# geneInfo

ensembl_gene_id: GCA_002104455_00032
symbol: merP
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in mercury resistance. Acts as a mercury scavenger that specifically binds to a mercuric ion in the periplasm and probably passes it to the cytoplasmic mercuric reductase MerA via the mercuric transport protein MerT.


ensembl_gene_id: GCA_002104455_00050
symbol: rraB
gene_biotype: protein_coding
description:
  Unannotated protein; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.


ensembl_gene_id: GCA_002104455_00067
symbol: ccmE
gene_biotype: protein_coding
description:
  Unannotated protein; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family.


ensembl_gene_id: GCA_002104455_00068
symbol: GCA_002104455_00068
gene_biotype: protein_coding
description:
  Unannotated protein; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmD/CycX/HelD family.


ensembl_gene_id: GCA_002104455_00069
symbol: ccmC
gene_biotype: protein_coding
description:
  Unannotated protein; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family.


ensembl_gene_id: GCA_002104455_00070
symbol: GCA_002104455_00070
gene_biotype: protein_coding
description:
  Unannotated protein; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family.


ensembl_gene_id: GCA_002104455_00071
symbol: ccmA
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.


ensembl_gene_id: GCA_002104455_00073
symbol: hemH
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.


ensembl_gene_id: GCA_002104455_00075
symbol: valS
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.


ensembl_gene_id: GCA_002104455_00077
symbol: pepA
gene_biotype: protein_coding
description:
  Unannotated protein; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.


ensembl_gene_id: GCA_002104455_00089
symbol: thiG
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.


ensembl_gene_id: GCA_002104455_00092
symbol: thiC
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.


ensembl_gene_id: GCA_002104455_00110
symbol: glyA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.


ensembl_gene_id: GCA_002104455_00111
symbol: nrdR
gene_biotype: protein_coding
description:
  Unannotated protein; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.


ensembl_gene_id: GCA_002104455_00112
symbol: GCA_002104455_00112
gene_biotype: protein_coding
description:
  Unannotated protein; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.


ensembl_gene_id: GCA_002104455_00114
symbol: ribB
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.


ensembl_gene_id: GCA_002104455_00115
symbol: dxs
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.


ensembl_gene_id: GCA_002104455_00117
symbol: xseB
gene_biotype: protein_coding
description:
  Unannotated protein; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.


ensembl_gene_id: GCA_002104455_00120
symbol: thiI
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.


ensembl_gene_id: GCA_002104455_00132
symbol: ffh
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components; Belongs to t [...]


ensembl_gene_id: GCA_002104455_00135
symbol: rimM
gene_biotype: protein_coding
description:
  Unannotated protein; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family.


ensembl_gene_id: GCA_002104455_00136
symbol: trmD
gene_biotype: protein_coding
description:
  Unannotated protein; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.


ensembl_gene_id: GCA_002104455_00137
symbol: rplS
gene_biotype: protein_coding
description:
  Unannotated protein; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.


ensembl_gene_id: GCA_002104455_00140
symbol: acsA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.


ensembl_gene_id: GCA_002104455_00141
symbol: GCA_002104455_00141
gene_biotype: protein_coding
description:
  Unannotated protein; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP).


ensembl_gene_id: GCA_002104455_00145
symbol: GCA_002104455_00145
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.


ensembl_gene_id: GCA_002104455_00161
symbol: msrP
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) [...]


ensembl_gene_id: GCA_002104455_00162
symbol: msrQ
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the  [...]


ensembl_gene_id: GCA_002104455_00169
symbol: glcB
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.


ensembl_gene_id: GCA_002104455_00176
symbol: GCA_002104455_00176
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.


ensembl_gene_id: GCA_002104455_00179
symbol: GCA_002104455_00179
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.


ensembl_gene_id: GCA_002104455_00187
symbol: GCA_002104455_00187
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P- ring assembly; Belongs to the FlgA family.


ensembl_gene_id: GCA_002104455_00190
symbol: GCA_002104455_00190
gene_biotype: protein_coding
description:
  Unannotated protein; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.


ensembl_gene_id: GCA_002104455_00196
symbol: flgH
gene_biotype: protein_coding
description:
  Unannotated protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.


ensembl_gene_id: GCA_002104455_00201
symbol: GCA_002104455_00201
gene_biotype: protein_coding
description:
  Unannotated protein; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.


ensembl_gene_id: GCA_002104455_00204
symbol: GCA_002104455_00204
gene_biotype: protein_coding
description:
  Unannotated protein; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.


ensembl_gene_id: GCA_002104455_00220
symbol: GCA_002104455_00220
gene_biotype: protein_coding
description:
  Unannotated protein; The M ring may be actively involved in energy transduction. Belongs to the FliF family.


ensembl_gene_id: GCA_002104455_00221
symbol: GCA_002104455_00221
gene_biotype: protein_coding
description:
  Unannotated protein; FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.


ensembl_gene_id: GCA_002104455_00226
symbol: GCA_002104455_00226
gene_biotype: protein_coding
description:
  Unannotated protein; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.


ensembl_gene_id: GCA_002104455_00227
symbol: GCA_002104455_00227
gene_biotype: protein_coding
description:
  Unannotated protein; FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.


ensembl_gene_id: GCA_002104455_00228
symbol: GCA_002104455_00228
gene_biotype: protein_coding
description:
  Unannotated protein; FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliN/MopA/SpaO family.


ensembl_gene_id: GCA_002104455_00230
symbol: fliP
gene_biotype: protein_coding
description:
  Unannotated protein; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family.


ensembl_gene_id: GCA_002104455_00233
symbol: flhB
gene_biotype: protein_coding
description:
  Unannotated protein; Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the type III secretion exporter family.


ensembl_gene_id: GCA_002104455_00234
symbol: flhA
gene_biotype: protein_coding
description:
  Unannotated protein; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.


ensembl_gene_id: GCA_002104455_00237
symbol: fliA
gene_biotype: protein_coding
description:
  Unannotated protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily.


ensembl_gene_id: GCA_002104455_00239
symbol: GCA_002104455_00239
gene_biotype: protein_coding
description:
  Unannotated protein; Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).


ensembl_gene_id: GCA_002104455_00241
symbol: cheB
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.


ensembl_gene_id: GCA_002104455_00250
symbol: ribH
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family.


ensembl_gene_id: GCA_002104455_00251
symbol: nusB
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.


ensembl_gene_id: GCA_002104455_00252
symbol: thiL
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.


ensembl_gene_id: GCA_002104455_00253
symbol: GCA_002104455_00253
gene_biotype: protein_coding
description:
  Unannotated protein; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).


ensembl_gene_id: GCA_002104455_00255
symbol: rpiA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.


ensembl_gene_id: GCA_002104455_00262
symbol: wecA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP-C55). Belongs to the glycosyltransferase 4 family. WecA subfamily.


ensembl_gene_id: GCA_002104455_00283
symbol: GCA_002104455_00283
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.


ensembl_gene_id: GCA_002104455_00285
symbol: GCA_002104455_00285
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.


ensembl_gene_id: GCA_002104455_00286
symbol: GCA_002104455_00286
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family.


ensembl_gene_id: GCA_002104455_00287
symbol: GCA_002104455_00287
gene_biotype: protein_coding
description:
  Unannotated protein; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.


ensembl_gene_id: GCA_002104455_00292
symbol: cysN
gene_biotype: protein_coding
description:
  Unannotated protein; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.


ensembl_gene_id: GCA_002104455_00298
symbol: GCA_002104455_00298
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: GCA_002104455_00307
symbol: fadI
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.


ensembl_gene_id: GCA_002104455_00308
symbol: GCA_002104455_00308
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities. Belongs to the enoyl-CoA hydratase/isomerase family.  In the central section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.


ensembl_gene_id: GCA_002104455_00316
symbol: prmB
gene_biotype: protein_coding
description:
  Unannotated protein; Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue; Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.


ensembl_gene_id: GCA_002104455_00317
symbol: aroC
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.


ensembl_gene_id: GCA_002104455_00318
symbol: lipA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.


ensembl_gene_id: GCA_002104455_00319
symbol: lipB
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.


ensembl_gene_id: GCA_002104455_00322
symbol: rlpA
gene_biotype: protein_coding
description:
  Unannotated protein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.


ensembl_gene_id: GCA_002104455_00323
symbol: mrdB
gene_biotype: protein_coding
description:
  Unannotated protein; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.


ensembl_gene_id: GCA_002104455_00324
symbol: mrdA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.


ensembl_gene_id: GCA_002104455_00325
symbol: rlmH
gene_biotype: protein_coding
description:
  Unannotated protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family.


ensembl_gene_id: GCA_002104455_00326
symbol: rsfS
gene_biotype: protein_coding
description:
  Unannotated protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.


ensembl_gene_id: GCA_002104455_00327
symbol: nadD
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).


ensembl_gene_id: GCA_002104455_00329
symbol: lptE
gene_biotype: protein_coding
description:
  Unannotated protein; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.


ensembl_gene_id: GCA_002104455_00333
symbol: nuoA
gene_biotype: protein_coding
description:
  Unannotated protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family.


ensembl_gene_id: GCA_002104455_00334
symbol: nuoB
gene_biotype: protein_coding
description:
  Unannotated protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: GCA_002104455_00335
symbol: nuoC
gene_biotype: protein_coding
description:
  Unannotated protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family.


ensembl_gene_id: GCA_002104455_00337
symbol: GCA_002104455_00337
gene_biotype: protein_coding
description:
  Unannotated protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family.


ensembl_gene_id: GCA_002104455_00339
symbol: nuoH
gene_biotype: protein_coding
description:
  Unannotated protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.


ensembl_gene_id: GCA_002104455_00341
symbol: GCA_002104455_00341
gene_biotype: protein_coding
description:
  Unannotated protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: GCA_002104455_00342
symbol: nuoK
gene_biotype: protein_coding
description:
  Unannotated protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family.


ensembl_gene_id: GCA_002104455_00345
symbol: nuoN
gene_biotype: protein_coding
description:
  Unannotated protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family.


ensembl_gene_id: GCA_002104455_00346
symbol: deaD
gene_biotype: protein_coding
description:
  Unannotated protein; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.


ensembl_gene_id: GCA_002104455_00353
symbol: trmJ
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.


ensembl_gene_id: GCA_002104455_00355
symbol: GCA_002104455_00355
gene_biotype: protein_coding
description:
  Unannotated protein; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.


ensembl_gene_id: GCA_002104455_00356
symbol: iscS
gene_biotype: protein_coding
description:
  Unannotated protein; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.


ensembl_gene_id: GCA_002104455_00357
symbol: GCA_002104455_00357
gene_biotype: protein_coding
description:
  Unannotated protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.


ensembl_gene_id: GCA_002104455_00358
symbol: GCA_002104455_00358
gene_biotype: protein_coding
description:
  Unannotated protein; Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system; Belongs to the HesB/IscA family.


ensembl_gene_id: GCA_002104455_00359
symbol: hscB
gene_biotype: protein_coding
description:
  Unannotated protein; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family.


ensembl_gene_id: GCA_002104455_00360
symbol: hscA
gene_biotype: protein_coding
description:
  Unannotated protein; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.


ensembl_gene_id: GCA_002104455_00390
symbol: fumC
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.


ensembl_gene_id: GCA_002104455_00394
symbol: smpB
gene_biotype: protein_coding
description:
  Unannotated protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to  [...]


ensembl_gene_id: GCA_002104455_00397
symbol: bamE
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: GCA_002104455_00399
symbol: nadK
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.


ensembl_gene_id: GCA_002104455_00400
symbol: grpE
gene_biotype: protein_coding
description:
  Unannotated protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depe [...]


ensembl_gene_id: GCA_002104455_00402
symbol: dnaJ
gene_biotype: protein_coding
description:
  Unannotated protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK [...]


ensembl_gene_id: GCA_002104455_00410
symbol: nhaA
gene_biotype: protein_coding
description:
  Unannotated protein; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.


ensembl_gene_id: GCA_002104455_00414
symbol: mnmC
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family.


ensembl_gene_id: GCA_002104455_00416
symbol: pdxB
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate.


ensembl_gene_id: GCA_002104455_00417
symbol: asd
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.


ensembl_gene_id: GCA_002104455_00419
symbol: truA
gene_biotype: protein_coding
description:
  Unannotated protein; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.


ensembl_gene_id: GCA_002104455_00420
symbol: accD
gene_biotype: protein_coding
description:
  Unannotated protein; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.


ensembl_gene_id: GCA_002104455_00424
symbol: purF
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.


ensembl_gene_id: GCA_002104455_00430
symbol: lnt
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily.


ensembl_gene_id: GCA_002104455_00435
symbol: lpxH
gene_biotype: protein_coding
description:
  Unannotated protein; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: GCA_002104455_00436
symbol: GCA_002104455_00436
gene_biotype: protein_coding
description:
  Unannotated protein; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.


ensembl_gene_id: GCA_002104455_00438
symbol: folD
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.


ensembl_gene_id: GCA_002104455_00443
symbol: tig
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.


ensembl_gene_id: GCA_002104455_00444
symbol: clpP
gene_biotype: protein_coding
description:
  Unannotated protein; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.


ensembl_gene_id: GCA_002104455_00445
symbol: clpX
gene_biotype: protein_coding
description:
  Unannotated protein; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.


ensembl_gene_id: GCA_002104455_00446
symbol: lon
gene_biotype: protein_coding
description:
  Unannotated protein; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.


ensembl_gene_id: GCA_002104455_00447
symbol: GCA_002104455_00447
gene_biotype: protein_coding
description:
  Unannotated protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.


ensembl_gene_id: GCA_002104455_00486
symbol: GCA_002104455_00486
gene_biotype: protein_coding
description:
  Unannotated protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.


ensembl_gene_id: GCA_002104455_00489
symbol: apt
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.


ensembl_gene_id: GCA_002104455_00490
symbol: dnaX
gene_biotype: protein_coding
description:
  Unannotated protein; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.


ensembl_gene_id: GCA_002104455_00491
symbol: GCA_002104455_00491
gene_biotype: protein_coding
description:
  Unannotated protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.


ensembl_gene_id: GCA_002104455_00492
symbol: GCA_002104455_00492
gene_biotype: protein_coding
description:
  Unannotated protein; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: GCA_002104455_00495
symbol: fabH
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.


ensembl_gene_id: GCA_002104455_00500
symbol: dusC
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs. Belongs to the Dus family. DusC subfamily.


ensembl_gene_id: GCA_002104455_00505
symbol: kynA
gene_biotype: protein_coding
description:
  Unannotated protein; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.


ensembl_gene_id: GCA_002104455_00506
symbol: kmo
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily.


ensembl_gene_id: GCA_002104455_00507
symbol: kynU
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively.


ensembl_gene_id: GCA_002104455_00510
symbol: nbaC
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.


ensembl_gene_id: GCA_002104455_00516
symbol: GCA_002104455_00516
gene_biotype: protein_coding
description:
  Unannotated protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.


ensembl_gene_id: GCA_002104455_00527
symbol: ybeY
gene_biotype: protein_coding
description:
  Unannotated protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.


ensembl_gene_id: GCA_002104455_00529
symbol: miaB
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.


ensembl_gene_id: GCA_002104455_00539
symbol: ychF
gene_biotype: protein_coding
description:
  Unannotated protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.


ensembl_gene_id: GCA_002104455_00540
symbol: pth
gene_biotype: protein_coding
description:
  Unannotated protein; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.


ensembl_gene_id: GCA_002104455_00541
symbol: rplY
gene_biotype: protein_coding
description:
  Unannotated protein; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.


ensembl_gene_id: GCA_002104455_00544
symbol: prs
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.


ensembl_gene_id: GCA_002104455_00545
symbol: ispE
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.


ensembl_gene_id: GCA_002104455_00546
symbol: GCA_002104455_00546
gene_biotype: protein_coding
description:
  Unannotated protein; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.


ensembl_gene_id: GCA_002104455_00547
symbol: hemA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).


ensembl_gene_id: GCA_002104455_00548
symbol: prfA
gene_biotype: protein_coding
description:
  Unannotated protein; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.


ensembl_gene_id: GCA_002104455_00549
symbol: prmC
gene_biotype: protein_coding
description:
  Unannotated protein; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.


ensembl_gene_id: GCA_002104455_00557
symbol: topA
gene_biotype: protein_coding
description:
  Unannotated protein; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]


ensembl_gene_id: GCA_002104455_00565
symbol: GCA_002104455_00565
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.


ensembl_gene_id: GCA_002104455_00587
symbol: GCA_002104455_00587
gene_biotype: protein_coding
description:
  Unannotated protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: GCA_002104455_00593
symbol: GCA_002104455_00593
gene_biotype: protein_coding
description:
  Unannotated protein; Required for the activity of the bacterial periplasmic transport system of putrescine; Belongs to the bacterial solute-binding protein PotD/PotF family.


ensembl_gene_id: GCA_002104455_00594
symbol: potA
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.


ensembl_gene_id: GCA_002104455_00603
symbol: metAS
gene_biotype: protein_coding
description:
  Unannotated protein; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine; Belongs to the MetA family.


ensembl_gene_id: GCA_002104455_00604
symbol: GCA_002104455_00604
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.


ensembl_gene_id: GCA_002104455_00605
symbol: GCA_002104455_00605
gene_biotype: protein_coding
description:
  Unannotated protein; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.


ensembl_gene_id: GCA_002104455_00612
symbol: prfC
gene_biotype: protein_coding
description:
  Unannotated protein; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.


ensembl_gene_id: GCA_002104455_00613
symbol: napF
gene_biotype: protein_coding
description:
  Unannotated protein; Could be involved in the maturation of NapA, the catalytic subunit of the periplasmic nitrate reductase, before its export into the periplasm; Belongs to the NapF family.


ensembl_gene_id: GCA_002104455_00616
symbol: napA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.


ensembl_gene_id: GCA_002104455_00617
symbol: GCA_002104455_00617
gene_biotype: protein_coding
description:
  Unannotated protein; Electron transfer subunit of the periplasmic nitrate reductase complex NapAB; Belongs to the NapB family.


ensembl_gene_id: GCA_002104455_00622
symbol: aceK
gene_biotype: protein_coding
description:
  Unannotated protein; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.


ensembl_gene_id: GCA_002104455_00623
symbol: queA
gene_biotype: protein_coding
description:
  Unannotated protein; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).


ensembl_gene_id: GCA_002104455_00624
symbol: tgt
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  [...]


ensembl_gene_id: GCA_002104455_00625
symbol: yajC
gene_biotype: protein_coding
description:
  Unannotated protein; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.


ensembl_gene_id: GCA_002104455_00626
symbol: secD
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.


ensembl_gene_id: GCA_002104455_00628
symbol: GCA_002104455_00628
gene_biotype: protein_coding
description:
  Unannotated protein; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family.


ensembl_gene_id: GCA_002104455_00635
symbol: GCA_002104455_00635
gene_biotype: protein_coding
description:
  Unannotated protein; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family.


ensembl_gene_id: GCA_002104455_00645
symbol: GCA_002104455_00645
gene_biotype: protein_coding
description:
  Unannotated protein; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.


ensembl_gene_id: GCA_002104455_00646
symbol: GCA_002104455_00646
gene_biotype: protein_coding
description:
  Unannotated protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: GCA_002104455_00650
symbol: lolD
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner.


ensembl_gene_id: GCA_002104455_00654
symbol: msbA
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.


ensembl_gene_id: GCA_002104455_00655
symbol: lpxK
gene_biotype: protein_coding
description:
  Unannotated protein; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).


ensembl_gene_id: GCA_002104455_00657
symbol: kdsB
gene_biotype: protein_coding
description:
  Unannotated protein; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.


ensembl_gene_id: GCA_002104455_00679
symbol: murJ
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.


ensembl_gene_id: GCA_002104455_00681
symbol: ileS
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.


ensembl_gene_id: GCA_002104455_00682
symbol: lspA
gene_biotype: protein_coding
description:
  Unannotated protein; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.


ensembl_gene_id: GCA_002104455_00684
symbol: ispH
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.


ensembl_gene_id: GCA_002104455_00693
symbol: nadE
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family.


ensembl_gene_id: GCA_002104455_00697
symbol: GCA_002104455_00697
gene_biotype: protein_coding
description:
  Unannotated protein; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.


ensembl_gene_id: GCA_002104455_00699
symbol: clpB
gene_biotype: protein_coding
description:
  Unannotated protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.


ensembl_gene_id: GCA_002104455_00718
symbol: dapF
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.


ensembl_gene_id: GCA_002104455_00719
symbol: lysA
gene_biotype: protein_coding
description:
  Unannotated protein; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.


ensembl_gene_id: GCA_002104455_00721
symbol: cyaY
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.


ensembl_gene_id: GCA_002104455_00722
symbol: hemC
gene_biotype: protein_coding
description:
  Unannotated protein; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.


ensembl_gene_id: GCA_002104455_00727
symbol: ubiD
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.


ensembl_gene_id: GCA_002104455_00729
symbol: rho
gene_biotype: protein_coding
description:
  Unannotated protein; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.


ensembl_gene_id: GCA_002104455_00731
symbol: rhlB
gene_biotype: protein_coding
description:
  Unannotated protein; DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. Belongs to the DEAD box helicase family. RhlB subfamily.


ensembl_gene_id: GCA_002104455_00737
symbol: tatC
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.


ensembl_gene_id: GCA_002104455_00738
symbol: tatB
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.


ensembl_gene_id: GCA_002104455_00739
symbol: tatA
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.


ensembl_gene_id: GCA_002104455_00743
symbol: rpoH
gene_biotype: protein_coding
description:
  Unannotated protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.


ensembl_gene_id: GCA_002104455_00744
symbol: GCA_002104455_00744
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.


ensembl_gene_id: GCA_002104455_00746
symbol: ftsY
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.


ensembl_gene_id: GCA_002104455_00747
symbol: GCA_002104455_00747
gene_biotype: protein_coding
description:
  Unannotated protein; Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle; Belongs to the methyltransferase superfamily. RsmD family.


ensembl_gene_id: GCA_002104455_00748
symbol: speE
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.


ensembl_gene_id: GCA_002104455_00751
symbol: GCA_002104455_00751
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the biosynthesis of agmatine from arginine. Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.


ensembl_gene_id: GCA_002104455_00759
symbol: GCA_002104455_00759
gene_biotype: protein_coding
description:
  Unannotated protein; Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities. Belongs to the phospholipase A1 family.


ensembl_gene_id: GCA_002104455_00772
symbol: GCA_002104455_00772
gene_biotype: protein_coding
description:
  Unannotated protein; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. Belongs to the peptidase M17 family.


ensembl_gene_id: GCA_002104455_00785
symbol: glmS
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.


ensembl_gene_id: GCA_002104455_00787
symbol: glmU
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.


ensembl_gene_id: GCA_002104455_00796
symbol: atpC
gene_biotype: protein_coding
description:
  Unannotated protein; Produces ATP from ADP in the presence of a proton gradient across the membrane.


ensembl_gene_id: GCA_002104455_00797
symbol: atpD
gene_biotype: protein_coding
description:
  Unannotated protein; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.


ensembl_gene_id: GCA_002104455_00798
symbol: atpG
gene_biotype: protein_coding
description:
  Unannotated protein; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.


ensembl_gene_id: GCA_002104455_00799
symbol: atpA
gene_biotype: protein_coding
description:
  Unannotated protein; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.


ensembl_gene_id: GCA_002104455_00800
symbol: atpH
gene_biotype: protein_coding
description:
  Unannotated protein; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.


ensembl_gene_id: GCA_002104455_00801
symbol: atpF
gene_biotype: protein_coding
description:
  Unannotated protein; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family.


ensembl_gene_id: GCA_002104455_00803
symbol: atpB
gene_biotype: protein_coding
description:
  Unannotated protein; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family.


ensembl_gene_id: GCA_002104455_00807
symbol: rsmG
gene_biotype: protein_coding
description:
  Unannotated protein; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.


ensembl_gene_id: GCA_002104455_00808
symbol: mnmG
gene_biotype: protein_coding
description:
  Unannotated protein; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family.


ensembl_gene_id: GCA_002104455_00812
symbol: mnmE
gene_biotype: protein_coding
description:
  Unannotated protein; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.


ensembl_gene_id: GCA_002104455_00813
symbol: yidC
gene_biotype: protein_coding
description:
  Unannotated protein; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.


ensembl_gene_id: GCA_002104455_00814
symbol: GCA_002104455_00814
gene_biotype: protein_coding
description:
  Unannotated protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family.


ensembl_gene_id: GCA_002104455_00815
symbol: rnpA
gene_biotype: protein_coding
description:
  Unannotated protein; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.


ensembl_gene_id: GCA_002104455_00817
symbol: dnaA
gene_biotype: protein_coding
description:
  Unannotated protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.


ensembl_gene_id: GCA_002104455_00818
symbol: GCA_002104455_00818
gene_biotype: protein_coding
description:
  Unannotated protein; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication  [...]


ensembl_gene_id: GCA_002104455_00819
symbol: recF
gene_biotype: protein_coding
description:
  Unannotated protein; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.


ensembl_gene_id: GCA_002104455_00820
symbol: gyrB
gene_biotype: protein_coding
description:
  Unannotated protein; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.


ensembl_gene_id: GCA_002104455_00823
symbol: tusA
gene_biotype: protein_coding
description:
  Unannotated protein; Sulfur carrier protein which probably makes part of a sulfur- relay system; Belongs to the sulfur carrier protein TusA family.


ensembl_gene_id: GCA_002104455_00827
symbol: GCA_002104455_00827
gene_biotype: protein_coding
description:
  Unannotated protein; Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA; Belongs to the TrkH potassium transport family.


ensembl_gene_id: GCA_002104455_00830
symbol: fmt
gene_biotype: protein_coding
description:
  Unannotated protein; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.


ensembl_gene_id: GCA_002104455_00831
symbol: def
gene_biotype: protein_coding
description:
  Unannotated protein; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.


ensembl_gene_id: GCA_002104455_00836
symbol: purK
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).


ensembl_gene_id: GCA_002104455_00837
symbol: purE
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).


ensembl_gene_id: GCA_002104455_00839
symbol: tsaC
gene_biotype: protein_coding
description:
  Unannotated protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.


ensembl_gene_id: GCA_002104455_00840
symbol: hemF
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX.


ensembl_gene_id: GCA_002104455_00842
symbol: aroE
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).


ensembl_gene_id: GCA_002104455_00845
symbol: ttcA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.


ensembl_gene_id: GCA_002104455_00851
symbol: ihfA
gene_biotype: protein_coding
description:
  Unannotated protein; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.


ensembl_gene_id: GCA_002104455_00852
symbol: pheT
gene_biotype: protein_coding
description:
  Unannotated protein; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.


ensembl_gene_id: GCA_002104455_00853
symbol: pheS
gene_biotype: protein_coding
description:
  Unannotated protein; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.


ensembl_gene_id: GCA_002104455_00855
symbol: rplT
gene_biotype: protein_coding
description:
  Unannotated protein; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.


ensembl_gene_id: GCA_002104455_00857
symbol: infC
gene_biotype: protein_coding
description:
  Unannotated protein; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.


ensembl_gene_id: GCA_002104455_00858
symbol: thrS
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).


ensembl_gene_id: GCA_002104455_00872
symbol: GCA_002104455_00872
gene_biotype: protein_coding
description:
  Unannotated protein; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.


ensembl_gene_id: GCA_002104455_00878
symbol: GCA_002104455_00878
gene_biotype: protein_coding
description:
  Unannotated protein; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family.


ensembl_gene_id: GCA_002104455_00880
symbol: GCA_002104455_00880
gene_biotype: protein_coding
description:
  Unannotated protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.


ensembl_gene_id: GCA_002104455_00881
symbol: metG
gene_biotype: protein_coding
description:
  Unannotated protein; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.


ensembl_gene_id: GCA_002104455_00893
symbol: sbcD
gene_biotype: protein_coding
description:
  Unannotated protein; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.


ensembl_gene_id: GCA_002104455_00949
symbol: upp
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.


ensembl_gene_id: GCA_002104455_00951
symbol: ftsB
gene_biotype: protein_coding
description:
  Unannotated protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.


ensembl_gene_id: GCA_002104455_00952
symbol: ispD
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).


ensembl_gene_id: GCA_002104455_00953
symbol: ispF
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).


ensembl_gene_id: GCA_002104455_00954
symbol: truD
gene_biotype: protein_coding
description:
  Unannotated protein; Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family.


ensembl_gene_id: GCA_002104455_00955
symbol: surE
gene_biotype: protein_coding
description:
  Unannotated protein; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.


ensembl_gene_id: GCA_002104455_00956
symbol: pcm
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.


ensembl_gene_id: GCA_002104455_00959
symbol: rpoS
gene_biotype: protein_coding
description:
  Unannotated protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.


ensembl_gene_id: GCA_002104455_00960
symbol: mutS
gene_biotype: protein_coding
description:
  Unannotated protein; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.


ensembl_gene_id: GCA_002104455_00961
symbol: recA
gene_biotype: protein_coding
description:
  Unannotated protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.


ensembl_gene_id: GCA_002104455_00978
symbol: mfd
gene_biotype: protein_coding
description:
  Unannotated protein; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.


ensembl_gene_id: GCA_002104455_01003
symbol: GCA_002104455_01003
gene_biotype: protein_coding
description:
  Unannotated protein; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family.


ensembl_gene_id: GCA_002104455_01007
symbol: seqA
gene_biotype: protein_coding
description:
  Unannotated protein; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated.


ensembl_gene_id: GCA_002104455_01011
symbol: GCA_002104455_01011
gene_biotype: protein_coding
description:
  Unannotated protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.


ensembl_gene_id: GCA_002104455_01015
symbol: astE
gene_biotype: protein_coding
description:
  Unannotated protein; Transforms N(2)-succinylglutamate into succinate and glutamate; Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.


ensembl_gene_id: GCA_002104455_01016
symbol: GCA_002104455_01016
gene_biotype: protein_coding
description:
  Unannotated protein; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).


ensembl_gene_id: GCA_002104455_01023
symbol: cmoB
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L- methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5- carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.


ensembl_gene_id: GCA_002104455_01024
symbol: cmoA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).


ensembl_gene_id: GCA_002104455_01026
symbol: aspS
gene_biotype: protein_coding
description:
  Unannotated protein; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.


ensembl_gene_id: GCA_002104455_01027
symbol: ruvC
gene_biotype: protein_coding
description:
  Unannotated protein; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.


ensembl_gene_id: GCA_002104455_01028
symbol: ruvA
gene_biotype: protein_coding
description:
  Unannotated protein; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.


ensembl_gene_id: GCA_002104455_01029
symbol: ruvB
gene_biotype: protein_coding
description:
  Unannotated protein; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.


ensembl_gene_id: GCA_002104455_01031
symbol: tolQ
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: GCA_002104455_01036
symbol: cpoB
gene_biotype: protein_coding
description:
  Unannotated protein; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family.


ensembl_gene_id: GCA_002104455_01040
symbol: nadA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate; Belongs to the quinolinate synthase A family. Type 1 subfamily.


ensembl_gene_id: GCA_002104455_01045
symbol: GCA_002104455_01045
gene_biotype: protein_coding
description:
  Unannotated protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.


ensembl_gene_id: GCA_002104455_01054
symbol: uvrA
gene_biotype: protein_coding
description:
  Unannotated protein; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.


ensembl_gene_id: GCA_002104455_01056
symbol: speE-2
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine; Belongs to the spermidine/spermine synthase family.


ensembl_gene_id: GCA_002104455_01064
symbol: ubiX
gene_biotype: protein_coding
description:
  Unannotated protein; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family.


ensembl_gene_id: GCA_002104455_01065
symbol: mpl
gene_biotype: protein_coding
description:
  Unannotated protein; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily.


ensembl_gene_id: GCA_002104455_01067
symbol: GCA_002104455_01067
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.


ensembl_gene_id: GCA_002104455_01073
symbol: argD
gene_biotype: protein_coding
description:
  Unannotated protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.


ensembl_gene_id: GCA_002104455_01075
symbol: astD
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.


ensembl_gene_id: GCA_002104455_01083
symbol: srkA
gene_biotype: protein_coding
description:
  Unannotated protein; A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.


ensembl_gene_id: GCA_002104455_01090
symbol: purU
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).


ensembl_gene_id: GCA_002104455_01099
symbol: proA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.


ensembl_gene_id: GCA_002104455_01100
symbol: proB
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.


ensembl_gene_id: GCA_002104455_01105
symbol: ubiA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.


ensembl_gene_id: GCA_002104455_01106
symbol: ubiC
gene_biotype: protein_coding
description:
  Unannotated protein; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family.


ensembl_gene_id: GCA_002104455_01109
symbol: glpE
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.


ensembl_gene_id: GCA_002104455_01110
symbol: tdh
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family.


ensembl_gene_id: GCA_002104455_01113
symbol: GCA_002104455_01113
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.


ensembl_gene_id: GCA_002104455_01117
symbol: kdkA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the ATP-dependent phosphorylation of the 3-deoxy-D- manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position; Belongs to the protein kinase superfamily. KdkA/RfaP family.


ensembl_gene_id: GCA_002104455_01119
symbol: coaD
gene_biotype: protein_coding
description:
  Unannotated protein; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.


ensembl_gene_id: GCA_002104455_01120
symbol: mutM
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.


ensembl_gene_id: GCA_002104455_01130
symbol: GCA_002104455_01130
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.


ensembl_gene_id: GCA_002104455_01131
symbol: slmA
gene_biotype: protein_coding
description:
  Unannotated protein; Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.


ensembl_gene_id: GCA_002104455_01144
symbol: icmF
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.


ensembl_gene_id: GCA_002104455_01165
symbol: GCA_002104455_01165
gene_biotype: protein_coding
description:
  Unannotated protein; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.


ensembl_gene_id: GCA_002104455_01166
symbol: GCA_002104455_01166
gene_biotype: protein_coding
description:
  Unannotated protein; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the AlaDH/PNT family.


ensembl_gene_id: GCA_002104455_01171
symbol: rnd
gene_biotype: protein_coding
description:
  Unannotated protein; Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides; Belongs to the RNase D family.


ensembl_gene_id: GCA_002104455_01173
symbol: GCA_002104455_01173
gene_biotype: protein_coding
description:
  Unannotated protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.


ensembl_gene_id: GCA_002104455_01174
symbol: GCA_002104455_01174
gene_biotype: protein_coding
description:
  Unannotated protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.


ensembl_gene_id: GCA_002104455_01179
symbol: trpD
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).


ensembl_gene_id: GCA_002104455_01181
symbol: trpB
gene_biotype: protein_coding
description:
  Unannotated protein; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.


ensembl_gene_id: GCA_002104455_01182
symbol: trpA
gene_biotype: protein_coding
description:
  Unannotated protein; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.


ensembl_gene_id: GCA_002104455_01189
symbol: recR
gene_biotype: protein_coding
description:
  Unannotated protein; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.


ensembl_gene_id: GCA_002104455_01195
symbol: lgt
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.


ensembl_gene_id: GCA_002104455_01226
symbol: trmA
gene_biotype: protein_coding
description:
  Unannotated protein; Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).


ensembl_gene_id: GCA_002104455_01229
symbol: sthA
gene_biotype: protein_coding
description:
  Unannotated protein; Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.


ensembl_gene_id: GCA_002104455_01232
symbol: hemE
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.


ensembl_gene_id: GCA_002104455_01245
symbol: cysQ
gene_biotype: protein_coding
description:
  Unannotated protein; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family.


ensembl_gene_id: GCA_002104455_01250
symbol: GCA_002104455_01250
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.


ensembl_gene_id: GCA_002104455_01261
symbol: hslO
gene_biotype: protein_coding
description:
  Unannotated protein; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.


ensembl_gene_id: GCA_002104455_01273
symbol: dusA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily.


ensembl_gene_id: GCA_002104455_01279
symbol: GCA_002104455_01279
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.


ensembl_gene_id: GCA_002104455_01280
symbol: GCA_002104455_01280
gene_biotype: protein_coding
description:
  Unannotated protein; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily.


ensembl_gene_id: GCA_002104455_01285
symbol: priA
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.


ensembl_gene_id: GCA_002104455_01287
symbol: hslV
gene_biotype: protein_coding
description:
  Unannotated protein; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.


ensembl_gene_id: GCA_002104455_01288
symbol: hslU
gene_biotype: protein_coding
description:
  Unannotated protein; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.


ensembl_gene_id: GCA_002104455_01292
symbol: rraA
gene_biotype: protein_coding
description:
  Unannotated protein; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome.


ensembl_gene_id: GCA_002104455_01307
symbol: dtd
gene_biotype: protein_coding
description:
  Unannotated protein; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family.


ensembl_gene_id: GCA_002104455_01316
symbol: ntrC
gene_biotype: protein_coding
description:
  Unannotated protein; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.


ensembl_gene_id: GCA_002104455_01330
symbol: GCA_002104455_01330
gene_biotype: protein_coding
description:
  Unannotated protein; Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.


ensembl_gene_id: GCA_002104455_01377
symbol: GCA_002104455_01377
gene_biotype: protein_coding
description:
  Unannotated protein; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily.


ensembl_gene_id: GCA_002104455_01396
symbol: GCA_002104455_01396
gene_biotype: protein_coding
description:
  Unannotated protein; Subunit R is required for both nuclease and ATPase activities, but not for modification.


ensembl_gene_id: GCA_002104455_01416
symbol: fdhD
gene_biotype: protein_coding
description:
  Unannotated protein; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.


ensembl_gene_id: GCA_002104455_01435
symbol: galK
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily.


ensembl_gene_id: GCA_002104455_01461
symbol: uvrB
gene_biotype: protein_coding
description:
  Unannotated protein; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the [...]


ensembl_gene_id: GCA_002104455_01482
symbol: gcvP
gene_biotype: protein_coding
description:
  Unannotated protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.


ensembl_gene_id: GCA_002104455_01483
symbol: gcvH
gene_biotype: protein_coding
description:
  Unannotated protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.


ensembl_gene_id: GCA_002104455_01489
symbol: GCA_002104455_01489
gene_biotype: protein_coding
description:
  Unannotated protein; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.


ensembl_gene_id: GCA_002104455_01491
symbol: metK
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.


ensembl_gene_id: GCA_002104455_01494
symbol: GCA_002104455_01494
gene_biotype: protein_coding
description:
  Unannotated protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.


ensembl_gene_id: GCA_002104455_01497
symbol: GCA_002104455_01497
gene_biotype: protein_coding
description:
  Unannotated protein; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family.


ensembl_gene_id: GCA_002104455_01501
symbol: GCA_002104455_01501
gene_biotype: protein_coding
description:
  Unannotated protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.


ensembl_gene_id: GCA_002104455_01506
symbol: GCA_002104455_01506
gene_biotype: protein_coding
description:
  Unannotated protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.


ensembl_gene_id: GCA_002104455_01507
symbol: GCA_002104455_01507
gene_biotype: protein_coding
description:
  Unannotated protein; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.


ensembl_gene_id: GCA_002104455_01508
symbol: tadA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.


ensembl_gene_id: GCA_002104455_01510
symbol: mltF
gene_biotype: protein_coding
description:
  Unannotated protein; Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.


ensembl_gene_id: GCA_002104455_01511
symbol: purL
gene_biotype: protein_coding
description:
  Unannotated protein; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.


ensembl_gene_id: GCA_002104455_01518
symbol: dapA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).


ensembl_gene_id: GCA_002104455_01534
symbol: GCA_002104455_01534
gene_biotype: protein_coding
description:
  Unannotated protein; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.


ensembl_gene_id: GCA_002104455_01536
symbol: GCA_002104455_01536
gene_biotype: protein_coding
description:
  Unannotated protein; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.


ensembl_gene_id: GCA_002104455_01554
symbol: GCA_002104455_01554
gene_biotype: protein_coding
description:
  Unannotated protein; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.


ensembl_gene_id: GCA_002104455_01555
symbol: deoA
gene_biotype: protein_coding
description:
  Unannotated protein; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.


ensembl_gene_id: GCA_002104455_01557
symbol: GCA_002104455_01557
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate.


ensembl_gene_id: GCA_002104455_01560
symbol: deoB
gene_biotype: protein_coding
description:
  Unannotated protein; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family.


ensembl_gene_id: GCA_002104455_01563
symbol: GCA_002104455_01563
gene_biotype: protein_coding
description:
  Unannotated protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.


ensembl_gene_id: GCA_002104455_01564
symbol: GCA_002104455_01564
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.


ensembl_gene_id: GCA_002104455_01572
symbol: mnmA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.


ensembl_gene_id: GCA_002104455_01578
symbol: clpS
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family.


ensembl_gene_id: GCA_002104455_01580
symbol: infA
gene_biotype: protein_coding
description:
  Unannotated protein; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.


ensembl_gene_id: GCA_002104455_01581
symbol: bpt
gene_biotype: protein_coding
description:
  Unannotated protein; Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate. Belongs to the R-transferase family. Bpt subfamily.


ensembl_gene_id: GCA_002104455_01583
symbol: aat
gene_biotype: protein_coding
description:
  Unannotated protein; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.


ensembl_gene_id: GCA_002104455_01607
symbol: mntP
gene_biotype: protein_coding
description:
  Unannotated protein; Probably functions as a manganese efflux pump. Belongs to the MntP (TC 9.B.29) family.


ensembl_gene_id: GCA_002104455_01637
symbol: GCA_002104455_01637
gene_biotype: protein_coding
description:
  Unannotated protein; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.


ensembl_gene_id: GCA_002104455_01639
symbol: apaH
gene_biotype: protein_coding
description:
  Unannotated protein; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family.


ensembl_gene_id: GCA_002104455_01641
symbol: rsmA
gene_biotype: protein_coding
description:
  Unannotated protein; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.


ensembl_gene_id: GCA_002104455_01642
symbol: pdxA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).


ensembl_gene_id: GCA_002104455_01643
symbol: surA
gene_biotype: protein_coding
description:
  Unannotated protein; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.


ensembl_gene_id: GCA_002104455_01644
symbol: lptD
gene_biotype: protein_coding
description:
  Unannotated protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.


ensembl_gene_id: GCA_002104455_01647
symbol: djlA
gene_biotype: protein_coding
description:
  Unannotated protein; Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.


ensembl_gene_id: GCA_002104455_01662
symbol: rpoD
gene_biotype: protein_coding
description:
  Unannotated protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.


ensembl_gene_id: GCA_002104455_01663
symbol: dnaG
gene_biotype: protein_coding
description:
  Unannotated protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.


ensembl_gene_id: GCA_002104455_01666
symbol: tsaD
gene_biotype: protein_coding
description:
  Unannotated protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.


ensembl_gene_id: GCA_002104455_01667
symbol: plsY
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.


ensembl_gene_id: GCA_002104455_01668
symbol: GCA_002104455_01668
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.


ensembl_gene_id: GCA_002104455_01670
symbol: uppP
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.


ensembl_gene_id: GCA_002104455_01674
symbol: msrA
gene_biotype: protein_coding
description:
  Unannotated protein; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.


ensembl_gene_id: GCA_002104455_01676
symbol: rmf
gene_biotype: protein_coding
description:
  Unannotated protein; During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes); Belongs to the ribosome modulation factor family.


ensembl_gene_id: GCA_002104455_01678
symbol: GCA_002104455_01678
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Molybdate importer (TC 3.A.1.8) family.


ensembl_gene_id: GCA_002104455_01679
symbol: GCA_002104455_01679
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: GCA_002104455_01681
symbol: GCA_002104455_01681
gene_biotype: protein_coding
description:
  Unannotated protein; May be involved in the biosynthesis of molybdopterin. Belongs to the MoaB/Mog family.


ensembl_gene_id: GCA_002104455_01682
symbol: GCA_002104455_01682
gene_biotype: protein_coding
description:
  Unannotated protein; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family.


ensembl_gene_id: GCA_002104455_01683
symbol: moaA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.


ensembl_gene_id: GCA_002104455_01684
symbol: GCA_002104455_01684
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.


ensembl_gene_id: GCA_002104455_01693
symbol: thrB
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.


ensembl_gene_id: GCA_002104455_01695
symbol: ung
gene_biotype: protein_coding
description:
  Unannotated protein; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.


ensembl_gene_id: GCA_002104455_01703
symbol: ndk
gene_biotype: protein_coding
description:
  Unannotated protein; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.


ensembl_gene_id: GCA_002104455_01704
symbol: rlmN
gene_biotype: protein_coding
description:
  Unannotated protein; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family.


ensembl_gene_id: GCA_002104455_01707
symbol: ispG
gene_biotype: protein_coding
description:
  Unannotated protein; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family.


ensembl_gene_id: GCA_002104455_01711
symbol: der
gene_biotype: protein_coding
description:
  Unannotated protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.


ensembl_gene_id: GCA_002104455_01713
symbol: xseA
gene_biotype: protein_coding
description:
  Unannotated protein; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family.


ensembl_gene_id: GCA_002104455_01714
symbol: guaB
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.


ensembl_gene_id: GCA_002104455_01723
symbol: GCA_002104455_01723
gene_biotype: protein_coding
description:
  Unannotated protein; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degradi [...]


ensembl_gene_id: GCA_002104455_01726
symbol: lepA
gene_biotype: protein_coding
description:
  Unannotated protein; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.


ensembl_gene_id: GCA_002104455_01728
symbol: rnc
gene_biotype: protein_coding
description:
  Unannotated protein; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.


ensembl_gene_id: GCA_002104455_01729
symbol: era
gene_biotype: protein_coding
description:
  Unannotated protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.


ensembl_gene_id: GCA_002104455_01731
symbol: pdxJ
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.


ensembl_gene_id: GCA_002104455_01732
symbol: acpS
gene_biotype: protein_coding
description:
  Unannotated protein; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.


ensembl_gene_id: GCA_002104455_01736
symbol: rlmD
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.


ensembl_gene_id: GCA_002104455_01737
symbol: GCA_002104455_01737
gene_biotype: protein_coding
description:
  Unannotated protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.


ensembl_gene_id: GCA_002104455_01758
symbol: GCA_002104455_01758
gene_biotype: protein_coding
description:
  Unannotated protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.


ensembl_gene_id: GCA_002104455_01764
symbol: GCA_002104455_01764
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.


ensembl_gene_id: GCA_002104455_01780
symbol: mutH
gene_biotype: protein_coding
description:
  Unannotated protein; Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair. Belongs to the MutH family.


ensembl_gene_id: GCA_002104455_01781
symbol: rppH
gene_biotype: protein_coding
description:
  Unannotated protein; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily.


ensembl_gene_id: GCA_002104455_01784
symbol: thyA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.


ensembl_gene_id: GCA_002104455_01797
symbol: selO
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation). Belongs to the SELO family.


ensembl_gene_id: GCA_002104455_01801
symbol: pstB
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.


ensembl_gene_id: GCA_002104455_01809
symbol: cca
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 2 subfamily.


ensembl_gene_id: GCA_002104455_01811
symbol: leuD
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.


ensembl_gene_id: GCA_002104455_01812
symbol: leuC
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.


ensembl_gene_id: GCA_002104455_01813
symbol: leuB
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.


ensembl_gene_id: GCA_002104455_01814
symbol: leuA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.


ensembl_gene_id: GCA_002104455_01830
symbol: glnE
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) [...]


ensembl_gene_id: GCA_002104455_01832
symbol: lpxL
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A).


ensembl_gene_id: GCA_002104455_01833
symbol: hldE
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family.


ensembl_gene_id: GCA_002104455_01840
symbol: parE
gene_biotype: protein_coding
description:
  Unannotated protein; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily.


ensembl_gene_id: GCA_002104455_01857
symbol: parC
gene_biotype: protein_coding
description:
  Unannotated protein; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.


ensembl_gene_id: GCA_002104455_01861
symbol: tal
gene_biotype: protein_coding
description:
  Unannotated protein; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.


ensembl_gene_id: GCA_002104455_01866
symbol: srmB
gene_biotype: protein_coding
description:
  Unannotated protein; DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity; Belongs to the DEAD box helicase family. SrmB subfamily.


ensembl_gene_id: GCA_002104455_01871
symbol: prfB
gene_biotype: protein_coding
description:
  Unannotated protein; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.


ensembl_gene_id: GCA_002104455_01885
symbol: fabV
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon- carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP); Belongs to the TER reductase family.


ensembl_gene_id: GCA_002104455_01886
symbol: nqrA
gene_biotype: protein_coding
description:
  Unannotated protein; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.


ensembl_gene_id: GCA_002104455_01889
symbol: nqrD
gene_biotype: protein_coding
description:
  Unannotated protein; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol; Belongs to the NqrDE/RnfAE family.


ensembl_gene_id: GCA_002104455_01891
symbol: nqrF
gene_biotype: protein_coding
description:
  Unannotated protein; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.


ensembl_gene_id: GCA_002104455_01892
symbol: GCA_002104455_01892
gene_biotype: protein_coding
description:
  Unannotated protein; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. Belongs to the ApbE family.


ensembl_gene_id: GCA_002104455_01895
symbol: dinB
gene_biotype: protein_coding
description:
  Unannotated protein; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.


ensembl_gene_id: GCA_002104455_01900
symbol: ureG
gene_biotype: protein_coding
description:
  Unannotated protein; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.


ensembl_gene_id: GCA_002104455_01901
symbol: ureF
gene_biotype: protein_coding
description:
  Unannotated protein; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.


ensembl_gene_id: GCA_002104455_01902
symbol: ureE
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family.


ensembl_gene_id: GCA_002104455_01909
symbol: alaS
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.


ensembl_gene_id: GCA_002104455_01910
symbol: csrA
gene_biotype: protein_coding
description:
  Unannotated protein; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).


ensembl_gene_id: GCA_002104455_01917
symbol: GCA_002104455_01917
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation; Belongs to the GcdB/MmdB/OadB family.


ensembl_gene_id: GCA_002104455_01918
symbol: pdxH
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).


ensembl_gene_id: GCA_002104455_01920
symbol: tmcA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).


ensembl_gene_id: GCA_002104455_01930
symbol: pyrG
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.


ensembl_gene_id: GCA_002104455_01931
symbol: eno
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.


ensembl_gene_id: GCA_002104455_01937
symbol: engB
gene_biotype: protein_coding
description:
  Unannotated protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.


ensembl_gene_id: GCA_002104455_01983
symbol: purA
gene_biotype: protein_coding
description:
  Unannotated protein; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.


ensembl_gene_id: GCA_002104455_01985
symbol: GCA_002104455_01985
gene_biotype: protein_coding
description:
  Unannotated protein; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis.


ensembl_gene_id: GCA_002104455_01990
symbol: trpS
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: GCA_002104455_01994
symbol: GCA_002104455_01994
gene_biotype: protein_coding
description:
  Unannotated protein; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.


ensembl_gene_id: GCA_002104455_02024
symbol: GCA_002104455_02024
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.


ensembl_gene_id: GCA_002104455_02026
symbol: prmA
gene_biotype: protein_coding
description:
  Unannotated protein; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family.


ensembl_gene_id: GCA_002104455_02027
symbol: dusB
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily.


ensembl_gene_id: GCA_002104455_02028
symbol: GCA_002104455_02028
gene_biotype: protein_coding
description:
  Unannotated protein; Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters; Belongs to the transcriptional regulatory Fis family.


ensembl_gene_id: GCA_002104455_02043
symbol: greB
gene_biotype: protein_coding
description:
  Unannotated protein; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.


ensembl_gene_id: GCA_002104455_02051
symbol: rpoZ
gene_biotype: protein_coding
description:
  Unannotated protein; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.


ensembl_gene_id: GCA_002104455_02054
symbol: trmH
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.


ensembl_gene_id: GCA_002104455_02055
symbol: recG
gene_biotype: protein_coding
description:
  Unannotated protein; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily.


ensembl_gene_id: GCA_002104455_02056
symbol: ubiE
gene_biotype: protein_coding
description:
  Unannotated protein; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2).


ensembl_gene_id: GCA_002104455_02058
symbol: ubiB
gene_biotype: protein_coding
description:
  Unannotated protein; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. Belongs to the ABC1 family. UbiB subfamily.


ensembl_gene_id: GCA_002104455_02061
symbol: rep
gene_biotype: protein_coding
description:
  Unannotated protein; Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.


ensembl_gene_id: GCA_002104455_02065
symbol: ilvA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.


ensembl_gene_id: GCA_002104455_02067
symbol: ilvE
gene_biotype: protein_coding
description:
  Unannotated protein; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: GCA_002104455_02072
symbol: ilvC
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.


ensembl_gene_id: GCA_002104455_02105
symbol: rapA
gene_biotype: protein_coding
description:
  Unannotated protein; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily.


ensembl_gene_id: GCA_002104455_02116
symbol: GCA_002104455_02116
gene_biotype: protein_coding
description:
  Unannotated protein; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.


ensembl_gene_id: GCA_002104455_02120
symbol: rnt
gene_biotype: protein_coding
description:
  Unannotated protein; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.


ensembl_gene_id: GCA_002104455_02124
symbol: cysZ
gene_biotype: protein_coding
description:
  Unannotated protein; High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway; Belongs to the CysZ family.


ensembl_gene_id: GCA_002104455_02125
symbol: smc
gene_biotype: protein_coding
description:
  Unannotated protein; Required for chromosome condensation and partitioning. Belongs to the SMC family.


ensembl_gene_id: GCA_002104455_02126
symbol: zipA
gene_biotype: protein_coding
description:
  Unannotated protein; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.


ensembl_gene_id: GCA_002104455_02127
symbol: ligA
gene_biotype: protein_coding
description:
  Unannotated protein; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.


ensembl_gene_id: GCA_002104455_02139
symbol: dapB
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.


ensembl_gene_id: GCA_002104455_02142
symbol: greA
gene_biotype: protein_coding
description:
  Unannotated protein; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.


ensembl_gene_id: GCA_002104455_02145
symbol: rlmE
gene_biotype: protein_coding
description:
  Unannotated protein; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.


ensembl_gene_id: GCA_002104455_02146
symbol: ftsH
gene_biotype: protein_coding
description:
  Unannotated protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family.  In the central section; belongs to the AAA ATPase family.


ensembl_gene_id: GCA_002104455_02147
symbol: GCA_002104455_02147
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.


ensembl_gene_id: GCA_002104455_02148
symbol: glmM
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.


ensembl_gene_id: GCA_002104455_02149
symbol: tpiA
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.


ensembl_gene_id: GCA_002104455_02150
symbol: GCA_002104455_02150
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.


ensembl_gene_id: GCA_002104455_02161
symbol: nhaB
gene_biotype: protein_coding
description:
  Unannotated protein; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.


ensembl_gene_id: GCA_002104455_02162
symbol: dsbB
gene_biotype: protein_coding
description:
  Unannotated protein; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family.


ensembl_gene_id: GCA_002104455_02165
symbol: nagZ
gene_biotype: protein_coding
description:
  Unannotated protein; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.


ensembl_gene_id: GCA_002104455_02185
symbol: polA
gene_biotype: protein_coding
description:
  Unannotated protein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.


ensembl_gene_id: GCA_002104455_02192
symbol: GCA_002104455_02192
gene_biotype: protein_coding
description:
  Unannotated protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.


ensembl_gene_id: GCA_002104455_02203
symbol: GCA_002104455_02203
gene_biotype: protein_coding
description:
  Unannotated protein; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate.


ensembl_gene_id: GCA_002104455_02211
symbol: rhlE
gene_biotype: protein_coding
description:
  Unannotated protein; DEAD-box RNA helicase involved in ribosome assembly. Has RNA- dependent ATPase activity and unwinds double-stranded RNA.


ensembl_gene_id: GCA_002104455_02280
symbol: hflX
gene_biotype: protein_coding
description:
  Unannotated protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.


ensembl_gene_id: GCA_002104455_02281
symbol: hfq
gene_biotype: protein_coding
description:
  Unannotated protein; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.


ensembl_gene_id: GCA_002104455_02282
symbol: miaA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.


ensembl_gene_id: GCA_002104455_02283
symbol: mutL
gene_biotype: protein_coding
description:
  Unannotated protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.


ensembl_gene_id: GCA_002104455_02286
symbol: nnrD
gene_biotype: protein_coding
description:
  Unannotated protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.  Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...]


ensembl_gene_id: GCA_002104455_02287
symbol: queG
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family.


ensembl_gene_id: GCA_002104455_02292
symbol: orn
gene_biotype: protein_coding
description:
  Unannotated protein; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family.


ensembl_gene_id: GCA_002104455_02293
symbol: rsgA
gene_biotype: protein_coding
description:
  Unannotated protein; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.


ensembl_gene_id: GCA_002104455_02294
symbol: psd
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).


ensembl_gene_id: GCA_002104455_02302
symbol: GCA_002104455_02302
gene_biotype: protein_coding
description:
  Unannotated protein; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.


ensembl_gene_id: GCA_002104455_02303
symbol: trmL
gene_biotype: protein_coding
description:
  Unannotated protein; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.


ensembl_gene_id: GCA_002104455_02305
symbol: secB
gene_biotype: protein_coding
description:
  Unannotated protein; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.


ensembl_gene_id: GCA_002104455_02306
symbol: GCA_002104455_02306
gene_biotype: protein_coding
description:
  Unannotated protein; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.


ensembl_gene_id: GCA_002104455_02359
symbol: rpoA
gene_biotype: protein_coding
description:
  Unannotated protein; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: GCA_002104455_02360
symbol: rpsD
gene_biotype: protein_coding
description:
  Unannotated protein; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.


ensembl_gene_id: GCA_002104455_02361
symbol: rpsK
gene_biotype: protein_coding
description:
  Unannotated protein; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.


ensembl_gene_id: GCA_002104455_02362
symbol: rpsM
gene_biotype: protein_coding
description:
  Unannotated protein; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family.


ensembl_gene_id: GCA_002104455_02363
symbol: secY
gene_biotype: protein_coding
description:
  Unannotated protein; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.


ensembl_gene_id: GCA_002104455_02366
symbol: rpsE
gene_biotype: protein_coding
description:
  Unannotated protein; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.


ensembl_gene_id: GCA_002104455_02367
symbol: rplR
gene_biotype: protein_coding
description:
  Unannotated protein; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.


ensembl_gene_id: GCA_002104455_02368
symbol: rplF
gene_biotype: protein_coding
description:
  Unannotated protein; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.


ensembl_gene_id: GCA_002104455_02369
symbol: rpsH
gene_biotype: protein_coding
description:
  Unannotated protein; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.


ensembl_gene_id: GCA_002104455_02370
symbol: rpsN
gene_biotype: protein_coding
description:
  Unannotated protein; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family.


ensembl_gene_id: GCA_002104455_02371
symbol: rplE
gene_biotype: protein_coding
description:
  Unannotated protein; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.


ensembl_gene_id: GCA_002104455_02372
symbol: rplX
gene_biotype: protein_coding
description:
  Unannotated protein; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.


ensembl_gene_id: GCA_002104455_02373
symbol: rplN
gene_biotype: protein_coding
description:
  Unannotated protein; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.


ensembl_gene_id: GCA_002104455_02374
symbol: rpsQ
gene_biotype: protein_coding
description:
  Unannotated protein; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.


ensembl_gene_id: GCA_002104455_02376
symbol: rplP
gene_biotype: protein_coding
description:
  Unannotated protein; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.


ensembl_gene_id: GCA_002104455_02377
symbol: rpsC
gene_biotype: protein_coding
description:
  Unannotated protein; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.


ensembl_gene_id: GCA_002104455_02378
symbol: rplV
gene_biotype: protein_coding
description:
  Unannotated protein; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.


ensembl_gene_id: GCA_002104455_02379
symbol: rpsS
gene_biotype: protein_coding
description:
  Unannotated protein; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.


ensembl_gene_id: GCA_002104455_02380
symbol: rplB
gene_biotype: protein_coding
description:
  Unannotated protein; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.


ensembl_gene_id: GCA_002104455_02381
symbol: rplW
gene_biotype: protein_coding
description:
  Unannotated protein; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.


ensembl_gene_id: GCA_002104455_02383
symbol: rplC
gene_biotype: protein_coding
description:
  Unannotated protein; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.


ensembl_gene_id: GCA_002104455_02384
symbol: rpsJ
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.


ensembl_gene_id: GCA_002104455_02385
symbol: fusA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.


ensembl_gene_id: GCA_002104455_02387
symbol: tuf
gene_biotype: protein_coding
description:
  Unannotated protein; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.


ensembl_gene_id: GCA_002104455_02389
symbol: rpsG
gene_biotype: protein_coding
description:
  Unannotated protein; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.


ensembl_gene_id: GCA_002104455_02390
symbol: rpsL
gene_biotype: protein_coding
description:
  Unannotated protein; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.


ensembl_gene_id: GCA_002104455_02393
symbol: rplL
gene_biotype: protein_coding
description:
  Unannotated protein; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family.


ensembl_gene_id: GCA_002104455_02394
symbol: rplJ
gene_biotype: protein_coding
description:
  Unannotated protein; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.


ensembl_gene_id: GCA_002104455_02395
symbol: rplA
gene_biotype: protein_coding
description:
  Unannotated protein; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.


ensembl_gene_id: GCA_002104455_02396
symbol: rplK
gene_biotype: protein_coding
description:
  Unannotated protein; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.


ensembl_gene_id: GCA_002104455_02398
symbol: secE
gene_biotype: protein_coding
description:
  Unannotated protein; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61-gamma family.


ensembl_gene_id: GCA_002104455_02406
symbol: coaX
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.


ensembl_gene_id: GCA_002104455_02407
symbol: birA
gene_biotype: protein_coding
description:
  Unannotated protein; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.


ensembl_gene_id: GCA_002104455_02413
symbol: argH
gene_biotype: protein_coding
description:
  Unannotated protein; In the N-terminal section; belongs to the lyase 1 family. Argininosuccinate lyase subfamily.


ensembl_gene_id: GCA_002104455_02416
symbol: argB
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.


ensembl_gene_id: GCA_002104455_02417
symbol: argC
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.


ensembl_gene_id: GCA_002104455_02423
symbol: aroB
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).


ensembl_gene_id: GCA_002104455_02424
symbol: aroK
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.


ensembl_gene_id: GCA_002104455_02432
symbol: pckA
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.


ensembl_gene_id: GCA_002104455_02493
symbol: rph
gene_biotype: protein_coding
description:
  Unannotated protein; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.


ensembl_gene_id: GCA_002104455_02494
symbol: pyrE
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).


ensembl_gene_id: GCA_002104455_02497
symbol: bioH
gene_biotype: protein_coding
description:
  Unannotated protein; The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.


ensembl_gene_id: GCA_002104455_02500
symbol: nfuA
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.


ensembl_gene_id: GCA_002104455_02504
symbol: cyoE
gene_biotype: protein_coding
description:
  Unannotated protein; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.


ensembl_gene_id: GCA_002104455_02511
symbol: GCA_002104455_02511
gene_biotype: protein_coding
description:
  Unannotated protein; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.


ensembl_gene_id: GCA_002104455_02512
symbol: GCA_002104455_02512
gene_biotype: protein_coding
description:
  Unannotated protein; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).


ensembl_gene_id: GCA_002104455_02513
symbol: lexA
gene_biotype: protein_coding
description:
  Unannotated protein; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.


ensembl_gene_id: GCA_002104455_02602
symbol: recC
gene_biotype: protein_coding
description:
  Unannotated protein; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme  [...]


ensembl_gene_id: GCA_002104455_02628
symbol: moaC
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.


ensembl_gene_id: GCA_002104455_02634
symbol: rlmL
gene_biotype: protein_coding
description:
  Unannotated protein; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family.


ensembl_gene_id: GCA_002104455_02639
symbol: adk
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.


ensembl_gene_id: GCA_002104455_02644
symbol: hisF
gene_biotype: protein_coding
description:
  Unannotated protein; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.


ensembl_gene_id: GCA_002104455_02684
symbol: GCA_002104455_02684
gene_biotype: protein_coding
description:
  Unannotated protein; Recycling of diacylglycerol produced during the turnover of membrane phospholipid.


ensembl_gene_id: GCA_002104455_02695
symbol: hisH
gene_biotype: protein_coding
description:
  Unannotated protein; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.


ensembl_gene_id: GCA_002104455_02697
symbol: hisC
gene_biotype: protein_coding
description:
  Unannotated protein; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.


ensembl_gene_id: GCA_002104455_02698
symbol: hisD
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.


ensembl_gene_id: GCA_002104455_02699
symbol: hisG
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily.


ensembl_gene_id: GCA_002104455_02710
symbol: tpm
gene_biotype: protein_coding
description:
  Unannotated protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.


ensembl_gene_id: GCA_002104455_02715
symbol: rlmM
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.


ensembl_gene_id: GCA_002104455_02719
symbol: xni
gene_biotype: protein_coding
description:
  Unannotated protein; Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.


ensembl_gene_id: GCA_002104455_02722
symbol: queF
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).


ensembl_gene_id: GCA_002104455_02723
symbol: syd
gene_biotype: protein_coding
description:
  Unannotated protein; Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function. Belongs to the Syd family.


ensembl_gene_id: GCA_002104455_02739
symbol: glnD
gene_biotype: protein_coding
description:
  Unannotated protein; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.


ensembl_gene_id: GCA_002104455_02740
symbol: map
gene_biotype: protein_coding
description:
  Unannotated protein; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.


ensembl_gene_id: GCA_002104455_02743
symbol: tsf
gene_biotype: protein_coding
description:
  Unannotated protein; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.


ensembl_gene_id: GCA_002104455_02745
symbol: frr
gene_biotype: protein_coding
description:
  Unannotated protein; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.


ensembl_gene_id: GCA_002104455_02746
symbol: uppS
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.


ensembl_gene_id: GCA_002104455_02748
symbol: dxr
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family.


ensembl_gene_id: GCA_002104455_02752
symbol: lpxD
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily.


ensembl_gene_id: GCA_002104455_02753
symbol: fabZ
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.


ensembl_gene_id: GCA_002104455_02754
symbol: lpxA
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: GCA_002104455_02755
symbol: lpxB
gene_biotype: protein_coding
description:
  Unannotated protein; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: GCA_002104455_02758
symbol: accA
gene_biotype: protein_coding
description:
  Unannotated protein; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.


ensembl_gene_id: GCA_002104455_02759
symbol: tilS
gene_biotype: protein_coding
description:
  Unannotated protein; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.


ensembl_gene_id: GCA_002104455_02760
symbol: sstT
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system). Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: GCA_002104455_02805
symbol: anmK
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family.


ensembl_gene_id: GCA_002104455_02807
symbol: tyrS
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.


ensembl_gene_id: GCA_002104455_02810
symbol: nosZ
gene_biotype: protein_coding
description:
  Unannotated protein; Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide; In the C-terminal section; belongs to the cytochrome c oxidase subunit 2 family.


ensembl_gene_id: GCA_002104455_02821
symbol: mtnN
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.


ensembl_gene_id: GCA_002104455_02836
symbol: rsmC
gene_biotype: protein_coding
description:
  Unannotated protein; Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle; Belongs to the methyltransferase superfamily. RsmC family.


ensembl_gene_id: GCA_002104455_02837
symbol: GCA_002104455_02837
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). Belongs to the DapA family.


ensembl_gene_id: GCA_002104455_02851
symbol: GCA_002104455_02851
gene_biotype: protein_coding
description:
  Unannotated protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.


ensembl_gene_id: GCA_002104455_02853
symbol: lptA
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.


ensembl_gene_id: GCA_002104455_02854
symbol: lptC
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family.


ensembl_gene_id: GCA_002104455_02855
symbol: GCA_002104455_02855
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family.


ensembl_gene_id: GCA_002104455_02864
symbol: murA
gene_biotype: protein_coding
description:
  Unannotated protein; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.


ensembl_gene_id: GCA_002104455_02870
symbol: rplM
gene_biotype: protein_coding
description:
  Unannotated protein; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.


ensembl_gene_id: GCA_002104455_02872
symbol: GCA_002104455_02872
gene_biotype: protein_coding
description:
  Unannotated protein; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.


ensembl_gene_id: GCA_002104455_02888
symbol: rnr
gene_biotype: protein_coding
description:
  Unannotated protein; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.


ensembl_gene_id: GCA_002104455_02893
symbol: rpsR
gene_biotype: protein_coding
description:
  Unannotated protein; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.


ensembl_gene_id: GCA_002104455_02918
symbol: GCA_002104455_02918
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins. Belongs to the MreD family.


ensembl_gene_id: GCA_002104455_02919
symbol: GCA_002104455_02919
gene_biotype: protein_coding
description:
  Unannotated protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.


ensembl_gene_id: GCA_002104455_02955
symbol: rsmH
gene_biotype: protein_coding
description:
  Unannotated protein; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.


ensembl_gene_id: GCA_002104455_02957
symbol: ftsI
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily.


ensembl_gene_id: GCA_002104455_02958
symbol: murE
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.


ensembl_gene_id: GCA_002104455_02959
symbol: murF
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.


ensembl_gene_id: GCA_002104455_02960
symbol: mraY
gene_biotype: protein_coding
description:
  Unannotated protein; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.


ensembl_gene_id: GCA_002104455_02961
symbol: murD
gene_biotype: protein_coding
description:
  Unannotated protein; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.


ensembl_gene_id: GCA_002104455_02962
symbol: ftsW
gene_biotype: protein_coding
description:
  Unannotated protein; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily.


ensembl_gene_id: GCA_002104455_02963
symbol: murG
gene_biotype: protein_coding
description:
  Unannotated protein; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.


ensembl_gene_id: GCA_002104455_02966
symbol: ftsQ
gene_biotype: protein_coding
description:
  Unannotated protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.


ensembl_gene_id: GCA_002104455_02967
symbol: ftsA
gene_biotype: protein_coding
description:
  Unannotated protein; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.


ensembl_gene_id: GCA_002104455_02968
symbol: ftsZ
gene_biotype: protein_coding
description:
  Unannotated protein; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.


ensembl_gene_id: GCA_002104455_02969
symbol: lpxC
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family.


ensembl_gene_id: GCA_002104455_02972
symbol: secA
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family.


ensembl_gene_id: GCA_002104455_02974
symbol: yacG
gene_biotype: protein_coding
description:
  Unannotated protein; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C- terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.


ensembl_gene_id: GCA_002104455_02975
symbol: zapD
gene_biotype: protein_coding
description:
  Unannotated protein; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.


ensembl_gene_id: GCA_002104455_02976
symbol: coaE
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.


ensembl_gene_id: GCA_002104455_02977
symbol: GCA_002104455_02977
gene_biotype: protein_coding
description:
  Unannotated protein; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.


ensembl_gene_id: GCA_002104455_02987
symbol: GCA_002104455_02987
gene_biotype: protein_coding
description:
  Unannotated protein; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


ensembl_gene_id: GCA_002104455_02988
symbol: GCA_002104455_02988
gene_biotype: protein_coding
description:
  Unannotated protein; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


ensembl_gene_id: GCA_002104455_03018
symbol: queE
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.


ensembl_gene_id: GCA_002104455_03019
symbol: queC
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.


ensembl_gene_id: GCA_002104455_03025
symbol: gloB
gene_biotype: protein_coding
description:
  Unannotated protein; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.


ensembl_gene_id: GCA_002104455_03030
symbol: pyrD
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.


ensembl_gene_id: GCA_002104455_03040
symbol: proQ
gene_biotype: protein_coding
description:
  Unannotated protein; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities; Belongs to the ProQ family.


ensembl_gene_id: GCA_002104455_03046
symbol: prpB
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.


ensembl_gene_id: GCA_002104455_03052
symbol: tmk
gene_biotype: protein_coding
description:
  Unannotated protein; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.


ensembl_gene_id: GCA_002104455_03053
symbol: mltG
gene_biotype: protein_coding
description:
  Unannotated protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family.


ensembl_gene_id: GCA_002104455_03055
symbol: GCA_002104455_03055
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.


ensembl_gene_id: GCA_002104455_03057
symbol: GCA_002104455_03057
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: GCA_002104455_03059
symbol: plsX
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.


ensembl_gene_id: GCA_002104455_03062
symbol: GCA_002104455_03062
gene_biotype: protein_coding
description:
  Unannotated protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes 7- methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids; Belongs to the Maf family. YceF subfamily.


ensembl_gene_id: GCA_002104455_03064
symbol: rne
gene_biotype: protein_coding
description:
  Unannotated protein; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily.


ensembl_gene_id: GCA_002104455_03065
symbol: GCA_002104455_03065
gene_biotype: protein_coding
description:
  Unannotated protein; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.


ensembl_gene_id: GCA_002104455_03081
symbol: uvrC
gene_biotype: protein_coding
description:
  Unannotated protein; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.


ensembl_gene_id: GCA_002104455_03084
symbol: fabA
gene_biotype: protein_coding
description:
  Unannotated protein; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.


ensembl_gene_id: GCA_002104455_03085
symbol: gltX
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.


ensembl_gene_id: GCA_002104455_03090
symbol: GCA_002104455_03090
gene_biotype: protein_coding
description:
  Unannotated protein; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.


ensembl_gene_id: GCA_002104455_03091
symbol: mtnA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).


ensembl_gene_id: GCA_002104455_03098
symbol: mtaD
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.


ensembl_gene_id: GCA_002104455_03104
symbol: proS
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacyl [...]


ensembl_gene_id: GCA_002104455_03126
symbol: GCA_002104455_03126
gene_biotype: protein_coding
description:
  Unannotated protein; Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.


ensembl_gene_id: GCA_002104455_03134
symbol: purN
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.


ensembl_gene_id: GCA_002104455_03155
symbol: dnaQ
gene_biotype: protein_coding
description:
  Unannotated protein; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.


ensembl_gene_id: GCA_002104455_03183
symbol: GCA_002104455_03183
gene_biotype: protein_coding
description:
  Unannotated protein; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.


ensembl_gene_id: GCA_002104455_03185
symbol: ubiG
gene_biotype: protein_coding
description:
  Unannotated protein; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family.


ensembl_gene_id: GCA_002104455_03187
symbol: serC
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.


ensembl_gene_id: GCA_002104455_03188
symbol: aroA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.


ensembl_gene_id: GCA_002104455_03190
symbol: GCA_002104455_03190
gene_biotype: protein_coding
description:
  Unannotated protein; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.


ensembl_gene_id: GCA_002104455_03193
symbol: lapB
gene_biotype: protein_coding
description:
  Unannotated protein; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane; Belongs to the LapB family.


ensembl_gene_id: GCA_002104455_03194
symbol: pyrF
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.


ensembl_gene_id: GCA_002104455_03197
symbol: add
gene_biotype: protein_coding
description:
  Unannotated protein; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.


ensembl_gene_id: GCA_002104455_03201
symbol: dnaE2
gene_biotype: protein_coding
description:
  Unannotated protein; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.


ensembl_gene_id: GCA_002104455_03216
symbol: edd
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family.


ensembl_gene_id: GCA_002104455_03220
symbol: GCA_002104455_03220
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.


ensembl_gene_id: GCA_002104455_03246
symbol: azoR
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity; Belongs to the azoreductase type 1 family.


ensembl_gene_id: GCA_002104455_03258
symbol: minC
gene_biotype: protein_coding
description:
  Unannotated protein; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family.


ensembl_gene_id: GCA_002104455_03260
symbol: minE
gene_biotype: protein_coding
description:
  Unannotated protein; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.


ensembl_gene_id: GCA_002104455_03309
symbol: bioD
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.


ensembl_gene_id: GCA_002104455_03310
symbol: bioC
gene_biotype: protein_coding
description:
  Unannotated protein; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.


ensembl_gene_id: GCA_002104455_03312
symbol: bioB
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.


ensembl_gene_id: GCA_002104455_03313
symbol: bioA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.


ensembl_gene_id: GCA_002104455_03326
symbol: serS
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).


ensembl_gene_id: GCA_002104455_03327
symbol: crcB
gene_biotype: protein_coding
description:
  Unannotated protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.


ensembl_gene_id: GCA_002104455_03329
symbol: lolA
gene_biotype: protein_coding
description:
  Unannotated protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).


ensembl_gene_id: GCA_002104455_03338
symbol: obg
gene_biotype: protein_coding
description:
  Unannotated protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.


ensembl_gene_id: GCA_002104455_03340
symbol: rplU
gene_biotype: protein_coding
description:
  Unannotated protein; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.


ensembl_gene_id: GCA_002104455_03350
symbol: cobQ
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.


ensembl_gene_id: GCA_002104455_03351
symbol: GCA_002104455_03351
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.


ensembl_gene_id: GCA_002104455_03352
symbol: cobS
gene_biotype: protein_coding
description:
  Unannotated protein; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.


ensembl_gene_id: GCA_002104455_03353
symbol: cobT
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).


ensembl_gene_id: GCA_002104455_03371
symbol: GCA_002104455_03371
gene_biotype: protein_coding
description:
  Unannotated protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: GCA_002104455_03374
symbol: rsmI
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.


ensembl_gene_id: GCA_002104455_03377
symbol: gmhA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.


ensembl_gene_id: GCA_002104455_03380
symbol: GCA_002104455_03380
gene_biotype: protein_coding
description:
  Unannotated protein; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).


ensembl_gene_id: GCA_002104455_03386
symbol: GCA_002104455_03386
gene_biotype: protein_coding
description:
  Unannotated protein; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family.


ensembl_gene_id: GCA_002104455_03390
symbol: dksA
gene_biotype: protein_coding
description:
  Unannotated protein; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.


ensembl_gene_id: GCA_002104455_03391
symbol: gluQ
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.


ensembl_gene_id: GCA_002104455_03392
symbol: pcnB
gene_biotype: protein_coding
description:
  Unannotated protein; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control. Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.


ensembl_gene_id: GCA_002104455_03394
symbol: panB
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.


ensembl_gene_id: GCA_002104455_03395
symbol: panC
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.


ensembl_gene_id: GCA_002104455_03402
symbol: efp
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation; Belongs to the elongation factor P family.


ensembl_gene_id: GCA_002104455_03427
symbol: groL
gene_biotype: protein_coding
description:
  Unannotated protein; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.


ensembl_gene_id: GCA_002104455_03428
symbol: groS
gene_biotype: protein_coding
description:
  Unannotated protein; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.


ensembl_gene_id: GCA_002104455_03430
symbol: dsbD
gene_biotype: protein_coding
description:
  Unannotated protein; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily.


ensembl_gene_id: GCA_002104455_03434
symbol: aroQ
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.


ensembl_gene_id: GCA_002104455_03435
symbol: GCA_002104455_03435
gene_biotype: protein_coding
description:
  Unannotated protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.


ensembl_gene_id: GCA_002104455_03438
symbol: GCA_002104455_03438
gene_biotype: protein_coding
description:
  Unannotated protein; Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate; Belongs to the peptidase C56 family.


ensembl_gene_id: GCA_002104455_03453
symbol: fadB
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: GCA_002104455_03456
symbol: cysH
gene_biotype: protein_coding
description:
  Unannotated protein; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.


ensembl_gene_id: GCA_002104455_03457
symbol: cysI
gene_biotype: protein_coding
description:
  Unannotated protein; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.


ensembl_gene_id: GCA_002104455_03458
symbol: GCA_002104455_03458
gene_biotype: protein_coding
description:
  Unannotated protein; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.


ensembl_gene_id: GCA_002104455_03477
symbol: GCA_002104455_03477
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.


ensembl_gene_id: GCA_002104455_03488
symbol: GCA_002104455_03488
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.


ensembl_gene_id: GCA_002104455_03500
symbol: GCA_002104455_03500
gene_biotype: protein_coding
description:
  Unannotated protein; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.


ensembl_gene_id: GCA_002104455_03518
symbol: GCA_002104455_03518
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in cell division; probably involved in intracellular septation; Belongs to the YciB family.


ensembl_gene_id: GCA_002104455_03540
symbol: ackA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.


ensembl_gene_id: GCA_002104455_03541
symbol: GCA_002104455_03541
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.


ensembl_gene_id: GCA_002104455_03544
symbol: dapE
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily.


ensembl_gene_id: GCA_002104455_03552
symbol: sucD
gene_biotype: protein_coding
description:
  Unannotated protein; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.


ensembl_gene_id: GCA_002104455_03553
symbol: sucC
gene_biotype: protein_coding
description:
  Unannotated protein; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.


ensembl_gene_id: GCA_002104455_03554
symbol: GCA_002104455_03554
gene_biotype: protein_coding
description:
  Unannotated protein; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).


ensembl_gene_id: GCA_002104455_03568
symbol: pnp
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.


ensembl_gene_id: GCA_002104455_03572
symbol: rpsO
gene_biotype: protein_coding
description:
  Unannotated protein; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.


ensembl_gene_id: GCA_002104455_03573
symbol: truB
gene_biotype: protein_coding
description:
  Unannotated protein; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.


ensembl_gene_id: GCA_002104455_03574
symbol: rbfA
gene_biotype: protein_coding
description:
  Unannotated protein; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.


ensembl_gene_id: GCA_002104455_03575
symbol: infB
gene_biotype: protein_coding
description:
  Unannotated protein; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.


ensembl_gene_id: GCA_002104455_03579
symbol: rnfA
gene_biotype: protein_coding
description:
  Unannotated protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.


ensembl_gene_id: GCA_002104455_03580
symbol: rnfB
gene_biotype: protein_coding
description:
  Unannotated protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.


ensembl_gene_id: GCA_002104455_03581
symbol: rnfC
gene_biotype: protein_coding
description:
  Unannotated protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.


ensembl_gene_id: GCA_002104455_03582
symbol: rnfD
gene_biotype: protein_coding
description:
  Unannotated protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the NqrB/RnfD family.


ensembl_gene_id: GCA_002104455_03583
symbol: rnfG
gene_biotype: protein_coding
description:
  Unannotated protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the RnfG family.


ensembl_gene_id: GCA_002104455_03585
symbol: nth
gene_biotype: protein_coding
description:
  Unannotated protein; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.


