# pathwayInfo

id: SM00609
description: Vault protein Inter-alpha-Trypsin domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00609
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00609_Vault_protein_Inter-alpha-Trypsin_domain


id: SM00613
description: Domain present in PNGases and other hypothetical proteins
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00613
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00613_Domain_present_in_PNGases_and_other_hypothetical_proteins


id: SM00648
description: Suppressor-of-White-APricot splicing regulator
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00648
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00648_Suppressor-of-White-APricot_splicing_regulator


id: SM00652
description: Eukaryotic translation initiation factor 1A
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00652
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00652_Eukaryotic_translation_initiation_factor_1A


id: SM00653
description: Domain present in translation initiation factor eIF2B and eIF5
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00653
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00653_Domain_present_in_translation_initiation_factor_eIF2B_and_eIF5


id: SM00664
description: Possible catecholamine-binding domain present in a variety of eukaryotic proteins.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00664
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00664_Possible_catecholamine-binding_domain_present_in_a_variety_of_eukaryotic_proteins.


id: SM00665
description: Cytochrome b-561 / ferric reductase transmembrane domain.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00665
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00665_Cytochrome_b-561_/_ferric_reductase_transmembrane_domain.


id: SM00667
description: Lissencephaly type-1-like homology motif
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00667
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00667_Lissencephaly_type-1-like_homology_motif


id: SM00670
description: Large family of predicted nucleotide-binding domains
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00670
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00670_Large_family_of_predicted_nucleotide-binding_domains


id: SM00672
description: Putative lipopolysaccharide-modifying enzyme.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00672
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00672_Putative_lipopolysaccharide-modifying_enzyme.


id: SM00673
description: Domain in CAPs (cyclase-associated proteins) and X-linked retinitis pigmentosa 2 gene product.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00673
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00673_Domain_in_CAPs_(cyclase-associated_proteins)_and_X-linked_retinitis_pigmentosa_2_gene_product.


id: SM00674
description: Putative DNA-binding domain in centromere protein B, mouse jerky and transposases.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00674
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00674_Putative_DNA-binding_domain_in_centromere_protein_B,_mouse_jerky_and_transposases.


id: SM00676
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00676
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00676_Domains_in_hypothetical_proteins_in_Drosophila,_C._elegans_and_mammals._Occurs_singly_in_some_nucleoside_diphosphate_kinases.

description:
  Domains in hypothetical proteins in Drosophila, C. elegans and mammals. Occurs singly in some nucleoside diphosphate kinases.


id: SM00678
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00678
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00678_Domain_in_Deltex_and_TRIP12_homologues._Possibly_involved_in_regulation_of_ubiquitin-mediated_proteolysis.

description:
  Domain in Deltex and TRIP12 homologues. Possibly involved in regulation of ubiquitin-mediated proteolysis.


id: SM00679
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00679
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00679_Repeated_motif_present_between_transmembrane_helices_in_cystinosin,_yeast_ERS1p,_mannose-P-dolichol_utilization_defect_1,_and_other_hypothetical_proteins.

description:
  Repeated motif present between transmembrane helices in cystinosin, yeast ERS1p, mannose-P-dolichol utilization defect 1, and other hypothetical proteins.


id: SM00684
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00684
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00684_Tandem_repeat_in_fly_CG14066_(La_related_protein),_human_KIAA0731_and_worm_R144.7._Unknown_function.

description:
  Tandem repeat in fly CG14066 (La related protein), human KIAA0731 and worm R144.7. Unknown function.


id: SM00685
description: Repeats in fly CG4713, worm Y37H9A.3 and human FLJ20241.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00685
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00685_Repeats_in_fly_CG4713,_worm_Y37H9A.3_and_human_FLJ20241.


id: SM00692
description: Zinc finger domain in CG10631, C. elegans LIN-15B and human P52rIPK.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00692
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00692_Zinc_finger_domain_in_CG10631,_C._elegans_LIN-15B_and_human_P52rIPK.


id: SM00698
description: Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00698
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00698_Possible_plasma_membrane-binding_motif_in_junctophilins,_PIP-5-kinases_and_protein_kinases.


id: SM00702
description: Prolyl 4-hydroxylase alpha subunit homologues.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00702
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00702_Prolyl_4-hydroxylase_alpha_subunit_homologues.


id: SM00703
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00703
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00703_N-terminal_domain_in_C._elegans_NRF-6_(Nose_Resistant_to_Fluoxetine-4)_and_NDG-4_(resistant_to_nordihydroguaiaretic_acid-4).

description:
  N-terminal domain in C. elegans NRF-6 (Nose Resistant to Fluoxetine-4) and NDG-4 (resistant to nordihydroguaiaretic acid-4).


id: SM00704
description: CDGSH-type zinc finger. Function unknown.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00704
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00704_CDGSH-type_zinc_finger._Function_unknown.


id: SM00706
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00706
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00706_Beta_propeller_repeats_in_Physarum_polycephalum_tectonins,_Limulus_lectin_L-6_and_animal_hypothetical_proteins.

description:
  Beta propeller repeats in Physarum polycephalum tectonins, Limulus lectin L-6 and animal hypothetical proteins.


id: SM00707
description: Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00707
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00707_Repeat_in_Drosophila_CG10860,_human_KIAA0680_and_C._elegans_F26H9.2


id: SM00709
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00709
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00709_Duplicated_domain_in_the_epidermal_growth_factor-_and_elongation_factor-1alpha-binding_protein_Zpr1._Also_present_in_archaeal_proteins.

description:
  Duplicated domain in the epidermal growth factor- and elongation factor-1alpha-binding protein Zpr1. Also present in archaeal proteins.


id: SM00711
description: Short repeats in human TONDU, fly vestigial and other proteins.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00711
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00711_Short_repeats_in_human_TONDU,_fly_vestigial_and_other_proteins.


id: SM00712
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00712
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00712_DNA/RNA-binding_repeats_in_PUR-alpha/beta/gamma_and_in_hypothetical_proteins_from_spirochetes_and_the_Bacteroides-Cytophaga-Flexibacter_bacteria.

description:
  DNA/RNA-binding repeats in PUR-alpha/beta/gamma and in hypothetical proteins from spirochetes and the Bacteroides-Cytophaga-Flexibacter bacteria.


id: SM00714
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00714
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00714_Possible_membrane-associated_motif_in_LPS-induced_tumor_necrosis_factor_alpha_factor_(LITAF),_also_known_as_PIG7,_and_other_animal_proteins.

description:
  Possible membrane-associated motif in LPS-induced tumor necrosis factor alpha factor (LITAF), also known as PIG7, and other animal proteins.


id: SM00715
description: Domain in the RNA-binding Lupus La protein
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00715
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00715_Domain_in_the_RNA-binding_Lupus_La_protein


id: SM00717
description: SANT SWI3, ADA2, N-CoR and TFIIIB DNA-binding domains
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00717
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00717_SANT__SWI3,_ADA2,_N-CoR_and_TFIIIB_DNA-binding_domains


id: SM00719
description: Short conserved domain in transcriptional regulators.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00719
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00719_Short_conserved_domain_in_transcriptional_regulators.


id: SM00722
description: Domain present in carbohydrate binding proteins and sugar hydrolses
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00722
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00722_Domain_present_in_carbohydrate_binding_proteins_and_sugar_hydrolses


id: SM00723
description: Adhesion-associated domain present in MUC4 and other proteins
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00723
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00723_Adhesion-associated_domain_present_in_MUC4_and_other_proteins


id: SM00729
description: Elongator protein 3, MiaB family, Radical SAM
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00729
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00729_Elongator_protein_3,_MiaB_family,_Radical_SAM


id: SM00730
description: Presenilin, signal peptide peptidase, family
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00730
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00730_Presenilin,_signal_peptide_peptidase,_family


id: SM00733
description: Mitochondrial termination factor repeats
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00733
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00733_Mitochondrial_termination_factor_repeats


id: SM00736
description: Dystroglycan-type cadherin-like domains.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00736
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00736_Dystroglycan-type_cadherin-like_domains.


id: SM00737
description: Domain involved in innate immunity and lipid metabolism.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00737
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00737_Domain_involved_in_innate_immunity_and_lipid_metabolism.


id: SM00738
description: In Spt5p, this domain may confer affinity for Spt4p. It possesses a RNP-like fold.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00738
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00738_In_Spt5p,_this_domain_may_confer_affinity_for_Spt4p._It_possesses_a_RNP-like_fold.


id: SM00742
description: Rho effector or protein kinase C-related kinase homology region 1 homologues
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00742
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00742_Rho_effector_or_protein_kinase_C-related_kinase_homology_region_1_homologues


id: SM00744
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00744
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00744_The_RING-variant_domain_is_a_C4HC3_zinc-finger_like_motif_found_in_a_number_of_cellular_and_viral_proteins._Some_of_these_proteins_have_been_shown_both_in_vivo_and_in_vitro_to_have_ubiquitin_E3_ligase_activity.

description:
  The RING-variant domain is a C4HC3 zinc-finger like motif found in a number of cellular and viral proteins. Some of these proteins have been shown both in vivo and in vitro to have ubiquitin E3 ligase activity.


id: SM00745
description: Microtubule Interacting and Trafficking molecule domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00745
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00745_Microtubule_Interacting_and_Trafficking_molecule_domain


id: SM00748
description: Higher Eukarytoes and Prokaryotes Nucleotide-binding domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00748
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00748_Higher_Eukarytoes_and_Prokaryotes_Nucleotide-binding_domain


id: SM00751
description: Domain in transcription factors and synapse-associated proteins
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00751
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00751_Domain_in_transcription_factors_and_synapse-associated_proteins


id: SM00752
description: Horizontally Transferred TransMembrane Domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00752
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00752_Horizontally_Transferred_TransMembrane_Domain


id: SM00754
description: A domain in the BMP inhibitor chordin and in microbial proteins.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00754
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00754_A_domain_in_the_BMP_inhibitor_chordin_and_in_microbial_proteins.


id: SM00755
description: golgin-97, RanBP2alpha,Imh1p and p230/golgin-245
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00755
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00755_golgin-97,_RanBP2alpha,Imh1p_and_p230/golgin-245


id: SM00756
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00756
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00756_Family_of_likely_enzymes_that_includes_the_catalytic_subunit_of_vitamin_K_epoxide_reductase._Bacterial_homologues_are_fused_to_members_of_the_thioredoxin_family_of_oxidoreductases.

description:
  Family of likely enzymes that includes the catalytic subunit of vitamin K epoxide reductase. Bacterial homologues are fused to members of the thioredoxin family of oxidoreductases.


id: SM00758
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00758
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00758_Domain_in_bacterial_beta-glucosidases_other_glycosidases,_glycosyltransferases,_proteases,_amidases,_yeast_adhesins,_and_bacterial_toxins.

description:
  Domain in bacterial beta-glucosidases other glycosidases, glycosyltransferases, proteases, amidases, yeast adhesins, and bacterial toxins.


id: SM00765
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00765
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00765_The_MANEC_domain_was_formerly_called_MANSC._This_domain,_comprising_8_conserved_cysteines,_is_found_in_the_N_terminus_of_higher_multicellular_animal_membrane_and_extracellular_proteins._It_is_postulated_that_this_domain_may_play_a_role_in_the_...

description:
  The MANEC domain was formerly called MANSC. This domain, comprising 8 conserved cysteines, is found in the N terminus of higher multicellular animal membrane and extracellular proteins. It is postulated that this domain may play a role in the ...


id: SM00775
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00775
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00775_This_domain_is_found_in_Saccharomyces_cerevisiae_protein_SMP2,_proteins_with_an_N-terminal_lipin_domain_and_phosphatidylinositol_transfer_proteins._SMP2_is_involved_in_plasmid_maintenance_and_respiration._Lipin_proteins_are_involved_in_adipose_tissue_...

description:
  This domain is found in Saccharomyces cerevisiae protein SMP2, proteins with an N-terminal lipin domain and phosphatidylinositol transfer proteins. SMP2 is involved in plasmid maintenance and respiration. Lipin proteins are involved in adipose tissue ...


id: SM00799
description: Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00799
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00799_Domain_found_in_a_variety_of_signalling_proteins,_always_encircled_by_uDENN_and_dDENN


id: SM00800
description: Domain always found upstream of DENN domain, found in a variety of signalling proteins
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00800
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00800_Domain_always_found_upstream_of_DENN_domain,_found_in_a_variety_of_signalling_proteins


id: SM00801
description: Domain always found downstream of DENN domain, found in a variety of signalling proteins
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00801
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00801_Domain_always_found_downstream_of_DENN_domain,_found_in_a_variety_of_signalling_proteins


id: SM00803
description: TATA box binding protein associated factor
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00803
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00803_TATA_box_binding_protein_associated_factor


id: SM00804
description: C-terminal domain of vertebrate Tap protein
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00804
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00804_C-terminal_domain_of_vertebrate_Tap_protein


id: SM00805
description: Angiotensin II, type I receptor-associated protein
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00805
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00805_Angiotensin_II,_type_I_receptor-associated_protein


id: SM00818
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00818
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00818_Amelogenins,_cell_adhesion_proteins,_play_a_role_in_the_biomineralisation_of_teeth._They_seem_to_regulate_formation_of_crystallites_during_the_secretory_stage_of_tooth_enamel_development_and_are_thought_to_play_a_major_role_in_the_structural_...

description:
  Amelogenins, cell adhesion proteins, play a role in the biomineralisation of teeth. They seem to regulate formation of crystallites during the secretory stage of tooth enamel development and are thought to play a major role in the structural ...


id: SM00822
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00822
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00822_This_enzymatic_domain_is_part_of_bacterial_polyketide_synthases_and_catalyses_the_first_step_in_the_reductive_modification_of_the_beta-carbonyl_centres_in_the_growing_polyketide_chain._It_uses_NADPH_to_reduce_the_keto_group_to_a_hydroxy_group.

description:
  This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group.


id: SM00827
description: Acyl transferase domain in polyketide synthase (PKS) enzymes.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00827
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00827_Acyl_transferase_domain_in_polyketide_synthase_(PKS)_enzymes.


id: SM00832
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00832
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00832_This_domain_contains_8_conserved_cysteine_residues,_but_this_family_only_contains_7_of_them_to_overlaps_with_other_domains._It_is_found_in_disease-related_proteins_including_von_Willebrand_factor,_Alpha_tectorin,_Zonadhesin_and_Mucin.

description:
  This domain contains 8 conserved cysteine residues, but this family only contains 7 of them to overlaps with other domains. It is found in disease-related proteins including von Willebrand factor, Alpha tectorin, Zonadhesin and Mucin.


id: SM00833
description: Cobalamin synthesis protein cobW C-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00833
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00833_Cobalamin_synthesis_protein_cobW_C-terminal_domain


id: SM00839
description: Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00839
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00839_Glutamate/Leucine/Phenylalanine/Valine_dehydrogenase


id: SM00846
description: Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00846
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00846_Glyceraldehyde_3-phosphate_dehydrogenase,_NAD_binding_domain


id: SM00847
description: Helicase associated domain (HA2) Add an annotation
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00847
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00847_Helicase_associated_domain_(HA2)__Add_an_annotation


id: SM00848
description: Cathepsin propeptide inhibitor domain (I29)
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00848
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00848_Cathepsin_propeptide_inhibitor_domain_(I29)


id: SM00858
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00858
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00858_This_domain_family_includes_a_range_of_different_proteins._Such_as_antifreeze_proteins_and_flagellar_FlgA_proteins,_and_CpaB_pilus_proteins.

description:
  This domain family includes a range of different proteins. Such as antifreeze proteins and flagellar FlgA proteins, and CpaB pilus proteins.


id: SM00861
description: Transketolase, pyrimidine binding domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00861
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00861_Transketolase,_pyrimidine_binding_domain


id: SM00863
description: Threonyl and Alanyl tRNA synthetase second additional domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00863
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00863_Threonyl_and_Alanyl_tRNA_synthetase_second_additional_domain


id: SM00870
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00870
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00870_Asparaginase,_which_is_found_in_various_plant,_animal_and_bacterial_cells,_catalyses_the_deamination_of_asparagine_to_yield_aspartic_acid_and_an_ammonium_ion,_resulting_in_a_depletion_of_free_circulatory_asparagine_in_plasma_PUBMED:3026924._The_...

description:
  Asparaginase, which is found in various plant, animal and bacterial cells, catalyses the deamination of asparagine to yield aspartic acid and an ammonium ion, resulting in a depletion of free circulatory asparagine in plasma PUBMED:3026924. The ...


id: SM00879
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00879
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00879_The_Brix_domain_is_found_in_a_number_of_eukaryotic_proteins_including_SSF_proteins_from_yeast_and_humans,_Arabidopsis_thaliana_Peter_Pan-like_protein_and_several_hypothetical_proteins.

description:
  The Brix domain is found in a number of eukaryotic proteins including SSF proteins from yeast and humans, Arabidopsis thaliana Peter Pan-like protein and several hypothetical proteins.


id: SM00896
description: Ferredoxin-fold anticodon binding domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00896
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00896_Ferredoxin-fold_anticodon_binding_domain


id: SM00898
description: Formamidopyrimidine-DNA glycosylase N-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00898
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00898_Formamidopyrimidine-DNA_glycosylase_N-terminal_domain


id: SM00910
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00910
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00910_The_HIRAN_protein_(HIP116,_Rad5p_N-terminal)_is_found_in_the_N-terminal_regions_of_the_SWI2/SNF2_proteins_typified_by_HIP116_and_Rad5p._HIRAN_is_found_as_a_standalone_protein_in_several_bacteria_and_prophages,_or_fused_to_other_catalytic_domains,_...

description:
  The HIRAN protein (HIP116, Rad5p N-terminal) is found in the N-terminal regions of the SWI2/SNF2 proteins typified by HIP116 and Rad5p. HIRAN is found as a standalone protein in several bacteria and prophages, or fused to other catalytic domains, ...


id: SM00916
description: Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00916
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00916_Mitochondrial_ribosomal_protein_L51_/_S25_/_CI-B8_domain


id: SM00918
description: Ligated ion channel L-glutamate- and glycine-binding site
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00918
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00918_Ligated_ion_channel_L-glutamate-_and_glycine-binding_site


id: SM00920
description: Class II histocompatibility antigen, alpha domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00920
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00920_Class_II_histocompatibility_antigen,_alpha_domain


id: SM00921
description: Class II histocompatibility antigen, beta domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00921
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00921_Class_II_histocompatibility_antigen,_beta_domain


id: SM00922
description: Mandelate racemase / muconate lactonizing enzyme, C-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00922
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00922_Mandelate_racemase_/_muconate_lactonizing_enzyme,_C-terminal_domain


id: SM00928
description: NADH-ubiquinone oxidoreductase-F iron-sulfur binding region
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00928
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00928_NADH-ubiquinone_oxidoreductase-F_iron-sulfur_binding_region


id: SM00929
description: NADH-ubiquinone oxidoreductase-G iron-sulfur binding region
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00929
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00929_NADH-ubiquinone_oxidoreductase-G_iron-sulfur_binding_region


id: SM00934
description: Orotidine 5-phosphate decarboxylase / HUMPS family
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00934
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00934_Orotidine_5-phosphate_decarboxylase_/_HUMPS_family


id: SM00937
description: This domain is found in peptide chain release factors.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00937
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00937_This_domain_is_found_in_peptide_chain_release_factors.


id: SM00941
description: Pyrimidine nucleoside phosphorylase C-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00941
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00941_Pyrimidine_nucleoside_phosphorylase_C-terminal_domain


id: SM00948
description: Proteasome subunit A N-terminal signature Add an annotation
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00948
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00948_Proteasome_subunit_A_N-terminal_signature__Add_an_annotation


id: SM00949
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00949
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00949_This_domain_is_named_PAZ_after_the_proteins_Piwi_Argonaut_and_Zwille._This_domain_is_found_in_two_families_of_proteins_that_are_involved_in_post-transcriptional_gene_silencing._These_are_the_Piwi_family_and_the_Dicer_family,_that_includes_the_Carpel_...

description:
  This domain is named PAZ after the proteins Piwi Argonaut and Zwille. This domain is found in two families of proteins that are involved in post-transcriptional gene silencing. These are the Piwi family and the Dicer family, that includes the Carpel ...


id: SM00950
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00950
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00950_This_domain_is_found_in_the_protein_Piwi_and_its_relatives._The_function_of_this_domain_is_the_dsRNA_guided_hydrolysis_of_ssRNA._Determination_of_the_crystal_structure_of_Argonaute_reveals_that_PIWI_is_an_RNase_H_domain,_and_identifies_Argonaute_as_...

description:
  This domain is found in the protein Piwi and its relatives. The function of this domain is the dsRNA guided hydrolysis of ssRNA. Determination of the crystal structure of Argonaute reveals that PIWI is an RNase H domain, and identifies Argonaute as ...


id: SM00951
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00951
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00951_QLQ_is_named_after_the_conserved_Gln,_Leu,_Gln_motif._QLQ_is_found_at_the_N-terminus_of_SWI2/SNF2_protein,_which_has_been_shown_to_be_involved_in_protein-protein_interactions._QLQ_has_been_postulated_to_be_involved_in_mediating_protein_interactions_...

description:
  QLQ is named after the conserved Gln, Leu, Gln motif. QLQ is found at the N-terminus of SWI2/SNF2 protein, which has been shown to be involved in protein-protein interactions. QLQ has been postulated to be involved in mediating protein interactions ...


id: SM00952
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00952
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00952_This_domain_is_found_in_various_eukaryotic_species,_particularly_in_apicomplexans_such_as_Plasmodium_falciparum,_where_it_is_found_in_proteins_that_are_important_in_various_parasite-host_cell_interactions._It_is_thought_to_be_an_RNA-binding_domain_...

description:
  This domain is found in various eukaryotic species, particularly in apicomplexans such as Plasmodium falciparum, where it is found in proteins that are important in various parasite-host cell interactions. It is thought to be an RNA-binding domain ...


id: SM00955
description: This domain is the catalytic domain of ribonuclease II.PUBMED:16806266
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00955
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00955_This_domain_is_the_catalytic_domain_of_ribonuclease_II.PUBMED:16806266


id: SM00956
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00956
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00956_This_DNA-binding_domain_is_found_in_the_RecQ_helicase_among_others_and_has_a_helix-turn-helix_structure._The_RQC_domain,_found_only_in_RecQ_family_enzymes,_is_a_high_affinity_G4_DNA_binding_domain_PUBMED:16530788.

description:
  This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure. The RQC domain, found only in RecQ family enzymes, is a high affinity G4 DNA binding domain PUBMED:16530788.


id: SM00963
description: SRP54-type protein, helical bundle domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00963
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00963_SRP54-type_protein,_helical_bundle_domain


id: SM00964
description: STAT protein, protein interaction domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00964
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00964_STAT_protein,_protein_interaction_domain


id: SM00967
description: RNA 2-O ribose methyltransferase substrate binding
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00967
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00967_RNA_2-O_ribose_methyltransferase_substrate_binding


id: SM00969
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00969
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00969_The_SOCS_box_acts_as_a_bridge_between_specific_substrate-_binding_domains_and_more_generic_proteins_that_comprise_a_large_family_of_E3_ubiquitin_protein_ligases.

description:
  The SOCS box acts as a bridge between specific substrate- binding domains and more generic proteins that comprise a large family of E3 ubiquitin protein ligases.


id: SM00975
description: Telomerase ribonucleoprotein complex - RNA binding domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00975
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00975_Telomerase_ribonucleoprotein_complex_-_RNA_binding_domain


id: SM00976
description: Telomeric single stranded DNA binding POT1/CDC13
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00976
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00976_Telomeric_single_stranded_DNA_binding_POT1/CDC13


id: SM00978
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00978
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00978_Tim44_is_an_essential_component_of_the_machinery_that_mediates_the_translocation_of_nuclear-encoded_proteins_across_the_mitochondrial_inner_membrane_PUBMED:10430866._Tim44_is_thought_to_bind_phospholipids_of_the_mitochondrial_inner_membrane_both_by_...

description:
  Tim44 is an essential component of the machinery that mediates the translocation of nuclear-encoded proteins across the mitochondrial inner membrane PUBMED:10430866. Tim44 is thought to bind phospholipids of the mitochondrial inner membrane both by ...


id: SM00981
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00981
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00981_The_THUMP_domain_is_named_after_after_thiouridine_synthases,_methylases_and_PSUSs_PUBMED:11295541._The_THUMP_domain_consists_of_about_110_amino_acid_residues._The_structure_of_ThiI_reveals_that_the_THUMP_has_a_fold_unlike_that_of_previously_...

description:
  The THUMP domain is named after after thiouridine synthases, methylases and PSUSs PUBMED:11295541. The THUMP domain consists of about 110 amino acid residues. The structure of ThiI reveals that the THUMP has a fold unlike that of previously ...


id: SM00985
description: Ubiquitin-activating enzyme e1 C-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00985
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00985_Ubiquitin-activating_enzyme_e1_C-terminal_domain


id: SM00987
description: UreE urease accessory protein, C-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00987
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00987_UreE_urease_accessory_protein,_C-terminal_domain


id: SM00990
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00990
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00990_This_entry_contains_proteins_with_the_VRR-NUC_domain._It_is_associated_with_members_of_the_PD-(D/E)XK_nuclease_superfamily,_which_include_the_type_III_restriction_modification_enzymes,_for_example_StyLTI.

description:
  This entry contains proteins with the VRR-NUC domain. It is associated with members of the PD-(D/E)XK nuclease superfamily, which include the type III restriction modification enzymes, for example StyLTI.


id: SM00991
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00991
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00991_A_conserved_domain_of_46_amino_acids,_called_WHEP-TRS_has_been_shown_PUBMED:1756734_to_exist_in_a_number_of_higher_eukaryote_aminoacyl-transfer_RNA_synthetases._This_domain_is_present_one_to_six_times_in_the_several_enzymes._There_are_three_copies_in_...

description:
  A conserved domain of 46 amino acids, called WHEP-TRS has been shown PUBMED:1756734 to exist in a number of higher eukaryote aminoacyl-transfer RNA synthetases. This domain is present one to six times in the several enzymes. There are three copies in ...


id: SM00992
description: Hemimethylated DNA-binding protein YccV like
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00992
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00992_Hemimethylated_DNA-binding_protein_YccV_like


id: SM00997
description: S-adenosyl-L-homocysteine hydrolase, NAD binding domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00997
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM00997_S-adenosyl-L-homocysteine_hydrolase,_NAD_binding_domain


id: SM01002
description: Alanine dehydrogenase/PNT, C-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01002
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01002_Alanine_dehydrogenase/PNT,_C-terminal_domain


id: SM01003
description: Alanine dehydrogenase/PNT, N-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01003
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01003_Alanine_dehydrogenase/PNT,_N-terminal_domain


id: SM01007
description: Class II Aldolase and Adducin N-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01007
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01007_Class_II_Aldolase_and_Adducin_N-terminal_domain


id: SM01008
description: Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01008
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01008_Aldehyde_oxidase_and_xanthine_dehydrogenase,_a/b_hammerhead_domain


id: SM01010
description: 5-AMP-activated protein kinase beta subunit, interation domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01010
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01010_5-AMP-activated_protein_kinase_beta_subunit,_interation_domain


id: SM01013
description: Anaphase promoting complex (APC) subunit 2
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01013
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01013_Anaphase_promoting_complex_(APC)_subunit_2


id: SM01017
description: Arrestin (or S-antigen), C-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01017
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01017_Arrestin_(or_S-antigen),_C-terminal_domain


id: SM01020
description: Beta2-adaptin appendage, C-terminal sub-domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01020
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01020_Beta2-adaptin_appendage,_C-terminal_sub-domain


id: SM01022
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01022
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01022_The_ASCH_domain_adopts_a_beta-barrel_fold_similar_to_that_of_the_PUA_domain._It_is_thought_to_function_as_an_RNA-binding_domain_during_coactivation,_RNA-processing_and_possibly_during_prokaryotic_translation_regulation_PUBMED:16322048.

description:
  The ASCH domain adopts a beta-barrel fold similar to that of the PUA domain. It is thought to function as an RNA-binding domain during coactivation, RNA-processing and possibly during prokaryotic translation regulation PUBMED:16322048.


id: SM01024
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01024
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01024_This_domain_is_found_at_the_N_terminal_of_the_mitochondrial_ATPase_BSC1._It_encodes_the_import_and_intramitochondrial_sorting_for_the_protein.

description:
  This domain is found at the N terminal of the mitochondrial ATPase BSC1. It encodes the import and intramitochondrial sorting for the protein.


id: SM01025
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01025
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01025_The_BEN_domain_is_found_in_diverse_animal_proteins_such_as_BANP/SMAR1,_NAC1_and_the_Drosophila_mod(mdg4)_isoform_C,_in_the_chordopoxvirus_virosomal_protein_E5R_and_in_several_proteins_of_polydnaviruses._Computational_analysis_suggests_that_the_BEN_...

description:
  The BEN domain is found in diverse animal proteins such as BANP/SMAR1, NAC1 and the Drosophila mod(mdg4) isoform C, in the chordopoxvirus virosomal protein E5R and in several proteins of polydnaviruses. Computational analysis suggests that the BEN ...


id: SM01039
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01039
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01039_The_BRICHOS_domain_is_about_100_amino_acids_long._It_is_found_in_a_variety_of_proteins_implicated_in_dementia,_respiratory_distress_and_cancer._Its_exact_function_is_unknown

description:
  The BRICHOS domain is about 100 amino acids long. It is found in a variety of proteins implicated in dementia, respiratory distress and cancer. Its exact function is unknown


id: SM01050
description: Cactus-binding C-terminus of cactin protein
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01050
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01050_Cactus-binding_C-terminus_of_cactin_protein


id: SM01051
description: Microtubule-binding calmodulin-regulated spectrin-associated
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01051
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01051_Microtubule-binding_calmodulin-regulated_spectrin-associated


id: SM01052
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01052
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01052_Cytoskeleton-associated_proteins_(CAPs)_are_involved_in_the_organisation_of_microtubules_and_transportation_of_vesicles_and_organelles_along_the_cytoskeletal_network._A_conserved_motif,_CAP-Gly,_has_been_identified_in_a_number_of_CAPs,_including_...

description:
  Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including ...


id: SM01060
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01060
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01060_Catalases_are_antioxidant_enzymes_that_catalyse_the_conversion_of_hydrogen_peroxide_to_water_and_molecular_oxygen,_serving_to_protect_cells_from_its_toxic_effects_PUBMED:11351128._Hydrogen_peroxide_is_produced_as_a_consequence_of_oxidative_cellular_...

description:
  Catalases are antioxidant enzymes that catalyse the conversion of hydrogen peroxide to water and molecular oxygen, serving to protect cells from its toxic effects PUBMED:11351128. Hydrogen peroxide is produced as a consequence of oxidative cellular ...


id: SM01072
description: Cell division protein 48 (CDC48) domain 2
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01072
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01072_Cell_division_protein_48_(CDC48)_domain_2


id: SM01073
description: Cell division protein 48 (CDC48) N-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01073
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01073_Cell_division_protein_48_(CDC48)_N-terminal_domain


id: SM01076
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01076
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01076_CG-1_domains_are_highly_conserved_domains_of_about_130_amino-acid_residues_containing_a_predicted_bipartite_NLS_and_named_after_a_partial_cDNA_clone_isolated_from_parsley_encoding_a_sequence-specific_DNA-binding_protein_PUBMED:8075408._CG-1_domains_...

description:
  CG-1 domains are highly conserved domains of about 130 amino-acid residues containing a predicted bipartite NLS and named after a partial cDNA clone isolated from parsley encoding a sequence-specific DNA-binding protein PUBMED:8075408. CG-1 domains ...


id: SM01077
description: Uncharacterized conserved protein CG6151-P
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01077
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01077_Uncharacterized_conserved_protein_CG6151-P


id: SM01083
description: N-terminal domain of CBF1 interacting co-repressor CIR
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01083
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01083_N-terminal_domain_of_CBF1_interacting_co-repressor_CIR


id: SM01084
description: Cyclin-dependent kinase regulatory subunit
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01084
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01084_Cyclin-dependent_kinase_regulatory_subunit


id: SM01086
description: C-terminal, D2-small domain, of ClpB protein
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01086
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01086_C-terminal,_D2-small_domain,_of_ClpB_protein


id: SM01089
description: Gap junction channel protein cysteine-rich domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01089
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01089_Gap_junction_channel_protein_cysteine-rich_domain


id: SM01092
description: CO dehydrogenase flavoprotein C-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01092
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01092_CO_dehydrogenase_flavoprotein_C-terminal_domain


id: SM01096
description: Carbamoyl-phosphate synthetase large chain, oligomerisation domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01096
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01096_Carbamoyl-phosphate_synthetase_large_chain,_oligomerisation_domain


id: SM01097
description: Carbamoyl-phosphate synthase small chain, CPSase domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01097
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01097_Carbamoyl-phosphate_synthase_small_chain,_CPSase_domain


id: SM01098
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01098
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01098_This_is_the_C-terminal_conserved_region_of_the_pre-mRNA_3-end-processing_of_the_polyadenylation_factor_CPSF-73/CPSF-100_proteins._The_exact_function_of_this_domain_is_not_known.

description:
  This is the C-terminal conserved region of the pre-mRNA 3-end-processing of the polyadenylation factor CPSF-73/CPSF-100 proteins. The exact function of this domain is not known.


id: SM01104
description: Spt5 C-terminal nonapeptide repeat binding Spt4
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01104
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01104_Spt5_C-terminal_nonapeptide_repeat_binding_Spt4


id: SM01109
description: The CUT domain is a DNA-binding domain often found in combination with a downstream homeodomain.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01109
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01109_The_CUT_domain_is_a_DNA-binding_domain_often_found_in_combination_with_a_downstream_homeodomain.


id: SM01115
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01115
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01115_The_cwf21_family_is_involved_in_mRNA_splicing._It_has_been_isolated_as_a_subcomplex_of_the_splicosome_in_Schizosaccharomyces_pombe_(PUBMED:11884590)._The_function_of_the_cwf21_domain_is_to_bind_directly_to_the_spliceosomal_protein_Prp8._Mutations_in_...

description:
  The cwf21 family is involved in mRNA splicing. It has been isolated as a subcomplex of the splicosome in Schizosaccharomyces pombe (PUBMED:11884590). The function of the cwf21 domain is to bind directly to the spliceosomal protein Prp8. Mutations in ...


id: SM01117
description: Cytochrome b5-like Heme/Steroid binding domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01117
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01117_Cytochrome_b5-like_Heme/Steroid_binding_domain


id: SM01118
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01118
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01118_These_sequences_are_functionally_identified_as_members_of_the_adenylate_cyclase_family,_which_catalyses_the_conversion_of_ATP_to_3,5-cyclic_AMP_and_pyrophosphate._Six_distinct_non-homologous_classes_of_AC_have_been_identified._The_structure_of_...

description:
  These sequences are functionally identified as members of the adenylate cyclase family, which catalyses the conversion of ATP to 3,5-cyclic AMP and pyrophosphate. Six distinct non-homologous classes of AC have been identified. The structure of ...


id: SM01120
description: This domain is the predicted phosphatase domain of the dihydroxyacetone kinase family.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01120
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01120_This_domain_is_the_predicted_phosphatase_domain_of_the_dihydroxyacetone_kinase_family.


id: SM01122
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01122
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01122_DBC1_and_it_homologs_from_diverse_eukaryotes_are_a_catalytically_inactive_version_of_the_Nudix_hydrolase_(MutT)_domain_(PUBMED:18418069)._DBC1_is_predicted_to_bind_NAD_metabolites_and_regulate_the_activity_of_SIRT1_or_related_deacetylases_by_sensing_...

description:
  DBC1 and it homologs from diverse eukaryotes are a catalytically inactive version of the Nudix hydrolase (MutT) domain (PUBMED:18418069). DBC1 is predicted to bind NAD metabolites and regulate the activity of SIRT1 or related deacetylases by sensing ...


id: SM01124
description: Lariat debranching enzyme, C-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01124
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01124_Lariat_debranching_enzyme,_C-terminal_domain


id: SM01127
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01127
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01127_The_DDHD_domain_is_180_residues_long_and_contains_four_conserved_residues_that_may_form_a_metal_binding_site._The_domain_is_named_after_these_four_residues._This_pattern_of_conservation_of_metal_binding_residues_is_often_seen_in_phosphoesterase_...

description:
  The DDHD domain is 180 residues long and contains four conserved residues that may form a metal binding site. The domain is named after these four residues. This pattern of conservation of metal binding residues is often seen in phosphoesterase ...


id: SM01128
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01128
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01128_This_is_a_family_of_proteins_of_approximately_300_residues,_found_in_plants_and_vertebrates._They_contain_a_highly_conserved_DDRGK_motif.

description:
  This is a family of proteins of approximately 300 residues, found in plants and vertebrates. They contain a highly conserved DDRGK motif.


id: SM01131
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01131
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01131_This_domain_is_often_found_adjacent_to_the_DHH_domain_PF01368_and_is_called_DHHA2_for_DHH_associated_domain._This_domain_is_diagnostic_of_DHH_subfamily_2_members_(PUBMED:9478130)._The_domain_is_about_120_residues_long_and_contains_a_conserved_DXK_...

description:
  This domain is often found adjacent to the DHH domain PF01368 and is called DHHA2 for DHH associated domain. This domain is diagnostic of DHH subfamily 2 members (PUBMED:9478130). The domain is about 120 residues long and contains a conserved DXK ...


id: SM01135
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01135
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01135_DIRP_(Domain_in_Rb-related_Pathway)_is_postulated_to_be_involved_in_the_Rb-related_pathway,_which_is_encoded_by_multiple_eukaryotic_genomes_and_is_present_in_proteins_including_lin-9_of_Caenorhabditis_elegans,_aly_of_fruit_fly_and_mustard_weed._...

description:
  DIRP (Domain in Rb-related Pathway) is postulated to be involved in the Rb-related pathway, which is encoded by multiple eukaryotic genomes and is present in proteins including lin-9 of Caenorhabditis elegans, aly of fruit fly and mustard weed. ...


id: SM01142
description: This C terminal domain is found in DOB1/SK12/helY-like DEAD box helicases [PUBMED:15112237].
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01142
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01142_This_C_terminal_domain_is_found_in_DOB1/SK12/helY-like_DEAD_box_helicases_[PUBMED:15112237].


id: SM01144
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01144
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01144_This_presumed_domain_is_found_in_bacterial_and_eukaryotic_proteins._Its_function_is_unknown._The_domain_contains_multiple_conserved_motifs_including_a_DTXW_motif_that_this_domain_has_been_named_after.

description:
  This presumed domain is found in bacterial and eukaryotic proteins. Its function is unknown. The domain contains multiple conserved motifs including a DTXW motif that this domain has been named after.


id: SM01147
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01147
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01147_Members_of_this_family_are_found_in_various_chromatin_remodelling_factors_and_transposases._Their_exact_function_is,_as_yet,_unknown.

description:
  Members of this family are found in various chromatin remodelling factors and transposases. Their exact function is, as yet, unknown.


id: SM01151
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01151
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01151_This_domain,_which_is_usually_found_tandemly_repeated,_is_found_various_receptor_co-activating_proteins.

description:
  This domain, which is usually found tandemly repeated, is found various receptor co-activating proteins.


id: SM01154
description: This family contains many hypothetical proteins.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01154
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01154_This_family_contains_many_hypothetical_proteins.


id: SM01155
description: Mitochondrial domain of unknown function (DUF1713)
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01155
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01155_Mitochondrial_domain_of_unknown_function_(DUF1713)


id: SM01156
description: Eukaryotic domain of unknown function (DUF1716)
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01156
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01156_Eukaryotic_domain_of_unknown_function_(DUF1716)


id: SM01158
description: This is a eukaryotic domain of unknown function.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01158
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01158_This_is_a_eukaryotic_domain_of_unknown_function.


id: SM01159
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01159
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01159_This_domain_is_found_on_the_epsilon_catalytic_subunit_of_DNA_polymerase._It_is_found_C_terminal_to_POLBc_(SM00486).

description:
  This domain is found on the epsilon catalytic subunit of DNA polymerase. It is found C terminal to POLBc (SM00486).


id: SM01160
description: Eukaryotic integral membrane protein (DUF1751)
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01160
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01160_Eukaryotic_integral_membrane_protein_(DUF1751)


id: SM01161
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01161
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01161_Eukaryotic_domain_of_unknown_function._This_domain_is_found_to_the_N-terminus_of_the_nucleic_acid_binding_domain.

description:
  Eukaryotic domain of unknown function. This domain is found to the N-terminus of the nucleic acid binding domain.


id: SM01162
description: This domain is always found adjacent to SMR (SM00463).
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01162
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01162_This_domain_is_always_found_adjacent_to_SMR_(SM00463).


id: SM01163
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01163
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01163_This_region_is_found_in_argonaute_[PUBMED:16216572]_proteins_and_often_co-occurs_with_BAG_(SM00264)_and_Piwi_(SM00950).

description:
  This region is found in argonaute [PUBMED:16216572] proteins and often co-occurs with BAG (SM00264) and Piwi (SM00950).


id: SM01164
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01164
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01164_This_domain_has_no_known_function._It_is_found_in_the_C-terminal_segment_of_various_vasopressin_receptors.

description:
  This domain has no known function. It is found in the C-terminal segment of various vasopressin receptors.


id: SM01165
description: This domain, found in Synaptojanin, has no known function.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01165
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01165_This_domain,_found_in_Synaptojanin,_has_no_known_function.


id: SM01166
description: This set of domains is found in various eukaryotic proteins. Function is unknown.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01166
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01166_This_set_of_domains_is_found_in_various_eukaryotic_proteins._Function_is_unknown.


id: SM01167
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01167
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01167_This_domain_is_predominantly_found_in_the_structural_protein_coronin,_and_is_duplicated_in_some_sequences._It_has_no_known_function_[PUBMED:16172398].

description:
  This domain is predominantly found in the structural protein coronin, and is duplicated in some sequences. It has no known function [PUBMED:16172398].


id: SM01168
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01168
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01168_The_structure_of_this_domain_displays_an_alpha-beta-beta-alpha_four_layer_topology,_with_an_HxHxxxxxxxxxH_motif_that_coordinates_a_zinc_ion,_and_an_acetate_anion_at_a_site_that_likely_supports_the_enzymatic_activity_of_an_ester_hydrolase_...

description:
  The structure of this domain displays an alpha-beta-beta-alpha four layer topology, with an HxHxxxxxxxxxH motif that coordinates a zinc ion, and an acetate anion at a site that likely supports the enzymatic activity of an ester hydrolase ...


id: SM01169
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01169
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01169_Members_of_this_family_adopt_a_structure_consisting_of_several_large_open_beta-sheets._Their_exact_function_has_not,_as_yet,_been_determined_[PUBMED:12135361].

description:
  Members of this family adopt a structure consisting of several large open beta-sheets. Their exact function has not, as yet, been determined [PUBMED:12135361].


id: SM01173
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01173
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01173_This_family_is_found_at_the_very_C-terminus_of_proteins_that_carry_a_G-patch_domain_SM00443._The_domain_is_short_and_cysteine-rich_.

description:
  This family is found at the very C-terminus of proteins that carry a G-patch domain SM00443. The domain is short and cysteine-rich .


id: SM01174
description: The proteins in this family are uncharacterized but often named FAM188B.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01174
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01174_The_proteins_in_this_family_are_uncharacterized_but_often_named_FAM188B.


id: SM01175
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01175
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01175_This_is_a_family_of_cysteine-rich_proteins._Many_members_also_carry_a_pleckstrin-homology_domain,SM00233.

description:
  This is a family of cysteine-rich proteins. Many members also carry a pleckstrin-homology domain,SM00233.


id: SM01176
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01176
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01176_This_domain_is_found_at_the_C-terminus_of_chromodomain-helicase-DNA-binding_proteins._The_exact_function_of_the_domain_is_undetermined.

description:
  This domain is found at the C-terminus of chromodomain-helicase-DNA-binding proteins. The exact function of the domain is undetermined.


id: SM01177
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01177
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01177_This_short_domain_is_found_in_fungi,_plants_and_animals,_and_the_proteins_appear_to_be_necessary_for_chromosome_segregation_during_meiosis.

description:
  This short domain is found in fungi, plants and animals, and the proteins appear to be necessary for chromosome segregation during meiosis.


id: SM01178
description: This short domain is found at the C-terminus of many helicase proteins.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01178
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01178_This_short_domain_is_found_at_the_C-terminus_of_many_helicase_proteins.


id: SM01181
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01181
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01181_E1_and_E2_enzymes_play_a_central_role_in_ubiquitin_and_ubiquitin-like_protein_transfer_cascades._This_is_an_E2_binding_domain_that_is_found_on_NEDD8_activating_E1_enzyme._The_domain_resembles_ubiquitin,_and_recruits_the_catalytic_core_of_the_E2_...

description:
  E1 and E2 enzymes play a central role in ubiquitin and ubiquitin-like protein transfer cascades. This is an E2 binding domain that is found on NEDD8 activating E1 enzyme. The domain resembles ubiquitin, and recruits the catalytic core of the E2 ...


id: SM01182
description: Eukaryotic elongation factor 1 beta central acidic region
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01182
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01182_Eukaryotic_elongation_factor_1_beta_central_acidic_region


id: SM01183
description: Elongation factor 1 gamma, conserved domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01183
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01183_Elongation_factor_1_gamma,_conserved_domain


id: SM01188
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01188
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01188_This_domain_is_required_for_the_nuclear_localisation_of_these_proteins_PUBMED:11352458._All_of_these_proteins_are_members_of_the_Tale/Knox_homeodomain_family,_a_subfamily_within_homeobox_SM00389.

description:
  This domain is required for the nuclear localisation of these proteins PUBMED:11352458. All of these proteins are members of the Tale/Knox homeodomain family, a subfamily within homeobox SM00389.


id: SM01189
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01189
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01189_The_ELM2_(Egl-27_and_MTA1_homology_2)_domain_is_a_small_domain_of_unknown_function._It_is_found_in_the_MTA1_protein_that_is_part_of_the_NuRD_complex_PUBMED:10226007._The_domain_is_usually_found_to_the_N_terminus_of_a_myb-like_DNA_binding_domain_SANT_...

description:
  The ELM2 (Egl-27 and MTA1 homology 2) domain is a small domain of unknown function. It is found in the MTA1 protein that is part of the NuRD complex PUBMED:10226007. The domain is usually found to the N terminus of a myb-like DNA binding domain SANT ...


id: SM01191
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01191
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01191_This_presumed_domain_is_named_after_Emsy_N_Terminus_(ENT)._Emsy_is_a_protein_that_is_amplified_in_breast_cancer_and_interacts_with_BRCA2._The_N_terminus_of_this_protein_is_found_to_be_similar_to_other_vertebrate_and_plant_proteins_of_unknown_...

description:
  This presumed domain is named after Emsy N Terminus (ENT). Emsy is a protein that is amplified in breast cancer and interacts with BRCA2. The N terminus of this protein is found to be similar to other vertebrate and plant proteins of unknown ...


id: SM01194
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01194
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01194_The_release_factor_eRF1_terminates_protein_biosynthesis_by_recognising_stop_codons_at_the_A_site_of_the_ribosome_and_stimulating_peptidyl-tRNA_bond_hydrolysis_at_the_peptidyl_transferase_centre._The_crystal_structure_of_human_eRF1_is_known_...

description:
  The release factor eRF1 terminates protein biosynthesis by recognising stop codons at the A site of the ribosome and stimulating peptidyl-tRNA bond hydrolysis at the peptidyl transferase centre. The crystal structure of human eRF1 is known ...


id: SM01199
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01199
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01199_The_FDF_domain,_so_called_because_of_the_conserved_FDF_at_its_N_termini,_is_an_entirely_alpha-helical_domain_with_multiple_exposed_hydrophilic_loops._It_is_found_at_the_C_terminus_of_Scd6p-like_SM_domains._It_is_also_found_with_other_divergent_Sm_...

description:
  The FDF domain, so called because of the conserved FDF at its N termini, is an entirely alpha-helical domain with multiple exposed hydrophilic loops. It is found at the C terminus of Scd6p-like SM domains. It is also found with other divergent Sm ...


id: SM01200
description: This is central domain A in proteins of the Ferlin family. PMID: 15112237
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01200
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01200_This_is_central_domain_A_in_proteins_of_the_Ferlin_family._PMID:_15112237


id: SM01201
description: This is central domain B in proteins of the Ferlin family. PMID: 15112237
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01201
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01201_This_is_central_domain_B_in_proteins_of_the_Ferlin_family._PMID:_15112237


id: SM01202
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01202
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01202_This_domain_is_present_in_proteins_of_the_Ferlin_family._It_is_often_located_between_two_C2_domains_PMID:15112237_.

description:
  This domain is present in proteins of the Ferlin family. It is often located between two C2 domains PMID:15112237 .


id: SM01203
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01203
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01203_This_domain_is_found_in_eukaryotes._This_domain_is_typically_between_135_and_149_amino_acids_in_length_and_is_found_associated_with_the_CH_domain.

description:
  This domain is found in eukaryotes. This domain is typically between 135 and 149 amino acids in length and is found associated with the CH domain.


id: SM01204
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01204
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01204_The_FIST_C_domain_is_a_novel_sensory_domain,_which_is_present_in_signal_transduction_proteins_from_Bacteria,_Archaea_and_Eukarya._Chromosomal_proximity_of_FIST-encoding_genes_to_those_coding_for_proteins_involved_in_amino_acid_metabolism_and_...

description:
  The FIST C domain is a novel sensory domain, which is present in signal transduction proteins from Bacteria, Archaea and Eukarya. Chromosomal proximity of FIST-encoding genes to those coding for proteins involved in amino acid metabolism and ...


id: SM01209
description: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01209
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01209_Phosphoribosylglycinamide_synthetase,_ATP-grasp_(A)_domain


id: SM01210
description: Phosphoribosylglycinamide synthetase, C domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01210
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01210_Phosphoribosylglycinamide_synthetase,_C_domain


id: SM01211
description: CobB/CobQ-like glutamine amidotransferase domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01211
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01211_CobB/CobQ-like_glutamine_amidotransferase_domain


id: SM01214
description: RNA pol II promoter Fmp27 protein domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01214
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01214_RNA_pol_II_promoter_Fmp27_protein_domain


id: SM01218
description: C-terminal duplication domain of Friend of PRMT1
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01218
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01218_C-terminal_duplication_domain_of_Friend_of_PRMT1


id: SM01220
description: Fragile site-associated protein C-terminus
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01220
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01220_Fragile_site-associated_protein_C-terminus


id: SM01222
description: Formiminotransferase domain, N-terminal subdomain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01222
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01222_Formiminotransferase_domain,_N-terminal_subdomain


id: SM01225
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01225
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01225_This_domain_is_found_in_disease_proteins_PKHD1_and_KIAA1199_and_is_named_G8_after_its_8_conserved_glycines._It_is_predicted_to_contain_10_beta_strands_and_an_alpha_helix.

description:
  This domain is found in disease proteins PKHD1 and KIAA1199 and is named G8 after its 8 conserved glycines. It is predicted to contain 10 beta strands and an alpha helix.


id: SM01229
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01229
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01229_This_is_the_proline-rich_region_of_metabotropic_glutamate_receptor_proteins_that_binds_Homer-related_synaptic_proteins._The_Homer_proteins_form_a_physical_tether_linking_mGluRs_with_the_inositol_trisphosphate_receptors_(IP3R)_that_appears_to_be_due_...

description:
  This is the proline-rich region of metabotropic glutamate receptor proteins that binds Homer-related synaptic proteins. The Homer proteins form a physical tether linking mGluRs with the inositol trisphosphate receptors (IP3R) that appears to be due ...


id: SM01232
description: Formamidopyrimidine-DNA glycosylase H2TH domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01232
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01232_Formamidopyrimidine-DNA_glycosylase_H2TH_domain


id: SM01237
description: Islet cell autoantigen ICA69, C-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01237
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01237_Islet_cell_autoantigen_ICA69,_C-terminal_domain


id: SM01240
description: IMP dehydrogenase / GMP reductase domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01240
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01240_IMP_dehydrogenase_/_GMP_reductase_domain


id: SM01241
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01241
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01241_Integrins_are_a_group_of_transmembrane_proteins_which_function_as_extracellular_matrix_receptors_and_in_cell_adhesion._Integrins_are_ubiquitously_expressed_and_are_heterodimeric,_each_composed_of_an_alpha_and_beta_subunit._Several_variations_of_the_...

description:
  Integrins are a group of transmembrane proteins which function as extracellular matrix receptors and in cell adhesion. Integrins are ubiquitously expressed and are heterodimeric, each composed of an alpha and beta subunit. Several variations of the ...


id: SM01242
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01242
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01242_This_is_the_beta_tail_domain_of_the_Integrin_protein._Integrins_are_receptors_which_are_involved_in_cell-cell_and_cell-extracellular_matrix_interactions.

description:
  This is the beta tail domain of the Integrin protein. Integrins are receptors which are involved in cell-cell and cell-extracellular matrix interactions.


id: SM01253
description: Domain of Kin17 curved DNA-binding protein
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01253
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01253_Domain_of_Kin17_curved_DNA-binding_protein


id: SM01257
description: Ki-ras-induced actin-interacting protein-IP3R-interacting domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01257
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01257_Ki-ras-induced_actin-interacting_protein-IP3R-interacting_domain


id: SM01261
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01261
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01261_Short_protein_of_49_amino_acid_isolated_from_bovine_spleen_cells_PUBMED:7306506._Thymopoietins_(TMPOs)_are_a_group_of_ubiquitously_expressed_nuclear_proteins._They_are_suggested_to_play_an_important_role_in_nuclear_envelope_organisation_and_cell_...

description:
  Short protein of 49 amino acid isolated from bovine spleen cells PUBMED:7306506. Thymopoietins (TMPOs) are a group of ubiquitously expressed nuclear proteins. They are suggested to play an important role in nuclear envelope organisation and cell ...


id: SM01262
description: Late endosomal/lysosomal adaptor and MAPK and MTOR activator
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01262
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01262_Late_endosomal/lysosomal_adaptor_and_MAPK_and_MTOR_activator


id: SM01265
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01265
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01265_This_family_contains_Mab-21_and_Mab-21_like_proteins._In_C._elegans_these_proteins_are_required_for_several_aspects_of_embryonic_development_PUBMED:8582275

description:
  This family contains Mab-21 and Mab-21 like proteins. In C. elegans these proteins are required for several aspects of embryonic development PUBMED:8582275


id: SM01272
description: This domain is found associated with Lsm domain PMID:16115810.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01272
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01272_This_domain_is_found_associated_with_Lsm_domain_PMID:16115810.


id: SM01277
description: Polyubiquitination (PEST) N-terminal domain of MAGUK
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01277
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01277_Polyubiquitination_(PEST)_N-terminal_domain_of_MAGUK


id: SM01278
description: Mitogen-activated protein kinase kinase 1 interacting
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01278
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01278_Mitogen-activated_protein_kinase_kinase_1_interacting


id: SM01279
description: Trimeric coiled-coil oligomerisation domain of matrilin
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01279
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01279_Trimeric_coiled-coil_oligomerisation_domain_of_matrilin


id: SM01281
description: Transcription mediator complex subunit Med12
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01281
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01281_Transcription_mediator_complex_subunit_Med12


id: SM01283
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01283
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01283_This_domain_is_found_both_alone_and_at_the_C-terminus_of_actin-binding_Rho-activating_protein_(ABRA)._It_binds_to_actin,_and_in_muscle_regulates_the_actin_cytoskeleton_and_cell_motility_PMID:11983702,_20940261._It_has_a_winged_helix-like_fold_...

description:
  This domain is found both alone and at the C-terminus of actin-binding Rho-activating protein (ABRA). It binds to actin, and in muscle regulates the actin cytoskeleton and cell motility PMID:11983702, 20940261. It has a winged helix-like fold ...


id: SM01285
description: FACT complex subunit SPT16 N-terminal lobe domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01285
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01285_FACT_complex_subunit_SPT16_N-terminal_lobe_domain


id: SM01291
description: COMPASS (Complex proteins associated with Set1p) component N
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01291
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01291_COMPASS_(Complex_proteins_associated_with_Set1p)_component_N


id: SM01296
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01296
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01296_This_family_features_sequences_that_are_similar_to_a_region_of_hypothetical_yeast_gene_product_N2227._This_is_thought_to_be_expressed_during_meiosis_and_may_be_involved_in_the_defence_response_to_stressful_conditions_PMID:8771715.

description:
  This family features sequences that are similar to a region of hypothetical yeast gene product N2227. This is thought to be expressed during meiosis and may be involved in the defence response to stressful conditions PMID:8771715.


id: SM01300
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01300
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01300_This_domain_was_first_identified_in_drosophila_MSL1_(male-specific_lethal_1)_PMID:12698291._In_drosophila_it_binds_to_the_histone_acetyltransferase_males-absent_on_the_first_protein_(MOF)_and_to_protein_male-specific_lethal-3_(MSL3)_PMID:15141166

description:
  This domain was first identified in drosophila MSL1 (male-specific lethal 1) PMID:12698291. In drosophila it binds to the histone acetyltransferase males-absent on the first protein (MOF) and to protein male-specific lethal-3 (MSL3) PMID:15141166


id: SM01303
description: Rapamycin-insensitive companion of mTOR RasGEF_N domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01303
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01303_Rapamycin-insensitive_companion_of_mTOR_RasGEF_N_domain


id: SM01305
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01305
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01305_This_domain_is_found_in_the_glucocorticoid-responsive_protein_regulated_endocrine-specific_protein_18_(RESP18)_and_in_the_N-terminal_extracellular_region_of_receptor-type_tyrosine-protein_phosphatases_containing_the_protein-tyrosine_phosphatase_...

description:
  This domain is found in the glucocorticoid-responsive protein regulated endocrine-specific protein 18 (RESP18) and in the N-terminal extracellular region of receptor-type tyrosine-protein phosphatases containing the protein-tyrosine phosphatase ...


id: SM01307
description: Rapamycin-insensitive companion of mTOR, middle domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01307
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01307_Rapamycin-insensitive_companion_of_mTOR,_middle_domain


id: SM01308
description: Rapamycin-insensitive companion of mTOR, N-term
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01308
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01308_Rapamycin-insensitive_companion_of_mTOR,_N-term


id: SM01309
description: Rapamycin-insensitive companion of mTOR, phosphorylation-site
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01309
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01309_Rapamycin-insensitive_companion_of_mTOR,_phosphorylation-site


id: SM01310
description: Rapamycin-insensitive companion of mTOR, domain 5
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01310
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01310_Rapamycin-insensitive_companion_of_mTOR,_domain_5


id: SM01313
description: Exocyst complex component SEC3 N-terminal PIP2 binding PH
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01313
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01313_Exocyst_complex_component_SEC3_N-terminal_PIP2_binding_PH


id: SM01314
description: Snf2-ATP coupling, chromatin remodelling complex
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01314
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01314_Snf2-ATP_coupling,_chromatin_remodelling_complex


id: SM01319
description: Tankyrase binding protein C terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01319
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01319_Tankyrase_binding_protein_C_terminal_domain


id: SM01326
description: C2 domain of PTEN tumour-suppressor protein
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01326
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01326_C2_domain_of_PTEN_tumour-suppressor_protein


id: SM01329
description: Isocitrate/isopropylmalate dehydrogenase
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01329
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01329_Isocitrate/isopropylmalate_dehydrogenase


id: SM01330
description: Frizzled/Smoothened family membrane region
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01330
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01330_Frizzled/Smoothened_family_membrane_region


id: SM01332
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01332
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01332_Cyclins_are_a_family_of_proteins_that_control_the_progression_of_cells_through_the_cell_cycle_by_activating_cyclin-dependent_kinase_(Cdk)_enzymes.

description:
  Cyclins are a family of proteins that control the progression of cells through the cell cycle by activating cyclin-dependent kinase (Cdk) enzymes.


id: SM01333
description: Oxygenase domain of the 2OGFeDO superfamily
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01333
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01333_Oxygenase_domain_of_the_2OGFeDO_superfamily


id: SM01335
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01335
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01335_This_domain_is_found_in_poly(ADP-ribose)-synthetases_(PMID:15112237)._The_function_of_this_domain_is_unknown.

description:
  This domain is found in poly(ADP-ribose)-synthetases (PMID:15112237). The function of this domain is unknown.


id: SM01336
description: Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01336
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01336_Poly(ADP-ribose)_polymerase_and_DNA-Ligase_Zn-finger_region


id: SM01337
description: Anaphase-promoting complex, subunit 10 (APC10)
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01337
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01337_Anaphase-promoting_complex,_subunit_10_(APC10)


id: SM01338
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01338
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01338_NOTCH_signalling_plays_a_fundamental_role_during_a_great_number_of_developmental_processes_in_multicellular_animals_(PMID:10221902,_11112321)._NOD_and_NODP_represent_a_region_present_in_many_NOTCH_proteins_and_NOTCH_homologs_in_multiple_species_such_...

description:
  NOTCH signalling plays a fundamental role during a great number of developmental processes in multicellular animals (PMID:10221902, 11112321). NOD and NODP represent a region present in many NOTCH proteins and NOTCH homologs in multiple species such ...


id: SM01339
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01339
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01339_NOTCH_signalling_plays_a_fundamental_role_during_a_great_number_of_developmental_processes_in_multicellular_animals_(PMID:10221902,_11112321)._NOD_and_NODP_represent_a_region_present_in_many_NOTCH_proteins_and_NOTCH_homologs_in_multiple_species_such_...

description:
  NOTCH signalling plays a fundamental role during a great number of developmental processes in multicellular animals (PMID:10221902, 11112321). NOD and NODP represent a region present in many NOTCH proteins and NOTCH homologs in multiple species such ...


id: SM01340
description: DNA mismatch repair protein, C-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01340
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01340_DNA_mismatch_repair_protein,_C-terminal_domain


id: SM01341
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01341
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01341_Members_of_this_family_adopt_a_secondary_structure_consisting_of_a_pair_of_long,_antiparallel_alpha-helices_(the_stem)_that_support_a_three-helix_bundle_(3HB)_at_their_end._The_3HB_contains_a_helix-turn-helix_motif_and_is_similar_to_the_DNA_binding_...

description:
  Members of this family adopt a secondary structure consisting of a pair of long, antiparallel alpha-helices (the stem) that support a three-helix bundle (3HB) at their end. The 3HB contains a helix-turn-helix motif and is similar to the DNA binding ...


id: SM01342
description: Telomere-length maintenance and DNA damage repair
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01342
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01342_Telomere-length_maintenance_and_DNA_damage_repair


id: SM01343
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01343
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01343_The_FATC_domain_is_named_after_FRAP,_ATM,_TRRAP_C-terminal_(PMID:10782091)._The_solution_structure_of_the_FATC_domain_suggests_it_plays_a_role_in_redox-dependent_structural_and_cellular_stability_(PMID:15772072).

description:
  The FATC domain is named after FRAP, ATM, TRRAP C-terminal (PMID:10782091). The solution structure of the FATC domain suggests it plays a role in redox-dependent structural and cellular stability (PMID:15772072).


id: SM01344
description: This is domain B in the catalytic subunit of DNA-dependent protein kinases.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01344
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01344_This_is_domain_B_in_the_catalytic_subunit_of_DNA-dependent_protein_kinases.


id: SM01349
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01349
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01349_XMAP215/Dis1_proteins,_such_as_Alp14_and_XMAP215,_increase_microtubules_dynamic_polymerization_rates_by_recruiting_soluble_αβ-tubulin_via_their_conserved_TOG_domains_to_polymerizing_microtubule_plus_ends.

description:
  XMAP215/Dis1 proteins, such as Alp14 and XMAP215, increase microtubules dynamic polymerization rates by recruiting soluble αβ-tubulin via their conserved TOG domains to polymerizing microtubule plus ends.


id: SM01350
description: 6-phosphogluconate dehydrogenase, C-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01350
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01350_6-phosphogluconate_dehydrogenase,_C-terminal_domain


id: SM01352
description: Adenomatosis polyposis coli down-regulated 1
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01352
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01352_Adenomatosis_polyposis_coli_down-regulated_1


id: SM01353
description: Apoptosis-inducing factor, mitochondrion-associated, C-term
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01353
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01353_Apoptosis-inducing_factor,_mitochondrion-associated,_C-term


id: SM01355
description: Clathrin-adaptor complex-3 beta-1 subunit C-terminal
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01355
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01355_Clathrin-adaptor_complex-3_beta-1_subunit_C-terminal


id: SM01356
description: Adaptin AP4 complex epsilon appendage platform
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01356
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01356_Adaptin_AP4_complex_epsilon_appendage_platform


id: SM01366
description: Sequence-specific DNA binding domain in TCFs.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01366
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01366_Sequence-specific_DNA_binding_domain_in_TCFs.


id: SM01368
description: Retinoblastoma-associated protein A domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01368
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01368_Retinoblastoma-associated_protein_A_domain


id: SM01371
description: Transcription factor IIA, alpha/beta subunit
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01371
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01371_Transcription_factor_IIA,_alpha/beta_subunit


id: SM01372
description: E2F/DP family winged-helix DNA-binding domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01372
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01372_E2F/DP_family_winged-helix_DNA-binding_domain


id: SM01376
description: Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01376
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01376_Eukaryotic_elongation_factor_5A_hypusine,_DNA-binding_OB_fold


id: SM01378
description: Reactive mitochondrial oxygen species modulator 1
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01378
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01378_Reactive_mitochondrial_oxygen_species_modulator_1


id: SM01379
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01379
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01379_This_family_consists_of_several_GAGE_and_XAGE_proteins_which_are_found_exclusively_in_humans._The_function_of_this_family_is_unknown_although_they_have_been_implicated_in_human_cancers_(PMID:11992404)

description:
  This family consists of several GAGE and XAGE proteins which are found exclusively in humans. The function of this family is unknown although they have been implicated in human cancers (PMID:11992404)


id: SM01382
description: Ribosomal Proteins L2, C-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01382
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01382_Ribosomal_Proteins_L2,_C-terminal_domain


id: SM01383
description: Ribosomal Proteins L2, RNA binding domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01383
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01383_Ribosomal_Proteins_L2,_RNA_binding_domain


id: SM01385
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01385
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01385_This_family_contains_the_breast_cancer_tumour_suppressor_BRCA2-interacting_protein_DSS1_and_its_homologue_SEM1,_both_of_which_are_short_acidic_proteins._DSS1_has_been_shown_to_be_a_conserved_component_of_the_Rae1_mediated_mRNA_export_pathway_in_...

description:
  This family contains the breast cancer tumour suppressor BRCA2-interacting protein DSS1 and its homologue SEM1, both of which are short acidic proteins. DSS1 has been shown to be a conserved component of the Rae1 mediated mRNA export pathway in ...


id: SM01390
description: Ribosomal protein S4/S9 N-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01390
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01390_Ribosomal_protein_S4/S9_N-terminal_domain


id: SM01393
description: This family includes ribosomal protein L32 from eukaryotes and archaebacteria.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01393
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01393_This_family_includes_ribosomal_protein_L32_from_eukaryotes_and_archaebacteria.


id: SM01395
description: Transcription factor TFIIH complex subunit Tfb5
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01395
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01395_Transcription_factor_TFIIH_complex_subunit_Tfb5


id: SM01400
description: N-terminal domain of ribose phosphate pyrophosphokinase
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01400
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01400_N-terminal_domain_of_ribose_phosphate_pyrophosphokinase


id: SM01404
description: Cation-independent mannose-6-phosphate receptor repeat
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01404
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01404_Cation-independent_mannose-6-phosphate_receptor_repeat


id: SM01406
description: Family of proteins with a conserved region found in PAPA-1, a PAP-1 binding protein.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01406
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01406_Family_of_proteins_with_a_conserved_region_found_in_PAPA-1,_a_PAP-1_binding_protein.


id: SM01408
description: Inhibitor of growth proteins N-terminal histone-binding
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01408
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01408_Inhibitor_of_growth_proteins_N-terminal_histone-binding


id: SM01419
description: Alpha-macro-globulin thiol-ester bond-forming region
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01419
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01419_Alpha-macro-globulin_thiol-ester_bond-forming_region


id: SM01422
description: Smad anchor for receptor activation (SARA)
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01422
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01422_Smad_anchor_for_receptor_activation_(SARA)


id: SM01477
description: DDE transposase retroviral integrase sub-family
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01477
name:
  Protein Domains (SMART).STRING_v12.0_64176_STRINGid_SM01477_DDE_transposase_retroviral_integrase_sub-family


