family HMM PF02142; match to protein family HMM TIGR00355.


ensembl_gene_id: HMPREF0299_5631
symbol: purN
gene_biotype: protein_coding
description:
  Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.


ensembl_gene_id: HMPREF0299_5641
symbol: EFM48149.1
gene_biotype: protein_coding
description:
  Succinate-semialdehyde dehydrogenase; Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: HMPREF0299_5643
symbol: EFM47875.1
gene_biotype: protein_coding
description:
  NAD dependent epimerase/dehydratase family protein; Identified by match to protein family HMM PF01370; match to protein family HMM PF05368.


ensembl_gene_id: HMPREF0299_5644
symbol: pgi
gene_biotype: protein_coding
description:
  Glucose-6-phosphate isomerase; Identified by match to protein family HMM PF00342; Belongs to the GPI family.


ensembl_gene_id: HMPREF0299_5645
symbol: EFM48026.1
gene_biotype: protein_coding
description:
  Oxidoreductase, short chain dehydrogenase/reductase family protein; Identified by match to protein family HMM PF00106; match to protein family HMM PF01370; match to protein family HMM PF05368; match to protein family HMM PF07993.


ensembl_gene_id: HMPREF0299_5649
symbol: EFM47724.1
gene_biotype: protein_coding
description:
  Formamidopyrimidine-DNA glycosylase N-terminal domain protein; Identified by match to protein family HMM PF01149; match to protein family HMM PF06831.


ensembl_gene_id: HMPREF0299_5650
symbol: EFM48033.1
gene_biotype: protein_coding
description:
  Putative bacteriochlorophyll 4-vinyl reductase; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF08494.


ensembl_gene_id: HMPREF0299_5653
symbol: thyA
gene_biotype: protein_coding
description:
  Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.


ensembl_gene_id: HMPREF0299_5654
symbol: folA
gene_biotype: protein_coding
description:
  Dihydrofolate reductase; Identified by match to protein family HMM PF00186; Belongs to the dihydrofolate reductase family.


ensembl_gene_id: HMPREF0299_5655
symbol: EFM47773.1
gene_biotype: protein_coding
description:
  Glutaredoxin; Identified by match to protein family HMM PF00462; match to protein family HMM TIGR02200.


ensembl_gene_id: HMPREF0299_5656
symbol: cobF
gene_biotype: protein_coding
description:
  precorrin-6A synthase (deacetylating); Identified by match to protein family HMM PF00590; match to protein family HMM TIGR02434.


ensembl_gene_id: HMPREF0299_5664
symbol: EFM48058.1
gene_biotype: protein_coding
description:
  Tat pathway signal sequence domain protein; Identified by match to protein family HMM PF08924; match to protein family HMM TIGR01409.


ensembl_gene_id: HMPREF0299_5666
symbol: EFM48116.1
gene_biotype: protein_coding
description:
  Identified by match to protein family HMM PF00378; Belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: HMPREF0299_5668
symbol: EFM48025.1
gene_biotype: protein_coding
description:
  Putative acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Identified by match to protein family HMM PF00378; match to protein family HMM PF01039.


ensembl_gene_id: HMPREF0299_5670
symbol: gltA
gene_biotype: protein_coding
description:
  Citrate (Si)-synthase; Identified by match to protein family HMM PF00285; match to protein family HMM TIGR01798; Belongs to the citrate synthase family.


ensembl_gene_id: HMPREF0299_5672
symbol: EFM47887.1
gene_biotype: protein_coding
description:
  Putative phosphoserine transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine.


ensembl_gene_id: HMPREF0299_5709
symbol: EFM50197.1
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; Identified by match to protein family HMM PF00126; match to protein family HMM PF03466; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: HMPREF0299_5711
symbol: EFM50178.1
gene_biotype: protein_coding
description:
  3-methyladenine DNA glycosylase; Identified by match to protein family HMM PF02245; match to protein family HMM TIGR00567; Belongs to the DNA glycosylase MPG family.


ensembl_gene_id: HMPREF0299_5713
symbol: EFM50230.1
gene_biotype: protein_coding
description:
  Bacterial transferase hexapeptide repeat protein; Identified by match to protein family HMM PF00132.


ensembl_gene_id: HMPREF0299_5715
symbol: cobB-2
gene_biotype: protein_coding
description:
  Transcriptional regulator, Sir2 family; Identified by match to protein family HMM PF02146; Belongs to the sirtuin family. Class III subfamily.


ensembl_gene_id: HMPREF0299_5716
symbol: EFM50241.1
gene_biotype: protein_coding
description:
  Identified by match to protein family HMM PF00583; match to protein family HMM PF03641; match to protein family HMM TIGR00730.


ensembl_gene_id: HMPREF0299_5722
symbol: EFM49920.1
gene_biotype: protein_coding
description:
  Sigma-70 region 2; Identified by match to protein family HMM PF04542; match to protein family HMM PF04545; match to protein family HMM PF08281; match to protein family HMM TIGR02937; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: HMPREF0299_5732
symbol: EFM50284.1
gene_biotype: protein_coding
description:
  ATPase family associated with various cellular activities (AAA); Identified by match to protein family HMM PF01078; match to protein family HMM PF07726; match to protein family HMM PF07728.


ensembl_gene_id: HMPREF0299_5735
symbol: tag
gene_biotype: protein_coding
description:
  DNA-3-methyladenine glycosylase I; Identified by match to protein family HMM PF00106; match to protein family HMM PF01370; match to protein family HMM PF03352; match to protein family HMM PF08659; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: HMPREF0299_5736
symbol: hrpB
gene_biotype: protein_coding
description:
  ATP-dependent helicase HrpB; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF08482; match to protein family HMM TIGR01970.


ensembl_gene_id: HMPREF0299_5740
symbol: EFM50001.1
gene_biotype: protein_coding
description:
  6-O-methylguanine DNA methyltransferase, DNA binding domain protein; Identified by match to protein family HMM PF01035.


ensembl_gene_id: HMPREF0299_5746
symbol: EFM49926.1
gene_biotype: protein_coding
description:
  Peptidase family M13; Identified by match to protein family HMM PF01431; match to protein family HMM PF05649.


ensembl_gene_id: HMPREF0299_5751
symbol: EFM49840.1
gene_biotype: protein_coding
description:
  Mycobacterial cell wall arabinan synthesis protein; Identified by match to protein family HMM PF04602.


ensembl_gene_id: HMPREF0299_5761
symbol: EFM49787.1
gene_biotype: protein_coding
description:
  ABC transporter, substrate-binding protein; Identified by match to protein family HMM PF01297; Belongs to the bacterial solute-binding protein 9 family.


ensembl_gene_id: HMPREF0299_5766
symbol: EFM49796.1
gene_biotype: protein_coding
description:
  Siderophore biosynthesis protein, IucA/IucC family; Identified by match to protein family HMM PF04183.


ensembl_gene_id: HMPREF0299_5771
symbol: EFM49838.1
gene_biotype: protein_coding
description:
  NAD(P)H quinone oxidoreductase, PIG3 family; Identified by match to protein family HMM PF00107; match to protein family HMM PF08240; match to protein family HMM TIGR02824.


ensembl_gene_id: HMPREF0299_5779
symbol: hisC
gene_biotype: protein_coding
description:
  Histidinol-phosphate transaminase; May catalyze the transamination reaction in phenylalanine biosynthesis; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: HMPREF0299_5783
symbol: EFM50153.1
gene_biotype: protein_coding
description:
  FAD linked oxidase, C-terminal domain protein; Identified by match to protein family HMM PF00037; match to protein family HMM PF01565; match to protein family HMM PF02913.


ensembl_gene_id: HMPREF0299_5788
symbol: EFM50275.1
gene_biotype: protein_coding
description:
  Glycosyl hydrolase family 25; Identified by match to protein family HMM PF01183; match to protein family HMM PF01551.


ensembl_gene_id: HMPREF0299_5790
symbol: EFM50050.1
gene_biotype: protein_coding
description:
  Putative tRNA adenosine deaminase-associated protein; Identified by match to protein family HMM TIGR03941.


ensembl_gene_id: HMPREF0299_5791
symbol: tadA
gene_biotype: protein_coding
description:
  Cytidine and deoxycytidylate deaminase zinc-binding region; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.


ensembl_gene_id: HMPREF0299_5799
symbol: tgt
gene_biotype: protein_coding
description:
  tRNA-guanine transglycosylase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the [...]


ensembl_gene_id: HMPREF0299_5800
symbol: EFM49843.1
gene_biotype: protein_coding
description:
  Putative membrane protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.


ensembl_gene_id: HMPREF0299_5803
symbol: gluQ
gene_biotype: protein_coding
description:
  glutamyl-Q tRNA(Asp) synthetase; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.


ensembl_gene_id: HMPREF0299_5809
symbol: dnaX
gene_biotype: protein_coding
description:
  DNA polymerase III, subunit gamma and tau; Identified by match to protein family HMM PF00004; match to protein family HMM TIGR02397.


ensembl_gene_id: HMPREF0299_5810
symbol: EFM50210.1
gene_biotype: protein_coding
description:
  DNA-binding protein, YbaB/EbfC family; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.


ensembl_gene_id: HMPREF0299_5812
symbol: recR
gene_biotype: protein_coding
description:
  Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.


ensembl_gene_id: HMPREF0299_5814
symbol: EFM50190.1
gene_biotype: protein_coding
description:
  Mur ligase middle domain protein; Identified by match to protein family HMM PF08245; match to protein family HMM PF08353.


ensembl_gene_id: HMPREF0299_5816
symbol: leuA
gene_biotype: protein_coding
description:
  2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.


ensembl_gene_id: HMPREF0299_5821
symbol: EFM50086.1
gene_biotype: protein_coding
description:
  Aspartate kinase, monofunctional class; Identified by match to protein family HMM PF00696; match to protein family HMM PF01842; match to protein family HMM TIGR00656; match to protein family HMM TIGR00657; Belongs to the aspartokinase family.


ensembl_gene_id: HMPREF0299_5822
symbol: asd
gene_biotype: protein_coding
description:
  Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.


ensembl_gene_id: HMPREF0299_5827
symbol: ahpD
gene_biotype: protein_coding
description:
  Alkyl hydroperoxide reductase AhpD; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.


ensembl_gene_id: HMPREF0299_5828
symbol: EFM50294.1
gene_biotype: protein_coding
description:
  Antioxidant, AhpC/TSA family; Identified by match to protein family HMM PF00578; match to protein family HMM PF08534.


ensembl_gene_id: HMPREF0299_5832
symbol: EFM49880.1
gene_biotype: protein_coding
description:
  Putative monovalent cation/H+ antiporter subunit E; Identified by match to protein family HMM PF01899.


ensembl_gene_id: HMPREF0299_5833
symbol: EFM50270.1
gene_biotype: protein_coding
description:
  Putative monovalent cation/H+ antiporter subunit D; Identified by match to protein family HMM PF00361.


ensembl_gene_id: HMPREF0299_5834
symbol: EFM50171.1
gene_biotype: protein_coding
description:
  Putative monovalent cation/H+ antiporter subunit C; Identified by match to protein family HMM PF00420.


ensembl_gene_id: HMPREF0299_5835
symbol: EFM49855.1
gene_biotype: protein_coding
description:
  NADH-ubiquinone/plastoquinone (complex I) family protein; Identified by match to protein family HMM PF00361; match to protein family HMM PF04039.


ensembl_gene_id: HMPREF0299_5837
symbol: EFM49801.1
gene_biotype: protein_coding
description:
  Oligopeptide transporter, OPT family; Identified by match to protein family HMM PF03169; match to protein family HMM TIGR00728; match to protein family HMM TIGR00733.


ensembl_gene_id: HMPREF0299_5838
symbol: EFM50033.1
gene_biotype: protein_coding
description:
  HAMP domain protein; Identified by match to protein family HMM PF00211; match to protein family HMM PF00672.


ensembl_gene_id: HMPREF0299_5852
symbol: rmlD
gene_biotype: protein_coding
description:
  NAD dependent epimerase/dehydratase family protein; Identified by match to protein family HMM PF00106; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF04321; match to protein family HMM PF07993.


ensembl_gene_id: HMPREF0299_5858
symbol: rfbA
gene_biotype: protein_coding
description:
  Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.


ensembl_gene_id: HMPREF0299_5859
symbol: EFM49798.1
gene_biotype: protein_coding
description:
  Putative dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.


ensembl_gene_id: HMPREF0299_5861
symbol: rfbB
gene_biotype: protein_coding
description:
  dTDP-glucose 4,6-dehydratase; Identified by match to protein family HMM PF00106; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993; match to protein family HMM TIGR01181; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.


ensembl_gene_id: HMPREF0299_5866
symbol: lpdA
gene_biotype: protein_coding
description:
  Dihydrolipoyl dehydrogenase; Identified by match to protein family HMM PF00070; match to protein family HMM PF01134; match to protein family HMM PF02852; match to protein family HMM PF07992; match to protein family HMM TIGR01350.


ensembl_gene_id: HMPREF0299_5867
symbol: sdhC
gene_biotype: protein_coding
description:
  Succinate dehydrogenase cytochrome B subunit, b558 family; Identified by match to protein family HMM TIGR02046.


ensembl_gene_id: HMPREF0299_5868
symbol: sdhA
gene_biotype: protein_coding
description:
  Succinate dehydrogenase flavoprotein subunit; Identified by match to protein family HMM PF00890; match to protein family HMM PF02910; match to protein family HMM TIGR01811.


ensembl_gene_id: HMPREF0299_5869
symbol: EFM49836.1
gene_biotype: protein_coding
description:
  Succinate dehydrogenase/fumarate reductase iron-sulfur subunit; Identified by match to protein family HMM PF00037; match to protein family HMM TIGR00384.


ensembl_gene_id: HMPREF0299_5879
symbol: mshA
gene_biotype: protein_coding
description:
  UDP-N-acetylglucosamine: 1L-myo-inositol-1-phosphate 1-alpha-D-N-acetylglucosaminyltransferase; Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2- deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.


ensembl_gene_id: HMPREF0299_5880
symbol: EFM50262.1
gene_biotype: protein_coding
description:
  Oxidoreductase, short chain dehydrogenase/reductase family protein; Identified by match to protein family HMM PF00106; match to protein family HMM PF08659; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: HMPREF0299_5883
symbol: gpmA
gene_biotype: protein_coding
description:
  Phosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.


ensembl_gene_id: HMPREF0299_5887
symbol: proC
gene_biotype: protein_coding
description:
  Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.


ensembl_gene_id: HMPREF0299_5888
symbol: EFM49956.1
gene_biotype: protein_coding
description:
  HAD hydrolase, family IB; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01488; match to protein family HMM TIGR01490.


ensembl_gene_id: HMPREF0299_5890
symbol: hemA
gene_biotype: protein_coding
description:
  glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).


ensembl_gene_id: HMPREF0299_5891
symbol: hemC
gene_biotype: protein_coding
description:
  Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.


ensembl_gene_id: HMPREF0299_5892
symbol: hemD
gene_biotype: protein_coding
description:
  uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.


ensembl_gene_id: HMPREF0299_5893
symbol: hemB
gene_biotype: protein_coding
description:
  Porphobilinogen synthase; Identified by match to protein family HMM PF00490; Belongs to the ALAD family.


ensembl_gene_id: HMPREF0299_5895
symbol: EFM49752.1
gene_biotype: protein_coding
description:
  E1-E2 ATPase; Identified by match to protein family HMM PF00122; match to protein family HMM PF00702.


ensembl_gene_id: HMPREF0299_5898
symbol: hemE
gene_biotype: protein_coding
description:
  Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.


ensembl_gene_id: HMPREF0299_5899
symbol: hemG
gene_biotype: protein_coding
description:
  Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.


ensembl_gene_id: HMPREF0299_5901
symbol: EFM50055.1
gene_biotype: protein_coding
description:
  Putative dihydrodipicolinate reductase domain protein; Identified by match to protein family HMM PF01113.


ensembl_gene_id: HMPREF0299_5902
symbol: hemL
gene_biotype: protein_coding
description:
  Glutamate-1-semialdehyde-2,1-aminomutase; Identified by match to protein family HMM PF00155; match to protein family HMM PF00202; match to protein family HMM TIGR00713.


ensembl_gene_id: HMPREF0299_5905
symbol: EFM50239.1
gene_biotype: protein_coding
description:
  Cytochrome C biogenesis protein transmembrane region; Identified by match to protein family HMM PF02683.


ensembl_gene_id: HMPREF0299_5907
symbol: ccsB
gene_biotype: protein_coding
description:
  Cytochrome c-type biogenesis protein CcsB; Identified by match to protein family HMM PF01578; match to protein family HMM TIGR03144.


ensembl_gene_id: HMPREF0299_5911
symbol: menA
gene_biotype: protein_coding
description:
  1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily.


ensembl_gene_id: HMPREF0299_5913
symbol: menB
gene_biotype: protein_coding
description:
  Naphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA); Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.


ensembl_gene_id: HMPREF0299_5914
symbol: menC
gene_biotype: protein_coding
description:
  Mandelate racemase/muconate lactonizing enzyme, C-terminal domain protein; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB).


ensembl_gene_id: HMPREF0299_5916
symbol: menD
gene_biotype: protein_coding
description:
  2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily.


ensembl_gene_id: HMPREF0299_5919
symbol: ubiE
gene_biotype: protein_coding
description:
  Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).


ensembl_gene_id: HMPREF0299_5920
symbol: EFM49745.1
gene_biotype: protein_coding
description:
  Geranylgeranyl reductase family; Identified by match to protein family HMM PF01494; match to protein family HMM TIGR02032.


ensembl_gene_id: HMPREF0299_5921
symbol: EFM49914.1
gene_biotype: protein_coding
description:
  Polyprenyl synthetase; Identified by match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family.


ensembl_gene_id: HMPREF0299_5926
symbol: secE
gene_biotype: protein_coding
description:
  Preprotein translocase, SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.


ensembl_gene_id: HMPREF0299_5927
symbol: nusG
gene_biotype: protein_coding
description:
  Transcription termination/antitermination factor NusG; Participates in transcription elongation, termination and antitermination.


ensembl_gene_id: HMPREF0299_5928
symbol: rplK
gene_biotype: protein_coding
description:
  Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.


ensembl_gene_id: HMPREF0299_5929
symbol: rplA
gene_biotype: protein_coding
description:
  Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.


ensembl_gene_id: HMPREF0299_5938
symbol: rplJ
gene_biotype: protein_coding
description:
  Ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.


ensembl_gene_id: HMPREF0299_5939
symbol: rplL
gene_biotype: protein_coding
description:
  Ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family.


ensembl_gene_id: HMPREF0299_5941
symbol: rpoB
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: HMPREF0299_5942
symbol: rpoC
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: HMPREF0299_5943
symbol: cas2
gene_biotype: protein_coding
description:
  CRISPR-associated endoribonuclease Cas2; Identified by match to protein family HMM PF09707; match to protein family HMM TIGR01873.


ensembl_gene_id: HMPREF0299_5944
symbol: cas1
gene_biotype: protein_coding
description:
  CRISPR-associated endonuclease Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.


ensembl_gene_id: HMPREF0299_5945
symbol: cas3
gene_biotype: protein_coding
description:
  CRISPR-associated helicase Cas3; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by match to protein family HMM PF00271; match to protein family HMM TIGR01587; match to protein family HMM TIGR01596.


ensembl_gene_id: HMPREF0299_5949
symbol: casC
gene_biotype: protein_coding
description:
  CRISPR system CASCADE complex protein CasC; Identified by match to protein family HMM PF09344; match to protein family HMM TIGR01869.


ensembl_gene_id: HMPREF0299_5950
symbol: casD
gene_biotype: protein_coding
description:
  CRISPR system CASCADE complex protein CasD; Identified by match to protein family HMM PF09708; match to protein family HMM TIGR01868; match to protein family HMM TIGR02593.


ensembl_gene_id: HMPREF0299_5958
symbol: galE
gene_biotype: protein_coding
description:
  UDP-glucose 4-epimerase; Identified by match to protein family HMM PF00106; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM TIGR01179.


ensembl_gene_id: HMPREF0299_5960
symbol: EFM50007.1
gene_biotype: protein_coding
description:
  Anaerobic ribonucleoside-triphosphate reductase activating protein; Identified by match to protein family HMM PF04055; match to protein family HMM TIGR02495.


ensembl_gene_id: HMPREF0299_5961
symbol: nrdD
gene_biotype: protein_coding
description:
  Anaerobic ribonucleoside-triphosphate reductase; Identified by match to protein family HMM TIGR02487.


ensembl_gene_id: HMPREF0299_5965
symbol: EFM50298.1
gene_biotype: protein_coding
description:
  Histidine kinase; Identified by match to protein family HMM PF02518; match to protein family HMM PF07730.


ensembl_gene_id: HMPREF0299_5971
symbol: EFM49878.1
gene_biotype: protein_coding
description:
  ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005; match to protein family HMM PF08402; Belongs to the ABC transporter superfamily.


ensembl_gene_id: HMPREF0299_5972
symbol: pulA
gene_biotype: protein_coding
description:
  Pullulanase, type I; Identified by match to protein family HMM PF00128; match to protein family HMM PF02922; match to protein family HMM TIGR02104; Belongs to the glycosyl hydrolase 13 family.


ensembl_gene_id: HMPREF0299_5974
symbol: EFM49988.1
gene_biotype: protein_coding
description:
  Response regulator receiver domain protein; Identified by match to protein family HMM PF00072; match to protein family HMM PF00196; match to protein family HMM PF08281.


ensembl_gene_id: HMPREF0299_5976
symbol: EFM49740.1
gene_biotype: protein_coding
description:
  Nucleotide sugar dehydrogenase; Identified by match to protein family HMM PF00984; match to protein family HMM PF03720; match to protein family HMM PF03721; match to protein family HMM TIGR03026.


ensembl_gene_id: HMPREF0299_5986
symbol: rpsL
gene_biotype: protein_coding
description:
  Ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.


ensembl_gene_id: HMPREF0299_5988
symbol: rpsG
gene_biotype: protein_coding
description:
  Ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.


ensembl_gene_id: HMPREF0299_5989
symbol: fusA
gene_biotype: protein_coding
description:
  Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...]


ensembl_gene_id: HMPREF0299_5990
symbol: tuf
gene_biotype: protein_coding
description:
  Translation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.


ensembl_gene_id: HMPREF0299_6002
symbol: EFM50245.1
gene_biotype: protein_coding
description:
  Putative phosphonate C-P lyase system protein PhnK; Identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727; Belongs to the ABC transporter superfamily.


ensembl_gene_id: HMPREF0299_6006
symbol: rplC
gene_biotype: protein_coding
description:
  50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.


ensembl_gene_id: HMPREF0299_6008
symbol: rplW
gene_biotype: protein_coding
description:
  Ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.


ensembl_gene_id: HMPREF0299_6009
symbol: rplB
gene_biotype: protein_coding
description:
  Ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.


ensembl_gene_id: HMPREF0299_6010
symbol: rpsS
gene_biotype: protein_coding
description:
  Ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.


ensembl_gene_id: HMPREF0299_6011
symbol: rplV
gene_biotype: protein_coding
description:
  Ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.


ensembl_gene_id: HMPREF0299_6012
symbol: rpsC
gene_biotype: protein_coding
description:
  Ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.


ensembl_gene_id: HMPREF0299_6013
symbol: rplP
gene_biotype: protein_coding
description:
  Ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.


ensembl_gene_id: HMPREF0299_6014
symbol: rpmC
gene_biotype: protein_coding
description:
  Ribosomal protein L29; Identified by match to protein family HMM PF00831; match to protein family HMM TIGR00012; Belongs to the universal ribosomal protein uL29 family.


ensembl_gene_id: HMPREF0299_6015
symbol: rpsQ
gene_biotype: protein_coding
description:
  30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.


ensembl_gene_id: HMPREF0299_6018
symbol: EFM49775.1
gene_biotype: protein_coding
description:
  AMP-binding enzyme; Identified by match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF00668; match to protein family HMM PF00975; match to protein family HMM TIGR01733; Belongs to the ATP-dependent AMP-binding enzyme family.


ensembl_gene_id: HMPREF0299_6021
symbol: dhbE
gene_biotype: protein_coding
description:
  Putative (2,3-dihydroxybenzoyl)adenylate synthase; Identified by match to protein family HMM PF00501.


ensembl_gene_id: HMPREF0299_6022
symbol: EFM49861.1
gene_biotype: protein_coding
description:
  Isochorismate synthase; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00543.


ensembl_gene_id: HMPREF0299_6024
symbol: EFM50010.1
gene_biotype: protein_coding
description:
  2,3-dihydroxybenzoate-2,3-dehydrogenase; Identified by match to protein family HMM PF00106; match to protein family HMM PF01370; match to protein family HMM PF08659.


ensembl_gene_id: HMPREF0299_6030
symbol: EFM50143.1
gene_biotype: protein_coding
description:
  Tat pathway signal sequence domain protein; Identified by match to protein family HMM PF01497; match to protein family HMM TIGR01409.


ensembl_gene_id: HMPREF0299_6033
symbol: EFM49889.1
gene_biotype: protein_coding
description:
  Iron chelate uptake ABC transporter, FeCT family, permease protein; Identified by match to protein family HMM PF01032; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: HMPREF0299_6042
symbol: EFM50128.1
gene_biotype: protein_coding
description:
  Identified by match to protein family HMM PF08212; Belongs to the calycin superfamily. Lipocalin family.


ensembl_gene_id: HMPREF0299_6044
symbol: rplN
gene_biotype: protein_coding
description:
  Ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.


ensembl_gene_id: HMPREF0299_6045
symbol: rplX
gene_biotype: protein_coding
description:
  Ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.


ensembl_gene_id: HMPREF0299_6046
symbol: rplE
gene_biotype: protein_coding
description:
  Ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.


ensembl_gene_id: HMPREF0299_6049
symbol: EFM50002.1
gene_biotype: protein_coding
description:
  Glycosyl hydrolase family 32; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain one or more premature stops and/or frameshifts; identified by match to protein family HMM PF00251.


ensembl_gene_id: HMPREF0299_6050
symbol: EFM49978.1
gene_biotype: protein_coding
description:
  PTS system sucrose-specific IIBC component; Identified by match to protein family HMM PF00358; match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00830; match to protein family HMM TIGR01996.


ensembl_gene_id: HMPREF0299_6059
symbol: thiM
gene_biotype: protein_coding
description:
  Putative hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family.


ensembl_gene_id: HMPREF0299_6060
symbol: thiD
gene_biotype: protein_coding
description:
  Phosphomethylpyrimidine kinase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.


ensembl_gene_id: HMPREF0299_6064
symbol: rpsH
gene_biotype: protein_coding
description:
  Ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.


ensembl_gene_id: HMPREF0299_6065
symbol: rplF
gene_biotype: protein_coding
description:
  Ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.


ensembl_gene_id: HMPREF0299_6066
symbol: rplR
gene_biotype: protein_coding
description:
  Ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.


ensembl_gene_id: HMPREF0299_6067
symbol: rpsE
gene_biotype: protein_coding
description:
  Ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.


ensembl_gene_id: HMPREF0299_6068
symbol: rpmD
gene_biotype: protein_coding
description:
  Ribosomal protein L30; Identified by match to protein family HMM PF00327; match to protein family HMM TIGR01308.


ensembl_gene_id: HMPREF0299_6069
symbol: rplO
gene_biotype: protein_coding
description:
  Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.


ensembl_gene_id: HMPREF0299_6072
symbol: EFM50041.1
gene_biotype: protein_coding
description:
  Tetratricopeptide repeat protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain one or more premature stops and/or frameshifts.


ensembl_gene_id: HMPREF0299_6075
symbol: EFM50012.1
gene_biotype: protein_coding
description:
  Tetratricopeptide repeat protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF0299_6077
symbol: secY
gene_biotype: protein_coding
description:
  Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.


ensembl_gene_id: HMPREF0299_6078
symbol: adk
gene_biotype: protein_coding
description:
  Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.


ensembl_gene_id: HMPREF0299_6080
symbol: map
gene_biotype: protein_coding
description:
  Methionine aminopeptidase, type I; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.


ensembl_gene_id: HMPREF0299_6082
symbol: infA
gene_biotype: protein_coding
description:
  Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.


ensembl_gene_id: HMPREF0299_6084
symbol: rpsM
gene_biotype: protein_coding
description:
  30S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family.


ensembl_gene_id: HMPREF0299_6085
symbol: rpsK
gene_biotype: protein_coding
description:
  30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.


ensembl_gene_id: HMPREF0299_6086
symbol: rpsD
gene_biotype: protein_coding
description:
  Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.


ensembl_gene_id: HMPREF0299_6087
symbol: rpoA
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: HMPREF0299_6088
symbol: rplQ
gene_biotype: protein_coding
description:
  Ribosomal protein L17; Identified by match to protein family HMM PF01196; match to protein family HMM TIGR00059.


ensembl_gene_id: HMPREF0299_6091
symbol: truA
gene_biotype: protein_coding
description:
  tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.


ensembl_gene_id: HMPREF0299_6093
symbol: eccB
gene_biotype: protein_coding
description:
  Type VII secretion protein EccB; Identified by match to protein family HMM PF05108; match to protein family HMM TIGR03919.


ensembl_gene_id: HMPREF0299_6095
symbol: EFM50330.1
gene_biotype: protein_coding
description:
  Putative type VII secretion-associated serine protease mycosin; Identified by match to protein family HMM PF00082; Belongs to the peptidase S8 family.


ensembl_gene_id: HMPREF0299_6096
symbol: eccD
gene_biotype: protein_coding
description:
  Type VII secretion integral membrane protein EccD; Identified by match to protein family HMM TIGR03920.


ensembl_gene_id: HMPREF0299_6097
symbol: eccCa
gene_biotype: protein_coding
description:
  Type VII secretion protein EccCa; Identified by match to protein family HMM PF01580; match to protein family HMM TIGR03924; match to protein family HMM TIGR03925.


ensembl_gene_id: HMPREF0299_6099
symbol: EFM50052.1
gene_biotype: protein_coding
description:
  Type VII secretion-associated protein, Rv3446c family; Identified by match to protein family HMM TIGR03931.


ensembl_gene_id: HMPREF0299_6100
symbol: EFM50220.1
gene_biotype: protein_coding
description:
  WXG100 family type VII secretion target; Identified by match to protein family HMM PF06013; match to protein family HMM TIGR03930; Belongs to the WXG100 family.


ensembl_gene_id: HMPREF0299_6104
symbol: rplM
gene_biotype: protein_coding
description:
  Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.


ensembl_gene_id: HMPREF0299_6105
symbol: rpsI
gene_biotype: protein_coding
description:
  Ribosomal protein S9; Identified by match to protein family HMM PF00380; Belongs to the universal ribosomal protein uS9 family.


ensembl_gene_id: HMPREF0299_6107
symbol: glmM
gene_biotype: protein_coding
description:
  Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.


ensembl_gene_id: HMPREF0299_6114
symbol: pnuC-2
gene_biotype: protein_coding
description:
  Nicotinamide mononucleotide transporter PnuC; Identified by match to protein family HMM PF04973; match to protein family HMM TIGR01528.


ensembl_gene_id: HMPREF0299_6115
symbol: EFM50219.1
gene_biotype: protein_coding
description:
  Putative nicotinamide-nucleotide adenylyltransferase; Identified by match to protein family HMM PF01467; match to protein family HMM TIGR00125.


ensembl_gene_id: HMPREF0299_6116
symbol: alr
gene_biotype: protein_coding
description:
  Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.


ensembl_gene_id: HMPREF0299_6117
symbol: EFM49812.1
gene_biotype: protein_coding
description:
  Hydrolase, P-loop family; Identified by match to protein family HMM PF02367; match to protein family HMM TIGR00150.


ensembl_gene_id: HMPREF0299_6119
symbol: yeaZ
gene_biotype: protein_coding
description:
  Universal bacterial protein YeaZ; Identified by match to protein family HMM PF00814; match to protein family HMM TIGR03725.


ensembl_gene_id: HMPREF0299_6120
symbol: rimI
gene_biotype: protein_coding
description:
  Ribosomal-protein-alanine acetyltransferase; Identified by match to protein family HMM PF00583; match to protein family HMM TIGR01575.


ensembl_gene_id: HMPREF0299_6121
symbol: tsaD
gene_biotype: protein_coding
description:
  Putative glycoprotease GCP; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.


ensembl_gene_id: HMPREF0299_6124
symbol: groS
gene_biotype: protein_coding
description:
  Chaperonin GroS; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.


ensembl_gene_id: HMPREF0299_6125
symbol: groL
gene_biotype: protein_coding
description:
  Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.


ensembl_gene_id: HMPREF0299_6128
symbol: EFM49725.1
gene_biotype: protein_coding
description:
  RNA polymerase sigma factor SigD; Identified by match to protein family HMM PF04542; match to protein family HMM PF04545; match to protein family HMM PF08281; match to protein family HMM TIGR02937; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: HMPREF0299_6130
symbol: EFM50144.1
gene_biotype: protein_coding
description:
  O-acetylhomoserine aminocarboxypropyltransferase; Identified by match to protein family HMM PF01053; match to protein family HMM PF01212; match to protein family HMM TIGR01326.


ensembl_gene_id: HMPREF0299_6132
symbol: EFM50324.1
gene_biotype: protein_coding
description:
  Transporter, major facilitator family protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by match to protein family HMM PF07690.


ensembl_gene_id: HMPREF0299_6138
symbol: metX
gene_biotype: protein_coding
description:
  Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.


ensembl_gene_id: HMPREF0299_6140
symbol: folD
gene_biotype: protein_coding
description:
  Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.


ensembl_gene_id: HMPREF0299_6141
symbol: EFM49874.1
gene_biotype: protein_coding
description:
  Putative RNA methyltransferase, TrmH family, group 2; Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.


ensembl_gene_id: HMPREF0299_6155
symbol: EFM50038.1
gene_biotype: protein_coding
description:
  ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; Identified by match to protein family HMM PF02518; match to protein family HMM PF04024.


ensembl_gene_id: HMPREF0299_6165
symbol: guaB
gene_biotype: protein_coding
description:
  Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.


ensembl_gene_id: HMPREF0299_6169
symbol: EFM49866.1
gene_biotype: protein_coding
description:
  Peptidase family S51; Identified by match to protein family HMM PF03575; Belongs to the peptidase S51 family.


ensembl_gene_id: HMPREF0299_6170
symbol: EFM49829.1
gene_biotype: protein_coding
description:
  Putative bacteriophage protein GP30.3; Identified by match to protein family HMM PF08719; match to protein family HMM TIGR02464.


ensembl_gene_id: HMPREF0299_6172
symbol: EFM49726.1
gene_biotype: protein_coding
description:
  Isocitrate dehydrogenase, NADP-dependent; Identified by match to protein family HMM PF03971; match to protein family HMM TIGR00178; Belongs to the monomeric-type IDH family.


ensembl_gene_id: HMPREF0299_6173
symbol: EFM49893.1
gene_biotype: protein_coding
description:
  Putative exodeoxyribonuclease III; Identified by match to protein family HMM PF03372; match to protein family HMM TIGR00633.


ensembl_gene_id: HMPREF0299_6175
symbol: trpS
gene_biotype: protein_coding
description:
  tryptophan--tRNA ligase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: HMPREF0299_6178
symbol: EFM49888.1
gene_biotype: protein_coding
description:
  Serine-type D-Ala-D-Ala carboxypeptidase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF00768; Belongs to the peptidase S11 family.


ensembl_gene_id: HMPREF0299_6183
symbol: upp
gene_biotype: protein_coding
description:
  Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.


ensembl_gene_id: HMPREF0299_6185
symbol: EFM50118.1
gene_biotype: protein_coding
description:
  Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Identified by match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880.


ensembl_gene_id: HMPREF0299_6186
symbol: EFM50136.1
gene_biotype: protein_coding
description:
  Amidohydrolase; Identified by match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01891.


ensembl_gene_id: HMPREF0299_6187
symbol: EFM50176.1
gene_biotype: protein_coding
description:
  Flavoprotein disulfide reductase; Identified by match to protein family HMM PF00070; match to protein family HMM PF01266; match to protein family HMM PF02852; match to protein family HMM PF07992.


ensembl_gene_id: HMPREF0299_6192
symbol: feoB
gene_biotype: protein_coding
description:
  Ferrous iron transport protein B; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.


ensembl_gene_id: HMPREF0299_6194
symbol: speE
gene_biotype: protein_coding
description:
  Spermine/spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.


ensembl_gene_id: HMPREF0299_6199
symbol: treC
gene_biotype: protein_coding
description:
  Alpha,alpha-phosphotrehalase; Identified by match to protein family HMM PF00128; match to protein family HMM TIGR02403.


ensembl_gene_id: HMPREF0299_6201
symbol: EFM49898.1
gene_biotype: protein_coding
description:
  Phosphotransferase system, EIIB; Identified by match to protein family HMM PF00358; match to protein family HMM PF00367; match to protein family HMM TIGR00830.


ensembl_gene_id: HMPREF0299_6202
symbol: EFM50083.1
gene_biotype: protein_coding
description:
  Carbamoyl-phosphate synthase L chain, ATP binding domain protein; Identified by match to protein family HMM PF00289; match to protein family HMM PF00364; match to protein family HMM PF02222; match to protein family HMM PF02785; match to protein family HMM PF02786.


ensembl_gene_id: HMPREF0299_6207
symbol: maf
gene_biotype: protein_coding
description:
  Septum formation protein Maf; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.


ensembl_gene_id: HMPREF0299_6208
symbol: rbsK
gene_biotype: protein_coding
description:
  Putative ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.


ensembl_gene_id: HMPREF0299_6209
symbol: EFM50129.1
gene_biotype: protein_coding
description:
  RbsD/FucU transport family protein; Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.


ensembl_gene_id: HMPREF0299_6214
symbol: EFM49784.1
gene_biotype: protein_coding
description:
  Sugar-binding domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF00532.


ensembl_gene_id: HMPREF0299_6220
symbol: EFM50271.1
gene_biotype: protein_coding
description:
  biotin--[acetyl-CoA-carboxylase] ligase; Identified by match to protein family HMM PF02237; match to protein family HMM PF03099; match to protein family HMM TIGR00121.


ensembl_gene_id: HMPREF0299_6222
symbol: purK
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).


ensembl_gene_id: HMPREF0299_6223
symbol: purE
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).


ensembl_gene_id: HMPREF0299_6225
symbol: crtI
gene_biotype: protein_coding
description:
  Phytoene desaturase; Identified by match to protein family HMM PF01266; match to protein family HMM PF01593; match to protein family HMM TIGR02734.


ensembl_gene_id: HMPREF0299_6233
symbol: EFM49750.1
gene_biotype: protein_coding
description:
  ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005; match to protein family HMM PF03459; match to protein family HMM PF08402; Belongs to the ABC transporter superfamily.


ensembl_gene_id: HMPREF0299_6234
symbol: EFM50181.1
gene_biotype: protein_coding
description:
  Oxidoreductase, zinc-binding dehydrogenase family protein; Identified by match to protein family HMM PF00107.


ensembl_gene_id: HMPREF0299_6238
symbol: EFM49793.1
gene_biotype: protein_coding
description:
  Cell envelope-like function transcriptional attenuator common domain protein; Identified by match to protein family HMM PF03816; match to protein family HMM TIGR00350.


ensembl_gene_id: HMPREF0299_6240
symbol: EFM49961.1
gene_biotype: protein_coding
description:
  Nucleotidyl transferase; Identified by match to protein family HMM PF00132; match to protein family HMM PF00483.


ensembl_gene_id: HMPREF0299_6243
symbol: manB
gene_biotype: protein_coding
description:
  Phosphomannomutase/phosphoglucomutase; Identified by match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880.


ensembl_gene_id: HMPREF0299_6245
symbol: manA
gene_biotype: protein_coding
description:
  Mannose-6-phosphate isomerase, class I; Identified by match to protein family HMM PF01238; match to protein family HMM TIGR00218.


ensembl_gene_id: HMPREF0299_6248
symbol: ahcY
gene_biotype: protein_coding
description:
  Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.


ensembl_gene_id: HMPREF0299_6250
symbol: tmk
gene_biotype: protein_coding
description:
  dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.


ensembl_gene_id: HMPREF0299_6255
symbol: raiA
gene_biotype: protein_coding
description:
  Ribosomal subunit interface protein; Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.


ensembl_gene_id: HMPREF0299_6256
symbol: secA
gene_biotype: protein_coding
description:
  Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.


ensembl_gene_id: HMPREF0299_6262
symbol: EFM50036.1
gene_biotype: protein_coding
description:
  Putative ribosome small subunit-dependent GTPase A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.


ensembl_gene_id: HMPREF0299_6263
symbol: aroA
gene_biotype: protein_coding
description:
  3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.


ensembl_gene_id: HMPREF0299_6265
symbol: EFM49807.1
gene_biotype: protein_coding
description:
  Identified by match to protein family HMM PF04073; match to protein family HMM TIGR00011; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.


ensembl_gene_id: HMPREF0299_6266
symbol: EFM49723.1
gene_biotype: protein_coding
description:
  RNA polymerase sigma-70 factor; Identified by match to protein family HMM PF04542; match to protein family HMM PF04545; match to protein family HMM PF08281; match to protein family HMM TIGR02937; match to protein family HMM TIGR02947; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: HMPREF0299_6269
symbol: maoC
gene_biotype: protein_coding
description:
  Identified by match to protein family HMM PF00109; match to protein family HMM PF00698; match to protein family HMM PF01575; match to protein family HMM PF02801; match to protein family HMM PF08354.


ensembl_gene_id: HMPREF0299_6272
symbol: EFM49900.1
gene_biotype: protein_coding
description:
  DEAD/DEAH box helicase; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; Belongs to the DEAD box helicase family.


ensembl_gene_id: HMPREF0299_6276
symbol: EFM50023.1
gene_biotype: protein_coding
description:
  UvrD/REP helicase; Identified by match to protein family HMM PF00580; Belongs to the helicase family. UvrD subfamily.


ensembl_gene_id: HMPREF0299_6277
symbol: EFM49727.1
gene_biotype: protein_coding
description:
  Putative phage prohead protease, HK97 family; Identified by match to protein family HMM PF00580; Belongs to the helicase family. UvrD subfamily.


ensembl_gene_id: HMPREF0299_6279
symbol: EFM50172.1
gene_biotype: protein_coding
description:
  TrkA N-terminal domain protein; Identified by match to protein family HMM PF02254; match to protein family HMM PF07885.


ensembl_gene_id: HMPREF0299_6281
symbol: EFM49975.1
gene_biotype: protein_coding
description:
  HRDC domain protein; Identified by match to protein family HMM PF00570; match to protein family HMM PF00580.


ensembl_gene_id: HMPREF0299_6295
symbol: EFM50224.1
gene_biotype: protein_coding
description:
  Restriction endonuclease; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF04471.


ensembl_gene_id: HMPREF0299_6301
symbol: EFM50257.1
gene_biotype: protein_coding
description:
  methylmalonyl-CoA carboxyltransferase 5S subunit; Identified by match to protein family HMM PF00682; match to protein family HMM PF02436.


ensembl_gene_id: HMPREF0299_6303
symbol: EFM49730.1
gene_biotype: protein_coding
description:
  methylmalonyl-CoA carboxyltransferase 12S subunit; Identified by match to protein family HMM PF01039.


ensembl_gene_id: HMPREF0299_6305
symbol: EFM50216.1
gene_biotype: protein_coding
description:
  methylmalonyl-CoA carboxyltransferase 1.3S subunit; Identified by match to protein family HMM PF00364.


ensembl_gene_id: HMPREF0299_6309
symbol: hisN
gene_biotype: protein_coding
description:
  Histidinol-phosphate phosphatase HisN; Identified by match to protein family HMM PF00459; match to protein family HMM TIGR02067.


ensembl_gene_id: HMPREF0299_6311
symbol: prfB
gene_biotype: protein_coding
description:
  Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.


ensembl_gene_id: HMPREF0299_6312
symbol: ftsE
gene_biotype: protein_coding
description:
  Putative cell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division.


ensembl_gene_id: HMPREF0299_6313
symbol: EFM50227.1
gene_biotype: protein_coding
description:
  Efflux ABC transporter, permease protein; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.


ensembl_gene_id: HMPREF0299_6314
symbol: smpB
gene_biotype: protein_coding
description:
  SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]


ensembl_gene_id: HMPREF0299_6331
symbol: EFM48475.1
gene_biotype: protein_coding
description:
  HAD hydrolase, family IIA; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01460.


ensembl_gene_id: HMPREF0299_6333
symbol: rrmJ
gene_biotype: protein_coding
description:
  Putative ribosomal RNA large subunit methyltransferase J; Identified by match to protein family HMM PF01479; match to protein family HMM PF01728; match to protein family HMM TIGR00478.


ensembl_gene_id: HMPREF0299_6334
symbol: nadK
gene_biotype: protein_coding
description:
  NAD(+)/NADH kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.


ensembl_gene_id: HMPREF0299_6339
symbol: xerD
gene_biotype: protein_coding
description:
  Tyrosine recombinase XerD; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.


ensembl_gene_id: HMPREF0299_6341
symbol: EFM48916.1
gene_biotype: protein_coding
description:
  ScpA/B protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.


ensembl_gene_id: HMPREF0299_6343
symbol: scpB
gene_biotype: protein_coding
description:
  Segregation and condensation protein B; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.


ensembl_gene_id: HMPREF0299_6344
symbol: EFM48623.1
gene_biotype: protein_coding
description:
  Pseudouridylate synthase; Identified by match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00093; Belongs to the pseudouridine synthase RsuA family.


ensembl_gene_id: HMPREF0299_6345
symbol: cmk
gene_biotype: protein_coding
description:
  Cytidylate kinase; Identified by match to protein family HMM PF02224; match to protein family HMM TIGR00017.


ensembl_gene_id: HMPREF0299_6346
symbol: der
gene_biotype: protein_coding
description:
  Ribosome biogenesis GTPase Der; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.


ensembl_gene_id: HMPREF0299_6351
symbol: EFM48979.1
gene_biotype: protein_coding
description:
  FAD dependent oxidoreductase; Identified by match to protein family HMM PF01266; match to protein family HMM PF01494; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.


ensembl_gene_id: HMPREF0299_6352
symbol: glpK
gene_biotype: protein_coding
description:
  Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.


ensembl_gene_id: HMPREF0299_6356
symbol: secA-2
gene_biotype: protein_coding
description:
  SecA cross-linking domain protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.


ensembl_gene_id: HMPREF0299_6364
symbol: EFM48695.1
gene_biotype: protein_coding
description:
  Identified by match to protein family HMM PF00571; match to protein family HMM PF01595; match to protein family HMM PF03471.


ensembl_gene_id: HMPREF0299_6365
symbol: gnd
gene_biotype: protein_coding
description:
  Phosphogluconate dehydrogenase (decarboxylating); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.


ensembl_gene_id: HMPREF0299_6367
symbol: EFM49171.1
gene_biotype: protein_coding
description:
  Site-specific recombinase, phage integrase family; Identified by match to protein family HMM PF00589; Belongs to the 'phage' integrase family.


ensembl_gene_id: HMPREF0299_6369
symbol: corA
gene_biotype: protein_coding
description:
  Putative magnesium and cobalt transport protein CorA; Mediates influx of magnesium ions. Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.


ensembl_gene_id: HMPREF0299_6371
symbol: EFM48875.1
gene_biotype: protein_coding
description:
  Pyridine nucleotide-disulfide oxidoreductase; Identified by match to protein family HMM PF00070; match to protein family HMM PF07992.


ensembl_gene_id: HMPREF0299_6377
symbol: EFM48504.1
gene_biotype: protein_coding
description:
  YceI-like domain protein; Identified by match to protein family HMM PF04264; Belongs to the UPF0312 family.


ensembl_gene_id: HMPREF0299_6379
symbol: rbpA
gene_biotype: protein_coding
description:
  Hypothetical protein; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters. Belongs to the RNA polymerase-binding protein RbpA family.


ensembl_gene_id: HMPREF0299_6381
symbol: lnt
gene_biotype: protein_coding
description:
  Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily.


ensembl_gene_id: HMPREF0299_6383
symbol: cobN
gene_biotype: protein_coding
description:
  Cobaltochelatase, CobN subunit; Identified by match to protein family HMM PF02514; match to protein family HMM TIGR02257.


ensembl_gene_id: HMPREF0299_6386
symbol: cobI
gene_biotype: protein_coding
description:
  Precorrin-2 C(20)-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR01466; match to protein family HMM TIGR01467.


ensembl_gene_id: HMPREF0299_6388
symbol: cobK
gene_biotype: protein_coding
description:
  precorrin-6A reductase; Identified by match to protein family HMM PF02571; match to protein family HMM TIGR00715.


ensembl_gene_id: HMPREF0299_6389
symbol: cobM
gene_biotype: protein_coding
description:
  Precorrin-4 C(11)-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR01465.


ensembl_gene_id: HMPREF0299_6390
symbol: cbiE
gene_biotype: protein_coding
description:
  Precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR02467; match to protein family HMM TIGR02469.


ensembl_gene_id: HMPREF0299_6392
symbol: EFM48669.1
gene_biotype: protein_coding
description:
  Peptidase, M24 family; Identified by match to protein family HMM PF00557; Belongs to the peptidase M24B family.


ensembl_gene_id: HMPREF0299_6393
symbol: EFM49006.1
gene_biotype: protein_coding
description:
  DEAD/DEAH box helicase; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF04851; match to protein family HMM PF08148.


ensembl_gene_id: HMPREF0299_6394
symbol: tatC
gene_biotype: protein_coding
description:
  Twin arginine-targeting protein translocase TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.


ensembl_gene_id: HMPREF0299_6397
symbol: pafA
gene_biotype: protein_coding
description:
  Proteasome accessory factor PafA; Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side- chain amino group of a substrate lysine.


ensembl_gene_id: HMPREF0299_6398
symbol: pup
gene_biotype: protein_coding
description:
  Ubiquitin-like protein Pup; Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.


ensembl_gene_id: HMPREF0299_6399
symbol: EFM48933.1
gene_biotype: protein_coding
description:
  Proteasome accessory factor PafA2; Identified by match to protein family HMM PF03136; match to protein family HMM PF03316; match to protein family HMM TIGR03688.


ensembl_gene_id: HMPREF0299_6400
symbol: arc
gene_biotype: protein_coding
description:
  Proteasome ATPase; Identified by match to protein family HMM PF00004; match to protein family HMM TIGR03689.


ensembl_gene_id: HMPREF0299_6401
symbol: EFM49199.1
gene_biotype: protein_coding
description:
  tRNA methyltransferase complex GCD14 subunit; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.


ensembl_gene_id: HMPREF0299_6405
symbol: fhs
gene_biotype: protein_coding
description:
  Formate--tetrahydrofolate ligase; Identified by match to protein family HMM PF01268; Belongs to the formate--tetrahydrofolate ligase family.


ensembl_gene_id: HMPREF0299_6406
symbol: aspA
gene_biotype: protein_coding
description:
  Aspartate ammonia-lyase; Identified by match to protein family HMM PF00206; match to protein family HMM TIGR00839.


ensembl_gene_id: HMPREF0299_6407
symbol: hisG
gene_biotype: protein_coding
description:
  ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily.


ensembl_gene_id: HMPREF0299_6408
symbol: hisE
gene_biotype: protein_coding
description:
  phosphoribosyl-ATP diphosphatase; Identified by match to protein family HMM PF01503; match to protein family HMM TIGR03188; Belongs to the PRA-PH family.


ensembl_gene_id: HMPREF0299_6410
symbol: metH
gene_biotype: protein_coding
description:
  5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.


ensembl_gene_id: HMPREF0299_6412
symbol: mshC
gene_biotype: protein_coding
description:
  cysteine--1-D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase; Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins; Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.


ensembl_gene_id: HMPREF0299_6413
symbol: uppP
gene_biotype: protein_coding
description:
  Undecaprenyl-diphosphatase UppP; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.


ensembl_gene_id: HMPREF0299_6415
symbol: pyrD
gene_biotype: protein_coding
description:
  Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.


ensembl_gene_id: HMPREF0299_6428
symbol: EFM49114.1
gene_biotype: protein_coding
description:
  LAO/AO transport system ATPase; Identified by match to protein family HMM PF03308; match to protein family HMM TIGR00750.


ensembl_gene_id: HMPREF0299_6429
symbol: EFM48991.1
gene_biotype: protein_coding
description:
  methylmalonyl-CoA mutase; Identified by match to protein family HMM PF01642; match to protein family HMM PF02310; match to protein family HMM TIGR00640; match to protein family HMM TIGR00641.


ensembl_gene_id: HMPREF0299_6430
symbol: EFM48940.1
gene_biotype: protein_coding
description:
  Putative methylmalonyl-CoA mutase, small subunit; Identified by match to protein family HMM PF01642.


ensembl_gene_id: HMPREF0299_6435
symbol: hemH
gene_biotype: protein_coding
description:
  Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.


ensembl_gene_id: HMPREF0299_6442
symbol: EFM48520.1
gene_biotype: protein_coding
description:
  ACT domain protein; Identified by match to protein family HMM PF01842; Belongs to the UPF0237 family.


ensembl_gene_id: HMPREF0299_6448
symbol: EFM48722.1
gene_biotype: protein_coding
description:
  SUF system FeS assembly protein, NifU family; Identified by match to protein family HMM PF01592; match to protein family HMM TIGR01994.


ensembl_gene_id: HMPREF0299_6449
symbol: sufS
gene_biotype: protein_coding
description:
  Cysteine desulfurase, SufS subfamily; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.


ensembl_gene_id: HMPREF0299_6450
symbol: sufC
gene_biotype: protein_coding
description:
  FeS assembly ATPase SufC; Identified by match to protein family HMM PF00005; match to protein family HMM TIGR01978.


ensembl_gene_id: HMPREF0299_6451
symbol: sufD
gene_biotype: protein_coding
description:
  FeS assembly protein SufD; Identified by match to protein family HMM PF01458; match to protein family HMM TIGR01981.


ensembl_gene_id: HMPREF0299_6452
symbol: sufB
gene_biotype: protein_coding
description:
  FeS assembly protein SufB; Identified by match to protein family HMM PF01458; match to protein family HMM TIGR01980.


ensembl_gene_id: HMPREF0299_6459
symbol: azlD
gene_biotype: protein_coding
description:
  Branched-chain amino acid transport protein (AzlD); Identified by match to protein family HMM PF05437.


ensembl_gene_id: HMPREF0299_6460
symbol: cyoE
gene_biotype: protein_coding
description:
  Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.


ensembl_gene_id: HMPREF0299_6461
symbol: tkt
gene_biotype: protein_coding
description:
  Transketolase; Identified by match to protein family HMM PF00456; match to protein family HMM PF02779; match to protein family HMM PF02780; match to protein family HMM TIGR00232; Belongs to the transketolase family.


ensembl_gene_id: HMPREF0299_6462
symbol: tal
gene_biotype: protein_coding
description:
  Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily.


ensembl_gene_id: HMPREF0299_6463
symbol: zwf
gene_biotype: protein_coding
description:
  Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.


ensembl_gene_id: HMPREF0299_6466
symbol: secG
gene_biotype: protein_coding
description:
  Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.


ensembl_gene_id: HMPREF0299_6467
symbol: ppc
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate carboxykinase (GTP); Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family.


ensembl_gene_id: HMPREF0299_6468
symbol: tpiA
gene_biotype: protein_coding
description:
  Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.


ensembl_gene_id: HMPREF0299_6469
symbol: pgk
gene_biotype: protein_coding
description:
  Phosphoglycerate kinase; Identified by match to protein family HMM PF00162; Belongs to the phosphoglycerate kinase family.


ensembl_gene_id: HMPREF0299_6472
symbol: EFM49093.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family.


ensembl_gene_id: HMPREF0299_6474
symbol: uvrC
gene_biotype: protein_coding
description:
  Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.


ensembl_gene_id: HMPREF0299_6476
symbol: ribE
gene_biotype: protein_coding
description:
  Riboflavin synthase, alpha subunit; Identified by match to protein family HMM PF00677; match to protein family HMM TIGR00187.


ensembl_gene_id: HMPREF0299_6477
symbol: rpe
gene_biotype: protein_coding
description:
  Ribulose-phosphate 3-epimerase; Identified by match to protein family HMM PF00834; match to protein family HMM TIGR01163; Belongs to the ribulose-phosphate 3-epimerase family.


ensembl_gene_id: HMPREF0299_6478
symbol: EFM48853.1
gene_biotype: protein_coding
description:
  Putative ribosomal RNA small subunit methyltransferase B; Identified by match to protein family HMM PF01029; match to protein family HMM PF01189; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.


ensembl_gene_id: HMPREF0299_6479
symbol: fmt
gene_biotype: protein_coding
description:
  methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.


ensembl_gene_id: HMPREF0299_6480
symbol: def
gene_biotype: protein_coding
description:
  Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.


ensembl_gene_id: HMPREF0299_6481
symbol: priA
gene_biotype: protein_coding
description:
  Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.


ensembl_gene_id: HMPREF0299_6482
symbol: metK
gene_biotype: protein_coding
description:
  Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.


ensembl_gene_id: HMPREF0299_6483
symbol: coaBC
gene_biotype: protein_coding
description:
  Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.


ensembl_gene_id: HMPREF0299_6484
symbol: rpoZ
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.


ensembl_gene_id: HMPREF0299_6487
symbol: pyrF
gene_biotype: protein_coding
description:
  Orotidine 5'-phosphate decarboxylase; Identified by match to protein family HMM PF00215; match to protein family HMM TIGR02127; Belongs to the OMP decarboxylase family. Type 2 subfamily.


ensembl_gene_id: HMPREF0299_6488
symbol: carB
gene_biotype: protein_coding
description:
  Carbamoyl-phosphate synthase, large subunit; Identified by match to protein family HMM PF00289; match to protein family HMM PF01071; match to protein family HMM PF02142; match to protein family HMM PF02655; match to protein family HMM PF02786; match to protein family HMM PF02787; match to protein family HMM TIGR01369; Belongs to the CarB family.


ensembl_gene_id: HMPREF0299_6489
symbol: carA
gene_biotype: protein_coding
description:
  Carbamoyl-phosphate synthase, small subunit; Identified by match to protein family HMM PF00117; match to protein family HMM PF00988; match to protein family HMM TIGR01368; Belongs to the CarA family.


ensembl_gene_id: HMPREF0299_6490
symbol: pyrC
gene_biotype: protein_coding
description:
  Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.


ensembl_gene_id: HMPREF0299_6491
symbol: pyrB
gene_biotype: protein_coding
description:
  Aspartate carbamoyltransferase; Identified by match to protein family HMM PF00185; match to protein family HMM PF02729; match to protein family HMM TIGR00670; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.


ensembl_gene_id: HMPREF0299_6492
symbol: pyrR
gene_biotype: protein_coding
description:
  Phosphoribosyl transferase domain protein; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.


ensembl_gene_id: HMPREF0299_6494
symbol: EFM48890.1
gene_biotype: protein_coding
description:
  Identified by match to protein family HMM PF01370; match to protein family HMM PF07993; match to protein family HMM PF08338; match to protein family HMM TIGR01777.


ensembl_gene_id: HMPREF0299_6495
symbol: nusB
gene_biotype: protein_coding
description:
  Transcription antitermination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.


ensembl_gene_id: HMPREF0299_6496
symbol: efp
gene_biotype: protein_coding
description:
  Translation elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.


ensembl_gene_id: HMPREF0299_6498
symbol: aroQ
gene_biotype: protein_coding
description:
  3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.


ensembl_gene_id: HMPREF0299_6499
symbol: aroB
gene_biotype: protein_coding
description:
  3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).


ensembl_gene_id: HMPREF0299_6500
symbol: aroK
gene_biotype: protein_coding
description:
  Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.


ensembl_gene_id: HMPREF0299_6501
symbol: aroC
gene_biotype: protein_coding
description:
  Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.


ensembl_gene_id: HMPREF0299_6503
symbol: aroE
gene_biotype: protein_coding
description:
  Shikimate-5-dehydrogenase; Identified by match to protein family HMM PF01488; match to protein family HMM PF08501; match to protein family HMM TIGR01809.


ensembl_gene_id: HMPREF0299_6506
symbol: mltG
gene_biotype: protein_coding
description:
  YceG family protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.


ensembl_gene_id: HMPREF0299_6507
symbol: EFM49081.1
gene_biotype: protein_coding
description:
  RNAse H domain protein, YqgF family; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family.


ensembl_gene_id: HMPREF0299_6508
symbol: alaS
gene_biotype: protein_coding
description:
  alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.


ensembl_gene_id: HMPREF0299_6509
symbol: EFM48760.1
gene_biotype: protein_coding
description:
  Recombination factor protein RarA; Identified by match to protein family HMM PF00004; match to protein family HMM PF01078; match to protein family HMM PF07728.


ensembl_gene_id: HMPREF0299_6511
symbol: aspS
gene_biotype: protein_coding
description:
  aspartate--tRNA ligase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.


ensembl_gene_id: HMPREF0299_6514
symbol: EFM48881.1
gene_biotype: protein_coding
description:
  YhgE/Pip domain protein; Identified by match to protein family HMM PF01061; match to protein family HMM TIGR03061; match to protein family HMM TIGR03062.


ensembl_gene_id: HMPREF0299_6517
symbol: EFM49163.1
gene_biotype: protein_coding
description:
  L-serine ammonia-lyase; Identified by match to protein family HMM PF03313; match to protein family HMM PF03315; match to protein family HMM TIGR00720; Belongs to the iron-sulfur dependent L-serine dehydratase family.


ensembl_gene_id: HMPREF0299_6520
symbol: hisS
gene_biotype: protein_coding
description:
  histidine--tRNA ligase; Identified by match to protein family HMM PF00587; match to protein family HMM PF03129; match to protein family HMM TIGR00442.


ensembl_gene_id: HMPREF0299_6522
symbol: tpx
gene_biotype: protein_coding
description:
  Redoxin family protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily.


ensembl_gene_id: HMPREF0299_6523
symbol: EFM49231.1
gene_biotype: protein_coding
description:
  Peptidyl-prolyl cis-trans isomerase, cyclophilin-type; Identified by match to protein family HMM PF00160.


ensembl_gene_id: HMPREF0299_6526
symbol: relA
gene_biotype: protein_coding
description:
  RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.


ensembl_gene_id: HMPREF0299_6527
symbol: apt
gene_biotype: protein_coding
description:
  Putative adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.


ensembl_gene_id: HMPREF0299_6530
symbol: secF
gene_biotype: protein_coding
description:
  Export membrane protein SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.


ensembl_gene_id: HMPREF0299_6531
symbol: secD
gene_biotype: protein_coding
description:
  Export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.


ensembl_gene_id: HMPREF0299_6532
symbol: yajC
gene_biotype: protein_coding
description:
  Preprotein translocase, YajC subunit; Identified by match to protein family HMM PF02699; match to protein family HMM TIGR00739.


ensembl_gene_id: HMPREF0299_6533
symbol: ruvB
gene_biotype: protein_coding
description:
  Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.


ensembl_gene_id: HMPREF0299_6534
symbol: ruvA
gene_biotype: protein_coding
description:
  Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.


ensembl_gene_id: HMPREF0299_6535
symbol: ruvC
gene_biotype: protein_coding
description:
  Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.


ensembl_gene_id: HMPREF0299_6536
symbol: EFM49098.1
gene_biotype: protein_coding
description:
  DNA-binding regulatory protein, YebC/PmpR family; Identified by match to protein family HMM PF01709; match to protein family HMM TIGR01033.


ensembl_gene_id: HMPREF0299_6541
symbol: EFM48661.1
gene_biotype: protein_coding
description:
  Lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase; Identified by match to protein family HMM PF03279.


ensembl_gene_id: HMPREF0299_6542
symbol: EFM48800.1
gene_biotype: protein_coding
description:
  CDP-alcohol phosphatidyltransferase; Identified by match to protein family HMM PF01066; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: HMPREF0299_6544
symbol: thrS
gene_biotype: protein_coding
description:
  threonine--tRNA ligase; Identified by match to protein family HMM PF00587; match to protein family HMM PF03129; match to protein family HMM PF07973; match to protein family HMM TIGR00418; Belongs to the class-II aminoacyl-tRNA synthetase family.


ensembl_gene_id: HMPREF0299_6545
symbol: EFM48496.1
gene_biotype: protein_coding
description:
  Putative Tat-translocated enzyme; Identified by match to protein family HMM PF04261; match to protein family HMM TIGR01409; match to protein family HMM TIGR01413.


ensembl_gene_id: HMPREF0299_6557
symbol: msrB
gene_biotype: protein_coding
description:
  methionine-R-sulfoxide reductase; Identified by match to protein family HMM PF01641; match to protein family HMM TIGR00357; Belongs to the MsrB Met sulfoxide reductase family.


ensembl_gene_id: HMPREF0299_6560
symbol: EFM48647.1
gene_biotype: protein_coding
description:
  Putative ribonuclease D; Identified by match to protein family HMM PF00570; match to protein family HMM PF01612.


ensembl_gene_id: HMPREF0299_6561
symbol: EFM48546.1
gene_biotype: protein_coding
description:
  Exonuclease, DNA polymerase III, epsilon subunit family; Identified by match to protein family HMM PF00929; match to protein family HMM TIGR00573.


ensembl_gene_id: HMPREF0299_6565
symbol: dxs
gene_biotype: protein_coding
description:
  1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.


ensembl_gene_id: HMPREF0299_6566
symbol: EFM49119.1
gene_biotype: protein_coding
description:
  TRAM domain protein; Identified by match to protein family HMM PF01938; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.


ensembl_gene_id: HMPREF0299_6569
symbol: dut
gene_biotype: protein_coding
description:
  dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.


ensembl_gene_id: HMPREF0299_6575
symbol: rpoD
gene_biotype: protein_coding
description:
  RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.


ensembl_gene_id: HMPREF0299_6587
symbol: EFM49188.1
gene_biotype: protein_coding
description:
  Methyltransferase small domain protein; Identified by match to protein family HMM PF05175; Belongs to the methyltransferase superfamily.


ensembl_gene_id: HMPREF0299_6588
symbol: dtd
gene_biotype: protein_coding
description:
  D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family.


ensembl_gene_id: HMPREF0299_6589
symbol: EFM48705.1
gene_biotype: protein_coding
description:
  RNA polymerase sigma factor SigB; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.


ensembl_gene_id: HMPREF0299_6590
symbol: dtxR
gene_biotype: protein_coding
description:
  Diphtheria toxin repressor; Identified by match to protein family HMM PF01325; match to protein family HMM PF02742.


ensembl_gene_id: HMPREF0299_6591
symbol: galE-2
gene_biotype: protein_coding
description:
  UDP-glucose 4-epimerase; Identified by match to protein family HMM PF00106; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993; match to protein family HMM TIGR01179; Belongs to the NAD(P)-dependent epimerase/dehydratase family.


ensembl_gene_id: HMPREF0299_6596
symbol: EFM48795.1
gene_biotype: protein_coding
description:
  DEAD/DEAH box helicase; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271.


ensembl_gene_id: HMPREF0299_6597
symbol: EFM48838.1
gene_biotype: protein_coding
description:
  LysR substrate binding domain protein; Identified by match to protein family HMM PF00126; match to protein family HMM PF03466; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: HMPREF0299_6600
symbol: hrpA
gene_biotype: protein_coding
description:
  ATP-dependent helicase HrpA; Identified by match to protein family HMM PF00271; match to protein family HMM PF04408; match to protein family HMM PF07717; match to protein family HMM TIGR01967.


ensembl_gene_id: HMPREF0299_6601
symbol: nrdR
gene_biotype: protein_coding
description:
  Transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.


ensembl_gene_id: HMPREF0299_6603
symbol: lexA
gene_biotype: protein_coding
description:
  Repressor LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.


ensembl_gene_id: HMPREF0299_6604
symbol: EFM48923.1
gene_biotype: protein_coding
description:
  Transcriptional regulator, DeoR family; Identified by match to protein family HMM PF00455; match to protein family HMM PF08220.


ensembl_gene_id: HMPREF0299_6605
symbol: ptsP
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).


ensembl_gene_id: HMPREF0299_6607
symbol: EFM48583.1
gene_biotype: protein_coding
description:
  Transcriptional regulator, DeoR family; Identified by match to protein family HMM PF00455; match to protein family HMM PF08220; match to protein family HMM PF08279.


ensembl_gene_id: HMPREF0299_6608
symbol: pfkB
gene_biotype: protein_coding
description:
  1-phosphofructokinase; Identified by match to protein family HMM PF00294; match to protein family HMM TIGR03168; match to protein family HMM TIGR03828; Belongs to the carbohydrate kinase PfkB family.


ensembl_gene_id: HMPREF0299_6609
symbol: EFM48457.1
gene_biotype: protein_coding
description:
  Phosphotransferase system, EIIC; Identified by match to protein family HMM PF00359; match to protein family HMM PF02378; match to protein family HMM PF02379; match to protein family HMM TIGR00829; match to protein family HMM TIGR00848; match to protein family HMM TIGR01427.


ensembl_gene_id: HMPREF0299_6610
symbol: EFM49227.1
gene_biotype: protein_coding
description:
  Phosphocarrier, HPr family; Identified by match to protein family HMM PF00381; match to protein family HMM TIGR01003.


ensembl_gene_id: HMPREF0299_6611
symbol: hutI
gene_biotype: protein_coding
description:
  Imidazolonepropionase; Identified by match to protein family HMM PF01979; match to protein family HMM PF07969; match to protein family HMM TIGR01224.


ensembl_gene_id: HMPREF0299_6614
symbol: hutH
gene_biotype: protein_coding
description:
  Histidine ammonia-lyase; Identified by match to protein family HMM PF00221; match to protein family HMM TIGR01225.


ensembl_gene_id: HMPREF0299_6615
symbol: EFM49127.1
gene_biotype: protein_coding
description:
  IclR helix-turn-helix domain protein; Identified by match to protein family HMM PF01614; match to protein family HMM PF09339.


ensembl_gene_id: HMPREF0299_6616
symbol: hutG
gene_biotype: protein_coding
description:
  Formimidoylglutamase; Catalyzes the conversion of N-formimidoyl-L-glutamate to L- glutamate and formamide; Belongs to the arginase family.


ensembl_gene_id: HMPREF0299_6617
symbol: EFM48757.1
gene_biotype: protein_coding
description:
  Putative permease; Identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801.


ensembl_gene_id: HMPREF0299_6618
symbol: hflX
gene_biotype: protein_coding
description:
  GTP-binding protein HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.


ensembl_gene_id: HMPREF0299_6623
symbol: dapF
gene_biotype: protein_coding
description:
  Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.


ensembl_gene_id: HMPREF0299_6624
symbol: miaA
gene_biotype: protein_coding
description:
  tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.


ensembl_gene_id: HMPREF0299_6628
symbol: miaB
gene_biotype: protein_coding
description:
  tRNA-i(6)A37 thiotransferase enzyme MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.


ensembl_gene_id: HMPREF0299_6630
symbol: recA
gene_biotype: protein_coding
description:
  RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.


ensembl_gene_id: HMPREF0299_6637
symbol: EFM48809.1
gene_biotype: protein_coding
description:
  Drug resistance transporter, Bcr/CflA subfamily; Identified by match to protein family HMM PF07690; match to protein family HMM TIGR00710.


ensembl_gene_id: HMPREF0299_6640
symbol: EFM48608.1
gene_biotype: protein_coding
description:
  Competence/damage-inducible domain protein CinA; Identified by match to protein family HMM PF02464; match to protein family HMM TIGR00199; Belongs to the CinA family.


ensembl_gene_id: HMPREF0299_6641
symbol: pgsA
gene_biotype: protein_coding
description:
  CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Identified by match to protein family HMM PF01066; match to protein family HMM TIGR00560; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: HMPREF0299_6643
symbol: EFM48625.1
gene_biotype: protein_coding
description:
  Integral membrane protein, TerC family; Identified by match to protein family HMM PF03741; match to protein family HMM TIGR03718.


ensembl_gene_id: HMPREF0299_6646
symbol: rnj
gene_biotype: protein_coding
description:
  Hypothetical protein; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.


ensembl_gene_id: HMPREF0299_6647
symbol: dapA
gene_biotype: protein_coding
description:
  Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).


ensembl_gene_id: HMPREF0299_6648
symbol: thyX
gene_biotype: protein_coding
description:
  Thymidylate synthase, flavin-dependent; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.


ensembl_gene_id: HMPREF0299_6649
symbol: dapB
gene_biotype: protein_coding
description:
  Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.


ensembl_gene_id: HMPREF0299_6650
symbol: gpsI
gene_biotype: protein_coding
description:
  Guanosine pentaphosphate synthetase I/polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.


ensembl_gene_id: HMPREF0299_6651
symbol: rpsO
gene_biotype: protein_coding
description:
  Ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.


ensembl_gene_id: HMPREF0299_6653
symbol: ribF
gene_biotype: protein_coding
description:
  Riboflavin biosynthesis protein RibF; Identified by match to protein family HMM PF01687; match to protein family HMM PF06574; match to protein family HMM TIGR00083; Belongs to the ribF family.


ensembl_gene_id: HMPREF0299_6654
symbol: truB
gene_biotype: protein_coding
description:
  tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.


ensembl_gene_id: HMPREF0299_6658
symbol: EFM49086.1
gene_biotype: protein_coding
description:
  DHHA1 domain protein; Identified by match to protein family HMM PF01368; match to protein family HMM PF02272.


ensembl_gene_id: HMPREF0299_6659
symbol: rbfA
gene_biotype: protein_coding
description:
  Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.


ensembl_gene_id: HMPREF0299_6660
symbol: infB
gene_biotype: protein_coding
description:
  Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.


ensembl_gene_id: HMPREF0299_6661
symbol: nusA
gene_biotype: protein_coding
description:
  Transcription termination factor NusA; Participates in both transcription termination and antitermination.


ensembl_gene_id: HMPREF0299_6662
symbol: rimP
gene_biotype: protein_coding
description:
  Hypothetical protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.


ensembl_gene_id: HMPREF0299_6664
symbol: proS
gene_biotype: protein_coding
description:
  proline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacy [...]


ensembl_gene_id: HMPREF0299_6668
symbol: cobA
gene_biotype: protein_coding
description:
  uroporphyrinogen-III C-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR01469; Belongs to the precorrin methyltransferase family.


ensembl_gene_id: HMPREF0299_6669
symbol: EFM48976.1
gene_biotype: protein_coding
description:
  6-O-methylguanine DNA methyltransferase, DNA binding domain protein; Identified by match to protein family HMM PF01035; match to protein family HMM TIGR00589.


ensembl_gene_id: HMPREF0299_6670
symbol: cobB
gene_biotype: protein_coding
description:
  Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.


ensembl_gene_id: HMPREF0299_6673
symbol: cobO
gene_biotype: protein_coding
description:
  cob(I)yrinic acid a,c-diamide adenosyltransferase; Identified by match to protein family HMM PF02572; match to protein family HMM TIGR00708.


ensembl_gene_id: HMPREF0299_6675
symbol: EFM48555.1
gene_biotype: protein_coding
description:
  ATPase family associated with various cellular activities (AAA); An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF01078; match to protein family HMM PF07726; match to protein family HMM PF07728.


ensembl_gene_id: HMPREF0299_6676
symbol: mqo
gene_biotype: protein_coding
description:
  Malate dehydrogenase (quinone); Identified by match to protein family HMM PF01266; match to protein family HMM PF06039; match to protein family HMM TIGR01320.


ensembl_gene_id: HMPREF0299_6679
symbol: mtr
gene_biotype: protein_coding
description:
  Mycothione reductase; Identified by match to protein family HMM PF00070; match to protein family HMM PF02852; match to protein family HMM PF07992; match to protein family HMM TIGR03452.


ensembl_gene_id: HMPREF0299_6681
symbol: cobQ
gene_biotype: protein_coding
description:
  Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.


ensembl_gene_id: HMPREF0299_6684
symbol: EFM48646.1
gene_biotype: protein_coding
description:
  Penicillin-binding protein, transpeptidase domain protein; Identified by match to protein family HMM PF00905; match to protein family HMM PF05223.


ensembl_gene_id: HMPREF0299_6685
symbol: ispG
gene_biotype: protein_coding
description:
  4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family.


ensembl_gene_id: HMPREF0299_6691
symbol: EFM48985.1
gene_biotype: protein_coding
description:
  ABC transporter, ATP-binding protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF00005.


ensembl_gene_id: HMPREF0299_6697
symbol: dxr
gene_biotype: protein_coding
description:
  1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family.


ensembl_gene_id: HMPREF0299_6700
symbol: rlmN
gene_biotype: protein_coding
description:
  23S rRNA m2A2503 methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family.


ensembl_gene_id: HMPREF0299_6703
symbol: frr
gene_biotype: protein_coding
description:
  Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.


ensembl_gene_id: HMPREF0299_6705
symbol: tsf
gene_biotype: protein_coding
description:
  Translation elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.


ensembl_gene_id: HMPREF0299_6706
symbol: rpsB
gene_biotype: protein_coding
description:
  Ribosomal protein S2; Identified by match to protein family HMM PF00318; match to protein family HMM TIGR01011; Belongs to the universal ribosomal protein uS2 family.


ensembl_gene_id: HMPREF0299_6709
symbol: xerC
gene_biotype: protein_coding
description:
  Site-specific tyrosine recombinase XerC; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.


ensembl_gene_id: HMPREF0299_6710
symbol: dprA
gene_biotype: protein_coding
description:
  DNA protecting protein DprA; Identified by match to protein family HMM PF02481; match to protein family HMM TIGR00732.


ensembl_gene_id: HMPREF0299_6711
symbol: EFM48530.1
gene_biotype: protein_coding
description:
  Mg chelatase-like protein; Identified by match to protein family HMM PF01078; match to protein family HMM TIGR00368.


ensembl_gene_id: HMPREF0299_6712
symbol: EFM48537.1
gene_biotype: protein_coding
description:
  Identified by match to protein family HMM PF02021; match to protein family HMM TIGR00252; Belongs to the UPF0102 family.


ensembl_gene_id: HMPREF0299_6715
symbol: lepB
gene_biotype: protein_coding
description:
  Signal peptidase I; Identified by match to protein family HMM PF00717; match to protein family HMM TIGR02227; Belongs to the peptidase S26 family.


ensembl_gene_id: HMPREF0299_6717
symbol: rplS
gene_biotype: protein_coding
description:
  Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.


ensembl_gene_id: HMPREF0299_6719
symbol: EFM48564.1
gene_biotype: protein_coding
description:
  Tex-like protein N-terminal domain protein; Identified by match to protein family HMM PF00575; match to protein family HMM PF09371.


ensembl_gene_id: HMPREF0299_6729
symbol: trmD
gene_biotype: protein_coding
description:
  tRNA (guanine-N(1)-)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.


ensembl_gene_id: HMPREF0299_6730
symbol: rimM
gene_biotype: protein_coding
description:
  16S rRNA processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family.


ensembl_gene_id: HMPREF0299_6732
symbol: rpsP
gene_biotype: protein_coding
description:
  Ribosomal protein S16; Identified by match to protein family HMM PF00886; match to protein family HMM TIGR00002; Belongs to the bacterial ribosomal protein bS16 family.


ensembl_gene_id: HMPREF0299_6733
symbol: EFM48455.1
gene_biotype: protein_coding
description:
  Putative calcium-translocating P-type ATPase, PMCA-type; Identified by match to protein family HMM PF00122; match to protein family HMM PF00689; match to protein family HMM PF00690; match to protein family HMM PF00702; match to protein family HMM TIGR01494.


ensembl_gene_id: HMPREF0299_6734
symbol: ffh
gene_biotype: protein_coding
description:
  Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.


ensembl_gene_id: HMPREF0299_6735
symbol: EFM48702.1
gene_biotype: protein_coding
description:
  Putative protein-P-II uridylyltransferase; Identified by match to protein family HMM PF01909; match to protein family HMM PF01966; match to protein family HMM PF08335.


ensembl_gene_id: HMPREF0299_6736
symbol: rnz
gene_biotype: protein_coding
description:
  Ribonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family.


ensembl_gene_id: HMPREF0299_6737
symbol: EFM48915.1
gene_biotype: protein_coding
description:
  Nitrogen regulatory protein P-II; Identified by match to protein family HMM PF00543; Belongs to the P(II) protein family.


ensembl_gene_id: HMPREF0299_6738
symbol: ftsY
gene_biotype: protein_coding
description:
  Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).


ensembl_gene_id: HMPREF0299_6742
symbol: EFM48792.1
gene_biotype: protein_coding
description:
  BAAT/acyl-CoA thioester hydrolase C-terminal domain protein; Identified by match to protein family HMM PF08840.


ensembl_gene_id: HMPREF0299_6745
symbol: smc
gene_biotype: protein_coding
description:
  Chromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family.


ensembl_gene_id: HMPREF0299_6749
symbol: EFM48732.1
gene_biotype: protein_coding
description:
  Macro domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF01661.


ensembl_gene_id: HMPREF0299_6755
symbol: EFM48617.1
gene_biotype: protein_coding
description:
  Putative ATP synthase F0, A subunit; Identified by match to protein family HMM PF01235; match to protein family HMM TIGR00835.


ensembl_gene_id: HMPREF0299_6756
symbol: mutM
gene_biotype: protein_coding
description:
  DNA-formamidopyrimidine glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.


ensembl_gene_id: HMPREF0299_6757
symbol: rnc
gene_biotype: protein_coding
description:
  Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.


ensembl_gene_id: HMPREF0299_6760
symbol: EFM48643.1
gene_biotype: protein_coding
description:
  Glu/Leu/Phe/Val dehydrogenase, dimerization domain protein; Identified by match to protein family HMM PF00208; match to protein family HMM PF02812; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.


ensembl_gene_id: HMPREF0299_6761
symbol: EFM49228.1
gene_biotype: protein_coding
description:
  Glycerate kinase; Identified by match to protein family HMM PF02595; match to protein family HMM TIGR00045; Belongs to the glycerate kinase type-1 family.


ensembl_gene_id: HMPREF0299_6765
symbol: budA
gene_biotype: protein_coding
description:
  Alpha-acetolactate decarboxylase; Identified by match to protein family HMM PF03306; match to protein family HMM TIGR01252; Belongs to the alpha-acetolactate decarboxylase family.


ensembl_gene_id: HMPREF0299_6767
symbol: glgP
gene_biotype: protein_coding
description:
  Phosphorylase, glycogen/starch/alpha-glucan family; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.


ensembl_gene_id: HMPREF0299_6768
symbol: pyk
gene_biotype: protein_coding
description:
  Pyruvate kinase; Identified by match to protein family HMM PF00224; match to protein family HMM PF02887; match to protein family HMM TIGR01064; Belongs to the pyruvate kinase family.


ensembl_gene_id: HMPREF0299_6769
symbol: lgt
gene_biotype: protein_coding
description:
  Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.


ensembl_gene_id: HMPREF0299_6771
symbol: EFM49178.1
gene_biotype: protein_coding
description:
  Trp region conserved hypothetical membrane protein; Identified by match to protein family HMM PF09534; match to protein family HMM TIGR02234.


ensembl_gene_id: HMPREF0299_6772
symbol: hisI
gene_biotype: protein_coding
description:
  phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.


ensembl_gene_id: HMPREF0299_6773
symbol: hisF
gene_biotype: protein_coding
description:
  Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.


ensembl_gene_id: HMPREF0299_6775
symbol: hisA
gene_biotype: protein_coding
description:
  Bifunctional HisA/TrpF protein; Identified by match to protein family HMM PF00977; match to protein family HMM TIGR01919.


ensembl_gene_id: HMPREF0299_6776
symbol: hisH
gene_biotype: protein_coding
description:
  Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.


ensembl_gene_id: HMPREF0299_6780
symbol: hisC-2
gene_biotype: protein_coding
description:
  Histidinol-phosphate transaminase; Identified by match to protein family HMM PF00155; match to protein family HMM TIGR01141; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.


ensembl_gene_id: HMPREF0299_6781
symbol: hisD
gene_biotype: protein_coding
description:
  Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.


ensembl_gene_id: HMPREF0299_6785
symbol: EFM49048.1
gene_biotype: protein_coding
description:
  Transcriptional regulator, TetR family; Identified by match to protein family HMM PF00440; match to protein family HMM PF02909.


ensembl_gene_id: HMPREF0299_6786
symbol: glgX
gene_biotype: protein_coding
description:
  Glycogen debranching enzyme GlgX; Identified by match to protein family HMM PF00128; match to protein family HMM PF02922; match to protein family HMM TIGR02100; Belongs to the glycosyl hydrolase 13 family.


ensembl_gene_id: HMPREF0299_6787
symbol: EFM48901.1
gene_biotype: protein_coding
description:
  Exonuclease, DNA polymerase III, epsilon subunit family; Identified by match to protein family HMM PF00929.


ensembl_gene_id: HMPREF0299_6793
symbol: ilvA
gene_biotype: protein_coding
description:
  Threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.


ensembl_gene_id: HMPREF0299_6797
symbol: EFM48439.1
gene_biotype: protein_coding
description:
  ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005; match to protein family HMM PF02463.


ensembl_gene_id: HMPREF0299_6799
symbol: dnaE
gene_biotype: protein_coding
description:
  DNA polymerase III subunit alpha; Identified by match to protein family HMM PF01336; match to protein family HMM PF02811; match to protein family HMM PF07733; match to protein family HMM TIGR00594.


ensembl_gene_id: HMPREF0299_6800
symbol: rarD
gene_biotype: protein_coding
description:
  Protein RarD; Identified by match to protein family HMM PF00892; match to protein family HMM TIGR00688.


ensembl_gene_id: HMPREF0299_6803
symbol: EFM49205.1
gene_biotype: protein_coding
description:
  Pseudouridine synthase, RluA family; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.


ensembl_gene_id: HMPREF0299_6804
symbol: lspA
gene_biotype: protein_coding
description:
  Signal peptidase II; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.


ensembl_gene_id: HMPREF0299_6810
symbol: dinB
gene_biotype: protein_coding
description:
  ImpB/MucB/SamB family protein; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.


ensembl_gene_id: HMPREF0299_6812
symbol: ileS
gene_biotype: protein_coding
description:
  isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.


ensembl_gene_id: HMPREF0299_6814
symbol: EFM48715.1
gene_biotype: protein_coding
description:
  DivIVA domain protein; Identified by match to protein family HMM PF05103; match to protein family HMM TIGR03544.


ensembl_gene_id: HMPREF0299_6816
symbol: EFM49125.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.


ensembl_gene_id: HMPREF0299_6817
symbol: EFM48960.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein, YfiH family; Identified by match to protein family HMM PF02578; match to protein family HMM TIGR00726; Belongs to the multicopper oxidase YfiH/RL5 family.


ensembl_gene_id: HMPREF0299_6818
symbol: ftsZ
gene_biotype: protein_coding
description:
  Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.


ensembl_gene_id: HMPREF0299_6821
symbol: murG
gene_biotype: protein_coding
description:
  Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.


ensembl_gene_id: HMPREF0299_6823
symbol: ftsW
gene_biotype: protein_coding
description:
  Cell division protein FtsW; Identified by match to protein family HMM PF01098; match to protein family HMM TIGR02614; Belongs to the SEDS family.


ensembl_gene_id: HMPREF0299_6824
symbol: murD
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.


ensembl_gene_id: HMPREF0299_6825
symbol: mraY
gene_biotype: protein_coding
description:
  phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.


ensembl_gene_id: HMPREF0299_6826
symbol: murF
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.


ensembl_gene_id: HMPREF0299_6827
symbol: murE
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.


ensembl_gene_id: HMPREF0299_6828
symbol: EFM48494.1
gene_biotype: protein_coding
description:
  Penicillin-binding protein, transpeptidase domain protein; Identified by match to protein family HMM PF00905; match to protein family HMM PF03717.


ensembl_gene_id: HMPREF0299_6830
symbol: mraW
gene_biotype: protein_coding
description:
  S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.


ensembl_gene_id: HMPREF0299_6836
symbol: metF
gene_biotype: protein_coding
description:
  Methylenetetrahydrofolate reductase (NAD(P)H); Identified by match to protein family HMM PF02219; match to protein family HMM TIGR00676; Belongs to the methylenetetrahydrofolate reductase family.


ensembl_gene_id: HMPREF0299_6838
symbol: EFM49247.1
gene_biotype: protein_coding
description:
  Carotene biosynthesis associated membrane protein; Identified by match to protein family HMM TIGR03459.


ensembl_gene_id: HMPREF0299_6839
symbol: EFM49017.1
gene_biotype: protein_coding
description:
  Kinase domain protein; Identified by match to protein family HMM PF00069; match to protein family HMM PF03793.


ensembl_gene_id: HMPREF0299_6841
symbol: EFM48701.1
gene_biotype: protein_coding
description:
  NAD dependent epimerase/dehydratase family protein; Identified by match to protein family HMM PF01370.


ensembl_gene_id: HMPREF0299_6842
symbol: EFM48774.1
gene_biotype: protein_coding
description:
  3-deoxy-7-phosphoheptulonate synthase; Identified by match to protein family HMM PF01474; match to protein family HMM TIGR01358; Belongs to the class-II DAHP synthase family.


ensembl_gene_id: HMPREF0299_6853
symbol: qcrC
gene_biotype: protein_coding
description:
  Menaquinol-cytochrome c reductase cytochrome c subunit; Identified by match to protein family HMM PF00034.


ensembl_gene_id: HMPREF0299_6856
symbol: EFM48573.1
gene_biotype: protein_coding
description:
  Cytochrome C oxidase subunit II, periplasmic domain protein; Identified by match to protein family HMM PF00116.


ensembl_gene_id: HMPREF0299_6857
symbol: asnB
gene_biotype: protein_coding
description:
  Asparagine synthase (glutamine-hydrolyzing); Identified by match to protein family HMM PF00310; match to protein family HMM PF00733; match to protein family HMM TIGR01536.


ensembl_gene_id: HMPREF0299_6858
symbol: EFM49055.1
gene_biotype: protein_coding
description:
  Iron-sulfur cluster assembly accessory protein; Identified by match to protein family HMM PF01521; match to protein family HMM TIGR00049; Belongs to the HesB/IscA family.


ensembl_gene_id: HMPREF0299_6861
symbol: cobU
gene_biotype: protein_coding
description:
  Adenosylcobinamide kinase/adenosylcobinamidephosphate guanylyltransferase; Identified by match to protein family HMM PF02283.


ensembl_gene_id: HMPREF0299_6862
symbol: cobT
gene_biotype: protein_coding
description:
  Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).


ensembl_gene_id: HMPREF0299_6863
symbol: cobS
gene_biotype: protein_coding
description:
  Cobalamin-5-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.


ensembl_gene_id: HMPREF0299_6864
symbol: ilvE
gene_biotype: protein_coding
description:
  Branched-chain-amino-acid transaminase; Identified by match to protein family HMM PF01063; match to protein family HMM TIGR01123.


ensembl_gene_id: HMPREF0299_6865
symbol: pepA
gene_biotype: protein_coding
description:
  Cytosol aminopeptidase family, catalytic domain protein; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.


ensembl_gene_id: HMPREF0299_6867
symbol: sucB
gene_biotype: protein_coding
description:
  2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; Identified by match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817; match to protein family HMM TIGR02927.


ensembl_gene_id: HMPREF0299_6869
symbol: gcvP
gene_biotype: protein_coding
description:
  Glycine dehydrogenase; Identified by match to protein family HMM PF02347; match to protein family HMM TIGR00461; Belongs to the GcvP family.


ensembl_gene_id: HMPREF0299_6871
symbol: gcvH
gene_biotype: protein_coding
description:
  Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.


ensembl_gene_id: HMPREF0299_6872
symbol: lipB
gene_biotype: protein_coding
description:
  Lipoyl(octanoyl) transferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.


ensembl_gene_id: HMPREF0299_6873
symbol: lipA
gene_biotype: protein_coding
description:
  Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.


ensembl_gene_id: HMPREF0299_6877
symbol: glnA
gene_biotype: protein_coding
description:
  Glutamine synthetase, type I; Identified by match to protein family HMM PF00120; match to protein family HMM PF03951; match to protein family HMM TIGR00653.


ensembl_gene_id: HMPREF0299_6881
symbol: EFM48746.1
gene_biotype: protein_coding
description:
  Identified by match to protein family HMM PF03553; match to protein family HMM PF03600; match to protein family HMM PF06808.


ensembl_gene_id: HMPREF0299_6886
symbol: thrC
gene_biotype: protein_coding
description:
  Threonine synthase; Identified by match to protein family HMM PF00291; match to protein family HMM TIGR00260.


ensembl_gene_id: HMPREF0299_6893
symbol: glnE
gene_biotype: protein_coding
description:
  [glutamate--ammonia-ligase] adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal tra [...]


ensembl_gene_id: HMPREF0299_6894
symbol: EFM48791.1
gene_biotype: protein_coding
description:
  Glutamine synthetase, beta-grasp domain protein; Identified by match to protein family HMM PF00120; match to protein family HMM PF03951; Belongs to the glutamine synthetase family.


ensembl_gene_id: HMPREF0299_6895
symbol: EFM48862.1
gene_biotype: protein_coding
description:
  CHAD domain protein; Identified by match to protein family HMM PF01928; match to protein family HMM PF05235.


ensembl_gene_id: HMPREF0299_6900
symbol: rnhA
gene_biotype: protein_coding
description:
  Ribonuclease HI; Identified by match to protein family HMM PF00075; match to protein family HMM PF00300.


ensembl_gene_id: HMPREF0299_6902
symbol: EFM48660.1
gene_biotype: protein_coding
description:
  Dinuclear metal center protein, YbgI family; Identified by match to protein family HMM PF01784; match to protein family HMM TIGR00486; Belongs to the GTP cyclohydrolase I type 2/NIF3 family.


ensembl_gene_id: HMPREF0299_6904
symbol: EFM49165.1
gene_biotype: protein_coding
description:
  HAD hydrolase, family IA, variant 1; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549.


ensembl_gene_id: HMPREF0299_6905
symbol: EFM49027.1
gene_biotype: protein_coding
description:
  Low molecular weight phosphotyrosine protein phosphatase; Identified by match to protein family HMM PF01451; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.


ensembl_gene_id: HMPREF0299_6909
symbol: cobD
gene_biotype: protein_coding
description:
  Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.


ensembl_gene_id: HMPREF0299_6912
symbol: aceE
gene_biotype: protein_coding
description:
  Pyruvate dehydrogenase (acetyl-transferring), homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


ensembl_gene_id: HMPREF0299_6930
symbol: dnaG
gene_biotype: protein_coding
description:
  DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Belongs to the DnaG primase family.


ensembl_gene_id: HMPREF0299_6938
symbol: EFM49059.1
gene_biotype: protein_coding
description:
  Putative dGTPase; Identified by match to protein family HMM PF01966; match to protein family HMM TIGR01353; Belongs to the dGTPase family. Type 2 subfamily.


ensembl_gene_id: HMPREF0299_6943
symbol: glyS
gene_biotype: protein_coding
description:
  glycine--tRNA ligase; Catalyzes the attachment of glycine to tRNA(Gly). Belongs to the class-II aminoacyl-tRNA synthetase family.


ensembl_gene_id: HMPREF0299_6945
symbol: EFM48421.1
gene_biotype: protein_coding
description:
  Transcriptional regulator, Fur family; Identified by match to protein family HMM PF01475; Belongs to the Fur family.


ensembl_gene_id: HMPREF0299_6949
symbol: era
gene_biotype: protein_coding
description:
  Ribosome biogenesis GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.


ensembl_gene_id: HMPREF0299_6953
symbol: EFM48533.1
gene_biotype: protein_coding
description:
  Pyridoxal kinase; Identified by match to protein family HMM PF08543; match to protein family HMM TIGR00687; Belongs to the pyridoxine kinase family.


ensembl_gene_id: HMPREF0299_6954
symbol: EFM48431.1
gene_biotype: protein_coding
description:
  CBS domain protein; Identified by match to protein family HMM PF00571; match to protein family HMM PF01595.


ensembl_gene_id: HMPREF0299_6955
symbol: ybeY
gene_biotype: protein_coding
description:
  Translation metalloprotein YbeY; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.


ensembl_gene_id: HMPREF0299_6957
symbol: EFM48912.1
gene_biotype: protein_coding
description:
  RNA methyltransferase, RsmE family; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.


ensembl_gene_id: HMPREF0299_6958
symbol: dnaJ-2
gene_biotype: protein_coding
description:
  Putative chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions betwee [...]


ensembl_gene_id: HMPREF0299_6959
symbol: hrcA
gene_biotype: protein_coding
description:
  Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons.


ensembl_gene_id: HMPREF0299_6960
symbol: EFM49071.1
gene_biotype: protein_coding
description:
  Putative oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.


ensembl_gene_id: HMPREF0299_6964
symbol: malQ
gene_biotype: protein_coding
description:
  4-alpha-glucanotransferase; Identified by match to protein family HMM PF02446; match to protein family HMM TIGR00217.


ensembl_gene_id: HMPREF0299_6984
symbol: idi
gene_biotype: protein_coding
description:
  Isopentenyl-diphosphate delta-isomerase; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).


ensembl_gene_id: HMPREF0299_6987
symbol: brnQ
gene_biotype: protein_coding
description:
  Branched-chain amino acid transport system II carrier protein; Component of the transport system for branched-chain amino acids.


ensembl_gene_id: HMPREF0299_6992
symbol: EFM48622.1
gene_biotype: protein_coding
description:
  Putative phosphonate C-P lyase system protein PhnK; Identified by match to protein family HMM PF00005; Belongs to the ABC transporter superfamily.


ensembl_gene_id: HMPREF0299_6995
symbol: EFM48765.1
gene_biotype: protein_coding
description:
  Pyridoxal phosphate enzyme, YggS family; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.


ensembl_gene_id: HMPREF0299_6997
symbol: EFM48865.1
gene_biotype: protein_coding
description:
  Transporter, auxin efflux carrier (AEC) family protein; Identified by match to protein family HMM PF03547.


ensembl_gene_id: HMPREF0299_7010
symbol: lepA
gene_biotype: protein_coding
description:
  GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.


ensembl_gene_id: HMPREF0299_7017
symbol: holA
gene_biotype: protein_coding
description:
  DNA polymerase III, delta subunit; Identified by match to protein family HMM PF06144; match to protein family HMM TIGR01128.


ensembl_gene_id: HMPREF0299_7019
symbol: EFM48911.1
gene_biotype: protein_coding
description:
  comEA protein; Identified by match to protein family HMM PF00633; match to protein family HMM TIGR00426.


ensembl_gene_id: HMPREF0299_7020
symbol: EFM48751.1
gene_biotype: protein_coding
description:
  EDD domain protein, DegV family; Identified by match to protein family HMM PF02645; match to protein family HMM TIGR00762.


ensembl_gene_id: HMPREF0299_7022
symbol: rsfS
gene_biotype: protein_coding
description:
  Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.


ensembl_gene_id: HMPREF0299_7023
symbol: nadD
gene_biotype: protein_coding
description:
  Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).


ensembl_gene_id: HMPREF0299_7024
symbol: proA
gene_biotype: protein_coding
description:
  Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.


ensembl_gene_id: HMPREF0299_7025
symbol: proB
gene_biotype: protein_coding
description:
  Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.


ensembl_gene_id: HMPREF0299_7026
symbol: cgtA
gene_biotype: protein_coding
description:
  Obg family GTPase CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.


ensembl_gene_id: HMPREF0299_7037
symbol: rpmA
gene_biotype: protein_coding
description:
  Ribosomal protein L27; Identified by match to protein family HMM PF01016; match to protein family HMM TIGR00062; Belongs to the bacterial ribosomal protein bL27 family.


ensembl_gene_id: HMPREF0299_7038
symbol: rplU
gene_biotype: protein_coding
description:
  Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.


ensembl_gene_id: HMPREF0299_7039
symbol: EFM48844.1
gene_biotype: protein_coding
description:
  S1 RNA binding domain protein; Identified by match to protein family HMM PF00575; match to protein family HMM TIGR00757.


ensembl_gene_id: HMPREF0299_7041
symbol: EFM48861.1
gene_biotype: protein_coding
description:
  ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; Identified by match to protein family HMM PF02518; match to protein family HMM PF07730.


ensembl_gene_id: HMPREF0299_7043
symbol: ndk
gene_biotype: protein_coding
description:
  Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.


ensembl_gene_id: HMPREF0299_7045
symbol: folC
gene_biotype: protein_coding
description:
  Bifunctional protein FolC; Identified by match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01499.


ensembl_gene_id: HMPREF0299_7046
symbol: valS
gene_biotype: protein_coding
description:
  valine--tRNA ligase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.


ensembl_gene_id: HMPREF0299_7047
symbol: mdh
gene_biotype: protein_coding
description:
  Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.


ensembl_gene_id: HMPREF0299_7049
symbol: clpX
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.


ensembl_gene_id: HMPREF0299_7050
symbol: clpP
gene_biotype: protein_coding
description:
  Endopeptidase Clp; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.


ensembl_gene_id: HMPREF0299_7052
symbol: tig
gene_biotype: protein_coding
description:
  Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.


ensembl_gene_id: HMPREF0299_7063
symbol: EFM48470.1
gene_biotype: protein_coding
description:
  Ribose 5-phosphate isomerase; Identified by match to protein family HMM PF02502; match to protein family HMM TIGR00689; match to protein family HMM TIGR02133.


ensembl_gene_id: HMPREF0299_7065
symbol: pepN
gene_biotype: protein_coding
description:
  Membrane alanyl aminopeptidase; Identified by match to protein family HMM PF01433; match to protein family HMM TIGR02412.


ensembl_gene_id: HMPREF0299_7067
symbol: metC
gene_biotype: protein_coding
description:
  Cys/Met metabolism PLP-dependent enzyme; Identified by match to protein family HMM PF01053; match to protein family HMM PF01212.


ensembl_gene_id: HMPREF0299_7070
symbol: EFM49151.1
gene_biotype: protein_coding
description:
  ATP-binding cassette protein, ChvD family; Identified by match to protein family HMM PF00005; match to protein family HMM TIGR03719.


ensembl_gene_id: HMPREF0299_7072
symbol: EFM48689.1
gene_biotype: protein_coding
description:
  cytoChrome c oxidase Caa3 assembly factor; Identified by match to protein family HMM PF05425; match to protein family HMM PF09678.


ensembl_gene_id: HMPREF0299_7084
symbol: orn
gene_biotype: protein_coding
description:
  Exonuclease; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family.


ensembl_gene_id: HMPREF0299_7092
symbol: cadA
gene_biotype: protein_coding
description:
  Cadmium-exporting ATPase; Identified by match to protein family HMM PF00122; match to protein family HMM PF00702; match to protein family HMM TIGR01494; match to protein family HMM TIGR01512; match to protein family HMM TIGR01525.


ensembl_gene_id: HMPREF0299_7101
symbol: acpS
gene_biotype: protein_coding
description:
  Putative holo-[acyl-carrier-protein] synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.


ensembl_gene_id: HMPREF0299_7119
symbol: EFM48482.1
gene_biotype: protein_coding
description:
  N-acetylglucosaminylphosphatidylinositol deacetylase; Identified by match to protein family HMM PF02585.


ensembl_gene_id: HMPREF0299_7121
symbol: EFM48687.1
gene_biotype: protein_coding
description:
  ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; Identified by match to protein family HMM PF02518.


ensembl_gene_id: HMPREF0299_7133
symbol: rdgB
gene_biotype: protein_coding
description:
  Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.


ensembl_gene_id: HMPREF0299_7134
symbol: rph
gene_biotype: protein_coding
description:
  tRNA nucleotidyltransferase; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.


ensembl_gene_id: HMPREF0299_7138
symbol: glmS
gene_biotype: protein_coding
description:
  Glutamine-fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.


ensembl_gene_id: HMPREF0299_7142
symbol: clpS
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease adaptor protein ClpS; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family.


ensembl_gene_id: HMPREF0299_7144
symbol: pncB
gene_biotype: protein_coding
description:
  Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.


ensembl_gene_id: HMPREF0299_7147
symbol: serB
gene_biotype: protein_coding
description:
  Phosphoserine phosphatase SerB; Identified by match to protein family HMM PF00702; match to protein family HMM PF01842; match to protein family HMM PF08282; match to protein family HMM TIGR00338; match to protein family HMM TIGR01488.


ensembl_gene_id: HMPREF0299_7148
symbol: ctaD
gene_biotype: protein_coding
description:
  Cytochrome c oxidase, subunit 1; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.


ensembl_gene_id: HMPREF0299_7149
symbol: EFM48896.1
gene_biotype: protein_coding
description:
  Ribonucleoside-diphosphate reductase, beta subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.


ensembl_gene_id: HMPREF0299_7152
symbol: EFM48631.1
gene_biotype: protein_coding
description:
  Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.


ensembl_gene_id: HMPREF0299_7154
symbol: EFM48402.1
gene_biotype: protein_coding
description:
  Glutaredoxin; Identified by match to protein family HMM PF00462; match to protein family HMM TIGR02194.


ensembl_gene_id: HMPREF0299_7155
symbol: rpmJ
gene_biotype: protein_coding
description:
  Ribosomal protein L36; Identified by match to protein family HMM PF00444; match to protein family HMM TIGR01022; Belongs to the bacterial ribosomal protein bL36 family.


ensembl_gene_id: HMPREF0299_7156
symbol: nadE
gene_biotype: protein_coding
description:
  NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family.


ensembl_gene_id: HMPREF0299_7157
symbol: EFM48918.1
gene_biotype: protein_coding
description:
  Fructosamine kinase; Identified by match to protein family HMM PF03881; Belongs to the fructosamine kinase family.


ensembl_gene_id: HMPREF0299_7162
symbol: EFM49056.1
gene_biotype: protein_coding
description:
  ATP synthase, delta/epsilon subunit, beta-sandwich domain protein; Identified by match to protein family HMM PF02823.


ensembl_gene_id: HMPREF0299_7177
symbol: EFM48575.1
gene_biotype: protein_coding
description:
  Helicase C-terminal domain protein; Identified by match to protein family HMM PF00176; match to protein family HMM PF00271; match to protein family HMM PF04851.


ensembl_gene_id: HMPREF0299_7189
symbol: EFM49062.1
gene_biotype: protein_coding
description:
  Na+/H+ antiporter; Identified by match to protein family HMM PF00999; match to protein family HMM TIGR00831.


ensembl_gene_id: HMPREF0299_7195
symbol: pgm
gene_biotype: protein_coding
description:
  Phosphoglucomutase, alpha-D-glucose phosphate-specific; Identified by match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880; match to protein family HMM TIGR01132.


ensembl_gene_id: HMPREF0299_7196
symbol: EFM49089.1
gene_biotype: protein_coding
description:
  CrcB-like protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity.


ensembl_gene_id: HMPREF0299_7197
symbol: crcB
gene_biotype: protein_coding
description:
  CrcB-like protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.


ensembl_gene_id: HMPREF0299_7203
symbol: EFM48610.1
gene_biotype: protein_coding
description:
  Transcriptional regulator, MerR family; Identified by match to protein family HMM PF00376; match to protein family HMM PF09278.


ensembl_gene_id: HMPREF0299_7213
symbol: EFM49508.1
gene_biotype: protein_coding
description:
  Putative inner membrane protein translocase component YidC; Identified by match to protein family HMM PF02096; match to protein family HMM TIGR03592.


ensembl_gene_id: HMPREF0299_7223
symbol: msrA
gene_biotype: protein_coding
description:
  Peptide-methionine (S)-S-oxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.


ensembl_gene_id: HMPREF0299_7224
symbol: sodA
gene_biotype: protein_coding
description:
  Superoxide dismutase, Mn/Fe family; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.


ensembl_gene_id: HMPREF0299_7233
symbol: EFM49593.1
gene_biotype: protein_coding
description:
  Transglycosylase; Identified by match to protein family HMM PF00905; match to protein family HMM PF00912; match to protein family HMM PF03793.


ensembl_gene_id: HMPREF0299_7234
symbol: whiB
gene_biotype: protein_coding
description:
  Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.


ensembl_gene_id: HMPREF0299_7238
symbol: EFM49393.1
gene_biotype: protein_coding
description:
  Cyclic nucleotide-binding domain protein; Identified by match to protein family HMM PF00027; match to protein family HMM PF00325.


ensembl_gene_id: HMPREF0299_7246
symbol: EFM49614.1
gene_biotype: protein_coding
description:
  HAD hydrolase, family IB; Identified by match to protein family HMM TIGR01488; match to protein family HMM TIGR01490.


ensembl_gene_id: HMPREF0299_7249
symbol: EFM49458.1
gene_biotype: protein_coding
description:
  Helicase/secretion neighborhood ATPase; Identified by match to protein family HMM PF00437; match to protein family HMM TIGR03819.


ensembl_gene_id: HMPREF0299_7250
symbol: EFM49265.1
gene_biotype: protein_coding
description:
  Bacterial type II secretion system domain protein F; Identified by match to protein family HMM PF00482.


ensembl_gene_id: HMPREF0299_7255
symbol: EFM49578.1
gene_biotype: protein_coding
description:
  Putative DEAH-box helicase; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF09369; match to protein family HMM TIGR03817.


ensembl_gene_id: HMPREF0299_7257
symbol: topA
gene_biotype: protein_coding
description:
  DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]


ensembl_gene_id: HMPREF0299_7262
symbol: EFM49283.1
gene_biotype: protein_coding
description:
  RNA polymerase sigma factor SigK; Identified by match to protein family HMM PF04542; match to protein family HMM PF04545; match to protein family HMM PF08281; match to protein family HMM TIGR02937; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: HMPREF0299_7264
symbol: EFM49482.1
gene_biotype: protein_coding
description:
  Tat pathway signal sequence domain protein; Identified by match to protein family HMM PF02683; match to protein family HMM PF08534.


ensembl_gene_id: HMPREF0299_7265
symbol: ldh
gene_biotype: protein_coding
description:
  L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.


ensembl_gene_id: HMPREF0299_7284
symbol: EFM49367.1
gene_biotype: protein_coding
description:
  Peptidase, M23 family; Identified by match to protein family HMM PF01464; match to protein family HMM PF01551.


ensembl_gene_id: HMPREF0299_7293
symbol: agcS
gene_biotype: protein_coding
description:
  Amino acid carrier protein; Identified by match to protein family HMM PF01235; match to protein family HMM TIGR00835.


ensembl_gene_id: HMPREF0299_7300
symbol: pheA
gene_biotype: protein_coding
description:
  Prephenate dehydratase; Identified by match to protein family HMM PF00800; match to protein family HMM PF01842.


ensembl_gene_id: HMPREF0299_7312
symbol: EFM49267.1
gene_biotype: protein_coding
description:
  UbiC transcription regulator-associated domain protein; Identified by match to protein family HMM PF00392; match to protein family HMM PF07702.


ensembl_gene_id: HMPREF0299_7313
symbol: serS
gene_biotype: protein_coding
description:
  serine--tRNA ligase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).


ensembl_gene_id: HMPREF0299_7314
symbol: EFM49381.1
gene_biotype: protein_coding
description:
  Acyltransferase; Identified by match to protein family HMM PF01553; match to protein family HMM TIGR00530.


ensembl_gene_id: HMPREF0299_7318
symbol: glf
gene_biotype: protein_coding
description:
  UDP-galactopyranose mutase; Identified by match to protein family HMM PF03275; match to protein family HMM TIGR00031.


ensembl_gene_id: HMPREF0299_7320
symbol: EFM49405.1
gene_biotype: protein_coding
description:
  DnaK family protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF00012; Belongs to the heat shock protein 70 family.


ensembl_gene_id: HMPREF0299_7325
symbol: EFM49701.1
gene_biotype: protein_coding
description:
  Prenyltransferase, UbiA family; Identified by match to protein family HMM PF01040; Belongs to the UbiA prenyltransferase family.


ensembl_gene_id: HMPREF0299_7328
symbol: EFM49299.1
gene_biotype: protein_coding
description:
  Tat pathway signal sequence domain protein; Identified by match to protein family HMM PF00756; match to protein family HMM PF08310.


ensembl_gene_id: HMPREF0299_7335
symbol: EFM49430.1
gene_biotype: protein_coding
description:
  Beta-ketoacyl synthase, N-terminal domain protein; Identified by match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF00975; match to protein family HMM PF02801.


ensembl_gene_id: HMPREF0299_7347
symbol: trmB
gene_biotype: protein_coding
description:
  tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.


ensembl_gene_id: HMPREF0299_7348
symbol: pckG
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.


ensembl_gene_id: HMPREF0299_7363
symbol: EFM49555.1
gene_biotype: protein_coding
description:
  Glycosyl hydrolase family 3 N-terminal domain protein; Identified by match to protein family HMM PF00933.


ensembl_gene_id: HMPREF0299_7367
symbol: EFM49525.1
gene_biotype: protein_coding
description:
  ABC transporter, substrate-binding protein, QAT family; Identified by match to protein family HMM PF04069.


ensembl_gene_id: HMPREF0299_7373
symbol: dcd
gene_biotype: protein_coding
description:
  dCTP deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.


ensembl_gene_id: HMPREF0299_7384
symbol: EFM49313.1
gene_biotype: protein_coding
description:
  Cysteine-rich domain protein; Identified by match to protein family HMM PF00037; match to protein family HMM PF02754.


ensembl_gene_id: HMPREF0299_7394
symbol: EFM49278.1
gene_biotype: protein_coding
description:
  Putative 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Identified by match to protein family HMM PF01048.


ensembl_gene_id: HMPREF0299_7396
symbol: EFM49639.1
gene_biotype: protein_coding
description:
  Nitrite/sulfite reductase ferredoxin domain protein; Identified by match to protein family HMM PF01077; match to protein family HMM PF03460; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.


ensembl_gene_id: HMPREF0299_7398
symbol: EFM49616.1
gene_biotype: protein_coding
description:
  Adenylylsulfate reductase, thioredoxin dependent; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.


ensembl_gene_id: HMPREF0299_7400
symbol: cysN
gene_biotype: protein_coding
description:
  Sulfate adenylyltransferase, large subunit; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.


ensembl_gene_id: HMPREF0299_7408
symbol: grpE
gene_biotype: protein_coding
description:
  Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...]


ensembl_gene_id: HMPREF0299_7436
symbol: EFM49466.1
gene_biotype: protein_coding
description:
  ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005; match to protein family HMM PF00664; match to protein family HMM PF03412.


ensembl_gene_id: HMPREF0299_7441
symbol: dnaJ
gene_biotype: protein_coding
description:
  Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]


ensembl_gene_id: HMPREF0299_7450
symbol: clpB
gene_biotype: protein_coding
description:
  ATP-dependent chaperone protein ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.


ensembl_gene_id: HMPREF0299_7453
symbol: pyrE
gene_biotype: protein_coding
description:
  Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).


ensembl_gene_id: HMPREF0299_7468
symbol: ptbA
gene_biotype: protein_coding
description:
  PTS system, glucose subfamily, IIA component; Identified by match to protein family HMM PF00358; match to protein family HMM TIGR00830.


ensembl_gene_id: HMPREF0299_7469
symbol: EFM49633.1
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1; Identified by match to protein family HMM PF00358.


ensembl_gene_id: HMPREF0299_7480
symbol: fbaA
gene_biotype: protein_coding
description:
  Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.


ensembl_gene_id: HMPREF0299_7482
symbol: EFM49560.1
gene_biotype: protein_coding
description:
  Interferon-induced transmembrane protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF0299_7489
symbol: purA
gene_biotype: protein_coding
description:
  Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.


ensembl_gene_id: HMPREF0299_7491
symbol: purT
gene_biotype: protein_coding
description:
  Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family.


ensembl_gene_id: HMPREF0299_7493
symbol: pta
gene_biotype: protein_coding
description:
  Phosphate acetyltransferase; Identified by match to protein family HMM PF01515; match to protein family HMM TIGR00651.


ensembl_gene_id: HMPREF0299_7494
symbol: ackA
gene_biotype: protein_coding
description:
  Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.


ensembl_gene_id: HMPREF0299_7497
symbol: EFM49344.1
gene_biotype: protein_coding
description:
  ABC transporter, substrate-binding protein, family 3; Identified by match to protein family HMM PF00497; Belongs to the bacterial solute-binding protein 3 family.


ensembl_gene_id: HMPREF0299_7504
symbol: EFM49628.1
gene_biotype: protein_coding
description:
  Identified by match to protein family HMM PF00614; Belongs to the phospholipase D family. Cardiolipin synthase subfamily.


ensembl_gene_id: HMPREF0299_7510
symbol: EFM49274.1
gene_biotype: protein_coding
description:
  Carboxylate-amine ligase, YbdK family; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.


ensembl_gene_id: HMPREF0299_7524
symbol: ppa
gene_biotype: protein_coding
description:
  Inorganic diphosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.


ensembl_gene_id: HMPREF0299_7525
symbol: dacB
gene_biotype: protein_coding
description:
  D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase; Identified by match to protein family HMM PF02113; match to protein family HMM TIGR00666.


ensembl_gene_id: HMPREF0299_7526
symbol: tilS
gene_biotype: protein_coding
description:
  tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.


ensembl_gene_id: HMPREF0299_7528
symbol: hpt
gene_biotype: protein_coding
description:
  Hypoxanthine phosphoribosyltransferase; Identified by match to protein family HMM PF00156; match to protein family HMM TIGR01203; Belongs to the purine/pyrimidine phosphoribosyltransferase family.


ensembl_gene_id: HMPREF0299_7529
symbol: hflB
gene_biotype: protein_coding
description:
  ATP-dependent metallopeptidase HflB; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family.  In the central section; belongs to the AAA ATPase family.


ensembl_gene_id: HMPREF0299_7530
symbol: folE
gene_biotype: protein_coding
description:
  GTP cyclohydrolase I; Identified by match to protein family HMM PF01227; match to protein family HMM TIGR00063.


ensembl_gene_id: HMPREF0299_7531
symbol: folP
gene_biotype: protein_coding
description:
  Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.


ensembl_gene_id: HMPREF0299_7532
symbol: folB
gene_biotype: protein_coding
description:
  Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.


ensembl_gene_id: HMPREF0299_7533
symbol: folK
gene_biotype: protein_coding
description:
  2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Identified by match to protein family HMM PF01288; match to protein family HMM TIGR01498.


ensembl_gene_id: HMPREF0299_7537
symbol: EFM49651.1
gene_biotype: protein_coding
description:
  Putative pantoate--beta-alanine ligase; Identified by match to protein family HMM PF02569; Belongs to the pantothenate synthetase family.


ensembl_gene_id: HMPREF0299_7538
symbol: lysS
gene_biotype: protein_coding
description:
  lysine--tRNA ligase; Identified by match to protein family HMM PF00152; match to protein family HMM PF01336; match to protein family HMM TIGR00499; Belongs to the class-II aminoacyl-tRNA synthetase family.


ensembl_gene_id: HMPREF0299_7541
symbol: clpC
gene_biotype: protein_coding
description:
  ATPase family associated with various cellular activities (AAA); Identified by match to protein family HMM PF00004; match to protein family HMM PF02151; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM PF07728; Belongs to the ClpA/ClpB family.


ensembl_gene_id: HMPREF0299_7545
symbol: rmlD-3
gene_biotype: protein_coding
description:
  NAD dependent epimerase/dehydratase family protein; Identified by match to protein family HMM PF01370; match to protein family HMM PF04321.


ensembl_gene_id: HMPREF0299_7548
symbol: EFM49392.1
gene_biotype: protein_coding
description:
  Putative A/G-specific adenine glycosylase; Identified by match to protein family HMM PF00633; match to protein family HMM PF00730.


ensembl_gene_id: HMPREF0299_7549
symbol: cah
gene_biotype: protein_coding
description:
  Carbonate dehydratase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family.


ensembl_gene_id: HMPREF0299_7551
symbol: radA
gene_biotype: protein_coding
description:
  DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.


ensembl_gene_id: HMPREF0299_7560
symbol: ispD
gene_biotype: protein_coding
description:
  2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).


ensembl_gene_id: HMPREF0299_7561
symbol: ispF
gene_biotype: protein_coding
description:
  2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).


ensembl_gene_id: HMPREF0299_7562
symbol: cysS
gene_biotype: protein_coding
description:
  cysteine--tRNA ligase; Identified by match to protein family HMM PF01406; match to protein family HMM PF09190; match to protein family HMM PF09334; match to protein family HMM TIGR00435; Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: HMPREF0299_7563
symbol: EFM49588.1
gene_biotype: protein_coding
description:
  RNA methyltransferase, TrmH family, group 3; Identified by match to protein family HMM PF00588; match to protein family HMM PF08032; match to protein family HMM TIGR00186; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.


ensembl_gene_id: HMPREF0299_7568
symbol: otsA
gene_biotype: protein_coding
description:
  Putative alpha,alpha-trehalose-phosphate synthase (UDP-forming); Identified by match to protein family HMM PF00982.


ensembl_gene_id: HMPREF0299_7584
symbol: purD
gene_biotype: protein_coding
description:
  Phosphoribosylamine--glycine ligase; Identified by match to protein family HMM PF01071; match to protein family HMM PF02655; match to protein family HMM PF02843; match to protein family HMM PF02844; match to protein family HMM TIGR00877; Belongs to the GARS family.


ensembl_gene_id: HMPREF0299_7586
symbol: EFM49407.1
gene_biotype: protein_coding
description:
  Aminotransferase, class I/II; Identified by match to protein family HMM PF00155; match to protein family HMM PF00266.


ensembl_gene_id: HMPREF0299_7589
symbol: purB
gene_biotype: protein_coding
description:
  Adenylosuccinate lyase; Identified by match to protein family HMM PF00206; match to protein family HMM TIGR00928; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.


ensembl_gene_id: HMPREF0299_7591
symbol: purC
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazolesuccinocarboxamide synthase; Identified by match to protein family HMM PF01259; match to protein family HMM TIGR00081; Belongs to the SAICAR synthetase family.


ensembl_gene_id: HMPREF0299_7592
symbol: EFM49562.1
gene_biotype: protein_coding
description:
  Peptidase, S9A/B/C family, catalytic domain protein; Identified by match to protein family HMM PF00326; match to protein family HMM PF02897.


ensembl_gene_id: HMPREF0299_7594
symbol: purS
gene_biotype: protein_coding
description:
  Phosphoribosylformylglycinamidine synthase, purS protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...]


ensembl_gene_id: HMPREF0299_7595
symbol: purQ
gene_biotype: protein_coding
description:
  Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...]


ensembl_gene_id: HMPREF0299_7596
symbol: purL
gene_biotype: protein_coding
description:
  Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist  [...]


ensembl_gene_id: HMPREF0299_7600
symbol: purF
gene_biotype: protein_coding
description:
  Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.


ensembl_gene_id: HMPREF0299_7601
symbol: purM
gene_biotype: protein_coding
description:
  Phosphoribosylformylglycinamidine cyclo-ligase; Identified by match to protein family HMM PF00586; match to protein family HMM PF02769; match to protein family HMM TIGR00878.


ensembl_gene_id: HMPREF0299_7603
symbol: EFM49369.1
gene_biotype: protein_coding
description:
  Glycine cleavage T-protein; Identified by match to protein family HMM PF01571; match to protein family HMM TIGR03317; Belongs to the GcvT family.


ensembl_gene_id: HMPREF0299_7608
symbol: mshD
gene_biotype: protein_coding
description:
  Mycothiol biosynthesis acetyltransferase; Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.


ensembl_gene_id: HMPREF0299_7613
symbol: EFM49347.1
gene_biotype: protein_coding
description:
  TIM-barrel protein, nifR3 family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.


ensembl_gene_id: HMPREF0299_7614
symbol: EFM49427.1
gene_biotype: protein_coding
description:
  Succinate CoA transferase; Identified by match to protein family HMM PF02550; match to protein family HMM TIGR03458.


ensembl_gene_id: HMPREF0299_7619
symbol: proV
gene_biotype: protein_coding
description:
  Glycine betaine/L-proline transport ATP binding subunit; Identified by match to protein family HMM PF00005; match to protein family HMM PF00571.


ensembl_gene_id: HMPREF0299_7627
symbol: EFM49481.1
gene_biotype: protein_coding
description:
  WXG100 family type VII secretion target; Identified by match to protein family HMM TIGR03930; Belongs to the WXG100 family.


ensembl_gene_id: HMPREF0299_7644
symbol: EFM49255.1
gene_biotype: protein_coding
description:
  Response regulator receiver domain protein; Identified by match to protein family HMM PF00072; match to protein family HMM PF00196; match to protein family HMM PF04545.


ensembl_gene_id: HMPREF0299_7661
symbol: EFM49529.1
gene_biotype: protein_coding
description:
  Methyltransferase domain protein; Identified by match to protein family HMM PF05401; match to protein family HMM PF08241; match to protein family HMM PF08242.


ensembl_gene_id: HMPREF0299_7663
symbol: EFM49374.1
gene_biotype: protein_coding
description:
  Phenazine biosynthesis protein, PhzF family; Identified by match to protein family HMM PF02567; match to protein family HMM TIGR00654.


ensembl_gene_id: HMPREF0299_7675
symbol: cysE
gene_biotype: protein_coding
description:
  Serine O-acetyltransferase; Identified by match to protein family HMM PF00132; match to protein family HMM TIGR01172.


ensembl_gene_id: HMPREF0299_7676
symbol: cysK
gene_biotype: protein_coding
description:
  Cysteine synthase A; Identified by match to protein family HMM PF00291; match to protein family HMM TIGR01136; match to protein family HMM TIGR01139; Belongs to the cysteine synthase/cystathionine beta- synthase family.


ensembl_gene_id: HMPREF0299_7678
symbol: EFM49587.1
gene_biotype: protein_coding
description:
  Transcriptional regulator, LuxR family; Identified by match to protein family HMM PF00196; match to protein family HMM PF01590.


ensembl_gene_id: HMPREF0299_7679
symbol: EFM49652.1
gene_biotype: protein_coding
description:
  ATP:cob(I)alamin adenosyltransferase; Identified by match to protein family HMM PF01923; match to protein family HMM TIGR00636; Belongs to the Cob(I)alamin adenosyltransferase family.


ensembl_gene_id: HMPREF0299_7680
symbol: murA
gene_biotype: protein_coding
description:
  UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.


