# geneInfo

ensembl_gene_id: Hden_0002
symbol: dnaA
gene_biotype: protein_coding
description:
  Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.


ensembl_gene_id: Hden_0003
symbol: Hden_0003
gene_biotype: protein_coding
description:
  DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]


ensembl_gene_id: Hden_0004
symbol: Hden_0004
gene_biotype: protein_coding
description:
  Protein of unknown function DUF559; KEGG: rpb:RPB_1094 hypothetical protein; manually curated; PFAM: protein of unknown function DUF559.


ensembl_gene_id: Hden_0005
symbol: recF
gene_biotype: protein_coding
description:
  SMC domain protein; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.


ensembl_gene_id: Hden_0006
symbol: gyrB
gene_biotype: protein_coding
description:
  DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.


ensembl_gene_id: Hden_0008
symbol: Hden_0008
gene_biotype: protein_coding
description:
  PFAM: sodium/hydrogen exchanger; TrkA-N domain protein; KEGG: mno:Mnod_5461 sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.


ensembl_gene_id: Hden_0009
symbol: Hden_0009
gene_biotype: protein_coding
description:
  KEGG: pla:Plav_0008 1A family penicillin-binding protein; TIGRFAM: penicillin-binding protein, 1A family; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase.


ensembl_gene_id: Hden_0011
symbol: Hden_0011
gene_biotype: protein_coding
description:
  PFAM: electron transport protein SCO1/SenC; KEGG: pla:Plav_0014 classical-complement-pathway C3/C5 convertase.


ensembl_gene_id: Hden_0012
symbol: Hden_0012
gene_biotype: protein_coding
description:
  Integral membrane sensor signal transduction histidine kinase; KEGG: mlo:mlr5307 two-component, sensor histidine protein kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein.


ensembl_gene_id: Hden_0013
symbol: Hden_0013
gene_biotype: protein_coding
description:
  Response regulator receiver protein; KEGG: pla:Plav_0018 two component Fis family transcriptional regulator; PFAM: response regulator receiver; SMART: response regulator receiver.


ensembl_gene_id: Hden_0019
symbol: argD
gene_biotype: protein_coding
description:
  KEGG: azc:AZC_4028 acetylornithine and succinylornithine aminotransferase; TIGRFAM: acetylornithine and succinylornithine aminotransferase; PFAM: aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.


ensembl_gene_id: Hden_0020
symbol: Hden_0020
gene_biotype: protein_coding
description:
  Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.


ensembl_gene_id: Hden_0021
symbol: Hden_0021
gene_biotype: protein_coding
description:
  Hsp33 protein; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress; Belongs to the HSP33 family.


ensembl_gene_id: Hden_0023
symbol: Hden_0023
gene_biotype: protein_coding
description:
  KEGG: bmj:BMULJ_06091 acetylornithine deacetylase; TIGRFAM: acetylornithine deacetylase (ArgE); PFAM: peptidase M20; peptidase dimerisation domain protein.


ensembl_gene_id: Hden_0025
symbol: metZ
gene_biotype: protein_coding
description:
  O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.


ensembl_gene_id: Hden_0026
symbol: Hden_0026
gene_biotype: protein_coding
description:
  PFAM: 2-deoxycytidine 5-triphosphate deaminase; KEGG: bra:BRADO6769 2'-deoxycytidine 5'-triphosphate deaminase.


ensembl_gene_id: Hden_0029
symbol: Hden_0029
gene_biotype: protein_coding
description:
  KEGG: rpt:Rpal_3302 histone family protein DNA-binding protein; PFAM: histone family protein DNA-binding protein; SMART: histone family protein DNA-binding protein; Belongs to the bacterial histone-like protein family.


ensembl_gene_id: Hden_0030
symbol: dapE
gene_biotype: protein_coding
description:
  Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily.


ensembl_gene_id: Hden_0032
symbol: dapD
gene_biotype: protein_coding
description:
  KEGG: mch:Mchl_1853 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; TIGRFAM: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family.


ensembl_gene_id: Hden_0034
symbol: Hden_0034
gene_biotype: protein_coding
description:
  PFAM: Redoxin domain protein; KEGG: pla:Plav_1603 alkyl hydroperoxide reductase/thiol specific antioxidant/Mal allergen.


ensembl_gene_id: Hden_0035
symbol: argH
gene_biotype: protein_coding
description:
  KEGG: mno:Mnod_7298 argininosuccinate lyase; TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase.


ensembl_gene_id: Hden_0037
symbol: lysA
gene_biotype: protein_coding
description:
  Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.


ensembl_gene_id: Hden_0040
symbol: Hden_0040
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: pla:Plav_1268 LysR family transcriptional regulator.


ensembl_gene_id: Hden_0043
symbol: Hden_0043
gene_biotype: protein_coding
description:
  KEGG: mno:Mnod_1733 penicillin-binding protein 1C; TIGRFAM: penicillin-binding protein 1C; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; Penicillin-binding domain protein.


ensembl_gene_id: Hden_0044
symbol: Hden_0044
gene_biotype: protein_coding
description:
  PFAM: alpha-2-macroglobulin domain protein; alpha-2-macroglobulin domain protein 2; KEGG: bja:blr4438 hypothetical protein.


ensembl_gene_id: Hden_0045
symbol: Hden_0045
gene_biotype: protein_coding
description:
  Hypothetical protein; KEGG: gem:GM21_1811 response regulator receiver modulated metal dependent phosphohydrolase.


ensembl_gene_id: Hden_0052
symbol: Hden_0052
gene_biotype: protein_coding
description:
  Hypothetical protein; KEGG: scb:SCAB_38741 putative pyridoxal-5'-phosphate dependent aminotransferase.


ensembl_gene_id: Hden_0054
symbol: Hden_0054
gene_biotype: protein_coding
description:
  KEGG: rpb:RPB_1345 serine-type D-Ala-D-Ala carboxypeptidase; PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; Belongs to the peptidase S11 family.


ensembl_gene_id: Hden_0055
symbol: Hden_0055
gene_biotype: protein_coding
description:
  KEGG: cwo:Cwoe_3291 drug resistance transporter, EmrB/QacA subfamily; TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1.


ensembl_gene_id: Hden_0058
symbol: Hden_0058
gene_biotype: protein_coding
description:
  Band 7 protein; KEGG: mth:MTH1780 stomatin-like protein; PFAM: band 7 protein; SMART: band 7 protein.


ensembl_gene_id: Hden_0059
symbol: Hden_0059
gene_biotype: protein_coding
description:
  PFAM: multiple antibiotic resistance (MarC)-related protein; KEGG: ccs:CCNA_01734 MarC family integral membrane protein.


ensembl_gene_id: Hden_0068
symbol: Hden_0068
gene_biotype: protein_coding
description:
  KEGG: mno:Mnod_4909 protein of unknown function DUF1332; PFAM: protein of unknown function DUF1332; heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein.


ensembl_gene_id: Hden_0069
symbol: Hden_0069
gene_biotype: protein_coding
description:
  N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD; KEGG: azc:AZC_4549 N-acetylmuramoyl-L-alanine amidase; PFAM: N-acetylmuramoyl-L-alanine amidase family 2; Peptidoglycan-binding domain 1 protein; SMART: N-acetylmuramoyl-L-alanine amidase family 2.


ensembl_gene_id: Hden_0072
symbol: Hden_0072
gene_biotype: protein_coding
description:
  Hypothetical protein; KEGG: mpo:Mpop_3271 conserved hypothetical protein; putative exported protein.


ensembl_gene_id: Hden_0076
symbol: Hden_0076
gene_biotype: protein_coding
description:
  4Fe-4S ferredoxin iron-sulfur binding domain protein; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.


ensembl_gene_id: Hden_0079
symbol: Hden_0079
gene_biotype: protein_coding
description:
  GntR domain protein; KEGG: azc:AZC_1369 transcriptional regulatory protein; PFAM: GntR domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; GntR domain protein.


ensembl_gene_id: Hden_0081
symbol: Hden_0081
gene_biotype: protein_coding
description:
  PFAM: amino acid permease-associated region; KEGG: azc:AZC_1370 amino acid transporter permease protein.


ensembl_gene_id: Hden_0083
symbol: Hden_0083
gene_biotype: protein_coding
description:
  PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: ara:Arad_8374 ferredoxin protein.


ensembl_gene_id: Hden_0085
symbol: Hden_0085
gene_biotype: protein_coding
description:
  PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel; KEGG: xau:Xaut_3187 glycine cleavage T protein (aminomethyl transferase); Belongs to the GcvT family.


ensembl_gene_id: Hden_0087
symbol: Hden_0087
gene_biotype: protein_coding
description:
  PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: bmr:BMI_II478 glyoxalase, putative.


ensembl_gene_id: Hden_0089
symbol: Hden_0089
gene_biotype: protein_coding
description:
  PFAM: 4'-phosphopantetheinyl transferase; KEGG: vei:Veis_2444 4'-phosphopantetheinyl transferase; Belongs to the P-Pant transferase superfamily.


ensembl_gene_id: Hden_0090
symbol: Hden_0090
gene_biotype: protein_coding
description:
  Amino acid adenylation domain protein; KEGG: dma:DMR_01570 putative non-ribosomal peptide synthetase; TIGRFAM: amino acid adenylation domain protein; non-ribosomal peptide synthetase; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; transferase hexapeptide repeat containing protein; Belongs to the ATP-dependent AMP-binding enzyme family.


ensembl_gene_id: Hden_0092
symbol: Hden_0092
gene_biotype: protein_coding
description:
  KEGG: mes:Meso_0777 UDP-galactose 4-epimerase; TIGRFAM: UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family.


ensembl_gene_id: Hden_0096
symbol: Hden_0096
gene_biotype: protein_coding
description:
  PFAM: Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein; KEGG: msl:Msil_1827 alcohol dehydrogenase GroES domain protein.


ensembl_gene_id: Hden_0097
symbol: Hden_0097
gene_biotype: protein_coding
description:
  KEGG: tgr:Tgr7_1944 flavin reductase domain protein FMN-binding; PFAM: flavin reductase domain protein FMN-binding; SMART: flavin reductase domain protein FMN-binding.


ensembl_gene_id: Hden_0100
symbol: fcl
gene_biotype: protein_coding
description:
  NAD-dependent epimerase/dehydratase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.


ensembl_gene_id: Hden_0101
symbol: gmd
gene_biotype: protein_coding
description:
  GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose.


ensembl_gene_id: Hden_0102
symbol: Hden_0102
gene_biotype: protein_coding
description:
  KEGG: tgr:Tgr7_2287 methyl-accepting chemotaxis sensory transducer; PFAM: chemotaxis sensory transducer; extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; chemotaxis sensory transducer.


ensembl_gene_id: Hden_0103
symbol: folD
gene_biotype: protein_coding
description:
  Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.


ensembl_gene_id: Hden_0104
symbol: fhs
gene_biotype: protein_coding
description:
  KEGG: rhi:NGR_c23560 formate-tetrahydrofolate ligase; PFAM: formate-tetrahydrofolate ligase FTHFS; Belongs to the formate--tetrahydrofolate ligase family.


ensembl_gene_id: Hden_0105
symbol: Hden_0105
gene_biotype: protein_coding
description:
  PFAM: polysaccharide biosynthesis protein CapD; KEGG: rma:Rmag_0886 polysaccharide biosynthesis protein CapD.


ensembl_gene_id: Hden_0109
symbol: Hden_0109
gene_biotype: protein_coding
description:
  KEGG: bgl:bglu_1g21240 P42.1; manually curated; PFAM: Pathogenesis-related transcriptional factor and ERF protein; HNH endonuclease.


ensembl_gene_id: Hden_0110
symbol: Hden_0110
gene_biotype: protein_coding
description:
  Hypothetical protein; KEGG: aco:Amico_0795 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein.


ensembl_gene_id: Hden_0124
symbol: Hden_0124
gene_biotype: protein_coding
description:
  Phage-type endonuclease; KEGG: lhk:LHK_01497 exonuclease; TIGRFAM: phage-type endonuclease; PFAM: YqaJ viral recombinase family.


ensembl_gene_id: Hden_0132
symbol: Hden_0132
gene_biotype: protein_coding
description:
  Helix-turn-helix domain protein; KEGG: ere:EUBREC_0387 hypothetical protein; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein.


ensembl_gene_id: Hden_0147
symbol: Hden_0147
gene_biotype: protein_coding
description:
  KEGG: nha:Nham_2362 hypothetical protein; PFAM: Pathogenesis-related transcriptional factor and ERF protein; HNH endonuclease; SMART: HNH nuclease.


ensembl_gene_id: Hden_0150
symbol: Hden_0150
gene_biotype: protein_coding
description:
  KEGG: api:100159509 similar to excision repair cross-complementing rodent repair deficiency, complementation group 4.


ensembl_gene_id: Hden_0155
symbol: Hden_0155
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF264; KEGG: mlo:mll0463 bacteriophage terminase large subunit-like protein.


ensembl_gene_id: Hden_0182
symbol: Hden_0182
gene_biotype: protein_coding
description:
  PFAM: polysaccharide biosynthesis protein; KEGG: dda:Dd703_0209 polysaccharide biosynthesis protein.


ensembl_gene_id: Hden_0185
symbol: Hden_0185
gene_biotype: protein_coding
description:
  PFAM: polysaccharide biosynthesis protein CapD; Polysaccharide biosynthesis domain protein; KEGG: pap:PSPA7_1980 polysaccharide biosynthesis protein; O-antigen biosynthesis protein.


ensembl_gene_id: Hden_0186
symbol: Hden_0186
gene_biotype: protein_coding
description:
  PFAM: NAD-dependent epimerase/dehydratase; KEGG: pen:PSEEN1501 nucleoside-diphosphate-sugar epimerase WbjC.


ensembl_gene_id: Hden_0187
symbol: Hden_0187
gene_biotype: protein_coding
description:
  TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; KEGG: tmz:Tmz1t_3803 UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family.


ensembl_gene_id: Hden_0190
symbol: Hden_0190
gene_biotype: protein_coding
description:
  TIGRFAM: sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family; KEGG: avn:Avin_30060 trimeric LpxA-like family protein.


ensembl_gene_id: Hden_0191
symbol: Hden_0191
gene_biotype: protein_coding
description:
  Glutamine--scyllo-inositol transaminase; KEGG: pph:Ppha_0579 DegT/DnrJ/EryC1/StrS aminotransferase; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; Belongs to the DegT/DnrJ/EryC1 family.


ensembl_gene_id: Hden_0194
symbol: Hden_0194
gene_biotype: protein_coding
description:
  PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: bph:Bphy_5960 NADH:flavin oxidoreductase/NADH oxidase.


ensembl_gene_id: Hden_0196
symbol: Hden_0196
gene_biotype: protein_coding
description:
  PFAM: Electron transfer flavoprotein alpha/beta-subunit; protein of unknown function DUF224 cysteine-rich region domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: bph:Bphy_5959 hypothetical protein.


ensembl_gene_id: Hden_0197
symbol: Hden_0197
gene_biotype: protein_coding
description:
  KEGG: bph:Bphy_5956 electron transfer flavoprotein alpha subunit; PFAM: Electron transfer flavoprotein alpha/beta-subunit; Electron transfer flavoprotein alpha subunit; SMART: Electron transfer flavoprotein alpha/beta-subunit.


ensembl_gene_id: Hden_0199
symbol: mntP
gene_biotype: protein_coding
description:
  Protein of unknown function DUF204; Probably functions as a manganese efflux pump. Belongs to the MntP (TC 9.B.29) family.


ensembl_gene_id: Hden_0201
symbol: rplU
gene_biotype: protein_coding
description:
  Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.


ensembl_gene_id: Hden_0202
symbol: rpmA
gene_biotype: protein_coding
description:
  KEGG: avi:Avi_4287 50S ribosomal protein L27; TIGRFAM: ribosomal protein L27; PFAM: ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family.


ensembl_gene_id: Hden_0204
symbol: obg
gene_biotype: protein_coding
description:
  GTP-binding protein Obg/CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.


ensembl_gene_id: Hden_0205
symbol: Hden_0205
gene_biotype: protein_coding
description:
  PFAM: sodium/calcium exchanger membrane region; KEGG: rpe:RPE_4095 sodium/calcium exchanger membrane region.


ensembl_gene_id: Hden_0206
symbol: proB
gene_biotype: protein_coding
description:
  Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.


ensembl_gene_id: Hden_0207
symbol: proA
gene_biotype: protein_coding
description:
  Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.


ensembl_gene_id: Hden_0208
symbol: nadD
gene_biotype: protein_coding
description:
  Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).


ensembl_gene_id: Hden_0209
symbol: rsfS
gene_biotype: protein_coding
description:
  Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.


ensembl_gene_id: Hden_0210
symbol: rlmH
gene_biotype: protein_coding
description:
  Protein of unknown function DUF163; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family.


ensembl_gene_id: Hden_0212
symbol: Hden_0212
gene_biotype: protein_coding
description:
  PFAM: short-chain dehydrogenase/reductase SDR; KEGG: alv:Alvin_0717 short-chain dehydrogenase/reductase SDR; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: Hden_0213
symbol: Hden_0213
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF306 Meta and HslJ; KEGG: msl:Msil_0590 protein of unknown function DUF306 MetA and HslJ.


ensembl_gene_id: Hden_0214
symbol: Hden_0214
gene_biotype: protein_coding
description:
  PFAM: acyl-CoA dehydrogenase domain protein; KEGG: pla:Plav_1613 acyl-CoA dehydrogenase domain-containing protein.


ensembl_gene_id: Hden_0216
symbol: Hden_0216
gene_biotype: protein_coding
description:
  KEGG: rsq:Rsph17025_3009 crotonyl-CoA reductase; TIGRFAM: crotonyl-CoA reductase; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein.


ensembl_gene_id: Hden_0218
symbol: Hden_0218
gene_biotype: protein_coding
description:
  TIGRFAM: methylmalonyl-CoA mutase, large subunit; KEGG: xau:Xaut_1197 methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase; cobalamin B12-binding domain protein.


ensembl_gene_id: Hden_0221
symbol: Hden_0221
gene_biotype: protein_coding
description:
  PFAM: glycoside hydrolase family 3 domain protein; KEGG: mag:amb1842 beta-glucosidase-related glycosidase.


ensembl_gene_id: Hden_0222
symbol: Hden_0222
gene_biotype: protein_coding
description:
  Transcriptional regulator of molybdate metabolism, LysR family; PFAM: regulatory protein LysR; KEGG: bja:bll3775 formate dehydrogenase.


ensembl_gene_id: Hden_0227
symbol: Hden_0227
gene_biotype: protein_coding
description:
  PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: bid:Bind_2970 TonB-dependent receptor.


ensembl_gene_id: Hden_0228
symbol: crcB
gene_biotype: protein_coding
description:
  CrcB protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.


ensembl_gene_id: Hden_0229
symbol: Hden_0229
gene_biotype: protein_coding
description:
  Methyltransferase; KEGG: msl:Msil_3037 methyltransferase; TIGRFAM: methyltransferase; PFAM: Protein of unknown function DUF2260.


ensembl_gene_id: Hden_0233
symbol: Hden_0233
gene_biotype: protein_coding
description:
  PFAM: Protein of unknown function DUF2189, transmembrane; KEGG: rhi:NGR_c15150 hypothetical protein.


ensembl_gene_id: Hden_0235
symbol: rsmH
gene_biotype: protein_coding
description:
  S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.


ensembl_gene_id: Hden_0237
symbol: Hden_0237
gene_biotype: protein_coding
description:
  KEGG: nha:Nham_1273 peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain.


ensembl_gene_id: Hden_0238
symbol: murE
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.


ensembl_gene_id: Hden_0239
symbol: murF
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate/D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.


ensembl_gene_id: Hden_0240
symbol: mraY
gene_biotype: protein_coding
description:
  phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.


ensembl_gene_id: Hden_0241
symbol: murD
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoylalanine/D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.


ensembl_gene_id: Hden_0242
symbol: Hden_0242
gene_biotype: protein_coding
description:
  PFAM: cell cycle protein; KEGG: xau:Xaut_1190 cell division protein FtsW; Belongs to the SEDS family.


ensembl_gene_id: Hden_0243
symbol: murG
gene_biotype: protein_coding
description:
  Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.


ensembl_gene_id: Hden_0248
symbol: ftsA
gene_biotype: protein_coding
description:
  Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.


ensembl_gene_id: Hden_0249
symbol: ftsZ
gene_biotype: protein_coding
description:
  Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.


ensembl_gene_id: Hden_0250
symbol: lpxC
gene_biotype: protein_coding
description:
  UDP-3-0-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family.


ensembl_gene_id: Hden_0251
symbol: bamD
gene_biotype: protein_coding
description:
  Outer membrane assembly lipoprotein YfiO; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: Hden_0252
symbol: ligA
gene_biotype: protein_coding
description:
  DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily.


ensembl_gene_id: Hden_0256
symbol: Hden_0256
gene_biotype: protein_coding
description:
  KEGG: ava:Ava_2736 heat shock protein DnaJ-like; PFAM: heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein.


ensembl_gene_id: Hden_0262
symbol: fumC
gene_biotype: protein_coding
description:
  Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.


ensembl_gene_id: Hden_0264
symbol: Hden_0264
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF1254; protein of unknown function DUF1214; KEGG: rec:RHECIAT_CH0002049 hypothetical protein.


ensembl_gene_id: Hden_0268
symbol: thyA
gene_biotype: protein_coding
description:
  Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.


ensembl_gene_id: Hden_0270
symbol: Hden_0270
gene_biotype: protein_coding
description:
  Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.


ensembl_gene_id: Hden_0274
symbol: Hden_0274
gene_biotype: protein_coding
description:
  SMART: PDZ/DHR/GLGF domain protein; TIGRFAM: protease Do; KEGG: azc:AZC_2572 serine protease DO-like protein; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; Belongs to the peptidase S1C family.


ensembl_gene_id: Hden_0275
symbol: psd
gene_biotype: protein_coding
description:
  Phosphatidylserine decarboxylase related protein; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).


ensembl_gene_id: Hden_0276
symbol: Hden_0276
gene_biotype: protein_coding
description:
  KEGG: rpe:RPE_2009 CDP-diacylglycerol--serine O-phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol/serine O-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: Hden_0277
symbol: Hden_0277
gene_biotype: protein_coding
description:
  TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; KEGG: tbd:Tbd_1239 mannose-1-phosphate guanylyltransferase (GDP); PFAM: Nucleotidyl transferase; mannose-6-phosphate isomerase type II.


ensembl_gene_id: Hden_0279
symbol: Hden_0279
gene_biotype: protein_coding
description:
  KEGG: pla:Plav_1358 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein.


ensembl_gene_id: Hden_0281
symbol: Hden_0281
gene_biotype: protein_coding
description:
  PFAM: Biopolymer transport protein ExbD/TolR; KEGG: rru:Rru_A2154 biopolymer transport protein ExbD/TolR.


ensembl_gene_id: Hden_0284
symbol: Hden_0284
gene_biotype: protein_coding
description:
  PFAM: lipopolysaccharide biosynthesis protein; KEGG: pla:Plav_1906 non-specific protein-tyrosine kinase.


ensembl_gene_id: Hden_0286
symbol: Hden_0286
gene_biotype: protein_coding
description:
  Glycerate dehydrogenase; KEGG: pla:Plav_2807 glyoxylate reductase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region.


ensembl_gene_id: Hden_0288
symbol: Hden_0288
gene_biotype: protein_coding
description:
  KEGG: rpa:RPA3811 excinuclease ABC subunit C; PFAM: Excinuclease ABC C subunit domain protein; SMART: Excinuclease ABC C subunit domain protein.


ensembl_gene_id: Hden_0294
symbol: Hden_0294
gene_biotype: protein_coding
description:
  PFAM: periplasmic solute binding protein; KEGG: rec:RHECIAT_CH0002848 zinc uptake ABC transporter, substrate-binding protein.


ensembl_gene_id: Hden_0295
symbol: Hden_0295
gene_biotype: protein_coding
description:
  Two component transcriptional regulator PhoB, winged helix family; TIGRFAM: phosphate regulon transcriptional regulatory protein PhoB; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: xau:Xaut_0202 two component transcriptional regulator; SMART: response regulator receiver; transcriptional regulator domain protein.


ensembl_gene_id: Hden_0297
symbol: pstB
gene_biotype: protein_coding
description:
  Phosphate ABC transporter, ATPase subunit; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.


ensembl_gene_id: Hden_0298
symbol: Hden_0298
gene_biotype: protein_coding
description:
  KEGG: mlo:mll3720 phosphate transport system permease protein PstA; TIGRFAM: phosphate ABC transporter, inner membrane subunit PstA; PFAM: binding-protein-dependent transport systems inner membrane component.


ensembl_gene_id: Hden_0299
symbol: Hden_0299
gene_biotype: protein_coding
description:
  Phosphate ABC transporter, inner membrane subunit PstC; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: Hden_0300
symbol: Hden_0300
gene_biotype: protein_coding
description:
  Phosphate ABC transporter, periplasmic phosphate-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import; Belongs to the PstS family.


ensembl_gene_id: Hden_0301
symbol: Hden_0301
gene_biotype: protein_coding
description:
  Multi-sensor signal transduction histidine kinase; KEGG: met:M446_1659 histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein.


ensembl_gene_id: Hden_0302
symbol: Hden_0302
gene_biotype: protein_coding
description:
  KEGG: bcm:Bcenmc03_1872 BadM/Rrf2 family transcriptional regulator; TIGRFAM: transcriptional regulator, Rrf2 family; PFAM: protein of unknown function UPF0074.


ensembl_gene_id: Hden_0304
symbol: Hden_0304
gene_biotype: protein_coding
description:
  PFAM: multicopper oxidase type 3; multicopper oxidase type 2; KEGG: azl:AZL_c02540 multicopper oxidase type 3.


ensembl_gene_id: Hden_0308
symbol: rimO
gene_biotype: protein_coding
description:
  MiaB-like tRNA modifying enzyme YliG; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily.


ensembl_gene_id: Hden_0309
symbol: Hden_0309
gene_biotype: protein_coding
description:
  KEGG: mno:Mnod_2658 cation diffusion facilitator family transporter; TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.


ensembl_gene_id: Hden_0310
symbol: Hden_0310
gene_biotype: protein_coding
description:
  PFAM: membrane-bound metal-dependent hydrolase; KEGG: alv:Alvin_0692 membrane-bound metal-dependent hydrolase.


ensembl_gene_id: Hden_0318
symbol: Hden_0318
gene_biotype: protein_coding
description:
  TIGRFAM: Flp pilus assembly protein CpaB; PFAM: SAF domain protein; KEGG: rpd:RPD_3519 Flp pilus assembly CpaB; SMART: SAF domain protein.


ensembl_gene_id: Hden_0319
symbol: Hden_0319
gene_biotype: protein_coding
description:
  PFAM: type II and III secretion system protein; transport-associated; KEGG: pla:Plav_0233 type II and III secretion system protein; Belongs to the bacterial secretin family.


ensembl_gene_id: Hden_0320
symbol: Hden_0320
gene_biotype: protein_coding
description:
  KEGG: pla:Plav_0234 pilus biogenesis lipoprotein CpaD; TIGRFAM: pilus (Caulobacter type) biogenesis lipoprotein CpaD; PFAM: Pilus biogenesis CpaD-related.


ensembl_gene_id: Hden_0326
symbol: Hden_0326
gene_biotype: protein_coding
description:
  PFAM: peptidase M17 leucyl aminopeptidase domain protein; KEGG: mex:Mext_2976 leucyl aminopeptidase; Belongs to the peptidase M17 family.


ensembl_gene_id: Hden_0331
symbol: Hden_0331
gene_biotype: protein_coding
description:
  Transcriptional regulator, AraC family; TIGRFAM: methylated-DNA/protein-cysteine methyltransferase; PFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding; Ada metal-binding domain protein; helix-turn-helix- domain containing protein AraC type; KEGG: sus:Acid_4009 DNA-O6-methylguanine--protein-cysteine S-methyltransferase / transcriptional regulator Ada; SMART: Helix-turn-helix, AraC domain.


ensembl_gene_id: Hden_0335
symbol: Hden_0335
gene_biotype: protein_coding
description:
  KEGG: YVTN beta-propeller repeat family protein; TIGRFAM: 40-residue YVTN family beta-propeller repeat protein; SMART: WD-40 repeat protein.


ensembl_gene_id: Hden_0337
symbol: Hden_0337
gene_biotype: protein_coding
description:
  PFAM: extracellular solute-binding protein family 3; KEGG: azl:AZL_a05230 extracellular solute-binding protein.


ensembl_gene_id: Hden_0340
symbol: Hden_0340
gene_biotype: protein_coding
description:
  TIGRFAM: PQQ-dependent dehydrogenase, methanol/ethanol family; PFAM: PQQ-dependent enzyme-like; Pyrrolo-quinoline quinone; KEGG: mch:Mchl_1540 PQQ-dependent dehydrogenase, methanol/ethanol family; SMART: Pyrrolo-quinoline quinone beta-propeller repeat.


ensembl_gene_id: Hden_0344
symbol: Hden_0344
gene_biotype: protein_coding
description:
  PFAM: Uracil-DNA glycosylase superfamily; KEGG: mrd:Mrad2831_3539 uracil-DNA glycosylase superfamily protein.


ensembl_gene_id: Hden_0349
symbol: Hden_0349
gene_biotype: protein_coding
description:
  Two component transcriptional regulator, winged helix family; KEGG: rle:RL1157 putative two-component response regulator transcriptional regulatory protein; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; transcriptional regulator domain protein.


ensembl_gene_id: Hden_0350
symbol: Hden_0350
gene_biotype: protein_coding
description:
  KEGG: rlt:Rleg2_0703 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein.


ensembl_gene_id: Hden_0352
symbol: Hden_0352
gene_biotype: protein_coding
description:
  KEGG: ccs:CCNA_01546 DEAD-box RNA helicase-like protein; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; DbpA RNA-binding domain protein; SMART: DEAD-like helicase; helicase domain protein; Belongs to the DEAD box helicase family.


ensembl_gene_id: Hden_0360
symbol: polA
gene_biotype: protein_coding
description:
  DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.


ensembl_gene_id: Hden_0361
symbol: Hden_0361
gene_biotype: protein_coding
description:
  KEGG: oca:OCAR_4132 polyhydroxyalkanoate depolymerase, intracellular; TIGRFAM: polyhydroxyalkanoate depolymerase, intracellular; PFAM: PHB de-polymerase domain protein.


ensembl_gene_id: Hden_0363
symbol: infA
gene_biotype: protein_coding
description:
  Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.


ensembl_gene_id: Hden_0364
symbol: Hden_0364
gene_biotype: protein_coding
description:
  KEGG: rru:Rru_A1521 cold-shock DNA-binding protein family protein; PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein.


ensembl_gene_id: Hden_0371
symbol: lepA
gene_biotype: protein_coding
description:
  GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.


ensembl_gene_id: Hden_0373
symbol: Hden_0373
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF125 transmembrane; Rubrerythrin; KEGG: azl:AZL_013670 hypothetical protein.


ensembl_gene_id: Hden_0374
symbol: Hden_0374
gene_biotype: protein_coding
description:
  Lytic murein transglycosylase; KEGG: bbt:BBta_2243 hypothetical protein; TIGRFAM: lytic murein transglycosylase; PFAM: Peptidoglycan-binding domain 1 protein.


ensembl_gene_id: Hden_0375
symbol: Hden_0375
gene_biotype: protein_coding
description:
  PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: met:M446_4539 FAD-dependent pyridine nucleotide-disulphide oxidoreductase.


ensembl_gene_id: Hden_0376
symbol: pheT
gene_biotype: protein_coding
description:
  TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; KEGG: pla:Plav_0221 phenylalanyl-tRNA synthetase, beta subunit.


ensembl_gene_id: Hden_0377
symbol: pheS
gene_biotype: protein_coding
description:
  KEGG: oca:OCAR_4439 phenylalanyl-tRNA synthetase, alpha subunit; TIGRFAM: phenylalanyl-tRNA synthetase, alpha subunit; PFAM: phenylalanyl-tRNA synthetase class IIc; aminoacyl tRNA synthetase class II domain protein; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.


ensembl_gene_id: Hden_0378
symbol: rplT
gene_biotype: protein_coding
description:
  Ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.


ensembl_gene_id: Hden_0379
symbol: rpmI
gene_biotype: protein_coding
description:
  KEGG: dsh:Dshi_0230 50S ribosomal protein L35; TIGRFAM: ribosomal protein L35; PFAM: ribosomal protein L35; Belongs to the bacterial ribosomal protein bL35 family.


ensembl_gene_id: Hden_0384
symbol: Hden_0384
gene_biotype: protein_coding
description:
  Putative transcriptional regulator, Crp/Fnr family; KEGG: amr:AM1_2994 cyclic nucleotide-binding protein, putative; PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding.


ensembl_gene_id: Hden_0385
symbol: infC
gene_biotype: protein_coding
description:
  Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.


ensembl_gene_id: Hden_0386
symbol: Hden_0386
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF1022; KEGG: tmz:Tmz1t_3771 protein of unknown function DUF1022.


ensembl_gene_id: Hden_0391
symbol: Hden_0391
gene_biotype: protein_coding
description:
  PFAM: NAD-dependent epimerase/dehydratase; KEGG: alv:Alvin_1682 NAD-dependent epimerase/dehydratase.


ensembl_gene_id: Hden_0392
symbol: queG
gene_biotype: protein_coding
description:
  Domain of unknown function DUF1730; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family.


ensembl_gene_id: Hden_0393
symbol: Hden_0393
gene_biotype: protein_coding
description:
  PFAM: Glutathione S-transferase domain; KEGG: mrd:Mrad2831_3133 glutathione S-transferase domain-containing protein.


ensembl_gene_id: Hden_0394
symbol: uppP
gene_biotype: protein_coding
description:
  Undecaprenol kinase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.


ensembl_gene_id: Hden_0395
symbol: Hden_0395
gene_biotype: protein_coding
description:
  Putative PTS IIA-like nitrogen-regulatory protein PtsN; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; KEGG: xau:Xaut_2034 PTS IIA-like nitrogen-regulatory protein PtsN.


ensembl_gene_id: Hden_0396
symbol: hpf
gene_biotype: protein_coding
description:
  Sigma 54 modulation protein/ribosomal protein S30EA; Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.


ensembl_gene_id: Hden_0397
symbol: Hden_0397
gene_biotype: protein_coding
description:
  RNA polymerase, sigma 54 subunit, RpoN; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.


ensembl_gene_id: Hden_0398
symbol: Hden_0398
gene_biotype: protein_coding
description:
  KEGG: bbt:BBta_0122 putative ABC transporter ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase.


ensembl_gene_id: Hden_0399
symbol: Hden_0399
gene_biotype: protein_coding
description:
  PFAM: OstA family protein; protein of unknown function DUF1239; KEGG: pla:Plav_0194 cell envelope biogenesis YhbN.


ensembl_gene_id: Hden_0404
symbol: glsA
gene_biotype: protein_coding
description:
  Glutaminase; KEGG: atc:AGR_C_3412 thermolabile glutaminase (glutaminase A); PFAM: Glutaminase, core; Belongs to the glutaminase family.


ensembl_gene_id: Hden_0405
symbol: Hden_0405
gene_biotype: protein_coding
description:
  TIGRFAM: outer membrane autotransporter barrel domain protein; PFAM: Autotransporter beta- domain protein; KEGG: mei:Msip34_1977 outer membrane autotransporter barrel domain protein; SMART: Autotransporter beta- domain protein.


ensembl_gene_id: Hden_0407
symbol: mscL
gene_biotype: protein_coding
description:
  Large conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.


ensembl_gene_id: Hden_0409
symbol: Hden_0409
gene_biotype: protein_coding
description:
  PFAM: Na+/solute symporter; KEGG: tro:trd_1113 putative sodium/solute symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: Hden_0410
symbol: Hden_0410
gene_biotype: protein_coding
description:
  KEGG: pla:Plav_0503 proline iminopeptidase; TIGRFAM: proline iminopeptidase; PFAM: alpha/beta hydrolase fold; Belongs to the peptidase S33 family.


ensembl_gene_id: Hden_0412
symbol: Hden_0412
gene_biotype: protein_coding
description:
  KEGG: pla:Plav_0458 peptidoglycan binding domain-containing protein; PFAM: Sel1 domain protein repeat-containing protein; SMART: Sel1 domain protein repeat-containing protein.


ensembl_gene_id: Hden_0416
symbol: Hden_0416
gene_biotype: protein_coding
description:
  DEAD/H associated domain protein; KEGG: bmr:BMI_II819 ATP-dependent RNA helicase, DEAD/DEAH box family; PFAM: DEAD/H associated domain protein; DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein.


ensembl_gene_id: Hden_0417
symbol: pyrD
gene_biotype: protein_coding
description:
  Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.


ensembl_gene_id: Hden_0419
symbol: Hden_0419
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF262; protein of unknown function DUF1524 RloF; KEGG: mea:Mex_p20010 hypothetical protein.


ensembl_gene_id: Hden_0420
symbol: lysS
gene_biotype: protein_coding
description:
  TIGRFAM: lysyl-tRNA synthetase; KEGG: bmr:BMI_II784 lysyl-tRNA synthetase; PFAM: Lysyl-tRNA synthetase, class Ic; Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: Hden_0422
symbol: Hden_0422
gene_biotype: protein_coding
description:
  PFAM: peptidase U6 penicillin-insensitive murein endopeptidase; KEGG: rpe:RPE_0091 penicillin-insensitive murein endopeptidase.


ensembl_gene_id: Hden_0423
symbol: msrA
gene_biotype: protein_coding
description:
  Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.


ensembl_gene_id: Hden_0429
symbol: Hden_0429
gene_biotype: protein_coding
description:
  PFAM: Succinylglutamate desuccinylase/aspartoacylase; KEGG: msl:Msil_3423 succinylglutamate desuccinylase/aspartoacylase.


ensembl_gene_id: Hden_0434
symbol: Hden_0434
gene_biotype: protein_coding
description:
  Heavy metal efflux pump, CzcA family; KEGG: mea:Mex_1p2655 cobalt-zinc-cadmium resistance protein CzcA (cation efflux system protein CzcA); TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: Hden_0435
symbol: Hden_0435
gene_biotype: protein_coding
description:
  KEGG: mno:Mnod_2139 efflux transporter, RND family, MFP subunit; TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: biotin/lipoyl attachment domain-containing protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: Hden_0437
symbol: Hden_0437
gene_biotype: protein_coding
description:
  NusG antitermination factor; PFAM: NGN domain protein; KEGG: aeh:Mlg_0093 transcription antitermination protein NusG.


ensembl_gene_id: Hden_0438
symbol: Hden_0438
gene_biotype: protein_coding
description:
  PFAM: glycosyl transferase group 1; KEGG: mca:MCA1168 colanic acid biosynthesis glycosyl transferase, putative.


ensembl_gene_id: Hden_0441
symbol: Hden_0441
gene_biotype: protein_coding
description:
  PFAM: glycosyl transferase group 1; KEGG: rba:RB2471 putative poly(glycerol-phosphate) alpha-glucosyltransferase.


ensembl_gene_id: Hden_0451
symbol: Hden_0451
gene_biotype: protein_coding
description:
  PFAM: polysaccharide biosynthesis protein; KEGG: pjd:Pjdr2_1229 polysaccharide biosynthesis protein.


ensembl_gene_id: Hden_0453
symbol: Hden_0453
gene_biotype: protein_coding
description:
  KEGG: eba:ebA6795 hypothetical protein; PFAM: heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein.


ensembl_gene_id: Hden_0454
symbol: Hden_0454
gene_biotype: protein_coding
description:
  TIGRFAM: capsular exopolysaccharide family; KEGG: eba:ebA6797 exopolysaccharide biosynthesis protein; PFAM: lipopolysaccharide biosynthesis protein.


ensembl_gene_id: Hden_0456
symbol: Hden_0456
gene_biotype: protein_coding
description:
  Protein-tyrosine-phosphatase; KEGG: eba:ebA6802 capsular polysaccharide biosynthesis protein; PFAM: PHP domain protein.


ensembl_gene_id: Hden_0461
symbol: Hden_0461
gene_biotype: protein_coding
description:
  Transcriptional regulator, GntR family with aminotransferase domain protein; KEGG: rsk:RSKD131_3171 hypothetical protein; PFAM: regulatory protein GntR HTH; aminotransferase class I and II; SMART: regulatory protein GntR HTH.


ensembl_gene_id: Hden_0462
symbol: Hden_0462
gene_biotype: protein_coding
description:
  PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: scl:sce4293 alcohol dehydrogenase.


ensembl_gene_id: Hden_0463
symbol: Hden_0463
gene_biotype: protein_coding
description:
  KEGG: atc:AGR_C_4642 molybdate-binding periplasmic protein; TIGRFAM: molybdenum ABC transporter, periplasmic molybdate-binding protein; PFAM: extracellular solute-binding protein family 1.


ensembl_gene_id: Hden_0464
symbol: Hden_0464
gene_biotype: protein_coding
description:
  Molybdate ABC transporter, inner membrane subunit; Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: Hden_0465
symbol: Hden_0465
gene_biotype: protein_coding
description:
  KEGG: mno:Mnod_3727 molybdate ABC transporter, ATPase subunit; PFAM: ABC transporter related; SMART: AAA ATPase.


ensembl_gene_id: Hden_0466
symbol: Hden_0466
gene_biotype: protein_coding
description:
  Putative transcriptional regulator, ModE family; PFAM: regulatory protein LysR; KEGG: bbt:BBta_1642 LysR family transcriptional regulator.


ensembl_gene_id: Hden_0468
symbol: Hden_0468
gene_biotype: protein_coding
description:
  KEGG: nwi:Nwi_2361 ABC transporter, ATPase subunit; PFAM: ABC transporter related; SMART: AAA ATPase.


ensembl_gene_id: Hden_0471
symbol: Hden_0471
gene_biotype: protein_coding
description:
  PFAM: NHL repeat containing protein; KEGG: mno:Mnod_3274 glucose/sorbosone dehydrogenase-like protein.


ensembl_gene_id: Hden_0472
symbol: Hden_0472
gene_biotype: protein_coding
description:
  Hopanoid-associated sugar epimerase; KEGG: reu:Reut_B4897 NAD-dependent epimerase/dehydratase; TIGRFAM: hopanoid-associated sugar epimerase; PFAM: NAD-dependent epimerase/dehydratase.


ensembl_gene_id: Hden_0473
symbol: Hden_0473
gene_biotype: protein_coding
description:
  Hopene-associated glycosyltransferase HpnB; KEGG: bur:Bcep18194_B0107 glycosyl transferase family protein; TIGRFAM: hopene-associated glycosyltransferase HpnB; PFAM: glycosyl transferase family 2.


ensembl_gene_id: Hden_0474
symbol: Hden_0474
gene_biotype: protein_coding
description:
  KEGG: oca:OCAR_6674 squalene synthase HpnC; TIGRFAM: squalene synthase HpnC; PFAM: Squalene/phytoene synthase.


ensembl_gene_id: Hden_0475
symbol: Hden_0475
gene_biotype: protein_coding
description:
  TIGRFAM: squalene synthase HpnD; KEGG: mno:Mnod_7144 squalene synthase HpnD; PFAM: Squalene/phytoene synthase.


ensembl_gene_id: Hden_0476
symbol: Hden_0476
gene_biotype: protein_coding
description:
  KEGG: met:M446_6348 squalene-associated FAD-dependent desaturase; TIGRFAM: squalene-associated FAD-dependent desaturase; PFAM: amine oxidase.


ensembl_gene_id: Hden_0477
symbol: Hden_0477
gene_biotype: protein_coding
description:
  TIGRFAM: squalene/oxidosqualene cyclase; squalene-hopene cyclase; KEGG: mno:Mnod_7146 squalene-hopene cyclase; PFAM: Prenyltransferase/squalene oxidase.


ensembl_gene_id: Hden_0478
symbol: Hden_0478
gene_biotype: protein_coding
description:
  Hopanoid-associated phosphorylase; KEGG: bid:Bind_3157 hypothetical protein; TIGRFAM: hopanoid-associated phosphorylase; PFAM: purine or other phosphorylase family 1.


ensembl_gene_id: Hden_0479
symbol: Hden_0479
gene_biotype: protein_coding
description:
  TIGRFAM: hopanoid biosynthesis associated radical SAM protein HpnH; PFAM: Radical SAM domain protein; KEGG: msl:Msil_3245 hopanoid biosynthesis associated radical SAM protein HpnH; SMART: Elongator protein 3/MiaB/NifB.


ensembl_gene_id: Hden_0480
symbol: ispH
gene_biotype: protein_coding
description:
  Hydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.


ensembl_gene_id: Hden_0481
symbol: Hden_0481
gene_biotype: protein_coding
description:
  TIGRFAM: hopanoid biosynthesis associated RND transporter like protein HpnN; KEGG: msl:Msil_3246 hopanoid biosynthesis associated RND transporter like protein HpnN.


ensembl_gene_id: Hden_0482
symbol: Hden_0482
gene_biotype: protein_coding
description:
  TIGRFAM: hopanoid biosynthesis associated radical SAM protein HpnJ; PFAM: Radical SAM domain protein; KEGG: met:M446_6339 hopanoid biosynthesis associated radical SAM protein HpnJ; SMART: Elongator protein 3/MiaB/NifB.


ensembl_gene_id: Hden_0483
symbol: Hden_0483
gene_biotype: protein_coding
description:
  TIGRFAM: hopanoid biosynthesis associated glycosyl transferase protein HpnI; KEGG: hopanoid biosynthesis associated glycosyl transferase protein HpnI.


ensembl_gene_id: Hden_0485
symbol: Hden_0485
gene_biotype: protein_coding
description:
  KEGG: rru:Rru_A0056 toluene tolerance; TIGRFAM: hopanoid biosynthesis associated membrane protein HpnM; PFAM: toluene tolerance family protein.


ensembl_gene_id: Hden_0486
symbol: dxs
gene_biotype: protein_coding
description:
  Deoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.


ensembl_gene_id: Hden_0488
symbol: Hden_0488
gene_biotype: protein_coding
description:
  KEGG: reh:H16_B2171 cell wall biosynthesis glycosyltransferase; TIGRFAM: hopanoid biosynthesis associated glycosyl transferase protein HpnI; PFAM: glycosyl transferase family 2.


ensembl_gene_id: Hden_0489
symbol: Hden_0489
gene_biotype: protein_coding
description:
  KEGG: mag:amb3100 hypothetical protein; TIGRFAM: hopanoid biosynthesis associated protein HpnK; PFAM: YdjC family protein.


ensembl_gene_id: Hden_0492
symbol: Hden_0492
gene_biotype: protein_coding
description:
  Protein of unknown function DUF1289; KEGG: rru:Rru_A1617 hypothetical protein; manually curated; PFAM: protein of unknown function DUF1289.


ensembl_gene_id: Hden_0495
symbol: Hden_0495
gene_biotype: protein_coding
description:
  KEGG: rpc:RPC_2505 phosphoglycerate mutase; PFAM: Phosphoglycerate mutase; SMART: Phosphoglycerate mutase.


ensembl_gene_id: Hden_0496
symbol: Hden_0496
gene_biotype: protein_coding
description:
  PFAM: glycosyl transferase family 2; type IV pilus assembly PilZ; KEGG: bja:bll2448 cellulose synthase catalytic subunit.


ensembl_gene_id: Hden_0500
symbol: Hden_0500
gene_biotype: protein_coding
description:
  Manually curated; PFAM: ABC transporter related; ABC transporter transmembrane region; KEGG: nwi:Nwi_1064 ABC transporter, transmembrane region; SMART: AAA ATPase.


ensembl_gene_id: Hden_0501
symbol: Hden_0501
gene_biotype: protein_coding
description:
  Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.


ensembl_gene_id: Hden_0502
symbol: Hden_0502
gene_biotype: protein_coding
description:
  KEGG: mno:Mnod_4335 dTDP-glucose 4,6-dehydratase; TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.


ensembl_gene_id: Hden_0503
symbol: Hden_0503
gene_biotype: protein_coding
description:
  dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.


ensembl_gene_id: Hden_0510
symbol: Hden_0510
gene_biotype: protein_coding
description:
  PFAM: Oxidoreductase FAD-binding domain protein; oxidoreductase FAD/NAD(P)-binding domain protein; KEGG: mrd:Mrad2831_6157 oxidoreductase FAD/NAD(P)-binding subunit.


ensembl_gene_id: Hden_0513
symbol: Hden_0513
gene_biotype: protein_coding
description:
  PFAM: glutamate synthase alpha subunit domain protein; KEGG: ret:RHE_PE00420 formyl-methanofuran dehydrogenase domain-containing protein.


ensembl_gene_id: Hden_0514
symbol: Hden_0514
gene_biotype: protein_coding
description:
  PFAM: ferredoxin-dependent glutamate synthase; KEGG: rlg:Rleg_6577 ferredoxin-dependent glutamate synthase; Belongs to the glutamate synthase family.


ensembl_gene_id: Hden_0515
symbol: Hden_0515
gene_biotype: protein_coding
description:
  KEGG: mlo:mll7307 glutamine synthetase III; TIGRFAM: glutamine synthetase, type III; PFAM: glutamine synthetase catalytic region.


ensembl_gene_id: Hden_0517
symbol: Hden_0517
gene_biotype: protein_coding
description:
  PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: bja:bll6183 hypothetical protein.


ensembl_gene_id: Hden_0518
symbol: Hden_0518
gene_biotype: protein_coding
description:
  PFAM: glycoside hydrolase family 3 domain protein; KEGG: bid:Bind_0865 glycoside hydrolase family 3 protein.


ensembl_gene_id: Hden_0519
symbol: Hden_0519
gene_biotype: protein_coding
description:
  PFAM: Protein of unknown function DUF2470; pyridoxamine 5'-phosphate oxidase-related FMN-binding; KEGG: mes:Meso_2207 pyridoxamine 5'-phosphate oxidase-related, FMN-binding.


ensembl_gene_id: Hden_0520
symbol: Hden_0520
gene_biotype: protein_coding
description:
  HhH-GPD family protein; KEGG: rpc:RPC_4886 HhH-GPD; PFAM: HhH-GPD family protein; SMART: HhH-GPD family protein.


ensembl_gene_id: Hden_0521
symbol: msrB
gene_biotype: protein_coding
description:
  TIGRFAM: methionine-R-sulfoxide reductase; KEGG: ara:Arad_1327 methionine sulfoxide reductase B; PFAM: Methionine sulfoxide reductase B.


ensembl_gene_id: Hden_0524
symbol: Hden_0524
gene_biotype: protein_coding
description:
  RNA polymerase, sigma-24 subunit, ECF subfamily; KEGG: mms:mma_3236 RNA polymerase sigma factor; TIGRFAM: RNA polymerase sigma-70 factor; RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: Hden_0525
symbol: Hden_0525
gene_biotype: protein_coding
description:
  Catalase related subgroup; Has an organic peroxide-dependent peroxidase activity. Belongs to the catalase family.


ensembl_gene_id: Hden_0527
symbol: Hden_0527
gene_biotype: protein_coding
description:
  PFAM: Soluble ligand binding domain; KEGG: nhl:Nhal_2430 respiratory-chain NADH dehydrogenase domain 51 kDa subunit.


ensembl_gene_id: Hden_0529
symbol: Hden_0529
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: xau:Xaut_4699 LysR family transcriptional regulator.


ensembl_gene_id: Hden_0531
symbol: Hden_0531
gene_biotype: protein_coding
description:
  PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; KEGG: sme:SMa0228 glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.


ensembl_gene_id: Hden_0535
symbol: Hden_0535
gene_biotype: protein_coding
description:
  PFAM: NADH:flavin oxidoreductase/NADH oxidase; monooxygenase FAD-binding; KEGG: bph:Bphy_5960 NADH:flavin oxidoreductase/NADH oxidase.


ensembl_gene_id: Hden_0539
symbol: Hden_0539
gene_biotype: protein_coding
description:
  PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel; KEGG: msl:Msil_3605 glycine cleavage T protein (aminomethyl transferase); Belongs to the GcvT family.


ensembl_gene_id: Hden_0540
symbol: Hden_0540
gene_biotype: protein_coding
description:
  KEGG: rhi:NGR_c23520 putative hemin receptor; TIGRFAM: TonB-dependent heme/hemoglobin receptor family protein; PFAM: TonB-dependent receptor; TonB-dependent receptor plug.


ensembl_gene_id: Hden_0541
symbol: Hden_0541
gene_biotype: protein_coding
description:
  PFAM: Antibiotic biosynthesis monooxygenase; KEGG: bph:Bphy_6540 antibiotic biosynthesis monooxygenase.


ensembl_gene_id: Hden_0549
symbol: serC
gene_biotype: protein_coding
description:
  Phosphoserine transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.


ensembl_gene_id: Hden_0551
symbol: pqqE
gene_biotype: protein_coding
description:
  Coenzyme PQQ biosynthesis protein E; Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).


ensembl_gene_id: Hden_0553
symbol: Hden_0553
gene_biotype: protein_coding
description:
  KEGG: psa:PST_2070 hypothetical protein; TIGRFAM: coenzyme PQQ biosynthesis protein A; PFAM: coenzyme PQQ biosynthesis protein A.


ensembl_gene_id: Hden_0554
symbol: Hden_0554
gene_biotype: protein_coding
description:
  PFAM: Beta-ketoacyl synthase; KEGG: nha:Nham_1503 3-oxoacyl-(acyl carrier protein) synthase II; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: Hden_0555
symbol: Hden_0555
gene_biotype: protein_coding
description:
  PFAM: Beta-ketoacyl synthase; KEGG: rpc:RPC_2109 3-oxoacyl-(acyl carrier protein) synthase II; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: Hden_0556
symbol: Hden_0556
gene_biotype: protein_coding
description:
  PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: rec:RHECIAT_CH0002576 probable alcohol dehydrogenase protein.


ensembl_gene_id: Hden_0557
symbol: Hden_0557
gene_biotype: protein_coding
description:
  PFAM: Beta-ketoacyl synthase; KEGG: rpe:RPE_2020 3-oxoacyl-(acyl carrier protein) synthase II; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: Hden_0558
symbol: Hden_0558
gene_biotype: protein_coding
description:
  PFAM: Beta-ketoacyl synthase; KEGG: rpb:RPB_3355 3-oxoacyl-(acyl carrier protein) synthase II; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: Hden_0559
symbol: Hden_0559
gene_biotype: protein_coding
description:
  PFAM: Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA/FabZ; KEGG: nwi:Nwi_1245 3-hydroxymyristoyl-acyl carrier protein dehydratase.


ensembl_gene_id: Hden_0561
symbol: Hden_0561
gene_biotype: protein_coding
description:
  MaoC domain protein dehydratase; KEGG: hoh:Hoch_5030 short-chain dehydrogenase/reductase SDR; manually curated; PFAM: MaoC domain protein dehydratase; short-chain dehydrogenase/reductase SDR.


ensembl_gene_id: Hden_0562
symbol: Hden_0562
gene_biotype: protein_coding
description:
  TIGRFAM: FkbH like protein; HAD-superfamily phosphatase, subfamily IIIC; KEGG: sus:Acid_7156 FkbH like protein.


ensembl_gene_id: Hden_0564
symbol: ubiX
gene_biotype: protein_coding
description:
  3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family.


ensembl_gene_id: Hden_0565
symbol: Hden_0565
gene_biotype: protein_coding
description:
  UbiD family decarboxylase; KEGG: mes:Meso_4293 3-octaprenyl-4hydroxybenzoate decarboxylase; TIGRFAM: UbiD family decarboxylase; PFAM: Carboxylyase-related protein; Belongs to the UbiD family.


ensembl_gene_id: Hden_0570
symbol: Hden_0570
gene_biotype: protein_coding
description:
  Transcriptional regulator, Crp/Fnr family; KEGG: azl:AZL_023730 transcriptional regulator; PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding.


ensembl_gene_id: Hden_0576
symbol: Hden_0576
gene_biotype: protein_coding
description:
  TIGRFAM: oxygen-independent coproporphyrinogen III oxidase; PFAM: HemN domain protein; Radical SAM domain protein; KEGG: rhi:NGR_c09890 HemN coproporphyrinogen III oxidase; SMART: Elongator protein 3/MiaB/NifB; Belongs to the anaerobic coproporphyrinogen-III oxidase family.


ensembl_gene_id: Hden_0580
symbol: Hden_0580
gene_biotype: protein_coding
description:
  PFAM: cytochrome c oxidase subunit III; KEGG: mag:amb2941 heme/copper-type cytochrome/quinol oxidase, subunit 3.


ensembl_gene_id: Hden_0582
symbol: Hden_0582
gene_biotype: protein_coding
description:
  KEGG: azl:AZL_c02070 nitric-oxide reductase, cytochrome b-containing subunit I; PFAM: cytochrome c oxidase subunit I; Belongs to the heme-copper respiratory oxidase family.


ensembl_gene_id: Hden_0583
symbol: Hden_0583
gene_biotype: protein_coding
description:
  PFAM: ATPase associated with various cellular activities AAA_5; CbbQ/NirQ/NorQ domain protein; KEGG: azl:AZL_c02060 nitric-oxide reductase NorQ protein.


ensembl_gene_id: Hden_0584
symbol: Hden_0584
gene_biotype: protein_coding
description:
  Von Willebrand factor type A; KEGG: azl:AZL_c02050 nitric-oxide reductase NorD protein; PFAM: von Willebrand factor type A; SMART: von Willebrand factor type A.


ensembl_gene_id: Hden_0586
symbol: Hden_0586
gene_biotype: protein_coding
description:
  PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: azl:AZL_a08620 iron complex outermembrane recepter protein.


ensembl_gene_id: Hden_0591
symbol: Hden_0591
gene_biotype: protein_coding
description:
  TIGRFAM: nitrite reductase, copper-containing; KEGG: oca:OCAR_7249 copper-containing nitrite reductase; PFAM: multicopper oxidase type 3; Belongs to the multicopper oxidase family.


ensembl_gene_id: Hden_0593
symbol: Hden_0593
gene_biotype: protein_coding
description:
  PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; response regulator receiver; histidine kinase A domain protein; KEGG: rpd:RPD_3277 ATP-binding region, ATPase-like; SMART: ATP-binding region ATPase domain protein; response regulator receiver; PAS domain containing protein; PAC repeat-containing protein; histidine kinase A domain protein.


ensembl_gene_id: Hden_0594
symbol: Hden_0594
gene_biotype: protein_coding
description:
  Two component transcriptional regulator, winged helix family; KEGG: acr:Acry_0577 two component transcriptional regulator; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver.


ensembl_gene_id: Hden_0595
symbol: Hden_0595
gene_biotype: protein_coding
description:
  KEGG: met:M446_0946 Crp/FNR family transcriptional regulator; PFAM: cyclic nucleotide-binding; regulatory protein Crp; SMART: regulatory protein Crp; cyclic nucleotide-binding.


ensembl_gene_id: Hden_0596
symbol: Hden_0596
gene_biotype: protein_coding
description:
  TIGRFAM: PAS sensor protein; PFAM: PAS fold-3 domain protein; PAS fold domain protein; KEGG: mei:Msip34_2466 putative PAS/PAC sensor protein; SMART: PAS domain containing protein; PAC repeat-containing protein.


ensembl_gene_id: Hden_0597
symbol: Hden_0597
gene_biotype: protein_coding
description:
  Signal transduction histidine kinase, nitrate/nitrite-specific, NarQ; KEGG: mei:Msip34_2465 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation and phosphoacceptor region; SMART: ATP-binding region ATPase domain protein.


ensembl_gene_id: Hden_0598
symbol: Hden_0598
gene_biotype: protein_coding
description:
  KEGG: mei:Msip34_2464 two component transcriptional regulator, LuxR family; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR.


ensembl_gene_id: Hden_0599
symbol: Hden_0599
gene_biotype: protein_coding
description:
  Radical SAM domain protein; KEGG: cko:CKO_02656 coproporphyrinogen III oxidase; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB.


ensembl_gene_id: Hden_0601
symbol: Hden_0601
gene_biotype: protein_coding
description:
  PFAM: NAD-dependent epimerase/dehydratase; KEGG: hha:Hhal_0382 NAD-dependent epimerase/dehydratase family protein.


ensembl_gene_id: Hden_0602
symbol: Hden_0602
gene_biotype: protein_coding
description:
  TIGRFAM: PAS sensor protein; PFAM: chemotaxis sensory transducer; PAS fold-3 domain protein; KEGG: cak:Caul_1141 methyl-accepting chemotaxis sensory transducer with PAS/Pac sensor; SMART: chemotaxis sensory transducer; PAS domain containing protein; PAC repeat-containing protein; histidine kinase HAMP region domain protein.


ensembl_gene_id: Hden_0603
symbol: Hden_0603
gene_biotype: protein_coding
description:
  CheW protein; KEGG: smd:Smed_0236 putative CheW protein; PFAM: CheW domain protein; SMART: CheW domain protein.


ensembl_gene_id: Hden_0606
symbol: cynS
gene_biotype: protein_coding
description:
  Cyanate lyase; Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide; Belongs to the cyanase family.


ensembl_gene_id: Hden_0607
symbol: Hden_0607
gene_biotype: protein_coding
description:
  D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.


ensembl_gene_id: Hden_0608
symbol: Hden_0608
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: msl:Msil_2452 transcriptional regulator, LysR family.


ensembl_gene_id: Hden_0609
symbol: Hden_0609
gene_biotype: protein_coding
description:
  Sigma54 specific transcriptional regulator, Fis family; Manually curated; PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; globin; KEGG: mrd:Mrad2831_4540 fis family transcriptional regulator; SMART: AAA ATPase.


ensembl_gene_id: Hden_0613
symbol: ilvD
gene_biotype: protein_coding
description:
  PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; manually curated; KEGG: bmr:BMI_I102 dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.


ensembl_gene_id: Hden_0614
symbol: Hden_0614
gene_biotype: protein_coding
description:
  KEGG: oca:OCAR_5762 serine-type D-Ala-D-Ala carboxypeptidase; PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; Sporulation domain protein; Belongs to the peptidase S11 family.


ensembl_gene_id: Hden_0616
symbol: clpS
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease adaptor protein ClpS; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family.


ensembl_gene_id: Hden_0617
symbol: Hden_0617
gene_biotype: protein_coding
description:
  TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: ATPase AAA-2 domain protein; AAA ATPase central domain protein; Clp domain protein; Clp ATPase-like; KEGG: azc:AZC_1595 AAA ATPase; SMART: AAA ATPase; Belongs to the ClpA/ClpB family.


ensembl_gene_id: Hden_0621
symbol: Hden_0621
gene_biotype: protein_coding
description:
  PFAM: glycerophosphoryl diester phosphodiesterase; KEGG: xau:Xaut_3792 glycerophosphoryl diester phosphodiesterase.


ensembl_gene_id: Hden_0625
symbol: Hden_0625
gene_biotype: protein_coding
description:
  KEGG: mmr:Mmar10_1276 response regulator receiver protein; PFAM: response regulator receiver; SMART: response regulator receiver.


ensembl_gene_id: Hden_0626
symbol: Hden_0626
gene_biotype: protein_coding
description:
  TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; response regulator receiver; KEGG: rpb:RPB_2413 response regulator PleD; SMART: GGDEF domain containing protein; response regulator receiver.


ensembl_gene_id: Hden_0627
symbol: rpmG
gene_biotype: protein_coding
description:
  KEGG: sjp:SJA_C1-01020 ribosomal protein L33; TIGRFAM: ribosomal protein L33; PFAM: ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family.


ensembl_gene_id: Hden_0630
symbol: rnr
gene_biotype: protein_coding
description:
  Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.


ensembl_gene_id: Hden_0631
symbol: topA
gene_biotype: protein_coding
description:
  DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]


ensembl_gene_id: Hden_0633
symbol: Hden_0633
gene_biotype: protein_coding
description:
  KEGG: nha:Nham_2285 DNA processing protein DprA, putative; TIGRFAM: DNA protecting protein DprA; PFAM: SMF family protein.


ensembl_gene_id: Hden_0634
symbol: plsY
gene_biotype: protein_coding
description:
  Protein of unknown function DUF205; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.


ensembl_gene_id: Hden_0635
symbol: Hden_0635
gene_biotype: protein_coding
description:
  KEGG: mno:Mnod_3311 dihydroorotase, multifunctional complex type; TIGRFAM: dihydroorotase, multifunctional complex type; PFAM: amidohydrolase.


ensembl_gene_id: Hden_0636
symbol: pyrB
gene_biotype: protein_coding
description:
  TIGRFAM: aspartate carbamoyltransferase; KEGG: pla:Plav_2836 aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.


ensembl_gene_id: Hden_0637
symbol: Hden_0637
gene_biotype: protein_coding
description:
  Holliday junction resolvase YqgF; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family.


ensembl_gene_id: Hden_0638
symbol: gatC
gene_biotype: protein_coding
description:
  glutamyl-tRNA(Gln) amidotransferase, C subunit; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family.


ensembl_gene_id: Hden_0640
symbol: gatA
gene_biotype: protein_coding
description:
  glutamyl-tRNA(Gln) amidotransferase, A subunit; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln).


ensembl_gene_id: Hden_0641
symbol: Hden_0641
gene_biotype: protein_coding
description:
  Chorismate mutase, type II; KEGG: oca:OCAR_5798 T-protein; PFAM: Chorismate mutase, type II; SMART: Chorismate mutase.


ensembl_gene_id: Hden_0643
symbol: gatB
gene_biotype: protein_coding
description:
  glutamyl-tRNA(Gln) amidotransferase, B subunit; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily.


ensembl_gene_id: Hden_0649
symbol: Hden_0649
gene_biotype: protein_coding
description:
  PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: mms:mma_0551 NADPH2:quinone reductase.


ensembl_gene_id: Hden_0650
symbol: Hden_0650
gene_biotype: protein_coding
description:
  PFAM: Glutathione S-transferase domain; KEGG: xau:Xaut_3798 glutathione S-transferase domain-containing protein; Belongs to the GST superfamily.


ensembl_gene_id: Hden_0652
symbol: Hden_0652
gene_biotype: protein_coding
description:
  PFAM: Sel1 domain protein repeat-containing protein; KEGG: pla:Plav_2849 Sel1 domain-containing protein.


ensembl_gene_id: Hden_0668
symbol: Hden_0668
gene_biotype: protein_coding
description:
  KEGG: met:M446_3983 integrase family protein; manually curated; PFAM: integrase family protein; Belongs to the 'phage' integrase family.


ensembl_gene_id: Hden_0671
symbol: Hden_0671
gene_biotype: protein_coding
description:
  KEGG: bra:BRADO4915 putative threonine-phosphate decarboxylase; TIGRFAM: L-threonine-O-3-phosphate decarboxylase; PFAM: aminotransferase class I and II.


ensembl_gene_id: Hden_0672
symbol: Hden_0672
gene_biotype: protein_coding
description:
  PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: rpa:RPA0765 putative outer membrane receptor for iron transport.


ensembl_gene_id: Hden_0674
symbol: Hden_0674
gene_biotype: protein_coding
description:
  PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: pde:Pden_4168 binding-protein-dependent transport systems inner membrane component.


ensembl_gene_id: Hden_0682
symbol: Hden_0682
gene_biotype: protein_coding
description:
  Transcriptional regulator, ArsR family; KEGG: rpd:RPD_4201 regulatory protein, ArsR; PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR.


ensembl_gene_id: Hden_0683
symbol: Hden_0683
gene_biotype: protein_coding
description:
  KEGG: tgr:Tgr7_2207 radical SAM domain protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB.


ensembl_gene_id: Hden_0684
symbol: Hden_0684
gene_biotype: protein_coding
description:
  KEGG: tgr:Tgr7_2205 geranylgeranyl reductase; TIGRFAM: geranylgeranyl reductase; PFAM: monooxygenase FAD-binding.


ensembl_gene_id: Hden_0685
symbol: Hden_0685
gene_biotype: protein_coding
description:
  KEGG: tkm:TK90_0644 radical SAM domain protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB.


ensembl_gene_id: Hden_0690
symbol: Hden_0690
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; KEGG: afr:AFE_2586 heterodisulfide reductase subunit B, homolog.


ensembl_gene_id: Hden_0691
symbol: Hden_0691
gene_biotype: protein_coding
description:
  PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; KEGG: tgr:Tgr7_2214 FAD-dependent pyridine nucleotide-disulphide oxidoreductase.


ensembl_gene_id: Hden_0694
symbol: Hden_0694
gene_biotype: protein_coding
description:
  KEGG: tgr:Tgr7_2211 CoB--CoM heterodisulfide reductase; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein.


ensembl_gene_id: Hden_0698
symbol: Hden_0698
gene_biotype: protein_coding
description:
  PFAM: SirA family protein; KEGG: mag:amb0858 redox protein; Belongs to the sulfur carrier protein TusA family.


ensembl_gene_id: Hden_0699
symbol: Hden_0699
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF395 YeeE/YedE; KEGG: xau:Xaut_1528 protein of unknown function DUF395 YeeE/YedE.


ensembl_gene_id: Hden_0700
symbol: Hden_0700
gene_biotype: protein_coding
description:
  Transcriptional regulator, ArsR family; KEGG: xau:Xaut_1527 regulatory protein ArsR; PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR.


ensembl_gene_id: Hden_0706
symbol: Hden_0706
gene_biotype: protein_coding
description:
  PFAM: 5'-Nucleotidase domain protein; KEGG: bja:blr3515 Mn-dependent hydrolase; Belongs to the 5'-nucleotidase family.


ensembl_gene_id: Hden_0710
symbol: Hden_0710
gene_biotype: protein_coding
description:
  DNA binding domain protein, excisionase family; KEGG: mdi:METDI2655 transcriptional repressor of DCM dehalogenase; TIGRFAM: DNA binding domain protein, excisionase family; PFAM: regulatory protein MerR.


ensembl_gene_id: Hden_0711
symbol: Hden_0711
gene_biotype: protein_coding
description:
  PFAM: Glutathione S-transferase domain; KEGG: mdi:METDI2656 dichloromethane dehalogenase (DCM dehalogenase).


ensembl_gene_id: Hden_0717
symbol: Hden_0717
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: pca:Pcar_2639 LysR family transcriptional regulator.


ensembl_gene_id: Hden_0718
symbol: Hden_0718
gene_biotype: protein_coding
description:
  PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: reu:Reut_B3588 hypothetical protein.


ensembl_gene_id: Hden_0722
symbol: Hden_0722
gene_biotype: protein_coding
description:
  Two component transcriptional regulator, LuxR family; KEGG: bja:blr6185 two-component response regulator; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR.


ensembl_gene_id: Hden_0725
symbol: Hden_0725
gene_biotype: protein_coding
description:
  KEGG: alv:Alvin_0640 two component transcriptional regulator, LuxR family; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR.


ensembl_gene_id: Hden_0726
symbol: Hden_0726
gene_biotype: protein_coding
description:
  Multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; GAF domain protein; KEGG: mag:amb0896 C4-dicarboxylate transport sensor protein DctS; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; PAC repeat-containing protein; GAF domain protein.


ensembl_gene_id: Hden_0730
symbol: azoR
gene_biotype: protein_coding
description:
  NAD(P)H dehydrogenase (quinone); Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity; Belongs to the azoreductase type 1 family.


ensembl_gene_id: Hden_0731
symbol: Hden_0731
gene_biotype: protein_coding
description:
  Peroxidase; KEGG: gbe:GbCGDNIH1_0908 peroxidase; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Peroxiredoxin-like.


ensembl_gene_id: Hden_0734
symbol: Hden_0734
gene_biotype: protein_coding
description:
  PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; ferredoxin; Oxidoreductase FAD-binding domain protein; KEGG: pmy:Pmen_2542 oxidoreductase FAD/NAD(P)-binding subunit.


ensembl_gene_id: Hden_0735
symbol: Hden_0735
gene_biotype: protein_coding
description:
  Ferric uptake regulator, Fur family; PFAM: ferric-uptake regulator; KEGG: mch:Mchl_0456 ferric uptake regulator, Fur family; Belongs to the Fur family.


ensembl_gene_id: Hden_0737
symbol: Hden_0737
gene_biotype: protein_coding
description:
  PFAM: alpha/beta hydrolase fold; KEGG: msl:Msil_2478 hypothetical protein; Belongs to the AB hydrolase superfamily. MetX family.


ensembl_gene_id: Hden_0739
symbol: Hden_0739
gene_biotype: protein_coding
description:
  KEGG: mms:mma_2479 hypothetical protein; PFAM: flavin reductase domain protein FMN-binding; SMART: flavin reductase domain protein FMN-binding.


ensembl_gene_id: Hden_0741
symbol: Hden_0741
gene_biotype: protein_coding
description:
  Cytochrome-c peroxidase; KEGG: mca:MCA0318 SCO1/SenC family protein/methylamine utilization protein MauG, putative; PFAM: Di-haem cytochrome c peroxidase.


ensembl_gene_id: Hden_0742
symbol: Hden_0742
gene_biotype: protein_coding
description:
  PFAM: electron transport protein SCO1/SenC; KEGG: mca:MCA0318 SCO1/SenC family protein/methylamine utilization protein MauG, putative.


ensembl_gene_id: Hden_0745
symbol: Hden_0745
gene_biotype: protein_coding
description:
  Alkylhydroperoxidase like protein, AhpD family; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.


ensembl_gene_id: Hden_0746
symbol: Hden_0746
gene_biotype: protein_coding
description:
  PFAM: TonB-dependent receptor plug; TonB-dependent receptor; KEGG: mes:Meso_2063 TonB-dependent receptor.


ensembl_gene_id: Hden_0751
symbol: dinB
gene_biotype: protein_coding
description:
  DNA-directed DNA polymerase; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.


ensembl_gene_id: Hden_0755
symbol: dnaE2
gene_biotype: protein_coding
description:
  DNA polymerase III, alpha subunit; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.


ensembl_gene_id: Hden_0756
symbol: Hden_0756
gene_biotype: protein_coding
description:
  KEGG: azo:azo1336 putative sulfate transport system substrate-binding protein; TIGRFAM: sulfate ABC transporter, periplasmic sulfate-binding protein; PFAM: extracellular solute-binding protein family 1.


ensembl_gene_id: Hden_0759
symbol: Hden_0759
gene_biotype: protein_coding
description:
  KEGG: bxe:Bxe_B1552 cysteine desulphurases, SufS; TIGRFAM: cysteine desulfurase, SufS subfamily; PFAM: aminotransferase class V; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: Hden_0763
symbol: Hden_0763
gene_biotype: protein_coding
description:
  KEGG: bid:Bind_3835 MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor; PFAM: HWE histidine kinase; MCP methyltransferase CheR-type; PAS fold-4 domain protein; CheB methylesterase; SMART: MCP methyltransferase CheR-type; PAC repeat-containing protein; PAS domain containing protein.


ensembl_gene_id: Hden_0764
symbol: Hden_0764
gene_biotype: protein_coding
description:
  Putative transcriptional regulator, Crp/Fnr family; SMART: cyclic nucleotide-binding; KEGG: met:M446_1834 cyclic nucleotide-binding protein.


ensembl_gene_id: Hden_0770
symbol: Hden_0770
gene_biotype: protein_coding
description:
  KEGG: rle:RL3714 putative phytochrome/sensor histidine kinase; PFAM: HWE histidine kinase; GAF domain protein; PAS fold-2 domain protein; Phytochrome central region domain protein; response regulator receiver; SMART: response regulator receiver; GAF domain protein.


ensembl_gene_id: Hden_0775
symbol: Hden_0775
gene_biotype: protein_coding
description:
  TIGRFAM: glutamine synthetase, type III; KEGG: mlo:mlr6210 glutamine synthetase III; PFAM: glutamine synthetase catalytic region.


ensembl_gene_id: Hden_0777
symbol: Hden_0777
gene_biotype: protein_coding
description:
  PFAM: glutamate synthase alpha subunit domain protein; KEGG: mch:Mchl_1939 glutamate synthase alpha subunit domain protein.


ensembl_gene_id: Hden_0778
symbol: Hden_0778
gene_biotype: protein_coding
description:
  PFAM: ferredoxin-dependent glutamate synthase; KEGG: mei:Msip34_2421 ferredoxin-dependent glutamate synthase; Belongs to the glutamate synthase family.


ensembl_gene_id: Hden_0779
symbol: Hden_0779
gene_biotype: protein_coding
description:
  KEGG: tgr:Tgr7_1702 transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; Cupin 2 conserved barrel domain protein; SMART: helix-turn-helix domain protein.


ensembl_gene_id: Hden_0780
symbol: Hden_0780
gene_biotype: protein_coding
description:
  PFAM: amino acid permease-associated region; KEGG: smd:Smed_3317 amino acid permease-associated region.


ensembl_gene_id: Hden_0781
symbol: Hden_0781
gene_biotype: protein_coding
description:
  PFAM: extracellular solute-binding protein family 3; KEGG: msl:Msil_3735 extracellular solute-binding protein family 3.


ensembl_gene_id: Hden_0783
symbol: Hden_0783
gene_biotype: protein_coding
description:
  PQQ-dependent enzyme-like protein; KEGG: azo:azo3865 putative quinoprotein ethanol dehydrogenase; PFAM: PQQ-dependent enzyme-like; Pyrrolo-quinoline quinone; SMART: Pyrrolo-quinoline quinone beta-propeller repeat.


ensembl_gene_id: Hden_0785
symbol: Hden_0785
gene_biotype: protein_coding
description:
  KEGG: bid:Bind_0120 transketolase central region; PFAM: Transketolase central region; Transketolase domain protein; SMART: Transketolase central region.


ensembl_gene_id: Hden_0786
symbol: Hden_0786
gene_biotype: protein_coding
description:
  PFAM: alpha/beta hydrolase fold; biotin/lipoyl attachment domain-containing protein; KEGG: gdj:Gdia_3501 branched-chain alpha-keto acid dehydrogenase subunit E2.


ensembl_gene_id: Hden_0787
symbol: Hden_0787
gene_biotype: protein_coding
description:
  KEGG: xau:Xaut_4046 fis family GAF modulated sigma54 specific transcriptional regulator; PFAM: sigma-54 factor interaction domain-containing protein; GAF domain protein; helix-turn-helix Fis-type; SMART: AAA ATPase.


ensembl_gene_id: Hden_0788
symbol: thiG
gene_biotype: protein_coding
description:
  Thiazole biosynthesis family protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.


ensembl_gene_id: Hden_0789
symbol: Hden_0789
gene_biotype: protein_coding
description:
  KEGG: rde:RD1_0748 thiamine biosynthesis protein ThiS, putative; TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein.


ensembl_gene_id: Hden_0791
symbol: Hden_0791
gene_biotype: protein_coding
description:
  Manually curated; TIGRFAM: dihydrolipoamide dehydrogenase; KEGG: mpo:Mpop_2913 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region.


ensembl_gene_id: Hden_0794
symbol: thiC
gene_biotype: protein_coding
description:
  Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.


ensembl_gene_id: Hden_0796
symbol: Hden_0796
gene_biotype: protein_coding
description:
  TIGRFAM: PQQ-dependent dehydrogenase, methanol/ethanol family; PFAM: PQQ-dependent enzyme-like; Pyrrolo-quinoline quinone; KEGG: mpt:Mpe_A1591 putative quinoprotein ethanol dehydrogenase precursor; SMART: Pyrrolo-quinoline quinone beta-propeller repeat.


ensembl_gene_id: Hden_0798
symbol: Hden_0798
gene_biotype: protein_coding
description:
  KEGG: rlg:Rleg_2200 transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein.


ensembl_gene_id: Hden_0799
symbol: Hden_0799
gene_biotype: protein_coding
description:
  KEGG: rlt:Rleg2_1990 efflux transporter, RND family, MFP subunit; TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: Hden_0803
symbol: Hden_0803
gene_biotype: protein_coding
description:
  KEGG: msl:Msil_0811 3-hydroxybutyrate dehydrogenase; TIGRFAM: 3-hydroxybutyrate dehydrogenase; PFAM: short-chain dehydrogenase/reductase SDR.


ensembl_gene_id: Hden_0806
symbol: Hden_0806
gene_biotype: protein_coding
description:
  KEGG: aav:Aave_2157 TetR family transcriptional regulator; manually curated; PFAM: regulatory protein TetR.


ensembl_gene_id: Hden_0807
symbol: Hden_0807
gene_biotype: protein_coding
description:
  PFAM: major facilitator superfamily MFS_1; KEGG: aav:Aave_2158 major facilitator superfamily transporter.


ensembl_gene_id: Hden_0808
symbol: Hden_0808
gene_biotype: protein_coding
description:
  Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.


ensembl_gene_id: Hden_0809
symbol: Hden_0809
gene_biotype: protein_coding
description:
  Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.


ensembl_gene_id: Hden_0810
symbol: Hden_0810
gene_biotype: protein_coding
description:
  TIGRFAM: 2-methylcitrate synthase/citrate synthase II; KEGG: pde:Pden_1347 methylcitrate synthase; PFAM: Citrate synthase; Belongs to the citrate synthase family.


ensembl_gene_id: Hden_0812
symbol: Hden_0812
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: bur:Bcep18194_B2817 DNA-binding transcriptional regulator CynR.


ensembl_gene_id: Hden_0814
symbol: Hden_0814
gene_biotype: protein_coding
description:
  KEGG: mpo:Mpop_3828 two component transcriptional regulator, LuxR family; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR.


ensembl_gene_id: Hden_0815
symbol: Hden_0815
gene_biotype: protein_coding
description:
  KEGG: mpo:Mpop_3827 integral membrane sensor signal transduction histidine kinase; PFAM: histidine kinase dimerisation and phosphoacceptor region; histidine kinase HAMP region domain protein; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein.


ensembl_gene_id: Hden_0818
symbol: Hden_0818
gene_biotype: protein_coding
description:
  KEGG: azl:AZL_009970 methyl-accepting chemotaxis protein; PFAM: chemotaxis sensory transducer; SMART: chemotaxis sensory transducer.


ensembl_gene_id: Hden_0823
symbol: rlmE
gene_biotype: protein_coding
description:
  Ribosomal RNA methyltransferase RrmJ/FtsJ; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.


ensembl_gene_id: Hden_0825
symbol: guaB
gene_biotype: protein_coding
description:
  Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.


ensembl_gene_id: Hden_0827
symbol: Hden_0827
gene_biotype: protein_coding
description:
  PFAM: Fmu (Sun) domain protein; KEGG: mlo:mlr6944 SUN-family protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.


ensembl_gene_id: Hden_0835
symbol: Hden_0835
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: oca:OCAR_7550 transcriptional regulator of LysR family.


ensembl_gene_id: Hden_0836
symbol: aat
gene_biotype: protein_coding
description:
  leucyl/phenylalanyl-tRNA/protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.


ensembl_gene_id: Hden_0837
symbol: Hden_0837
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.


ensembl_gene_id: Hden_0838
symbol: Hden_0838
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.


ensembl_gene_id: Hden_0839
symbol: aroQ
gene_biotype: protein_coding
description:
  3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.


ensembl_gene_id: Hden_0841
symbol: Hden_0841
gene_biotype: protein_coding
description:
  PFAM: peptidase M48 Ste24p; Tetratricopeptide TPR_2 repeat protein; KEGG: bja:bll4295 hypothetical protein.


ensembl_gene_id: Hden_0842
symbol: rne
gene_biotype: protein_coding
description:
  Ribonuclease, Rne/Rng family; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily.


ensembl_gene_id: Hden_0843
symbol: Hden_0843
gene_biotype: protein_coding
description:
  Cell wall hydrolase/autolysin; KEGG: rpe:RPE_2978 N-acetylmuramoyl-L-alanine amidase; PFAM: cell wall hydrolase/autolysin; SMART: cell wall hydrolase/autolysin.


ensembl_gene_id: Hden_0844
symbol: Hden_0844
gene_biotype: protein_coding
description:
  TIGRFAM: penicillin-binding protein, 1A family; KEGG: azc:AZC_3625 penicillin-binding protein 1A precursor; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase.


ensembl_gene_id: Hden_0845
symbol: prfB
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.


ensembl_gene_id: Hden_0847
symbol: Hden_0847
gene_biotype: protein_coding
description:
  Hypothetical protein; KEGG: gyc:GYMC61_3110 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, HpaG1 subunit.


ensembl_gene_id: Hden_0849
symbol: Hden_0849
gene_biotype: protein_coding
description:
  PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: tRNA/rRNA methyltransferase SpoU; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.


ensembl_gene_id: Hden_0854
symbol: Hden_0854
gene_biotype: protein_coding
description:
  PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: bbt:BBta_3881 putative ErfK/YbiS/YcfS/YnhG family protein.


ensembl_gene_id: Hden_0855
symbol: panB
gene_biotype: protein_coding
description:
  3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.


ensembl_gene_id: Hden_0858
symbol: der
gene_biotype: protein_coding
description:
  Ribosome-associated GTPase EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.


ensembl_gene_id: Hden_0861
symbol: rlmJ
gene_biotype: protein_coding
description:
  Protein of unknown function DUF519; Specifically methylates the adenine in position 2030 of 23S rRNA.


ensembl_gene_id: Hden_0862
symbol: Hden_0862
gene_biotype: protein_coding
description:
  KEGG: bid:Bind_0662 cold-shock DNA-binding domain-containing protein; PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein.


ensembl_gene_id: Hden_0867
symbol: Hden_0867
gene_biotype: protein_coding
description:
  KEGG: mno:Mnod_1693 response regulator receiver protein; PFAM: response regulator receiver; SMART: response regulator receiver.


ensembl_gene_id: Hden_0869
symbol: cysQ
gene_biotype: protein_coding
description:
  Inositol monophosphatase; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family.


ensembl_gene_id: Hden_0872
symbol: Hden_0872
gene_biotype: protein_coding
description:
  KEGG: oca:OCAR_4913 cation diffusion facilitator family transporter; TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein.


ensembl_gene_id: Hden_0873
symbol: Hden_0873
gene_biotype: protein_coding
description:
  Putative transcriptional regulator, Crp/Fnr family; KEGG: bme:BMEI1294 nitrogen fixation regulation protein FixK; PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding.


ensembl_gene_id: Hden_0878
symbol: Hden_0878
gene_biotype: protein_coding
description:
  PFAM: transport system permease protein; KEGG: mrd:Mrad2831_4589 transport system permease protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: Hden_0880
symbol: Hden_0880
gene_biotype: protein_coding
description:
  KEGG: sti:Sthe_0732 rhodanese domain protein; PFAM: Rhodanese domain protein; SMART: Rhodanese domain protein.


ensembl_gene_id: Hden_0888
symbol: Hden_0888
gene_biotype: protein_coding
description:
  PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; KEGG: emi:Emin_0863 DegT/DnrJ/EryC1/StrS aminotransferase; Belongs to the DegT/DnrJ/EryC1 family.


ensembl_gene_id: Hden_0894
symbol: Hden_0894
gene_biotype: protein_coding
description:
  2-oxo-acid dehydrogenase E1 subunit, homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


ensembl_gene_id: Hden_0895
symbol: Hden_0895
gene_biotype: protein_coding
description:
  PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain-containing protein; E3 binding domain protein; KEGG: met:M446_6300 dehydrogenase catalytic domain-containing protein.


ensembl_gene_id: Hden_0896
symbol: Hden_0896
gene_biotype: protein_coding
description:
  KEGG: bmj:BMULJ_02119 dihydrolipoamide dehydrogenase; TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region.


ensembl_gene_id: Hden_0900
symbol: Hden_0900
gene_biotype: protein_coding
description:
  Putative RNA polymerase, sigma-24 subunit, ECF subfamily; KEGG: xau:Xaut_4187 RNA polymerase ECF-subfamily sigma factor; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2.


ensembl_gene_id: Hden_0905
symbol: Hden_0905
gene_biotype: protein_coding
description:
  Manually curated; TIGRFAM: RNA methyltransferase, TrmH family, group 3; KEGG: rpe:RPE_3682 RNA methyltransferase; PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase substrate binding; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.


ensembl_gene_id: Hden_0906
symbol: Hden_0906
gene_biotype: protein_coding
description:
  PFAM: integrase family protein; KEGG: met:M446_2924 integrase family protein; Belongs to the 'phage' integrase family.


ensembl_gene_id: Hden_0907
symbol: Hden_0907
gene_biotype: protein_coding
description:
  KEGG: hla:Hlac_3437 helicase domain protein; PFAM: helicase domain protein; SNF2-related protein; SMART: DEAD-like helicase; helicase domain protein.


ensembl_gene_id: Hden_0910
symbol: Hden_0910
gene_biotype: protein_coding
description:
  Resolvase domain protein; KEGG: plt:Plut_0854 invertase/recombinase like protein; PFAM: Resolvase domain; SMART: Resolvase domain.


ensembl_gene_id: Hden_0915
symbol: Hden_0915
gene_biotype: protein_coding
description:
  Two component transcriptional regulator, LuxR family; KEGG: bja:bll2759 response regulator FixJ; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR.


ensembl_gene_id: Hden_0916
symbol: Hden_0916
gene_biotype: protein_coding
description:
  Integral membrane sensor signal transduction histidine kinase; KEGG: azl:AZL_c01170 two-component sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; MASE1 domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein.


ensembl_gene_id: Hden_0917
symbol: Hden_0917
gene_biotype: protein_coding
description:
  Acriflavin resistance protein; KEGG: gvi:gll0876 AcrB/AcrD/AcrF family multidrug efflux protein; manually curated; PFAM: acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: Hden_0918
symbol: Hden_0918
gene_biotype: protein_coding
description:
  KEGG: bcj:BCAS0583 efflux system transport protein; TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: Hden_0919
symbol: Hden_0919
gene_biotype: protein_coding
description:
  KEGG: esa:ESA_02519 hypothetical protein; TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein.


ensembl_gene_id: Hden_0920
symbol: Hden_0920
gene_biotype: protein_coding
description:
  KEGG: ana:alr1677 hypothetical protein; PFAM: TPR repeat-containing protein; SMART: Tetratricopeptide repeat.


ensembl_gene_id: Hden_0925
symbol: Hden_0925
gene_biotype: protein_coding
description:
  KEGG: azc:AZC_1424 nitrite extrusion protein; TIGRFAM: nitrite transporter; PFAM: major facilitator superfamily MFS_1.


ensembl_gene_id: Hden_0926
symbol: Hden_0926
gene_biotype: protein_coding
description:
  KEGG: azc:AZC_1425 nitrate reductase alpha subunit protein; TIGRFAM: nitrate reductase, alpha subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: Hden_0927
symbol: Hden_0927
gene_biotype: protein_coding
description:
  TIGRFAM: nitrate reductase, beta subunit; KEGG: azc:AZC_1426 nitrate reductase beta subunit protein.


ensembl_gene_id: Hden_0928
symbol: Hden_0928
gene_biotype: protein_coding
description:
  TIGRFAM: nitrate reductase molybdenum cofactor assembly chaperone; KEGG: azc:AZC_1427 nitrate reductase delta subunit protein; PFAM: Nitrate reductase delta subunit.


ensembl_gene_id: Hden_0929
symbol: Hden_0929
gene_biotype: protein_coding
description:
  TIGRFAM: respiratory nitrate reductase, gamma subunit; KEGG: azc:AZC_1428 nitrate reductase gamma subunit protein; PFAM: Nitrate reductase gamma subunit.


ensembl_gene_id: Hden_0930
symbol: Hden_0930
gene_biotype: protein_coding
description:
  PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: azc:AZC_1429 putative peptidyl-prolyl cis-trans isomerase.


ensembl_gene_id: Hden_0936
symbol: Hden_0936
gene_biotype: protein_coding
description:
  PFAM: acriflavin resistance protein; KEGG: nwi:Nwi_1521 acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: Hden_0937
symbol: Hden_0937
gene_biotype: protein_coding
description:
  PFAM: acriflavin resistance protein; KEGG: bja:blr4457 AcrB/AcrD/AcrF family protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: Hden_0938
symbol: Hden_0938
gene_biotype: protein_coding
description:
  KEGG: ara:Arad_4549 secretion protein HlyD; TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: Hden_0939
symbol: Hden_0939
gene_biotype: protein_coding
description:
  TIGRFAM: diguanylate cyclase; PFAM: EAL domain protein; GGDEF domain containing protein; KEGG: bra:BRADO2968 hypothetical protein; SMART: EAL domain protein; GGDEF domain containing protein.


ensembl_gene_id: Hden_0940
symbol: Hden_0940
gene_biotype: protein_coding
description:
  TIGRFAM: methionine-R-sulfoxide reductase; KEGG: dac:Daci_3070 methionine-R-sulfoxide reductase; PFAM: Methionine sulfoxide reductase B.


ensembl_gene_id: Hden_0941
symbol: sfsA
gene_biotype: protein_coding
description:
  KEGG: pzu:PHZ_c1072 sugar fermentation stimulation protein A; TIGRFAM: sugar fermentation stimulation protein; PFAM: sugar fermentation stimulation protein; Belongs to the SfsA family.


ensembl_gene_id: Hden_0948
symbol: Hden_0948
gene_biotype: protein_coding
description:
  PFAM: Excinuclease ABC C subunit domain protein; KEGG: cpc:Cpar_1954 excinuclease ABC C subunit domain protein.


ensembl_gene_id: Hden_0950
symbol: Hden_0950
gene_biotype: protein_coding
description:
  Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.


ensembl_gene_id: Hden_0951
symbol: Hden_0951
gene_biotype: protein_coding
description:
  PFAM: NADH:ubiquinone oxidoreductase 17.2 kD subunit; KEGG: pla:Plav_3297 NADH:ubiquinone oxidoreductase 17.2 kD subunit.


ensembl_gene_id: Hden_0953
symbol: Hden_0953
gene_biotype: protein_coding
description:
  Porphobilinogen synthase; KEGG: pla:Plav_2897 delta-aminolevulinic acid dehydratase; PFAM: delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.


ensembl_gene_id: Hden_0954
symbol: Hden_0954
gene_biotype: protein_coding
description:
  PFAM: ErfK/YbiS/YcfS/YnhG family protein; Peptidoglycan-binding domain 1 protein; KEGG: bid:Bind_0884 peptidoglycan binding domain-containing protein.


ensembl_gene_id: Hden_0955
symbol: Hden_0955
gene_biotype: protein_coding
description:
  Transcriptional regulator, MarR family; KEGG: sme:SMc01768 putative transcription regulator protein; PFAM: regulatory protein MarR; SMART: regulatory protein MarR.


ensembl_gene_id: Hden_0959
symbol: Hden_0959
gene_biotype: protein_coding
description:
  TIGRFAM: 5-aminolevulinic acid synthase; KEGG: msl:Msil_2030 5-aminolevulinate synthase; PFAM: aminotransferase class I and II.


ensembl_gene_id: Hden_0960
symbol: glyA
gene_biotype: protein_coding
description:
  Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.


ensembl_gene_id: Hden_0961
symbol: nrdR
gene_biotype: protein_coding
description:
  ATP-cone domain protein; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.


ensembl_gene_id: Hden_0962
symbol: Hden_0962
gene_biotype: protein_coding
description:
  Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.


ensembl_gene_id: Hden_0963
symbol: Hden_0963
gene_biotype: protein_coding
description:
  TIGRFAM: riboflavin synthase, alpha subunit; KEGG: azl:AZL_010170 riboflavin synthase alpha chain; PFAM: Lumazine-binding protein.


ensembl_gene_id: Hden_0964
symbol: ribB
gene_biotype: protein_coding
description:
  3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.


ensembl_gene_id: Hden_0965
symbol: ribH
gene_biotype: protein_coding
description:
  6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.


ensembl_gene_id: Hden_0966
symbol: nusB
gene_biotype: protein_coding
description:
  NusB antitermination factor; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.


ensembl_gene_id: Hden_0967
symbol: thiL
gene_biotype: protein_coding
description:
  Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.


ensembl_gene_id: Hden_0968
symbol: Hden_0968
gene_biotype: protein_coding
description:
  PFAM: ErfK/YbiS/YcfS/YnhG family protein; Peptidoglycan-binding domain 1 protein; KEGG: msl:Msil_2112 ErfK/YbiS/YcfS/YnhG family protein.


ensembl_gene_id: Hden_0969
symbol: Hden_0969
gene_biotype: protein_coding
description:
  Transcriptional regulator, AsnC family; KEGG: bja:bll3178 transcriptional regulatory protein; PFAM: Transcription regulator, AsnC-type-like; SMART: Transcription regulator, AsnC-type.


ensembl_gene_id: Hden_0970
symbol: Hden_0970
gene_biotype: protein_coding
description:
  TIGRFAM: alanine dehydrogenase; KEGG: sme:SMc01169 alanine dehydrogenase oxidoreductase protein; PFAM: alanine dehydrogenase/PNT domain protein; Belongs to the AlaDH/PNT family.


ensembl_gene_id: Hden_0971
symbol: Hden_0971
gene_biotype: protein_coding
description:
  KEGG: sme:SMc01534 omega amino acid--pyruvate transaminase; PFAM: aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: Hden_0972
symbol: Hden_0972
gene_biotype: protein_coding
description:
  KEGG: azl:AZL_c00280 4-aminobutyrate aminotransferase; TIGRFAM: 4-aminobutyrate aminotransferase; PFAM: aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: Hden_0973
symbol: Hden_0973
gene_biotype: protein_coding
description:
  KEGG: cak:Caul_3954 succinic semialdehyde dehydrogenase; TIGRFAM: succinic semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: Hden_0974
symbol: Hden_0974
gene_biotype: protein_coding
description:
  PFAM: Aldehyde Dehydrogenase; KEGG: cak:Caul_3955 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: Hden_0975
symbol: Hden_0975
gene_biotype: protein_coding
description:
  PFAM: glutamine synthetase catalytic region; KEGG: cak:Caul_3952 glutamine synthetase catalytic region.


ensembl_gene_id: Hden_0977
symbol: Hden_0977
gene_biotype: protein_coding
description:
  PFAM: aminotransferase class-III; KEGG: mlo:mll1207 putative aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: Hden_0978
symbol: Hden_0978
gene_biotype: protein_coding
description:
  Transcriptional regulator, TetR family; PFAM: regulatory protein TetR; Tetracyclin repressor domain protein; KEGG: bac:BamMC406_0585 TetR family transcriptional regulator.


ensembl_gene_id: Hden_0982
symbol: Hden_0982
gene_biotype: protein_coding
description:
  KEGG: bbt:BBta_7804 putative heat shock protein-DnaJ-like protein; PFAM: chaperone DnaJ domain protein; heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein.


ensembl_gene_id: Hden_0986
symbol: Hden_0986
gene_biotype: protein_coding
description:
  Hypothetical protein; KEGG: aga:AgaP_AGAP011790 CLIP-domain serine protease subfamily A (AGAP011790-PB).


ensembl_gene_id: Hden_0989
symbol: idi
gene_biotype: protein_coding
description:
  Isopentenyl-diphosphate delta-isomerase, type 1; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).


ensembl_gene_id: Hden_0992
symbol: Hden_0992
gene_biotype: protein_coding
description:
  PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: nha:Nham_1025 TonB-dependent receptor.


ensembl_gene_id: Hden_0997
symbol: Hden_0997
gene_biotype: protein_coding
description:
  KEGG: hha:Hhal_2401 BadM/Rrf2 family transcriptional regulator; TIGRFAM: transcriptional regulator, Rrf2 family; PFAM: protein of unknown function UPF0074.


ensembl_gene_id: Hden_1002
symbol: Hden_1002
gene_biotype: protein_coding
description:
  Periplasmic glucan biosynthesis protein MdoG; Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).


ensembl_gene_id: Hden_1003
symbol: Hden_1003
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF74; KEGG: cak:Caul_3365 hypothetical protein; Belongs to the UPF0145 family.


ensembl_gene_id: Hden_1004
symbol: secE
gene_biotype: protein_coding
description:
  Preprotein translocase, SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.


ensembl_gene_id: Hden_1005
symbol: nusG
gene_biotype: protein_coding
description:
  NusG antitermination factor; Participates in transcription elongation, termination and antitermination.


ensembl_gene_id: Hden_1006
symbol: rplK
gene_biotype: protein_coding
description:
  Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.


ensembl_gene_id: Hden_1007
symbol: rplA
gene_biotype: protein_coding
description:
  Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.


ensembl_gene_id: Hden_1008
symbol: rplJ
gene_biotype: protein_coding
description:
  Ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.


ensembl_gene_id: Hden_1009
symbol: rplL
gene_biotype: protein_coding
description:
  Ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family.


ensembl_gene_id: Hden_1010
symbol: rpoB
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: Hden_1011
symbol: rpoC
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: Hden_1012
symbol: rpsL
gene_biotype: protein_coding
description:
  Ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.


ensembl_gene_id: Hden_1013
symbol: rpsG
gene_biotype: protein_coding
description:
  Ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.


ensembl_gene_id: Hden_1014
symbol: fusA
gene_biotype: protein_coding
description:
  Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...]


ensembl_gene_id: Hden_1015
symbol: tuf
gene_biotype: protein_coding
description:
  Translation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.


ensembl_gene_id: Hden_1016
symbol: rpsJ
gene_biotype: protein_coding
description:
  Ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.


ensembl_gene_id: Hden_1017
symbol: rplC
gene_biotype: protein_coding
description:
  50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.


ensembl_gene_id: Hden_1019
symbol: rplW
gene_biotype: protein_coding
description:
  Ribosomal protein L25/L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.


ensembl_gene_id: Hden_1020
symbol: rplB
gene_biotype: protein_coding
description:
  Ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.


ensembl_gene_id: Hden_1021
symbol: rpsS
gene_biotype: protein_coding
description:
  Ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.


ensembl_gene_id: Hden_1022
symbol: rplV
gene_biotype: protein_coding
description:
  Ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.


ensembl_gene_id: Hden_1023
symbol: rpsC
gene_biotype: protein_coding
description:
  Ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.


ensembl_gene_id: Hden_1024
symbol: rplP
gene_biotype: protein_coding
description:
  Ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.


ensembl_gene_id: Hden_1025
symbol: rpmC
gene_biotype: protein_coding
description:
  KEGG: bid:Bind_1362 ribosomal protein L29; TIGRFAM: ribosomal protein L29; PFAM: ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family.


ensembl_gene_id: Hden_1026
symbol: rpsQ
gene_biotype: protein_coding
description:
  30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.


ensembl_gene_id: Hden_1027
symbol: rplN
gene_biotype: protein_coding
description:
  Ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.


ensembl_gene_id: Hden_1028
symbol: rplX
gene_biotype: protein_coding
description:
  Ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.


ensembl_gene_id: Hden_1029
symbol: rplE
gene_biotype: protein_coding
description:
  Ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.


ensembl_gene_id: Hden_1030
symbol: rpsN
gene_biotype: protein_coding
description:
  Ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family.


ensembl_gene_id: Hden_1031
symbol: rpsH
gene_biotype: protein_coding
description:
  Ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.


ensembl_gene_id: Hden_1032
symbol: rplF
gene_biotype: protein_coding
description:
  Ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.


ensembl_gene_id: Hden_1033
symbol: rplR
gene_biotype: protein_coding
description:
  Ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.


ensembl_gene_id: Hden_1034
symbol: rpsE
gene_biotype: protein_coding
description:
  Ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.


ensembl_gene_id: Hden_1035
symbol: rpmD
gene_biotype: protein_coding
description:
  KEGG: atu:Atu8065 50S ribosomal protein L30; TIGRFAM: ribosomal protein L30; PFAM: ribosomal protein L30.


ensembl_gene_id: Hden_1036
symbol: rplO
gene_biotype: protein_coding
description:
  Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.


ensembl_gene_id: Hden_1037
symbol: secY
gene_biotype: protein_coding
description:
  Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.


ensembl_gene_id: Hden_1038
symbol: adk
gene_biotype: protein_coding
description:
  Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.


ensembl_gene_id: Hden_1039
symbol: rpsM
gene_biotype: protein_coding
description:
  30S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family.


ensembl_gene_id: Hden_1040
symbol: rpsK
gene_biotype: protein_coding
description:
  30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.


ensembl_gene_id: Hden_1041
symbol: rpoA
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: Hden_1042
symbol: rplQ
gene_biotype: protein_coding
description:
  KEGG: hne:HNE_2826 ribosomal protein L17; TIGRFAM: ribosomal protein L17; PFAM: ribosomal protein L17.


ensembl_gene_id: Hden_1043
symbol: Hden_1043
gene_biotype: protein_coding
description:
  PFAM: NAD-dependent epimerase/dehydratase; KEGG: hne:HNE_3360 NAD-dependent epimerase/dehydratase family protein.


ensembl_gene_id: Hden_1044
symbol: Hden_1044
gene_biotype: protein_coding
description:
  SMART: PDZ/DHR/GLGF domain protein; TIGRFAM: protease Do; KEGG: pla:Plav_2762 protease Do; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; Belongs to the peptidase S1C family.


ensembl_gene_id: Hden_1046
symbol: Hden_1046
gene_biotype: protein_coding
description:
  Sulfate adenylyltransferase, large subunit; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.


ensembl_gene_id: Hden_1047
symbol: cysD
gene_biotype: protein_coding
description:
  KEGG: mlo:mlr7575 sulfate adenylyltransferase subunit 2; TIGRFAM: sulfate adenylyltransferase, small subunit; PFAM: phosphoadenosine phosphosulfate reductase.


ensembl_gene_id: Hden_1051
symbol: Hden_1051
gene_biotype: protein_coding
description:
  Manually curated; PFAM: Cold-shock protein DNA-binding; KEGG: rpc:RPC_2791 cold-shock DNA-binding domain-containing protein; SMART: Cold shock protein.


ensembl_gene_id: Hden_1062
symbol: Hden_1062
gene_biotype: protein_coding
description:
  KEGG: pna:Pnap_2627 ethanolamine ammonia-lyase small subunit; PFAM: Ethanolamine ammonia-lyase light chain; Belongs to the EutC family.


ensembl_gene_id: Hden_1063
symbol: Hden_1063
gene_biotype: protein_coding
description:
  KEGG: pst:PSPTO_0727 ethanolamine ammonia-lyase, heavy subunit; PFAM: Ethanolamine ammonia lyase large subunit.


ensembl_gene_id: Hden_1064
symbol: Hden_1064
gene_biotype: protein_coding
description:
  Ethanolamine transporter; KEGG: pen:PSEEN0633 transport protein; TIGRFAM: ethanolamine transproter; PFAM: amino acid permease-associated region.


ensembl_gene_id: Hden_1065
symbol: Hden_1065
gene_biotype: protein_coding
description:
  KEGG: mei:Msip34_0961 transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain.


ensembl_gene_id: Hden_1066
symbol: Hden_1066
gene_biotype: protein_coding
description:
  Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; PAS fold-4 domain protein; GGDEF domain containing protein; PAS fold-3 domain protein; KEGG: rfr:Rfer_4387 diguanylate cyclase/phosphodiesterase; SMART: EAL domain protein; GGDEF domain containing protein; PAC repeat-containing protein.


ensembl_gene_id: Hden_1068
symbol: ku
gene_biotype: protein_coding
description:
  Ku protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.


ensembl_gene_id: Hden_1069
symbol: Hden_1069
gene_biotype: protein_coding
description:
  Manually curated; TIGRFAM: DNA polymerase LigD, ligase domain protein; KEGG: azc:AZC_1006 ATP-dependent DNA ligase; PFAM: ATP dependent DNA ligase; ATP dependent DNA ligase domain protein.


ensembl_gene_id: Hden_1070
symbol: Hden_1070
gene_biotype: protein_coding
description:
  KEGG: pzu:PHZ_p0051 ATP-dependent DNA ligase; TIGRFAM: DNA polymerase LigD, polymerase domain protein; DNA ligase D, 3'-phosphoesterase domain protein; PFAM: DNA primase small subunit.


ensembl_gene_id: Hden_1073
symbol: Hden_1073
gene_biotype: protein_coding
description:
  PFAM: natural resistance-associated macrophage protein; KEGG: bbt:BBta_7276 putative manganese transport protein.


ensembl_gene_id: Hden_1081
symbol: Hden_1081
gene_biotype: protein_coding
description:
  ErfK/YbiS/YcfS/YnhG family protein; KEGG: azc:AZC_0439 hypothetical protein; manually curated; PFAM: ErfK/YbiS/YcfS/YnhG family protein; Peptidoglycan-binding domain 1 protein.


ensembl_gene_id: Hden_1082
symbol: Hden_1082
gene_biotype: protein_coding
description:
  KEGG: mrd:Mrad2831_2165 cystathionine beta-lyase; TIGRFAM: cystathionine beta-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein.


ensembl_gene_id: Hden_1083
symbol: Hden_1083
gene_biotype: protein_coding
description:
  Extracellular solute-binding protein family 3; KEGG: msl:Msil_1705 cationic amino acid ABC transporter, periplasmic binding protein; PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; Belongs to the bacterial solute-binding protein 3 family.


ensembl_gene_id: Hden_1086
symbol: Hden_1086
gene_biotype: protein_coding
description:
  Von Willebrand factor type A; KEGG: mlo:mlr6511 hypothetical protein; PFAM: von Willebrand factor type A; SMART: von Willebrand factor type A.


ensembl_gene_id: Hden_1088
symbol: nadK
gene_biotype: protein_coding
description:
  ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.


ensembl_gene_id: Hden_1089
symbol: Hden_1089
gene_biotype: protein_coding
description:
  PFAM: CutA1 divalent ion tolerance protein; KEGG: mdi:METDI0519 copper binding protein, copper sensitivity.


ensembl_gene_id: Hden_1092
symbol: Hden_1092
gene_biotype: protein_coding
description:
  Oligopeptidase B; KEGG: pla:Plav_0844 oligopeptidase B; PFAM: peptidase S9A prolyl oligopeptidase domain protein beta-propeller; peptidase S9 prolyl oligopeptidase active site domain protein.


ensembl_gene_id: Hden_1094
symbol: Hden_1094
gene_biotype: protein_coding
description:
  KEGG: hba:Hbal_1230 chromosomal replication initiator DnaA domain; PFAM: Chromosomal replication initiator DnaA domain; SMART: Chromosomal replication initiator DnaA domain.


ensembl_gene_id: Hden_1103
symbol: Hden_1103
gene_biotype: protein_coding
description:
  TIGRFAM: penicillin-binding protein, 1A family; KEGG: bid:Bind_1627 1A family penicillin-binding protein; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase.


ensembl_gene_id: Hden_1104
symbol: Hden_1104
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function UPF0153; KEGG: rhi:NGR_c07710 hypothetical protein; Belongs to the UPF0260 family.


ensembl_gene_id: Hden_1106
symbol: Hden_1106
gene_biotype: protein_coding
description:
  KEGG: pla:Plav_0903 HK97 family phage portal protein; TIGRFAM: phage portal protein, HK97 family; PFAM: portal protein.


ensembl_gene_id: Hden_1110
symbol: Hden_1110
gene_biotype: protein_coding
description:
  KEGG: pla:Plav_0905 HK97 family phage prohead protease; TIGRFAM: phage prohead protease, HK97 family; PFAM: peptidase U35 phage prohead HK97.


ensembl_gene_id: Hden_1111
symbol: Hden_1111
gene_biotype: protein_coding
description:
  KEGG: pla:Plav_0906 HK97 family phage major capsid protein; TIGRFAM: phage major capsid protein, HK97 family; PFAM: major capsid protein HK97.


ensembl_gene_id: Hden_1113
symbol: Hden_1113
gene_biotype: protein_coding
description:
  KEGG: aap:NT05HA_0498 phage head-tail adaptor, putative; TIGRFAM: phage head-tail adaptor; PFAM: putative head-tail adaptor protein.


ensembl_gene_id: Hden_1116
symbol: Hden_1116
gene_biotype: protein_coding
description:
  KEGG: pla:Plav_0911 TP901-1 family phage major tail protein; TIGRFAM: phage major tail protein, TP901-1 family; PFAM: Phage major tail protein, TP901-1, subfamily 1.


ensembl_gene_id: Hden_1121
symbol: Hden_1121
gene_biotype: protein_coding
description:
  PFAM: Phage conserved hypothetical protein, gene transfer agent-like-like; KEGG: pla:Plav_0917 hypothetical protein.


ensembl_gene_id: Hden_1122
symbol: Hden_1122
gene_biotype: protein_coding
description:
  KEGG: nha:Nham_1425 putative phage cell wall peptidase, NlpC/P60; TIGRFAM: phage cell wall peptidase, NlpC/P60 family; PFAM: NLP/P60 protein.


ensembl_gene_id: Hden_1124
symbol: Hden_1124
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF847; Peptidoglycan binding domain; KEGG: mch:Mchl_1579 peptidoglycan-binding domain 1 protein.


ensembl_gene_id: Hden_1126
symbol: Hden_1126
gene_biotype: protein_coding
description:
  Two component transcriptional regulator, winged helix family; KEGG: mes:Meso_0894 two component transcriptional regulator; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver.


ensembl_gene_id: Hden_1127
symbol: Hden_1127
gene_biotype: protein_coding
description:
  Integral membrane sensor signal transduction histidine kinase; KEGG: oca:OCAR_6578 two-component sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein.


ensembl_gene_id: Hden_1129
symbol: Hden_1129
gene_biotype: protein_coding
description:
  KEGG: sme:SMc02361 cytochrome c-type biogenesis transmembrane protein; TIGRFAM: cytochrome c-type biogenesis protein CcmI; SMART: Tetratricopeptide repeat.


ensembl_gene_id: Hden_1130
symbol: ccmE
gene_biotype: protein_coding
description:
  CcmE/CycJ protein; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family.


ensembl_gene_id: Hden_1131
symbol: Hden_1131
gene_biotype: protein_coding
description:
  KEGG: sme:SMc02363 cytochrome c-type biogenesis transmembrane protein; TIGRFAM: cytochrome c-type biogenesis protein CcmF; PFAM: cytochrome c assembly protein.


ensembl_gene_id: Hden_1133
symbol: Hden_1133
gene_biotype: protein_coding
description:
  SMART: PDZ/DHR/GLGF domain protein; TIGRFAM: protease Do; KEGG: bja:blr3130 serine protease DO-like precursor; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; Belongs to the peptidase S1C family.


ensembl_gene_id: Hden_1134
symbol: Hden_1134
gene_biotype: protein_coding
description:
  KEGG: rpd:RPD_2012 winged helix family two component transcriptional regulator; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; transcriptional regulator domain protein.


ensembl_gene_id: Hden_1135
symbol: Hden_1135
gene_biotype: protein_coding
description:
  Integral membrane sensor signal transduction histidine kinase; KEGG: mch:Mchl_0375 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein.


ensembl_gene_id: Hden_1136
symbol: glnE
gene_biotype: protein_coding
description:
  (Glutamate--ammonia-ligase) adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal tra [...]


ensembl_gene_id: Hden_1137
symbol: Hden_1137
gene_biotype: protein_coding
description:
  KEGG: pla:Plav_0951 ECF subfamily RNA polymerase sigma-24 factor; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2.


ensembl_gene_id: Hden_1140
symbol: Hden_1140
gene_biotype: protein_coding
description:
  Histidine kinase A domain protein; KEGG: rec:RHECIAT_CH0001392 probable two-component sensor histidine kinase protein; PFAM: histidine kinase A domain protein; SMART: histidine kinase A domain protein.


ensembl_gene_id: Hden_1141
symbol: Hden_1141
gene_biotype: protein_coding
description:
  KEGG: xau:Xaut_4749 aminopeptidase N; TIGRFAM: aminopeptidase N; PFAM: Peptidase M1 membrane alanine aminopeptidase.


ensembl_gene_id: Hden_1142
symbol: Hden_1142
gene_biotype: protein_coding
description:
  Carboxynorspermidine decarboxylase; Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine; Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.


ensembl_gene_id: Hden_1144
symbol: Hden_1144
gene_biotype: protein_coding
description:
  PFAM: Saccharopine dehydrogenase; KEGG: hne:HNE_0588 saccharopine dehydrogenase (NAD+, L-lysine forming).


ensembl_gene_id: Hden_1146
symbol: Hden_1146
gene_biotype: protein_coding
description:
  PFAM: oxidoreductase molybdopterin binding; Mo-co oxidoreductase dimerisation domain; KEGG: mpt:Mpe_A2086 sulfite oxidase SoxC, putative.


ensembl_gene_id: Hden_1149
symbol: Hden_1149
gene_biotype: protein_coding
description:
  KEGG: azc:AZC_3911 secretion protein; TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: Hden_1150
symbol: Hden_1150
gene_biotype: protein_coding
description:
  KEGG: azc:AZC_3910 hydrophobe/amphiphile efflux-1; TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein.


ensembl_gene_id: Hden_1151
symbol: Hden_1151
gene_biotype: protein_coding
description:
  KEGG: bid:Bind_0441 TPR repeat-containing protein; PFAM: TPR repeat-containing protein; SMART: Tetratricopeptide repeat.


ensembl_gene_id: Hden_1153
symbol: Hden_1153
gene_biotype: protein_coding
description:
  Transcriptional regulator, AraC family; Manually curated; PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: mch:Mchl_0534 transcriptional regulator, AraC family; SMART: Helix-turn-helix, AraC domain.


ensembl_gene_id: Hden_1154
symbol: Hden_1154
gene_biotype: protein_coding
description:
  KEGG: pla:Plav_1409 MarR family transcriptional regulator; PFAM: regulatory protein MarR; SMART: regulatory protein MarR.


ensembl_gene_id: Hden_1160
symbol: Hden_1160
gene_biotype: protein_coding
description:
  KEGG: rsp:RSP_3313 phage integrase family protein; manually curated; PFAM: integrase family protein.


ensembl_gene_id: Hden_1161
symbol: Hden_1161
gene_biotype: protein_coding
description:
  Hypothetical protein; KEGG: cyn:Cyan7425_1808 XRE family plasmid maintenance system antidote protein.


ensembl_gene_id: Hden_1164
symbol: Hden_1164
gene_biotype: protein_coding
description:
  TIGRFAM: restriction alleviation protein, Lar family; KEGG: rsq:Rsph17025_1730 hypothetical protein.


ensembl_gene_id: Hden_1189
symbol: Hden_1189
gene_biotype: protein_coding
description:
  PFAM: D12 class N6 adenine-specific DNA methyltransferase; KEGG: pap:PSPA7_4452 DNA adenine methyltransferase.


ensembl_gene_id: Hden_1205
symbol: Hden_1205
gene_biotype: protein_coding
description:
  Plasmid maintenance system antidote protein, XRE family; SMART: helix-turn-helix domain protein; KEGG: cpi:Cpin_4935 5'-3' DNA helicase.


ensembl_gene_id: Hden_1219
symbol: Hden_1219
gene_biotype: protein_coding
description:
  KEGG: lhk:LHK_01658 phage portal protein, lambda family; TIGRFAM: phage portal protein, lambda family; PFAM: portal protein lambda.


ensembl_gene_id: Hden_1227
symbol: Hden_1227
gene_biotype: protein_coding
description:
  PFAM: Mu tail sheath family protein; KEGG: bbt:BBta_6592 putative Mu-like prophage FluMu tail sheath protein.


ensembl_gene_id: Hden_1230
symbol: Hden_1230
gene_biotype: protein_coding
description:
  KEGG: oan:Oant_0888 TP901 family phage tail tape measure protein; TIGRFAM: phage tail tape measure protein, TP901 family; PFAM: tail tape measure protein TP901 core region.


ensembl_gene_id: Hden_1231
symbol: Hden_1231
gene_biotype: protein_coding
description:
  PFAM: DNA circulation family protein; KEGG: bbt:BBta_6587 putative Mu-like prophage DNA circulation protein.


ensembl_gene_id: Hden_1237
symbol: Hden_1237
gene_biotype: protein_coding
description:
  PFAM: Protein of unknown function DUF2313, Mu protein gp48; KEGG: bbt:BBta_6582 hypothetical protein.


ensembl_gene_id: Hden_1241
symbol: Hden_1241
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF847; Peptidoglycan binding domain; KEGG: xau:Xaut_3175 hypothetical protein.


ensembl_gene_id: Hden_1246
symbol: Hden_1246
gene_biotype: protein_coding
description:
  PFAM: protein-L-isoaspartate(D-aspartate) O-methyltransferase; KEGG: pla:Plav_3003 protein-L-isoaspartate(D-aspartate) O-methyltransferase.


ensembl_gene_id: Hden_1247
symbol: Hden_1247
gene_biotype: protein_coding
description:
  KEGG: mpo:Mpop_5239 type I secretion outer membrane protein, TolC family; TIGRFAM: type I secretion outer membrane protein, TolC family; PFAM: outer membrane efflux protein.


ensembl_gene_id: Hden_1250
symbol: valS
gene_biotype: protein_coding
description:
  valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.


ensembl_gene_id: Hden_1253
symbol: ilvD-2
gene_biotype: protein_coding
description:
  TIGRFAM: dihydroxy-acid dehydratase; KEGG: pla:Plav_3010 dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family.


ensembl_gene_id: Hden_1254
symbol: Hden_1254
gene_biotype: protein_coding
description:
  PFAM: Sel1 domain protein repeat-containing protein; KEGG: mno:Mnod_5367 Sel1 domain protein repeat-containing protein.


ensembl_gene_id: Hden_1255
symbol: Hden_1255
gene_biotype: protein_coding
description:
  KEGG: rsp:RSP_2657 exodeoxyribonuclease III; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase.


ensembl_gene_id: Hden_1256
symbol: Hden_1256
gene_biotype: protein_coding
description:
  KEGG: mpo:Mpop_3583 iron-sulfur cluster assembly accessory protein; TIGRFAM: iron-sulfur cluster assembly accessory protein; PFAM: HesB/YadR/YfhF-family protein; Belongs to the HesB/IscA family.


ensembl_gene_id: Hden_1257
symbol: Hden_1257
gene_biotype: protein_coding
description:
  TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; KEGG: mes:Meso_1814 deoxyguanosinetriphosphate triphosphohydrolase-like protein; SMART: metal-dependent phosphohydrolase HD region; Belongs to the dGTPase family. Type 2 subfamily.


ensembl_gene_id: Hden_1260
symbol: Hden_1260
gene_biotype: protein_coding
description:
  Chromosome segregation and condensation protein ScpA; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.


ensembl_gene_id: Hden_1261
symbol: Hden_1261
gene_biotype: protein_coding
description:
  Chromosome segregation and condensation protein, ScpB; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.


ensembl_gene_id: Hden_1262
symbol: tatA
gene_biotype: protein_coding
description:
  Twin-arginine translocation protein, TatA/E family subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.


ensembl_gene_id: Hden_1263
symbol: tatB
gene_biotype: protein_coding
description:
  Twin-arginine translocation protein, TatB subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.


ensembl_gene_id: Hden_1264
symbol: tatC
gene_biotype: protein_coding
description:
  Sec-independent protein translocase, TatC subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.


ensembl_gene_id: Hden_1265
symbol: serS
gene_biotype: protein_coding
description:
  seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).


ensembl_gene_id: Hden_1267
symbol: surE
gene_biotype: protein_coding
description:
  Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.


ensembl_gene_id: Hden_1269
symbol: Hden_1269
gene_biotype: protein_coding
description:
  Peptidase M23; KEGG: rpb:RPB_2736 peptidase M23B; PFAM: Peptidase M23; Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding LysM.


ensembl_gene_id: Hden_1271
symbol: yajC
gene_biotype: protein_coding
description:
  Preprotein translocase, YajC subunit; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.


ensembl_gene_id: Hden_1272
symbol: secD
gene_biotype: protein_coding
description:
  Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.


ensembl_gene_id: Hden_1273
symbol: secF
gene_biotype: protein_coding
description:
  Protein-export membrane protein SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.


ensembl_gene_id: Hden_1277
symbol: trmFO
gene_biotype: protein_coding
description:
  Gid protein; Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs; Belongs to the MnmG family. TrmFO subfamily.


ensembl_gene_id: Hden_1279
symbol: mntH
gene_biotype: protein_coding
description:
  Mn2+/Fe2+ transporter, NRAMP family; H(+)-stimulated, divalent metal cation uptake system. Belongs to the NRAMP family.


ensembl_gene_id: Hden_1280
symbol: Hden_1280
gene_biotype: protein_coding
description:
  PFAM: Protein of unknown function DUF2157, membrane; KEGG: pla:Plav_2660 membrane protein-like protein.


ensembl_gene_id: Hden_1286
symbol: hppA
gene_biotype: protein_coding
description:
  V-type H(+)-translocating pyrophosphatase; Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.


ensembl_gene_id: Hden_1291
symbol: plsX
gene_biotype: protein_coding
description:
  Fatty acid/phospholipid synthesis protein PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.


ensembl_gene_id: Hden_1292
symbol: fabH
gene_biotype: protein_coding
description:
  3-oxoacyl-(acyl-carrier-protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.


ensembl_gene_id: Hden_1293
symbol: ihfA
gene_biotype: protein_coding
description:
  Integration host factor, alpha subunit; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.


ensembl_gene_id: Hden_1294
symbol: Hden_1294
gene_biotype: protein_coding
description:
  Transcriptional regulator, MerR family; KEGG: oca:OCAR_5878 regulatory protein, MerR; PFAM: regulatory protein MerR; SMART: regulatory protein MerR.


ensembl_gene_id: Hden_1295
symbol: Hden_1295
gene_biotype: protein_coding
description:
  Phosphopantetheinyl transferase-like protein; KEGG: mrd:Mrad2831_0013 4'-phosphopantetheinyl transferase.


ensembl_gene_id: Hden_1299
symbol: Hden_1299
gene_biotype: protein_coding
description:
  KEGG: cli:Clim_0620 glycine cleavage system H protein; TIGRFAM: glycine cleavage system H protein; PFAM: glycine cleavage H-protein.


ensembl_gene_id: Hden_1300
symbol: Hden_1300
gene_biotype: protein_coding
description:
  KEGG: cdf:CD0723 putative carbon monoxide dehydrogenase/acetyl-CoA synthase complex, dihydrolipoyl dehydrogenase subunit; TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region.


ensembl_gene_id: Hden_1302
symbol: Hden_1302
gene_biotype: protein_coding
description:
  KEGG: vap:Vapar_2160 two component transcriptional regulator, LuxR family; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR.


ensembl_gene_id: Hden_1303
symbol: Hden_1303
gene_biotype: protein_coding
description:
  PAS/PAC sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; KEGG: app:CAP2UW1_2103 multi-sensor signal transduction histidine kinase; SMART: ATP-binding region ATPase domain protein; PAC repeat-containing protein; PAS domain containing protein; histidine kinase A domain protein.


ensembl_gene_id: Hden_1305
symbol: Hden_1305
gene_biotype: protein_coding
description:
  TIGRFAM: PQQ-dependent dehydrogenase, methanol/ethanol family; PFAM: PQQ-dependent enzyme-like; Pyrrolo-quinoline quinone; KEGG: xau:Xaut_1781 pyrrolo-quinoline quinone; SMART: Pyrrolo-quinoline quinone beta-propeller repeat.


ensembl_gene_id: Hden_1307
symbol: Hden_1307
gene_biotype: protein_coding
description:
  KEGG: bbt:BBta_5941 two component LuxR family transcriptional regulator; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR.


ensembl_gene_id: Hden_1308
symbol: Hden_1308
gene_biotype: protein_coding
description:
  SMART: Calcium-binding EF-hand-containing protein; KEGG: mch:Mchl_2189 putative signal transduction protein with EFhand domain.


ensembl_gene_id: Hden_1312
symbol: Hden_1312
gene_biotype: protein_coding
description:
  TIGRFAM: 40-residue YVTN family beta-propeller repeat protein; KEGG: msl:Msil_0482 40-residue YVTN family beta-propeller repeat protein.


ensembl_gene_id: Hden_1316
symbol: Hden_1316
gene_biotype: protein_coding
description:
  KEGG: rpe:RPE_3132 von Willebrand factor, type A; PFAM: von Willebrand factor type A; SMART: von Willebrand factor type A.


ensembl_gene_id: Hden_1319
symbol: Hden_1319
gene_biotype: protein_coding
description:
  KEGG: rpc:RPC_1911 ATPase; PFAM: ATPase associated with various cellular activities AAA_3; SMART: AAA ATPase.


ensembl_gene_id: Hden_1320
symbol: Hden_1320
gene_biotype: protein_coding
description:
  Methanol dehydrogenase beta subunit; Catalyzes the oxidation of primary alcohols including methanol.


ensembl_gene_id: Hden_1322
symbol: Hden_1322
gene_biotype: protein_coding
description:
  KEGG: rpc:RPC_1908 extracellular solute-binding protein; PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3.


ensembl_gene_id: Hden_1323
symbol: Hden_1323
gene_biotype: protein_coding
description:
  TIGRFAM: PQQ-dependent dehydrogenase, methanol/ethanol family; PFAM: PQQ-dependent enzyme-like; Pyrrolo-quinoline quinone; KEGG: rpc:RPC_1907 pyrrolo-quinoline quinone; SMART: Pyrrolo-quinoline quinone beta-propeller repeat.


ensembl_gene_id: Hden_1325
symbol: Hden_1325
gene_biotype: protein_coding
description:
  Integral membrane sensor signal transduction histidine kinase; Manually curated; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase dimerisation and phosphoacceptor region; KEGG: rpe:RPE_3141 putative signal transduction histidine kinase; SMART: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein.


ensembl_gene_id: Hden_1326
symbol: Hden_1326
gene_biotype: protein_coding
description:
  KEGG: rpc:RPC_1904 two component LuxR family transcriptional regulator; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR.


ensembl_gene_id: Hden_1330
symbol: Hden_1330
gene_biotype: protein_coding
description:
  SMART: Helix-turn-helix, AraC domain; KEGG: rce:RC1_3211 transcriptional regulator, AraC family protein.


ensembl_gene_id: Hden_1331
symbol: Hden_1331
gene_biotype: protein_coding
description:
  KEGG: oca:OCAR_6490 ferrichrome-iron receptor; TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor plug; TonB-dependent receptor.


ensembl_gene_id: Hden_1332
symbol: Hden_1332
gene_biotype: protein_coding
description:
  PFAM: PepSY-associated TM helix domain protein; KEGG: oca:OCAR_6489 PepSY-associated TM helix domain protein.


ensembl_gene_id: Hden_1335
symbol: Hden_1335
gene_biotype: protein_coding
description:
  PFAM: Lycopene beta and epsilon cyclase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: bra:BRADO4820 putative oxidoreductase; NAD(FAD)-dependent dehydrogenases.


ensembl_gene_id: Hden_1339
symbol: Hden_1339
gene_biotype: protein_coding
description:
  KEGG: hypothetical protein; PFAM: Transcription factor jumonji; SMART: transcription factor jumonji jmjC domain protein.


ensembl_gene_id: Hden_1340
symbol: Hden_1340
gene_biotype: protein_coding
description:
  KEGG: npu:Npun_CR072 amino acid adenylation domain-containing protein; TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; phosphopantetheine-binding.


ensembl_gene_id: Hden_1341
symbol: Hden_1341
gene_biotype: protein_coding
description:
  PFAM: Beta-ketoacyl synthase; phosphopantetheine-binding; Acyl transferase; aminotransferase class-III; KEGG: npu:Npun_R6590 beta-ketoacyl synthase.


ensembl_gene_id: Hden_1342
symbol: Hden_1342
gene_biotype: protein_coding
description:
  KEGG: npu:Npun_R3023 amino acid adenylation domain-containing protein; TIGRFAM: amino acid adenylation domain protein; non-ribosomal peptide synthase; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; phosphopantetheine-binding.


ensembl_gene_id: Hden_1344
symbol: Hden_1344
gene_biotype: protein_coding
description:
  PFAM: 4'-phosphopantetheinyl transferase; KEGG: npu:Npun_R2089 4'-phosphopantetheinyl transferase; Belongs to the P-Pant transferase superfamily.


ensembl_gene_id: Hden_1345
symbol: Hden_1345
gene_biotype: protein_coding
description:
  PFAM: polysaccharide biosynthesis protein; KEGG: bra:BRADO4827 putative polysaccharide transport protein.


ensembl_gene_id: Hden_1347
symbol: Hden_1347
gene_biotype: protein_coding
description:
  KEGG: swi:Swit_0848 WecB/TagA/CpsF family glycosyl transferase; TIGRFAM: glycosyl transferase, WecB/TagA/CpsF family; PFAM: glycosyl transferase WecB/TagA/CpsF; Belongs to the glycosyltransferase 26 family.


ensembl_gene_id: Hden_1350
symbol: Hden_1350
gene_biotype: protein_coding
description:
  PFAM: O-antigen polymerase; KEGG: bra:BRADO4815 putative exopolysaccharide production protein (ExoQ-like); putative membrane protein.


ensembl_gene_id: Hden_1354
symbol: Hden_1354
gene_biotype: protein_coding
description:
  PFAM: lipopolysaccharide biosynthesis protein; KEGG: bid:Bind_2762 lipopolysaccharide biosynthesis protein.


ensembl_gene_id: Hden_1355
symbol: Hden_1355
gene_biotype: protein_coding
description:
  KEGG: ret:RHE_CH03235 exopolysaccharide export protein; manually curated; PFAM: polysaccharide export protein.


ensembl_gene_id: Hden_1356
symbol: Hden_1356
gene_biotype: protein_coding
description:
  TIGRFAM: asparagine synthase (glutamine-hydrolyzing); KEGG: bra:BRADO4822 putative asparagine synthetase; PFAM: asparagine synthase; glutamine amidotransferase class-II.


ensembl_gene_id: Hden_1357
symbol: Hden_1357
gene_biotype: protein_coding
description:
  KEGG: pla:Plav_1925 sugar transferase; TIGRFAM: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; PFAM: sugar transferase.


ensembl_gene_id: Hden_1361
symbol: Hden_1361
gene_biotype: protein_coding
description:
  KEGG: mes:Meso_1527 alpha,alpha-trehalose-phosphate synthase (UDP-forming); PFAM: glycosyl transferase family 20.


ensembl_gene_id: Hden_1364
symbol: Hden_1364
gene_biotype: protein_coding
description:
  TIGRFAM: PAS sensor protein; PFAM: HWE histidine kinase; response regulator receiver; PAS fold-3 domain protein; KEGG: bja:bll2598 two-component response regulator; SMART: response regulator receiver.


ensembl_gene_id: Hden_1365
symbol: Hden_1365
gene_biotype: protein_coding
description:
  GAF sensor hybrid histidine kinase; KEGG: bja:bll2599 two-component hybrid sensor and regulator; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; GAF domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; response regulator receiver.


ensembl_gene_id: Hden_1366
symbol: Hden_1366
gene_biotype: protein_coding
description:
  KEGG: bid:Bind_3241 ECF subfamily RNA polymerase sigma-24 factor; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein.


ensembl_gene_id: Hden_1368
symbol: Hden_1368
gene_biotype: protein_coding
description:
  KEGG: swi:Swit_3925 two-component response regulator; PFAM: response regulator receiver; SMART: response regulator receiver.


ensembl_gene_id: Hden_1373
symbol: Hden_1373
gene_biotype: protein_coding
description:
  PFAM: superoxide dismutase copper/zinc binding; KEGG: dds:Ddes_0538 superoxide dismutase copper/zinc binding.


ensembl_gene_id: Hden_1376
symbol: Hden_1376
gene_biotype: protein_coding
description:
  KEGG: msl:Msil_3144 two component transcriptional regulator, LuxR family; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR.


ensembl_gene_id: Hden_1377
symbol: Hden_1377
gene_biotype: protein_coding
description:
  KEGG: msl:Msil_3151 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase dimerisation and phosphoacceptor region; SMART: histidine kinase HAMP region domain protein; ATP-binding region ATPase domain protein.


ensembl_gene_id: Hden_1379
symbol: Hden_1379
gene_biotype: protein_coding
description:
  KEGG: mno:Mnod_5211 undecaprenyl-phosphate glucose phosphotransferase; TIGRFAM: Undecaprenyl-phosphate glucose phosphotransferase; exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; PFAM: sugar transferase.


ensembl_gene_id: Hden_1381
symbol: Hden_1381
gene_biotype: protein_coding
description:
  PFAM: polysaccharide export protein; Soluble ligand binding domain; KEGG: nwi:Nwi_1414 polysaccharide export protein.


ensembl_gene_id: Hden_1385
symbol: ctaA
gene_biotype: protein_coding
description:
  Cytochrome oxidase assembly; Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group; Belongs to the COX15/CtaA family. Type 2 subfamily.


ensembl_gene_id: Hden_1386
symbol: argC
gene_biotype: protein_coding
description:
  N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 2 subfamily.


ensembl_gene_id: Hden_1388
symbol: rpsI
gene_biotype: protein_coding
description:
  PFAM: ribosomal protein S9; KEGG: oan:Oant_2496 30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.


ensembl_gene_id: Hden_1389
symbol: rplM
gene_biotype: protein_coding
description:
  Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.


ensembl_gene_id: Hden_1390
symbol: Hden_1390
gene_biotype: protein_coding
description:
  PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: xau:Xaut_3191 putative 6-pyruvoyl tetrahydropterin synthase.


ensembl_gene_id: Hden_1393
symbol: Hden_1393
gene_biotype: protein_coding
description:
  PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: dar:Daro_3011 glyoxalase/bleomycin resistance protein/dioxygenase.


ensembl_gene_id: Hden_1394
symbol: Hden_1394
gene_biotype: protein_coding
description:
  KEGG: ddc:Dd586_2991 CoA-binding domain protein; PFAM: CoA-binding domain protein; SMART: CoA-binding domain protein.


ensembl_gene_id: Hden_1395
symbol: Hden_1395
gene_biotype: protein_coding
description:
  GTP cyclohydrolase II; KEGG: ace:Acel_1272 bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein; PFAM: GTP cyclohydrolase II.


ensembl_gene_id: Hden_1397
symbol: Hden_1397
gene_biotype: protein_coding
description:
  KEGG: bra:BRADO4696 putative alpha-isopropylmalate/homocitrate synthase family transferase; TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein; PFAM: LeuA allosteric (dimerisation) domain; pyruvate carboxyltransferase; Belongs to the alpha-IPM synthase/homocitrate synthase family.


ensembl_gene_id: Hden_1401
symbol: Hden_1401
gene_biotype: protein_coding
description:
  PFAM: Flavocytochrome c sulphide dehydrogenase flavin-binding; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: xau:Xaut_1514 flavocytochrome c sulphide dehydrogenase flavin-binding.


ensembl_gene_id: Hden_1402
symbol: Hden_1402
gene_biotype: protein_coding
description:
  PFAM: Protein of unknown function DUF1974; acyl-CoA dehydrogenase domain protein; KEGG: slt:Slit_1861 protein of unknown function DUF1974.


ensembl_gene_id: Hden_1403
symbol: Hden_1403
gene_biotype: protein_coding
description:
  PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; 3-hydroxyacyl-CoA dehydrogenase domain protein; Enoyl-CoA hydratase/isomerase; KEGG: nha:Nham_1087 3-hydroxyacyl-CoA dehydrogenase, NAD-binding; Belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: Hden_1404
symbol: Hden_1404
gene_biotype: protein_coding
description:
  acetyl-CoA acetyltransferase; KEGG: pfs:PFLU0655 putative thiolase; TIGRFAM: acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.


ensembl_gene_id: Hden_1405
symbol: Hden_1405
gene_biotype: protein_coding
description:
  PFAM: Cyclopropane-fatty-acyl-phospholipid synthase; KEGG: mlo:mll4091 fatty acid synthase, cyclopropane-fatty-acyl-phospholipid synthase.


ensembl_gene_id: Hden_1406
symbol: Hden_1406
gene_biotype: protein_coding
description:
  TIGRFAM: glucan exporter ATP-binding protein; PFAM: ABC transporter related; ABC transporter transmembrane region; KEGG: atc:AGR_C_4944 beta-(1-->2)glucan export ATP-binding protein ChvA (attachment protein); SMART: AAA ATPase.


ensembl_gene_id: Hden_1415
symbol: Hden_1415
gene_biotype: protein_coding
description:
  TIGRFAM: HAD-superfamily subfamily IIA hydrolase like protein; HAD-superfamily hydrolase, subfamily IIA; KEGG: azc:AZC_0099 HAD-superfamily hydrolase.


ensembl_gene_id: Hden_1419
symbol: Hden_1419
gene_biotype: protein_coding
description:
  PFAM: Aldehyde Dehydrogenase; KEGG: bid:Bind_0016 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: Hden_1420
symbol: Hden_1420
gene_biotype: protein_coding
description:
  KEGG: pna:Pnap_3729 response regulator receiver protein; PFAM: response regulator receiver; SMART: response regulator receiver.


ensembl_gene_id: Hden_1421
symbol: Hden_1421
gene_biotype: protein_coding
description:
  KEGG: mxa:MXAN_2606 sensor histidine kinase/response regulator; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein.


ensembl_gene_id: Hden_1423
symbol: Hden_1423
gene_biotype: protein_coding
description:
  KEGG: rme:Rmet_2949 response regulator receiver domain-containing protein; PFAM: response regulator receiver; SMART: response regulator receiver.


ensembl_gene_id: Hden_1425
symbol: Hden_1425
gene_biotype: protein_coding
description:
  Extracellular solute-binding protein family 1; Required for the activity of the bacterial periplasmic transport system of putrescine; Belongs to the bacterial solute-binding protein PotD/PotF family.


ensembl_gene_id: Hden_1426
symbol: potA
gene_biotype: protein_coding
description:
  Spermidine/putrescine ABC transporter ATPase subunit; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.


ensembl_gene_id: Hden_1427
symbol: Hden_1427
gene_biotype: protein_coding
description:
  PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: mes:Meso_0165 binding-protein-dependent transport systems inner membrane component.


ensembl_gene_id: Hden_1428
symbol: Hden_1428
gene_biotype: protein_coding
description:
  PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: mes:Meso_0166 binding-protein-dependent transport systems inner membrane component.


ensembl_gene_id: Hden_1431
symbol: Hden_1431
gene_biotype: protein_coding
description:
  RNA polymerase, sigma-24 subunit, ECF subfamily; Manually curated; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; KEGG: rpt:Rpal_2016 RNA polymerase sigma factor; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: Hden_1433
symbol: Hden_1433
gene_biotype: protein_coding
description:
  PFAM: molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; molybdopterin oxidoreductase; KEGG: msl:Msil_2953 formate dehydrogenase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: Hden_1435
symbol: Hden_1435
gene_biotype: protein_coding
description:
  SMART: Elongator protein 3/MiaB/NifB; TIGRFAM: lysine 2,3-aminomutase YodO family protein; KEGG: xau:Xaut_3908 lysine 2,3-aminomutase YodO family protein; PFAM: Radical SAM domain protein.


ensembl_gene_id: Hden_1436
symbol: Hden_1436
gene_biotype: protein_coding
description:
  PFAM: glutathione-dependent formaldehyde-activating GFA; KEGG: mes:Meso_0968 glutathione-dependent formaldehyde-activating, GFA.


ensembl_gene_id: Hden_1437
symbol: Hden_1437
gene_biotype: protein_coding
description:
  Lysine--tRNA ligase; Manually curated; KEGG: cak:Caul_0762 lysine--tRNA ligase; PFAM: tRNA synthetase class II (D K and N).


ensembl_gene_id: Hden_1438
symbol: efp
gene_biotype: protein_coding
description:
  Translation elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.


ensembl_gene_id: Hden_1439
symbol: Hden_1439
gene_biotype: protein_coding
description:
  Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.


ensembl_gene_id: Hden_1440
symbol: moaC
gene_biotype: protein_coding
description:
  Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.


ensembl_gene_id: Hden_1441
symbol: trpC
gene_biotype: protein_coding
description:
  KEGG: xau:Xaut_4375 indole-3-glycerol-phosphate synthase; PFAM: Indole-3-glycerol phosphate synthase; Belongs to the TrpC family.


ensembl_gene_id: Hden_1442
symbol: trpD
gene_biotype: protein_coding
description:
  Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).


ensembl_gene_id: Hden_1443
symbol: Hden_1443
gene_biotype: protein_coding
description:
  KEGG: xau:Xaut_4377 glutamine amidotransferase of anthranilate synthase; TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I.


ensembl_gene_id: Hden_1444
symbol: Hden_1444
gene_biotype: protein_coding
description:
  Putative phosphohistidine phosphatase, SixA; KEGG: sme:SMc03822 hypothetical protein; PFAM: Phosphoglycerate mutase; SMART: Phosphoglycerate mutase.


ensembl_gene_id: Hden_1446
symbol: trpE
gene_biotype: protein_coding
description:
  Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...]


ensembl_gene_id: Hden_1448
symbol: tpiA
gene_biotype: protein_coding
description:
  Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.


ensembl_gene_id: Hden_1451
symbol: Hden_1451
gene_biotype: protein_coding
description:
  Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.


ensembl_gene_id: Hden_1453
symbol: pyrG
gene_biotype: protein_coding
description:
  CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.


ensembl_gene_id: Hden_1455
symbol: kdsA
gene_biotype: protein_coding
description:
  KEGG: rpt:Rpal_3223 2-dehydro-3-deoxyphosphooctonate aldolase; TIGRFAM: 2-dehydro-3-deoxyphosphooctonate aldolase; PFAM: DAHP synthetase I/KDSA.


ensembl_gene_id: Hden_1459
symbol: Hden_1459
gene_biotype: protein_coding
description:
  KEGG: bbt:BBta_5947 putative ABC transporter ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase.


ensembl_gene_id: Hden_1460
symbol: Hden_1460
gene_biotype: protein_coding
description:
  TIGRFAM: 40-residue YVTN family beta-propeller repeat protein; PFAM: cytochrome d1 heme region; Aldehyde Dehydrogenase; KEGG: mno:Mnod_5316 40-residue YVTN family beta-propeller repeat protein; SMART: WD-40 repeat protein.


ensembl_gene_id: Hden_1463
symbol: Hden_1463
gene_biotype: protein_coding
description:
  PFAM: NMT1/THI5 like domain protein; KEGG: azl:AZL_a05750 ABC transporter substrate-binding protein.


ensembl_gene_id: Hden_1464
symbol: Hden_1464
gene_biotype: protein_coding
description:
  PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: psa:PST_2932 sulfonate ABC transporter, permease protein, putative.


ensembl_gene_id: Hden_1465
symbol: Hden_1465
gene_biotype: protein_coding
description:
  KEGG: azl:AZL_a05770 ABC transporter ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase.


ensembl_gene_id: Hden_1467
symbol: Hden_1467
gene_biotype: protein_coding
description:
  KEGG: mag:amb2297 dihydroneopterin aldolase; PFAM: dihydroneopterin aldolase; SMART: dihydroneopterin aldolase.


ensembl_gene_id: Hden_1468
symbol: Hden_1468
gene_biotype: protein_coding
description:
  PFAM: aspartate/glutamate/uridylate kinase; KEGG: msl:Msil_2395 aspartate/glutamate/uridylate kinase.


ensembl_gene_id: Hden_1472
symbol: Hden_1472
gene_biotype: protein_coding
description:
  TIGRFAM: H4MPT-linked C1 transfer pathway protein; KEGG: mrd:Mrad2831_0965 H4MPT-linked C1 transfer pathway protein.


ensembl_gene_id: Hden_1473
symbol: Hden_1473
gene_biotype: protein_coding
description:
  PFAM: histidine biosynthesis protein; KEGG: gbe:GbCGDNIH1_0769 phosphoribosylformimino-5-aminoimidazole carboxamide isomerase family protein; Belongs to the HisA/HisF family.


ensembl_gene_id: Hden_1474
symbol: Hden_1474
gene_biotype: protein_coding
description:
  KEGG: xau:Xaut_0032 formaldehyde-activating protein; TIGRFAM: formaldehyde-activating enzyme; PFAM: Formaldehyde-activating enzyme (Fae).


ensembl_gene_id: Hden_1475
symbol: Hden_1475
gene_biotype: protein_coding
description:
  PFAM: triphosphoribosyl-dephospho-CoA protein; KEGG: met:M446_5782 triphosphoribosyl-dephospho-CoA protein.


ensembl_gene_id: Hden_1476
symbol: Hden_1476
gene_biotype: protein_coding
description:
  KEGG: mno:Mnod_6005 alpha-L-glutamate ligase, RimK family; TIGRFAM: alpha-L-glutamate ligase, RimK family; PFAM: RimK domain protein ATP-grasp; Belongs to the RimK family.


ensembl_gene_id: Hden_1477
symbol: mch
gene_biotype: protein_coding
description:
  Methenyltetrahydromethanopterin cyclohydrolase; Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-formyl- H(4)MPT; Belongs to the MCH family.


ensembl_gene_id: Hden_1479
symbol: Hden_1479
gene_biotype: protein_coding
description:
  PFAM: Methylene-tetrahydromethanopterin dehydrogenase; KEGG: msl:Msil_2385 methylenetetrahydrofolate dehydrogenase (NADP(+)).


ensembl_gene_id: Hden_1480
symbol: Hden_1480
gene_biotype: protein_coding
description:
  KEGG: msl:Msil_2384 beta-ribofuranosylaminobenzene 5'-phosphate synthase family; TIGRFAM: beta-ribofuranosylaminobenzene 5'-phosphate synthase family; PFAM: GHMP kinase; GHMP kinase domain protein.


ensembl_gene_id: Hden_1481
symbol: Hden_1481
gene_biotype: protein_coding
description:
  PFAM: transcriptional coactivator/pterin dehydratase; KEGG: mrd:Mrad2831_2778 transcriptional coactivator/pterin dehydratase.


ensembl_gene_id: Hden_1482
symbol: Hden_1482
gene_biotype: protein_coding
description:
  TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; KEGG: mno:Mnod_5981 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK.


ensembl_gene_id: Hden_1486
symbol: pqqC
gene_biotype: protein_coding
description:
  Coenzyme PQQ biosynthesis protein C; Ring cyclization and eight-electron oxidation of 3a-(2-amino- 2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9- dicarboxylic-acid to PQQ.


ensembl_gene_id: Hden_1487
symbol: pqqB
gene_biotype: protein_coding
description:
  Coenzyme PQQ biosynthesis protein B; May be involved in the transport of PQQ or its precursor to the periplasm; Belongs to the PqqB family.


ensembl_gene_id: Hden_1488
symbol: Hden_1488
gene_biotype: protein_coding
description:
  KEGG: mex:Mext_1820 coenzyme PQQ biosynthesis protein A; TIGRFAM: coenzyme PQQ biosynthesis protein A; PFAM: coenzyme PQQ biosynthesis protein A.


ensembl_gene_id: Hden_1490
symbol: Hden_1490
gene_biotype: protein_coding
description:
  Flavodoxin/nitric oxide synthase; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.


ensembl_gene_id: Hden_1491
symbol: cysI
gene_biotype: protein_coding
description:
  Nitrite and sulphite reductase 4Fe-4S region; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.


ensembl_gene_id: Hden_1493
symbol: Hden_1493
gene_biotype: protein_coding
description:
  AAA ATPase central domain protein; KEGG: rpe:RPE_3556 recombination factor protein RarA; PFAM: AAA ATPase central domain protein; SMART: AAA ATPase.


ensembl_gene_id: Hden_1495
symbol: Hden_1495
gene_biotype: protein_coding
description:
  Pseudouridine synthase, RluA family; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.


ensembl_gene_id: Hden_1497
symbol: Hden_1497
gene_biotype: protein_coding
description:
  KEGG: gph1; phosphoglycolate phosphatase-1; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase.


ensembl_gene_id: Hden_1499
symbol: Hden_1499
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF21; CBS domain containing protein; transporter-associated region; KEGG: met:M446_5725 hypothetical protein.


ensembl_gene_id: Hden_1505
symbol: Hden_1505
gene_biotype: protein_coding
description:
  PFAM: 6-phosphogluconate dehydrogenase NAD-binding; KEGG: rpc:RPC_1857 6-phosphogluconate dehydrogenase, NAD-binding.


ensembl_gene_id: Hden_1508
symbol: Hden_1508
gene_biotype: protein_coding
description:
  TIGRFAM: copper-translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; heavy metal translocating P-type ATPase; PFAM: E1-E2 ATPase-associated domain protein; YHS domain protein; Haloacid dehalogenase domain protein hydrolase; KEGG: rpt:Rpal_1856 heavy metal translocating P-type ATPase; SMART: TRASH domain protein.


ensembl_gene_id: Hden_1514
symbol: parC
gene_biotype: protein_coding
description:
  DNA topoisomerase IV, A subunit; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.


ensembl_gene_id: Hden_1516
symbol: bpt
gene_biotype: protein_coding
description:
  Arginine-tRNA-protein transferase domain protein; Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate. Belongs to the R-transferase family. Bpt subfamily.


ensembl_gene_id: Hden_1519
symbol: Hden_1519
gene_biotype: protein_coding
description:
  TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; KEGG: mno:Mnod_4793 O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein.


ensembl_gene_id: Hden_1521
symbol: Hden_1521
gene_biotype: protein_coding
description:
  KEGG: mno:Mnod_6027 poly(R)-hydroxyalkanoic acid synthase, class I; TIGRFAM: poly(R)-hydroxyalkanoic acid synthase, class I; PFAM: Poly-beta-hydroxybutyrate polymerase domain protein; alpha/beta hydrolase fold.


ensembl_gene_id: Hden_1523
symbol: Hden_1523
gene_biotype: protein_coding
description:
  PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; amino acid-binding ACT domain protein; KEGG: oan:Oant_1917 homoserine dehydrogenase.


ensembl_gene_id: Hden_1524
symbol: Hden_1524
gene_biotype: protein_coding
description:
  TIGRFAM: fructose-1,6-bisphosphatase, class II; KEGG: bmr:BMI_I1284 fructose 1,6-bisphosphatase II; PFAM: GlpX family protein.


ensembl_gene_id: Hden_1525
symbol: Hden_1525
gene_biotype: protein_coding
description:
  KEGG: ara:Arad_2163 single-stranded-DNA-specific exonuclease protein; TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1.


ensembl_gene_id: Hden_1605
symbol: Hden_1605
gene_biotype: protein_coding
description:
  PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; cytochrome c biogenesis protein transmembrane region; KEGG: bxe:Bxe_B0816 putative transmembrane protein.


ensembl_gene_id: Hden_1608
symbol: Hden_1608
gene_biotype: protein_coding
description:
  KEGG: mea:Mex_1p1755 formyltransferase/hydrolase complex Fhc subunit C; TIGRFAM: formylmethanofuran dehydrogenase subunit C; PFAM: glutamate synthase alpha subunit domain protein.


ensembl_gene_id: Hden_1609
symbol: ffsA
gene_biotype: protein_coding
description:
  Formylmethanofuran/tetrahydromethanopterin N-formyltransferase; Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT); Belongs to the FTR family.


ensembl_gene_id: Hden_1610
symbol: Hden_1610
gene_biotype: protein_coding
description:
  KEGG: mca:MCA2859 formylmethanofurane dehydrogenase, A subunit, putative; TIGRFAM: formylmethanofuran dehydrogenase subunit A; PFAM: Amidohydrolase 3.


ensembl_gene_id: Hden_1612
symbol: Hden_1612
gene_biotype: protein_coding
description:
  PFAM: Polyketide cyclase/dehydrase; KEGG: mpo:Mpop_1790 conserved hypothetical protein; putative signal peptide.


ensembl_gene_id: Hden_1613
symbol: Hden_1613
gene_biotype: protein_coding
description:
  KEGG: bja:bll4706 hypothetical protein; TIGRFAM: 40-residue YVTN family beta-propeller repeat protein; PFAM: NHL repeat containing protein.


ensembl_gene_id: Hden_1619
symbol: Hden_1619
gene_biotype: protein_coding
description:
  KEGG: rpe:RPE_0853 extracellular solute-binding protein; PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3.


ensembl_gene_id: Hden_1621
symbol: Hden_1621
gene_biotype: protein_coding
description:
  PFAM: sodium/hydrogen exchanger; TrkA-N domain protein; KEGG: scl:sce5468 glutathione-regulated potassium-efflux system protein KefC; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.


ensembl_gene_id: Hden_1622
symbol: Hden_1622
gene_biotype: protein_coding
description:
  Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.


ensembl_gene_id: Hden_1623
symbol: pgk
gene_biotype: protein_coding
description:
  KEGG: mea:Mex_1p2369 phosphoglycerate kinase; PFAM: phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.


ensembl_gene_id: Hden_1624
symbol: Hden_1624
gene_biotype: protein_coding
description:
  PFAM: cytochrome c biogenesis protein transmembrane region; KEGG: rpb:RPB_4376 cytochrome c biogenesis protein, transmembrane region.


ensembl_gene_id: Hden_1625
symbol: Hden_1625
gene_biotype: protein_coding
description:
  KEGG: mno:Mnod_4968 phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1.


ensembl_gene_id: Hden_1626
symbol: Hden_1626
gene_biotype: protein_coding
description:
  PFAM: membrane protein involved in aromatic hydrocarbon degradation; KEGG: met:M446_5803 membrane protein involved in aromatic hydrocarbon degradation.


ensembl_gene_id: Hden_1629
symbol: Hden_1629
gene_biotype: protein_coding
description:
  PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: mno:Mnod_4475 mandelate racemase/muconate lactonizing protein.


ensembl_gene_id: Hden_1633
symbol: Hden_1633
gene_biotype: protein_coding
description:
  PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: bra:BRADO5079 putative thioredoxin reductase, FAD/NAD(P)-binding.


ensembl_gene_id: Hden_1643
symbol: Hden_1643
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF463 YcjX family protein; KEGG: rlg:Rleg_2178 protein of unknown function DUF463 YcjX family protein.


ensembl_gene_id: Hden_1646
symbol: Hden_1646
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function zinc metallopeptidase putative; KEGG: xau:Xaut_1265 protein of unknown function zinc metallopeptidase putative.


ensembl_gene_id: Hden_1648
symbol: glmU
gene_biotype: protein_coding
description:
  UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.


ensembl_gene_id: Hden_1649
symbol: glmS
gene_biotype: protein_coding
description:
  Glucosamine/fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.


ensembl_gene_id: Hden_1652
symbol: Hden_1652
gene_biotype: protein_coding
description:
  KEGG: mlo:mlr0830 ATP-dependent DNA helicase RecG; PFAM: DEAD/DEAH box helicase domain protein; nucleic acid binding OB-fold tRNA/helicase-type; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein.


ensembl_gene_id: Hden_1654
symbol: mfd
gene_biotype: protein_coding
description:
  Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.


ensembl_gene_id: Hden_1656
symbol: Hden_1656
gene_biotype: protein_coding
description:
  PFAM: extracellular solute-binding protein family 5; KEGG: pla:Plav_3093 extracellular solute-binding protein.


ensembl_gene_id: Hden_1658
symbol: Hden_1658
gene_biotype: protein_coding
description:
  KEGG: mrd:Mrad2831_1655 hemimethylated DNA binding protein; TIGRFAM: hemimethylated DNA binding protein; PFAM: Hemimethylated DNA-binding region.


ensembl_gene_id: Hden_1659
symbol: Hden_1659
gene_biotype: protein_coding
description:
  PFAM: HpcH/HpaI aldolase; KEGG: xau:Xaut_3870 HpcH/HpaI aldolase; Belongs to the HpcH/HpaI aldolase family.


ensembl_gene_id: Hden_1664
symbol: Hden_1664
gene_biotype: protein_coding
description:
  Hypothetical protein; KEGG: sce:YER093C Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p), a membrane-associated complex that regulates actin cytoskeletal dynamics during polarized growth and cell wall integrity; involved in sphingolipid metabolism; contains a RasGEFN domain.


ensembl_gene_id: Hden_1668
symbol: Hden_1668
gene_biotype: protein_coding
description:
  KEGG: met:M446_4861 lipid A biosynthesis lauroyl acyltransferase; manually curated; PFAM: lipid A biosynthesis acyltransferase.


ensembl_gene_id: Hden_1669
symbol: Hden_1669
gene_biotype: protein_coding
description:
  KEGG: bja:blr4586 2-octaprenyl-6-methoxyphenyl hydroxylase; TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; PFAM: monooxygenase FAD-binding; fumarate reductase/succinate dehydrogenase flavoprotein domain protein.


ensembl_gene_id: Hden_1680
symbol: Hden_1680
gene_biotype: protein_coding
description:
  KEGG: bph:Bphy_5178 MarR family transcriptional regulator; PFAM: regulatory protein MarR; SMART: regulatory protein MarR.


ensembl_gene_id: Hden_1682
symbol: ispDF
gene_biotype: protein_coding
description:
  2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).


ensembl_gene_id: Hden_1683
symbol: Hden_1683
gene_biotype: protein_coding
description:
  TIM-barrel protein, nifR3 family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.


ensembl_gene_id: Hden_1684
symbol: Hden_1684
gene_biotype: protein_coding
description:
  KEGG: xau:Xaut_4400 signal transduction histidine kinase, nitrogen specific, NtrB; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein.


ensembl_gene_id: Hden_1685
symbol: ntrC
gene_biotype: protein_coding
description:
  Nitrogen metabolism transcriptional regulator, NtrC, Fis Family; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.


ensembl_gene_id: Hden_1686
symbol: Hden_1686
gene_biotype: protein_coding
description:
  Multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; PAS fold domain protein; histidine kinase A domain protein; KEGG: azc:AZC_3084 nitrogen regulation protein NtrY; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; PAS domain containing protein.


ensembl_gene_id: Hden_1687
symbol: Hden_1687
gene_biotype: protein_coding
description:
  KEGG: mno:Mnod_6543 two component, sigma54 specific, transcriptional regulator, fis family; PFAM: sigma-54 factor interaction domain-containing protein; response regulator receiver; helix-turn-helix Fis-type; SMART: response regulator receiver; AAA ATPase.


ensembl_gene_id: Hden_1689
symbol: hfq
gene_biotype: protein_coding
description:
  RNA chaperone Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.


ensembl_gene_id: Hden_1690
symbol: hflX
gene_biotype: protein_coding
description:
  GTP-binding proten HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.


ensembl_gene_id: Hden_1691
symbol: Hden_1691
gene_biotype: protein_coding
description:
  Monooxygenase FAD-binding protein; KEGG: pla:Plav_3170 hypothetical protein; manually curated; PFAM: monooxygenase FAD-binding.


ensembl_gene_id: Hden_1692
symbol: Hden_1692
gene_biotype: protein_coding
description:
  MazG family protein; KEGG: bra:BRADO3851 nucleoside triphosphate pyrophosphohydrolase; TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase.


ensembl_gene_id: Hden_1698
symbol: Hden_1698
gene_biotype: protein_coding
description:
  PFAM: bifunctional deaminase-reductase domain protein; KEGG: rlt:Rleg2_2224 bifunctional deaminase-reductase domain protein.


ensembl_gene_id: Hden_1699
symbol: pepA
gene_biotype: protein_coding
description:
  Leucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.


ensembl_gene_id: Hden_1702
symbol: lptD
gene_biotype: protein_coding
description:
  Organic solvent tolerance protein; Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane; Belongs to the LptD family.


ensembl_gene_id: Hden_1704
symbol: pdxA
gene_biotype: protein_coding
description:
  4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).


ensembl_gene_id: Hden_1705
symbol: rsmA
gene_biotype: protein_coding
description:
  Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.


ensembl_gene_id: Hden_1707
symbol: Hden_1707
gene_biotype: protein_coding
description:
  PFAM: YicC domain protein; domain of unknown function DUF1732; KEGG: mag:amb0747 hypothetical protein.


ensembl_gene_id: Hden_1708
symbol: mltG
gene_biotype: protein_coding
description:
  Aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family.


ensembl_gene_id: Hden_1709
symbol: Hden_1709
gene_biotype: protein_coding
description:
  3-oxoacyl-(acyl-carrier-protein) synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.


ensembl_gene_id: Hden_1711
symbol: Hden_1711
gene_biotype: protein_coding
description:
  3-oxoacyl-(acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: Hden_1712
symbol: Hden_1712
gene_biotype: protein_coding
description:
  KEGG: rpd:RPD_2983 malonyl CoA-acyl carrier protein transacylase; TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase.


ensembl_gene_id: Hden_1713
symbol: Hden_1713
gene_biotype: protein_coding
description:
  PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: nha:Nham_3678 glyoxalase/bleomycin resistance protein/dioxygenase.


ensembl_gene_id: Hden_1717
symbol: rpsR
gene_biotype: protein_coding
description:
  Ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.


ensembl_gene_id: Hden_1720
symbol: Hden_1720
gene_biotype: protein_coding
description:
  Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily.


ensembl_gene_id: Hden_1721
symbol: Hden_1721
gene_biotype: protein_coding
description:
  Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.


ensembl_gene_id: Hden_1722
symbol: radA
gene_biotype: protein_coding
description:
  DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.


ensembl_gene_id: Hden_1724
symbol: purF
gene_biotype: protein_coding
description:
  Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.


ensembl_gene_id: Hden_1725
symbol: Hden_1725
gene_biotype: protein_coding
description:
  PFAM: short-chain dehydrogenase/reductase SDR; KEGG: mno:Mnod_4628 short-chain dehydrogenase/reductase SDR; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: Hden_1728
symbol: Hden_1728
gene_biotype: protein_coding
description:
  Hydrolase, TatD family; KEGG: nwi:Nwi_1461 TatD-related deoxyribonuclease; TIGRFAM: hydrolase, TatD family; PFAM: TatD-related deoxyribonuclease.


ensembl_gene_id: Hden_1729
symbol: metG
gene_biotype: protein_coding
description:
  methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.


ensembl_gene_id: Hden_1731
symbol: tmk
gene_biotype: protein_coding
description:
  Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.


ensembl_gene_id: Hden_1732
symbol: Hden_1732
gene_biotype: protein_coding
description:
  Serine-type D-Ala-D-Ala carboxypeptidase; KEGG: mea:Mex_1p3122 putative penicillin binding protein, beta-lactamase/transpeptidase-like superfamily; PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; Penicillin-binding protein 5 domain protein; Belongs to the peptidase S11 family.


ensembl_gene_id: Hden_1733
symbol: rlpA
gene_biotype: protein_coding
description:
  Rare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.


ensembl_gene_id: Hden_1734
symbol: Hden_1734
gene_biotype: protein_coding
description:
  PFAM: integrase family protein; KEGG: nmu:Nmul_A0922 phage integrase; Belongs to the 'phage' integrase family.


ensembl_gene_id: Hden_1738
symbol: Hden_1738
gene_biotype: protein_coding
description:
  TIGRFAM: phage/plasmid primase, P4 family; PFAM: primase P4; KEGG: dia:Dtpsy_3221 phage/plasmid primase, P4 family; SMART: primase P4.


ensembl_gene_id: Hden_1742
symbol: Hden_1742
gene_biotype: protein_coding
description:
  KEGG: xau:Xaut_4833 CzcA family heavy metal efflux protein; TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: Hden_1743
symbol: Hden_1743
gene_biotype: protein_coding
description:
  KEGG: nwi:Nwi_3130 secretion protein HlyD; TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: Hden_1747
symbol: Hden_1747
gene_biotype: protein_coding
description:
  KEGG: rru:Rru_A1026 MerR family transcriptional regulator; PFAM: Transcription regulator MerR DNA binding; regulatory protein MerR; SMART: regulatory protein MerR.


ensembl_gene_id: Hden_1751
symbol: Hden_1751
gene_biotype: protein_coding
description:
  PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: nha:Nham_0957 TonB-dependent receptor.


ensembl_gene_id: Hden_1754
symbol: Hden_1754
gene_biotype: protein_coding
description:
  PFAM: transport system permease protein; KEGG: nha:Nham_0954 transport system permease protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: Hden_1758
symbol: Hden_1758
gene_biotype: protein_coding
description:
  PFAM: transcriptional regulator PadR family protein; KEGG: sli:Slin_6512 transcriptional regulator, PadR-like family.


ensembl_gene_id: Hden_1763
symbol: Hden_1763
gene_biotype: protein_coding
description:
  Hypothetical protein; KEGG: hut:Huta_2122 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.


ensembl_gene_id: Hden_1766
symbol: Hden_1766
gene_biotype: protein_coding
description:
  KEGG: mno:Mnod_4585 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein.


ensembl_gene_id: Hden_1768
symbol: eno
gene_biotype: protein_coding
description:
  Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.


ensembl_gene_id: Hden_1769
symbol: Hden_1769
gene_biotype: protein_coding
description:
  PFAM: glutathione-dependent formaldehyde-activating GFA; KEGG: ank:AnaeK_3374 glutathione-dependent formaldehyde-activating GFA.


ensembl_gene_id: Hden_1770
symbol: queC
gene_biotype: protein_coding
description:
  exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.


ensembl_gene_id: Hden_1773
symbol: Hden_1773
gene_biotype: protein_coding
description:
  KEGG: dhd:Dhaf_1545 radical SAM domain protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB.


ensembl_gene_id: Hden_1774
symbol: queE
gene_biotype: protein_coding
description:
  Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.


ensembl_gene_id: Hden_1775
symbol: Hden_1775
gene_biotype: protein_coding
description:
  PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: pla:Plav_3150 6-pyruvoyl tetrahydropterin synthase.


ensembl_gene_id: Hden_1776
symbol: queF
gene_biotype: protein_coding
description:
  7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.


ensembl_gene_id: Hden_1781
symbol: thrS
gene_biotype: protein_coding
description:
  threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).


ensembl_gene_id: Hden_1783
symbol: Hden_1783
gene_biotype: protein_coding
description:
  Protein of unknown function DUF37; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family.


ensembl_gene_id: Hden_1786
symbol: folE
gene_biotype: protein_coding
description:
  TIGRFAM: GTP cyclohydrolase I; KEGG: pzu:PHZ_c0417 GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I/Nitrile oxidoreductase.


ensembl_gene_id: Hden_1787
symbol: hisI
gene_biotype: protein_coding
description:
  Phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.


ensembl_gene_id: Hden_1789
symbol: Hden_1789
gene_biotype: protein_coding
description:
  KEGG: pla:Plav_2661 signal-transduction protein; PFAM: CBS domain containing protein; SMART: CBS domain containing protein.


ensembl_gene_id: Hden_1793
symbol: Hden_1793
gene_biotype: protein_coding
description:
  PFAM: transglutaminase family protein cysteine peptidase BTLCP; KEGG: azc:AZC_3670 putative transglutaminase-like cysteine peptidase.


ensembl_gene_id: Hden_1796
symbol: Hden_1796
gene_biotype: protein_coding
description:
  KEGG: rhi:NGR_c13220 serine acetyltransferase, CysE; TIGRFAM: serine O-acetyltransferase; PFAM: serine acetyltransferase domain protein.


ensembl_gene_id: Hden_1797
symbol: Hden_1797
gene_biotype: protein_coding
description:
  PFAM: Enoyl-CoA hydratase/isomerase; KEGG: pla:Plav_2620 enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: Hden_1800
symbol: Hden_1800
gene_biotype: protein_coding
description:
  Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.


ensembl_gene_id: Hden_1802
symbol: Hden_1802
gene_biotype: protein_coding
description:
  TIGRFAM: 5,10-methylenetetrahydrofolate reductase; KEGG: met:M446_4365 5,10-methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.


ensembl_gene_id: Hden_1803
symbol: Hden_1803
gene_biotype: protein_coding
description:
  Transcriptional regulator, ArsR family; KEGG: bmt:BSUIS_A1504 methyltransferase type 11; PFAM: Methyltransferase type 11; regulatory protein ArsR; SMART: regulatory protein ArsR.


ensembl_gene_id: Hden_1808
symbol: Hden_1808
gene_biotype: protein_coding
description:
  KEGG: pla:Plav_2392 putative ABC transporter ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase.


ensembl_gene_id: Hden_1810
symbol: Hden_1810
gene_biotype: protein_coding
description:
  KEGG: rsk:RSKD131_2975 transcriptional regulator, AsnC family; PFAM: Transcription regulator, AsnC-type-like; SMART: Transcription regulator, AsnC-type.


ensembl_gene_id: Hden_1812
symbol: greA
gene_biotype: protein_coding
description:
  Transcription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.


ensembl_gene_id: Hden_1813
symbol: carB
gene_biotype: protein_coding
description:
  TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain oligomerisation; MGS domain protein; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: azc:AZC_1145 carbamoyl-phosphate synthase large subunit; SMART: MGS domain protein; Belongs to the CarB family.


ensembl_gene_id: Hden_1817
symbol: carA
gene_biotype: protein_coding
description:
  KEGG: pla:Plav_2314 carbamoyl-phosphate synthase, small subunit; TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl-phosphate synthase small chain; Belongs to the CarA family.


ensembl_gene_id: Hden_1819
symbol: dnaG
gene_biotype: protein_coding
description:
  DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Belongs to the DnaG primase family.


ensembl_gene_id: Hden_1820
symbol: rpoD
gene_biotype: protein_coding
description:
  RNA polymerase, sigma 70 subunit, RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.


ensembl_gene_id: Hden_1821
symbol: Hden_1821
gene_biotype: protein_coding
description:
  PFAM: Ethyl tert-butyl ether degradation EthD; KEGG: vap:Vapar_4718 ethyl tert-butyl ether degradation EthD.


ensembl_gene_id: Hden_1822
symbol: Hden_1822
gene_biotype: protein_coding
description:
  PFAM: transcription elongation factor GreA/GreB domain protein; KEGG: rpc:RPC_1206 GreA/GreB family elongation factor.


ensembl_gene_id: Hden_1826
symbol: Hden_1826
gene_biotype: protein_coding
description:
  PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: nar:Saro_1044 nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase.


ensembl_gene_id: Hden_1830
symbol: Hden_1830
gene_biotype: protein_coding
description:
  Protein of unknown function DUF454; KEGG: oca:OCAR_6547 membrane protein; manually curated; PFAM: protein of unknown function DUF454.


ensembl_gene_id: Hden_1834
symbol: Hden_1834
gene_biotype: protein_coding
description:
  PFAM: Beta-ketoacyl synthase; KEGG: rru:Rru_A0045 3-oxoacyl-[acyl-carrier-protein] synthase II; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: Hden_1837
symbol: cysS
gene_biotype: protein_coding
description:
  TIGRFAM: cysteinyl-tRNA synthetase; KEGG: bbt:BBta_3498 cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia; Cysteinyl-tRNA synthetase class Ia DALR; Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: Hden_1839
symbol: gltX
gene_biotype: protein_coding
description:
  glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.


ensembl_gene_id: Hden_1840
symbol: nadE
gene_biotype: protein_coding
description:
  NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.


ensembl_gene_id: Hden_1843
symbol: Hden_1843
gene_biotype: protein_coding
description:
  TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; KEGG: mes:Meso_1462 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase; PFAM: DAHP synthetase class II.


ensembl_gene_id: Hden_1844
symbol: Hden_1844
gene_biotype: protein_coding
description:
  PFAM: short-chain dehydrogenase/reductase SDR; KEGG: eat:EAT1b_1814 short-chain dehydrogenase/reductase SDR.


ensembl_gene_id: Hden_1847
symbol: rpiA
gene_biotype: protein_coding
description:
  Ribose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.


ensembl_gene_id: Hden_1848
symbol: gph
gene_biotype: protein_coding
description:
  Phosphoglycolate phosphatase; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.


ensembl_gene_id: Hden_1853
symbol: Hden_1853
gene_biotype: protein_coding
description:
  PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: pzu:PHZ_c3319 ornithine decarboxylase; Belongs to the Orn/Lys/Arg decarboxylase class-II family.


ensembl_gene_id: Hden_1856
symbol: Hden_1856
gene_biotype: protein_coding
description:
  KEGG: bja:bll4731 threonine dehydratase; TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein.


ensembl_gene_id: Hden_1858
symbol: Hden_1858
gene_biotype: protein_coding
description:
  3-hydroxyisobutyrate dehydrogenase; KEGG: bmr:BMI_I948 oxidoreductase, putative; PFAM: 6-phosphogluconate dehydrogenase NAD-binding.


ensembl_gene_id: Hden_1859
symbol: Hden_1859
gene_biotype: protein_coding
description:
  KEGG: bmr:BMI_I865 transcriptional regulator, AsnC family; PFAM: Transcription regulator, AsnC-type-like; SMART: Transcription regulator, AsnC-type.


ensembl_gene_id: Hden_1862
symbol: Hden_1862
gene_biotype: protein_coding
description:
  KEGG: rpb:RPB_3395 periplasmic sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein.


ensembl_gene_id: Hden_1863
symbol: Hden_1863
gene_biotype: protein_coding
description:
  Aspartyl protease-like protein; KEGG: mrd:Mrad2831_1975 putative transmembrane signal peptide protein.


ensembl_gene_id: Hden_1865
symbol: Hden_1865
gene_biotype: protein_coding
description:
  PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase; KEGG: pla:Plav_1053 phosphoglucomutase/phosphomannomutase alpha/beta/subunit.


ensembl_gene_id: Hden_1867
symbol: dusA
gene_biotype: protein_coding
description:
  TIM-barrel protein, yjbN family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily.


ensembl_gene_id: Hden_1868
symbol: Hden_1868
gene_biotype: protein_coding
description:
  PFAM: MOSC domain containing protein; 3-alpha domain protein; KEGG: xau:Xaut_5027 MOSC domain-containing protein.


ensembl_gene_id: Hden_1869
symbol: Hden_1869
gene_biotype: protein_coding
description:
  TIGRFAM: PQQ-dependent dehydrogenase, methanol/ethanol family; PFAM: PQQ-dependent enzyme-like; Pyrrolo-quinoline quinone; KEGG: mrd:Mrad2831_0508 methanol/ethanol family PQQ-dependent dehydrogenase; SMART: Pyrrolo-quinoline quinone beta-propeller repeat.


ensembl_gene_id: Hden_1870
symbol: Hden_1870
gene_biotype: protein_coding
description:
  Transcriptional regulator, GntR family with aminotransferase domain protein; KEGG: nhl:Nhal_1084 regulatory protein GntR HTH; PFAM: regulatory protein GntR HTH; aminotransferase class I and II; SMART: regulatory protein GntR HTH.


ensembl_gene_id: Hden_1871
symbol: Hden_1871
gene_biotype: protein_coding
description:
  Transcriptional regulator, Crp/Fnr family; KEGG: mlo:mll6632 Fnr-type transcriptional regulator; PFAM: regulatory protein Crp; cyclic nucleotide-binding; SMART: regulatory protein Crp; cyclic nucleotide-binding.


ensembl_gene_id: Hden_1875
symbol: Hden_1875
gene_biotype: protein_coding
description:
  KEGG: mno:Mnod_4915 formaldehyde-activating enzyme; TIGRFAM: formaldehyde-activating enzyme; PFAM: Formaldehyde-activating enzyme (Fae).


ensembl_gene_id: Hden_1877
symbol: Hden_1877
gene_biotype: protein_coding
description:
  ApbE family lipoprotein; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. Belongs to the ApbE family.


ensembl_gene_id: Hden_1880
symbol: Hden_1880
gene_biotype: protein_coding
description:
  KEGG: bbt:BBta_6010 copper ABC transporter, ATP-binding protein NosF; PFAM: ABC transporter related; SMART: AAA ATPase.


ensembl_gene_id: Hden_1881
symbol: Hden_1881
gene_biotype: protein_coding
description:
  KEGG: bja:blr0316 periplasmic copper-binding precursor; PFAM: periplasmic copper-binding; SMART: Carbohydrate-binding and sugar hydrolysis; Parallel beta-helix repeat.


ensembl_gene_id: Hden_1882
symbol: nosZ
gene_biotype: protein_coding
description:
  Nitrous-oxide reductase; Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide; In the C-terminal section; belongs to the cytochrome c oxidase subunit 2 family.


ensembl_gene_id: Hden_1883
symbol: Hden_1883
gene_biotype: protein_coding
description:
  Nitrous oxide expression regulator, NosR; PFAM: FMN-binding domain protein; KEGG: met:M446_2862 FMN-binding domain-containing protein.


ensembl_gene_id: Hden_1885
symbol: Hden_1885
gene_biotype: protein_coding
description:
  KEGG: kfl:Kfla_4282 two component transcriptional regulator, LuxR family; PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR.


ensembl_gene_id: Hden_1887
symbol: Hden_1887
gene_biotype: protein_coding
description:
  TIGRFAM: outer membrane autotransporter barrel domain protein; PFAM: Autotransporter beta- domain protein; Pertactin; KEGG: xau:Xaut_2793 outer membrane autotransporter; SMART: Autotransporter beta- domain protein.


ensembl_gene_id: Hden_1892
symbol: pdxH
gene_biotype: protein_coding
description:
  Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).


ensembl_gene_id: Hden_1901
symbol: lexA
gene_biotype: protein_coding
description:
  Transcriptional repressor, LexA family; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.


ensembl_gene_id: Hden_1902
symbol: Hden_1902
gene_biotype: protein_coding
description:
  KEGG: pla:Plav_3179 ComEC/Rec2-related protein; TIGRFAM: ComEC/Rec2-related protein; PFAM: ComEC/Rec2-related protein.


ensembl_gene_id: Hden_1904
symbol: Hden_1904
gene_biotype: protein_coding
description:
  KEGG: sme:SMc02087 type II citrate synthase; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; Belongs to the citrate synthase family.


ensembl_gene_id: Hden_1905
symbol: lpxB
gene_biotype: protein_coding
description:
  lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: Hden_1907
symbol: lpxA
gene_biotype: protein_coding
description:
  acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: Hden_1908
symbol: fabZ
gene_biotype: protein_coding
description:
  Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.


ensembl_gene_id: Hden_1909
symbol: lpxD
gene_biotype: protein_coding
description:
  UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily.


ensembl_gene_id: Hden_1910
symbol: bamA
gene_biotype: protein_coding
description:
  Outer membrane protein assembly complex, YaeT protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: Hden_1911
symbol: Hden_1911
gene_biotype: protein_coding
description:
  TIGRFAM: membrane-associated zinc metalloprotease; PFAM: peptidase M50; PDZ/DHR/GLGF domain protein; KEGG: rpt:Rpal_3261 membrane-associated zinc metalloprotease; SMART: PDZ/DHR/GLGF domain protein.


ensembl_gene_id: Hden_1912
symbol: dxr
gene_biotype: protein_coding
description:
  1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family.


ensembl_gene_id: Hden_1913
symbol: Hden_1913
gene_biotype: protein_coding
description:
  PFAM: phosphatidate cytidylyltransferase; KEGG: xau:Xaut_4434 phosphatidate cytidylyltransferase; Belongs to the CDS family.


ensembl_gene_id: Hden_1914
symbol: Hden_1914
gene_biotype: protein_coding
description:
  Undecaprenyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.


ensembl_gene_id: Hden_1915
symbol: frr
gene_biotype: protein_coding
description:
  Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.


ensembl_gene_id: Hden_1917
symbol: tsf
gene_biotype: protein_coding
description:
  Translation elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.


ensembl_gene_id: Hden_1918
symbol: rpsB
gene_biotype: protein_coding
description:
  KEGG: rpc:RPC_2436 30S ribosomal protein S2; TIGRFAM: ribosomal protein S2; PFAM: ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.


ensembl_gene_id: Hden_1921
symbol: Hden_1921
gene_biotype: protein_coding
description:
  DNA polymerase III, alpha subunit; SMART: phosphoesterase PHP domain protein; TIGRFAM: DNA polymerase III, alpha subunit; KEGG: bbt:BBta_4522 DNA polymerase III subunit alpha; PFAM: DNA polymerase III alpha subunit; nucleic acid binding OB-fold tRNA/helicase-type; PHP domain protein.


ensembl_gene_id: Hden_1922
symbol: lolD
gene_biotype: protein_coding
description:
  ABC transporter related protein; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.


ensembl_gene_id: Hden_1923
symbol: Hden_1923
gene_biotype: protein_coding
description:
  KEGG: nha:Nham_2196 LolC/E family lipoprotein releasing system, transmembrane protein; TIGRFAM: lipoprotein releasing system, transmembrane protein, LolC/E family; PFAM: protein of unknown function DUF214.


ensembl_gene_id: Hden_1924
symbol: proS
gene_biotype: protein_coding
description:
  prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).


ensembl_gene_id: Hden_1926
symbol: Hden_1926
gene_biotype: protein_coding
description:
  TIGRFAM: methylmalonyl-CoA epimerase; KEGG: mno:Mnod_4142 methylmalonyl-CoA epimerase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase.


ensembl_gene_id: Hden_1927
symbol: Hden_1927
gene_biotype: protein_coding
description:
  KEGG: bbt:BBta_4546 metallo-beta-lactamase family hydrolase; PFAM: RNA-metabolising metallo-beta-lactamase; SMART: beta-lactamase domain protein.


ensembl_gene_id: Hden_1928
symbol: Hden_1928
gene_biotype: protein_coding
description:
  KEGG: pla:Plav_3212 biotin--acetyl-CoA-carboxylase ligase; TIGRFAM: biotin/acetyl-CoA-carboxylase ligase; PFAM: biotin/lipoate A/B protein ligase; biotin protein ligase domain protein.


ensembl_gene_id: Hden_1929
symbol: nuoN
gene_biotype: protein_coding
description:
  Proton-translocating NADH-quinone oxidoreductase, chain N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family.


ensembl_gene_id: Hden_1930
symbol: Hden_1930
gene_biotype: protein_coding
description:
  KEGG: pla:Plav_3214 proton-translocating NADH-quinone oxidoreductase, chain M; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain M; PFAM: NADH/Ubiquinone/plastoquinone (complex I).


ensembl_gene_id: Hden_1931
symbol: Hden_1931
gene_biotype: protein_coding
description:
  KEGG: azc:AZC_1679 NADH-plastoquinone oxidoreductase chain 5 protein; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain L; PFAM: NADH/Ubiquinone/plastoquinone (complex I); NADH-Ubiquinone oxidoreductase (complex I) chain 5/L domain protein.


ensembl_gene_id: Hden_1932
symbol: nuoK
gene_biotype: protein_coding
description:
  NADH-ubiquinone oxidoreductase chain 4L; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family.


ensembl_gene_id: Hden_1933
symbol: Hden_1933
gene_biotype: protein_coding
description:
  NADH-ubiquinone/plastoquinone oxidoreductase chain 6; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: Hden_1934
symbol: nuoI
gene_biotype: protein_coding
description:
  NADH-quinone oxidoreductase, chain I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: Hden_1935
symbol: nuoH
gene_biotype: protein_coding
description:
  Respiratory-chain NADH dehydrogenase subunit 1; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.


ensembl_gene_id: Hden_1936
symbol: Hden_1936
gene_biotype: protein_coding
description:
  NADH-quinone oxidoreductase, chain G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family.


ensembl_gene_id: Hden_1937
symbol: Hden_1937
gene_biotype: protein_coding
description:
  NADH-quinone oxidoreductase, F subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family.


ensembl_gene_id: Hden_1938
symbol: Hden_1938
gene_biotype: protein_coding
description:
  TIGRFAM: NADH-quinone oxidoreductase, E subunit; KEGG: sil:SPO2780 NADH dehydrogenase subunit E; PFAM: NADH dehydrogenase (ubiquinone) 24 kDa subunit.


ensembl_gene_id: Hden_1940
symbol: nuoD
gene_biotype: protein_coding
description:
  NADH dehydrogenase I, D subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family.


ensembl_gene_id: Hden_1943
symbol: nuoC
gene_biotype: protein_coding
description:
  NADH (or F420H2) dehydrogenase, subunit C; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 30 kDa subunit family.


ensembl_gene_id: Hden_1945
symbol: nuoB
gene_biotype: protein_coding
description:
  NADH-quinone oxidoreductase, B subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: Hden_1946
symbol: nuoA
gene_biotype: protein_coding
description:
  NADH-ubiquinone/plastoquinone oxidoreductase chain 3; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family.


ensembl_gene_id: Hden_1950
symbol: Hden_1950
gene_biotype: protein_coding
description:
  Adenylate/guanylate cyclase with Chase sensor; KEGG: xau:Xaut_1894 putative CHASE2 sensor protein; PFAM: CHASE2 domain protein; adenylyl cyclase class-3/4/guanylyl cyclase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase.


ensembl_gene_id: Hden_1952
symbol: Hden_1952
gene_biotype: protein_coding
description:
  TIGRFAM: diguanylate cyclase; PFAM: EAL domain protein; GGDEF domain containing protein; KEGG: bbt:BBta_4485 diguanylate cyclase/phosphodiesterase; SMART: EAL domain protein; GGDEF domain containing protein.


ensembl_gene_id: Hden_1955
symbol: Hden_1955
gene_biotype: protein_coding
description:
  KEGG: ftm:FTM_0702 DNA-binding protein HU-beta; PFAM: histone family protein DNA-binding protein; SMART: histone family protein DNA-binding protein; Belongs to the bacterial histone-like protein family.


ensembl_gene_id: Hden_1956
symbol: lon
gene_biotype: protein_coding
description:
  ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.


ensembl_gene_id: Hden_1957
symbol: clpX
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.


ensembl_gene_id: Hden_1958
symbol: clpP
gene_biotype: protein_coding
description:
  Endopeptidase Clp; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.


ensembl_gene_id: Hden_1959
symbol: tig
gene_biotype: protein_coding
description:
  Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.


ensembl_gene_id: Hden_1960
symbol: Hden_1960
gene_biotype: protein_coding
description:
  KEGG: rhodanese domain-containing protein; PFAM: Rhodanese domain protein; SMART: Rhodanese domain protein.


ensembl_gene_id: Hden_1961
symbol: Hden_1961
gene_biotype: protein_coding
description:
  PFAM: glutathione peroxidase; KEGG: azl:AZL_027970 glutathione peroxidase; Belongs to the glutathione peroxidase family.


ensembl_gene_id: Hden_1968
symbol: Hden_1968
gene_biotype: protein_coding
description:
  Protein of unknown function DUF214; KEGG: bra:BRADO0993 putative ABC transporter, permease protein; manually curated; PFAM: protein of unknown function DUF214.


ensembl_gene_id: Hden_1970
symbol: Hden_1970
gene_biotype: protein_coding
description:
  PFAM: short-chain dehydrogenase/reductase SDR; KEGG: pla:Plav_0786 short-chain dehydrogenase/reductase SDR.


ensembl_gene_id: Hden_1971
symbol: Hden_1971
gene_biotype: protein_coding
description:
  PFAM: Phosphoglycerate mutase; KEGG: rhi:NGR_c05180 phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family.


ensembl_gene_id: Hden_1972
symbol: aroC
gene_biotype: protein_coding
description:
  Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.


ensembl_gene_id: Hden_1974
symbol: Hden_1974
gene_biotype: protein_coding
description:
  PFAM: (Uracil-5)-methyltransferase; KEGG: hne:HNE_2781 putative 23S rRNA (uracil-5-)-methyltransferase RumA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.


ensembl_gene_id: Hden_1975
symbol: Hden_1975
gene_biotype: protein_coding
description:
  SMART: RNA-binding S4 domain protein; manually curated; TIGRFAM: hemolysin A; KEGG: rru:Rru_A2620 hemolysin A; PFAM: ribosomal RNA methyltransferase RrmJ/FtsJ; RNA-binding S4 domain protein.


ensembl_gene_id: Hden_1978
symbol: xseB
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease VII, small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.


ensembl_gene_id: Hden_1983
symbol: Hden_1983
gene_biotype: protein_coding
description:
  Sua5/YciO/YrdC/YwlC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.


ensembl_gene_id: Hden_1987
symbol: Hden_1987
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF159; KEGG: rhi:NGR_c08610 hypothetical protein; Belongs to the SOS response-associated peptidase family.


ensembl_gene_id: Hden_1993
symbol: Hden_1993
gene_biotype: protein_coding
description:
  TIGRFAM: dihydroorotase, multifunctional complex type; KEGG: rpb:RPB_1118 dihydroorotase; PFAM: amidohydrolase.


ensembl_gene_id: Hden_1994
symbol: Hden_1994
gene_biotype: protein_coding
description:
  KEGG: mrd:Mrad2831_3987 folate-binding protein YgfZ; TIGRFAM: folate-binding protein YgfZ; PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel; Belongs to the GcvT family.


ensembl_gene_id: Hden_1995
symbol: Hden_1995
gene_biotype: protein_coding
description:
  TIGRFAM: DNA-3-methyladenine glycosylase I; KEGG: rpc:RPC_4332 DNA-3-methyladenine glycosylase I; PFAM: methyladenine glycosylase.


ensembl_gene_id: Hden_1996
symbol: Hden_1996
gene_biotype: protein_coding
description:
  KEGG: rpd:RPD_1235 metal-dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region.


ensembl_gene_id: Hden_1998
symbol: nadA
gene_biotype: protein_coding
description:
  Quinolinate synthetase complex, A subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.


ensembl_gene_id: Hden_2000
symbol: Hden_2000
gene_biotype: protein_coding
description:
  TIGRFAM: nicotinate-nucleotide pyrophosphorylase; KEGG: oan:Oant_0431 nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase; Belongs to the NadC/ModD family.


ensembl_gene_id: Hden_2002
symbol: Hden_2002
gene_biotype: protein_coding
description:
  TIGRFAM: pyruvate, phosphate dikinase; KEGG: xau:Xaut_0494 pyruvate phosphate dikinase; PFAM: pyruvate phosphate dikinase PEP/pyruvate-binding; PEP-utilizing protein; PEP-utilising protein mobile region; Belongs to the PEP-utilizing enzyme family.


ensembl_gene_id: Hden_2003
symbol: Hden_2003
gene_biotype: protein_coding
description:
  PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: atc:AGR_C_165 hypothetical protein.


ensembl_gene_id: Hden_2007
symbol: Hden_2007
gene_biotype: protein_coding
description:
  PFAM: short-chain dehydrogenase/reductase SDR; KEGG: mes:Meso_1974 short chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: Hden_2011
symbol: uvrC
gene_biotype: protein_coding
description:
  Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.


ensembl_gene_id: Hden_2013
symbol: Hden_2013
gene_biotype: protein_coding
description:
  KEGG: mno:Mnod_3714 CDP-diacylglycerol/glycerol-3-phosphate 3-phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol/glycerol-3-phosphate 3-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: Hden_2014
symbol: Hden_2014
gene_biotype: protein_coding
description:
  KEGG: mrd:Mrad2831_5403 molybdopterin converting factor, subunit 1; TIGRFAM: molybdopterin converting factor, subunit 1; PFAM: thiamineS protein.


ensembl_gene_id: Hden_2015
symbol: Hden_2015
gene_biotype: protein_coding
description:
  PFAM: molybdopterin biosynthesis MoaE protein; KEGG: dar:Daro_2729 molybdopterin synthase subunit MoaE.


ensembl_gene_id: Hden_2016
symbol: Hden_2016
gene_biotype: protein_coding
description:
  Cell wall hydrolase/autolysin; KEGG: rpc:RPC_2853 N-acetylmuramoyl-L-alanine amidase; PFAM: cell wall hydrolase/autolysin; SMART: cell wall hydrolase/autolysin.


ensembl_gene_id: Hden_2017
symbol: Hden_2017
gene_biotype: protein_coding
description:
  PFAM: diacylglycerol kinase catalytic region; KEGG: pla:Plav_1994 diacylglycerol kinase catalytic region.


ensembl_gene_id: Hden_2018
symbol: rpoH
gene_biotype: protein_coding
description:
  RNA polymerase, sigma 32 subunit, RpoH; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.


ensembl_gene_id: Hden_2024
symbol: Hden_2024
gene_biotype: protein_coding
description:
  Calcium/proton antiporter, CaCA family; Ca(+)/H(+) antiporter that extrudes calcium in exchange for external protons.


ensembl_gene_id: Hden_2025
symbol: Hden_2025
gene_biotype: protein_coding
description:
  Manually curated; TIGRFAM: sulfate transporter; KEGG: bja:blr2848 sulphate transport protein; PFAM: sulphate transporter; Sulfate transporter/antisigma-factor antagonist STAS.


ensembl_gene_id: Hden_2029
symbol: ackA
gene_biotype: protein_coding
description:
  Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.


ensembl_gene_id: Hden_2032
symbol: Hden_2032
gene_biotype: protein_coding
description:
  KEGG: bja:bll5080 AcrB/AcrD/AcrF family protein; TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein.


ensembl_gene_id: Hden_2033
symbol: Hden_2033
gene_biotype: protein_coding
description:
  Efflux transporter, RND family, MFP subunit; KEGG: bja:bll5081 putative multidrug resistance protein; TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: Hden_2037
symbol: Hden_2037
gene_biotype: protein_coding
description:
  Transcriptional regulator, LuxR family; KEGG: xau:Xaut_0924 response regulator receiver protein; PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR.


ensembl_gene_id: Hden_2043
symbol: Hden_2043
gene_biotype: protein_coding
description:
  KEGG: rpd:RPD_0737 cytochrome oxidase maturation protein, cbb3-type; TIGRFAM: cytochrome oxidase maturation protein, cbb3-type; PFAM: cytochrome oxidase maturation protein cbb3-type.


ensembl_gene_id: Hden_2044
symbol: Hden_2044
gene_biotype: protein_coding
description:
  KEGG: pla:Plav_1526 heavy metal translocating P-type ATPase; TIGRFAM: heavy metal translocating P-type ATPase; copper-translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase-associated domain protein; Heavy metal transport/detoxification protein; Haloacid dehalogenase domain protein hydrolase.


ensembl_gene_id: Hden_2046
symbol: Hden_2046
gene_biotype: protein_coding
description:
  KEGG: pla:Plav_1528 cytochrome c oxidase cbb3 type accessory protein FixG; TIGRFAM: cytochrome c oxidase accessory protein CcoG; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein.


ensembl_gene_id: Hden_2047
symbol: Hden_2047
gene_biotype: protein_coding
description:
  Cytochrome c oxidase, cbb3-type, subunit III; C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.


ensembl_gene_id: Hden_2048
symbol: Hden_2048
gene_biotype: protein_coding
description:
  PFAM: Cbb3-type cytochrome oxidase component; KEGG: hne:HNE_1230 cytochrome c oxidase, cbb3-type, CcoQ subunit.


ensembl_gene_id: Hden_2049
symbol: Hden_2049
gene_biotype: protein_coding
description:
  KEGG: rpb:RPB_0016 cytochrome c oxidase, cbb3-type, subunit II; TIGRFAM: cytochrome c oxidase, cbb3-type, subunit II; PFAM: cytochrome C oxidase mono-heme subunit/FixO.


ensembl_gene_id: Hden_2050
symbol: Hden_2050
gene_biotype: protein_coding
description:
  TIGRFAM: cytochrome c oxidase, cbb3-type, subunit I; KEGG: pla:Plav_1532 cytochrome c oxidase, cbb3-type, subunit I; PFAM: cytochrome c oxidase subunit I; Belongs to the heme-copper respiratory oxidase family.


ensembl_gene_id: Hden_2051
symbol: Hden_2051
gene_biotype: protein_coding
description:
  PFAM: short-chain dehydrogenase/reductase SDR; KEGG: bxe:Bxe_C0050 enoyl-(acyl carrier protein) reductase.


ensembl_gene_id: Hden_2053
symbol: Hden_2053
gene_biotype: protein_coding
description:
  Phosphate acetyltransferase; KEGG: azc:AZC_2420 bifunctional enoyl-CoA hydratase/phosphate acetyltransferase; PFAM: MaoC domain protein dehydratase; phosphate acetyl/butaryl transferase.


ensembl_gene_id: Hden_2054
symbol: Hden_2054
gene_biotype: protein_coding
description:
  PFAM: Poly-beta-hydroxybutyrate polymerase domain protein; alpha/beta hydrolase fold; KEGG: bxe:Bxe_C0053 putative poly-beta-hydroxybutyrate polymerase.


ensembl_gene_id: Hden_2055
symbol: metE
gene_biotype: protein_coding
description:
  5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.


ensembl_gene_id: Hden_2058
symbol: Hden_2058
gene_biotype: protein_coding
description:
  KEGG: bcs:BCAN_A1651 isocitrate lyase; TIGRFAM: isocitrate lyase; PFAM: isocitrate lyase and phosphorylmutase.


ensembl_gene_id: Hden_2059
symbol: Hden_2059
gene_biotype: protein_coding
description:
  KEGG: rru:Rru_A2316 XRE family transcriptional regulator; PFAM: Protein of unknown function DUF2083,transcriptional regulator; protein of unknown function DUF955; helix-turn-helix domain protein; SMART: helix-turn-helix domain protein.


ensembl_gene_id: Hden_2072
symbol: leuA
gene_biotype: protein_coding
description:
  2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.


ensembl_gene_id: Hden_2074
symbol: Hden_2074
gene_biotype: protein_coding
description:
  KEGG: smd:Smed_1932 PhzF family phenazine biosynthesis protein; TIGRFAM: phenazine biosynthesis protein PhzF family; PFAM: Phenazine biosynthesis PhzC/PhzF protein.


ensembl_gene_id: Hden_2076
symbol: ilvC
gene_biotype: protein_coding
description:
  Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.


ensembl_gene_id: Hden_2077
symbol: Hden_2077
gene_biotype: protein_coding
description:
  KEGG: mes:Meso_1489 acetolactate synthase 3 regulatory subunit; TIGRFAM: acetolactate synthase, small subunit; PFAM: Acetolactate synthase, small subunit-like; amino acid-binding ACT domain protein.


ensembl_gene_id: Hden_2078
symbol: Hden_2078
gene_biotype: protein_coding
description:
  PFAM: Glutathione S-transferase domain; KEGG: bbt:BBta_4787 putative glutathione S-transferase (GST).


ensembl_gene_id: Hden_2079
symbol: Hden_2079
gene_biotype: protein_coding
description:
  Hypothetical protein; KEGG: bmr:BMI_I1357 iron compound ABC transporter, periplasmic iron compound-binding protein.


ensembl_gene_id: Hden_2080
symbol: Hden_2080
gene_biotype: protein_coding
description:
  KEGG: xau:Xaut_1488 acetolactate synthase, large subunit, biosynthetic type; TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate protein TPP binding domain protein; thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region.


ensembl_gene_id: Hden_2081
symbol: miaA
gene_biotype: protein_coding
description:
  tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.


ensembl_gene_id: Hden_2084
symbol: Hden_2084
gene_biotype: protein_coding
description:
  Pseudoazurin; KEGG: mes:Meso_4276 pseudoazurin; TIGRFAM: pseudoazurin; PFAM: blue (type 1) copper domain protein.


ensembl_gene_id: Hden_2085
symbol: Hden_2085
gene_biotype: protein_coding
description:
  KEGG: mea:Mex_1p5196 putative ABC transporter, fused ATPase and permease domains; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase.


ensembl_gene_id: Hden_2086
symbol: Hden_2086
gene_biotype: protein_coding
description:
  KEGG: ddi:DDBDRAFT_0216653 hypothetical protein; PFAM: Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding LysM.


ensembl_gene_id: Hden_2087
symbol: Hden_2087
gene_biotype: protein_coding
description:
  PFAM: conserved hypothetical protein; KEGG: mno:Mnod_1637 hypothetical protein; Belongs to the LOG family.


ensembl_gene_id: Hden_2088
symbol: Hden_2088
gene_biotype: protein_coding
description:
  TIGRFAM: LAO/AO transport system ATPase; PFAM: ArgK protein; KEGG: xau:Xaut_5042 LAO/AO transport system ATPase; SMART: AAA ATPase.


ensembl_gene_id: Hden_2092
symbol: Hden_2092
gene_biotype: protein_coding
description:
  KEGG: rlt:Rleg2_1921 adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase-like; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.


ensembl_gene_id: Hden_2093
symbol: Hden_2093
gene_biotype: protein_coding
description:
  KEGG: azo:azo2163 hypothetical protein; PFAM: phosphoesterase PA-phosphatase related; SMART: phosphoesterase PA-phosphatase related.


ensembl_gene_id: Hden_2094
symbol: Hden_2094
gene_biotype: protein_coding
description:
  Dolichyl-phosphate beta-D-mannosyltransferase; KEGG: bbt:BBta_5297 putative dolichol-phosphate mannosyltransferase; PFAM: glycosyl transferase family 2; GtrA family protein.


ensembl_gene_id: Hden_2099
symbol: purC
gene_biotype: protein_coding
description:
  TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; KEGG: bbt:BBta_5409 phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase.


ensembl_gene_id: Hden_2100
symbol: purS
gene_biotype: protein_coding
description:
  Phosphoribosylformylglycinamidine synthase, purS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assi [...]


ensembl_gene_id: Hden_2102
symbol: purQ
gene_biotype: protein_coding
description:
  Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...]


ensembl_gene_id: Hden_2104
symbol: Hden_2104
gene_biotype: protein_coding
description:
  PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: rlg:Rleg_2347 glyoxalase/bleomycin resistance protein/dioxygenase.


ensembl_gene_id: Hden_2106
symbol: purL
gene_biotype: protein_coding
description:
  Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist  [...]


ensembl_gene_id: Hden_2111
symbol: Hden_2111
gene_biotype: protein_coding
description:
  PFAM: BolA family protein; KEGG: met:M446_0006 BolA family protein; Belongs to the BolA/IbaG family.


ensembl_gene_id: Hden_2112
symbol: Hden_2112
gene_biotype: protein_coding
description:
  Glutaredoxin-like protein; KEGG: sjp:SJA_C1-28240 monothiol glutaredoxin; TIGRFAM: glutaredoxin-like protein; PFAM: glutaredoxin; Belongs to the glutaredoxin family. Monothiol subfamily.


ensembl_gene_id: Hden_2113
symbol: Hden_2113
gene_biotype: protein_coding
description:
  KEGG: bja:blr6726 AcrB/AcrD/AcrF family protein; TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein.


ensembl_gene_id: Hden_2114
symbol: Hden_2114
gene_biotype: protein_coding
description:
  Efflux transporter, RND family, MFP subunit; KEGG: bja:blr6725 putative multidrug resistance protein; TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: Hden_2118
symbol: rpsD
gene_biotype: protein_coding
description:
  Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.


ensembl_gene_id: Hden_2121
symbol: Hden_2121
gene_biotype: protein_coding
description:
  Isocitrate dehydrogenase, NADP-dependent; KEGG: rlt:Rleg2_1953 isocitrate dehydrogenase; TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: isocitrate/isopropylmalate dehydrogenase; Belongs to the isocitrate and isopropylmalate dehydrogenases family.


ensembl_gene_id: Hden_2124
symbol: alaS
gene_biotype: protein_coding
description:
  alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.


ensembl_gene_id: Hden_2125
symbol: recA
gene_biotype: protein_coding
description:
  recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.


ensembl_gene_id: Hden_2126
symbol: Hden_2126
gene_biotype: protein_coding
description:
  KEGG: mfa:Mfla_2364 putative formaldehyde-activating enzyme; TIGRFAM: formaldehyde-activating enzyme; PFAM: Formaldehyde-activating enzyme (Fae).


ensembl_gene_id: Hden_2127
symbol: Hden_2127
gene_biotype: protein_coding
description:
  Multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; PAS fold-4 domain protein; histidine kinase A domain protein; KEGG: rpt:Rpal_4405 multi-sensor hybrid histidine kinase; SMART: ATP-binding region ATPase domain protein; response regulator receiver; PAS domain containing protein; histidine kinase A domain protein.


ensembl_gene_id: Hden_2130
symbol: dksA
gene_biotype: protein_coding
description:
  Transcriptional regulator, TraR/DksA family; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.


ensembl_gene_id: Hden_2131
symbol: Hden_2131
gene_biotype: protein_coding
description:
  KEGG: rpe:RPE_2031 ATPase; PFAM: ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase.


ensembl_gene_id: Hden_2133
symbol: Hden_2133
gene_biotype: protein_coding
description:
  TIGRFAM: asparagine synthase (glutamine-hydrolyzing); KEGG: scl:sce2064 asparagine synthetase; PFAM: asparagine synthase; glutamine amidotransferase class-II.


ensembl_gene_id: Hden_2135
symbol: Hden_2135
gene_biotype: protein_coding
description:
  PFAM: secretion protein HlyD family protein; KEGG: rhi:NGR_c29530 putative multidrug resistance protein.


ensembl_gene_id: Hden_2136
symbol: Hden_2136
gene_biotype: protein_coding
description:
  Drug resistance transporter, EmrB/QacA subfamily; KEGG: mlo:mlr4819 multidrug resistance protein B (drug efflux transporter); TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1.


ensembl_gene_id: Hden_2137
symbol: Hden_2137
gene_biotype: protein_coding
description:
  PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: nwi:Nwi_3051 TonB-dependent receptor.


ensembl_gene_id: Hden_2140
symbol: Hden_2140
gene_biotype: protein_coding
description:
  Putative periplasmic ligand-binding sensor protein; PFAM: Protein of unknown function DUF2076; KEGG: rle:RL3516 hypothetical protein.


ensembl_gene_id: Hden_2147
symbol: Hden_2147
gene_biotype: protein_coding
description:
  PFAM: General secretion pathway protein M; KEGG: alv:Alvin_3008 general secretion pathway protein M.


ensembl_gene_id: Hden_2152
symbol: Hden_2152
gene_biotype: protein_coding
description:
  TIGRFAM: general secretion pathway protein H; KEGG: bbt:BBta_1281 putative general secretion pathway protein H, GspH.


ensembl_gene_id: Hden_2153
symbol: Hden_2153
gene_biotype: protein_coding
description:
  KEGG: nhl:Nhal_0441 general secretion pathway protein G; TIGRFAM: general secretion pathway protein G; PFAM: type II secretion system protein G.


ensembl_gene_id: Hden_2155
symbol: Hden_2155
gene_biotype: protein_coding
description:
  KEGG: bja:bll6021 general secretion pathway protein E; PFAM: type II secretion system protein E; General secretory system II protein E domain protein; SMART: AAA ATPase.


ensembl_gene_id: Hden_2156
symbol: Hden_2156
gene_biotype: protein_coding
description:
  KEGG: xau:Xaut_2106 general secretion pathway protein D; TIGRFAM: general secretion pathway protein D; PFAM: type II and III secretion system protein; NolW domain protein; Belongs to the bacterial secretin family.


ensembl_gene_id: Hden_2157
symbol: Hden_2157
gene_biotype: protein_coding
description:
  PFAM: peptidase A24A prepilin type IV; KEGG: bja:blr6023 prepilin peptidase; Belongs to the peptidase A24 family.


ensembl_gene_id: Hden_2158
symbol: Hden_2158
gene_biotype: protein_coding
description:
  KEGG: bra:BRADO3285 AraC/XylS family transcription factor; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain.


ensembl_gene_id: Hden_2159
symbol: Hden_2159
gene_biotype: protein_coding
description:
  PFAM: Carboxylesterase type B; KEGG: msl:Msil_2379 carboxylesterase type B; Belongs to the type-B carboxylesterase/lipase family.


ensembl_gene_id: Hden_2160
symbol: Hden_2160
gene_biotype: protein_coding
description:
  PFAM: Carboxylesterase type B; KEGG: msl:Msil_3599 carboxylesterase type B; Belongs to the type-B carboxylesterase/lipase family.


ensembl_gene_id: Hden_2164
symbol: Hden_2164
gene_biotype: protein_coding
description:
  KEGG: msl:Msil_1853 transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain.


ensembl_gene_id: Hden_2166
symbol: Hden_2166
gene_biotype: protein_coding
description:
  PFAM: Mur ligase middle domain protein; KEGG: ppd:Ppro_2742 Mur ligase middle domain-containing protein.


ensembl_gene_id: Hden_2168
symbol: tgt
gene_biotype: protein_coding
description:
  Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...]


ensembl_gene_id: Hden_2169
symbol: queA
gene_biotype: protein_coding
description:
  S-adenosylmethionine/tRNA-ribosyltransferase- isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).


ensembl_gene_id: Hden_2171
symbol: Hden_2171
gene_biotype: protein_coding
description:
  Peptidyl-prolyl cis-trans isomerase cyclophilin type; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.


ensembl_gene_id: Hden_2173
symbol: Hden_2173
gene_biotype: protein_coding
description:
  PFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding; KEGG: psl:Psta_0102 methylated-DNA-(protein)-cysteine S-methyltransferase DNA binding protein.


ensembl_gene_id: Hden_2174
symbol: coaD
gene_biotype: protein_coding
description:
  Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.


ensembl_gene_id: Hden_2177
symbol: Hden_2177
gene_biotype: protein_coding
description:
  KEGG: mno:Mnod_6164 transcriptional regulator, Crp/Fnr family; PFAM: regulatory protein Crp; SMART: regulatory protein Crp.


ensembl_gene_id: Hden_2178
symbol: gyrA
gene_biotype: protein_coding
description:
  DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.


ensembl_gene_id: Hden_2181
symbol: Hden_2181
gene_biotype: protein_coding
description:
  KEGG: gdj:Gdia_1776 cation diffusion facilitator family transporter; TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein.


ensembl_gene_id: Hden_2182
symbol: Hden_2182
gene_biotype: protein_coding
description:
  Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.


ensembl_gene_id: Hden_2186
symbol: Hden_2186
gene_biotype: protein_coding
description:
  PFAM: glutathione-dependent formaldehyde-activating GFA; KEGG: msl:Msil_0879 glutathione-dependent formaldehyde-activating GFA.


ensembl_gene_id: Hden_2189
symbol: uvrA
gene_biotype: protein_coding
description:
  Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.


ensembl_gene_id: Hden_2190
symbol: Hden_2190
gene_biotype: protein_coding
description:
  PFAM: 3-demethylubiquinone-9 3-methyltransferase; KEGG: oca:OCAR_5407 3-demethylubiquinone-9 3-methyltransferase.


ensembl_gene_id: Hden_2194
symbol: Hden_2194
gene_biotype: protein_coding
description:
  KEGG: rso:RSp1381 PhnA protein alkylphosphonate uptake; TIGRFAM: alkylphosphonate utilization operon protein PhnA; PFAM: PhnA protein.


ensembl_gene_id: Hden_2198
symbol: Hden_2198
gene_biotype: protein_coding
description:
  Hypothetical protein; KEGG: svi:Svir_04970 IMP cyclohydrolase/phosphoribosylaminoimidazolecarboxamide formyltransferase.


ensembl_gene_id: Hden_2200
symbol: Hden_2200
gene_biotype: protein_coding
description:
  PFAM: short-chain dehydrogenase/reductase SDR; KEGG: bcg:BCG9842_B2506 short chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: Hden_2216
symbol: Hden_2216
gene_biotype: protein_coding
description:
  PFAM: DNA photolyase FAD-binding; DNA photolyase domain protein; KEGG: rce:RC1_2026 deoxyribodipyrimidine photolyase family protein.


ensembl_gene_id: Hden_2217
symbol: Hden_2217
gene_biotype: protein_coding
description:
  KEGG: bhy:BHWA1_02529 TPR domain-containing protein; PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide repeat.


ensembl_gene_id: Hden_2219
symbol: nnrD
gene_biotype: protein_coding
description:
  Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.  Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...]


ensembl_gene_id: Hden_2220
symbol: Hden_2220
gene_biotype: protein_coding
description:
  PFAM: nitrogen regulatory protein P-II; KEGG: xau:Xaut_3586 nitrogen regulatory protein P-II; Belongs to the P(II) protein family.


ensembl_gene_id: Hden_2221
symbol: Hden_2221
gene_biotype: protein_coding
description:
  KEGG: avi:Avi_2375 glutamine synthetase; TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp.


ensembl_gene_id: Hden_2223
symbol: Hden_2223
gene_biotype: protein_coding
description:
  PFAM: major facilitator superfamily MFS_1; KEGG: mea:Mex_1p4860 permease of major facilitator transporter (tat pathway signal).


ensembl_gene_id: Hden_2234
symbol: lipB
gene_biotype: protein_coding
description:
  Lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.


ensembl_gene_id: Hden_2236
symbol: Hden_2236
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: mag:amb4341 transcriptional regulator.


ensembl_gene_id: Hden_2237
symbol: Hden_2237
gene_biotype: protein_coding
description:
  Carbamoyl-phosphate synthase L chain ATP-binding protein; KEGG: bra:BRADO3249 putative acyl-CoA carboxylase biotin-carrying subunit; alpha chain; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; biotin carboxylase domain protein; Carbamoyl-phosphate synthetase large chain domain protein; biotin/lipoyl attachment domain-containing protein; SMART: biotin carboxylase domain protein.


ensembl_gene_id: Hden_2240
symbol: era
gene_biotype: protein_coding
description:
  GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.


ensembl_gene_id: Hden_2241
symbol: rnc
gene_biotype: protein_coding
description:
  Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.


ensembl_gene_id: Hden_2242
symbol: Hden_2242
gene_biotype: protein_coding
description:
  TIGRFAM: signal peptidase I; KEGG: xau:Xaut_3880 signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; Belongs to the peptidase S26 family.


ensembl_gene_id: Hden_2243
symbol: acpS
gene_biotype: protein_coding
description:
  Holo-acyl-carrier-protein synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.


ensembl_gene_id: Hden_2244
symbol: pdxJ
gene_biotype: protein_coding
description:
  Pyridoxal phosphate biosynthetic protein PdxJ; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.


ensembl_gene_id: Hden_2246
symbol: Hden_2246
gene_biotype: protein_coding
description:
  (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.


ensembl_gene_id: Hden_2247
symbol: rpoZ
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.


ensembl_gene_id: Hden_2249
symbol: Hden_2249
gene_biotype: protein_coding
description:
  PFAM: Uracil-DNA glycosylase superfamily; KEGG: pla:Plav_2864 uracil-DNA glycosylase superfamily protein.


ensembl_gene_id: Hden_2251
symbol: smpB
gene_biotype: protein_coding
description:
  SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]


ensembl_gene_id: Hden_2252
symbol: dapA
gene_biotype: protein_coding
description:
  Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).


ensembl_gene_id: Hden_2268
symbol: Hden_2268
gene_biotype: protein_coding
description:
  PFAM: secretion protein HlyD family protein; KEGG: spl:Spea_2191 secretion protein HlyD family protein.


ensembl_gene_id: Hden_2269
symbol: Hden_2269
gene_biotype: protein_coding
description:
  KEGG: spl:Spea_2190 EmrB/QacA family drug resistance transporter; TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1.


ensembl_gene_id: Hden_2270
symbol: Hden_2270
gene_biotype: protein_coding
description:
  KEGG: azc:AZC_0972 response regulator receiver; PFAM: response regulator receiver; SMART: response regulator receiver.


ensembl_gene_id: Hden_2271
symbol: Hden_2271
gene_biotype: protein_coding
description:
  KEGG: msl:Msil_0850 response regulator receiver protein; PFAM: response regulator receiver; SMART: response regulator receiver.


ensembl_gene_id: Hden_2273
symbol: Hden_2273
gene_biotype: protein_coding
description:
  Transcriptional regulator, Crp/Fnr family; KEGG: nwi:Nwi_2417 cyclic nucleotide-binding protein; PFAM: cyclic nucleotide-binding; regulatory protein Crp; SMART: cyclic nucleotide-binding; regulatory protein Crp.


ensembl_gene_id: Hden_2276
symbol: Hden_2276
gene_biotype: protein_coding
description:
  ybaK/ebsC protein; KEGG: mag:amb0011 hypothetical protein; TIGRFAM: ybaK/ebsC protein; PFAM: YbaK/prolyl-tRNA synthetase associated region; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.


ensembl_gene_id: Hden_2279
symbol: Hden_2279
gene_biotype: protein_coding
description:
  PFAM: AMP-dependent synthetase and ligase; KEGG: cce:Ccel_0875 coenzyme F390 synthetase-like protein.


ensembl_gene_id: Hden_2281
symbol: Hden_2281
gene_biotype: protein_coding
description:
  SMART: metal-dependent phosphohydrolase HD region; KEGG: tkm:TK90_2611 metal dependent phosphohydrolase.


ensembl_gene_id: Hden_2283
symbol: Hden_2283
gene_biotype: protein_coding
description:
  KEGG: rpa:RPA3082 cyclopropane-fatty-acyl-phospholipid synthase; PFAM: Cyclopropane-fatty-acyl-phospholipid synthase.


ensembl_gene_id: Hden_2286
symbol: Hden_2286
gene_biotype: protein_coding
description:
  KEGG: rpc:RPC_0729 extracellular solute-binding protein; PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3.


ensembl_gene_id: Hden_2296
symbol: pyrE
gene_biotype: protein_coding
description:
  Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).


ensembl_gene_id: Hden_2297
symbol: Hden_2297
gene_biotype: protein_coding
description:
  Carboxymethylenebutenolidase; KEGG: bbt:BBta_2303 putative carboxymethylenebutenolidase; PFAM: dienelactone hydrolase.


ensembl_gene_id: Hden_2298
symbol: pckA
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.


ensembl_gene_id: Hden_2299
symbol: Hden_2299
gene_biotype: protein_coding
description:
  KEGG: msl:Msil_0255 two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; transcriptional regulator domain protein.


ensembl_gene_id: Hden_2300
symbol: Hden_2300
gene_biotype: protein_coding
description:
  Integral membrane sensor signal transduction histidine kinase; KEGG: azc:AZC_4066 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein.


ensembl_gene_id: Hden_2302
symbol: Hden_2302
gene_biotype: protein_coding
description:
  PFAM: PTS system fructose subfamily IIA component; KEGG: xau:Xaut_2848 PTS system fructose subfamily IIA component.


ensembl_gene_id: Hden_2303
symbol: Hden_2303
gene_biotype: protein_coding
description:
  Phosphotransferase system, phosphocarrier protein HPr; KEGG: rru:Rru_A3446 HPrNtr; TIGRFAM: phosphocarrier, HPr family; PFAM: phosphoryl transfer system HPr.


ensembl_gene_id: Hden_2305
symbol: ahcY
gene_biotype: protein_coding
description:
  Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.


ensembl_gene_id: Hden_2306
symbol: Hden_2306
gene_biotype: protein_coding
description:
  KEGG: oca:OCAR_4487 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein.


ensembl_gene_id: Hden_2307
symbol: Hden_2307
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function UPF0079; aminoglycoside phosphotransferase; KEGG: rpt:Rpal_0081 protein of unknown function UPF0079.


ensembl_gene_id: Hden_2309
symbol: Hden_2309
gene_biotype: protein_coding
description:
  TIGRFAM: double-strand break repair protein AddB; KEGG: azl:AZL_027200 double-strand break repair protein.


ensembl_gene_id: Hden_2310
symbol: Hden_2310
gene_biotype: protein_coding
description:
  KEGG: pla:Plav_0138 double-strand break repair helicase AddA; TIGRFAM: double-strand break repair helicase AddA; PFAM: UvrD/REP helicase; Belongs to the helicase family. UvrD subfamily.


ensembl_gene_id: Hden_2311
symbol: Hden_2311
gene_biotype: protein_coding
description:
  Thioredoxin; KEGG: rak:A1C_00010 thioredoxin; TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; Belongs to the thioredoxin family.


ensembl_gene_id: Hden_2315
symbol: Hden_2315
gene_biotype: protein_coding
description:
  PFAM: Aldehyde Dehydrogenase; KEGG: sjp:SJA_C2-05820 putative aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: Hden_2316
symbol: Hden_2316
gene_biotype: protein_coding
description:
  TIGRFAM: FolC bifunctional protein; KEGG: pla:Plav_0140 FolC bifunctional protein; PFAM: Mur ligase middle domain protein; Belongs to the folylpolyglutamate synthase family.


ensembl_gene_id: Hden_2317
symbol: accD
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.


ensembl_gene_id: Hden_2318
symbol: trpA
gene_biotype: protein_coding
description:
  Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.


ensembl_gene_id: Hden_2319
symbol: trpB
gene_biotype: protein_coding
description:
  Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.


ensembl_gene_id: Hden_2320
symbol: trpF
gene_biotype: protein_coding
description:
  KEGG: bja:blr0744 N-(5'-phosphoribosyl)anthranilate isomerase; PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); Belongs to the TrpF family.


ensembl_gene_id: Hden_2323
symbol: ihfB
gene_biotype: protein_coding
description:
  Integration host factor, beta subunit; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.


ensembl_gene_id: Hden_2324
symbol: Hden_2324
gene_biotype: protein_coding
description:
  KEGG: mes:Meso_3671 signal peptide peptidase A; TIGRFAM: signal peptide peptidase SppA, 36K type; PFAM: peptidase S49.


ensembl_gene_id: Hden_2325
symbol: Hden_2325
gene_biotype: protein_coding
description:
  Ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.


ensembl_gene_id: Hden_2329
symbol: aroA
gene_biotype: protein_coding
description:
  3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.


ensembl_gene_id: Hden_2334
symbol: Hden_2334
gene_biotype: protein_coding
description:
  ABC transporter related protein; KEGG: oca:OCAR_6476 holdfast attachment protein C (protein HfaC); PFAM: ABC transporter related; SMART: AAA ATPase.


ensembl_gene_id: Hden_2336
symbol: Hden_2336
gene_biotype: protein_coding
description:
  PFAM: heat shock protein Hsp20; KEGG: bid:Bind_0512 heat shock protein HSP20; Belongs to the small heat shock protein (HSP20) family.


ensembl_gene_id: Hden_2339
symbol: Hden_2339
gene_biotype: protein_coding
description:
  Transcriptional regulator, ArsR family; KEGG: har:HEAR3303 ArsR regulator operon ArsI; PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR.


ensembl_gene_id: Hden_2340
symbol: Hden_2340
gene_biotype: protein_coding
description:
  KEGG: mag:amb1828 protein-tyrosine-phosphatase; PFAM: Protein-tyrosine phosphatase, low molecular weight; SMART: Protein-tyrosine phosphatase, low molecular weight.


ensembl_gene_id: Hden_2341
symbol: Hden_2341
gene_biotype: protein_coding
description:
  KEGG: oca:OCAR_4230 arsenical-resistance protein; TIGRFAM: arsenical-resistance protein; PFAM: Bile acid:sodium symporter.


ensembl_gene_id: Hden_2342
symbol: Hden_2342
gene_biotype: protein_coding
description:
  KEGG: mlo:mll2167 arsenate reductase; TIGRFAM: arsenate reductase; PFAM: arsenate reductase and related.


ensembl_gene_id: Hden_2343
symbol: Hden_2343
gene_biotype: protein_coding
description:
  KEGG: oca:OCAR_4229 arsenical resistance protein ArsH; TIGRFAM: arsenical resistance protein ArsH; PFAM: NADPH-dependent FMN reductase.


ensembl_gene_id: Hden_2345
symbol: Hden_2345
gene_biotype: protein_coding
description:
  Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: Hden_2346
symbol: panC
gene_biotype: protein_coding
description:
  Pantoate/beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.


ensembl_gene_id: Hden_2347
symbol: parE
gene_biotype: protein_coding
description:
  DNA topoisomerase IV, B subunit; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily.


ensembl_gene_id: Hden_2349
symbol: Hden_2349
gene_biotype: protein_coding
description:
  PFAM: major intrinsic protein; KEGG: spe:Spro_1009 aquaporin Z; Belongs to the MIP/aquaporin (TC 1.A.8) family.


ensembl_gene_id: Hden_2350
symbol: Hden_2350
gene_biotype: protein_coding
description:
  KEGG: mrd:Mrad2831_0999 DEAD/DEAH box helicase domain-containing protein; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; Belongs to the DEAD box helicase family.


ensembl_gene_id: Hden_2351
symbol: Hden_2351
gene_biotype: protein_coding
description:
  Hypothetical protein; KEGG: tgu:100190018 evectin-2 pleckstrin homology domain containing family B member 2-like.


ensembl_gene_id: Hden_2352
symbol: Hden_2352
gene_biotype: protein_coding
description:
  KEGG: azc:AZC_3609 HesB protein; TIGRFAM: iron-sulfur cluster assembly accessory protein; PFAM: HesB/YadR/YfhF-family protein; Belongs to the HesB/IscA family.


ensembl_gene_id: Hden_2353
symbol: Hden_2353
gene_biotype: protein_coding
description:
  KEGG: mpo:Mpop_4461 FeS assembly SUF system protein; TIGRFAM: FeS assembly SUF system protein; PFAM: protein of unknown function DUF59.


ensembl_gene_id: Hden_2354
symbol: Hden_2354
gene_biotype: protein_coding
description:
  Cysteine desulfurase, SufS subfamily; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.


ensembl_gene_id: Hden_2355
symbol: Hden_2355
gene_biotype: protein_coding
description:
  KEGG: nha:Nham_2326 FeS assembly protein SufD; TIGRFAM: FeS assembly protein SufD; PFAM: SufBD protein.


ensembl_gene_id: Hden_2356
symbol: Hden_2356
gene_biotype: protein_coding
description:
  TIGRFAM: FeS assembly ATPase SufC; PFAM: ABC transporter related; KEGG: pde:Pden_3966 FeS assembly ATPase SufC; SMART: AAA ATPase.


ensembl_gene_id: Hden_2358
symbol: Hden_2358
gene_biotype: protein_coding
description:
  FeS assembly protein SufB; KEGG: atc:AGR_C_3348 ABC transporter membrane protein XF1476; TIGRFAM: FeS assembly protein SufB; PFAM: SufBD protein.


ensembl_gene_id: Hden_2359
symbol: Hden_2359
gene_biotype: protein_coding
description:
  TIGRFAM: transcriptional regulator, Rrf2 family; KEGG: rce:RC1_1616 cysteine desulfurase; PFAM: aminotransferase class V; protein of unknown function UPF0074.


ensembl_gene_id: Hden_2361
symbol: anmK
gene_biotype: protein_coding
description:
  Protein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family.


ensembl_gene_id: Hden_2362
symbol: tyrS
gene_biotype: protein_coding
description:
  tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.


ensembl_gene_id: Hden_2364
symbol: Hden_2364
gene_biotype: protein_coding
description:
  PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; KEGG: sme:SMc00524 putative bacterioferritin comigratory protein.


ensembl_gene_id: Hden_2368
symbol: Hden_2368
gene_biotype: protein_coding
description:
  PFAM: multiple antibiotic resistance (MarC)-related protein; KEGG: tkm:TK90_2079 multiple antibiotic resistance (MarC)-related protein.


ensembl_gene_id: Hden_2369
symbol: Hden_2369
gene_biotype: protein_coding
description:
  PFAM: Usg family protein; KEGG: pzu:PHZ_c3229 usg protein, probable subunit of phosphoribosylanthranilate isomerase.


ensembl_gene_id: Hden_2370
symbol: Hden_2370
gene_biotype: protein_coding
description:
  KEGG: met:M446_6435 ECF subfamily RNA polymerase sigma-24 factor; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2.


ensembl_gene_id: Hden_2372
symbol: Hden_2372
gene_biotype: protein_coding
description:
  PFAM: blue (type 1) copper domain protein; KEGG: sil:SPO0256 plastocyanin/azurin family copper binding protein.


ensembl_gene_id: Hden_2373
symbol: Hden_2373
gene_biotype: protein_coding
description:
  KEGG: mno:Mnod_7690 signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation/phosphoacceptor; SMART: ATP-binding region ATPase domain protein.


ensembl_gene_id: Hden_2374
symbol: Hden_2374
gene_biotype: protein_coding
description:
  Hypothetical protein; KEGG: pml:ATP_00463 probable oligopeptide ABC transporter, substrate-binding protein.


ensembl_gene_id: Hden_2375
symbol: Hden_2375
gene_biotype: protein_coding
description:
  KEGG: bja:bsl4595 cold shock protein; PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein.


ensembl_gene_id: Hden_2377
symbol: Hden_2377
gene_biotype: protein_coding
description:
  KEGG: azc:AZC_3509 putative methanol dehydrogenase regulator; PFAM: ATPase associated with various cellular activities AAA_3; SMART: AAA ATPase.


ensembl_gene_id: Hden_2391
symbol: Hden_2391
gene_biotype: protein_coding
description:
  PFAM: Mg2 transporter protein CorA family protein; KEGG: rru:Rru_A1883 magnesium/cobalt transporter CorA.


ensembl_gene_id: Hden_2395
symbol: Hden_2395
gene_biotype: protein_coding
description:
  Helix-turn-helix domain protein; KEGG: bbt:BBta_0665 hypothetical protein; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein.


ensembl_gene_id: Hden_2404
symbol: Hden_2404
gene_biotype: protein_coding
description:
  Hypothetical protein; KEGG: spu:586898 similar to N-acetyltransferase ESCO1 (Establishment of cohesion 1 homolog 1).


ensembl_gene_id: Hden_2405
symbol: purA
gene_biotype: protein_coding
description:
  Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.


ensembl_gene_id: Hden_2407
symbol: Hden_2407
gene_biotype: protein_coding
description:
  TIGRFAM: phosphoserine aminotransferase; KEGG: bid:Bind_1270 phosphoserine aminotransferase; PFAM: aminotransferase class V.


ensembl_gene_id: Hden_2410
symbol: glmM
gene_biotype: protein_coding
description:
  Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.


ensembl_gene_id: Hden_2413
symbol: Hden_2413
gene_biotype: protein_coding
description:
  PFAM: amino acid permease-associated region; KEGG: rxy:Rxyl_1097 amino acid permease-associated region.


ensembl_gene_id: Hden_2414
symbol: Hden_2414
gene_biotype: protein_coding
description:
  PFAM: pyridoxamine 5'-phosphate oxidase-related FMN-binding; KEGG: bbt:BBta_7101 hypothetical protein.


ensembl_gene_id: Hden_2415
symbol: Hden_2415
gene_biotype: protein_coding
description:
  TIGRFAM: dihydropteroate synthase; KEGG: rsk:RSKD131_0172 dihydropteroate synthase; PFAM: dihydropteroate synthase DHPS.


ensembl_gene_id: Hden_2416
symbol: ftsH
gene_biotype: protein_coding
description:
  ATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family.  In the central section; belongs to the AAA ATPase family.


ensembl_gene_id: Hden_2417
symbol: tilS
gene_biotype: protein_coding
description:
  tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.


ensembl_gene_id: Hden_2418
symbol: cpoB
gene_biotype: protein_coding
description:
  Tol-pal system protein YbgF; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family.


ensembl_gene_id: Hden_2419
symbol: Hden_2419
gene_biotype: protein_coding
description:
  PFAM: OmpA/MotB domain protein; KEGG: bra:BRADO1176 outer membrane lipoprotein omp16 precursor (peptidoglycan-associated lipoprotein).


ensembl_gene_id: Hden_2420
symbol: pal
gene_biotype: protein_coding
description:
  Peptidoglycan-associated lipoprotein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: Hden_2423
symbol: tolB
gene_biotype: protein_coding
description:
  Tol-Pal system beta propeller repeat protein TolB; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: Hden_2425
symbol: Hden_2425
gene_biotype: protein_coding
description:
  Protein TolR; KEGG: azc:AZC_0522 biopolymer transport protein; TIGRFAM: protein TolR; PFAM: Biopolymer transport protein ExbD/TolR.


ensembl_gene_id: Hden_2426
symbol: tolQ
gene_biotype: protein_coding
description:
  Protein TolQ; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: Hden_2430
symbol: Hden_2430
gene_biotype: protein_coding
description:
  PFAM: amino acid permease-associated region; KEGG: smd:Smed_3297 amino acid permease-associated region.


ensembl_gene_id: Hden_2433
symbol: Hden_2433
gene_biotype: protein_coding
description:
  KEGG: rpc:RPC_1924 4-hydroxybenzoyl-CoA thioesterase; TIGRFAM: tol-pal system-associated acyl-CoA thioesterase; PFAM: thioesterase superfamily protein.


ensembl_gene_id: Hden_2435
symbol: ruvB
gene_biotype: protein_coding
description:
  Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.


ensembl_gene_id: Hden_2437
symbol: ruvA
gene_biotype: protein_coding
description:
  Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.


ensembl_gene_id: Hden_2438
symbol: ruvC
gene_biotype: protein_coding
description:
  Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.


ensembl_gene_id: Hden_2443
symbol: Hden_2443
gene_biotype: protein_coding
description:
  KEGG: oca:OCAR_7307 5-formyltetrahydrofolate cyclo-ligase; TIGRFAM: 5-formyltetrahydrofolate cyclo-ligase; PFAM: 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.


ensembl_gene_id: Hden_2444
symbol: Hden_2444
gene_biotype: protein_coding
description:
  Protein of unknown function DUF710; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.


ensembl_gene_id: Hden_2446
symbol: Hden_2446
gene_biotype: protein_coding
description:
  SMART: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; KEGG: xau:Xaut_3075 glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.


ensembl_gene_id: Hden_2448
symbol: Hden_2448
gene_biotype: protein_coding
description:
  PFAM: ErfK/YbiS/YcfS/YnhG family protein; Peptidoglycan-binding domain 1 protein; KEGG: azc:AZC_0439 hypothetical protein.


ensembl_gene_id: Hden_2450
symbol: Hden_2450
gene_biotype: protein_coding
description:
  KEGG: oca:OCAR_7315 Sel1; PFAM: Sel1 domain protein repeat-containing protein; SMART: Sel1 domain protein repeat-containing protein.


ensembl_gene_id: Hden_2454
symbol: Hden_2454
gene_biotype: protein_coding
description:
  TIGRFAM: lipid A ABC exporter family, fused ATPase and inner membrane subunits; PFAM: ABC transporter related; ABC transporter transmembrane region; KEGG: rhi:NGR_c28180 putative ABC transporter, ATP-binding protein, ATPase; SMART: AAA ATPase.


ensembl_gene_id: Hden_2455
symbol: Hden_2455
gene_biotype: protein_coding
description:
  KEGG: mes:Meso_3190 50S ribosomal protein L31; TIGRFAM: ribosomal protein L31; PFAM: ribosomal protein L31; Belongs to the bacterial ribosomal protein bL31 family.


ensembl_gene_id: Hden_2459
symbol: Hden_2459
gene_biotype: protein_coding
description:
  NAD(P)H quinone oxidoreductase, PIG3 family; KEGG: rru:Rru_A1056 zinc-containing alcohol dehydrogenase superfamily protein; TIGRFAM: NAD(P)H quinone oxidoreductase, PIG3 family; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein.


ensembl_gene_id: Hden_2460
symbol: Hden_2460
gene_biotype: protein_coding
description:
  KEGG: met:M446_2225 HAD family hydrolase; TIGRFAM: HAD-superfamily hydrolase, subfamily IIA; HAD-superfamily subfamily IIA hydrolase like protein; PFAM: Haloacid dehalogenase domain protein hydrolase.


ensembl_gene_id: Hden_2461
symbol: Hden_2461
gene_biotype: protein_coding
description:
  KEGG: rpt:Rpal_1371 diguanylate phosphodiesterase; PFAM: EAL domain protein; SMART: EAL domain protein.


ensembl_gene_id: Hden_2463
symbol: Hden_2463
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: azl:AZL_a00120 transcriptional regulator.


ensembl_gene_id: Hden_2464
symbol: Hden_2464
gene_biotype: protein_coding
description:
  PFAM: NADH dehydrogenase (ubiquinone) 24 kDa subunit; KEGG: reh:H16_A0640 NAD-dependent formate dehydrogenase gamma subunit.


ensembl_gene_id: Hden_2465
symbol: Hden_2465
gene_biotype: protein_coding
description:
  NADH dehydrogenase (quinone); KEGG: azl:AZL_a00160 formate dehydrogenase, beta subunit; PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; Soluble ligand binding domain.


ensembl_gene_id: Hden_2466
symbol: Hden_2466
gene_biotype: protein_coding
description:
  Manually curated; TIGRFAM: formate dehydrogenase, alpha subunit; KEGG: azl:AZL_a00170 formate dehydrogenase, alpha subunit; PFAM: molybdopterin oxidoreductase; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; ferredoxin; 4Fe-4S ferredoxin iron-sulfur binding domain protein; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region.


ensembl_gene_id: Hden_2467
symbol: fdhD
gene_biotype: protein_coding
description:
  Formate dehydrogenase family accessory protein FdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.


ensembl_gene_id: Hden_2469
symbol: Hden_2469
gene_biotype: protein_coding
description:
  TIGRFAM: small GTP-binding protein; PFAM: elongation factor G domain IV; elongation factor Tu domain 2 protein; protein synthesis factor GTP-binding; elongation factor G domain protein; KEGG: rpc:RPC_4119 elongation factor G; SMART: elongation factor G domain IV; elongation factor G domain protein.


ensembl_gene_id: Hden_2474
symbol: Hden_2474
gene_biotype: protein_coding
description:
  PFAM: short-chain dehydrogenase/reductase SDR; KEGG: gvi:glr0293 carbonyl reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: Hden_2476
symbol: uvrB
gene_biotype: protein_coding
description:
  Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]


ensembl_gene_id: Hden_2477
symbol: Hden_2477
gene_biotype: protein_coding
description:
  KEGG: mno:Mnod_1815 intracellular protease, PfpI family; TIGRFAM: intracellular protease, PfpI family; PFAM: ThiJ/PfpI domain protein.


ensembl_gene_id: Hden_2478
symbol: Hden_2478
gene_biotype: protein_coding
description:
  Hypothetical protein; KEGG: tmz:Tmz1t_3431 UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate/D-alanyl-D -alanyl ligase.


ensembl_gene_id: Hden_2486
symbol: Hden_2486
gene_biotype: protein_coding
description:
  Two component transcriptional regulator, winged helix family; KEGG: mlo:mll2816 two-component transcriptional regulator; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; transcriptional regulator domain protein.


ensembl_gene_id: Hden_2490
symbol: mnmA
gene_biotype: protein_coding
description:
  tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.


ensembl_gene_id: Hden_2492
symbol: Hden_2492
gene_biotype: protein_coding
description:
  PFAM: Class I peptide chain release factor; KEGG: rce:RC1_1710 peptidyl-tRNA hydrolase domain, putative.


ensembl_gene_id: Hden_2496
symbol: ilvE
gene_biotype: protein_coding
description:
  Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: Hden_2497
symbol: Hden_2497
gene_biotype: protein_coding
description:
  Transcriptional regulator, MarR family; KEGG: azc:AZC_3973 regulatory protein; PFAM: regulatory protein MarR; SMART: regulatory protein MarR.


ensembl_gene_id: Hden_2498
symbol: Hden_2498
gene_biotype: protein_coding
description:
  Two component transcriptional regulator, winged helix family; KEGG: mes:Meso_2142 two component transcriptional regulator; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; transcriptional regulator domain protein.


ensembl_gene_id: Hden_2499
symbol: Hden_2499
gene_biotype: protein_coding
description:
  KEGG: rpe:RPE_1426 periplasmic sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein.


ensembl_gene_id: Hden_2500
symbol: proC
gene_biotype: protein_coding
description:
  Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.


ensembl_gene_id: Hden_2504
symbol: lgt
gene_biotype: protein_coding
description:
  Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.


ensembl_gene_id: Hden_2506
symbol: Hden_2506
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF152; KEGG: pzu:PHZ_c2860 hypothetical protein; Belongs to the multicopper oxidase YfiH/RL5 family.


ensembl_gene_id: Hden_2508
symbol: prs
gene_biotype: protein_coding
description:
  Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.


ensembl_gene_id: Hden_2510
symbol: Hden_2510
gene_biotype: protein_coding
description:
  PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: bid:Bind_1144 alcohol dehydrogenase.


ensembl_gene_id: Hden_2512
symbol: rplY
gene_biotype: protein_coding
description:
  Ribosomal 5S rRNA E-loop binding protein Ctc/L25/TL5; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.


ensembl_gene_id: Hden_2513
symbol: pth
gene_biotype: protein_coding
description:
  peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.


ensembl_gene_id: Hden_2515
symbol: ychF
gene_biotype: protein_coding
description:
  GTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.


ensembl_gene_id: Hden_2519
symbol: Hden_2519
gene_biotype: protein_coding
description:
  PFAM: class II aldolase/adducin family protein; KEGG: pla:Plav_2248 class II aldolase/adducin family protein.


ensembl_gene_id: Hden_2520
symbol: mtnA
gene_biotype: protein_coding
description:
  Translation initiation factor, aIF-2BI family; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).


ensembl_gene_id: Hden_2523
symbol: apt
gene_biotype: protein_coding
description:
  Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.


ensembl_gene_id: Hden_2525
symbol: mtnP
gene_biotype: protein_coding
description:
  Methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.


ensembl_gene_id: Hden_2527
symbol: Hden_2527
gene_biotype: protein_coding
description:
  Cytochrome b/b6 domain protein; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.


ensembl_gene_id: Hden_2528
symbol: Hden_2528
gene_biotype: protein_coding
description:
  Ubiquinol-cytochrome c reductase, iron-sulfur subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.


ensembl_gene_id: Hden_2529
symbol: trmL
gene_biotype: protein_coding
description:
  tRNA/rRNA methyltransferase (SpoU); Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.


ensembl_gene_id: Hden_2531
symbol: Hden_2531
gene_biotype: protein_coding
description:
  ABC transporter related protein; KEGG: pap:PSPA7_1898 putative ATP-binding/permease fusion ABC transporter; PFAM: ABC transporter related; SMART: AAA ATPase.


ensembl_gene_id: Hden_2532
symbol: hemF
gene_biotype: protein_coding
description:
  Coproporphyrinogen oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX.


ensembl_gene_id: Hden_2534
symbol: Hden_2534
gene_biotype: protein_coding
description:
  PFAM: NADH:flavin oxidoreductase/NADH oxidase; KEGG: bph:Bphy_4808 NADH:flavin oxidoreductase/NADH oxidase.


ensembl_gene_id: Hden_2538
symbol: Hden_2538
gene_biotype: protein_coding
description:
  PFAM: Polynucleotide adenylyltransferase region; KEGG: rpb:RPB_1196 polynucleotide adenylyltransferase region; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.


ensembl_gene_id: Hden_2546
symbol: groL
gene_biotype: protein_coding
description:
  Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.


ensembl_gene_id: Hden_2547
symbol: groS
gene_biotype: protein_coding
description:
  Chaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.


ensembl_gene_id: Hden_2548
symbol: Hden_2548
gene_biotype: protein_coding
description:
  KEGG: rsq:Rsph17025_4162 hypothetical protein; PFAM: histone family protein nucleoid-structuring protein H-NS; SMART: histone family protein nucleoid-structuring protein H-NS.


ensembl_gene_id: Hden_2549
symbol: Hden_2549
gene_biotype: protein_coding
description:
  Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.


ensembl_gene_id: Hden_2550
symbol: Hden_2550
gene_biotype: protein_coding
description:
  KEGG: jan:Jann_0922 cyclic nucleotide-binding domain-containing protein; PFAM: Patatin; cyclic nucleotide-binding; SMART: cyclic nucleotide-binding.


ensembl_gene_id: Hden_2553
symbol: Hden_2553
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF853 NPT hydrolase putative; KEGG: mpo:Mpop_4924 protein of unknown function DUF853 NPT hydrolase putative.


ensembl_gene_id: Hden_2560
symbol: Hden_2560
gene_biotype: protein_coding
description:
  TIGRFAM: methylmalonyl-CoA mutase, large subunit; KEGG: mno:Mnod_4573 methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase; cobalamin B12-binding domain protein.


ensembl_gene_id: Hden_2561
symbol: Hden_2561
gene_biotype: protein_coding
description:
  Manually curated; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; KEGG: pla:Plav_2485 DEAD/DEAH box helicase domain-containing protein; SMART: DEAD-like helicase; helicase domain protein; Belongs to the DEAD box helicase family.


ensembl_gene_id: Hden_2563
symbol: Hden_2563
gene_biotype: protein_coding
description:
  KEGG: rpt:Rpal_4151 proline iminopeptidase; TIGRFAM: proline iminopeptidase; PFAM: alpha/beta hydrolase fold; Belongs to the peptidase S33 family.


ensembl_gene_id: Hden_2567
symbol: Hden_2567
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF900 hydrolase family protein; KEGG: pph:Ppha_1468 protein of unknown function DUF900 hydrolase family protein.


ensembl_gene_id: Hden_2568
symbol: Hden_2568
gene_biotype: protein_coding
description:
  KEGG: bbt:BBta_3019 arginine/ornithine transport system ATPase; TIGRFAM: LAO/AO transport system ATPase; PFAM: ArgK protein.


ensembl_gene_id: Hden_2569
symbol: Hden_2569
gene_biotype: protein_coding
description:
  PFAM: peptidase C15 pyroglutamyl peptidase I; KEGG: xau:Xaut_2489 peptidase C15 pyroglutamyl peptidase I.


ensembl_gene_id: Hden_2571
symbol: Hden_2571
gene_biotype: protein_coding
description:
  TIGRFAM: ATP-dependent DNA helicase RecQ; ATP-dependent DNA helicase, RecQ family; PFAM: RQC domain; DEAD/DEAH box helicase domain protein; helicase domain protein; HRDC domain protein; KEGG: tgr:Tgr7_1931 ATP-dependent DNA helicase RecQ; SMART: DEAD-like helicase; helicase domain protein; HRDC domain protein.


ensembl_gene_id: Hden_2573
symbol: Hden_2573
gene_biotype: protein_coding
description:
  ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.


ensembl_gene_id: Hden_2574
symbol: Hden_2574
gene_biotype: protein_coding
description:
  PFAM: tRNA synthetase class II (G H P and S); KEGG: pla:Plav_0599 ATP phosphoribosyltransferase regulatory subunit.


ensembl_gene_id: Hden_2575
symbol: hisS
gene_biotype: protein_coding
description:
  TIGRFAM: histidyl-tRNA synthetase; KEGG: bra:BRADO6038 histidyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); Anticodon-binding domain protein.


ensembl_gene_id: Hden_2577
symbol: cobS
gene_biotype: protein_coding
description:
  Cobalamin 5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.


ensembl_gene_id: Hden_2578
symbol: Hden_2578
gene_biotype: protein_coding
description:
  Nicotinate-nucleotide/dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).


ensembl_gene_id: Hden_2579
symbol: Hden_2579
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: met:M446_1761 hypothetical protein.


ensembl_gene_id: Hden_2581
symbol: Hden_2581
gene_biotype: protein_coding
description:
  D-lactate dehydrogenase (cytochrome); KEGG: mno:Mnod_4582 FAD linked oxidase domain protein; PFAM: FAD linked oxidase domain protein.


ensembl_gene_id: Hden_2582
symbol: Hden_2582
gene_biotype: protein_coding
description:
  Glutamate/cysteine ligase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.


ensembl_gene_id: Hden_2583
symbol: Hden_2583
gene_biotype: protein_coding
description:
  Protein of unknown function DUF558; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.


ensembl_gene_id: Hden_2584
symbol: ubiA
gene_biotype: protein_coding
description:
  4-hydroxybenzoate polyprenyl transferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.


ensembl_gene_id: Hden_2586
symbol: Hden_2586
gene_biotype: protein_coding
description:
  Protein tyrosine/serine phosphatase; PFAM: protein of unknown function DUF442; KEGG: met:M446_2662 protein tyrosine/serine phosphatase.


ensembl_gene_id: Hden_2587
symbol: Hden_2587
gene_biotype: protein_coding
description:
  PFAM: Three-deoxy-D-manno-octulosonic-acid transferase domain protein; glycosyl transferase group 1; protein of unknown function DUF374; KEGG: bra:BRADO6096 3-deoxy-D-manno-octulosonic-acid transferase (KDO transferase).


ensembl_gene_id: Hden_2588
symbol: lpxK
gene_biotype: protein_coding
description:
  Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).


ensembl_gene_id: Hden_2590
symbol: xseA
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease VII, large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family.


ensembl_gene_id: Hden_2591
symbol: purD
gene_biotype: protein_coding
description:
  TIGRFAM: phosphoribosylamine/glycine ligase; KEGG: rpe:RPE_4612 phosphoribosylamine--glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; Belongs to the GARS family.


ensembl_gene_id: Hden_2593
symbol: tadA
gene_biotype: protein_coding
description:
  CMP/dCMP deaminase zinc-binding protein; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.


ensembl_gene_id: Hden_2594
symbol: Hden_2594
gene_biotype: protein_coding
description:
  KEGG: rpt:Rpal_1356 RNA-binding S4 domain protein; PFAM: RNA-binding S4 domain protein; pseudouridine synthase; SMART: RNA-binding S4 domain protein; Belongs to the pseudouridine synthase RsuA family.


ensembl_gene_id: Hden_2595
symbol: Hden_2595
gene_biotype: protein_coding
description:
  Methyltransferase; KEGG: bra:BRADO6080 putative methyltransferase; TIGRFAM: methyltransferase; PFAM: Protein of unknown function methylase putative.


ensembl_gene_id: Hden_2598
symbol: Hden_2598
gene_biotype: protein_coding
description:
  KEGG: xom:XOO_3698 glucose-galactose transporter; TIGRFAM: glucose/galactose transporter; PFAM: major facilitator superfamily MFS_1.


ensembl_gene_id: Hden_2600
symbol: Hden_2600
gene_biotype: protein_coding
description:
  Bacterioferritin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family.


ensembl_gene_id: Hden_2601
symbol: mutL
gene_biotype: protein_coding
description:
  DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.


ensembl_gene_id: Hden_2604
symbol: Hden_2604
gene_biotype: protein_coding
description:
  PFAM: peptidase M16 domain protein; KEGG: azc:AZC_4242 putative protease precursor; Belongs to the peptidase M16 family.


ensembl_gene_id: Hden_2606
symbol: lspA
gene_biotype: protein_coding
description:
  Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.


ensembl_gene_id: Hden_2607
symbol: ileS
gene_biotype: protein_coding
description:
  isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).


ensembl_gene_id: Hden_2609
symbol: Hden_2609
gene_biotype: protein_coding
description:
  TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; Riboflavin kinase; KEGG: rpe:RPE_1410 riboflavin biosynthesis protein RibF; SMART: Riboflavin kinase; Belongs to the ribF family.


ensembl_gene_id: Hden_2612
symbol: Hden_2612
gene_biotype: protein_coding
description:
  PFAM: sulphate transporter; Sulfate transporter/antisigma-factor antagonist STAS; KEGG: mno:Mnod_1556 sulphate transporter.


ensembl_gene_id: Hden_2615
symbol: Hden_2615
gene_biotype: protein_coding
description:
  Hypothetical protein; KEGG: ppd:Ppro_1279 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein.


ensembl_gene_id: Hden_2616
symbol: Hden_2616
gene_biotype: protein_coding
description:
  Cobalamin synthesis protein P47K; KEGG: mdi:METDI3470 putative regulatory protein (nitrile hydratase activator like), putative GTPase, putative cobalamin biosynthesis protein (CobW homolog); PFAM: cobalamin synthesis protein P47K; cobalamin synthesis CobW domain protein; SMART: cobalamin synthesis CobW domain protein.


ensembl_gene_id: Hden_2618
symbol: Hden_2618
gene_biotype: protein_coding
description:
  PFAM: Activator of Hsp90 ATPase 1 family protein; KEGG: mes:Meso_2192 activator of HSP90 ATPase-like protein.


ensembl_gene_id: Hden_2619
symbol: Hden_2619
gene_biotype: protein_coding
description:
  KEGG: oca:OCAR_5411 transcriptional regulator, ArsR family; PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR.


ensembl_gene_id: Hden_2622
symbol: Hden_2622
gene_biotype: protein_coding
description:
  SMART: beta-lactamase domain protein; KEGG: acr:Acry_1612 exonuclease of the beta-lactamase fold involved in RNA processing-like protein.


ensembl_gene_id: Hden_2623
symbol: Hden_2623
gene_biotype: protein_coding
description:
  PFAM: ATP dependent DNA ligase; ATP dependent DNA ligase domain protein; KEGG: mea:Mex_1p3448 putative ATP-dependent DNA ligase.


ensembl_gene_id: Hden_2624
symbol: purE
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).


ensembl_gene_id: Hden_2625
symbol: purK
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).


ensembl_gene_id: Hden_2626
symbol: rpsU
gene_biotype: protein_coding
description:
  KEGG: rpb:RPB_1445 30S ribosomal protein S21; TIGRFAM: ribosomal protein S21; PFAM: ribosomal protein S21; Belongs to the bacterial ribosomal protein bS21 family.


ensembl_gene_id: Hden_2629
symbol: Hden_2629
gene_biotype: protein_coding
description:
  NAD(P)(+) transhydrogenase (AB-specific); The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.


ensembl_gene_id: Hden_2634
symbol: kup
gene_biotype: protein_coding
description:
  Potassium transporter; Transport of potassium into the cell; Belongs to the HAK/KUP transporter (TC 2.A.72) family.


ensembl_gene_id: Hden_2635
symbol: Hden_2635
gene_biotype: protein_coding
description:
  KEGG: mes:Meso_2730 PepF/M3 family oligoendopeptidase; TIGRFAM: oligoendopeptidase, pepF/M3 family; PFAM: peptidase M3A and M3B thimet/oligopeptidase F; Oligopeptidase F.


ensembl_gene_id: Hden_2636
symbol: Hden_2636
gene_biotype: protein_coding
description:
  KEGG: pla:Plav_2050 two component, sigma54 specific, Fis family transcriptional regulator; PFAM: sigma-54 factor interaction domain-containing protein; response regulator receiver; helix-turn-helix Fis-type; SMART: response regulator receiver; AAA ATPase.


ensembl_gene_id: Hden_2639
symbol: Hden_2639
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: oca:OCAR_4501 hydrogen peroxide-inducible genes activator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Hden_2640
symbol: Hden_2640
gene_biotype: protein_coding
description:
  PFAM: Protein of unknown function DUF2312; KEGG: rlt:Rleg2_3293 hypothetical protein; Belongs to the UPF0335 family.


ensembl_gene_id: Hden_2644
symbol: Hden_2644
gene_biotype: protein_coding
description:
  TIGRFAM: pyruvate kinase; KEGG: smd:Smed_2676 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family.


ensembl_gene_id: Hden_2645
symbol: Hden_2645
gene_biotype: protein_coding
description:
  KEGG: nwi:Nwi_0984 TPR repeat-containing protein; PFAM: Tetratricopeptide TPR_2 repeat protein; TPR repeat-containing protein; SMART: Tetratricopeptide repeat.


ensembl_gene_id: Hden_2646
symbol: rpmJ
gene_biotype: protein_coding
description:
  KEGG: nwi:Nwi_0983 50S ribosomal protein L36; manually curated; TIGRFAM: ribosomal protein L36; Belongs to the bacterial ribosomal protein bL36 family.


ensembl_gene_id: Hden_2647
symbol: Hden_2647
gene_biotype: protein_coding
description:
  Manually curated; PFAM: response regulator receiver; KEGG: mes:Meso_2750 response regulator receiver protein; SMART: response regulator receiver.


ensembl_gene_id: Hden_2649
symbol: Hden_2649
gene_biotype: protein_coding
description:
  KEGG: mno:Mnod_1726 histidinol-phosphate phosphatase; TIGRFAM: histidinol-phosphate phosphatase; PFAM: inositol monophosphatase.


ensembl_gene_id: Hden_2651
symbol: Hden_2651
gene_biotype: protein_coding
description:
  PFAM: heat shock protein Hsp20; KEGG: azc:AZC_4265 heat shock protein; Belongs to the small heat shock protein (HSP20) family.


ensembl_gene_id: Hden_2652
symbol: Hden_2652
gene_biotype: protein_coding
description:
  KEGG: bid:Bind_3031 glutamate synthase (ferredoxin); PFAM: glutamate synthase; ferredoxin-dependent glutamate synthase; glutamate synthase alpha subunit domain protein; glutamine amidotransferase class-II.


ensembl_gene_id: Hden_2653
symbol: Hden_2653
gene_biotype: protein_coding
description:
  KEGG: bbt:BBta_1370 glutamate synthase subunit beta; TIGRFAM: glutamate synthase, NADH/NADPH, small subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase.


ensembl_gene_id: Hden_2654
symbol: Hden_2654
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF6 transmembrane; KEGG: cti:RALTA_B0369 putative transmembrane protein.


ensembl_gene_id: Hden_2656
symbol: Hden_2656
gene_biotype: protein_coding
description:
  KEGG: rpe:RPE_2047 lytic murein transglycosylase; TIGRFAM: lytic murein transglycosylase; PFAM: Peptidoglycan-binding domain 1 protein.


ensembl_gene_id: Hden_2657
symbol: Hden_2657
gene_biotype: protein_coding
description:
  KEGG: xau:Xaut_0389 UTP-glucose-1-phosphate uridylyltransferase; TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase.


ensembl_gene_id: Hden_2659
symbol: Hden_2659
gene_biotype: protein_coding
description:
  KpsF/GutQ family protein; SMART: CBS domain containing protein; TIGRFAM: KpsF/GutQ family protein; KEGG: oan:Oant_4269 KpsF/GutQ family protein; PFAM: sugar isomerase (SIS); CBS domain containing protein; Belongs to the SIS family. GutQ/KpsF subfamily.


ensembl_gene_id: Hden_2660
symbol: hemH
gene_biotype: protein_coding
description:
  Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.


ensembl_gene_id: Hden_2661
symbol: Hden_2661
gene_biotype: protein_coding
description:
  KEGG: csa:Csal_2889 hypothetical protein; PFAM: CHAD domain containing protein; SMART: CHAD domain containing protein.


ensembl_gene_id: Hden_2662
symbol: thiE
gene_biotype: protein_coding
description:
  Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.


ensembl_gene_id: Hden_2665
symbol: Hden_2665
gene_biotype: protein_coding
description:
  AMP-dependent synthetase and ligase; KEGG: bja:bll2324 acylglycerophosphoethanolamine acyltransferase; PFAM: AMP-dependent synthetase and ligase; phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase.


ensembl_gene_id: Hden_2667
symbol: Hden_2667
gene_biotype: protein_coding
description:
  Gamma-glutamyltransferase; KEGG: bpt:Bpet0836 hypothetical protein; TIGRFAM: gamma-glutamyltransferase; PFAM: gamma-glutamyltranspeptidase.


ensembl_gene_id: Hden_2670
symbol: lipA
gene_biotype: protein_coding
description:
  Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.


ensembl_gene_id: Hden_2671
symbol: Hden_2671
gene_biotype: protein_coding
description:
  TIGRFAM: hydroxypyruvate isomerase; KEGG: bja:blr3167 putative hydroxypyruvate isomerase protein; PFAM: Xylose isomerase domain protein TIM barrel; Belongs to the hyi family.


ensembl_gene_id: Hden_2672
symbol: Hden_2672
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: nmu:Nmul_A1739 transcriptional regulator CysB-like protein.


ensembl_gene_id: Hden_2673
symbol: cysA
gene_biotype: protein_coding
description:
  Sulfate ABC transporter, ATPase subunit; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system.


ensembl_gene_id: Hden_2674
symbol: Hden_2674
gene_biotype: protein_coding
description:
  KEGG: tmz:Tmz1t_0623 sulfate ABC transporter, inner membrane subunit CysW; TIGRFAM: sulfate ABC transporter, inner membrane subunit CysW; sulfate ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component.


ensembl_gene_id: Hden_2675
symbol: Hden_2675
gene_biotype: protein_coding
description:
  Sulfate ABC transporter, inner membrane subunit CysT; Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: Hden_2676
symbol: Hden_2676
gene_biotype: protein_coding
description:
  KEGG: nwi:Nwi_0662 XRE family transcriptional regulator; PFAM: helix-turn-helix domain protein; Cupin 2 conserved barrel domain protein; SMART: helix-turn-helix domain protein.


ensembl_gene_id: Hden_2678
symbol: Hden_2678
gene_biotype: protein_coding
description:
  Protein of unknown function DUF1234; KEGG: azo:azo2398 hypothetical protein; manually curated; PFAM: protein of unknown function DUF1234.


ensembl_gene_id: Hden_2679
symbol: Hden_2679
gene_biotype: protein_coding
description:
  KEGG: azo:azo2363 putative periplasmic sulfate-binding protein; TIGRFAM: sulfate ABC transporter, periplasmic sulfate-binding protein; PFAM: extracellular solute-binding protein family 1.


ensembl_gene_id: Hden_2681
symbol: Hden_2681
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF214; KEGG: rde:RD1_1737 peptide ABC transporter, permease component, putative.


ensembl_gene_id: Hden_2682
symbol: Hden_2682
gene_biotype: protein_coding
description:
  KEGG: pen:PSEEN0581 ABC transporter, ATP binding component; PFAM: ABC transporter related; SMART: AAA ATPase.


ensembl_gene_id: Hden_2685
symbol: Hden_2685
gene_biotype: protein_coding
description:
  KEGG: mpo:Mpop_0172 signal transduction histidine kinase; PFAM: HWE histidine kinase; PAS fold-3 domain protein; SMART: PAC repeat-containing protein.


ensembl_gene_id: Hden_2687
symbol: Hden_2687
gene_biotype: protein_coding
description:
  RNA polymerase, sigma-24 subunit, ECF subfamily; KEGG: rpe:RPE_1751 two-component response regulator; PFAM: response regulator receiver; Sigma-70 region 4 type 2; SMART: response regulator receiver.


ensembl_gene_id: Hden_2688
symbol: Hden_2688
gene_biotype: protein_coding
description:
  KEGG: bid:Bind_3241 ECF subfamily RNA polymerase sigma-24 factor; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2.


ensembl_gene_id: Hden_2690
symbol: cobB
gene_biotype: protein_coding
description:
  Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.


ensembl_gene_id: Hden_2691
symbol: Hden_2691
gene_biotype: protein_coding
description:
  TIGRFAM: precorrin-4 C11-methyltransferase; KEGG: bbt:BBta_3152 precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family.


ensembl_gene_id: Hden_2693
symbol: Hden_2693
gene_biotype: protein_coding
description:
  TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; KEGG: met:M446_2444 precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase.


ensembl_gene_id: Hden_2694
symbol: Hden_2694
gene_biotype: protein_coding
description:
  TIGRFAM: precorrin-6x reductase; KEGG: rpc:RPC_1885 cobalt-precorrin-6x reductase; PFAM: Precorrin-6x reductase CbiJ/CobK.


ensembl_gene_id: Hden_2695
symbol: Hden_2695
gene_biotype: protein_coding
description:
  KEGG: bid:Bind_3511 precorrin-3B C17-methyltransferase; TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase.


ensembl_gene_id: Hden_2696
symbol: Hden_2696
gene_biotype: protein_coding
description:
  KEGG: gbe:GbCGDNIH1_0661 precorrin-2 C20-methyltransferase; TIGRFAM: precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family.


ensembl_gene_id: Hden_2698
symbol: Hden_2698
gene_biotype: protein_coding
description:
  KEGG: bid:Bind_3508 precorrin-3B synthase; TIGRFAM: precorrin-3B synthase; PFAM: nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein.


ensembl_gene_id: Hden_2699
symbol: Hden_2699
gene_biotype: protein_coding
description:
  TIGRFAM: cobaltochelatase, CobN subunit; KEGG: rpc:RPC_1889 cobaltochelatase subunit CobN; PFAM: CobN/magnesium chelatase.


ensembl_gene_id: Hden_2700
symbol: Hden_2700
gene_biotype: protein_coding
description:
  TIGRFAM: cobalamin biosynthesis protein CobW; PFAM: cobalamin synthesis protein P47K; cobalamin synthesis CobW domain protein; KEGG: bra:BRADO4908 putative cobalamin synthesis protein CobW; SMART: cobalamin synthesis CobW domain protein.


ensembl_gene_id: Hden_2701
symbol: Hden_2701
gene_biotype: protein_coding
description:
  Adenosylcobinamide-phosphate guanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.


ensembl_gene_id: Hden_2702
symbol: Hden_2702
gene_biotype: protein_coding
description:
  cob(I)alamin adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.


ensembl_gene_id: Hden_2703
symbol: cobQ
gene_biotype: protein_coding
description:
  Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.


ensembl_gene_id: Hden_2704
symbol: cobD
gene_biotype: protein_coding
description:
  Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.


ensembl_gene_id: Hden_2705
symbol: Hden_2705
gene_biotype: protein_coding
description:
  KEGG: met:M446_3750 uroporphyrin-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; cob(II)yrinic acid a,c-diamide reductase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; nitroreductase.


ensembl_gene_id: Hden_2706
symbol: Hden_2706
gene_biotype: protein_coding
description:
  Rhodanese domain protein; KEGG: ana:all0384 hypothetical protein; PFAM: Rhodanese domain protein; SMART: Rhodanese domain protein; Belongs to the UPF0176 family.


ensembl_gene_id: Hden_2708
symbol: yacG
gene_biotype: protein_coding
description:
  Protein of unknown function DUF329; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C- terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.


ensembl_gene_id: Hden_2709
symbol: Hden_2709
gene_biotype: protein_coding
description:
  Maf protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.


ensembl_gene_id: Hden_2710
symbol: Hden_2710
gene_biotype: protein_coding
description:
  KEGG: Crp/Fnr family transcriptional regulator; PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding.


ensembl_gene_id: Hden_2711
symbol: Hden_2711
gene_biotype: protein_coding
description:
  KEGG: mbt:JTY_1638 membrane-anchored adenylyl cyclase; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase.


ensembl_gene_id: Hden_2713
symbol: hisD
gene_biotype: protein_coding
description:
  Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.


ensembl_gene_id: Hden_2715
symbol: murA
gene_biotype: protein_coding
description:
  UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.


ensembl_gene_id: Hden_2718
symbol: Hden_2718
gene_biotype: protein_coding
description:
  KEGG: msl:Msil_2464 efflux transporter, RND family, MFP subunit; TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: Hden_2719
symbol: Hden_2719
gene_biotype: protein_coding
description:
  KEGG: msl:Msil_2463 transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein.


ensembl_gene_id: Hden_2720
symbol: folE-2
gene_biotype: protein_coding
description:
  TIGRFAM: GTP cyclohydrolase I; KEGG: oca:OCAR_4254 GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I/Nitrile oxidoreductase.


ensembl_gene_id: Hden_2721
symbol: truA
gene_biotype: protein_coding
description:
  tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.


ensembl_gene_id: Hden_2723
symbol: fmt
gene_biotype: protein_coding
description:
  methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.


ensembl_gene_id: Hden_2724
symbol: def
gene_biotype: protein_coding
description:
  Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.


ensembl_gene_id: Hden_2726
symbol: Hden_2726
gene_biotype: protein_coding
description:
  KEGG: slo:Shew_1492 MATE efflux family protein; TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE.


ensembl_gene_id: Hden_2727
symbol: recR
gene_biotype: protein_coding
description:
  Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.


ensembl_gene_id: Hden_2728
symbol: Hden_2728
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.


ensembl_gene_id: Hden_2729
symbol: dnaX
gene_biotype: protein_coding
description:
  DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.


ensembl_gene_id: Hden_2730
symbol: Hden_2730
gene_biotype: protein_coding
description:
  PFAM: short-chain dehydrogenase/reductase SDR; KEGG: mlo:mlr6518 3-ketoacyl-(acyl-carrier-protein) reductase.


ensembl_gene_id: Hden_2731
symbol: Hden_2731
gene_biotype: protein_coding
description:
  KEGG: bja:bll1421 prephenate dehydratase; PFAM: prephenate dehydratase; amino acid-binding ACT domain protein.


ensembl_gene_id: Hden_2732
symbol: kdsB
gene_biotype: protein_coding
description:
  3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.


ensembl_gene_id: Hden_2734
symbol: Hden_2734
gene_biotype: protein_coding
description:
  PFAM: extracellular solute-binding protein family 5; KEGG: pla:Plav_0249 extracellular solute-binding protein.


ensembl_gene_id: Hden_2735
symbol: Hden_2735
gene_biotype: protein_coding
description:
  PFAM: extracellular solute-binding protein family 5; KEGG: pla:Plav_0248 extracellular solute-binding protein.


ensembl_gene_id: Hden_2736
symbol: Hden_2736
gene_biotype: protein_coding
description:
  PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rpb:RPB_1772 binding-protein-dependent transport systems inner membrane component.


ensembl_gene_id: Hden_2737
symbol: Hden_2737
gene_biotype: protein_coding
description:
  PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: mno:Mnod_4147 binding-protein-dependent transport systems inner membrane component.


ensembl_gene_id: Hden_2738
symbol: Hden_2738
gene_biotype: protein_coding
description:
  KEGG: rlg:Rleg_4449 ABC transporter related; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; Belongs to the ABC transporter superfamily.


ensembl_gene_id: Hden_2741
symbol: Hden_2741
gene_biotype: protein_coding
description:
  KEGG: rlg:Rleg_6820 nuclease (SNase domain protein); PFAM: nuclease (SNase domain protein); SMART: nuclease (SNase domain protein).


ensembl_gene_id: Hden_2744
symbol: Hden_2744
gene_biotype: protein_coding
description:
  PFAM: S-adenosylmethionine decarboxylase related; KEGG: pla:Plav_0582 S-adenosylmethionine decarboxylase related.


ensembl_gene_id: Hden_2746
symbol: Hden_2746
gene_biotype: protein_coding
description:
  KEGG: nwi:Nwi_2148 EmrB/QacA family drug resistance transporter; TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1.


ensembl_gene_id: Hden_2747
symbol: Hden_2747
gene_biotype: protein_coding
description:
  KEGG: mpo:Mpop_2031 coenzyme A transferase; PFAM: coenzyme A transferase; SMART: coenzyme A transferase.


ensembl_gene_id: Hden_2749
symbol: Hden_2749
gene_biotype: protein_coding
description:
  ATPase-like, ParA/MinD; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.


ensembl_gene_id: Hden_2750
symbol: mobA
gene_biotype: protein_coding
description:
  Molybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family.


ensembl_gene_id: Hden_2751
symbol: Hden_2751
gene_biotype: protein_coding
description:
  KEGG: avi:Avi_2069 molybdopterin-guanine dinucleotide biosynthesis protein B; TIGRFAM: molybdopterin-guanine dinucleotide biosynthesis protein B; PFAM: molybdopterin-guanine dinucleotide biosynthesis MobB region.


ensembl_gene_id: Hden_2752
symbol: moaA
gene_biotype: protein_coding
description:
  Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.


ensembl_gene_id: Hden_2753
symbol: Hden_2753
gene_biotype: protein_coding
description:
  KEGG: rpc:RPC_4869 response regulator receiver domain-containing protein; PFAM: response regulator receiver; SMART: response regulator receiver.


ensembl_gene_id: Hden_2754
symbol: Hden_2754
gene_biotype: protein_coding
description:
  TIGRFAM: hypoxanthine phosphoribosyltransferase; KEGG: xau:Xaut_0023 hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.


ensembl_gene_id: Hden_2755
symbol: ftsE
gene_biotype: protein_coding
description:
  Cell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division.


ensembl_gene_id: Hden_2758
symbol: Hden_2758
gene_biotype: protein_coding
description:
  KEGG: rpb:RPB_0837 phospholipid/glycerol acyltransferase; PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase.


ensembl_gene_id: Hden_2759
symbol: Hden_2759
gene_biotype: protein_coding
description:
  PFAM: small multidrug resistance protein; KEGG: gau:GAU_0989 quaternary ammonium compound-resistance protein.


ensembl_gene_id: Hden_2763
symbol: hisC
gene_biotype: protein_coding
description:
  KEGG: met:M446_5257 histidinol-phosphate aminotransferase; TIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.


ensembl_gene_id: Hden_2764
symbol: metXA
gene_biotype: protein_coding
description:
  Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.


ensembl_gene_id: Hden_2765
symbol: Hden_2765
gene_biotype: protein_coding
description:
  KEGG: nwi:Nwi_0586 methionine biosynthesis MetW; TIGRFAM: methionine biosynthesis protein MetW; PFAM: Methionine biosynthesis MetW protein.


ensembl_gene_id: Hden_2767
symbol: gloB
gene_biotype: protein_coding
description:
  Hydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.


ensembl_gene_id: Hden_2770
symbol: Hden_2770
gene_biotype: protein_coding
description:
  KEGG: rhi:NGR_c32710 acetoacetyl-CoA reductase; TIGRFAM: acetoacetyl-CoA reductase; PFAM: short-chain dehydrogenase/reductase SDR.


ensembl_gene_id: Hden_2771
symbol: Hden_2771
gene_biotype: protein_coding
description:
  TIGRFAM: acetyl-CoA acetyltransferase; KEGG: nwi:Nwi_3060 acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.


ensembl_gene_id: Hden_2772
symbol: Hden_2772
gene_biotype: protein_coding
description:
  KEGG: bid:Bind_0428 polyhydroxyalkonate synthesis repressor, PhaR; TIGRFAM: polyhydroxyalkanoate synthesis repressor PhaR; PFAM: PHA accumulation regulator DNA-binding protein; PHB accumulation regulatory domain protein.


ensembl_gene_id: Hden_2773
symbol: Hden_2773
gene_biotype: protein_coding
description:
  TIGRFAM: diguanylate cyclase; PFAM: EAL domain protein; GGDEF domain containing protein; KEGG: pla:Plav_1571 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); SMART: EAL domain protein; GGDEF domain containing protein.


ensembl_gene_id: Hden_2775
symbol: rpmF
gene_biotype: protein_coding
description:
  Ribosomal protein L32; KEGG: mmr:Mmar10_1411 50S ribosomal protein L32P; TIGRFAM: ribosomal protein L32; PFAM: ribosomal L32p protein; Belongs to the bacterial ribosomal protein bL32 family.


ensembl_gene_id: Hden_2776
symbol: mtgA
gene_biotype: protein_coding
description:
  Monofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family.


ensembl_gene_id: Hden_2777
symbol: Hden_2777
gene_biotype: protein_coding
description:
  PFAM: Polyprenyl synthetase; KEGG: mch:Mchl_2752 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.


ensembl_gene_id: Hden_2780
symbol: ispG
gene_biotype: protein_coding
description:
  1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family.


ensembl_gene_id: Hden_2782
symbol: znuC
gene_biotype: protein_coding
description:
  ABC transporter related protein; Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family.


ensembl_gene_id: Hden_2785
symbol: Hden_2785
gene_biotype: protein_coding
description:
  Ureidoglycolate lyase; KEGG: xau:Xaut_4106 5-carboxymethyl-2-hydroxymuconate delta-isomerase; PFAM: fumarylacetoacetate (FAA) hydrolase.


ensembl_gene_id: Hden_2790
symbol: Hden_2790
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: bid:Bind_2818 LysR family transcriptional regulator.


ensembl_gene_id: Hden_2792
symbol: gcvP
gene_biotype: protein_coding
description:
  Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.


ensembl_gene_id: Hden_2793
symbol: gcvH
gene_biotype: protein_coding
description:
  Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.


ensembl_gene_id: Hden_2794
symbol: Hden_2794
gene_biotype: protein_coding
description:
  KEGG: azc:AZC_4245 glycine cleavage system T protein; TIGRFAM: glycine cleavage system T protein; PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel.


ensembl_gene_id: Hden_2796
symbol: Hden_2796
gene_biotype: protein_coding
description:
  Heme oxygenase-like protein; KEGG: atc:AGR_C_4545 heme oxygenase; manually curated; PFAM: Haem oxygenase-like.


ensembl_gene_id: Hden_2797
symbol: Hden_2797
gene_biotype: protein_coding
description:
  KEGG: rlt:Rleg2_0221 methyl-accepting chemotaxis sensory transducer with cache sensor; PFAM: chemotaxis sensory transducer; Cache domain protein; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein.


ensembl_gene_id: Hden_2798
symbol: Hden_2798
gene_biotype: protein_coding
description:
  Integral membrane sensor signal transduction histidine kinase; KEGG: mno:Mnod_6193 histidine kinase; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein.


ensembl_gene_id: Hden_2799
symbol: Hden_2799
gene_biotype: protein_coding
description:
  KEGG: mno:Mnod_6194 two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; transcriptional regulator domain protein.


ensembl_gene_id: Hden_2807
symbol: ureD
gene_biotype: protein_coding
description:
  Urease accessory protein UreD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.


ensembl_gene_id: Hden_2808
symbol: ureG
gene_biotype: protein_coding
description:
  Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.


ensembl_gene_id: Hden_2809
symbol: ureC
gene_biotype: protein_coding
description:
  TIGRFAM: urease, alpha subunit; KEGG: mex:Mext_1197 urease subunit alpha; PFAM: amidohydrolase; Urease alpha-subunit domain protein.


ensembl_gene_id: Hden_2810
symbol: Hden_2810
gene_biotype: protein_coding
description:
  TIGRFAM: urease, gamma subunit; urease, beta subunit; KEGG: bbt:BBta_1961 bifunctional urease subunit gamma/beta; PFAM: Urease gamma subunit region; Urease beta subunit; Belongs to the urease gamma subunit family.


ensembl_gene_id: Hden_2811
symbol: ureF
gene_biotype: protein_coding
description:
  Urease accessory protein UreF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.


ensembl_gene_id: Hden_2813
symbol: Hden_2813
gene_biotype: protein_coding
description:
  TIGRFAM: urea ABC transporter, ATP-binding protein UrtE; PFAM: ABC transporter related; KEGG: rle:pRL120441 putative ABC transporter component; SMART: AAA ATPase.


ensembl_gene_id: Hden_2814
symbol: Hden_2814
gene_biotype: protein_coding
description:
  TIGRFAM: urea ABC transporter, ATP-binding protein UrtD; PFAM: ABC transporter related; KEGG: atc:AGR_pAT_797 probable ATP-binding component of ABC transporter; SMART: AAA ATPase.


ensembl_gene_id: Hden_2815
symbol: Hden_2815
gene_biotype: protein_coding
description:
  KEGG: atc:AGR_pAT_795 ABC transporter (permease); TIGRFAM: urea ABC transporter, permease protein UrtC; PFAM: inner-membrane translocator; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: Hden_2816
symbol: Hden_2816
gene_biotype: protein_coding
description:
  PFAM: inner-membrane translocator; KEGG: rle:pRL120444 putative permease component of ABC transporter; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: Hden_2819
symbol: Hden_2819
gene_biotype: protein_coding
description:
  PFAM: Extracellular ligand-binding receptor; KEGG: bra:BRADO5876 putative aliphatic amidase expression-regulating protein (AmiC).


ensembl_gene_id: Hden_2820
symbol: Hden_2820
gene_biotype: protein_coding
description:
  Integral membrane sensor signal transduction histidine kinase; KEGG: azl:AZL_a02790 two-component sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein.


ensembl_gene_id: Hden_2821
symbol: Hden_2821
gene_biotype: protein_coding
description:
  Two component transcriptional regulator, winged helix family; KEGG: sal:Sala_0801 two component transcriptional regulator; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; transcriptional regulator domain protein.


ensembl_gene_id: Hden_2822
symbol: Hden_2822
gene_biotype: protein_coding
description:
  TIGRFAM: efflux transporter, RND family, MFP subunit; KEGG: swi:Swit_3713 RND family efflux transporter MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: Hden_2823
symbol: Hden_2823
gene_biotype: protein_coding
description:
  KEGG: swi:Swit_3712 CzcA family heavy metal efflux protein; TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: Hden_2827
symbol: Hden_2827
gene_biotype: protein_coding
description:
  PFAM: Ferric reductase domain protein transmembrane component domain; Oxidoreductase FAD-binding domain protein; KEGG: dia:Dtpsy_0748 ferric reductase domain protein transmembrane component.


ensembl_gene_id: Hden_2829
symbol: Hden_2829
gene_biotype: protein_coding
description:
  KEGG: mpt:Mpe_A2975 BadM/Rrf2 family transcriptional regulator; TIGRFAM: transcriptional regulator, Rrf2 family; PFAM: protein of unknown function UPF0074.


ensembl_gene_id: Hden_2830
symbol: Hden_2830
gene_biotype: protein_coding
description:
  PFAM: bifunctional deaminase-reductase domain protein; KEGG: rlt:Rleg2_0711 bifunctional deaminase-reductase domain protein.


ensembl_gene_id: Hden_2832
symbol: Hden_2832
gene_biotype: protein_coding
description:
  KEGG: vap:Vapar_3221 transcriptional regulator, LuxR family; PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR.


ensembl_gene_id: Hden_2833
symbol: Hden_2833
gene_biotype: protein_coding
description:
  TIGRFAM: outer membrane autotransporter barrel domain protein; autotransporter-associated beta strand repeat protein; PFAM: Autotransporter beta- domain protein; KEGG: bcj:BCAM2169 putative outer membrane autotransporter; SMART: Autotransporter beta- domain protein.


ensembl_gene_id: Hden_2834
symbol: Hden_2834
gene_biotype: protein_coding
description:
  KEGG: nha:Nham_3292 TonB-dependent siderophore receptor; TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug.


ensembl_gene_id: Hden_2836
symbol: Hden_2836
gene_biotype: protein_coding
description:
  2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.


ensembl_gene_id: Hden_2838
symbol: aspS
gene_biotype: protein_coding
description:
  aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.


ensembl_gene_id: Hden_2839
symbol: rnd
gene_biotype: protein_coding
description:
  Ribonuclease D; Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides; Belongs to the RNase D family.


ensembl_gene_id: Hden_2840
symbol: Hden_2840
gene_biotype: protein_coding
description:
  KEGG: pzu:PHZ_p0115 heat shock protein DnaJ, N-terminal; PFAM: chaperone DnaJ domain protein; heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein.


ensembl_gene_id: Hden_2842
symbol: ppk
gene_biotype: protein_coding
description:
  Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family.


ensembl_gene_id: Hden_2845
symbol: Hden_2845
gene_biotype: protein_coding
description:
  PFAM: CDP-alcohol phosphatidyltransferase; KEGG: bra:BRADO3343 putative CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase (phosphatidylglycerophosphate synthase) (PGP synthase).


ensembl_gene_id: Hden_2847
symbol: purM
gene_biotype: protein_coding
description:
  TIGRFAM: phosphoribosylformylglycinamidine cyclo-ligase; KEGG: mno:Mnod_5547 phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein domain protein; AIR synthase related protein.


ensembl_gene_id: Hden_2848
symbol: Hden_2848
gene_biotype: protein_coding
description:
  TIGRFAM: PQQ-dependent dehydrogenase, methanol/ethanol family; PFAM: PQQ-dependent enzyme-like; Pyrrolo-quinoline quinone; KEGG: rpe:RPE_0851 pyrrolo-quinoline quinone; SMART: Pyrrolo-quinoline quinone beta-propeller repeat.


ensembl_gene_id: Hden_2851
symbol: purN
gene_biotype: protein_coding
description:
  Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.


ensembl_gene_id: Hden_2855
symbol: ndk
gene_biotype: protein_coding
description:
  Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.


ensembl_gene_id: Hden_2860
symbol: Hden_2860
gene_biotype: protein_coding
description:
  KEGG: nha:Nham_1796 chromate transporter; TIGRFAM: chromate transporter, chromate ion transporter (CHR) family; PFAM: Chromate transporter.


ensembl_gene_id: Hden_2861
symbol: glyS
gene_biotype: protein_coding
description:
  TIGRFAM: glycyl-tRNA synthetase, beta subunit; KEGG: mch:Mchl_3416 glycyl-tRNA synthetase, beta subunit.


ensembl_gene_id: Hden_2863
symbol: glyQ
gene_biotype: protein_coding
description:
  TIGRFAM: glycyl-tRNA synthetase, alpha subunit; KEGG: bra:BRADO2029 glycyl-tRNA synthetase subunit alpha; PFAM: glycyl-tRNA synthetase alpha subunit.


ensembl_gene_id: Hden_2866
symbol: Hden_2866
gene_biotype: protein_coding
description:
  PFAM: methyltransferase small; KEGG: mch:Mchl_3425 methyltransferase small; Belongs to the methyltransferase superfamily.


ensembl_gene_id: Hden_2868
symbol: Hden_2868
gene_biotype: protein_coding
description:
  PFAM: Polyprenyl synthetase; KEGG: bid:Bind_0855 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.


ensembl_gene_id: Hden_2869
symbol: ispE
gene_biotype: protein_coding
description:
  4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.


ensembl_gene_id: Hden_2870
symbol: Hden_2870
gene_biotype: protein_coding
description:
  KEGG: nwi:Nwi_2594 TPR repeat-containing protein; PFAM: TPR repeat-containing protein; SMART: Tetratricopeptide repeat.


ensembl_gene_id: Hden_2871
symbol: Hden_2871
gene_biotype: protein_coding
description:
  Electron-transferring-flavoprotein dehydrogenase; Accepts electrons from ETF and reduces ubiquinone.


ensembl_gene_id: Hden_2872
symbol: Hden_2872
gene_biotype: protein_coding
description:
  KEGG: azl:AZL_e02140 DNA polymerase bacteriophage-type; TIGRFAM: phage SPO1 DNA polymerase-related protein; PFAM: Uracil-DNA glycosylase superfamily.


ensembl_gene_id: Hden_2873
symbol: Hden_2873
gene_biotype: protein_coding
description:
  Transcription activator effector binding protein; KEGG: dvm:DvMF_1576 transcriptional regulator, AraC family; PFAM: transcription activator effector binding; SMART: transcription activator effector binding.


ensembl_gene_id: Hden_2874
symbol: Hden_2874
gene_biotype: protein_coding
description:
  Molybdenum cofactor biosynthesis protein B; May be involved in the biosynthesis of molybdopterin. Belongs to the MoaB/Mog family.


ensembl_gene_id: Hden_2876
symbol: Hden_2876
gene_biotype: protein_coding
description:
  KEGG: bmt:BSUIS_A0415 radical SAM domain-containing protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB.


ensembl_gene_id: Hden_2878
symbol: Hden_2878
gene_biotype: protein_coding
description:
  PFAM: DNA methylase N-4/N-6 domain protein; KEGG: pzu:PHZ_c0577 modification methylase; Belongs to the N(4)/N(6)-methyltransferase family.


ensembl_gene_id: Hden_2883
symbol: smc
gene_biotype: protein_coding
description:
  Chromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family.


ensembl_gene_id: Hden_2885
symbol: Hden_2885
gene_biotype: protein_coding
description:
  FoF1 ATP synthase, subunit I; A possible function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex.


ensembl_gene_id: Hden_2886
symbol: atpB
gene_biotype: protein_coding
description:
  ATP synthase F0, A subunit; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.


ensembl_gene_id: Hden_2887
symbol: atpE
gene_biotype: protein_coding
description:
  ATP synthase F0, C subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.


ensembl_gene_id: Hden_2888
symbol: atpF
gene_biotype: protein_coding
description:
  H+transporting two-sector ATPase B/B' subunit; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family.


ensembl_gene_id: Hden_2892
symbol: thrB
gene_biotype: protein_coding
description:
  TIGRFAM: homoserine kinase; KEGG: rce:RC1_3648 homoserine kinase; PFAM: aminoglycoside phosphotransferase; Belongs to the pseudomonas-type ThrB family.


ensembl_gene_id: Hden_2894
symbol: Hden_2894
gene_biotype: protein_coding
description:
  Redoxin domain protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.


ensembl_gene_id: Hden_2896
symbol: Hden_2896
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF179; KEGG: oca:OCAR_7326 hypothetical protein; Belongs to the UPF0301 (AlgH) family.


ensembl_gene_id: Hden_2897
symbol: Hden_2897
gene_biotype: protein_coding
description:
  Diguanylate cyclase/phosphodiesterase with PAS/PAC and periplasmic/7TM domain sensor(s); TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; Diverse 7TM receptor extracellular region 2; Diverse 7TM receptor transmembrane region; GGDEF domain containing protein; PAS fold-3 domain protein; KEGG: msl:Msil_1254 diguanylate cyclase/phosphodiesterase; SMART: EAL domain protein; GGDEF domain containing protein; PAC repeat-containing protein.


ensembl_gene_id: Hden_2898
symbol: Hden_2898
gene_biotype: protein_coding
description:
  KEGG: azc:AZC_2241 ribosomal-protein-alanine N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase.


ensembl_gene_id: Hden_2899
symbol: Hden_2899
gene_biotype: protein_coding
description:
  Processing peptidase; KEGG: azc:AZC_2240 mitochondrial processing peptidase-like protein; PFAM: peptidase M16 domain protein.


ensembl_gene_id: Hden_2900
symbol: Hden_2900
gene_biotype: protein_coding
description:
  TIGRFAM: threonine synthase; KEGG: xau:Xaut_3524 threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit.


ensembl_gene_id: Hden_2904
symbol: ctaG
gene_biotype: protein_coding
description:
  Cytochrome c oxidase assembly protein CtaG/Cox11; Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I; Belongs to the COX11/CtaG family.


ensembl_gene_id: Hden_2906
symbol: ctaB
gene_biotype: protein_coding
description:
  Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.


ensembl_gene_id: Hden_2907
symbol: Hden_2907
gene_biotype: protein_coding
description:
  Cytochrome c oxidase, subunit I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.


ensembl_gene_id: Hden_2908
symbol: Hden_2908
gene_biotype: protein_coding
description:
  Cytochrome c oxidase, subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).


ensembl_gene_id: Hden_2909
symbol: Hden_2909
gene_biotype: protein_coding
description:
  PFAM: Invasion associated locus B family protein; KEGG: xau:Xaut_4649 invasion associated locus B family protein.


ensembl_gene_id: Hden_2912
symbol: Hden_2912
gene_biotype: protein_coding
description:
  Hypothetical protein; KEGG: oaa:100075777 similar to WW domain-containing adapter protein with coiled-coil.


ensembl_gene_id: Hden_2914
symbol: Hden_2914
gene_biotype: protein_coding
description:
  KEGG: met:M446_0428 RND family efflux transporter MFP subunit; TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: Hden_2915
symbol: Hden_2915
gene_biotype: protein_coding
description:
  PFAM: acriflavin resistance protein; KEGG: met:M446_0427 acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: Hden_2918
symbol: Hden_2918
gene_biotype: protein_coding
description:
  KEGG: bbt:BBta_7063 putative ABC transporter, ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase.


ensembl_gene_id: Hden_2919
symbol: Hden_2919
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF214; KEGG: bbt:BBta_7062 putative ABC transporter, permease protein.


ensembl_gene_id: Hden_2925
symbol: Hden_2925
gene_biotype: protein_coding
description:
  KEGG: sal:Sala_0171 para-aminobenzoate synthase, component I; TIGRFAM: para-aminobenzoate synthase, subunit I; PFAM: Chorismate binding-like; aminotransferase class IV.


ensembl_gene_id: Hden_2927
symbol: Hden_2927
gene_biotype: protein_coding
description:
  Putative signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: PAS fold-4 domain protein; ATP-binding region ATPase domain protein; KEGG: gox:GOX0315 sensory transduction histidine kinase; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein.


ensembl_gene_id: Hden_2928
symbol: Hden_2928
gene_biotype: protein_coding
description:
  PFAM: Mg2 transporter protein CorA family protein; KEGG: mlo:mlr9579 magnesium and cobalt transport protein.


ensembl_gene_id: Hden_2931
symbol: kdpA
gene_biotype: protein_coding
description:
  Potassium-transporting ATPase, A subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane.


ensembl_gene_id: Hden_2932
symbol: kdpB
gene_biotype: protein_coding
description:
  K+-transporting ATPase, B subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.


ensembl_gene_id: Hden_2933
symbol: kdpC
gene_biotype: protein_coding
description:
  Potassium-transporting ATPase, C subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.


ensembl_gene_id: Hden_2934
symbol: Hden_2934
gene_biotype: protein_coding
description:
  KEGG: sme:SMa2327 sensor protein; PFAM: Osmosensitive K channel His kinase sensor; ATP-binding region ATPase domain protein; UspA domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein.


ensembl_gene_id: Hden_2935
symbol: Hden_2935
gene_biotype: protein_coding
description:
  Two component transcriptional regulator, winged helix family; KEGG: smd:Smed_5362 two component transcriptional regulator; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; transcriptional regulator domain protein.


ensembl_gene_id: Hden_2936
symbol: Hden_2936
gene_biotype: protein_coding
description:
  KEGG: oan:Oant_4139 GntR family transcriptional regulator; PFAM: regulatory protein GntR HTH; aminotransferase class I and II; SMART: regulatory protein GntR HTH.


ensembl_gene_id: Hden_2942
symbol: Hden_2942
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF1214; protein of unknown function DUF1254; KEGG: nha:Nham_2980 hypothetical protein.


ensembl_gene_id: Hden_2943
symbol: Hden_2943
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF1214; protein of unknown function DUF1254; KEGG: rme:Rmet_5225 hypothetical protein.


ensembl_gene_id: Hden_2945
symbol: Hden_2945
gene_biotype: protein_coding
description:
  PFAM: secretion protein HlyD family protein; KEGG: nha:Nham_2977 secretion protein HlyD; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: Hden_2947
symbol: Hden_2947
gene_biotype: protein_coding
description:
  KEGG: mlo:mlr2855 two-component response regulator; PFAM: ANTAR domain protein; response regulator receiver; SMART: response regulator receiver.


ensembl_gene_id: Hden_2951
symbol: Hden_2951
gene_biotype: protein_coding
description:
  KEGG: ret:RHE_CH01782 nitrite reductase [NAD(P)H], large subunit protein; TIGRFAM: nitrite reductase [NAD(P)H], large subunit; PFAM: nitrite and sulphite reductase 4Fe-4S region; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; BFD domain protein [2Fe-2S]-binding domain protein; nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein.


ensembl_gene_id: Hden_2952
symbol: Hden_2952
gene_biotype: protein_coding
description:
  KEGG: mlo:mlr2863 nitrite reductase small subunit; TIGRFAM: nitrite reductase [NAD(P)H], small subunit; PFAM: Rieske [2Fe-2S] iron-sulphur domain.


ensembl_gene_id: Hden_2953
symbol: Hden_2953
gene_biotype: protein_coding
description:
  PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; BFD domain protein [2Fe-2S]-binding domain protein; KEGG: rlg:Rleg_1627 molybdopterin oxidoreductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.


ensembl_gene_id: Hden_2966
symbol: Hden_2966
gene_biotype: protein_coding
description:
  PFAM: Phage tail tape measure protein, conserved region; KEGG: dvu:DVU2157 tail tape measure protein, putative.


ensembl_gene_id: Hden_2972
symbol: Hden_2972
gene_biotype: protein_coding
description:
  Phage head-tail adaptor; KEGG: vap:Vapar_2478 putative head-tail adaptor protein; TIGRFAM: phage head-tail adaptor; PFAM: putative head-tail adaptor protein.


ensembl_gene_id: Hden_2978
symbol: Hden_2978
gene_biotype: protein_coding
description:
  KEGG: rpe:RPE_1908 HK97 family phage major capsid protein; TIGRFAM: phage major capsid protein, HK97 family; PFAM: major capsid protein HK97.


ensembl_gene_id: Hden_2979
symbol: Hden_2979
gene_biotype: protein_coding
description:
  KEGG: sit:TM1040_1060 peptidase U35, phage prohead HK97; TIGRFAM: phage prohead protease, HK97 family; PFAM: peptidase U35 phage prohead HK97.


ensembl_gene_id: Hden_2983
symbol: Hden_2983
gene_biotype: protein_coding
description:
  KEGG: dvl:Dvul_0869 HK97 family phage portal protein; TIGRFAM: phage portal protein, HK97 family; PFAM: portal protein.


ensembl_gene_id: Hden_3002
symbol: Hden_3002
gene_biotype: protein_coding
description:
  Hypothetical protein; KEGG: htu:Htur_3193 RecA-superfamily ATPase implicated in signal transduction-like protein.


ensembl_gene_id: Hden_3010
symbol: Hden_3010
gene_biotype: protein_coding
description:
  SNF2-related protein; KEGG: pfs:pQBR0371 putative helicase; PFAM: SNF2-related protein; SMART: DEAD-like helicase.


ensembl_gene_id: Hden_3013
symbol: Hden_3013
gene_biotype: protein_coding
description:
  PFAM: MT-A70 family protein; KEGG: rsh:Rsph17029_0660 MT-A70 family protein; Belongs to the MT-A70-like family.


ensembl_gene_id: Hden_3015
symbol: Hden_3015
gene_biotype: protein_coding
description:
  PFAM: C-5 cytosine-specific DNA methylase; KEGG: slt:Slit_1955 C-5 cytosine-specific DNA methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.


ensembl_gene_id: Hden_3023
symbol: Hden_3023
gene_biotype: protein_coding
description:
  Hypothetical protein; Manually curated; KEGG: mrd:Mrad2831_0002 chromosomal replication initiation protein.


ensembl_gene_id: Hden_3027
symbol: Hden_3027
gene_biotype: protein_coding
description:
  KEGG: mno:Mnod_1018 exonuclease RNase T and DNA polymerase III; PFAM: Exonuclease RNase T and DNA polymerase III; SMART: Exonuclease.


ensembl_gene_id: Hden_3041
symbol: Hden_3041
gene_biotype: protein_coding
description:
  KEGG: bpt:Bpet0307 MarR family transcriptional regulator; PFAM: regulatory protein MarR; SMART: regulatory protein MarR.


ensembl_gene_id: Hden_3043
symbol: Hden_3043
gene_biotype: protein_coding
description:
  precorrin-6A synthase (deacetylating); Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A.


ensembl_gene_id: Hden_3044
symbol: Hden_3044
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: azl:AZL_c04930 transcriptional regulator.


ensembl_gene_id: Hden_3045
symbol: Hden_3045
gene_biotype: protein_coding
description:
  KEGG: met:M446_2368 flavoprotein WrbA; TIGRFAM: flavoprotein WrbA; PFAM: flavodoxin/nitric oxide synthase.


ensembl_gene_id: Hden_3049
symbol: Hden_3049
gene_biotype: protein_coding
description:
  PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Rieske [2Fe-2S] iron-sulphur domain; KEGG: reh:H16_B0945 pyridine nucleotide-disulphide oxidoreductase.


ensembl_gene_id: Hden_3050
symbol: Hden_3050
gene_biotype: protein_coding
description:
  PFAM: Ferritin Dps family protein; KEGG: rlt:Rleg2_4342 ferritin Dps family protein; Belongs to the Dps family.


ensembl_gene_id: Hden_3055
symbol: Hden_3055
gene_biotype: protein_coding
description:
  TIGRFAM: nucleotide sugar dehydrogenase; KEGG: pzu:PHZ_c2961 UDP-glucose 6-dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation.


ensembl_gene_id: Hden_3056
symbol: flhA
gene_biotype: protein_coding
description:
  Flagellar biosynthesis protein FlhA; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.


ensembl_gene_id: Hden_3057
symbol: Hden_3057
gene_biotype: protein_coding
description:
  PFAM: type III secretion system inner membrane R protein; KEGG: bid:Bind_3589 flagellar biosynthesis protein FliR.


ensembl_gene_id: Hden_3064
symbol: cheD
gene_biotype: protein_coding
description:
  CheD; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.


ensembl_gene_id: Hden_3065
symbol: Hden_3065
gene_biotype: protein_coding
description:
  KEGG: bid:Bind_3627 response regulator receiver protein; PFAM: response regulator receiver; SMART: response regulator receiver.


ensembl_gene_id: Hden_3066
symbol: cheB
gene_biotype: protein_coding
description:
  Response regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.


ensembl_gene_id: Hden_3067
symbol: Hden_3067
gene_biotype: protein_coding
description:
  MCP methyltransferase, CheR-type; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.


ensembl_gene_id: Hden_3069
symbol: Hden_3069
gene_biotype: protein_coding
description:
  KEGG: acr:Acry_2708 CheA signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; Signal transducing histidine kinase homodimeric; Hpt domain protein; CheW domain protein; SMART: CheW domain protein; Hpt domain protein; ATP-binding region ATPase domain protein.


ensembl_gene_id: Hden_3070
symbol: Hden_3070
gene_biotype: protein_coding
description:
  KEGG: response regulator receiver protein; PFAM: response regulator receiver; SMART: response regulator receiver.


ensembl_gene_id: Hden_3072
symbol: Hden_3072
gene_biotype: protein_coding
description:
  KEGG: pzu:PHZ_c3382 methyl-accepting chemotaxis protein McpA; PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein.


ensembl_gene_id: Hden_3073
symbol: Hden_3073
gene_biotype: protein_coding
description:
  Type IV pilus assembly PilZ; KEGG: mpo:Mpop_0517 hypothetical protein; manually curated; PFAM: type IV pilus assembly PilZ.


ensembl_gene_id: Hden_3074
symbol: Hden_3074
gene_biotype: protein_coding
description:
  Diguanylate phosphodiesterase; TIGRFAM: PAS sensor protein; PFAM: EAL domain protein; PAS fold domain protein; KEGG: mch:Mchl_3001 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); SMART: EAL domain protein; PAC repeat-containing protein; PAS domain containing protein.


ensembl_gene_id: Hden_3075
symbol: Hden_3075
gene_biotype: protein_coding
description:
  PFAM: type IV pilus assembly PilZ; KEGG: swi:Swit_3968 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s).


ensembl_gene_id: Hden_3076
symbol: Hden_3076
gene_biotype: protein_coding
description:
  Diguanylate cyclase; SMART: GGDEF domain containing protein; TIGRFAM: diguanylate cyclase; KEGG: bra:BRADO3548 hypothetical protein; PFAM: GGDEF domain containing protein.


ensembl_gene_id: Hden_3077
symbol: Hden_3077
gene_biotype: protein_coding
description:
  KEGG: azc:AZC_0653 flagellar biosynthesis protein FliQ; TIGRFAM: flagellar biosynthetic protein FliQ; PFAM: export protein FliQ family 3.


ensembl_gene_id: Hden_3078
symbol: Hden_3078
gene_biotype: protein_coding
description:
  PFAM: flagellar hook capping protein; KEGG: bid:Bind_3552 flagellar basal body rod modification protein.


ensembl_gene_id: Hden_3080
symbol: Hden_3080
gene_biotype: protein_coding
description:
  PFAM: flagellar FlaF family protein; KEGG: mes:Meso_0276 flagellar biosynthesis regulatory protein FlaF.


ensembl_gene_id: Hden_3081
symbol: Hden_3081
gene_biotype: protein_coding
description:
  Flagellar hook-associated 3 family protein; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.


ensembl_gene_id: Hden_3082
symbol: flgK
gene_biotype: protein_coding
description:
  KEGG: bja:bll6857 flagellar hook-associated protein FlgK; TIGRFAM: flagellar hook-associated protein FlgK; PFAM: protein of unknown function DUF1078 domain protein.


ensembl_gene_id: Hden_3083
symbol: Hden_3083
gene_biotype: protein_coding
description:
  KEGG: mlo:mlr2937 flagellar hook protein FlgE; TIGRFAM: flagellar hook-basal body protein; PFAM: flagellar basal body FlaE domain protein; protein of unknown function DUF1078 domain protein; flagellar basal body rod protein.


ensembl_gene_id: Hden_3084
symbol: Hden_3084
gene_biotype: protein_coding
description:
  Two component transcriptional regulator, winged helix family; KEGG: ara:Arad_0907 two-component response regulator protein; PFAM: transcriptional regulator domain protein; SMART: transcriptional regulator domain protein.


ensembl_gene_id: Hden_3088
symbol: Hden_3088
gene_biotype: protein_coding
description:
  Hypothetical protein; KEGG: ele:Elen_1721 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC.


ensembl_gene_id: Hden_3089
symbol: Hden_3089
gene_biotype: protein_coding
description:
  PFAM: flagellar hook-length control protein; KEGG: sme:SMc03044 chemotaxis protein (motility protein D).


ensembl_gene_id: Hden_3093
symbol: Hden_3093
gene_biotype: protein_coding
description:
  Flagellar M-ring protein FliF; The M ring may be actively involved in energy transduction. Belongs to the FliF family.


ensembl_gene_id: Hden_3094
symbol: Hden_3094
gene_biotype: protein_coding
description:
  Flagellin domain protein; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.


ensembl_gene_id: Hden_3095
symbol: fliP
gene_biotype: protein_coding
description:
  Flagellar biosynthetic protein FliP; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family.


ensembl_gene_id: Hden_3096
symbol: Hden_3096
gene_biotype: protein_coding
description:
  Flagellar basal body-associated protein FliL; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.


ensembl_gene_id: Hden_3097
symbol: flgH
gene_biotype: protein_coding
description:
  Flagellar L-ring protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.


ensembl_gene_id: Hden_3099
symbol: flgI
gene_biotype: protein_coding
description:
  Flagellar P-ring protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.


ensembl_gene_id: Hden_3100
symbol: Hden_3100
gene_biotype: protein_coding
description:
  Flagella basal body P-ring formation protein FlgA; Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P- ring assembly; Belongs to the FlgA family.


ensembl_gene_id: Hden_3101
symbol: Hden_3101
gene_biotype: protein_coding
description:
  KEGG: rhi:NGR_c02770 flagellar basal-body rod protein FlgG; TIGRFAM: flagellar basal-body rod protein FlgG; flagellar hook-basal body protein; PFAM: protein of unknown function DUF1078 domain protein; flagellar basal body rod protein; Belongs to the flagella basal body rod proteins family.


ensembl_gene_id: Hden_3102
symbol: fliE
gene_biotype: protein_coding
description:
  PFAM: flagellar hook-basal body complex protein FliE; KEGG: azc:AZC_0635 flagellar hook-basal body protein FliE.


ensembl_gene_id: Hden_3103
symbol: Hden_3103
gene_biotype: protein_coding
description:
  KEGG: msl:Msil_0025 flagellar basal body rod protein FlgC; TIGRFAM: flagellar basal-body rod protein FlgC; PFAM: protein of unknown function DUF1078 domain protein; flagellar basal body rod protein; Belongs to the flagella basal body rod proteins family.


ensembl_gene_id: Hden_3104
symbol: Hden_3104
gene_biotype: protein_coding
description:
  Flagellar basal body rod protein; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.


ensembl_gene_id: Hden_3108
symbol: Hden_3108
gene_biotype: protein_coding
description:
  PFAM: surface presentation of antigens (SPOA) protein; KEGG: mch:Mchl_0650 flagellar motor switch protein FliN.


ensembl_gene_id: Hden_3109
symbol: Hden_3109
gene_biotype: protein_coding
description:
  PFAM: surface presentation of antigens (SPOA) protein; flagellar motor switch protein FliM; KEGG: met:M446_3213 flagellar motor switch protein FliM.


ensembl_gene_id: Hden_3111
symbol: Hden_3111
gene_biotype: protein_coding
description:
  KEGG: bid:Bind_2810 flagellar basal body rod protein; TIGRFAM: flagellar basal-body rod protein FlgF; flagellar hook-basal body protein; PFAM: flagellar basal body rod protein; Belongs to the flagella basal body rod proteins family.


ensembl_gene_id: Hden_3112
symbol: Hden_3112
gene_biotype: protein_coding
description:
  TIGRFAM: ATPase, FliI/YscN family; PFAM: H+transporting two-sector ATPase alpha/beta subunit central region; KEGG: msl:Msil_1657 flagellum-specific ATP synthase; SMART: AAA ATPase.


ensembl_gene_id: Hden_3114
symbol: Hden_3114
gene_biotype: protein_coding
description:
  Putative signal transduction protein with CBS domains; KEGG: rce:RC1_0504 hypothetical protein; PFAM: CBS domain containing protein; Haloacid dehalogenase domain protein hydrolase; SMART: CBS domain containing protein.


ensembl_gene_id: Hden_3116
symbol: Hden_3116
gene_biotype: protein_coding
description:
  KEGG: gbe:GbCGDNIH1_0177 sarcosine oxidase beta subunit; TIGRFAM: sarcosine oxidase, beta subunit family; PFAM: FAD dependent oxidoreductase.


ensembl_gene_id: Hden_3117
symbol: Hden_3117
gene_biotype: protein_coding
description:
  PFAM: Sarcosine oxidase delta subunit heterotetrameric; KEGG: xau:Xaut_4701 sarcosine oxidase delta subunit heterotetrameric.


