# pathwayInfo

id: SM00847
description: Helicase associated domain (HA2) Add an annotation
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00847
name:
  Protein Domains (SMART).STRING_v12.0_585425_STRINGid_SM00847_Helicase_associated_domain_(HA2)__Add_an_annotation


id: SM00858
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00858
name:
  Protein Domains (SMART).STRING_v12.0_585425_STRINGid_SM00858_This_domain_family_includes_a_range_of_different_proteins._Such_as_antifreeze_proteins_and_flagellar_FlgA_proteins,_and_CpaB_pilus_proteins.

description:
  This domain family includes a range of different proteins. Such as antifreeze proteins and flagellar FlgA proteins, and CpaB pilus proteins.


id: SM00859
description: Semialdehyde dehydrogenase, NAD binding domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00859
name:
  Protein Domains (SMART).STRING_v12.0_585425_STRINGid_SM00859_Semialdehyde_dehydrogenase,_NAD_binding_domain


id: SM00861
description: Transketolase, pyrimidine binding domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00861
name:
  Protein Domains (SMART).STRING_v12.0_585425_STRINGid_SM00861_Transketolase,_pyrimidine_binding_domain


id: SM00862
description: Transcriptional regulatory protein, C terminal
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00862
name:
  Protein Domains (SMART).STRING_v12.0_585425_STRINGid_SM00862_Transcriptional_regulatory_protein,_C_terminal


id: SM00863
description: Threonyl and Alanyl tRNA synthetase second additional domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00863
name:
  Protein Domains (SMART).STRING_v12.0_585425_STRINGid_SM00863_Threonyl_and_Alanyl_tRNA_synthetase_second_additional_domain


id: SM00870
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00870
name:
  Protein Domains (SMART).STRING_v12.0_585425_STRINGid_SM00870_Asparaginase,_which_is_found_in_various_plant,_animal_and_bacterial_cells,_catalyses_the_deamination_of_asparagine_to_yield_aspartic_acid_and_an_ammonium_ion,_resulting_in_a_depletion_of_free_circulatory_asparagine_in_plasma_PUBMED:3026924._The_...

description:
  Asparaginase, which is found in various plant, animal and bacterial cells, catalyses the deamination of asparagine to yield aspartic acid and an ammonium ion, resulting in a depletion of free circulatory asparagine in plasma PUBMED:3026924. The ...


id: SM00876
description: Biotin and Thiamin Synthesis associated domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00876
name:
  Protein Domains (SMART).STRING_v12.0_585425_STRINGid_SM00876_Biotin_and_Thiamin_Synthesis_associated_domain


id: SM00877
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00877
name:
  Protein Domains (SMART).STRING_v12.0_585425_STRINGid_SM00877_Bacterial_microcompartments_are_primitive_organelles_composed_entirely_of_protein_subunits._The_prototypical_bacterial_microcompartment_is_the_carboxysome,_a_protein_shell_for_sequestering_carbon_fixation_reactions._These_proteins_for_hexameric_...

description:
  Bacterial microcompartments are primitive organelles composed entirely of protein subunits. The prototypical bacterial microcompartment is the carboxysome, a protein shell for sequestering carbon fixation reactions. These proteins for hexameric ...


id: SM00896
description: Ferredoxin-fold anticodon binding domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00896
name:
  Protein Domains (SMART).STRING_v12.0_585425_STRINGid_SM00896_Ferredoxin-fold_anticodon_binding_domain


id: SM00898
description: Formamidopyrimidine-DNA glycosylase N-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00898
name:
  Protein Domains (SMART).STRING_v12.0_585425_STRINGid_SM00898_Formamidopyrimidine-DNA_glycosylase_N-terminal_domain


id: SM00922
description: Mandelate racemase / muconate lactonizing enzyme, C-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00922
name:
  Protein Domains (SMART).STRING_v12.0_585425_STRINGid_SM00922_Mandelate_racemase_/_muconate_lactonizing_enzyme,_C-terminal_domain


id: SM00934
description: Orotidine 5-phosphate decarboxylase / HUMPS family
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00934
name:
  Protein Domains (SMART).STRING_v12.0_585425_STRINGid_SM00934_Orotidine_5-phosphate_decarboxylase_/_HUMPS_family


id: SM00937
description: This domain is found in peptide chain release factors.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00937
name:
  Protein Domains (SMART).STRING_v12.0_585425_STRINGid_SM00937_This_domain_is_found_in_peptide_chain_release_factors.


id: SM00939
description: X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00939
name:
  Protein Domains (SMART).STRING_v12.0_585425_STRINGid_SM00939_X-Pro_dipeptidyl-peptidase_C-terminal_non-catalytic_domain


id: SM00955
description: This domain is the catalytic domain of ribonuclease II.PUBMED:16806266
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00955
name:
  Protein Domains (SMART).STRING_v12.0_585425_STRINGid_SM00955_This_domain_is_the_catalytic_domain_of_ribonuclease_II.PUBMED:16806266


id: SM00959
description: Rho termination factor, N-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00959
name:
  Protein Domains (SMART).STRING_v12.0_585425_STRINGid_SM00959_Rho_termination_factor,_N-terminal_domain


id: SM00961
description: Ribulose bisphosphate carboxylase, small chain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00961
name:
  Protein Domains (SMART).STRING_v12.0_585425_STRINGid_SM00961_Ribulose_bisphosphate_carboxylase,_small_chain


id: SM00963
description: SRP54-type protein, helical bundle domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00963
name:
  Protein Domains (SMART).STRING_v12.0_585425_STRINGid_SM00963_SRP54-type_protein,_helical_bundle_domain


id: SM00967
description: RNA 2-O ribose methyltransferase substrate binding
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00967
name:
  Protein Domains (SMART).STRING_v12.0_585425_STRINGid_SM00967_RNA_2-O_ribose_methyltransferase_substrate_binding


id: SM00981
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00981
name:
  Protein Domains (SMART).STRING_v12.0_585425_STRINGid_SM00981_The_THUMP_domain_is_named_after_after_thiouridine_synthases,_methylases_and_PSUSs_PUBMED:11295541._The_THUMP_domain_consists_of_about_110_amino_acid_residues._The_structure_of_ThiI_reveals_that_the_THUMP_has_a_fold_unlike_that_of_previously_...

description:
  The THUMP domain is named after after thiouridine synthases, methylases and PSUSs PUBMED:11295541. The THUMP domain consists of about 110 amino acid residues. The structure of ThiI reveals that the THUMP has a fold unlike that of previously ...


id: SM00982
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00982
name:
  Protein Domains (SMART).STRING_v12.0_585425_STRINGid_SM00982_This_domain_is_found_in_proteins_necessary_for_strand-specific_repair_in_DNA_such_as_TRCF_in_Escherichia_coli._A_lesion_in_the_template_strand_blocks_the_RNA_polymerase_complex_(RNAP)._The_RNAP-DNA-RNA_complex_is_specifically_recognised_by_the_...

description:
  This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli. A lesion in the template strand blocks the RNA polymerase complex (RNAP). The RNAP-DNA-RNA complex is specifically recognised by the ...


id: SM00987
description: UreE urease accessory protein, C-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00987
name:
  Protein Domains (SMART).STRING_v12.0_585425_STRINGid_SM00987_UreE_urease_accessory_protein,_C-terminal_domain


id: SM00988
description: UreE urease accessory protein, N-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00988
name:
  Protein Domains (SMART).STRING_v12.0_585425_STRINGid_SM00988_UreE_urease_accessory_protein,_N-terminal_domain


id: SM00997
description: S-adenosyl-L-homocysteine hydrolase, NAD binding domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00997
name:
  Protein Domains (SMART).STRING_v12.0_585425_STRINGid_SM00997_S-adenosyl-L-homocysteine_hydrolase,_NAD_binding_domain


id: SM01002
description: Alanine dehydrogenase/PNT, C-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01002
name:
  Protein Domains (SMART).STRING_v12.0_585425_STRINGid_SM01002_Alanine_dehydrogenase/PNT,_C-terminal_domain


id: SM01003
description: Alanine dehydrogenase/PNT, N-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01003
name:
  Protein Domains (SMART).STRING_v12.0_585425_STRINGid_SM01003_Alanine_dehydrogenase/PNT,_N-terminal_domain


id: SM01007
description: Class II Aldolase and Adducin N-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01007
name:
  Protein Domains (SMART).STRING_v12.0_585425_STRINGid_SM01007_Class_II_Aldolase_and_Adducin_N-terminal_domain


id: SM01080
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01080
name:
  Protein Domains (SMART).STRING_v12.0_585425_STRINGid_SM01080_CHASE2_is_an_extracellular_sensory_domain,_which_is_present_in_various_classes_of_transmembrane_receptors_that_are_parts_of_signal_transduction_pathways_in_bacteria._Specifically,_CHASE2_domains_are_found_in_histidine_kinases,_adenylate_cyclases,_...

description:
  CHASE2 is an extracellular sensory domain, which is present in various classes of transmembrane receptors that are parts of signal transduction pathways in bacteria. Specifically, CHASE2 domains are found in histidine kinases, adenylate cyclases, ...


id: SM01086
description: C-terminal, D2-small domain, of ClpB protein
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01086
name:
  Protein Domains (SMART).STRING_v12.0_585425_STRINGid_SM01086_C-terminal,_D2-small_domain,_of_ClpB_protein


id: SM01096
description: Carbamoyl-phosphate synthetase large chain, oligomerisation domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01096
name:
  Protein Domains (SMART).STRING_v12.0_585425_STRINGid_SM01096_Carbamoyl-phosphate_synthetase_large_chain,_oligomerisation_domain


id: SM01097
description: Carbamoyl-phosphate synthase small chain, CPSase domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01097
name:
  Protein Domains (SMART).STRING_v12.0_585425_STRINGid_SM01097_Carbamoyl-phosphate_synthase_small_chain,_CPSase_domain


id: SM01116
description: Cyanate lyase C-terminal domain, Cyanate hydratase
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01116
name:
  Protein Domains (SMART).STRING_v12.0_585425_STRINGid_SM01116_Cyanate_lyase_C-terminal_domain,_Cyanate_hydratase


id: SM01118
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01118
name:
  Protein Domains (SMART).STRING_v12.0_585425_STRINGid_SM01118_These_sequences_are_functionally_identified_as_members_of_the_adenylate_cyclase_family,_which_catalyses_the_conversion_of_ATP_to_3,5-cyclic_AMP_and_pyrophosphate._Six_distinct_non-homologous_classes_of_AC_have_been_identified._The_structure_of_...

description:
  These sequences are functionally identified as members of the adenylate cyclase family, which catalyses the conversion of ATP to 3,5-cyclic AMP and pyrophosphate. Six distinct non-homologous classes of AC have been identified. The structure of ...


id: SM01142
description: This C terminal domain is found in DOB1/SK12/helY-like DEAD box helicases [PUBMED:15112237].
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01142
name:
  Protein Domains (SMART).STRING_v12.0_585425_STRINGid_SM01142_This_C_terminal_domain_is_found_in_DOB1/SK12/helY-like_DEAD_box_helicases_[PUBMED:15112237].


id: SM01204
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01204
name:
  Protein Domains (SMART).STRING_v12.0_585425_STRINGid_SM01204_The_FIST_C_domain_is_a_novel_sensory_domain,_which_is_present_in_signal_transduction_proteins_from_Bacteria,_Archaea_and_Eukarya._Chromosomal_proximity_of_FIST-encoding_genes_to_those_coding_for_proteins_involved_in_amino_acid_metabolism_and_...

description:
  The FIST C domain is a novel sensory domain, which is present in signal transduction proteins from Bacteria, Archaea and Eukarya. Chromosomal proximity of FIST-encoding genes to those coding for proteins involved in amino acid metabolism and ...


id: SM01209
description: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01209
name:
  Protein Domains (SMART).STRING_v12.0_585425_STRINGid_SM01209_Phosphoribosylglycinamide_synthetase,_ATP-grasp_(A)_domain


id: SM01210
description: Phosphoribosylglycinamide synthetase, C domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01210
name:
  Protein Domains (SMART).STRING_v12.0_585425_STRINGid_SM01210_Phosphoribosylglycinamide_synthetase,_C_domain


id: SM01211
description: CobB/CobQ-like glutamine amidotransferase domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01211
name:
  Protein Domains (SMART).STRING_v12.0_585425_STRINGid_SM01211_CobB/CobQ-like_glutamine_amidotransferase_domain


id: SM01232
description: Formamidopyrimidine-DNA glycosylase H2TH domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01232
name:
  Protein Domains (SMART).STRING_v12.0_585425_STRINGid_SM01232_Formamidopyrimidine-DNA_glycosylase_H2TH_domain


id: SM01234
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01234
name:
  Protein Domains (SMART).STRING_v12.0_585425_STRINGid_SM01234_This_domain_has_haemolytic_activity_(PMID:19306042)._It_is_found_in_short_(73-103_amino_acid)_proteins_and_contains_three_conserved_cysteine_residues.

description:
  This domain has haemolytic activity (PMID:19306042). It is found in short (73-103 amino acid) proteins and contains three conserved cysteine residues.


id: SM01240
description: IMP dehydrogenase / GMP reductase domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01240
name:
  Protein Domains (SMART).STRING_v12.0_585425_STRINGid_SM01240_IMP_dehydrogenase_/_GMP_reductase_domain


id: SM01247
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01247
name:
  Protein Domains (SMART).STRING_v12.0_585425_STRINGid_SM01247_The_cyanobacterial_clock_proteins_KaiA_and_KaiB_are_proposed_as_regulators_of_the_circadian_rhythm_in_cyanobacteria._The_overall_fold_of_the_KaiA_monomer_is_that_of_a_four-helix_bundle,_which_forms_a_dimer_in_the_known_structure_(PMID:15071498).

description:
  The cyanobacterial clock proteins KaiA and KaiB are proposed as regulators of the circadian rhythm in cyanobacteria. The overall fold of the KaiA monomer is that of a four-helix bundle, which forms a dimer in the known structure (PMID:15071498).


id: SM01248
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01248
name:
  Protein Domains (SMART).STRING_v12.0_585425_STRINGid_SM01248_The_cyanobacterial_clock_proteins_KaiA_and_KaiB_are_proposed_as_regulators_of_the_circadian_rhythm_in_cyanobacteria._Mutations_in_both_proteins_have_been_reported_to_alter_or_abolish_circadian_rhythmicity._KaiB_adopts_an_alpha-beta_meander_motif_and_...

description:
  The cyanobacterial clock proteins KaiA and KaiB are proposed as regulators of the circadian rhythm in cyanobacteria. Mutations in both proteins have been reported to alter or abolish circadian rhythmicity. KaiB adopts an alpha-beta meander motif and ...


id: SM01329
description: Isocitrate/isopropylmalate dehydrogenase
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01329
name:
  Protein Domains (SMART).STRING_v12.0_585425_STRINGid_SM01329_Isocitrate/isopropylmalate_dehydrogenase


id: SM01350
description: 6-phosphogluconate dehydrogenase, C-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01350
name:
  Protein Domains (SMART).STRING_v12.0_585425_STRINGid_SM01350_6-phosphogluconate_dehydrogenase,_C-terminal_domain


id: SM01382
description: Ribosomal Proteins L2, C-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01382
name:
  Protein Domains (SMART).STRING_v12.0_585425_STRINGid_SM01382_Ribosomal_Proteins_L2,_C-terminal_domain


id: SM01383
description: Ribosomal Proteins L2, RNA binding domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01383
name:
  Protein Domains (SMART).STRING_v12.0_585425_STRINGid_SM01383_Ribosomal_Proteins_L2,_RNA_binding_domain


id: SM01390
description: Ribosomal protein S4/S9 N-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01390
name:
  Protein Domains (SMART).STRING_v12.0_585425_STRINGid_SM01390_Ribosomal_protein_S4/S9_N-terminal_domain


id: SM01400
description: N-terminal domain of ribose phosphate pyrophosphokinase
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01400
name:
  Protein Domains (SMART).STRING_v12.0_585425_STRINGid_SM01400_N-terminal_domain_of_ribose_phosphate_pyrophosphokinase


