# geneInfo

ensembl_gene_id: TOL2_C00010
symbol: dnaN
gene_biotype: protein_coding
description:
  DnaN: DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiatio [...]


ensembl_gene_id: TOL2_C00020
symbol: gyrB
gene_biotype: protein_coding
description:
  GyrB: DNA gyrase, subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.


ensembl_gene_id: TOL2_C00080
symbol: cbiA
gene_biotype: protein_coding
description:
  CbiA: hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.


ensembl_gene_id: TOL2_C00090
symbol: cbiD
gene_biotype: protein_coding
description:
  CbiD: putative cobalt-precorrin-6A synthase; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.


ensembl_gene_id: TOL2_C00230
symbol: pncB
gene_biotype: protein_coding
description:
  PncB: Nicotinate phosphoribosyltransferase (NAPRTase); Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family.


ensembl_gene_id: TOL2_C00270
symbol: CCK78197.1
gene_biotype: protein_coding
description:
  Putative short chain dehydrogenase/reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: TOL2_C00430
symbol: aor1
gene_biotype: protein_coding
description:
  Aor1: tungsten-containing aldehyde:ferredoxin oxidoreductase, predicted function in phenylacetaldehyde oxidation.


ensembl_gene_id: TOL2_C00490
symbol: nfo
gene_biotype: protein_coding
description:
  Nfo: endonuclease 4; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.


ensembl_gene_id: TOL2_C00560
symbol: thiC
gene_biotype: protein_coding
description:
  ThiC: thiamine biosynthesis protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.


ensembl_gene_id: TOL2_C00570
symbol: thiE
gene_biotype: protein_coding
description:
  Thiamine-phosphate synthase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.


ensembl_gene_id: TOL2_C00600
symbol: thiG
gene_biotype: protein_coding
description:
  ThiG: thiazole biosynthesis family protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.


ensembl_gene_id: TOL2_C00630
symbol: bamD
gene_biotype: protein_coding
description:
  Putative DNA uptake lipoprotein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: TOL2_C01030
symbol: ogt
gene_biotype: protein_coding
description:
  Ogt: methylated-DNA--protein-cysteine methyltransferase (6-o-methylguanine-dna methyltransferase); Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.


ensembl_gene_id: TOL2_C01080
symbol: LysA
gene_biotype: protein_coding
description:
  LysA: diaminopimelate decarboxylase (DAP decarboxylase); Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine; Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.


ensembl_gene_id: TOL2_C01100
symbol: speA
gene_biotype: protein_coding
description:
  SpeA: arginine decarboxylase; Catalyzes the biosynthesis of agmatine from arginine. Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.


ensembl_gene_id: TOL2_C01290
symbol: gabT
gene_biotype: protein_coding
description:
  GabT: 4-aminobutyrate aminotransferase (Gamma-amino-N-butyrate transaminase); Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: TOL2_C01440
symbol: bbsB2
gene_biotype: protein_coding
description:
  BbsB2: benzylsuccinyl-CoA thiolase, subunit B; Belongs to the thiolase-like superfamily. Thiolase family.


ensembl_gene_id: TOL2_C01480
symbol: bbsB
gene_biotype: protein_coding
description:
  BbsB: benzylsuccinyl-CoA thiolase, subunit B; Belongs to the thiolase-like superfamily. Thiolase family.


ensembl_gene_id: TOL2_C01630
symbol: frdB1
gene_biotype: protein_coding
description:
  FrdB1: fumarate reducatse, iron-sulfur subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.


ensembl_gene_id: TOL2_C01690
symbol: fadA
gene_biotype: protein_coding
description:
  FadA: 3-ketoacyl-CoA thiolase (Beta-ketothiolase) (Acetyl-CoA acyltransferase); Belongs to the thiolase-like superfamily. Thiolase family.


ensembl_gene_id: TOL2_C02080
symbol: mrpB
gene_biotype: protein_coding
description:
  MrpB: Na(+)/H(+) antiporter, subunit B (Multiple resistance and pH homeostasis protein B); Signal peptide.


ensembl_gene_id: TOL2_C02090
symbol: mrpC
gene_biotype: protein_coding
description:
  MrpC: Na(+)/H(+) antiporter, subunit C (Multiple resistance and pH homeostasis protein C); Signal peptide.


ensembl_gene_id: TOL2_C02110
symbol: mrpE
gene_biotype: protein_coding
description:
  MrpE: Na(+)/H(+) antiporter, subunit E (Multiple resistance and pH homeostasis protein E); Signal peptide.


ensembl_gene_id: TOL2_C02120
symbol: mrpF
gene_biotype: protein_coding
description:
  MrpF: Na(+)/H(+) antiporter, subunit F (Multiple resistance and pH homeostasis protein F); Signal peptide.


ensembl_gene_id: TOL2_C02130
symbol: mrpG
gene_biotype: protein_coding
description:
  MrpG: Na(+)/H(+) antiporter, subunit G (Multiple resistance and pH homeostasis protein G); Signal peptide.


ensembl_gene_id: TOL2_C02340
symbol: padB1
gene_biotype: protein_coding
description:
  PadB1: phenylacetyl-CoA:acceptor oxidoreductase, subunit B; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: TOL2_C02410
symbol: livM
gene_biotype: protein_coding
description:
  LivM: high-affinity branched-chain amino acid transport system permease protein; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: TOL2_C02420
symbol: livH
gene_biotype: protein_coding
description:
  LivH: high-affinity branched-chain amino acid transport system permease protein; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: TOL2_C02510
symbol: CCK78421.1
gene_biotype: protein_coding
description:
  Putative mercuric reductase (Hg(II) reductase); Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.


ensembl_gene_id: TOL2_C02550
symbol: proC
gene_biotype: protein_coding
description:
  ProC: pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.


ensembl_gene_id: TOL2_C02620
symbol: iscS
gene_biotype: protein_coding
description:
  IscS: cysteine desulfurase; Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.


ensembl_gene_id: TOL2_C02670
symbol: clpB
gene_biotype: protein_coding
description:
  ClpB: chaperone; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.


ensembl_gene_id: TOL2_C02810
symbol: CCK78451.1
gene_biotype: protein_coding
description:
  Methylenetetrahydrofolate reductase domain protein; Belongs to the methylenetetrahydrofolate reductase family.


ensembl_gene_id: TOL2_C02870
symbol: iorA
gene_biotype: protein_coding
description:
  IorA: indolepyruvate oxidoreductase subunit A; Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.


ensembl_gene_id: TOL2_C02910
symbol: pyrE
gene_biotype: protein_coding
description:
  PyrE: orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).


ensembl_gene_id: TOL2_C03010
symbol: dapL
gene_biotype: protein_coding
description:
  DapL: LL-diaminopimelate aminotransferase (LL-DAP-aminotransferase); Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL- diaminopimelate.


ensembl_gene_id: TOL2_C03020
symbol: moaE
gene_biotype: protein_coding
description:
  MoaE: molybdopterin biosynthesis protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.


ensembl_gene_id: TOL2_C03030
symbol: moeA
gene_biotype: protein_coding
description:
  MoeA: molybdopterin biosynthesis protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.


ensembl_gene_id: TOL2_C03060
symbol: uppP
gene_biotype: protein_coding
description:
  UppP: Undecaprenyl-diphosphatase (Bacitracin resistance protein); Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.


ensembl_gene_id: TOL2_C03120
symbol: speE
gene_biotype: protein_coding
description:
  SpeE: predicted spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.


ensembl_gene_id: TOL2_C03360
symbol: trpB
gene_biotype: protein_coding
description:
  TrpB: tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.


ensembl_gene_id: TOL2_C03420
symbol: radA
gene_biotype: protein_coding
description:
  RadA: DNA repair protein radA homolog; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.


ensembl_gene_id: TOL2_C03430
symbol: rrmJ
gene_biotype: protein_coding
description:
  RrmJ: ribosomal RNA large subunit methyltransferase J (23S rRNA methylase); Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.


ensembl_gene_id: TOL2_C03450
symbol: nadA
gene_biotype: protein_coding
description:
  NadA: Quinolinate synthetase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.


ensembl_gene_id: TOL2_C03460
symbol: lolA
gene_biotype: protein_coding
description:
  LolA: predicted outer membrane lipoprotein carrier protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).


ensembl_gene_id: TOL2_C03490
symbol: grpE
gene_biotype: protein_coding
description:
  GrpE: HSP70 cofactor; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dep [...]


ensembl_gene_id: TOL2_C03540
symbol: fieF
gene_biotype: protein_coding
description:
  FieF: predicte cation-efflux pump; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.


ensembl_gene_id: TOL2_C03570
symbol: ilvY
gene_biotype: protein_coding
description:
  IlvY: transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: TOL2_C03580
symbol: ilvC
gene_biotype: protein_coding
description:
  IlvC: ketol-acid reductoisomerase (Acetohydroxy-acid isomeroreductase); Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.


ensembl_gene_id: TOL2_C03600
symbol: truA
gene_biotype: protein_coding
description:
  TruA: tRNA pseudouridine synthase I; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.


ensembl_gene_id: TOL2_C03620
symbol: CCK78532.1
gene_biotype: protein_coding
description:
  Sulfite reductase, assimilatory type; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.


ensembl_gene_id: TOL2_C03700
symbol: bamL
gene_biotype: protein_coding
description:
  BamL: formate dehydrogenase, subunit D; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.


ensembl_gene_id: TOL2_C03810
symbol: oah
gene_biotype: protein_coding
description:
  Oah: predicted 6-oxo-cyclohex-1-ene-carbonyl-CoA hydrolase; Belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: TOL2_C03880
symbol: bamW
gene_biotype: protein_coding
description:
  BamW: two component transcriptional regulator, sigma54-specific, associated with benzoate catabolic cluster.


ensembl_gene_id: TOL2_C03960
symbol: CCK78566.1
gene_biotype: protein_coding
description:
  Predicted FAD-dependent pyridine nucleotide-disulfide oxidoreductase; Related to bzdV of A. aromatoelum EbN1.


ensembl_gene_id: TOL2_C03980
symbol: phsA
gene_biotype: protein_coding
description:
  PhsA: putative thiosulfate reductase, subunit A; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: TOL2_C04030
symbol: CCK78573.1
gene_biotype: protein_coding
description:
  Predicted efflux transporter, RND family, membrane fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: TOL2_C04040
symbol: CCK78574.1
gene_biotype: protein_coding
description:
  Predicted efflux transporter, AcrB/AcrD/AcrF family, permease; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: TOL2_C04110
symbol: dcm
gene_biotype: protein_coding
description:
  Dcm: DNA-cytosine methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.


ensembl_gene_id: TOL2_C04310
symbol: metF1
gene_biotype: protein_coding
description:
  MetF1: methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.


ensembl_gene_id: TOL2_C04360
symbol: tig
gene_biotype: protein_coding
description:
  Tig: trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.


ensembl_gene_id: TOL2_C04370
symbol: clpP
gene_biotype: protein_coding
description:
  ClpP: ATP-dependent Clp protease, proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.


ensembl_gene_id: TOL2_C04380
symbol: clpX
gene_biotype: protein_coding
description:
  ClpX: ATP-dependent Clp protease, ATP-binding subunit; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.


ensembl_gene_id: TOL2_C04390
symbol: lon
gene_biotype: protein_coding
description:
  Lon: ATP-dependent protease La 1; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.


ensembl_gene_id: TOL2_C04400
symbol: rho
gene_biotype: protein_coding
description:
  Rho: transcription termination factor rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.


ensembl_gene_id: TOL2_C04410
symbol: leuB
gene_biotype: protein_coding
description:
  LeuB: 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.


ensembl_gene_id: TOL2_C04510
symbol: CCK78620.1
gene_biotype: protein_coding
description:
  Deoxyguanosinetriphosphate triphosphohydrolase-like protein; Belongs to the dGTPase family. Type 2 subfamily.


ensembl_gene_id: TOL2_C04530
symbol: infC
gene_biotype: protein_coding
description:
  InfC: translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.


ensembl_gene_id: TOL2_C04550
symbol: rplT
gene_biotype: protein_coding
description:
  RplT: 50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.


ensembl_gene_id: TOL2_C04560
symbol: pheS
gene_biotype: protein_coding
description:
  PheS: Phenylalanyl-tRNA synthetase, alpha chain; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.


ensembl_gene_id: TOL2_C04570
symbol: pheT
gene_biotype: protein_coding
description:
  PheT: Phenylalanyl-tRNA synthetase beta chain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.


ensembl_gene_id: TOL2_C04580
symbol: rimP
gene_biotype: protein_coding
description:
  Conserved uncharacterized protein, DUF150; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.


ensembl_gene_id: TOL2_C04590
symbol: nusA
gene_biotype: protein_coding
description:
  NusA: transcription elongation protein; Participates in both transcription termination and antitermination.


ensembl_gene_id: TOL2_C04600
symbol: infB
gene_biotype: protein_coding
description:
  InfB: translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.


ensembl_gene_id: TOL2_C04610
symbol: rbfA
gene_biotype: protein_coding
description:
  RbfA: ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.


ensembl_gene_id: TOL2_C04620
symbol: truB
gene_biotype: protein_coding
description:
  TruB: tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.


ensembl_gene_id: TOL2_C04630
symbol: rpsO
gene_biotype: protein_coding
description:
  RpsO: 30S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.


ensembl_gene_id: TOL2_C04640
symbol: pnp
gene_biotype: protein_coding
description:
  Pnp: polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase); Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.


ensembl_gene_id: TOL2_C04910
symbol: bhsB
gene_biotype: protein_coding
description:
  BhsB: hydroxybenzylsuccinyl-CoA thiolase, subunit B; Belongs to the thiolase-like superfamily. Thiolase family.


ensembl_gene_id: TOL2_C05050
symbol: bssG2
gene_biotype: protein_coding
description:
  BssG2: conserved uncharacterized protein associated with anaerobic toluene degradation gene cluster.


ensembl_gene_id: TOL2_C05070
symbol: sucC
gene_biotype: protein_coding
description:
  SucC: succinyl-CoA ligase [ADP-forming], beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.


ensembl_gene_id: TOL2_C05080
symbol: sucD
gene_biotype: protein_coding
description:
  SucD: succinyl-CoA ligase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.


ensembl_gene_id: TOL2_C05110
symbol: frdB2
gene_biotype: protein_coding
description:
  FrdB2: fumarate reductase, iron-sulfur subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.


ensembl_gene_id: TOL2_C05120
symbol: fumB
gene_biotype: protein_coding
description:
  FumB: fumarate hydratase class I (fumarase); Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.


ensembl_gene_id: TOL2_C05160
symbol: fumC
gene_biotype: protein_coding
description:
  FumC: fumarate hydratase class II (fumarase C); Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.


ensembl_gene_id: TOL2_C05220
symbol: acsA
gene_biotype: protein_coding
description:
  AcsA: acetyl-coenzyme A synthetase (acetate--CoA ligase); Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.


ensembl_gene_id: TOL2_C05330
symbol: CCK78701.1
gene_biotype: protein_coding
description:
  Multidrug resistance protein, AcrB family; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: TOL2_C05360
symbol: cobT
gene_biotype: protein_coding
description:
  CobT: predicted nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).


ensembl_gene_id: TOL2_C05370
symbol: trpD
gene_biotype: protein_coding
description:
  TrpD: anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).


ensembl_gene_id: TOL2_C05540
symbol: dapA
gene_biotype: protein_coding
description:
  DapA: dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).


ensembl_gene_id: TOL2_C05590
symbol: dsrD
gene_biotype: protein_coding
description:
  DsrD: sulfite reductase, dissimilatory-type, delta subunit; Possibly involved in transcription or translation of sulfite reductase genes.


ensembl_gene_id: TOL2_C05600
symbol: cobB
gene_biotype: protein_coding
description:
  CobB: cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.


ensembl_gene_id: TOL2_C05620
symbol: tatC
gene_biotype: protein_coding
description:
  TatC: sec-independent protein translocase protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.


ensembl_gene_id: TOL2_C05640
symbol: rhlB
gene_biotype: protein_coding
description:
  RhlB: ATP-dependent RNA helicase; DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA.


ensembl_gene_id: TOL2_C05770
symbol: dus
gene_biotype: protein_coding
description:
  Dus: tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.


ensembl_gene_id: TOL2_C05790
symbol: feoB
gene_biotype: protein_coding
description:
  FeoB: ferrous iron transport protein B; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.


ensembl_gene_id: TOL2_C05920
symbol: serS
gene_biotype: protein_coding
description:
  SerC: seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).


ensembl_gene_id: TOL2_C05960
symbol: pcm
gene_biotype: protein_coding
description:
  Pcm: protein-L-isoaspartate O-methyltransferase (protein-beta-aspartate methyltransferase); Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.


ensembl_gene_id: TOL2_C06020
symbol: coaD
gene_biotype: protein_coding
description:
  CoaD: phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.


ensembl_gene_id: TOL2_C06070
symbol: lpxC
gene_biotype: protein_coding
description:
  LpxC: UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family.


ensembl_gene_id: TOL2_C06290
symbol: blc2
gene_biotype: protein_coding
description:
  Blc2: outer membrane transporter, lipocalin family; Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.


ensembl_gene_id: TOL2_C06420
symbol: qhpX
gene_biotype: protein_coding
description:
  QhpX: predicted quinohemoprotein amine dehydrogenase, putative SAM-radical dependent activating subunit.


ensembl_gene_id: TOL2_C06660
symbol: apbE
gene_biotype: protein_coding
description:
  ApbE: thiamin biosynthesis lipoprotein; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. Belongs to the ApbE family.


ensembl_gene_id: TOL2_C06760
symbol: mcmL
gene_biotype: protein_coding
description:
  McmL: methylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.


ensembl_gene_id: TOL2_C06770
symbol: atoB
gene_biotype: protein_coding
description:
  AtoB: acetyl-CoA acetyltransferase (acetoacetyl-CoA thiolase); Belongs to the thiolase-like superfamily. Thiolase family.


ensembl_gene_id: TOL2_C06810
symbol: CCK78850.1
gene_biotype: protein_coding
description:
  Uncharacterized response regulator receiver domain protein combined with universal stress protein domain.


ensembl_gene_id: TOL2_C06840
symbol: livM2
gene_biotype: protein_coding
description:
  LivM2: branched-chain amino acid ABC transporter, permease protein; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: TOL2_C06850
symbol: livH2
gene_biotype: protein_coding
description:
  LivH2: branched-chain amino acid ABC transport system permease protein; Signal anchor; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: TOL2_C06930
symbol: tdh
gene_biotype: protein_coding
description:
  Tdh: L-threonine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family.


ensembl_gene_id: TOL2_C07170
symbol: korD
gene_biotype: protein_coding
description:
  KorD: 2-oxoglutarate ferredoxin oxidoreductase, delta subunit (2-ketoglutarate oxidoreductase delta chain).


ensembl_gene_id: TOL2_C07270
symbol: ribB
gene_biotype: protein_coding
description:
  RibB: 3,4-dihydroxy-2-butanone 4-phosphate synthase (DHBP synthase); Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.


ensembl_gene_id: TOL2_C07290
symbol: hypF
gene_biotype: protein_coding
description:
  HypF: hydrogenase maturation factor; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.


ensembl_gene_id: TOL2_C07340
symbol: crcB
gene_biotype: protein_coding
description:
  CrcB: predicted intefral membrane protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.


ensembl_gene_id: TOL2_C07360
symbol: CCK78904.1
gene_biotype: protein_coding
description:
  Conserved uncharacterized protein, possibly involved in regulation of phenolics degradation; Signal peptide.


ensembl_gene_id: TOL2_C07460
symbol: aroF
gene_biotype: protein_coding
description:
  AroF: phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP).


ensembl_gene_id: TOL2_C07520
symbol: engA
gene_biotype: protein_coding
description:
  EngC: ribosome small subunit-dependent GTPase A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.


ensembl_gene_id: TOL2_C07620
symbol: arsC
gene_biotype: protein_coding
description:
  ArsC: predicted arsenate reductase (glutaredoxin); Belongs to the low molecular weight phosphotyrosine protein phosphatase family.


ensembl_gene_id: TOL2_C07770
symbol: wecA
gene_biotype: protein_coding
description:
  WecA: putative undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase; Signal peptide.


ensembl_gene_id: TOL2_C07820
symbol: CCK78950.1
gene_biotype: protein_coding
description:
  Putative prevent-host-death family protein; Antitoxin component of a type II toxin-antitoxin (TA) system.


ensembl_gene_id: TOL2_C08080
symbol: arnB
gene_biotype: protein_coding
description:
  ArnB: predicted UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase; Belongs to the DegT/DnrJ/EryC1 family.


ensembl_gene_id: TOL2_C08110
symbol: wecB
gene_biotype: protein_coding
description:
  WecB: UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family.


ensembl_gene_id: TOL2_C08530
symbol: moaB
gene_biotype: protein_coding
description:
  MoaB: molybdenum cofactor biosynthesis protein B; May be involved in the biosynthesis of molybdopterin. Belongs to the MoaB/Mog family.


ensembl_gene_id: TOL2_C08540
symbol: pyrR
gene_biotype: protein_coding
description:
  PyrR: bifunctional protein pyrR (pyrimidine operon regulatory protein; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.


ensembl_gene_id: TOL2_C08550
symbol: mobA
gene_biotype: protein_coding
description:
  MobA: putative molbdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family.


ensembl_gene_id: TOL2_C08570
symbol: moaC
gene_biotype: protein_coding
description:
  MoaC: molybdopterin biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.


ensembl_gene_id: TOL2_C08620
symbol: CCK79030.1
gene_biotype: protein_coding
description:
  Predicted ABC-type molybdate/tungstate transporter, periplasmic substrate binding protein\; Signal peptide.


ensembl_gene_id: TOL2_C08670
symbol: hemA
gene_biotype: protein_coding
description:
  HemA: glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).


ensembl_gene_id: TOL2_C08690
symbol: rnc
gene_biotype: protein_coding
description:
  Rnc: ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.


ensembl_gene_id: TOL2_C08860
symbol: dapF
gene_biotype: protein_coding
description:
  DapF: diaminopimelate epimerase (DAP epimerase); Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.


ensembl_gene_id: TOL2_C09070
symbol: metF2
gene_biotype: protein_coding
description:
  MetF2: methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.


ensembl_gene_id: TOL2_C09140
symbol: CCK79082.1
gene_biotype: protein_coding
description:
  Efflux transporter, RND family, MFP subunit precursor; Signal peptide; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: TOL2_C09210
symbol: CCK79089.1
gene_biotype: protein_coding
description:
  ABC transporter, permease protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: TOL2_C09250
symbol: CCK79093.1
gene_biotype: protein_coding
description:
  Predicted iron ABC transporter, permease protein; Signal peptide; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: TOL2_C09350
symbol: CCK79102.1
gene_biotype: protein_coding
description:
  Molybdopterin oxidoreductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: TOL2_C09490
symbol: fecCD
gene_biotype: protein_coding
description:
  FecCD: ABC-type iron(III) transporter, permease protein; Signal anchor; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: TOL2_C09540
symbol: CCK79120.1
gene_biotype: protein_coding
description:
  Predicted iron ABC transporter, permease protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: TOL2_C09640
symbol: CCK79129.1
gene_biotype: protein_coding
description:
  CRISPR-associated protein, Cas4 family; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Belongs to the CRISPR-associated exonuclease Cas4 family.


ensembl_gene_id: TOL2_C09650
symbol: cas1-2
gene_biotype: protein_coding
description:
  CRISPR-associated protein, Cas1 family; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.


ensembl_gene_id: TOL2_C09660
symbol: cas2-2
gene_biotype: protein_coding
description:
  CRISPR-associated protein, Cas2 family; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.


ensembl_gene_id: TOL2_C09730
symbol: lon2
gene_biotype: protein_coding
description:
  Lon2: peptidase S16, ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.


ensembl_gene_id: TOL2_C09900
symbol: purD
gene_biotype: protein_coding
description:
  PurD: phosphoribosylamine--glycine ligase (glycinamide ribonucleotide synthetase); Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR); Belongs to the GARS family.


ensembl_gene_id: TOL2_C09910
symbol: ddl
gene_biotype: protein_coding
description:
  Ddl: D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.


ensembl_gene_id: TOL2_C09950
symbol: fusA
gene_biotype: protein_coding
description:
  FusA: elongation factor G (EF-G); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2  [...]


ensembl_gene_id: TOL2_C10040
symbol: purF
gene_biotype: protein_coding
description:
  PurF: amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.


ensembl_gene_id: TOL2_C10160
symbol: pabC
gene_biotype: protein_coding
description:
  PabC: aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family.


ensembl_gene_id: TOL2_C10170
symbol: rnfB
gene_biotype: protein_coding
description:
  RnfB: predicted electron transport protein RnfB; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.


ensembl_gene_id: TOL2_C10180
symbol: rnfA
gene_biotype: protein_coding
description:
  RnfA: electron transport complex protein RnfA; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.


ensembl_gene_id: TOL2_C10190
symbol: rnfE
gene_biotype: protein_coding
description:
  RnfE: electron transport complex protein RnfE; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.


ensembl_gene_id: TOL2_C10210
symbol: rnfD
gene_biotype: protein_coding
description:
  RnfD: electron transport complex protien RnfD; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the NqrB/RnfD family.


ensembl_gene_id: TOL2_C10280
symbol: trmL
gene_biotype: protein_coding
description:
  Uncharacterized tRNA/rRNA methyltransferase; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.


ensembl_gene_id: TOL2_C10370
symbol: mip
gene_biotype: protein_coding
description:
  Peptidyl-prolyl cis-trans isomerase; Mip: outer membrane protein MIP (macrophage infectivity potentiator) (peptidyl-proly cis-trans isomerase, FKBP-type).


ensembl_gene_id: TOL2_C10460
symbol: CCK79211.1
gene_biotype: protein_coding
description:
  Periplasmic solute-binding protein; Signal peptide; Belongs to the bacterial solute-binding protein 9 family.


ensembl_gene_id: TOL2_C10500
symbol: gsp
gene_biotype: protein_coding
description:
  Gsp: 4?-phosphopantetheinyl transferase (gramicidin synthetase-activating enzyme); Belongs to the P-Pant transferase superfamily.


ensembl_gene_id: TOL2_C10540
symbol: ham
gene_biotype: protein_coding
description:
  Ham: nucleoside-triphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.


ensembl_gene_id: TOL2_C10630
symbol: dctP5
gene_biotype: protein_coding
description:
  DctP5: TRAP dicarboxylate transporter periplasmic binding protein; Part of the tripartite ATP-independent periplasmic (TRAP) transport system.


ensembl_gene_id: TOL2_C10670
symbol: rpoE
gene_biotype: protein_coding
description:
  RpoE: RNA polymerase sigma-E factor (sigma24); Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: TOL2_C10690
symbol: moaA
gene_biotype: protein_coding
description:
  MoaA: molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.


ensembl_gene_id: TOL2_C10710
symbol: hemC
gene_biotype: protein_coding
description:
  HemC: porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.


ensembl_gene_id: TOL2_C10770
symbol: gmhA
gene_biotype: protein_coding
description:
  GmhA: phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.


ensembl_gene_id: TOL2_C10790
symbol: selA
gene_biotype: protein_coding
description:
  SelA: L-seryl-tRNA(Sec) selenium transferase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.


ensembl_gene_id: TOL2_C10800
symbol: cheD
gene_biotype: protein_coding
description:
  CheD: predicted chemoreceptor glutamine deaminase; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.


ensembl_gene_id: TOL2_C10820
symbol: CCK79247.1
gene_biotype: protein_coding
description:
  RND efflux system, membrane fusion protein (MFP); Signal peptide; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: TOL2_C10830
symbol: mdtB
gene_biotype: protein_coding
description:
  MdtB: multidrug resistance protein, AcrB/AcrD/AcrF family; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: TOL2_C10850
symbol: pyrF
gene_biotype: protein_coding
description:
  PyrF: orotidine 5\'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.


ensembl_gene_id: TOL2_C10880
symbol: nnrD
gene_biotype: protein_coding
description:
  YjeF: uncharacterized predicted carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.  Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase  [...]


ensembl_gene_id: TOL2_C10960
symbol: mdtC
gene_biotype: protein_coding
description:
  MdtC: multidrug resistande protein, AcrB/AcrD/AcrF family; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: TOL2_C10970
symbol: mdtE
gene_biotype: protein_coding
description:
  MdtE: multidurg resistance protein, membrane fusion protein; Signal peptide; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: TOL2_C10980
symbol: ispF
gene_biotype: protein_coding
description:
  IspF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (MECPS); Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).


ensembl_gene_id: TOL2_C11020
symbol: ade
gene_biotype: protein_coding
description:
  Ade: adenine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.


ensembl_gene_id: TOL2_C11050
symbol: uvrB
gene_biotype: protein_coding
description:
  UvrB: UvrABC system protein B (Excinuclease ABC subunit B); The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is fou [...]


ensembl_gene_id: TOL2_C11060
symbol: uvrC
gene_biotype: protein_coding
description:
  UvrC: UvrABC system protein C (Excinuclease ABC subunit C); The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.


ensembl_gene_id: TOL2_C11190
symbol: pdxJ
gene_biotype: protein_coding
description:
  PdxJ: pyridoxine 5?-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.


ensembl_gene_id: TOL2_C11200
symbol: ybeY
gene_biotype: protein_coding
description:
  Conserved uncharacterized protein, UPF0054; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.


ensembl_gene_id: TOL2_C11440
symbol: aspS
gene_biotype: protein_coding
description:
  AspS: aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.


ensembl_gene_id: TOL2_C11460
symbol: gatB
gene_biotype: protein_coding
description:
  GatB: glutamyl-tRNA(Gln) amidotransferase, subunit B; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily.


ensembl_gene_id: TOL2_C11480
symbol: trmH
gene_biotype: protein_coding
description:
  TrmH: RNA methyltransferase, group 1; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.


ensembl_gene_id: TOL2_C11490
symbol: dtd
gene_biotype: protein_coding
description:
  Dtd: D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family.


ensembl_gene_id: TOL2_C11660
symbol: fdhH
gene_biotype: protein_coding
description:
  FdhH: formate dehydrogenase H; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: TOL2_C11750
symbol: mor
gene_biotype: protein_coding
description:
  Mor: molybdopterin oxidoreductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: TOL2_C11760
symbol: epd
gene_biotype: protein_coding
description:
  Epd: D-erythrose-4-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.


ensembl_gene_id: TOL2_C11850
symbol: folD
gene_biotype: protein_coding
description:
  FolD: bifunctional protein folD [includes: methylenetetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.


ensembl_gene_id: TOL2_C11930
symbol: ispE
gene_biotype: protein_coding
description:
  IspE: 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase (CMK); Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.


ensembl_gene_id: TOL2_C11940
symbol: prs
gene_biotype: protein_coding
description:
  Prs: ribose-phosphate pyrophosphokinase (RPPK); Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.


ensembl_gene_id: TOL2_C11950
symbol: rplY
gene_biotype: protein_coding
description:
  RplY: 50S ribosomal protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.


ensembl_gene_id: TOL2_C11960
symbol: pth
gene_biotype: protein_coding
description:
  Pth: peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.


ensembl_gene_id: TOL2_C11980
symbol: rluD
gene_biotype: protein_coding
description:
  RluD: ribosomal large subunit pseudouridine synthase D (rRNA-uridine isomerase D); Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.


ensembl_gene_id: TOL2_C11990
symbol: morA
gene_biotype: protein_coding
description:
  MorA: molybdopterin oxidoreductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: TOL2_C12010
symbol: rnfB-2
gene_biotype: protein_coding
description:
  FAD-dependent oxidoreductase; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.


ensembl_gene_id: TOL2_C12050
symbol: ftsZ
gene_biotype: protein_coding
description:
  FtsZ: cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.


ensembl_gene_id: TOL2_C12060
symbol: ftsA
gene_biotype: protein_coding
description:
  FtsA: cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.


ensembl_gene_id: TOL2_C12100
symbol: murG
gene_biotype: protein_coding
description:
  MurG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.


ensembl_gene_id: TOL2_C12120
symbol: murD
gene_biotype: protein_coding
description:
  MurD: UDP-N-acetylmuramoyl-L-alanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.


ensembl_gene_id: TOL2_C12130
symbol: mraY
gene_biotype: protein_coding
description:
  MraY: phospho-N-acetylmuramoyl-pentapeptide-transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.


ensembl_gene_id: TOL2_C12140
symbol: murEF
gene_biotype: protein_coding
description:
  MurEF: fusion protein; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.


ensembl_gene_id: TOL2_C12170
symbol: mraW
gene_biotype: protein_coding
description:
  MraW: S-adenosyl-L-methionine-dependent methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.


ensembl_gene_id: TOL2_C12270
symbol: birA2
gene_biotype: protein_coding
description:
  BirA2: biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.


ensembl_gene_id: TOL2_C12290
symbol: betT
gene_biotype: protein_coding
description:
  BetT: betaine / carnitine / choline transporter; Belongs to the BCCT transporter (TC 2.A.15) family.


ensembl_gene_id: TOL2_C12450
symbol: waaA
gene_biotype: protein_coding
description:
  WaaA: 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.


ensembl_gene_id: TOL2_C12460
symbol: lpxK
gene_biotype: protein_coding
description:
  LpxK: tetraacyldisaccharide 4?-kinase (lipid A 4?-kinase); Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).


ensembl_gene_id: TOL2_C12550
symbol: kdsB
gene_biotype: protein_coding
description:
  KdsB: 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.


ensembl_gene_id: TOL2_C12610
symbol: hemN
gene_biotype: protein_coding
description:
  HemN: oxygen-independent coproporphyrinogen-III oxidase 1 (coproporphyrinogenase); Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.


ensembl_gene_id: TOL2_C13020
symbol: thiM
gene_biotype: protein_coding
description:
  ThiM: hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family.


ensembl_gene_id: TOL2_C13050
symbol: CCK79468.1
gene_biotype: protein_coding
description:
  Peptidyl-prolyl cis-trans isomerase, cyclophilin-type; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.


ensembl_gene_id: TOL2_C13060
symbol: surE
gene_biotype: protein_coding
description:
  SurE: 5?-nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.


ensembl_gene_id: TOL2_C13250
symbol: metS
gene_biotype: protein_coding
description:
  MetG: methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.


ensembl_gene_id: TOL2_C13300
symbol: ostA
gene_biotype: protein_coding
description:
  OstA: organic solvent tolerance protein; Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane; Belongs to the LptD family.


ensembl_gene_id: TOL2_C13400
symbol: recR
gene_biotype: protein_coding
description:
  RecR: recombination protein R; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.


ensembl_gene_id: TOL2_C13410
symbol: CCK79504.1
gene_biotype: protein_coding
description:
  Conserved uncharacterized protein, UPF0149; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.


ensembl_gene_id: TOL2_C13420
symbol: dnaX
gene_biotype: protein_coding
description:
  DnaX: DNA polymerase III, subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.


ensembl_gene_id: TOL2_C13480
symbol: groS
gene_biotype: protein_coding
description:
  GroS: 10kDa chaperonin GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.


ensembl_gene_id: TOL2_C13490
symbol: groL
gene_biotype: protein_coding
description:
  GroL: 60kDa chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.


ensembl_gene_id: TOL2_C13530
symbol: tolB
gene_biotype: protein_coding
description:
  TolB: tol-pal system, periplasmic component; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: TOL2_C13540
symbol: pal-2
gene_biotype: protein_coding
description:
  Predicted peptidoglycan-associated lipoprotein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: TOL2_C13550
symbol: ybgF
gene_biotype: protein_coding
description:
  YbgF: Tol-Pal system, periplasmic component; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family.


ensembl_gene_id: TOL2_C13560
symbol: ruvC
gene_biotype: protein_coding
description:
  RuvC: crossover junction endodeoxyribonuclease; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.


ensembl_gene_id: TOL2_C13570
symbol: ruvA
gene_biotype: protein_coding
description:
  RuvA: holliday junction ATP-dependent DNA helicase; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.


ensembl_gene_id: TOL2_C13580
symbol: ruvB
gene_biotype: protein_coding
description:
  RuvB: holliday junction ATP-dependent DNA helicase, subunit B; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.


ensembl_gene_id: TOL2_C13610
symbol: rplM
gene_biotype: protein_coding
description:
  RplM: 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.


ensembl_gene_id: TOL2_C13640
symbol: hupA
gene_biotype: protein_coding
description:
  HupA: DNA-binding protein HU 1; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.


ensembl_gene_id: TOL2_C13660
symbol: pilD
gene_biotype: protein_coding
description:
  PilD: type 4 prepilin-like proteins leader peptide-processing enzyme; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.


ensembl_gene_id: TOL2_C13670
symbol: lon3
gene_biotype: protein_coding
description:
  Lon3: ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.


ensembl_gene_id: TOL2_C13690
symbol: psd
gene_biotype: protein_coding
description:
  Psd: phosphatidylserine decarboxylase proenzyme (alpha and beta chain); Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).


ensembl_gene_id: TOL2_C13700
symbol: pssA
gene_biotype: protein_coding
description:
  PssA: CDP-diacylglycerol--serine O-phosphatidyltranserase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: TOL2_C13710
symbol: greA
gene_biotype: protein_coding
description:
  GreA: transcription elongation factor; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.


ensembl_gene_id: TOL2_C13720
symbol: rpoZ
gene_biotype: protein_coding
description:
  RpoZ: DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.


ensembl_gene_id: TOL2_C13900
symbol: gspE2
gene_biotype: protein_coding
description:
  GspE2: general secretion pathway protein E; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.


ensembl_gene_id: TOL2_C14080
symbol: gmd
gene_biotype: protein_coding
description:
  Gmd: GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose.


ensembl_gene_id: TOL2_C14090
symbol: CCK79572.1
gene_biotype: protein_coding
description:
  Putative ABC transporter (type 2), peramease protein, putative function in lipopolysaccharide export.


ensembl_gene_id: TOL2_C14140
symbol: algI
gene_biotype: protein_coding
description:
  AlgI: predicted poly(beta-D-mannuronate) O-acetylase; Belongs to the membrane-bound acyltransferase family.


ensembl_gene_id: TOL2_C14370
symbol: efp
gene_biotype: protein_coding
description:
  Efp: elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.


ensembl_gene_id: TOL2_C14380
symbol: topA
gene_biotype: protein_coding
description:
  TopA: DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DN [...]


ensembl_gene_id: TOL2_C14400
symbol: cpoB
gene_biotype: protein_coding
description:
  Predicted tetratricopeptide domain protein; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family.


ensembl_gene_id: TOL2_C14410
symbol: secF
gene_biotype: protein_coding
description:
  SecF: protein-export membrane protein F; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.


ensembl_gene_id: TOL2_C14420
symbol: secD
gene_biotype: protein_coding
description:
  SecD: protein-export membrane protein D; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.


ensembl_gene_id: TOL2_C14430
symbol: yajC
gene_biotype: protein_coding
description:
  YajC: predicted preprotein translocase, subunit; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.


ensembl_gene_id: TOL2_C14460
symbol: mltF
gene_biotype: protein_coding
description:
  MltF: membrane-bound lytic murein transglycosylase F; Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella. In the N-terminal section; belongs to the bacterial solute- binding protein 3 family.


ensembl_gene_id: TOL2_C14470
symbol: parC
gene_biotype: protein_coding
description:
  ParC: DNA topoisomerase 4, subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.


ensembl_gene_id: TOL2_C14480
symbol: parE
gene_biotype: protein_coding
description:
  ParE: DNA topoisomerase 4, subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily.


ensembl_gene_id: TOL2_C14520
symbol: ptsI
gene_biotype: protein_coding
description:
  PtsI: phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).


ensembl_gene_id: TOL2_C14530
symbol: smpB
gene_biotype: protein_coding
description:
  SmpB: SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switc [...]


ensembl_gene_id: TOL2_C14820
symbol: miaB
gene_biotype: protein_coding
description:
  MiaB: (dimethylallyl)adenosine tRNA methylthiotransferase; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.


ensembl_gene_id: TOL2_C14830
symbol: map
gene_biotype: protein_coding
description:
  Map: methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.


ensembl_gene_id: TOL2_C14840
symbol: plsC
gene_biotype: protein_coding
description:
  PlsC: 1-acyl-sn-glycerol-3-phosphate acyltransferase; Signal anchor; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.


ensembl_gene_id: TOL2_C14890
symbol: rsmB
gene_biotype: protein_coding
description:
  RsmB: ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.


ensembl_gene_id: TOL2_C14900
symbol: fmt
gene_biotype: protein_coding
description:
  Fmt: methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.


ensembl_gene_id: TOL2_C14910
symbol: def
gene_biotype: protein_coding
description:
  Def: peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.


ensembl_gene_id: TOL2_C14920
symbol: ribF
gene_biotype: protein_coding
description:
  RibF: riboflavin biosynthesis protein [Includes: riboflavin kinase (flavokinase); FMN adenylyltransferase (FAD pyrophosphorylase)]; Belongs to the ribF family.


ensembl_gene_id: TOL2_C15290
symbol: ctaC
gene_biotype: protein_coding
description:
  CtaC: predicted cytochrome c oxidase, subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).


ensembl_gene_id: TOL2_C15620
symbol: CCK79725.1
gene_biotype: protein_coding
description:
  Putative molybdopterin oxidoreductase, associated with bss3-genes; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: TOL2_C15660
symbol: fdhD2
gene_biotype: protein_coding
description:
  fdhD2: formate dehydrogenase family accessory protein; Required for formate dehydrogenase (FDH) activity. Belongs to the FdhD family.


ensembl_gene_id: TOL2_C15780
symbol: CCK79741.1
gene_biotype: protein_coding
description:
  Molybdenum cofactor cytidylyltransferase; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.


ensembl_gene_id: TOL2_C15920
symbol: idi
gene_biotype: protein_coding
description:
  Idi: isopentenyl-diphosphate delta-isomerase; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).


ensembl_gene_id: TOL2_C15990
symbol: CCK79761.1
gene_biotype: protein_coding
description:
  Predicted 2,3-dihydroxybenzoate-AMP ligase, associated with genes of phenol catabolism; Signal peptide.


ensembl_gene_id: TOL2_C16030
symbol: ppcY
gene_biotype: protein_coding
description:
  PpcY: predicted subunit of carboxylase involved in anaerobic phenol degradation; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family.


ensembl_gene_id: TOL2_C16120
symbol: gpsA
gene_biotype: protein_coding
description:
  GpsA: glycerol-3-phosphate dehydrogenase; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.


ensembl_gene_id: TOL2_C16140
symbol: waaA2
gene_biotype: protein_coding
description:
  WaaA2: 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.


ensembl_gene_id: TOL2_C16210
symbol: rlmB
gene_biotype: protein_coding
description:
  RlmB: 23S rRNA (guanosine-2\'-O-)-methyltransferase; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.


ensembl_gene_id: TOL2_C16290
symbol: ndk
gene_biotype: protein_coding
description:
  Ndk: nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.


ensembl_gene_id: TOL2_C16300
symbol: coaE
gene_biotype: protein_coding
description:
  CoaE: dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.


ensembl_gene_id: TOL2_C16310
symbol: rho2
gene_biotype: protein_coding
description:
  Rho2: transcription termination factor rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.


ensembl_gene_id: TOL2_C16330
symbol: prfA
gene_biotype: protein_coding
description:
  PrfA: peptide chain release factor 1 (RF-1); Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.


ensembl_gene_id: TOL2_C16340
symbol: hemK
gene_biotype: protein_coding
description:
  HemK: protein methyltransferase; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.


ensembl_gene_id: TOL2_C16360
symbol: tsf
gene_biotype: protein_coding
description:
  Tsf: elongation factor Ts (EF-Ts); Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.


ensembl_gene_id: TOL2_C16370
symbol: pyrH2
gene_biotype: protein_coding
description:
  PyrH2, uridylate kinase (Uridine monophosphate kinase); Catalyzes the reversible phosphorylation of UMP to UDP.


ensembl_gene_id: TOL2_C16380
symbol: frr
gene_biotype: protein_coding
description:
  Frr: ribosome-recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.


ensembl_gene_id: TOL2_C16390
symbol: uppS
gene_biotype: protein_coding
description:
  UppS: undecaprenyl pyrophosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.


ensembl_gene_id: TOL2_C16410
symbol: dxr
gene_biotype: protein_coding
description:
  Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 1.1.1.267; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family.


ensembl_gene_id: TOL2_C16430
symbol: purL
gene_biotype: protein_coding
description:
  PurL: phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to a [...]


ensembl_gene_id: TOL2_C16460
symbol: rnj
gene_biotype: protein_coding
description:
  Predicted ribonuclease J 1; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.


ensembl_gene_id: TOL2_C16490
symbol: CCK79811.1
gene_biotype: protein_coding
description:
  Conserved uncharacterized protein, DUF558; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.


ensembl_gene_id: TOL2_C16510
symbol: valS
gene_biotype: protein_coding
description:
  ValS: valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.


ensembl_gene_id: TOL2_C16540
symbol: lepA
gene_biotype: protein_coding
description:
  LepA: GTP-binding protein, related to EF-G and EF-Tu; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.


ensembl_gene_id: TOL2_C16600
symbol: rpoE2
gene_biotype: protein_coding
description:
  RpoE2: RNA polymerase sigma-E factor (sigma24); Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: TOL2_C16630
symbol: leuA2
gene_biotype: protein_coding
description:
  LeuA2: 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.


ensembl_gene_id: TOL2_C16640
symbol: leuA3
gene_biotype: protein_coding
description:
  LeuA3, 2-isopropylmalate synthase 2.3.3.13; Belongs to the alpha-IPM synthase/homocitrate synthase family.


ensembl_gene_id: TOL2_C16720
symbol: cmoA
gene_biotype: protein_coding
description:
  tRNA (cmo5U34)-methyltransferase; Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).


ensembl_gene_id: TOL2_C16730
symbol: cmoB
gene_biotype: protein_coding
description:
  tRNA (mo5U34)-methyltransferase; Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L- methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5- carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.


ensembl_gene_id: TOL2_C17090
symbol: recD
gene_biotype: protein_coding
description:
  RecD: DNA helicase, RecD/TraA type; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily.


ensembl_gene_id: TOL2_C17230
symbol: CCK79884.1
gene_biotype: protein_coding
description:
  RbsV: anti-sigma-B factor antagonist; Signal peptide; Belongs to the anti-sigma-factor antagonist family.


ensembl_gene_id: TOL2_C17580
symbol: iorA2
gene_biotype: protein_coding
description:
  IorA2: indolepyruvate oxidoreductase subunit A; Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.


ensembl_gene_id: TOL2_C17730
symbol: mtnP
gene_biotype: protein_coding
description:
  MtnP: S-methyl-5\'-thioadenosine phosphorylase (5\'-methylthioadenosine phosphorylase); Purine nucleoside phosphorylase involved in purine salvage.


ensembl_gene_id: TOL2_C17740
symbol: apt
gene_biotype: protein_coding
description:
  Apt: adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.


ensembl_gene_id: TOL2_C17810
symbol: metF3
gene_biotype: protein_coding
description:
  MetF3: 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.


ensembl_gene_id: TOL2_C17820
symbol: CCK79943.1
gene_biotype: protein_coding
description:
  Predicted cation efflux protein; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.


ensembl_gene_id: TOL2_C17960
symbol: cheD-2
gene_biotype: protein_coding
description:
  CheD: predicted chemoreceptor glutamine deamidase; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.


ensembl_gene_id: TOL2_C18000
symbol: cheB-2
gene_biotype: protein_coding
description:
  CheB2: chemotaxis response regulator protein-glutamate methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.


ensembl_gene_id: TOL2_C18030
symbol: selO
gene_biotype: protein_coding
description:
  Conserved uncharacterized protein, UPF0061; Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation). Belongs to the SELO family.


ensembl_gene_id: TOL2_C18100
symbol: adk
gene_biotype: protein_coding
description:
  Adk: adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.


ensembl_gene_id: TOL2_C18130
symbol: eno
gene_biotype: protein_coding
description:
  Eno: enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.


ensembl_gene_id: TOL2_C18150
symbol: pyrG
gene_biotype: protein_coding
description:
  PyrG: CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.


ensembl_gene_id: TOL2_C18190
symbol: pat
gene_biotype: protein_coding
description:
  Pat: predicted phenylalanine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: TOL2_C18300
symbol: CCK79991.1
gene_biotype: protein_coding
description:
  Cytidyltransferase-related protein; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.


ensembl_gene_id: TOL2_C18320
symbol: selD
gene_biotype: protein_coding
description:
  SelD: selenide, water dikinase (selenophosphate synthetase); Synthesizes selenophosphate from selenide and ATP.


ensembl_gene_id: TOL2_C18350
symbol: atpB
gene_biotype: protein_coding
description:
  AtpB: ATP synthase, subunit A (F-ATPase subunit 6) (ATP synthase F0 sector subunit a); Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.


ensembl_gene_id: TOL2_C18360
symbol: atpE
gene_biotype: protein_coding
description:
  AtpE: ATP synthase, subunit C (ATP synthase F(0) sector subunit c) (F-type ATPase subunit c); F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.


ensembl_gene_id: TOL2_C18400
symbol: padJ
gene_biotype: protein_coding
description:
  PadJ: phenylacetate-CoA ligase; Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).


ensembl_gene_id: TOL2_C18410
symbol: crt2
gene_biotype: protein_coding
description:
  Crt2: 3-hydroxybutyryl-CoA dehydrogenase (crotonase); Belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: TOL2_C18430
symbol: mutS
gene_biotype: protein_coding
description:
  MutS: DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.


ensembl_gene_id: TOL2_C18470
symbol: hutU
gene_biotype: protein_coding
description:
  HutU: urocanate hydratase (urocanase); Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate.


ensembl_gene_id: TOL2_C18500
symbol: dgt
gene_biotype: protein_coding
description:
  Dgt: deoxyguanosinetriphosphate triphosphohydrolase-like protein; Belongs to the dGTPase family. Type 2 subfamily.


ensembl_gene_id: TOL2_C18510
symbol: CCK80012.1
gene_biotype: protein_coding
description:
  Conserved uncharacterized protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.


ensembl_gene_id: TOL2_C18540
symbol: rpoH
gene_biotype: protein_coding
description:
  RpoH: RNA polymerase sigma32 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.


ensembl_gene_id: TOL2_C18750
symbol: prfC
gene_biotype: protein_coding
description:
  PrfC: peptide chain release factor 3 (RF-3); Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.


ensembl_gene_id: TOL2_C18760
symbol: serC
gene_biotype: protein_coding
description:
  SerC: phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.


ensembl_gene_id: TOL2_C18770
symbol: serA1
gene_biotype: protein_coding
description:
  SerA: D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: TOL2_C18790
symbol: CCK80040.1
gene_biotype: protein_coding
description:
  Conserved uncharacterized protein, DUF558, putative methyltransferase; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.


ensembl_gene_id: TOL2_C18920
symbol: CCK80053.1
gene_biotype: protein_coding
description:
  Predicted, olybdopterin oxidoreductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: TOL2_C18980
symbol: cheB-3
gene_biotype: protein_coding
description:
  Two component system response regulator modulated glutamate methylesterase (CheB-like); Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.


ensembl_gene_id: TOL2_C19040
symbol: proA
gene_biotype: protein_coding
description:
  ProA: gamma-glutamyl phosphate reductase (glutamate-5-semialdehyde dehydrogenase); Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.


ensembl_gene_id: TOL2_C19050
symbol: proB
gene_biotype: protein_coding
description:
  ProB: glutamate 5-kinase (gamma-glutamyl kinase); Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.


ensembl_gene_id: TOL2_C19140
symbol: speH
gene_biotype: protein_coding
description:
  SpeH: S-adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.


ensembl_gene_id: TOL2_C19150
symbol: speE2
gene_biotype: protein_coding
description:
  SpeE2: spermidine synthase (putrescine aminopropyltransferase); Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.


ensembl_gene_id: TOL2_C19650
symbol: mrdB
gene_biotype: protein_coding
description:
  MrdB: rod shape-determining protein rodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.


ensembl_gene_id: TOL2_C19660
symbol: atpF
gene_biotype: protein_coding
description:
  ATP synthase subunit b; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family.


ensembl_gene_id: TOL2_C19670
symbol: atpF2
gene_biotype: protein_coding
description:
  AtpF2: ATP synthase, subunit B (ATP synthase F(0) sector subunit b) (F-type ATPase subunit b); Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family.


ensembl_gene_id: TOL2_C19680
symbol: atpH
gene_biotype: protein_coding
description:
  ATP synthase subunit delta; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family.


ensembl_gene_id: TOL2_C19690
symbol: atpA
gene_biotype: protein_coding
description:
  AtpA: ATP synthase subunit alpha (F-ATPase subunit alpha) (ATP synthase F1 sector subunit alpha); Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family.


ensembl_gene_id: TOL2_C19700
symbol: atpG
gene_biotype: protein_coding
description:
  AtpG: ATP synthase gamma chain (ATP synthase F1 sector gamma subunit) (F-ATPase gamma subunit); Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.


ensembl_gene_id: TOL2_C19710
symbol: atpD
gene_biotype: protein_coding
description:
  AtpD: ATP synthase, subunit beta (F-ATPase subunit beta) (ATP synthase F1 sector subunit beta); Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family.


ensembl_gene_id: TOL2_C19720
symbol: atpC
gene_biotype: protein_coding
description:
  ATP synthase epsilon chain; Produces ATP from ADP in the presence of a proton gradient across the membrane.


ensembl_gene_id: TOL2_C19760
symbol: rny
gene_biotype: protein_coding
description:
  2\',3\'-cyclic-nucleotide 2\'-phosphodiesterase; Endoribonuclease that initiates mRNA decay. Belongs to the RNase Y family.


ensembl_gene_id: TOL2_C19770
symbol: tyrS
gene_biotype: protein_coding
description:
  TyrS: tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.


ensembl_gene_id: TOL2_C19780
symbol: xseA
gene_biotype: protein_coding
description:
  XseA: exodeoxyribonuclease VII, large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family.


ensembl_gene_id: TOL2_C19790
symbol: xseB
gene_biotype: protein_coding
description:
  XseB: exodeoxyribonuclease VII, small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.


ensembl_gene_id: TOL2_C19800
symbol: ispA
gene_biotype: protein_coding
description:
  IspA: geranyltranstransferase (Farnesyl-diphosphate synthase); Belongs to the FPP/GGPP synthase family.


ensembl_gene_id: TOL2_C19810
symbol: dxs
gene_biotype: protein_coding
description:
  Dxs: 1-deoxy-D-xylulose-5-phosphate synthase 1; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.


ensembl_gene_id: TOL2_C19880
symbol: purC
gene_biotype: protein_coding
description:
  PurC: phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family.


ensembl_gene_id: TOL2_C19910
symbol: aroC
gene_biotype: protein_coding
description:
  AroC: chorismate synthase (5-enolpyruvylshikimate-3-phosphate phospholyase); Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.


ensembl_gene_id: TOL2_C19920
symbol: aroK
gene_biotype: protein_coding
description:
  AroK: shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.


ensembl_gene_id: TOL2_C19930
symbol: aroA
gene_biotype: protein_coding
description:
  AroA: 3-phosphoshikimate 1-carboxyvinyltransferase 1; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.


ensembl_gene_id: TOL2_C19940
symbol: aroE
gene_biotype: protein_coding
description:
  AroE: shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).


ensembl_gene_id: TOL2_C19970
symbol: lpxB
gene_biotype: protein_coding
description:
  LpxB: lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: TOL2_C19990
symbol: lpxA
gene_biotype: protein_coding
description:
  LpxA: acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: TOL2_C20000
symbol: lpxD
gene_biotype: protein_coding
description:
  LpxD: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily.


ensembl_gene_id: TOL2_C20030
symbol: lolD
gene_biotype: protein_coding
description:
  LolD: lipoprotein-releasing system ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.


ensembl_gene_id: TOL2_C20080
symbol: CCK80169.1
gene_biotype: protein_coding
description:
  Predicted polyA polymerase family protein; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.


ensembl_gene_id: TOL2_C20090
symbol: trpS
gene_biotype: protein_coding
description:
  TrpS: tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: TOL2_C20100
symbol: rluF
gene_biotype: protein_coding
description:
  RluF: ribosomal large subunit pseudouridine synthase F; Belongs to the pseudouridine synthase RsuA family.


ensembl_gene_id: TOL2_C20110
symbol: argJ
gene_biotype: protein_coding
description:
  ArgJ: arginine biosynthesis bifunctional protein [Includes: glutamate N-acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.


ensembl_gene_id: TOL2_C20250
symbol: CCK80186.1
gene_biotype: protein_coding
description:
  Conserved uncharacterized integral membrane protein, DUF165; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.


ensembl_gene_id: TOL2_C20480
symbol: CCK80209.1
gene_biotype: protein_coding
description:
  Predicted antitoxin of toxin-antitoxin stability system; Antitoxin component of a type II toxin-antitoxin (TA) system.


ensembl_gene_id: TOL2_C20950
symbol: gcvH
gene_biotype: protein_coding
description:
  GcvH: glycine cleavage system, H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.


ensembl_gene_id: TOL2_C20960
symbol: gcvPA
gene_biotype: protein_coding
description:
  GcvPA: glycine dehydrogenase (decarboxylating), glycine cleavage system P protein, subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.


ensembl_gene_id: TOL2_C20980
symbol: lipB
gene_biotype: protein_coding
description:
  LipB: lipoyl(octanoyl) transferas (lipoate-protein ligase B); Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.


ensembl_gene_id: TOL2_C20990
symbol: lipA
gene_biotype: protein_coding
description:
  LipA: lipoyl synthase (lipoate synthase); Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.


ensembl_gene_id: TOL2_C21030
symbol: lgt
gene_biotype: protein_coding
description:
  Lgt: prolipoprotein diacylglycyeryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.


ensembl_gene_id: TOL2_C21040
symbol: lspA
gene_biotype: protein_coding
description:
  LspA: signal peptidase II (lipoprotein signal peptidase); This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.


ensembl_gene_id: TOL2_C21050
symbol: ileS
gene_biotype: protein_coding
description:
  IleS: isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.


ensembl_gene_id: TOL2_C21060
symbol: rsmG
gene_biotype: protein_coding
description:
  RsmG: ribosomal RNA small subunit methyltransferase G; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.


ensembl_gene_id: TOL2_C21070
symbol: fusA3
gene_biotype: protein_coding
description:
  FusA3: elongation factor G (EF-G); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 [...]


ensembl_gene_id: TOL2_C21120
symbol: mnmA
gene_biotype: protein_coding
description:
  MnmA: tRNA-specific 2-thiouridylase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.


ensembl_gene_id: TOL2_C21180
symbol: guaB
gene_biotype: protein_coding
description:
  GuaB: inosine-5\'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.


ensembl_gene_id: TOL2_C21220
symbol: manC
gene_biotype: protein_coding
description:
  ManC: mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family.


ensembl_gene_id: TOL2_C21290
symbol: coaBC
gene_biotype: protein_coding
description:
  Coenzyme A biosynthesis bifunctional protein CoaBC; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.


ensembl_gene_id: TOL2_C21360
symbol: ubiA
gene_biotype: protein_coding
description:
  UbiA: predicted 4-hydroxybenzoate octaprenyltransferase; Belongs to the UbiA prenyltransferase family.


ensembl_gene_id: TOL2_C21520
symbol: CCK80313.1
gene_biotype: protein_coding
description:
  Predicted D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: TOL2_C21630
symbol: glmM
gene_biotype: protein_coding
description:
  GlmM: phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.


ensembl_gene_id: TOL2_C21660
symbol: fabH
gene_biotype: protein_coding
description:
  FabH: 3-oxoacyl-[acyl-carrier-protein] synthase 3; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.


ensembl_gene_id: TOL2_C21710
symbol: livH3
gene_biotype: protein_coding
description:
  LivH3: high-affinity branched-chain amino acid transport system, permease protein; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: TOL2_C21720
symbol: livM3
gene_biotype: protein_coding
description:
  LivM3: high-affinity branched-chain amino acid transport system, permease protein; Signal peptide; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: TOL2_C21850
symbol: CCK80346.1
gene_biotype: protein_coding
description:
  Predicted cation/multidrug efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: TOL2_C21860
symbol: CCK80347.1
gene_biotype: protein_coding
description:
  Efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: TOL2_C21910
symbol: pyrC
gene_biotype: protein_coding
description:
  PyrC: dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.


ensembl_gene_id: TOL2_C21920
symbol: pyrB
gene_biotype: protein_coding
description:
  PyrB: aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.


ensembl_gene_id: TOL2_C22010
symbol: rpoN
gene_biotype: protein_coding
description:
  RpoN: RNA polymerase sigma54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.


ensembl_gene_id: TOL2_C22060
symbol: gap
gene_biotype: protein_coding
description:
  Gap: glyceraldehyde-3-phosphate dehydrogenase (phosphorylating); Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.


ensembl_gene_id: TOL2_C22070
symbol: tpiA
gene_biotype: protein_coding
description:
  TpiA: triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.


ensembl_gene_id: TOL2_C22080
symbol: secG
gene_biotype: protein_coding
description:
  SecG: preprotein translocase, subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.


ensembl_gene_id: TOL2_C22160
symbol: ftsY
gene_biotype: protein_coding
description:
  FtsY: signal recognition particle-docking protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.


ensembl_gene_id: TOL2_C22180
symbol: ligA
gene_biotype: protein_coding
description:
  LigA: DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.


ensembl_gene_id: TOL2_C22290
symbol: dinB
gene_biotype: protein_coding
description:
  DinB: DNA-directed DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. Belongs to the DNA polymerase type-Y family.


ensembl_gene_id: TOL2_C22450
symbol: rumA
gene_biotype: protein_coding
description:
  RumA: predicted 23S rRNA mehtyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.


ensembl_gene_id: TOL2_C22500
symbol: trpE
gene_biotype: protein_coding
description:
  TrpE: anthranilate synthase, component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high c [...]


ensembl_gene_id: TOL2_C22520
symbol: trpD2
gene_biotype: protein_coding
description:
  TrpD2: antrhranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).


ensembl_gene_id: TOL2_C22600
symbol: ftsB
gene_biotype: protein_coding
description:
  FtsB: putative septum formation initiator protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.


ensembl_gene_id: TOL2_C22610
symbol: mviN
gene_biotype: protein_coding
description:
  MviN: integral membrane protein; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.


ensembl_gene_id: TOL2_C22830
symbol: rpsR
gene_biotype: protein_coding
description:
  RpsR: 30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.


ensembl_gene_id: TOL2_C22860
symbol: dnaB
gene_biotype: protein_coding
description:
  DnaB: replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily.


ensembl_gene_id: TOL2_C22870
symbol: hflX
gene_biotype: protein_coding
description:
  HflX: GTP-binding protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.


ensembl_gene_id: TOL2_C22890
symbol: dnaA
gene_biotype: protein_coding
description:
  DnaA: chromosomal replication initiator protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.


ensembl_gene_id: TOL2_C22910
symbol: pdxA
gene_biotype: protein_coding
description:
  PdxA: 4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).


ensembl_gene_id: TOL2_C22920
symbol: uvrA
gene_biotype: protein_coding
description:
  UvrA: UvrABC system, protein A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.


ensembl_gene_id: TOL2_C22960
symbol: wtpC
gene_biotype: protein_coding
description:
  wtpC: molybdate/tungstade transport system, ATP-binding protein; Belongs to the ABC transporter superfamily.


ensembl_gene_id: TOL2_C23390
symbol: capL
gene_biotype: protein_coding
description:
  CapL: biosynthesis protein of type I capsular polysaccharide, nucleotide sugar dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.


ensembl_gene_id: TOL2_C23450
symbol: mfd
gene_biotype: protein_coding
description:
  Mfd: transcription-repair-coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.


ensembl_gene_id: TOL2_C23520
symbol: ispD
gene_biotype: protein_coding
description:
  IspD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).


ensembl_gene_id: TOL2_C23560
symbol: rpoD
gene_biotype: protein_coding
description:
  RpoD: RNA polymerase sigma70 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.


ensembl_gene_id: TOL2_C23570
symbol: dnaG2
gene_biotype: protein_coding
description:
  DnaG2: DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.


ensembl_gene_id: TOL2_C23740
symbol: trkH
gene_biotype: protein_coding
description:
  TrkH: Trk system integral membrane K(+)-translocating protein; Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA; Belongs to the TrkH potassium transport family.


ensembl_gene_id: TOL2_C24100
symbol: truA2
gene_biotype: protein_coding
description:
  TruA2: tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.


ensembl_gene_id: TOL2_C24150
symbol: pfk2
gene_biotype: protein_coding
description:
  Pfk2: phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily.


ensembl_gene_id: TOL2_C24170
symbol: miaA
gene_biotype: protein_coding
description:
  MiaA: tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.


ensembl_gene_id: TOL2_C24300
symbol: murA
gene_biotype: protein_coding
description:
  MurA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.


ensembl_gene_id: TOL2_C24420
symbol: maf
gene_biotype: protein_coding
description:
  Maf: putative inhibitor of septum formation; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.


ensembl_gene_id: TOL2_C24430
symbol: CCK80604.1
gene_biotype: protein_coding
description:
  Alanine racemanse; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.


ensembl_gene_id: TOL2_C24440
symbol: queH
gene_biotype: protein_coding
description:
  Conserved uncharacterized protein, DUF208; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).


ensembl_gene_id: TOL2_C24510
symbol: cheR2
gene_biotype: protein_coding
description:
  CheR2: chemotaxis protein methyltransferase; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.


ensembl_gene_id: TOL2_C24520
symbol: talC
gene_biotype: protein_coding
description:
  TalC: transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.


ensembl_gene_id: TOL2_C24560
symbol: argF
gene_biotype: protein_coding
description:
  ArgF: ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.


ensembl_gene_id: TOL2_C24570
symbol: argD
gene_biotype: protein_coding
description:
  ArgD: acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.


ensembl_gene_id: TOL2_C24580
symbol: argB
gene_biotype: protein_coding
description:
  ArgB: acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.


ensembl_gene_id: TOL2_C24590
symbol: hslU
gene_biotype: protein_coding
description:
  HslU: ATP-dependent hsl protease, ATP-binding subunit; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.


ensembl_gene_id: TOL2_C24600
symbol: hslV
gene_biotype: protein_coding
description:
  HslV: ATP-dependent protease; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.


ensembl_gene_id: TOL2_C24610
symbol: xerC2
gene_biotype: protein_coding
description:
  XerC2: tyrosine recombinase, subunit C; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.


ensembl_gene_id: TOL2_C24740
symbol: corA
gene_biotype: protein_coding
description:
  CorA: magnesium transport protein; Mediates influx of magnesium ions. Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.


ensembl_gene_id: TOL2_C24890
symbol: CCK80650.1
gene_biotype: protein_coding
description:
  Putative multi-domain beta-ketoacyl polyketide synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: TOL2_C25000
symbol: hldE
gene_biotype: protein_coding
description:
  HldE: bifunctional protein [includes: D-beta-D-heptose 7-phosphate kinase and D-beta-D-heptose 7-phosphotranferase].


ensembl_gene_id: TOL2_C25040
symbol: gcp
gene_biotype: protein_coding
description:
  Gcp: predicted O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.


ensembl_gene_id: TOL2_C25090
symbol: acnA
gene_biotype: protein_coding
description:
  AcnA: aconitate hydratase (aconitase); Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.


ensembl_gene_id: TOL2_C25110
symbol: CCK80672.1
gene_biotype: protein_coding
description:
  Putative flagellin protein; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.


ensembl_gene_id: TOL2_C25700
symbol: metF4
gene_biotype: protein_coding
description:
  MetF4: 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.


ensembl_gene_id: TOL2_C25740
symbol: metF5
gene_biotype: protein_coding
description:
  MetF5: 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.


ensembl_gene_id: TOL2_C26420
symbol: rdgA
gene_biotype: protein_coding
description:
  RsgA: predicted ribosome biogenesis GTPase; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.


ensembl_gene_id: TOL2_C26630
symbol: CCK80822.1
gene_biotype: protein_coding
description:
  CDP-alcohol phosphatidyltransferase; Signal peptide; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: TOL2_C26850
symbol: ubiX
gene_biotype: protein_coding
description:
  UbiX: 3-octaprenyl-4-hydroxybenzoate carboxylyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family.


ensembl_gene_id: TOL2_C27020
symbol: idi2
gene_biotype: protein_coding
description:
  Idi2: isopentenyl-diphosphate delta-isomerase; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).


ensembl_gene_id: TOL2_C27030
symbol: CCK80862.1
gene_biotype: protein_coding
description:
  Putative methyl-accepting chemotaxis sensory transducer modulated with TRAP transporter solute receptor.


ensembl_gene_id: TOL2_C28140
symbol: ddl2
gene_biotype: protein_coding
description:
  Ddl2: predicted D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.


ensembl_gene_id: TOL2_C28240
symbol: iorA3
gene_biotype: protein_coding
description:
  IorA3: indolepyruvate oxidoreductase subunit A; Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.


ensembl_gene_id: TOL2_C28250
symbol: mdh
gene_biotype: protein_coding
description:
  Mdh: malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.


ensembl_gene_id: TOL2_C28280
symbol: hisA
gene_biotype: protein_coding
description:
  HisA: 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; Belongs to the HisA/HisF family.


ensembl_gene_id: TOL2_C28370
symbol: hemE
gene_biotype: protein_coding
description:
  HemE: predicted uroporphyrinogen decarboxylase; Belongs to the uroporphyrinogen decarboxylase family.


ensembl_gene_id: TOL2_C28480
symbol: sucD2
gene_biotype: protein_coding
description:
  SucD2: succinyl-CoA ligase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.


ensembl_gene_id: TOL2_C28490
symbol: asd
gene_biotype: protein_coding
description:
  Asd: aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.


ensembl_gene_id: TOL2_C28670
symbol: nqrF
gene_biotype: protein_coding
description:
  NqrF: Na(+)-translocating NADH-quinone reductase, subunit F; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.


ensembl_gene_id: TOL2_C28680
symbol: nqrE
gene_biotype: protein_coding
description:
  NqrE: Na(+)-translocating NADH-quinone reductase, subunit E; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol; Belongs to the NqrDE/RnfAE family.


ensembl_gene_id: TOL2_C28690
symbol: nqrD
gene_biotype: protein_coding
description:
  NqrD: Na(+)-translocating NADH-quinone reductase, subunit D; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol; Belongs to the NqrDE/RnfAE family.


ensembl_gene_id: TOL2_C28700
symbol: nqrC
gene_biotype: protein_coding
description:
  NqrC: Na(+)-translocating NADH-quinone reductase, subunit C; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.


ensembl_gene_id: TOL2_C28710
symbol: nqrB
gene_biotype: protein_coding
description:
  NqrB: Na(+)-translocating NADH-quinone reductase, subunit B; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.


ensembl_gene_id: TOL2_C28720
symbol: nqrA
gene_biotype: protein_coding
description:
  NqrA: Na(+)-translocating NADH-quinone reductase, subunit A; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.


ensembl_gene_id: TOL2_C28740
symbol: ppiA
gene_biotype: protein_coding
description:
  PpiA: peptidyl-prolyl cis-trans isomerase A; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.


ensembl_gene_id: TOL2_C29060
symbol: suhB
gene_biotype: protein_coding
description:
  SuhB: inositol-1-monophosphatase; Signal peptide; Belongs to the inositol monophosphatase superfamily.


ensembl_gene_id: TOL2_C29080
symbol: rbgA
gene_biotype: protein_coding
description:
  RbgA: ribosome biogenesis GTPase; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.


ensembl_gene_id: TOL2_C29270
symbol: fdhA3
gene_biotype: protein_coding
description:
  FdhA3: formate dehydrogenase, subunit A; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: TOL2_C29300
symbol: fdhE
gene_biotype: protein_coding
description:
  FdhE: predicted formate dehydrogenase accessory protein; Necessary for formate dehydrogenase activity. Belongs to the FdhE family.


ensembl_gene_id: TOL2_C29510
symbol: cas1
gene_biotype: protein_coding
description:
  Cas1: CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.


ensembl_gene_id: TOL2_C29520
symbol: cas2
gene_biotype: protein_coding
description:
  Cas2: CRISPR-associated protein Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.


ensembl_gene_id: TOL2_C29580
symbol: cas4
gene_biotype: protein_coding
description:
  Cas4: CRISPR-associated protein Cas4; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Belongs to the CRISPR-associated exonuclease Cas4 family.


ensembl_gene_id: TOL2_C29720
symbol: alaS
gene_biotype: protein_coding
description:
  AlaS: alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.


ensembl_gene_id: TOL2_C29730
symbol: recA
gene_biotype: protein_coding
description:
  RecA: recombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.


ensembl_gene_id: TOL2_C29740
symbol: pgpA
gene_biotype: protein_coding
description:
  PgpA: phosphatidylglycerophosphatase A; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).


ensembl_gene_id: TOL2_C29790
symbol: fumB2
gene_biotype: protein_coding
description:
  FumB2: fumarate hydratase class I (fumarase); Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.


ensembl_gene_id: TOL2_C29990
symbol: argC
gene_biotype: protein_coding
description:
  ArgC: N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.


ensembl_gene_id: TOL2_C30010
symbol: secA
gene_biotype: protein_coding
description:
  SecA: protein translocase, subunit A; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family.


ensembl_gene_id: TOL2_C30020
symbol: clpS
gene_biotype: protein_coding
description:
  ClpS: ATP-dependent Clp protease adapter protein; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family.


ensembl_gene_id: TOL2_C30040
symbol: aat
gene_biotype: protein_coding
description:
  Aat: leucyl/phenylalanyl-tRNA--protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.


ensembl_gene_id: TOL2_C30160
symbol: CCK81175.1
gene_biotype: protein_coding
description:
  DNA-binding protein, histone family; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.


ensembl_gene_id: TOL2_C30220
symbol: tadA
gene_biotype: protein_coding
description:
  TadA: tRNA-specific adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.


ensembl_gene_id: TOL2_C30230
symbol: purA
gene_biotype: protein_coding
description:
  PurA: adenylosuccinate lyase, subunit A; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.


ensembl_gene_id: TOL2_C31180
symbol: rplU
gene_biotype: protein_coding
description:
  RplU: 50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.


ensembl_gene_id: TOL2_C31200
symbol: obg
gene_biotype: protein_coding
description:
  Obg: GTP-binding protein, involved in ribosome maturation; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.


ensembl_gene_id: TOL2_C31210
symbol: nadD
gene_biotype: protein_coding
description:
  NadD: predicted nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).


ensembl_gene_id: TOL2_C31220
symbol: rsfS
gene_biotype: protein_coding
description:
  Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.


ensembl_gene_id: TOL2_C31230
symbol: gpmI
gene_biotype: protein_coding
description:
  GpmI: phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.


ensembl_gene_id: TOL2_C31430
symbol: hisC
gene_biotype: protein_coding
description:
  HisC: histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.


ensembl_gene_id: TOL2_C31630
symbol: mviN-2
gene_biotype: protein_coding
description:
  MviN2: integral membrane protein; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.


ensembl_gene_id: TOL2_C31740
symbol: CCK81332.1
gene_biotype: protein_coding
description:
  Peptide iron ABC transporter, permease protein; Signal anchor; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: TOL2_C31920
symbol: phnJ
gene_biotype: protein_coding
description:
  PhnJ: phopsphonate metabolism protein, predicted C-P lyase subunit; Catalyzes the breakage of the C-P bond in alpha-D-ribose 1- methylphosphonate 5-phosphate (PRPn) forming alpha-D-ribose. Belongs to the PhnJ family.


ensembl_gene_id: TOL2_C31960
symbol: phnC
gene_biotype: protein_coding
description:
  PhnC: phosphonate transport ATP-binding protein; Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family.


ensembl_gene_id: TOL2_C32090
symbol: pstB2
gene_biotype: protein_coding
description:
  PstB2: phosphate transport system, ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.


ensembl_gene_id: TOL2_C32120
symbol: pstC2
gene_biotype: protein_coding
description:
  PstC2: phosphate transport system, permease protein; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: TOL2_C32190
symbol: leuC
gene_biotype: protein_coding
description:
  LeuC: 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.


ensembl_gene_id: TOL2_C32200
symbol: leuD
gene_biotype: protein_coding
description:
  LeuD: 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily.


ensembl_gene_id: TOL2_C32470
symbol: pstC3
gene_biotype: protein_coding
description:
  PstC3: phosphate transport system, permease protein; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: TOL2_C32490
symbol: pstB3
gene_biotype: protein_coding
description:
  PstB3: phosphate transport system, ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.


ensembl_gene_id: TOL2_C32720
symbol: ahcY
gene_biotype: protein_coding
description:
  AhcY: adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.


ensembl_gene_id: TOL2_C32730
symbol: metK
gene_biotype: protein_coding
description:
  MetK: S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.


ensembl_gene_id: TOL2_C32770
symbol: lon4
gene_biotype: protein_coding
description:
  Lon4: ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.


ensembl_gene_id: TOL2_C32800
symbol: feoB2
gene_biotype: protein_coding
description:
  FeoB2: ferrous iron transport protein B; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.


ensembl_gene_id: TOL2_C32880
symbol: tonB
gene_biotype: protein_coding
description:
  TonB: TonB family protein, associated with ExbBD; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.


ensembl_gene_id: TOL2_C32930
symbol: hemU
gene_biotype: protein_coding
description:
  HmuU: hemin transport system, permease protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: TOL2_C33180
symbol: mdtB2
gene_biotype: protein_coding
description:
  MdtB2: multidrug resistance protein, AcrB/AcrD/AcrF family; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: TOL2_C33190
symbol: mdtA
gene_biotype: protein_coding
description:
  MdtA: predicted multidrug resistance protein A; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: TOL2_C33270
symbol: metF6
gene_biotype: protein_coding
description:
  MetF6: 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.


ensembl_gene_id: TOL2_C33380
symbol: cheD2
gene_biotype: protein_coding
description:
  CheD2: predicted chemoreceptor glutamine deamidase; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.


ensembl_gene_id: TOL2_C33430
symbol: CCK81500.1
gene_biotype: protein_coding
description:
  Two-component system response regulator receiver domain modulated ABC-type transport system, periplasmic component.


ensembl_gene_id: TOL2_C33450
symbol: nth
gene_biotype: protein_coding
description:
  Nth: endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.


ensembl_gene_id: TOL2_C33480
symbol: rlmN
gene_biotype: protein_coding
description:
  RlmN: ribosomal RNA large subunit methyltransferase N; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family.


ensembl_gene_id: TOL2_C33490
symbol: ffh
gene_biotype: protein_coding
description:
  Ffh: signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual com [...]


ensembl_gene_id: TOL2_C33520
symbol: rimM
gene_biotype: protein_coding
description:
  RimM: ribosome maturation factor; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family.


ensembl_gene_id: TOL2_C33530
symbol: trmD
gene_biotype: protein_coding
description:
  TrmD: tRNA (guanine-N(1)-)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.


ensembl_gene_id: TOL2_C33550
symbol: rplS
gene_biotype: protein_coding
description:
  RplS: 50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.


ensembl_gene_id: TOL2_C33580
symbol: rsmI
gene_biotype: protein_coding
description:
  Predicted uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.


ensembl_gene_id: TOL2_C33660
symbol: nusB
gene_biotype: protein_coding
description:
  NusB: transcription antitermination factor B; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.


ensembl_gene_id: TOL2_C33670
symbol: ribH
gene_biotype: protein_coding
description:
  RibH: 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.


ensembl_gene_id: TOL2_C33680
symbol: ribBA
gene_biotype: protein_coding
description:
  RibBA: fusion protein: 3,4-dihydroxy-2-butanone 4-phosphate synthase and GTP cyclohydrolase-2; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.


ensembl_gene_id: TOL2_C33700
symbol: ribD
gene_biotype: protein_coding
description:
  RibD: riboflavin synthesis protein D; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.


ensembl_gene_id: TOL2_C33710
symbol: nrdR
gene_biotype: protein_coding
description:
  NrdR: transcriptional repressor; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.


ensembl_gene_id: TOL2_C33730
symbol: glyA
gene_biotype: protein_coding
description:
  GlyA: serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.


ensembl_gene_id: TOL2_C33780
symbol: gltX
gene_biotype: protein_coding
description:
  GltX: glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.


ensembl_gene_id: TOL2_C33800
symbol: hypA
gene_biotype: protein_coding
description:
  HypA: hydrogenase nickel incorporation protein; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.


ensembl_gene_id: TOL2_C33810
symbol: tgt
gene_biotype: protein_coding
description:
  Tgt: queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to f [...]


ensembl_gene_id: TOL2_C33820
symbol: queA
gene_biotype: protein_coding
description:
  QueA: S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).


ensembl_gene_id: TOL2_C33840
symbol: gatB-2
gene_biotype: protein_coding
description:
  GatB2: glutamyl-tRNA(Gln) amidotransferase, subunit B; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily.


ensembl_gene_id: TOL2_C33890
symbol: mutL
gene_biotype: protein_coding
description:
  MutL: DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.


ensembl_gene_id: TOL2_C33910
symbol: gatA2
gene_biotype: protein_coding
description:
  GatA2: glutamyl-tRNA(Gln) amidotransferase, subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln).


ensembl_gene_id: TOL2_C33920
symbol: gatC
gene_biotype: protein_coding
description:
  GatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, subunit C; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family.


ensembl_gene_id: TOL2_C33980
symbol: CCK81555.1
gene_biotype: protein_coding
description:
  iron(III) dicitrate ABC transporter, permease protein; Signal peptide; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: TOL2_C34190
symbol: cbiK
gene_biotype: protein_coding
description:
  CbiK: sirohydrochlorin cobaltochelatase; Catalyzes the insertion of Co(2+) into sirohydrochlorin. Belongs to the CbiK family.


ensembl_gene_id: TOL2_C34220
symbol: CCK81579.1
gene_biotype: protein_coding
description:
  ABC transporter, permease protein; Signal peptide; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: TOL2_C34290
symbol: CCK81586.1
gene_biotype: protein_coding
description:
  Predicted TonB family protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.


ensembl_gene_id: TOL2_C34310
symbol: cbiK2
gene_biotype: protein_coding
description:
  CbiK2: sirohydrochlorin cobaltochelatase; Catalyzes the insertion of Co(2+) into sirohydrochlorin. Belongs to the CbiK family.


ensembl_gene_id: TOL2_C34450
symbol: xerD3
gene_biotype: protein_coding
description:
  XerD3: tyrosine recombinase; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.


ensembl_gene_id: TOL2_C34500
symbol: cofH
gene_biotype: protein_coding
description:
  CofH: F0 synthase, subunit 2; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.


ensembl_gene_id: TOL2_C34510
symbol: cofH2
gene_biotype: protein_coding
description:
  CofH2: F0 synthase, subunit 2; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).


ensembl_gene_id: TOL2_C34530
symbol: mqnA
gene_biotype: protein_coding
description:
  Putative periplasmic binding protein; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).


ensembl_gene_id: TOL2_C34570
symbol: rpoA
gene_biotype: protein_coding
description:
  RpoA: DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: TOL2_C34580
symbol: rpsD
gene_biotype: protein_coding
description:
  RpsD: 30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.


ensembl_gene_id: TOL2_C34590
symbol: rpsK
gene_biotype: protein_coding
description:
  RpsK: 30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.


ensembl_gene_id: TOL2_C34600
symbol: rpsM
gene_biotype: protein_coding
description:
  RpsM: 30S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family.


ensembl_gene_id: TOL2_C34620
symbol: infA
gene_biotype: protein_coding
description:
  InfA: translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.


ensembl_gene_id: TOL2_C34630
symbol: secY
gene_biotype: protein_coding
description:
  SecY: preprotein translocase, subunit Y; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.


ensembl_gene_id: TOL2_C34640
symbol: rplO
gene_biotype: protein_coding
description:
  RplO: 50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.


ensembl_gene_id: TOL2_C34660
symbol: rpsE
gene_biotype: protein_coding
description:
  RpsE: 30S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.


ensembl_gene_id: TOL2_C34670
symbol: rplR
gene_biotype: protein_coding
description:
  RplR: 50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.


ensembl_gene_id: TOL2_C34680
symbol: rplF
gene_biotype: protein_coding
description:
  RplF: 50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.


ensembl_gene_id: TOL2_C34690
symbol: rpsH
gene_biotype: protein_coding
description:
  RpsH: 30S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.


ensembl_gene_id: TOL2_C34700
symbol: rpsZ
gene_biotype: protein_coding
description:
  RpsZ: 30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.


ensembl_gene_id: TOL2_C34710
symbol: rplE
gene_biotype: protein_coding
description:
  RplE: 50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.


ensembl_gene_id: TOL2_C34720
symbol: rplX
gene_biotype: protein_coding
description:
  RplX: 50S ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.


ensembl_gene_id: TOL2_C34730
symbol: rplN
gene_biotype: protein_coding
description:
  RplN: 50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.


ensembl_gene_id: TOL2_C34740
symbol: rpsQ
gene_biotype: protein_coding
description:
  RpsQ: 30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.


ensembl_gene_id: TOL2_C34760
symbol: rplP
gene_biotype: protein_coding
description:
  RplP: 50S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.


ensembl_gene_id: TOL2_C34770
symbol: rpsC
gene_biotype: protein_coding
description:
  RpsC: 30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.


ensembl_gene_id: TOL2_C34780
symbol: rplV
gene_biotype: protein_coding
description:
  RplV: 50S ribosomal protein S50; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.


ensembl_gene_id: TOL2_C34790
symbol: rpsS
gene_biotype: protein_coding
description:
  RpsS: 30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.


ensembl_gene_id: TOL2_C34800
symbol: rplB
gene_biotype: protein_coding
description:
  RplB: 50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.


ensembl_gene_id: TOL2_C34810
symbol: rplW
gene_biotype: protein_coding
description:
  RplW: 50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.


ensembl_gene_id: TOL2_C34830
symbol: rplC
gene_biotype: protein_coding
description:
  RplC: 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.


ensembl_gene_id: TOL2_C34840
symbol: rpsJ
gene_biotype: protein_coding
description:
  RpsJ: 30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.


ensembl_gene_id: TOL2_C34850
symbol: tuf
gene_biotype: protein_coding
description:
  Tuf: elongation factor Tu (EF-Tu); This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.


ensembl_gene_id: TOL2_C34860
symbol: rpsG
gene_biotype: protein_coding
description:
  RpsG: 30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.


ensembl_gene_id: TOL2_C34870
symbol: rpoC
gene_biotype: protein_coding
description:
  RpoC: DNA-directed RNA polymerase, beta\' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: TOL2_C34880
symbol: rpoB
gene_biotype: protein_coding
description:
  RpoB: DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: TOL2_C34890
symbol: rplL
gene_biotype: protein_coding
description:
  RplL: 50S ribosomal protein L7/12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family.


ensembl_gene_id: TOL2_C34900
symbol: rplJ
gene_biotype: protein_coding
description:
  RplJ: 50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.


ensembl_gene_id: TOL2_C34910
symbol: rplA
gene_biotype: protein_coding
description:
  RplA: 50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.


ensembl_gene_id: TOL2_C34920
symbol: rplK
gene_biotype: protein_coding
description:
  RplK: 50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.


ensembl_gene_id: TOL2_C34930
symbol: nusG-2
gene_biotype: protein_coding
description:
  NusG2: transcription antitermination protein; Participates in transcription elongation, termination and antitermination.


ensembl_gene_id: TOL2_C34940
symbol: secE
gene_biotype: protein_coding
description:
  SecE: predicted preprotein translocase, subunit E; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.


ensembl_gene_id: TOL2_C35050
symbol: gyrA
gene_biotype: protein_coding
description:
  GyrA: DNA gyrase, subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.


ensembl_gene_id: TOL2_C35110
symbol: engA-2
gene_biotype: protein_coding
description:
  GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.


ensembl_gene_id: TOL2_C35150
symbol: CCK81672.1
gene_biotype: protein_coding
description:
  Cytidyltransferase domain modulated carbohydrate/purine kinase; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family.


ensembl_gene_id: TOL2_C35270
symbol: arnB2
gene_biotype: protein_coding
description:
  ArnB2: UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase; Belongs to the DegT/DnrJ/EryC1 family.


ensembl_gene_id: TOL2_C35360
symbol: CCK81693.1
gene_biotype: protein_coding
description:
  Cystathione beta-synthase modulated DegT/DnrJ/EryC1/StrS aminotransferase; Belongs to the DegT/DnrJ/EryC1 family.


ensembl_gene_id: TOL2_C35370
symbol: gmd2
gene_biotype: protein_coding
description:
  Gmd2: GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose.


ensembl_gene_id: TOL2_C35440
symbol: flaB
gene_biotype: protein_coding
description:
  FlaB: predicted flagellin B; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.


ensembl_gene_id: TOL2_C35450
symbol: fliD
gene_biotype: protein_coding
description:
  FliD: predicted flagellar hook-associated protein 2; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.


ensembl_gene_id: TOL2_C35490
symbol: fliW
gene_biotype: protein_coding
description:
  FliW: flagellar assembly factor; Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.


ensembl_gene_id: TOL2_C35500
symbol: csrA
gene_biotype: protein_coding
description:
  CsrA: carbon storage regulator homolog, associated with flagellum genes; A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'- UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.


ensembl_gene_id: TOL2_C35520
symbol: flgK
gene_biotype: protein_coding
description:
  FlgK: putative flagellar hook-associated protein 1; Belongs to the flagella basal body rod proteins family.


ensembl_gene_id: TOL2_C35550
symbol: flgI
gene_biotype: protein_coding
description:
  FlgI: flagellar P-ring protein (basal body P-ring protein); Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.


ensembl_gene_id: TOL2_C35560
symbol: flgH
gene_biotype: protein_coding
description:
  FlgH: flagellar L-ring protein (basal body L-ring protein); Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.


ensembl_gene_id: TOL2_C35660
symbol: fliA
gene_biotype: protein_coding
description:
  FliA: RNA polymerase sigma factor for flagellar operon; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.


ensembl_gene_id: TOL2_C35690
symbol: flhA
gene_biotype: protein_coding
description:
  FlhA: flagellar biosynthesis protein, protein export component; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.


ensembl_gene_id: TOL2_C35700
symbol: flhB
gene_biotype: protein_coding
description:
  FlhB: flagellar biosynthesis protein, protein export component; Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the type III secretion exporter family.


ensembl_gene_id: TOL2_C35710
symbol: fliR
gene_biotype: protein_coding
description:
  FliR: flagellar biosynthesis protein, protein export component; Role in flagellar biosynthesis. Belongs to the FliR/MopE/SpaR family.


ensembl_gene_id: TOL2_C35720
symbol: fliQ
gene_biotype: protein_coding
description:
  FliQ: flagellar biosynthesis protein, protein export component; Role in flagellar biosynthesis. Belongs to the FliQ/MopD/SpaQ family.


ensembl_gene_id: TOL2_C35730
symbol: fliP
gene_biotype: protein_coding
description:
  FliP: flagellar biosynthesis protein, protein export component; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family.


ensembl_gene_id: TOL2_C35770
symbol: fliL
gene_biotype: protein_coding
description:
  FliL: predicted flagellar basal body-associated protein; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.


ensembl_gene_id: TOL2_C35790
symbol: flgD
gene_biotype: protein_coding
description:
  FlgD: predicted flagellar hook capping protein; Required for flagellar hook formation. May act as a scaffolding protein.


ensembl_gene_id: TOL2_C35860
symbol: fliF
gene_biotype: protein_coding
description:
  FliF: flagellar M-ring protein; The M ring may be actively involved in energy transduction. Belongs to the FliF family.


ensembl_gene_id: TOL2_C35890
symbol: flgB
gene_biotype: protein_coding
description:
  FlgB: flagellar basal-body rod protein; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.


ensembl_gene_id: TOL2_C35900
symbol: flbD
gene_biotype: protein_coding
description:
  Two-component system, NtrC family, response regulator AtoC; FlbD: two component system response regulator, sigma54-specific, activator of flagellar gene promotors.


ensembl_gene_id: TOL2_C36060
symbol: dus2
gene_biotype: protein_coding
description:
  Dus2: tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.


ensembl_gene_id: TOL2_C36070
symbol: queF
gene_biotype: protein_coding
description:
  QueF: NADPH-dependent 7-cyano-7-deazaguanine reductase (NADPH-dependent nitrile oxidoreductase); Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.


ensembl_gene_id: TOL2_C36100
symbol: era
gene_biotype: protein_coding
description:
  Era: GTP-binding protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.


ensembl_gene_id: TOL2_C36110
symbol: engB
gene_biotype: protein_coding
description:
  EngB: GTP-binding protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.


ensembl_gene_id: TOL2_C36130
symbol: hisG
gene_biotype: protein_coding
description:
  HisG: ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily.


ensembl_gene_id: TOL2_C36140
symbol: hisI
gene_biotype: protein_coding
description:
  HisI: phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.


ensembl_gene_id: TOL2_C36300
symbol: deaD
gene_biotype: protein_coding
description:
  DeaD: cold-shock DEAD box protein; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.


ensembl_gene_id: TOL2_C36360
symbol: ispH
gene_biotype: protein_coding
description:
  IspH: predicted 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.


ensembl_gene_id: TOL2_C36890
symbol: tmk
gene_biotype: protein_coding
description:
  Tmk: thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.


ensembl_gene_id: TOL2_C37060
symbol: dnaJ
gene_biotype: protein_coding
description:
  DnaJ: chaperone protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ,  [...]


ensembl_gene_id: TOL2_C37070
symbol: ubiE
gene_biotype: protein_coding
description:
  UbiE: ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2).


ensembl_gene_id: TOL2_C37140
symbol: mqnB
gene_biotype: protein_coding
description:
  Predicted 5\'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2).


ensembl_gene_id: TOL2_C37150
symbol: aroQ
gene_biotype: protein_coding
description:
  AroQ: 3-dehydroquinate dehydrogenase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.


ensembl_gene_id: TOL2_C37170
symbol: iorA4
gene_biotype: protein_coding
description:
  IorA4: indolepyruvate oxidoreductase subunit A; Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.


ensembl_gene_id: TOL2_C37200
symbol: hslO
gene_biotype: protein_coding
description:
  HslO: heat shock protein, Hsp 33 family; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress; Belongs to the HSP33 family.


ensembl_gene_id: TOL2_C37300
symbol: hsdR2
gene_biotype: protein_coding
description:
  HsdR2: type I site-specific deoxyribonuclease; Subunit R is required for both nuclease and ATPase activities, but not for modification.


ensembl_gene_id: TOL2_C37480
symbol: gidA
gene_biotype: protein_coding
description:
  GidA: tRNA uridine 5-carboxymethylaminomethyl modification enzyme; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family.


ensembl_gene_id: TOL2_C37500
symbol: hpt
gene_biotype: protein_coding
description:
  Hpt: hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.


ensembl_gene_id: TOL2_C37540
symbol: queE
gene_biotype: protein_coding
description:
  Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.


ensembl_gene_id: TOL2_C37550
symbol: queC
gene_biotype: protein_coding
description:
  QueC: queuosine biosynthesis protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.


ensembl_gene_id: TOL2_C37610
symbol: cca
gene_biotype: protein_coding
description:
  Cca: predicted CCA-adding enzyme (tRNA nucleotidyltransferase); Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.


ensembl_gene_id: TOL2_C37620
symbol: ubiA2
gene_biotype: protein_coding
description:
  UbiA2: predicted 4-hydroxybenzoate octaprenyltransferase; Belongs to the UbiA prenyltransferase family.


ensembl_gene_id: TOL2_C37800
symbol: tpx
gene_biotype: protein_coding
description:
  Tpx: thiol peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily.


ensembl_gene_id: TOL2_C37820
symbol: mntP
gene_biotype: protein_coding
description:
  Conserved uncharacterized membrane protein, UPF0059; Probably functions as a manganese efflux pump. Belongs to the MntP (TC 9.B.29) family.


ensembl_gene_id: TOL2_C37890
symbol: ttgG
gene_biotype: protein_coding
description:
  TtgG: toluene efflux pump periplasmic linker protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: TOL2_C38050
symbol: rlmN2
gene_biotype: protein_coding
description:
  RlmN2: ribosomal RNA large subunit methyltransferase N; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.


ensembl_gene_id: TOL2_C38090
symbol: dacA
gene_biotype: protein_coding
description:
  Conserved uncharacterized protein, DUF147; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.


ensembl_gene_id: TOL2_C38150
symbol: nadE
gene_biotype: protein_coding
description:
  NadE: NH3-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.


ensembl_gene_id: TOL2_C38170
symbol: bioD
gene_biotype: protein_coding
description:
  BioD: dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.


ensembl_gene_id: TOL2_C38190
symbol: bioA
gene_biotype: protein_coding
description:
  BioA: predicted adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.


ensembl_gene_id: TOL2_C38290
symbol: bioB
gene_biotype: protein_coding
description:
  BioB: biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.


ensembl_gene_id: TOL2_C38340
symbol: fabB
gene_biotype: protein_coding
description:
  FabB: beta-ketoacyl-acyl-carrier-protein synthase I; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: TOL2_C38350
symbol: acpP2
gene_biotype: protein_coding
description:
  AcpP2: acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.


ensembl_gene_id: TOL2_C38380
symbol: CCK81994.1
gene_biotype: protein_coding
description:
  Outer membrane lipoprotein carrier protein, related to LolA; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).


ensembl_gene_id: TOL2_C38460
symbol: fabF
gene_biotype: protein_coding
description:
  FabF: beta-ketoacyl-acyl-carrier-protein synthase II; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: TOL2_C38550
symbol: fabF2
gene_biotype: protein_coding
description:
  FabF2: beta-ketoacyl-acyl-carrier-protein synthase II; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: TOL2_C38590
symbol: prmA2
gene_biotype: protein_coding
description:
  PrmA2: ribosomal protein L11 methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family.


ensembl_gene_id: TOL2_C38640
symbol: priA
gene_biotype: protein_coding
description:
  PriA: primosomal protein N?; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.


ensembl_gene_id: TOL2_C38790
symbol: metF7
gene_biotype: protein_coding
description:
  MetF7: 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.


ensembl_gene_id: TOL2_C38820
symbol: punA
gene_biotype: protein_coding
description:
  PunA: purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.


ensembl_gene_id: TOL2_C38860
symbol: leuD-2
gene_biotype: protein_coding
description:
  LeuD: 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.


ensembl_gene_id: TOL2_C38870
symbol: ppnK
gene_biotype: protein_coding
description:
  PpnK: predicted inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.


ensembl_gene_id: TOL2_C38880
symbol: polA
gene_biotype: protein_coding
description:
  PolA: DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.


ensembl_gene_id: TOL2_C38900
symbol: purN
gene_biotype: protein_coding
description:
  PurN: phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.


ensembl_gene_id: TOL2_C39040
symbol: CCK82060.1
gene_biotype: protein_coding
description:
  Predicted oligopeptide/dipeptide ABC transporter, ATPase subunit; Belongs to the ABC transporter superfamily.


ensembl_gene_id: TOL2_C39060
symbol: aroB
gene_biotype: protein_coding
description:
  AroB: 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).


ensembl_gene_id: TOL2_C39100
symbol: minC
gene_biotype: protein_coding
description:
  MinC: septum site-determining protein; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family.


ensembl_gene_id: TOL2_C39120
symbol: minE
gene_biotype: protein_coding
description:
  MinE: cell division topolofgical specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.


ensembl_gene_id: TOL2_C39130
symbol: msrAB
gene_biotype: protein_coding
description:
  MsrAB: peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.


ensembl_gene_id: TOL2_C39190
symbol: hysB
gene_biotype: protein_coding
description:
  HysB: periplasmic [NiFeSe] hydrogenase, large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.


ensembl_gene_id: TOL2_C39240
symbol: coaX
gene_biotype: protein_coding
description:
  CoaX: type III pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.


ensembl_gene_id: TOL2_C39260
symbol: folP
gene_biotype: protein_coding
description:
  FolP: dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.


ensembl_gene_id: TOL2_C39270
symbol: ftsH
gene_biotype: protein_coding
description:
  FtsH: cell division protease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family.  In the central section; belongs to the AAA ATPase family.


ensembl_gene_id: TOL2_C39280
symbol: tilS
gene_biotype: protein_coding
description:
  TilS: tRNA(Ile)-lysidine synthase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.


ensembl_gene_id: TOL2_C39290
symbol: mqnD
gene_biotype: protein_coding
description:
  Conserved uncharacterized protein, DUF191; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily.


ensembl_gene_id: TOL2_C39300
symbol: uvrA-2
gene_biotype: protein_coding
description:
  UvrA: excinuclease UvrABC, subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.


ensembl_gene_id: TOL2_C39360
symbol: pbpB
gene_biotype: protein_coding
description:
  PbpB: penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).


ensembl_gene_id: TOL2_C39640
symbol: CCK82119.1
gene_biotype: protein_coding
description:
  TonB related protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.


ensembl_gene_id: TOL2_C39740
symbol: cobT-2
gene_biotype: protein_coding
description:
  CobT2:nicotinate-nucleotide-- dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).


ensembl_gene_id: TOL2_C39770
symbol: hisD
gene_biotype: protein_coding
description:
  HisD: histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.


ensembl_gene_id: TOL2_C39790
symbol: aspS2
gene_biotype: protein_coding
description:
  AspS2: aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.


ensembl_gene_id: TOL2_C39860
symbol: cobU
gene_biotype: protein_coding
description:
  CobU: predicted bifunctional adenosylcobalamin biosynthesis protein; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.


ensembl_gene_id: TOL2_C39880
symbol: cobS
gene_biotype: protein_coding
description:
  CobS: cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.


ensembl_gene_id: TOL2_C39900
symbol: cbiB
gene_biotype: protein_coding
description:
  CbiB: cobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.


ensembl_gene_id: TOL2_C39940
symbol: ispG
gene_biotype: protein_coding
description:
  IspG: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family.


ensembl_gene_id: TOL2_C39950
symbol: proS
gene_biotype: protein_coding
description:
  ProS: prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).


ensembl_gene_id: TOL2_C39960
symbol: relA
gene_biotype: protein_coding
description:
  RelA: GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.


ensembl_gene_id: TOL2_C39980
symbol: gap2
gene_biotype: protein_coding
description:
  Gap2: glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating); Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.


ensembl_gene_id: TOL2_C40040
symbol: CCK82159.1
gene_biotype: protein_coding
description:
  Predicted peptide chain release factor 2, related to PrfB; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.


ensembl_gene_id: TOL2_C40050
symbol: lnt
gene_biotype: protein_coding
description:
  Lnt: apolipoprotein N-acetyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily.


ensembl_gene_id: TOL2_C40080
symbol: lonA5
gene_biotype: protein_coding
description:
  Lon5: ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.


ensembl_gene_id: TOL2_C40090
symbol: rlpA
gene_biotype: protein_coding
description:
  RlpA: rare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.


ensembl_gene_id: TOL2_C40110
symbol: recD2
gene_biotype: protein_coding
description:
  RecD2: helicase, RecD/TraA family; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily.


ensembl_gene_id: TOL2_C40300
symbol: truA3
gene_biotype: protein_coding
description:
  TruA3: tRNA pseudouridine synthase I; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.


ensembl_gene_id: TOL2_C40410
symbol: gdhA3
gene_biotype: protein_coding
description:
  GdhA3: NAD(P)-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.


ensembl_gene_id: TOL2_C40440
symbol: sbcD
gene_biotype: protein_coding
description:
  SbcD: nuclease SbcCD, subunit D; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.


ensembl_gene_id: TOL2_C40530
symbol: argG
gene_biotype: protein_coding
description:
  ArgG: argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.


ensembl_gene_id: TOL2_C40940
symbol: mtdC2
gene_biotype: protein_coding
description:
  MtdC2: multidrug resistande protein, AcrB/AcrD/AcrF family; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: TOL2_C40950
symbol: mtdA2
gene_biotype: protein_coding
description:
  MdtA2: predicted multidrug resistance protein A; Signal peptide; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: TOL2_C40970
symbol: hisHF
gene_biotype: protein_coding
description:
  HisHF: imidazole glycerol phosphate synthase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF; Belongs to the HisA/HisF family.


ensembl_gene_id: TOL2_C41030
symbol: rnpA
gene_biotype: protein_coding
description:
  RnpA: ribonuclease P; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.


ensembl_gene_id: TOL2_C41040
symbol: CCK82260.1
gene_biotype: protein_coding
description:
  Conserved uncharacterized protein, DUF37; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family.


ensembl_gene_id: TOL2_C41050
symbol: oxaA
gene_biotype: protein_coding
description:
  OxaA: inner membrane protein; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.


ensembl_gene_id: TOL2_C41070
symbol: mnmE
gene_biotype: protein_coding
description:
  MnmE: tRNA modification GTPase; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.


ensembl_gene_id: TOL2_C41130
symbol: ssb
gene_biotype: protein_coding
description:
  Ssb: singel-stranded DNA-binding protein, helix-destabilizing; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.


ensembl_gene_id: TOL2_C41150
symbol: rocD
gene_biotype: protein_coding
description:
  RocD: ornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: TOL2_C41270
symbol: trpB2
gene_biotype: protein_coding
description:
  TrpB2: tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.


ensembl_gene_id: TOL2_C41280
symbol: trpA
gene_biotype: protein_coding
description:
  TrpA: tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.


ensembl_gene_id: TOL2_C41390
symbol: bamFG2
gene_biotype: protein_coding
description:
  BamFG2: methyl-viologen-reducing hydrogenase domain modulated NADH-quinone oxidoreductase, subunit E.


ensembl_gene_id: TOL2_C41620
symbol: padB2
gene_biotype: protein_coding
description:
  PadB2: phenylacetyl-CoA:acceptor oxidoreductase, subunit B; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: TOL2_C41730
symbol: moeA2
gene_biotype: protein_coding
description:
  MoeA2: molybdopterin biosynthesis protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.


ensembl_gene_id: TOL2_C41750
symbol: CCK82331.1
gene_biotype: protein_coding
description:
  Molybdopterin binding domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.


ensembl_gene_id: TOL2_C41760
symbol: fdhD3
gene_biotype: protein_coding
description:
  FdhD3: formate dehydrogenase family accessory proten; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.


ensembl_gene_id: TOL2_C41880
symbol: recD-2
gene_biotype: protein_coding
description:
  RecD: exodeoxyribonuclease V, alpha subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination [...]


ensembl_gene_id: TOL2_C41890
symbol: recB
gene_biotype: protein_coding
description:
  RecB: exodeoxyribonuclease V, beta subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination  [...]


ensembl_gene_id: TOL2_C41900
symbol: recC
gene_biotype: protein_coding
description:
  RecC: exodeoxyribonuclease V, gamma subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination [...]


ensembl_gene_id: TOL2_C42300
symbol: cusA
gene_biotype: protein_coding
description:
  CusA: cation efflux system protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: TOL2_C42390
symbol: mtnA
gene_biotype: protein_coding
description:
  MtnA: methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).


ensembl_gene_id: TOL2_C42410
symbol: CCK82397.1
gene_biotype: protein_coding
description:
  RNA polymerase sigma factor related to sigma70; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: TOL2_C42650
symbol: ihfA
gene_biotype: protein_coding
description:
  IhfA: integration host factor, alpha subunit; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.


ensembl_gene_id: TOL2_C42810
symbol: glnD
gene_biotype: protein_coding
description:
  GlnD: [protein PII] uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.


ensembl_gene_id: TOL2_C42820
symbol: tatA2
gene_biotype: protein_coding
description:
  TatA2: twin-arginine translocation protein, TatA/E family subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.


ensembl_gene_id: TOL2_C42870
symbol: ftsX
gene_biotype: protein_coding
description:
  FtsX: cell division protein, predicted permease; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.


ensembl_gene_id: TOL2_C42960
symbol: modB3
gene_biotype: protein_coding
description:
  ModB3: predicted molybdenum transport system permease protein; Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: TOL2_C42970
symbol: modC3
gene_biotype: protein_coding
description:
  ModC2: molybdate ABC transporter, ATP-binding protein; Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Molybdate importer (TC 3.A.1.8) family.


ensembl_gene_id: TOL2_C42990
symbol: purF2
gene_biotype: protein_coding
description:
  PurF2: amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.


ensembl_gene_id: TOL2_C43030
symbol: tkt
gene_biotype: protein_coding
description:
  Tkt: transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.


ensembl_gene_id: TOL2_C43060
symbol: rimO
gene_biotype: protein_coding
description:
  RimO: ribosomal protein S12 methylthiotransferase; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily.


ensembl_gene_id: TOL2_C43290
symbol: glnE
gene_biotype: protein_coding
description:
  GlnE: glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal  [...]


ensembl_gene_id: TOL2_C43320
symbol: ade2
gene_biotype: protein_coding
description:
  Ade2: adenine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.


ensembl_gene_id: TOL2_C43380
symbol: cbiL
gene_biotype: protein_coding
description:
  CbiL: cobalt-precorrin-2 C(20)-methyltransferase; Belongs to the precorrin methyltransferase family.


ensembl_gene_id: TOL2_C43440
symbol: cobO
gene_biotype: protein_coding
description:
  CobO: cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.


ensembl_gene_id: TOL2_C43450
symbol: cobQ
gene_biotype: protein_coding
description:
  CobQ: cobyrinic acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.


ensembl_gene_id: TOL2_C43470
symbol: CCK82503.1
gene_biotype: protein_coding
description:
  2?-5?RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family.


ensembl_gene_id: TOL2_C43490
symbol: moeA3
gene_biotype: protein_coding
description:
  MoeA3: molybdopterin biosynthesis protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.


ensembl_gene_id: TOL2_C43570
symbol: moeA4
gene_biotype: protein_coding
description:
  MoeA4: molybdopterin biosynthesis protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.


ensembl_gene_id: TOL2_C43670
symbol: panB
gene_biotype: protein_coding
description:
  PanB: 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.


ensembl_gene_id: TOL2_C43710
symbol: rsmA
gene_biotype: protein_coding
description:
  RsmA: ribosomal RNA small subunit methyltransferase A; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.


ensembl_gene_id: TOL2_C43780
symbol: alr
gene_biotype: protein_coding
description:
  Alr: alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.


ensembl_gene_id: TOL2_C43805
symbol: panC
gene_biotype: protein_coding
description:
  PanC: pantoate-beta-alanine ligase (AMP-forming); Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.


ensembl_gene_id: TOL2_C43840
symbol: CCK82542.1
gene_biotype: protein_coding
description:
  Conserved uncharacterized protein, related to SirA; Belongs to the sulfur carrier protein TusA family.


