# geneInfo

ensembl_gene_id: SCAB_0031
symbol: ttrA1
gene_biotype: protein_coding
description:
  Putative helicase-like protein; PMID:12127493; PMID:10784050; many more matches amongst Streptomyces genus; cluster 0307 with SCAB91041.


ensembl_gene_id: SCAB_0041
symbol: SCAB_0041
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; PMID:12618462; match to A. nicotinovorans plasmid not significant but circumstantial evidence - SCAB0051, SCAB0061 also hit same sequence; cluster 0308 with SCAB91031.


ensembl_gene_id: SCAB_0051
symbol: SCAB_0051
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; PMID:12618462; PMID:12923100; PMID:16547041; cluster 0309 with SCAB91021; SCAB0041 and SCAB0061 also have similarity to A. nicotinovorans plasmid.


ensembl_gene_id: SCAB_0061
symbol: SCAB_0061
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; PMID:12618462; cluster 0310 with SCAB91011; SCAB0041 and SCAB0051 also have similarity to A. nicotinovorans plasmid; note codon 5 TTA-Leu BldA target; TTA-Leu codon(s) 5 may indicate regulation by BldA.


ensembl_gene_id: SCAB_0071
symbol: SCAB_0071
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; PMID: 6318753; nearest match sequenced as part of S. hygroscopicus hygromycin B biosynthesis cluster; cluster 0311 with SCAB91001.


ensembl_gene_id: SCAB_0161
symbol: SCAB_0161
gene_biotype: protein_coding
description:
  Putative IS transposase; PMID:1650732; PMID:16208464; see also SCAB0171, SCAB42801/42811, SCAB44411/SCAB44421, same pattern of apparent overlap; TTA-Leu codon(s) 101 may indicate regulation by BldA.


ensembl_gene_id: SCAB_0171
symbol: SCAB_0171
gene_biotype: protein_coding
description:
  Conserved hypothetical protein, IS-associated; PMID:1650732; association with SCAB0161 suggested IS involvement, see also SCAB42801/42811, SCAB44411/SCAB44421.


ensembl_gene_id: SCAB_0261
symbol: SCAB_0261
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; PMID:12127493; TTA-Leu codon(s) 4, 87, 403 may indicate regulation by BldA.


ensembl_gene_id: SCAB_0321
symbol: tpgL
gene_biotype: protein_coding
description:
  Terminal protein TpgL; PMID:12651895; PMID:11410532; PMID:11985710; PMID:12127493; many sequenced similar found on unpublished Streptomyces plasmids found in INSDB.


ensembl_gene_id: SCAB_0371
symbol: SCAB_0371
gene_biotype: protein_coding
description:
  Putative IS transposase; PMID:1332944; overlaps SCAB0372 seems to be common pattern see also SCAB0691, SCAB0991, SCAB23721, SCAB42901, SCAB90821; TTA-Leu codon(s) 4 may indicate regulation by BldA.


ensembl_gene_id: SCAB_0372
symbol: SCAB_0372
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Maybe missing stop codon, overlaps see SCAB0371 putative IS transposase.


ensembl_gene_id: SCAB_0471
symbol: SCAB_0471
gene_biotype: protein_coding
description:
  Conserved hypothetical protein, IS-associated; PMID:16208464; PMID:1650732; see SCAB0461; TTA-Leu codon(s) 12 may indicate regulation by BldA.


ensembl_gene_id: SCAB_0691
symbol: SCAB_0691
gene_biotype: protein_coding
description:
  Putative IS transposase; PMID:1332944; overlaps SCAB0692 seems to be common pattern see also SCAB0371, SCAB0991, SCAB23721, SCAB42901, SCAB90821.


ensembl_gene_id: SCAB_0692
symbol: SCAB_0692
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Possible coiled-coil region aa23-52; overlaps see SCAB0691 putative IS transposase.


ensembl_gene_id: SCAB_0701
symbol: SCAB_0701
gene_biotype: protein_coding
description:
  Putative IS transposase; PMID:15686551; overlaps 0692 maybe pseudo; strong match to gene on S. turgidiscabies PAI.


ensembl_gene_id: SCAB_0721
symbol: SCAB_0721
gene_biotype: protein_coding
description:
  Putative oxidoreductase; PF00441 and PF08028 fatty acid oxidation; may suggest role in secondary metabolite synthesis for instance PMID: 15942003.


ensembl_gene_id: SCAB_0731
symbol: SCAB_0731
gene_biotype: protein_coding
description:
  Putative phosphopantetheinyl transferase; PMID:11390684; domain prediction suggests cds may be fragment of secondary metabolism biosynthesis cluster see also SCAB0721, SCAB0751; Belongs to the P-Pant transferase superfamily.


ensembl_gene_id: SCAB_0751
symbol: SCAB_0751
gene_biotype: protein_coding
description:
  Putative AMP-binding protein; PMID:10930733; PMID:11048953; domain prediction suggests cds may be fragment of secondary metabolism biosynthesis cluster see also SCAB0731, SCAB0721; Belongs to the ATP-dependent AMP-binding enzyme family.


ensembl_gene_id: SCAB_0771
symbol: SCAB_0771
gene_biotype: protein_coding
description:
  Putative aminotransferase; PMID:15128576; related to ectoine biosynthesis aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: SCAB_0991
symbol: SCAB_0991
gene_biotype: protein_coding
description:
  Putative IS transposase; PMID:1332944; see also SCAB0371, SCAB0691, SCAB23721, SCAB42901, SCAB90821; TTA-Leu codon(s) 4 may indicate regulation by BldA.


ensembl_gene_id: SCAB_10021
symbol: CBG68179.1
gene_biotype: protein_coding
description:
  Putative transposase; PMID: 9862476; PMID:8973350; PMID:7518087; see also SCAB0831, SCAB1341, SCAB81311.


ensembl_gene_id: SCAB_10091
symbol: CBG68185.1
gene_biotype: protein_coding
description:
  Putative transcriptional regulator, AraC family; TTA-Leu codon(s) 103 may indicate regulation by BldA.


ensembl_gene_id: SCAB_10251
symbol: CBG68200.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.


ensembl_gene_id: SCAB_10521
symbol: CBG68225.1
gene_biotype: protein_coding
description:
  Putative oxidoreductase; Cluster 0095 with SCAB4751, SCAB69701, SCAB83281 gap1/2; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.


ensembl_gene_id: SCAB_10711
symbol: CBG68242.1
gene_biotype: protein_coding
description:
  Putative oxidoreductase; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family.


ensembl_gene_id: SCAB_10751
symbol: narG2
gene_biotype: protein_coding
description:
  Nitrate reductase alpha chain NarG2; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: SCAB_10801
symbol: CBG68250.1
gene_biotype: protein_coding
description:
  Putative transposase; PMID:1847988; PMID:11985710; PMID:7961479; PMID:8088548; PMID:15686551; see also SCAB90021; TTA-Leu codon(s) 87 may indicate regulation by BldA.


ensembl_gene_id: SCAB_10961
symbol: ufaA1
gene_biotype: protein_coding
description:
  PROBABLE CYCLOPROPANE-FATTY-ACYL-PHOSPHOLIPID SYNTHASE UFAA1 (CYCLOPROPANE FATTY ACID SYNTHASE) (CFA SYNTHASE).


ensembl_gene_id: SCAB_11091
symbol: def-2
gene_biotype: protein_coding
description:
  Polypeptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.


ensembl_gene_id: SCAB_11211
symbol: egtA
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low- molecular thiol compound ergothioneine.


ensembl_gene_id: SCAB_11221
symbol: egtB
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family.


ensembl_gene_id: SCAB_11231
symbol: egtC
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine.


ensembl_gene_id: SCAB_11241
symbol: egtD
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the SAM-dependent triple methylation of the alpha- amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine; Belongs to the methyltransferase superfamily. EgtD family.


ensembl_gene_id: SCAB_1131
symbol: SCAB_1131
gene_biotype: protein_coding
description:
  Putative inositol-1-monophosphatase; Function of phosphatidylinositol in mycobacteria: PMID: 15634688.


ensembl_gene_id: SCAB_1141
symbol: SCAB_1141
gene_biotype: protein_coding
description:
  Putative LysR family transcriptional regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: SCAB_11411
symbol: CBG68309.1
gene_biotype: protein_coding
description:
  Putative thiamine biosynthesis lipoprotein precursor; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.


ensembl_gene_id: SCAB_11491
symbol: CBG68317.1
gene_biotype: protein_coding
description:
  Putative lysR-family transcriptional regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: SCAB_11701
symbol: CBG68338.1
gene_biotype: protein_coding
description:
  Putative transposase; Cluster 0025 8: SCAB3371, SCAB4481, SCAB7601, SCAB11701, SCAB20281, SCAB40511, SCAB68181.


ensembl_gene_id: SCAB_11761
symbol: glgC
gene_biotype: protein_coding
description:
  Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.


ensembl_gene_id: SCAB_11811
symbol: CBG68349.1
gene_biotype: protein_coding
description:
  6-phosphogluconate 1-dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.


ensembl_gene_id: SCAB_11841
symbol: panD
gene_biotype: protein_coding
description:
  L-aspartate-alpha-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.


ensembl_gene_id: SCAB_11921
symbol: CBG68360.1
gene_biotype: protein_coding
description:
  Putative ATP-binding biosynthetic enzyme; PMID: 14693539; cluster 0166 with SCAB22041 and SCAB32621.


ensembl_gene_id: SCAB_11971
symbol: CBG68365.1
gene_biotype: protein_coding
description:
  Putative AfsR-family regulatory protein; PMID:16207901; PMID:15113000; PMID:10517581; many more related matches amongst streptomycetes.


ensembl_gene_id: SCAB_12021
symbol: CBG68370.1
gene_biotype: protein_coding
description:
  Putative aldolase; PMID: 21475791; PMID:10103039; PMID:12819191; PMID:9426000; cluster 0167 with SCAB67661 and SCAB1981; Belongs to the class-II DAHP synthase family.


ensembl_gene_id: SCAB_12031
symbol: CBG68371.1
gene_biotype: protein_coding
description:
  2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase; PMID:11029592; PMID:8921902; PMID:2521622; PMID:9371453; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: SCAB_12071
symbol: CBG68375.1
gene_biotype: protein_coding
description:
  Putative oxidoreductase; PMID:10792718; PMID:16228193; cluster 0168 with SCAB2261 and SCAB79721; substrate maybe related to levodione.


ensembl_gene_id: SCAB_12081
symbol: CBG68376.1
gene_biotype: protein_coding
description:
  Putative AfsA/ScbA-like protein; PMID:9371444; PMID:10767533; PMID:15797213; PMID:12904539; PMID:2492509; PMID:16228193.


ensembl_gene_id: SCAB_12091
symbol: CBG68377.1
gene_biotype: protein_coding
description:
  Putative gamma-butyrolactone binding protein; PMID:7592371; PMID:11557748; PMID:9260956; PMID:16228193; PMID:7744885.


ensembl_gene_id: SCAB_12111
symbol: CBG68379.1
gene_biotype: protein_coding
description:
  Putative secondary metabolite regulator; PMID:10467127; PMID:15797213; PMID:12183628; PMID:3036668; PMID:12127493.


ensembl_gene_id: SCAB_12241
symbol: CBG68390.1
gene_biotype: protein_coding
description:
  Putative secreted protein; No significant db matches; TTA-Leu codon(s) 8 may indicate regulation by BldA.


ensembl_gene_id: SCAB_1231
symbol: SCAB_1231
gene_biotype: protein_coding
description:
  Putative ATP-binding protein; Product inferred from PF03796 ATP-binding function; no full-length matches in db.


ensembl_gene_id: SCAB_12431
symbol: whiB-2
gene_biotype: protein_coding
description:
  Putative transcriptional regulator; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.


ensembl_gene_id: SCAB_12661
symbol: CBG68426.1
gene_biotype: protein_coding
description:
  Putative LysR-family transcriptional regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: SCAB_12671
symbol: kbl
gene_biotype: protein_coding
description:
  2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.


ensembl_gene_id: SCAB_12681
symbol: tdh
gene_biotype: protein_coding
description:
  Threonine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate.; Belongs to the zinc-containing alcohol dehydrogenase family.


ensembl_gene_id: SCAB_12781
symbol: CBG68437.1
gene_biotype: protein_coding
description:
  Putative short-chain dehydrogenase/oxidoreductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: SCAB_12901
symbol: CBG68449.1
gene_biotype: protein_coding
description:
  Putative aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: SCAB_12911
symbol: dxs1
gene_biotype: protein_coding
description:
  Putative 1-deoxy-D-xylulose-5-phosphate synthase 1; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.


ensembl_gene_id: SCAB_12921
symbol: ispG
gene_biotype: protein_coding
description:
  Putative 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family.


ensembl_gene_id: SCAB_13071
symbol: CBG68465.1
gene_biotype: protein_coding
description:
  Putative integral membrane transferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: SCAB_13111
symbol: idi
gene_biotype: protein_coding
description:
  Putative IPP isomerase; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).


ensembl_gene_id: SCAB_13241
symbol: rbsD
gene_biotype: protein_coding
description:
  High affinity ribose transport protein RbsD; Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.


ensembl_gene_id: SCAB_13251
symbol: rbsK
gene_biotype: protein_coding
description:
  Putative ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.


ensembl_gene_id: SCAB_13271
symbol: CBG68485.1
gene_biotype: protein_coding
description:
  Putative sugar ABC transport system, permease protein; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: SCAB_13331
symbol: CBG68491.1
gene_biotype: protein_coding
description:
  Putative ATP synthase B chain; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). Belongs to the ATPase B chain family.


ensembl_gene_id: SCAB_13401
symbol: nfi
gene_biotype: protein_coding
description:
  Putative endonuclease; DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.


ensembl_gene_id: SCAB_13861
symbol: CBG68540.1
gene_biotype: protein_coding
description:
  PROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: SCAB_1391
symbol: SCAB_1391
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Cluster 0386 with SCAB77921; TTA-Leu codon(s) 222 may indicate regulation by BldA.


ensembl_gene_id: SCAB_1401
symbol: SCAB_1401
gene_biotype: protein_coding
description:
  Putative TetR-family regulator; PMID:15271354; PMID:9512878; PMID:1878971; PMID:10767533; PMID:11050092; cluster 0388 with SCAB1731.


ensembl_gene_id: SCAB_14061
symbol: CBG68557.1
gene_biotype: protein_coding
description:
  Putative PROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: SCAB_14161
symbol: SCAB_14161
gene_biotype: protein_coding
description:
  Putative insertion element protein (fragment); PMID:1700062; from fasta search looks like fragment; Belongs to the amidase family.


ensembl_gene_id: SCAB_14201
symbol: CBG68571.1
gene_biotype: protein_coding
description:
  Putative oligopeptide ABC transporter, ATP-binding protein; Belongs to the ABC transporter superfamily.


ensembl_gene_id: SCAB_14231
symbol: CBG68574.1
gene_biotype: protein_coding
description:
  Putative PROBABLE FATTY-ACID-CoA LIGASE FADD35 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE).


ensembl_gene_id: SCAB_14321
symbol: CBG68582.1
gene_biotype: protein_coding
description:
  Putative transposase; PMID:16305230; PMID: 2821490; see also SCAB21921, SCAB33271, SCAB77071; strong blastn hits to S. turgidiscabies PAI, 36% aa_id to transposase on S. turgidiscabies PAI.


ensembl_gene_id: SCAB_14331
symbol: CBG68583.1
gene_biotype: protein_coding
description:
  AcrB/AcrD/AcrF family protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: SCAB_14531
symbol: SCAB_14531
gene_biotype: protein_coding
description:
  Putative transposase; PMID: 12791134; pseudo: frameshift after codon 165. See also SCAB0401, SCAB40521, SCAB42871.


ensembl_gene_id: SCAB_14601
symbol: CBG68608.1
gene_biotype: protein_coding
description:
  Putative transposase; PMID:16208464; PMID:14702401; found near at least 2 antibiotic biosynthesis clusters (PMID:16208464, PMID:14702401); cluster 0034: SCAB14601, SCAB16631, SCAB24421, SCAB30531, SCAB30841, SCAB68821, SCAB87301.


ensembl_gene_id: SCAB_14691
symbol: CBG68616.1
gene_biotype: protein_coding
description:
  Putative IS transposase; PMID:10809688; PMID:3010046; see also SCAB77591; TTA-Leu codon(s) 2 may indicate regulation by BldA.


ensembl_gene_id: SCAB_15001
symbol: mhpA
gene_biotype: protein_coding
description:
  3-(3-hydroxy-phenyl)propionate hydroxylase, FAD/NAD(P)-binding; Annotation transferred from E. coli.


ensembl_gene_id: SCAB_15161
symbol: nbaC
gene_biotype: protein_coding
description:
  Putative 3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family.


ensembl_gene_id: SCAB_15191
symbol: CBG68663.1
gene_biotype: protein_coding
description:
  PROBABLE 4-HYDROXY-2-OXOVALERATE ALDOLASE (HOA); Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family.


ensembl_gene_id: SCAB_15201
symbol: CBG68664.1
gene_biotype: protein_coding
description:
  Putative acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.


ensembl_gene_id: SCAB_15241
symbol: kynU
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively.


ensembl_gene_id: SCAB_1531
symbol: SCAB_1531
gene_biotype: protein_coding
description:
  Putative adenylation protein; PMID:15113000; PMID:15870461; PMID:16208464; may be related to gene cluster SCAB1381-SCAB1481.


ensembl_gene_id: SCAB_15441
symbol: CBG68687.1
gene_biotype: protein_coding
description:
  Putative phosphopantetheinyl transferase; PMID:16207901; PMID:14695521; PMID:21344786; see also SCAB84091, SCAB84081; Belongs to the P-Pant transferase superfamily.


ensembl_gene_id: SCAB_15451
symbol: CBG68688.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; PMID:12115055; PMID: 15844935; PMID:16207901; see also SCAB84091, SCAB84081.


ensembl_gene_id: SCAB_1551
symbol: SCAB_1551
gene_biotype: protein_coding
description:
  Putative adenylation protein; PMID:16208464; PMID:11048953; may be related to gene cluster SCAB1381-1481.


ensembl_gene_id: SCAB_1561
symbol: SCAB_1561
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; May have class III aminotransferase activity from domain match; similar architecture to Caulobacter Q0M3P5 (36% aa_id).


ensembl_gene_id: SCAB_15681
symbol: CBG68710.1
gene_biotype: protein_coding
description:
  Binding-protein-dependent transport system, secreted component; Some similarity to cysteine-binding protein FliY from S. typhimurium.


ensembl_gene_id: SCAB_1571
symbol: SCAB_1571
gene_biotype: protein_coding
description:
  Putative phosphopantetheine-binding carrier protein; No significant db matches, may be related to gene cluster SCAB1381-SCAB1481.


ensembl_gene_id: SCAB_15721
symbol: tal
gene_biotype: protein_coding
description:
  Putative transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily.


ensembl_gene_id: SCAB_15731
symbol: zwf-2
gene_biotype: protein_coding
description:
  Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.


ensembl_gene_id: SCAB_15781
symbol: aroE
gene_biotype: protein_coding
description:
  Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).


ensembl_gene_id: SCAB_1581
symbol: SCAB_1581
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Some similar proteins are annotated as phosphopantetheinyl transferases, )BAF92600, EDP57114) but no conserved domain found; may be related to gene cluster SCAB1381-1481.


ensembl_gene_id: SCAB_15891
symbol: ribA
gene_biotype: protein_coding
description:
  GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family.


ensembl_gene_id: SCAB_15961
symbol: CBG68737.1
gene_biotype: protein_coding
description:
  Putative integral membrane protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: SCAB_16271
symbol: CBG68763.1
gene_biotype: protein_coding
description:
  Hypothetical protein; No significant db matches; TTA-Leu codon(s) 56 may indicate regulation by BldA.


ensembl_gene_id: SCAB_16361
symbol: CBG68771.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; No full-length matches; TTA-Leu codon(s) 33 may indicate regulation by BldA.


ensembl_gene_id: SCAB_16531
symbol: fusB
gene_biotype: protein_coding
description:
  Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.


ensembl_gene_id: SCAB_16571
symbol: sucD-2
gene_biotype: protein_coding
description:
  Succinyl-coa synthetase alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.


ensembl_gene_id: SCAB_16581
symbol: sucC-2
gene_biotype: protein_coding
description:
  Succinyl-coa synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.


ensembl_gene_id: SCAB_16601
symbol: frc
gene_biotype: protein_coding
description:
  Putative transferase; Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl- CoA to oxalate; Belongs to the CoA-transferase III family. Frc subfamily.


ensembl_gene_id: SCAB_1661
symbol: SCAB_1661
gene_biotype: protein_coding
description:
  Putative luxR family regulator; PMID:7868594; PMID:10206788; TTA-Leu codon(s) 16 may indicate regulation by BldA.


ensembl_gene_id: SCAB_16631
symbol: CBG68797.1
gene_biotype: protein_coding
description:
  Putative transposase; PMID:16208464; PMID:14702401; cluster 0034: SCAB14601, SCAB16631, SCAB24421, SCAB30531, SCAB30841, SCAB68821, SCAB87301; found near at least 2 antibiotic biosynthesis clusters.


ensembl_gene_id: SCAB_16641
symbol: CBG68798.1
gene_biotype: protein_coding
description:
  Putative transposase related protein; PMID:16208464; PMID:14702401; cluster 0050 6: SCAB16641, SCAB24431, SCAB30541, SCAB30831, SCAB68821, SCAB87291.


ensembl_gene_id: SCAB_16761
symbol: CBG68810.1
gene_biotype: protein_coding
description:
  ABC transporter integral membrane protein; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: SCAB_16801
symbol: fabH-2
gene_biotype: protein_coding
description:
  3-oxoacyl-[acyl-carrier-protein] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.


ensembl_gene_id: SCAB_16881
symbol: CBG68820.1
gene_biotype: protein_coding
description:
  Putative respiratory chain oxidoreductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: SCAB_16911
symbol: fdhD-2
gene_biotype: protein_coding
description:
  Putative protein associated with oxidoreductase activity; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.


ensembl_gene_id: SCAB_17091
symbol: dnaK-3
gene_biotype: protein_coding
description:
  Putative heat shock protein 70 (fragment); Acts as a chaperone; Belongs to the heat shock protein 70 family.


ensembl_gene_id: SCAB_17331
symbol: gvpJ
gene_biotype: protein_coding
description:
  Putative gas vesicle synthesis protein; Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth.


ensembl_gene_id: SCAB_17381
symbol: gvpA
gene_biotype: protein_coding
description:
  Putative gas vesicle synthesis protein; Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth. GvpA type proteins form the essential core of the structure.


ensembl_gene_id: SCAB_17681
symbol: CBG68898.1
gene_biotype: protein_coding
description:
  Putative phosphatidylserine synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: SCAB_17781
symbol: CBG68908.1
gene_biotype: protein_coding
description:
  Putative methylated-DNA-protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.


ensembl_gene_id: SCAB_17851
symbol: CBG68915.1
gene_biotype: protein_coding
description:
  Putative oxygenase; PMID:16269733; PMID:2345149; PMID:7557483; PMID:15561847; PMID:15752735; Belongs to the cytochrome P450 family.


ensembl_gene_id: SCAB_17911
symbol: CBG68921.1
gene_biotype: protein_coding
description:
  Putative membrane protein; N terminal extent by first start before expressed tryptic fragment site; TTA-Leu codon(s) 7 may indicate regulation by BldA.


ensembl_gene_id: SCAB_17931
symbol: CBG68923.1
gene_biotype: protein_coding
description:
  Putative inositol monophosphatase; PMID:10858335; Function of phosphatidylinositol in mycobacteria: PMID: 15634688.


ensembl_gene_id: SCAB_17951
symbol: CBG68925.1
gene_biotype: protein_coding
description:
  Putative SAM-dependent methyltransferase; Cluster 0447 with SCAB21871; TTA-Leu codon(s) 4 may indicate regulation by BldA.


ensembl_gene_id: SCAB_18021
symbol: CBG68932.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: SCAB_18061
symbol: map2
gene_biotype: protein_coding
description:
  Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.


ensembl_gene_id: SCAB_18371
symbol: CBG68964.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Possible NIS system, nearby genes SCAB18311, SCAB18321 for AMP catabolism.


ensembl_gene_id: SCAB_18391
symbol: CBG68966.1
gene_biotype: protein_coding
description:
  Putative siderophore biosynthesis protein; Possible NIS system, nearby genes SCAB18311, SCAB18321 for AMP catabolism.


ensembl_gene_id: SCAB_18411
symbol: CBG68968.1
gene_biotype: protein_coding
description:
  Putative secreted protein; Possible NIS system, nearby genes SCAB18311, SCAB18321 for AMP catabolism.


ensembl_gene_id: SCAB_1851
symbol: SCAB_1851
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; PMID:1135118; PMID:14769868; strong matches to characterised gene S. platensis L-glutamate oxidase. Appears pseudo due to two frameshift nonsense mutations (after codons 47 and 188), an opal stop by codon 575.


ensembl_gene_id: SCAB_18521
symbol: CBG68979.1
gene_biotype: protein_coding
description:
  Putative uricase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.


ensembl_gene_id: SCAB_18531
symbol: CBG68980.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.


ensembl_gene_id: SCAB_18811
symbol: CBG69006.1
gene_biotype: protein_coding
description:
  Putative LacI family transcriptional regulator; PMID: 15686551; PMID:8407808; strong match to S. turgidiscabies pathogenicity island.


ensembl_gene_id: SCAB_19041
symbol: CBG69027.1
gene_biotype: protein_coding
description:
  Probable ABC transport protein, membrane component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: SCAB_19151
symbol: CBG69037.1
gene_biotype: protein_coding
description:
  Putative binding-protein-dependent transport system inner membrane subunit; PMID: 11555292; PMID: 11555291; match in Erwinia chrysanthemi is pathogenicity-associated pectic oligo uptake transporter.


ensembl_gene_id: SCAB_19171
symbol: CBG69039.1
gene_biotype: protein_coding
description:
  Putative secreted substrate-binding protein (transport sysetm associated); PMID: 11555292; PMID: 11555291; match in Erwinia chrysanthemi is pathogenicity-associated pectic oligo uptake transporter.


ensembl_gene_id: SCAB_19351
symbol: rsgA
gene_biotype: protein_coding
description:
  Putative ATP GTP-binding protein; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.


ensembl_gene_id: SCAB_19411
symbol: CBG69062.1
gene_biotype: protein_coding
description:
  Putative 2-hydroxyacid-family dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: SCAB_1961
symbol: SCAB_1961
gene_biotype: protein_coding
description:
  Putative molybdopterin-binding oxidoreductase; PMID: 2941757; TTA-Leu codon(s) 23, 354 may indicate regulation by BldA; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: SCAB_1971
symbol: SCAB_1971
gene_biotype: protein_coding
description:
  Putative aminodeoxychorismate synthase; PMID:9044253; PMID:14700630; PMID:14652074; PMID:11782498; PMID:8472954; PMID:15184904; PMID:8704974.


ensembl_gene_id: SCAB_19771
symbol: CBG69097.1
gene_biotype: protein_coding
description:
  Putative nitrite/sulphite reductase; PMID:15111132; PMID:15917234; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.


ensembl_gene_id: SCAB_19791
symbol: cysH
gene_biotype: protein_coding
description:
  Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.


ensembl_gene_id: SCAB_1981
symbol: SCAB_1981
gene_biotype: protein_coding
description:
  Putative aldolase; PMID:8760910; cluster 0167 with SCAB12021 and SCAB67661; Belongs to the class-II DAHP synthase family.


ensembl_gene_id: SCAB_19821
symbol: cysN
gene_biotype: protein_coding
description:
  Sulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.


ensembl_gene_id: SCAB_1991
symbol: acpD
gene_biotype: protein_coding
description:
  Putative acyl carrier protein phosphodiesterase; Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity; Belongs to the azoreductase type 1 family.


ensembl_gene_id: SCAB_19961
symbol: CBG69113.1
gene_biotype: protein_coding
description:
  Putative antibiotic resistance macrolide glycosyltransferase; Belongs to the UDP-glycosyltransferase family.


ensembl_gene_id: SCAB_20041
symbol: CBG69121.1
gene_biotype: protein_coding
description:
  Putative protease inhibitor-like protein; PMID:2732212; Contains hydrophobic region - possible export signal sequence; Belongs to the protease inhibitor I16 (SSI) family.


ensembl_gene_id: SCAB_20311
symbol: CBG69147.1
gene_biotype: protein_coding
description:
  RarC (conservon) homolog; PMID: 12657469; truncated conservon; TTA-Leu codon(s) 14 may indicate regulation by BldA.


ensembl_gene_id: SCAB_20511
symbol: CBG69166.1
gene_biotype: protein_coding
description:
  Putative AfsR-family transcriptional regulator; PMID:14702401; PMID:15113000; PMID:10517581; Possible tandem/partial duplication downstream.


ensembl_gene_id: SCAB_20521
symbol: CBG69167.1
gene_biotype: protein_coding
description:
  Putative AfsR-family transcriptional regulator; Possible tandem/partial duplication from upstream CDS.


ensembl_gene_id: SCAB_20551
symbol: CBG69170.1
gene_biotype: protein_coding
description:
  Putative SelR-type methionine sulfoxide reductase; Belongs to the MsrB Met sulfoxide reductase family.


ensembl_gene_id: SCAB_20611
symbol: CBG69176.1
gene_biotype: protein_coding
description:
  Probable carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family.


ensembl_gene_id: SCAB_20691
symbol: CBG69184.1
gene_biotype: protein_coding
description:
  Possible secreted polysaccharide deacetylase; Matches include putative lipoproteins in S. coelicolor and S. avermitilis.


ensembl_gene_id: SCAB_2071
symbol: mhpE
gene_biotype: protein_coding
description:
  4-hydroxy-2-ketovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family.


ensembl_gene_id: SCAB_20801
symbol: CBG69195.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; PMID:15563836; possibly E.C. 1.13.11: from family similarity to chlorite dismutase 1.13.11.49.


ensembl_gene_id: SCAB_2081
symbol: bphG
gene_biotype: protein_coding
description:
  Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.


ensembl_gene_id: SCAB_20811
symbol: CBG69196.1
gene_biotype: protein_coding
description:
  Putative oxidoreductase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.


ensembl_gene_id: SCAB_20861
symbol: hemE
gene_biotype: protein_coding
description:
  Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.


ensembl_gene_id: SCAB_2091
symbol: mhpD
gene_biotype: protein_coding
description:
  2-keto-4-pentenoate hydratase; Annotation transferred from E. coli perhaps breakdown of aromatics cf PMID:9492273.


ensembl_gene_id: SCAB_20991
symbol: dxs
gene_biotype: protein_coding
description:
  Probable 1-deoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.


ensembl_gene_id: SCAB_21001
symbol: CBG69215.1
gene_biotype: protein_coding
description:
  Probable ABC-type integral membrane transport protein; Cluster 0482 with SCAB43221; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: SCAB_2101
symbol: mhpB
gene_biotype: protein_coding
description:
  2,3-dihydroxyphenylpropionate 1,2-dioxygenase; Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3-dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2-hydroxy-6- ketononatrienedioate, respectively; Belongs to the LigB/MhpB extradiol dioxygenase family.


ensembl_gene_id: SCAB_21081
symbol: CBG69223.1
gene_biotype: protein_coding
description:
  Putative secreted cellulose/chitin binding protein; PMID:9182697; PMID:7815940; PMID:9611804; cluster 0475 with SCAB20161; TTA-Leu codon(s) 8 may indicate regulation by BldA.


ensembl_gene_id: SCAB_21321
symbol: CBG69247.1
gene_biotype: protein_coding
description:
  Putative glutamyl-tRNA synthetase; Cluster 0490 with SCAB26661; Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: SCAB_2141
symbol: hcaB
gene_biotype: protein_coding
description:
  2,3-dihydroxy-2,3-dihydrophenylpropionatedehydr og enase; Annotation transferred from E. coli; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: SCAB_21421
symbol: CBG69257.1
gene_biotype: protein_coding
description:
  Putative deoxygenase; PMID11410376; PMID12725858; TTA-Leu codon(s) 30 may indicate regulation by BldA.


ensembl_gene_id: SCAB_2151
symbol: bphD
gene_biotype: protein_coding
description:
  2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase BphD; Annotation transferred, perhaps biphenyl catabolism cf PMID: 2160220.


ensembl_gene_id: SCAB_21581
symbol: CBG69273.1
gene_biotype: protein_coding
description:
  Putative glutamine synthetase; Cluster 0495 with SCAB73851; Belongs to the glutamine synthetase family.


ensembl_gene_id: SCAB_2161
symbol: hcaF
gene_biotype: protein_coding
description:
  3-phenylpropionate dioxygenase, beta subunit; This operon in E. coli encodes a pathway for catabolism of aromatic acids; annotation transferred from E. coli.


ensembl_gene_id: SCAB_21741
symbol: whiB-4
gene_biotype: protein_coding
description:
  Putative WhiB-like transcription factor; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.


ensembl_gene_id: SCAB_21791
symbol: CBG69294.1
gene_biotype: protein_coding
description:
  Putative mobilisation relaxase component; PMID: 12584005; cluster 0122: SCAB21791, SCAB32311, SCAB48651, SCAB52671.


ensembl_gene_id: SCAB_21831
symbol: CBG69298.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Cluster 0503 with SCAB32341; contains a pair of PF03771 (DUF) see also SCAB22011, SCAB21991, SCAB22431, SCAB22451, SCAB22471, SCAB22511, SCAB22521, SCAB22571.


ensembl_gene_id: SCAB_21871
symbol: CBG69302.1
gene_biotype: protein_coding
description:
  Putative SAM-dependent methyltransferase; Cluster 0447 with SCAB17951; TTA-Leu codon(s) 83 may indicate regulation by BldA.


ensembl_gene_id: SCAB_2191
symbol: hcaE
gene_biotype: protein_coding
description:
  3-phenylpropionate dioxygenase, alpha subunit; Annotation transferred from E. coli, perhaps 3-phenylpropionic acid breakdown cf PMID: 9603882.


ensembl_gene_id: SCAB_21921
symbol: CBG69307.1
gene_biotype: protein_coding
description:
  Putative transposase; PMID:16305230; PMID: 2821490; see also SCAB14321, SCAB33271, SCAB77071; strong blastn hit to S. turgidiscabies PAI; 36% aa_id to transposase on S. turgidiscabies PAI.


ensembl_gene_id: SCAB_21991
symbol: CBG69314.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Cluster 0506 with SCAB32571 which might be frameshifted fragment diverged from SCAB21991; contains a pair of PF03771 (DUF) see also SCAB21831, SCAB22011, SCAB22431, SCAB22451, SCAB22471.


ensembl_gene_id: SCAB_22011
symbol: CBG69316.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Cluster 0508 with SCAB32591; contains a pair of PF03771 (DUF) see also SCAB21831, SCAB21991, SCAB22431, SCAB22451, SCAB22471.


ensembl_gene_id: SCAB_22041
symbol: CBG69319.1
gene_biotype: protein_coding
description:
  Putative ATP-binding biosynthetic enzyme; PMID: 14693539; PMID:11214968; PMID:9163424; cluster 0116 with SCAB32621 and SCAB11921.


ensembl_gene_id: SCAB_2211
symbol: SCAB_2211
gene_biotype: protein_coding
description:
  Putative transcriptional repressor (IclR family); Annotation transferred from E. coli; TTA-Leu codon(s) 276 may indicate regulation by BldA.


ensembl_gene_id: SCAB_22171
symbol: CBG69332.1
gene_biotype: protein_coding
description:
  Putative DNA methylase; Cluster 0522 with SCAB32751; Belongs to the N(4)/N(6)-methyltransferase family.


ensembl_gene_id: SCAB_22221
symbol: CBG69337.1
gene_biotype: protein_coding
description:
  Putative ATP-binding integral membrane protein; MID:15828858; PMID:12589432; cluster 0525 with SCAB32791.


ensembl_gene_id: SCAB_2231
symbol: SCAB_2231
gene_biotype: protein_coding
description:
  Putative transmembrane transport protein; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: SCAB_2241
symbol: SCAB_2241
gene_biotype: protein_coding
description:
  Putative membrane protein; No significant db matches; TTA-Leu codon(s) 30, 134 may indicate regulation by BldA.


ensembl_gene_id: SCAB_22431
symbol: CBG69358.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Contains a pair of PF03771 (DUF) see also SCAB21831, SCAB22011, SCAB21991, SCAB22451, SCAB22471, SCAB22511, SCAB22521, SCAB22571.


ensembl_gene_id: SCAB_22451
symbol: CBG69360.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Contains a pair of PF03771 (DUF) see also SCAB21831, SCAB22011, SCAB21991, SCAB22431, SCAB22471, SCAB22511, SCAB22521, SCAB22571.


ensembl_gene_id: SCAB_22471
symbol: CBG69362.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Contains a pair of PF03771 (DUF) see also SCAB21831, SCAB22011, SCAB21991, SCAB22431, SCAB22451, SCAB22511, SCAB22521, SCAB22571.


ensembl_gene_id: SCAB_22511
symbol: CBG69366.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Contains a pair of PF03771 (DUF) see also SCAB21831, SCAB22011, SCAB21991, SCAB22431, SCAB22451, SCAB22471, SCAB22521, SCAB22571.


ensembl_gene_id: SCAB_22521
symbol: CBG69367.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Contains a pair of PF03771 (DUF) see also SCAB21831, SCAB22011, SCAB21991, SCAB22431, SCAB22451, SCAB22471, SCAB22511, SCAB22571.


ensembl_gene_id: SCAB_22551
symbol: CBG69370.1
gene_biotype: protein_coding
description:
  Putative modification methylase; PMID:2836359; cluster 0544 with SCAB33201; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.


ensembl_gene_id: SCAB_22571
symbol: CBG69372.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Cluster 0546 with SCAB33281; contains a pair of PF03771 (DUF) see also SCAB21831, SCAB22011, SCAB21991, SCAB22431, SCAB22451, SCAB22471, SCAB22511, SCAB22521.


ensembl_gene_id: SCAB_2261
symbol: SCAB_2261
gene_biotype: protein_coding
description:
  Putative oxidoreductase; PMID:11388460; cluster 0168 with SCAB12071 and SCAB79721; substrate maybe related to levodione.


ensembl_gene_id: SCAB_23141
symbol: arcB
gene_biotype: protein_coding
description:
  Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.


ensembl_gene_id: SCAB_23181
symbol: CBG69431.1
gene_biotype: protein_coding
description:
  Putative biosynthetic transferase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.


ensembl_gene_id: SCAB_23271
symbol: CBG69440.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.


ensembl_gene_id: SCAB_23291
symbol: CBG69442.1
gene_biotype: protein_coding
description:
  Putative bifunctional reductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.


ensembl_gene_id: SCAB_23351
symbol: CBG69448.1
gene_biotype: protein_coding
description:
  UDP-glucose/GDP-mannose family dehydrogenase (putative secreted protein); PMID:12644223; PMID:12825356; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.


ensembl_gene_id: SCAB_23481
symbol: CBG69461.1
gene_biotype: protein_coding
description:
  Putative nucleotide sugar epimerase/dehydratase; PMID: 8628239; PMID: 11598046; PMID:12644223; PMID:12825356.


ensembl_gene_id: SCAB_23541
symbol: CBG69467.1
gene_biotype: protein_coding
description:
  Putative aminotransferase; PMID: 11598046; PMID:12644223; PMID:12825356; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: SCAB_23851
symbol: CBG69499.1
gene_biotype: protein_coding
description:
  Putative protein phosphatase; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.


ensembl_gene_id: SCAB_23931
symbol: CBG69507.1
gene_biotype: protein_coding
description:
  Putative tRNA methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.


ensembl_gene_id: SCAB_24021
symbol: dut
gene_biotype: protein_coding
description:
  Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.


ensembl_gene_id: SCAB_24101
symbol: CBG69525.1
gene_biotype: protein_coding
description:
  Putative inositol monophosphatase; Function of phosphatidylinositol in mycobacteria: PMID: 15634688; Belongs to the inositol monophosphatase superfamily.


ensembl_gene_id: SCAB_24111
symbol: hemH
gene_biotype: protein_coding
description:
  Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.


ensembl_gene_id: SCAB_24421
symbol: CBG69554.1
gene_biotype: protein_coding
description:
  Putative transposase; PMID:16208464; cluster 0034: SCAB14601, SCAB16631, SCAB24421, SCAB30531, SCAB30841, SCAB68821, SCAB87301.


ensembl_gene_id: SCAB_24431
symbol: CBG69555.1
gene_biotype: protein_coding
description:
  Putative transposase; PMID:16208464; cluster 0034: SCAB14601, SCAB16631, SCAB24431, SCAB30531, SCAB30841, SCAB68821, SCAB87301; cluster 0050 6: SCAB16641, SCAB24431, SCAB30541, SCAB30831, SCAB68821, SCAB87291.


ensembl_gene_id: SCAB_24441
symbol: hrdB
gene_biotype: protein_coding
description:
  Major vegetative sigma factor HrdB; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.


ensembl_gene_id: SCAB_24631
symbol: nrdJ
gene_biotype: protein_coding
description:
  Vitamin B12-dependent ribonucleotide reductase; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.


ensembl_gene_id: SCAB_24641
symbol: nrdR
gene_biotype: protein_coding
description:
  Transcriptional repressor nrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.


ensembl_gene_id: SCAB_24651
symbol: lexA
gene_biotype: protein_coding
description:
  SOS repressor LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.


ensembl_gene_id: SCAB_24691
symbol: sidA
gene_biotype: protein_coding
description:
  Putative aminotransferase; PMID:11274118; possible NIS system; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: SCAB_24721
symbol: hflX
gene_biotype: protein_coding
description:
  Putative GTP-ase; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.


ensembl_gene_id: SCAB_24741
symbol: CBG69583.1
gene_biotype: protein_coding
description:
  Putative guanosine tetraphosphate (ppGpp) metabolism protein; Cluster 0567 with SCAB74961; possible NIS system.


ensembl_gene_id: SCAB_24751
symbol: dapF
gene_biotype: protein_coding
description:
  Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.


ensembl_gene_id: SCAB_24771
symbol: miaA
gene_biotype: protein_coding
description:
  Putative tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.


ensembl_gene_id: SCAB_24811
symbol: miaB
gene_biotype: protein_coding
description:
  Putative Radical SAM protein; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.


ensembl_gene_id: SCAB_24951
symbol: recA
gene_biotype: protein_coding
description:
  DNA recombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.


ensembl_gene_id: SCAB_25091
symbol: CBG69616.1
gene_biotype: protein_coding
description:
  Putative CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: SCAB_25101
symbol: rimO
gene_biotype: protein_coding
description:
  Putative radical SAM protein; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily.


ensembl_gene_id: SCAB_25141
symbol: CBG69621.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Strong matches to receiver domain of two component system response regulator, but no DNA binding domain; cluster 0571 with SCAB61481.


ensembl_gene_id: SCAB_25181
symbol: rnj
gene_biotype: protein_coding
description:
  Putative lactamase-b family hydrolase; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.


ensembl_gene_id: SCAB_25191
symbol: dapA1
gene_biotype: protein_coding
description:
  Putative dihydrodipicolinate synthase 1; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).


ensembl_gene_id: SCAB_25201
symbol: CBG69627.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.


ensembl_gene_id: SCAB_25231
symbol: dapB
gene_biotype: protein_coding
description:
  Putative dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.


ensembl_gene_id: SCAB_25251
symbol: gpsI
gene_biotype: protein_coding
description:
  Guanosine pentaphosphate synthetase/polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.


ensembl_gene_id: SCAB_25261
symbol: rpsO
gene_biotype: protein_coding
description:
  30S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.


ensembl_gene_id: SCAB_25321
symbol: truB
gene_biotype: protein_coding
description:
  Putative tRNA pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.


ensembl_gene_id: SCAB_25331
symbol: rbfA
gene_biotype: protein_coding
description:
  Putative ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.


ensembl_gene_id: SCAB_25351
symbol: infB
gene_biotype: protein_coding
description:
  Putative translation initiation/elongation factor; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.


ensembl_gene_id: SCAB_25371
symbol: nusA
gene_biotype: protein_coding
description:
  Putative transcriptional termination/antitermination factor; Participates in both transcription termination and antitermination.


ensembl_gene_id: SCAB_25381
symbol: rimP
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.


ensembl_gene_id: SCAB_25421
symbol: proS
gene_biotype: protein_coding
description:
  Prolyl tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...]


ensembl_gene_id: SCAB_25451
symbol: gcpE
gene_biotype: protein_coding
description:
  Putative GcpE2 (4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 2); Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family.


ensembl_gene_id: SCAB_25481
symbol: dxr
gene_biotype: protein_coding
description:
  1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family.


ensembl_gene_id: SCAB_25691
symbol: gabT
gene_biotype: protein_coding
description:
  Putative 4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: SCAB_25751
symbol: potA
gene_biotype: protein_coding
description:
  Putative polyamine ABC-transporter; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.


ensembl_gene_id: SCAB_25921
symbol: fbpC
gene_biotype: protein_coding
description:
  Putative ABC transporter; Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import. Responsible for energy coupling to the transport system.


ensembl_gene_id: SCAB_25951
symbol: rlmN
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family.


ensembl_gene_id: SCAB_25991
symbol: frr
gene_biotype: protein_coding
description:
  Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.


ensembl_gene_id: SCAB_26011
symbol: tsf
gene_biotype: protein_coding
description:
  Elongation factor TS; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.


ensembl_gene_id: SCAB_26051
symbol: whiG
gene_biotype: protein_coding
description:
  Sporulation-specific sigma factor WhiG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.


ensembl_gene_id: SCAB_26131
symbol: CBG69717.1
gene_biotype: protein_coding
description:
  Putative signal peptidase; PMID: 10520735; cluster 0579 with SCAB26121; Belongs to the peptidase S26 family.


ensembl_gene_id: SCAB_26151
symbol: rplS
gene_biotype: protein_coding
description:
  50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.


ensembl_gene_id: SCAB_26161
symbol: trmD
gene_biotype: protein_coding
description:
  tRNA (guanine-N1)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.


ensembl_gene_id: SCAB_26171
symbol: rimM
gene_biotype: protein_coding
description:
  Putative 16S rRNA processing protein; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family.


ensembl_gene_id: SCAB_26211
symbol: proS-2
gene_biotype: protein_coding
description:
  Putative class II tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).


ensembl_gene_id: SCAB_26231
symbol: ffh
gene_biotype: protein_coding
description:
  Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.


ensembl_gene_id: SCAB_26241
symbol: glnD
gene_biotype: protein_coding
description:
  Putative protein P-II uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.


ensembl_gene_id: SCAB_26291
symbol: ftsY
gene_biotype: protein_coding
description:
  Putative signal recognition particle receptor; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).


ensembl_gene_id: SCAB_26321
symbol: glcP
gene_biotype: protein_coding
description:
  Glucose transport protein GlcP; PMID: 15659175; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.


ensembl_gene_id: SCAB_26331
symbol: smc
gene_biotype: protein_coding
description:
  Putative chromosome associated protein; Required for chromosome condensation and partitioning. Belongs to the SMC family.


ensembl_gene_id: SCAB_26381
symbol: fpg
gene_biotype: protein_coding
description:
  Putative formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.


ensembl_gene_id: SCAB_26391
symbol: rnc
gene_biotype: protein_coding
description:
  Putative ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.


ensembl_gene_id: SCAB_26421
symbol: coaD
gene_biotype: protein_coding
description:
  Putative phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.


ensembl_gene_id: SCAB_26441
symbol: recG
gene_biotype: protein_coding
description:
  Putative ATP-dependent DNA helicase; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily.


ensembl_gene_id: SCAB_26501
symbol: thiL
gene_biotype: protein_coding
description:
  Putative thiamine monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.


ensembl_gene_id: SCAB_26541
symbol: gpdA
gene_biotype: protein_coding
description:
  Glycerol-3-phosphate dehydrogenase; Cluster 0583 with SCAB79801; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.


ensembl_gene_id: SCAB_26561
symbol: fbiD
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.


ensembl_gene_id: SCAB_26581
symbol: CBG69762.1
gene_biotype: protein_coding
description:
  Putative histone-like DNA binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.


ensembl_gene_id: SCAB_26601
symbol: leuD
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.


ensembl_gene_id: SCAB_26611
symbol: leuC
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.


ensembl_gene_id: SCAB_26661
symbol: gltX
gene_biotype: protein_coding
description:
  glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).


ensembl_gene_id: SCAB_26951
symbol: leuB
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.


ensembl_gene_id: SCAB_27051
symbol: serA
gene_biotype: protein_coding
description:
  Putative D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: SCAB_27061
symbol: ilvC
gene_biotype: protein_coding
description:
  Acetolactate synthase small subunit; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.


ensembl_gene_id: SCAB_27201
symbol: gatB
gene_biotype: protein_coding
description:
  Putative glutamyl tRNA(Gln) amidotransferase subunit B; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily.


ensembl_gene_id: SCAB_2721
symbol: SCAB_2721
gene_biotype: protein_coding
description:
  Putative transport-related, membrane protein; Belongs to the purine-cytosine permease (2.A.39) family.


ensembl_gene_id: SCAB_27221
symbol: gatA
gene_biotype: protein_coding
description:
  Putative glutamyl tRNA(Gln) amidotransferase subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln).


ensembl_gene_id: SCAB_27231
symbol: gatC
gene_biotype: protein_coding
description:
  Putative Glu-tRNA(Gln) amidotransferase subunit C; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family.


ensembl_gene_id: SCAB_27251
symbol: ligA
gene_biotype: protein_coding
description:
  Putative DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.


ensembl_gene_id: SCAB_27301
symbol: trmU
gene_biotype: protein_coding
description:
  Putative tRNA (5-methylaminomethyl-2-thiouridylate) methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.


ensembl_gene_id: SCAB_27461
symbol: gcvT
gene_biotype: protein_coding
description:
  Putative glycine cleavage T protein aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine.


ensembl_gene_id: SCAB_27481
symbol: gcvH
gene_biotype: protein_coding
description:
  Putative glycine cleavage H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.


ensembl_gene_id: SCAB_27491
symbol: glyA2
gene_biotype: protein_coding
description:
  Putative serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.


ensembl_gene_id: SCAB_27531
symbol: CBG69855.1
gene_biotype: protein_coding
description:
  Putative transcriptional regulatory protein; PMID: 15563836; PMID: 10873841; PMID: 15328113; TTA-Leu codon(s) 214 may indicate regulation by BldA.


ensembl_gene_id: SCAB_27651
symbol: CBG69866.1
gene_biotype: protein_coding
description:
  Hypothetical protein; High GC compared to background. Bias in amino acids towards Ala, Pro, fastA hits primarily from hydrophilic composition.


ensembl_gene_id: SCAB_27801
symbol: CBG69881.1
gene_biotype: protein_coding
description:
  Putative enoyl-coA hydratase/isomerase family protein; Belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: SCAB_27981
symbol: pep1A
gene_biotype: protein_coding
description:
  Putative alpha-amylase; Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.


ensembl_gene_id: SCAB_27991
symbol: treSA
gene_biotype: protein_coding
description:
  Putative alpha amylase; PMID: 10821190; PMID:10821190 in S. coelicolor, clusters of pep1-treS-pep2-glgB genes; glgB involved in aerial mycelium development.


ensembl_gene_id: SCAB_28001
symbol: pep2A
gene_biotype: protein_coding
description:
  Conserved hypothetical Pep2A protein; PMID:10821190; PMID:15378530; cluster 0601 with SCAB83371; PMID:10821190 in S. coelicolor, clusters of pep1-treS-pep2-glgB genes; glgB involved in aerial mycelium development.


ensembl_gene_id: SCAB_28011
symbol: glgB1
gene_biotype: protein_coding
description:
  Putative 1,4-a-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.


ensembl_gene_id: SCAB_28061
symbol: CBG69906.1
gene_biotype: protein_coding
description:
  Putative sodium:dicarboxylate symporter; Cluster 0604 with SCAB80081; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: SCAB_28121
symbol: CBG69911.1
gene_biotype: protein_coding
description:
  Putative AfsR-like regulator; PMID: 10517581; PMID: 15921897; cluster 0230 with SCAB28161 and SCAB28181.


ensembl_gene_id: SCAB_28161
symbol: CBG69915.1
gene_biotype: protein_coding
description:
  Putative AfsR-like regulator; PMID: 10517581; PMID: 15921897; cluster 0230 with SCAB28121 and SCAB28181.


ensembl_gene_id: SCAB_28171
symbol: CBG69916.1
gene_biotype: protein_coding
description:
  Putative phosphorylase; Cluster 0605 with SCAB28111; TTA-Leu codon(s) 258 may indicate regulation by BldA.


ensembl_gene_id: SCAB_28181
symbol: CBG69917.1
gene_biotype: protein_coding
description:
  Putative AfsR-like regulator; PMID: 15921897; cluster 0230 with SCAB28121 and SCAB28161; TTA-Leu codon(s) 179 may indicate regulation by BldA.


ensembl_gene_id: SCAB_28201
symbol: pfkA2
gene_biotype: protein_coding
description:
  6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.


ensembl_gene_id: SCAB_28221
symbol: pta
gene_biotype: protein_coding
description:
  Putative phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.


ensembl_gene_id: SCAB_28231
symbol: ackA
gene_biotype: protein_coding
description:
  Putative acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.


ensembl_gene_id: SCAB_28481
symbol: fadA
gene_biotype: protein_coding
description:
  Putative acetyl-coA C-acetyltransferase FadA; PMID:11518326; Belongs to the thiolase-like superfamily. Thiolase family.


ensembl_gene_id: SCAB_28601
symbol: nucS
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Cleaves both 3' and 5' ssDNA extremities of branched DNA structures; Belongs to the NucS endonuclease family.


ensembl_gene_id: SCAB_28681
symbol: CBG69967.1
gene_biotype: protein_coding
description:
  Putative cobalamin adenosyltransferase; PMID: 14734568; Belongs to the Cob(I)alamin adenosyltransferase family.


ensembl_gene_id: SCAB_28751
symbol: atpC
gene_biotype: protein_coding
description:
  ATP synthase epsilon chain; Produces ATP from ADP in the presence of a proton gradient across the membrane.


ensembl_gene_id: SCAB_28761
symbol: atpD
gene_biotype: protein_coding
description:
  ATP synthase beta chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family.


ensembl_gene_id: SCAB_28771
symbol: atpG
gene_biotype: protein_coding
description:
  ATP synthase gamma chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.


ensembl_gene_id: SCAB_28781
symbol: atpA
gene_biotype: protein_coding
description:
  ATP synthase alpha chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family.


ensembl_gene_id: SCAB_28791
symbol: atpH
gene_biotype: protein_coding
description:
  ATP synthase delta chain; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family.


ensembl_gene_id: SCAB_28801
symbol: atpF
gene_biotype: protein_coding
description:
  ATP synthase B chain; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family.


ensembl_gene_id: SCAB_28811
symbol: atpE
gene_biotype: protein_coding
description:
  ATP synthase C chain; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.


ensembl_gene_id: SCAB_28821
symbol: atpB
gene_biotype: protein_coding
description:
  ATP synthase A chain; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.


ensembl_gene_id: SCAB_28861
symbol: CBG69985.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.


ensembl_gene_id: SCAB_28881
symbol: prmC
gene_biotype: protein_coding
description:
  Putative methylase; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.


ensembl_gene_id: SCAB_28891
symbol: prfA
gene_biotype: protein_coding
description:
  Peptide chain release factor 1 (RF-1); Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.


ensembl_gene_id: SCAB_28931
symbol: rho
gene_biotype: protein_coding
description:
  Transcription terminator factor (fragment); Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.


ensembl_gene_id: SCAB_28941
symbol: thrB
gene_biotype: protein_coding
description:
  Putative homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.


ensembl_gene_id: SCAB_28951
symbol: thrC
gene_biotype: protein_coding
description:
  Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.


ensembl_gene_id: SCAB_28971
symbol: lysA
gene_biotype: protein_coding
description:
  Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.


ensembl_gene_id: SCAB_29211
symbol: CBG70023.1
gene_biotype: protein_coding
description:
  Putative type I restriction enzyme; Subunit R is required for both nuclease and ATPase activities, but not for modification.


ensembl_gene_id: SCAB_29491
symbol: ku
gene_biotype: protein_coding
description:
  Putative DNA-binding protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.


ensembl_gene_id: SCAB_29731
symbol: lon
gene_biotype: protein_coding
description:
  Putative ATP-dependent protease; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.


ensembl_gene_id: SCAB_29881
symbol: atrA
gene_biotype: protein_coding
description:
  Putative extracellular binding protein; PMID: 9466266; Belongs to the bacterial solute-binding protein 3 family.


ensembl_gene_id: SCAB_30071
symbol: CBG70112.1
gene_biotype: protein_coding
description:
  Putative Na+/H+ antiporter; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.


ensembl_gene_id: SCAB_30131
symbol: wblE
gene_biotype: protein_coding
description:
  Hypothetical protein; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.


ensembl_gene_id: SCAB_30151
symbol: nagB
gene_biotype: protein_coding
description:
  Putative glucosamine phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion; Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.


ensembl_gene_id: SCAB_30261
symbol: nrdL
gene_biotype: protein_coding
description:
  Ribonucleotide-diphosphate reductase large chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.


ensembl_gene_id: SCAB_30271
symbol: nrdM
gene_biotype: protein_coding
description:
  Ribonucleotide-diphosphate reductase small chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.


ensembl_gene_id: SCAB_30301
symbol: def
gene_biotype: protein_coding
description:
  Putative polypeptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.


ensembl_gene_id: SCAB_30381
symbol: sigR
gene_biotype: protein_coding
description:
  Putative oxidative stress sigma factor; PMID: 10428967; PMID: 9755177; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: SCAB_30421
symbol: aroA2
gene_biotype: protein_coding
description:
  3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.


ensembl_gene_id: SCAB_30431
symbol: rsgA-2
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.


ensembl_gene_id: SCAB_30531
symbol: CBG70158.1
gene_biotype: protein_coding
description:
  Putative transposase; PMID: 16208464; cluster 0034: SCAB14601, SCAB16631, SCAB24421, SCAB30531, SCAB30841, SCAB68821, SCAB87301.


ensembl_gene_id: SCAB_30541
symbol: CBG70159.1
gene_biotype: protein_coding
description:
  Putative insertion element transposase; PMID: 16208464; cluster 0050 6: SCAB16641, SCAB24431, SCAB30541, SCAB30831, SCAB68821, SCAB87291.


ensembl_gene_id: SCAB_30701
symbol: whiB-5
gene_biotype: protein_coding
description:
  Putative DNA-binding protein; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.


ensembl_gene_id: SCAB_31101
symbol: CBG70212.1
gene_biotype: protein_coding
description:
  Putative ATP-binding protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.


ensembl_gene_id: SCAB_31211
symbol: folP
gene_biotype: protein_coding
description:
  Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.


ensembl_gene_id: SCAB_31271
symbol: fdxA1
gene_biotype: protein_coding
description:
  Ferredoxin; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.


ensembl_gene_id: SCAB_31361
symbol: mshB
gene_biotype: protein_coding
description:
  Putative N-acetylglucosaminylphosphatidylinositol de-N-acetylase; Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2- deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.


ensembl_gene_id: SCAB_31511
symbol: bldKD
gene_biotype: protein_coding
description:
  BldKD putative oligopeptide ABC transporter subunit; PMID: 8971710; PMID: 16006069; Belongs to the ABC transporter superfamily.


ensembl_gene_id: SCAB_31531
symbol: bldKB
gene_biotype: protein_coding
description:
  Putative BldKB-like transport system extracellular solute-binding protein; PMID: 8971710; PMID: 16006069.


ensembl_gene_id: SCAB_31761
symbol: txtC
gene_biotype: protein_coding
description:
  Putative monooxygenase; PMID: 11889110; PMID: 15686551; PMID: 11988517; thaxtomin synthesis monooxygenase probably involved in pathogenicity; Belongs to the cytochrome P450 family.


ensembl_gene_id: SCAB_31781
symbol: txtB
gene_biotype: protein_coding
description:
  Thaxtomin synthetase B; PMID: 11115114; PMID: 15686551; PMID: 10780924; thaxtomin synthesis - pathogenicity associated.


ensembl_gene_id: SCAB_31801
symbol: txtR
gene_biotype: protein_coding
description:
  Cellobiose-dependent regulator TxtR; PMID: 15686551; PMID:11004184; PMID:8631685; PMID: 17919290; no significant Pfam domain matches; strong match to S. turgidiscabies pathogenicity island; TTA-Leu codon(s) 203 may indicate regulation by BldA.


ensembl_gene_id: SCAB_31831
symbol: CBG70284.1
gene_biotype: protein_coding
description:
  Putative P450-like protein; PMID: 15686551; strong match to S. turgidiscabies pathogenicity island; Belongs to the cytochrome P450 family.


ensembl_gene_id: SCAB_31841
symbol: txtD
gene_biotype: protein_coding
description:
  Putative oxygenase; Catalyzes the production of nitric oxide. Belongs to the NOS family. Bacterial NOS oxygenase subfamily.


ensembl_gene_id: SCAB_31971
symbol: CBG70297.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Lantibiotics biosynthesis; TTA-Leu codon(s) 53 may indicate regulation by BldA.


ensembl_gene_id: SCAB_3201
symbol: SCAB_3201
gene_biotype: protein_coding
description:
  Putative secreted protein; Contains PF01839 FG-GAP repeats see also SCAB1291, SCAB58141; TTA-Leu codon(s) 19 may indicate regulation by BldA.


ensembl_gene_id: SCAB_32041
symbol: CBG70306.1
gene_biotype: protein_coding
description:
  Putative lanthionine synthetase C-like protein; Lantibiotics biosynthesis; TTA-Leu codon(s) 221 may indicate regulation by BldA.


ensembl_gene_id: SCAB_3211
symbol: SCAB_3211
gene_biotype: protein_coding
description:
  GdmH-like proteins also catch PF02698 (DUF218): in ABC transporters secreting antimicrobial peptides c.f. PMID: 11229936.


ensembl_gene_id: SCAB_32111
symbol: rarD2
gene_biotype: protein_coding
description:
  RarD (conservon) homologue; PMID: 12657469; conservon; TTA-Leu codon(s) 129 may indicate regulation by BldA.


ensembl_gene_id: SCAB_32131
symbol: CBG70315.1
gene_biotype: protein_coding
description:
  Putative monooxygenase; PMID: 12791134; PMID: 10467127; PMID: 15111132; Belongs to the cytochrome P450 family.


ensembl_gene_id: SCAB_3221
symbol: SCAB_3221
gene_biotype: protein_coding
description:
  NRPS multienzyme (AMP-binding and pcp); PMID:15112993; Belongs to the ATP-dependent AMP-binding enzyme family.


ensembl_gene_id: SCAB_32271
symbol: CBG70328.1
gene_biotype: protein_coding
description:
  Putative membrane protein; PMID:12591872; PMID:2836730; cluster 0500 with SCAB21751; similarity could be from low complexity? mask and retry. Contains repeat region codons 400-460.


ensembl_gene_id: SCAB_32392
symbol: CBG70341.1
gene_biotype: protein_coding
description:
  Hypothetical protein; No significant db matches; TTA-Leu codon(s) 185 may indicate regulation by BldA.


ensembl_gene_id: SCAB_3241
symbol: SCAB_3241
gene_biotype: protein_coding
description:
  Putative thioesterase; PMID:15112993; PMID:10473585; many matches in secondary metabolite biosynthesis.


ensembl_gene_id: SCAB_32581
symbol: SCAB_32581
gene_biotype: protein_coding
description:
  Conserved hypothetical protein (fragment); HMMPfam hit to PF03771, Domain of unknown function (DUF317), score 1.7e-15.


ensembl_gene_id: SCAB_32621
symbol: CBG70362.1
gene_biotype: protein_coding
description:
  Putative ATP-binding biosynthetic enzyme; PMID: 14693539; cluster 0166 with SCAB22041 and SCAB11921.


ensembl_gene_id: SCAB_32751
symbol: CBG70375.1
gene_biotype: protein_coding
description:
  Putative DNA methylase; Cluster 0522 with SCAB22171; Belongs to the N(4)/N(6)-methyltransferase family.


ensembl_gene_id: SCAB_3291
symbol: SCAB_3291
gene_biotype: protein_coding
description:
  Putative oxidoreductase; Cluster 0135 collects two pairs: SCAB3291 and SCAB3301, SCAB62911 and SCAB62921.


ensembl_gene_id: SCAB_32941
symbol: CBG70393.1
gene_biotype: protein_coding
description:
  Putative glycosyl transferase; PMID:16024079; cluster 0529 with SCAB22311 which has Pfam match PF00535 glycosyl transferase; TTA-Leu codon(s) 177 may indicate regulation by BldA.


ensembl_gene_id: SCAB_33161
symbol: CBG70414.1
gene_biotype: protein_coding
description:
  Putative membrane protein; Cluster 0541 with SCAB22481; TTA-Leu codon(s) 589 may indicate regulation by BldA.


ensembl_gene_id: SCAB_33201
symbol: CBG70418.1
gene_biotype: protein_coding
description:
  Putative restriction/modification system DNA methylase; PMID:16368872; cluster 0544 with SCAB22551; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.


ensembl_gene_id: SCAB_3321
symbol: SCAB_3321
gene_biotype: protein_coding
description:
  Putative non-ribosomal peptide synthetase; PMID:10801488; PMID:9006024; PMID:16647040; PMID:9427658.


ensembl_gene_id: SCAB_33271
symbol: CBG70424.1
gene_biotype: protein_coding
description:
  Putative transposase; PMID: 10658661; PMID: 1700062; PMID: 10217489; see also SCAB14321, SCAB21921, SCAB77071; 50% identity to transposases on S. turgidiscabies PAI.


ensembl_gene_id: SCAB_33441
symbol: aviX1
gene_biotype: protein_coding
description:
  Putative ATP/GTP binding protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.


ensembl_gene_id: SCAB_33471
symbol: ispH
gene_biotype: protein_coding
description:
  Putative 4-hydroxy-3-methylbut-2-enyl diphosphate reductase IspH; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.


ensembl_gene_id: SCAB_33481
symbol: xseA
gene_biotype: protein_coding
description:
  Putative exonuclease VII large subunit XseA; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family.


ensembl_gene_id: SCAB_33491
symbol: xseB
gene_biotype: protein_coding
description:
  Putative exonuclease small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.


ensembl_gene_id: SCAB_3351
symbol: SCAB_3351
gene_biotype: protein_coding
description:
  Putative aminotransferase; TTA-Leu codon(s) 8 may indicate regulation by BldA; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: SCAB_33531
symbol: wblI
gene_biotype: protein_coding
description:
  Conserved hypothetical protein WblI; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.


ensembl_gene_id: SCAB_33551
symbol: fumB
gene_biotype: protein_coding
description:
  Fumarate hydratase class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.


ensembl_gene_id: SCAB_33571
symbol: fumC
gene_biotype: protein_coding
description:
  Fumarate hydratase C; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.


ensembl_gene_id: SCAB_3361
symbol: SCAB_3361
gene_biotype: protein_coding
description:
  Putative NT-sugar reductase; PMID:16723573; PMID:15112997; PMID:9353926; PMID:10972798; PMID:10767533.


ensembl_gene_id: SCAB_33641
symbol: ahpD
gene_biotype: protein_coding
description:
  Alkyl hydroperoxide reductase system hypothetical protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.


ensembl_gene_id: SCAB_33671
symbol: uppS1
gene_biotype: protein_coding
description:
  Putative undecaprenyl pyrophosphate synthetase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.


ensembl_gene_id: SCAB_34111
symbol: pckG
gene_biotype: protein_coding
description:
  Putative phosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.


ensembl_gene_id: SCAB_34301
symbol: mca
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S- conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics; Belongs to the MshB deacetylase family. Mca subfamily.


ensembl_gene_id: SCAB_3431
symbol: adk-2
gene_biotype: protein_coding
description:
  Putative adenylate kinase (fragment); Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.


ensembl_gene_id: SCAB_34321
symbol: greA
gene_biotype: protein_coding
description:
  Putative transcription elongation factor; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.


ensembl_gene_id: SCAB_34411
symbol: msrA
gene_biotype: protein_coding
description:
  Putative methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.


ensembl_gene_id: SCAB_34601
symbol: CBG70554.1
gene_biotype: protein_coding
description:
  Putative Maf-like protein protein; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.


ensembl_gene_id: SCAB_34681
symbol: CBG70562.1
gene_biotype: protein_coding
description:
  Putative phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.


ensembl_gene_id: SCAB_34741
symbol: CBG70566.1
gene_biotype: protein_coding
description:
  Putative deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate.


ensembl_gene_id: SCAB_34861
symbol: add-2
gene_biotype: protein_coding
description:
  Putative adenosine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.


ensembl_gene_id: SCAB_34941
symbol: CBG70585.1
gene_biotype: protein_coding
description:
  Putative sugar ABC transporter; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: SCAB_35111
symbol: CBG70602.1
gene_biotype: protein_coding
description:
  Putative transposase; Cluster 0138: SCAB35111, SCAB57961, SCAB59871, SCAB87221; no Pfam: evidence for transposition inferred from 4 exact duplicates in genome; TTA-Leu codon(s) 3, 26 may indicate regulation by BldA.


ensembl_gene_id: SCAB_35301
symbol: dhsB
gene_biotype: protein_coding
description:
  Putative succinate dehydrogenase iron-sulfur subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.


ensembl_gene_id: SCAB_35601
symbol: trpS2
gene_biotype: protein_coding
description:
  tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: SCAB_35641
symbol: glyA1
gene_biotype: protein_coding
description:
  Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.


ensembl_gene_id: SCAB_35681
symbol: mdh
gene_biotype: protein_coding
description:
  Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.


ensembl_gene_id: SCAB_35711
symbol: folD
gene_biotype: protein_coding
description:
  Methylenetetrahydrofolatedehydrogenase/cyclohyd ro lase); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.


ensembl_gene_id: SCAB_35751
symbol: purN
gene_biotype: protein_coding
description:
  Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.


ensembl_gene_id: SCAB_35791
symbol: sucD
gene_biotype: protein_coding
description:
  succinyl-CoA synthetase alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.


ensembl_gene_id: SCAB_35801
symbol: sucC
gene_biotype: protein_coding
description:
  succinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.


ensembl_gene_id: SCAB_36181
symbol: CBG70707.1
gene_biotype: protein_coding
description:
  Putative glycerol phosphate dehydrogenase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.


ensembl_gene_id: SCAB_36191
symbol: CBG70708.1
gene_biotype: protein_coding
description:
  Putative nucleotide-sugar dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.


ensembl_gene_id: SCAB_36211
symbol: guaB
gene_biotype: protein_coding
description:
  IMP dehydrogenase/ GMP reductase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.


ensembl_gene_id: SCAB_36241
symbol: whiD
gene_biotype: protein_coding
description:
  Putative WhiB family regulatory protein; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.


ensembl_gene_id: SCAB_36291
symbol: groL1
gene_biotype: protein_coding
description:
  60 kD chaperonin cpn60; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.


ensembl_gene_id: SCAB_36301
symbol: groS
gene_biotype: protein_coding
description:
  10 kD chaperonin cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.


ensembl_gene_id: SCAB_36461
symbol: gcp
gene_biotype: protein_coding
description:
  Putative O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.


ensembl_gene_id: SCAB_36531
symbol: alr
gene_biotype: protein_coding
description:
  Putative alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.


ensembl_gene_id: SCAB_36551
symbol: glmS
gene_biotype: protein_coding
description:
  Glucosamine--fructose-6-phosphateaminotransfera se; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.


ensembl_gene_id: SCAB_36561
symbol: acpS
gene_biotype: protein_coding
description:
  Putative holo-ACP synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.


ensembl_gene_id: SCAB_36571
symbol: nnrD
gene_biotype: protein_coding
description:
  Putative carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.  Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of  [...]


ensembl_gene_id: SCAB_36611
symbol: glmM
gene_biotype: protein_coding
description:
  Putative phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.


ensembl_gene_id: SCAB_36631
symbol: rplM
gene_biotype: protein_coding
description:
  50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.


ensembl_gene_id: SCAB_36651
symbol: truA
gene_biotype: protein_coding
description:
  Putative tRNA-pseudouridine synthase; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.


ensembl_gene_id: SCAB_36671
symbol: rpoA
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: SCAB_36681
symbol: rpsK
gene_biotype: protein_coding
description:
  30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.


ensembl_gene_id: SCAB_36691
symbol: rpsM
gene_biotype: protein_coding
description:
  30S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family.


ensembl_gene_id: SCAB_36711
symbol: infA
gene_biotype: protein_coding
description:
  Translational initiation factor IF1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.


ensembl_gene_id: SCAB_36721
symbol: map
gene_biotype: protein_coding
description:
  Methionyl aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.


ensembl_gene_id: SCAB_36731
symbol: adk
gene_biotype: protein_coding
description:
  Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.


ensembl_gene_id: SCAB_36741
symbol: secY
gene_biotype: protein_coding
description:
  Preprotein translocase SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.


ensembl_gene_id: SCAB_36751
symbol: rplO
gene_biotype: protein_coding
description:
  50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.


ensembl_gene_id: SCAB_36771
symbol: rpsE
gene_biotype: protein_coding
description:
  30S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.


ensembl_gene_id: SCAB_36781
symbol: rplR
gene_biotype: protein_coding
description:
  50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.


ensembl_gene_id: SCAB_36791
symbol: rplF
gene_biotype: protein_coding
description:
  50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.


ensembl_gene_id: SCAB_36801
symbol: rpsH
gene_biotype: protein_coding
description:
  30S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.


ensembl_gene_id: SCAB_36811
symbol: rpsN
gene_biotype: protein_coding
description:
  30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.


ensembl_gene_id: SCAB_36821
symbol: rplE
gene_biotype: protein_coding
description:
  50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.


ensembl_gene_id: SCAB_36831
symbol: rplX
gene_biotype: protein_coding
description:
  50S ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.


ensembl_gene_id: SCAB_36841
symbol: rplN
gene_biotype: protein_coding
description:
  50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.


ensembl_gene_id: SCAB_36851
symbol: rpsQ
gene_biotype: protein_coding
description:
  30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.


ensembl_gene_id: SCAB_36871
symbol: rplP
gene_biotype: protein_coding
description:
  50S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.


ensembl_gene_id: SCAB_36881
symbol: rpsC
gene_biotype: protein_coding
description:
  30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.


ensembl_gene_id: SCAB_36891
symbol: rplV
gene_biotype: protein_coding
description:
  50S ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.


ensembl_gene_id: SCAB_36901
symbol: rpsS
gene_biotype: protein_coding
description:
  30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.


ensembl_gene_id: SCAB_36911
symbol: rplB
gene_biotype: protein_coding
description:
  50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.


ensembl_gene_id: SCAB_36921
symbol: rplW
gene_biotype: protein_coding
description:
  50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.


ensembl_gene_id: SCAB_36941
symbol: rplC
gene_biotype: protein_coding
description:
  50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.


ensembl_gene_id: SCAB_36951
symbol: rpsJ
gene_biotype: protein_coding
description:
  30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.


ensembl_gene_id: SCAB_37091
symbol: tuf1
gene_biotype: protein_coding
description:
  Elongation factor TU-1; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.


ensembl_gene_id: SCAB_37111
symbol: rspG
gene_biotype: protein_coding
description:
  30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.


ensembl_gene_id: SCAB_37121
symbol: rpsL
gene_biotype: protein_coding
description:
  Putative 30S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.


ensembl_gene_id: SCAB_37181
symbol: rpoC
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase beta' chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: SCAB_37191
symbol: rpoB
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: SCAB_37201
symbol: rplL
gene_biotype: protein_coding
description:
  50S ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family.


ensembl_gene_id: SCAB_37211
symbol: rplJ
gene_biotype: protein_coding
description:
  50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.


ensembl_gene_id: SCAB_37231
symbol: rlpA
gene_biotype: protein_coding
description:
  50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.


ensembl_gene_id: SCAB_37241
symbol: rplK
gene_biotype: protein_coding
description:
  50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.


ensembl_gene_id: SCAB_37251
symbol: nusG
gene_biotype: protein_coding
description:
  Transcription antitermination protein; Participates in transcription elongation, termination and antitermination.


ensembl_gene_id: SCAB_37261
symbol: secE
gene_biotype: protein_coding
description:
  Preprotein translocase SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.


ensembl_gene_id: SCAB_37421
symbol: nuoN2
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit NuoN2; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family.


ensembl_gene_id: SCAB_37451
symbol: nuoK2
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit NuoK2; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family.


ensembl_gene_id: SCAB_37461
symbol: nuoJ2
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit NuoJ2; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: SCAB_37471
symbol: nuoI2
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit NuoI2; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: SCAB_37481
symbol: nuoH2
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit NuoH2; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.


ensembl_gene_id: SCAB_37501
symbol: nuoB2
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit NuoB2; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: SCAB_37511
symbol: nuoA2
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit NuoA2; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.


ensembl_gene_id: SCAB_37961
symbol: nuoN
gene_biotype: protein_coding
description:
  NuoN, NADH dehydrogenase subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family.


ensembl_gene_id: SCAB_37991
symbol: nuoK
gene_biotype: protein_coding
description:
  NuoK, NADH dehydrogenase subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family.


ensembl_gene_id: SCAB_38001
symbol: nuoJ
gene_biotype: protein_coding
description:
  NuoJ, NADH dehydrogenase subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: SCAB_38011
symbol: nuoI
gene_biotype: protein_coding
description:
  NuoI, NADH dehydrogenase subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: SCAB_38021
symbol: nuoH
gene_biotype: protein_coding
description:
  NuoH, NADH dehydrogenase subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.


ensembl_gene_id: SCAB_38031
symbol: nuoG
gene_biotype: protein_coding
description:
  NuoG, NADH dehydrogenase subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family.


ensembl_gene_id: SCAB_38041
symbol: nuoF
gene_biotype: protein_coding
description:
  NuoF, NADH dehydrogenase subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family.


ensembl_gene_id: SCAB_38061
symbol: nuoD
gene_biotype: protein_coding
description:
  NuoD, NADH dehydrogenase subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family.


ensembl_gene_id: SCAB_38071
symbol: nuoC
gene_biotype: protein_coding
description:
  NuoC, NADH dehydrogenase subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 30 kDa subunit family.


ensembl_gene_id: SCAB_38081
symbol: nuoB
gene_biotype: protein_coding
description:
  NuoB, NADH dehydrogenase subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: SCAB_38091
symbol: nuoA
gene_biotype: protein_coding
description:
  NuoA, NADH dehydrogenase subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family.


ensembl_gene_id: SCAB_38161
symbol: menG
gene_biotype: protein_coding
description:
  Putative methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).


ensembl_gene_id: SCAB_38191
symbol: mqnC
gene_biotype: protein_coding
description:
  Putative radical SAM superfamily protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).


ensembl_gene_id: SCAB_38221
symbol: mqnA
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).


ensembl_gene_id: SCAB_38341
symbol: mqnE
gene_biotype: protein_coding
description:
  Putative radical SAM superfamily protein; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.


ensembl_gene_id: SCAB_38361
symbol: ubiX
gene_biotype: protein_coding
description:
  Putative flavoprotein; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family.


ensembl_gene_id: SCAB_38531
symbol: CBG70934.1
gene_biotype: protein_coding
description:
  Putative iron/ascorbate oxidoreductase family protein; Belongs to the iron/ascorbate-dependent oxidoreductase family.


ensembl_gene_id: SCAB_39071
symbol: hemC1
gene_biotype: protein_coding
description:
  Putative hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.


ensembl_gene_id: SCAB_39081
symbol: hemA
gene_biotype: protein_coding
description:
  Putative glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).


ensembl_gene_id: SCAB_39091
symbol: rex
gene_biotype: protein_coding
description:
  Redox-sensing transcriptional repressor rex; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.


ensembl_gene_id: SCAB_39121
symbol: CBG70992.1
gene_biotype: protein_coding
description:
  AdsA-like sigma factor; PMID:10913094; AdsA is regulated by AdpA in the A factor cascade in S. griseus; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: SCAB_39211
symbol: trpS2-2
gene_biotype: protein_coding
description:
  Putative tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: SCAB_39221
symbol: proC
gene_biotype: protein_coding
description:
  Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.


ensembl_gene_id: SCAB_39361
symbol: radA
gene_biotype: protein_coding
description:
  Putative DNA repair protein; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.


ensembl_gene_id: SCAB_39371
symbol: disA
gene_biotype: protein_coding
description:
  Putative DNA-binding protein; Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis.


ensembl_gene_id: SCAB_39411
symbol: sigE
gene_biotype: protein_coding
description:
  SigE-like sigma factor; PMID:11342219; PMID: 9004230; S1 and characterisation, PMID:11342219; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: SCAB_39441
symbol: cseC
gene_biotype: protein_coding
description:
  Putative two-component system sensor kinase; PMID: 10411727; PMID: 15561847; cluster 0614 with SCAB29561.


ensembl_gene_id: SCAB_39451
symbol: CBG71025.1
gene_biotype: protein_coding
description:
  Putative major facilitator exporter; PMID:10658661; PMID: 9933932; PMID:15313224; Belongs to the major facilitator superfamily.


ensembl_gene_id: SCAB_39561
symbol: coaX
gene_biotype: protein_coding
description:
  Putative transcriptional activator; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.


ensembl_gene_id: SCAB_39591
symbol: panC
gene_biotype: protein_coding
description:
  Putative pantoate-amino acid ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.


ensembl_gene_id: SCAB_39661
symbol: nuoD-2
gene_biotype: protein_coding
description:
  Putative electron transport protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family.


ensembl_gene_id: SCAB_39721
symbol: folP2
gene_biotype: protein_coding
description:
  Putative dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.


ensembl_gene_id: SCAB_39741
symbol: folB
gene_biotype: protein_coding
description:
  Putative dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.


ensembl_gene_id: SCAB_39781
symbol: ftsH
gene_biotype: protein_coding
description:
  Putative membrane-bound FtsH-family protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family.  In the central section; belongs to the AAA ATPase family.


ensembl_gene_id: SCAB_39791
symbol: hprT
gene_biotype: protein_coding
description:
  Putative hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.


ensembl_gene_id: SCAB_39801
symbol: tilS
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.


ensembl_gene_id: SCAB_39831
symbol: ppa
gene_biotype: protein_coding
description:
  Putative diphosphate phosphohydrolase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.


ensembl_gene_id: SCAB_39891
symbol: CBG71068.1
gene_biotype: protein_coding
description:
  Putative ABC transporter transmembrane subunit; TTA-Leu codon(s) 150 may indicate regulation by BldA.


ensembl_gene_id: SCAB_39971
symbol: rpsR
gene_biotype: protein_coding
description:
  Putative 30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.


ensembl_gene_id: SCAB_40021
symbol: rpsN-2
gene_biotype: protein_coding
description:
  Putative 30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family.


ensembl_gene_id: SCAB_40191
symbol: SCAB_40191
gene_biotype: protein_coding
description:
  Putative ABC transporter integral membrane subunit; HMMPfam hit to PF02687, Predicted permease, score 3.4e-13.


ensembl_gene_id: SCAB_40211
symbol: SCAB_40211
gene_biotype: protein_coding
description:
  Putative two-component system sensor kinase; 4 probable transmembrane helices predicted for SCAB40201 by TMHMM2.0 at aa 22-41, 48-70, 85-107 and 120-142.


ensembl_gene_id: SCAB_40681
symbol: vapC
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family.


ensembl_gene_id: SCAB_40761
symbol: tmk
gene_biotype: protein_coding
description:
  Putative thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.


ensembl_gene_id: SCAB_40781
symbol: topA
gene_biotype: protein_coding
description:
  DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]


ensembl_gene_id: SCAB_40831
symbol: hppA
gene_biotype: protein_coding
description:
  Putative pyrophosphate-energized proton pump; Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.


ensembl_gene_id: SCAB_41241
symbol: acsA-2
gene_biotype: protein_coding
description:
  Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.


ensembl_gene_id: SCAB_41251
symbol: nhaA
gene_biotype: protein_coding
description:
  Putative sodium/proton antiporter; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.


ensembl_gene_id: SCAB_41301
symbol: nth
gene_biotype: protein_coding
description:
  Putative endonuclease/N-glycosylase; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.


ensembl_gene_id: SCAB_41391
symbol: whiB-7
gene_biotype: protein_coding
description:
  Putative regulatory protein; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.


ensembl_gene_id: SCAB_41451
symbol: CBG71218.1
gene_biotype: protein_coding
description:
  Putative heavy metal reductase; PMID:16672525; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.


ensembl_gene_id: SCAB_41641
symbol: asd1
gene_biotype: protein_coding
description:
  Putative aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.


ensembl_gene_id: SCAB_41781
symbol: recR
gene_biotype: protein_coding
description:
  Putative DNA modification/recombination protein; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.


ensembl_gene_id: SCAB_41791
symbol: CBG71251.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.


ensembl_gene_id: SCAB_41891
symbol: purA
gene_biotype: protein_coding
description:
  Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.


ensembl_gene_id: SCAB_42121
symbol: kynU-2
gene_biotype: protein_coding
description:
  Putative aminotransferase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively.


ensembl_gene_id: SCAB_42131
symbol: kynA
gene_biotype: protein_coding
description:
  Putative tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.


ensembl_gene_id: SCAB_42161
symbol: fba
gene_biotype: protein_coding
description:
  Putative fructose 1,6-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.


ensembl_gene_id: SCAB_42171
symbol: pyrE
gene_biotype: protein_coding
description:
  Putative orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).


ensembl_gene_id: SCAB_42201
symbol: speE
gene_biotype: protein_coding
description:
  Putative spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.


ensembl_gene_id: SCAB_42291
symbol: clpB
gene_biotype: protein_coding
description:
  Chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.


ensembl_gene_id: SCAB_42521
symbol: dnaJ
gene_biotype: protein_coding
description:
  Molecular chaperone; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK [...]


ensembl_gene_id: SCAB_42531
symbol: grpE
gene_biotype: protein_coding
description:
  Heat shock protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depen [...]


ensembl_gene_id: SCAB_42681
symbol: dcd
gene_biotype: protein_coding
description:
  Putative deoxynucleotide triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.


ensembl_gene_id: SCAB_42801
symbol: CBG71349.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein, IS-associated; PMID:16208464; PMID:1650732; association with SCAB042811 suggests IS involvement, see also SCAB42801, SCAB0161/SCAB0171, SCAB44411/SCAB44421.


ensembl_gene_id: SCAB_42811
symbol: CBG71350.1
gene_biotype: protein_coding
description:
  Putative IS transposase; PMID:16339937; PMID:1650732; see also SCAB42801, SCAB0161/SCAB0171, SCAB44411/SCAB44421, same pattern of apparent overlap; TTA-Leu codon(s) 96 may indicate regulation by BldA.


ensembl_gene_id: SCAB_42901
symbol: CBG71360.1
gene_biotype: protein_coding
description:
  Putative IS transposase; PMID: 1332944; overlaps SCAB42902 seems to be common pattern see also SCAB0371, SCAB0691, SCAB0991, SCAB23721, SCAB90821.


ensembl_gene_id: SCAB_43031
symbol: CBG71373.1
gene_biotype: protein_coding
description:
  Putative ABC transporter transmembrane subunit; Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: SCAB_43221
symbol: CBG71392.1
gene_biotype: protein_coding
description:
  Putative ABC transporter transmembrane subunit; Cluster 0482 with SCAB21001; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: SCAB_43281
symbol: sspG
gene_biotype: protein_coding
description:
  Putative polyketide-based spore pigment synthesis protein; PMID: 1644304; PMID:15365693; PMID: 8344517; spore pigment.


ensembl_gene_id: SCAB_43291
symbol: sppH
gene_biotype: protein_coding
description:
  Putative whiE protein II; PMID: 1644304; PMID:15365693; PMID: 8344517; PMID:12323376; spore pigment.


ensembl_gene_id: SCAB_43301
symbol: sppA
gene_biotype: protein_coding
description:
  Putative polyketide beta-ketoacyl synthase 1; PMID:12323376; PMID:15365693; PMID: 8344517; PMID:11959542; spore pigment; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: SCAB_43311
symbol: sppB
gene_biotype: protein_coding
description:
  Putative polyketide beta-ketoacyl synthase 2; PMID: 8344517; PMID: 1644304; PMID: 2077356; PMID:15365693; PMID: 7592377; spore pigment; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: SCAB_43321
symbol: sppC
gene_biotype: protein_coding
description:
  Putative polyketide synthase acyl carrier protein; PMID: 2077356; PMID: 1644304; PMID: 8344517; PMID: 1527048; spore pigment.


ensembl_gene_id: SCAB_43881
symbol: CBG71452.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.


ensembl_gene_id: SCAB_43931
symbol: CBG71457.1
gene_biotype: protein_coding
description:
  Putative regulatory protein phosphatase; PMID:11731481; TTA-Leu codon(s) 104 may indicate regulation by BldA.


ensembl_gene_id: SCAB_44031
symbol: CBG71467.1
gene_biotype: protein_coding
description:
  Putative monooxgenase; PMID:16428858; PMID: 7737473; PMID:15561847; Belongs to the cytochrome P450 family.


ensembl_gene_id: SCAB_44241
symbol: CBG71487.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; PMID:16632251; TTA-Leu codon(s) 148 may indicate regulation by BldA.


ensembl_gene_id: SCAB_44411
symbol: CBG71503.1
gene_biotype: protein_coding
description:
  Putative IS transposase; PMID:1650732; see also SCAB44421, SCAB0161/SCAB0171, SCAB42801/SCAB42811, same pattern of apparent overlap; TTA-Leu codon(s) 96 may indicate regulation by BldA.


ensembl_gene_id: SCAB_44421
symbol: CBG71504.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Association with SCAB44411 suggests IS involvement, see also SCAB0161/0171, SCAB42801/SCAB42811.


ensembl_gene_id: SCAB_44841
symbol: metG
gene_biotype: protein_coding
description:
  Putative methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.


ensembl_gene_id: SCAB_44991
symbol: aspS
gene_biotype: protein_coding
description:
  aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.


ensembl_gene_id: SCAB_45271
symbol: CBG71590.1
gene_biotype: protein_coding
description:
  Putative molybdenum cofactor biosynthesis protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.


ensembl_gene_id: SCAB_45281
symbol: CBG71591.1
gene_biotype: protein_coding
description:
  Putative molybdopterin-guanine dinucleotide biosynthesis protein; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family.


ensembl_gene_id: SCAB_45441
symbol: azoR
gene_biotype: protein_coding
description:
  Putative dehydrogenase flavoprotein; Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity; Belongs to the azoreductase type 1 family.


ensembl_gene_id: SCAB_45651
symbol: CBG71626.1
gene_biotype: protein_coding
description:
  Putative peptidylprolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.


ensembl_gene_id: SCAB_45751
symbol: gyrA
gene_biotype: protein_coding
description:
  DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.


ensembl_gene_id: SCAB_45761
symbol: gyrB
gene_biotype: protein_coding
description:
  DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.


ensembl_gene_id: SCAB_45791
symbol: recF
gene_biotype: protein_coding
description:
  DNA replication protein; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family.


ensembl_gene_id: SCAB_45811
symbol: dnaN
gene_biotype: protein_coding
description:
  DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...]


ensembl_gene_id: SCAB_45821
symbol: dnaA
gene_biotype: protein_coding
description:
  Chromosomal replication initiator protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.


ensembl_gene_id: SCAB_45851
symbol: CBG71644.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family.


ensembl_gene_id: SCAB_45881
symbol: gidB
gene_biotype: protein_coding
description:
  Glucose inhibited division protein; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.


ensembl_gene_id: SCAB_45901
symbol: parB
gene_biotype: protein_coding
description:
  Putative chromosome partitioning nuclease; PMID:10671452; PMID: 1577691; PMID: 9795152; Belongs to the ParB family.


ensembl_gene_id: SCAB_45991
symbol: CBG71658.1
gene_biotype: protein_coding
description:
  Putative RNA nucleotidyltransferase; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.


ensembl_gene_id: SCAB_46161
symbol: dnaB
gene_biotype: protein_coding
description:
  Putative replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily.


ensembl_gene_id: SCAB_46241
symbol: CBG71680.1
gene_biotype: protein_coding
description:
  Putative LysR-family transcriptional regulator; TTA-Leu codon(s) 5, 89 may indicate regulation by BldA; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: SCAB_46341
symbol: thiC
gene_biotype: protein_coding
description:
  Putative thiamine biosynthesis protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.


ensembl_gene_id: SCAB_46391
symbol: pat
gene_biotype: protein_coding
description:
  Putative aminotransferase; May catalyze the transamination reaction in phenylalanine biosynthesis; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: SCAB_46461
symbol: kptA
gene_biotype: protein_coding
description:
  Putative phosphotransferase; Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''- cyclic phosphate (APPR>P). May function as an ADP-ribosylase.


ensembl_gene_id: SCAB_46561
symbol: serS
gene_biotype: protein_coding
description:
  serine-tRNA ligase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).


ensembl_gene_id: SCAB_46581
symbol: CBG71712.1
gene_biotype: protein_coding
description:
  Putative peroxidase; Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the tetrapyrrol ring intact. Belongs to the DyP-type peroxidase family.


ensembl_gene_id: SCAB_46971
symbol: SCAB_46971
gene_biotype: protein_coding
description:
  Putative replication initiator protein; PMID: 9620953; PMID: 9851040; pseudo: missing start codon, stop codon in wrong place too.


ensembl_gene_id: SCAB_47081
symbol: SCAB_47081
gene_biotype: protein_coding
description:
  Conserved hypothetical protein (fragment); Pseudo missing stop codon - gene fragment; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: SCAB_47321
symbol: tadA
gene_biotype: protein_coding
description:
  Putative deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.


ensembl_gene_id: SCAB_47351
symbol: upp
gene_biotype: protein_coding
description:
  Putative uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.


ensembl_gene_id: SCAB_4751
symbol: gap
gene_biotype: protein_coding
description:
  Glyceraldehyde 3-phosphate dehydrogenase; Cluster 0095 with SCAB10521, SCAB69701, SCAB83281; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.


ensembl_gene_id: SCAB_47561
symbol: CBG71810.1
gene_biotype: protein_coding
description:
  Putative pyridoxal phosphate binding aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: SCAB_47691
symbol: dnaZ
gene_biotype: protein_coding
description:
  Putative DNA polymerase subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.


ensembl_gene_id: SCAB_4771
symbol: SCAB_4771
gene_biotype: protein_coding
description:
  Putative integral membrane protein; No significant db matches; TTA-Leu codon(s) 13 may indicate regulation by BldA.


ensembl_gene_id: SCAB_47791
symbol: purS
gene_biotype: protein_coding
description:
  Putative purine biosynthesis protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the tr [...]


ensembl_gene_id: SCAB_47801
symbol: purQ
gene_biotype: protein_coding
description:
  Phosphoribosyl formylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist  [...]


ensembl_gene_id: SCAB_47811
symbol: purL
gene_biotype: protein_coding
description:
  Phosphoribosyl formylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...]


ensembl_gene_id: SCAB_47851
symbol: purF
gene_biotype: protein_coding
description:
  Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.


ensembl_gene_id: SCAB_47881
symbol: vdh
gene_biotype: protein_coding
description:
  Valine dehydrogenase (EC 1.4.1.-); PMID: 8320231; PMID: 8921870; PMID:10612726; PMID: 7928973; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.


ensembl_gene_id: SCAB_48621
symbol: CBG71915.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; PMID:2180909; cluster 0723 with SCAB52701; C terminal half of protein match with Saccharopolyspora erythraea hypothetical protein near xis excision nuclease.


ensembl_gene_id: SCAB_48701
symbol: CBG71924.1
gene_biotype: protein_coding
description:
  Putative phosphatase; TTA-Leu codon(s) 5 may indicate regulation by BldA; Belongs to the 5'-nucleotidase family.


ensembl_gene_id: SCAB_49001
symbol: ribA-2
gene_biotype: protein_coding
description:
  Putative GTP cyclohydrolase protein; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family.


ensembl_gene_id: SCAB_49051
symbol: trmB
gene_biotype: protein_coding
description:
  Putative methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.


ensembl_gene_id: SCAB_49301
symbol: CBG71981.1
gene_biotype: protein_coding
description:
  Putative berberine bridge enzyme; PMID:12323376; PMID:9387157; PMID:10099135; cluster 0356 with SCAB11901.


ensembl_gene_id: SCAB_49311
symbol: pstS
gene_biotype: protein_coding
description:
  Putative high-affinity phosphate-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import; Belongs to the PstS family.


ensembl_gene_id: SCAB_49321
symbol: pstC
gene_biotype: protein_coding
description:
  Phosphate ABC transporter transmembrane subunit; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: SCAB_49341
symbol: pstB
gene_biotype: protein_coding
description:
  Phosphate ABC transport system ATP-binding subunit; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.


ensembl_gene_id: SCAB_49421
symbol: ppk
gene_biotype: protein_coding
description:
  Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family.


ensembl_gene_id: SCAB_49481
symbol: mshD
gene_biotype: protein_coding
description:
  Putative acetyltransferase; Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.


ensembl_gene_id: SCAB_49671
symbol: CBG72016.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; May play a role in the intracellular transport of hydrophobic ligands.


ensembl_gene_id: SCAB_49701
symbol: dtd
gene_biotype: protein_coding
description:
  Putative aminoacyl-tRNA hydrolase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family.


ensembl_gene_id: SCAB_49711
symbol: amfC
gene_biotype: protein_coding
description:
  Putative aerial mycelium formation regulatory protein; PMID: 7592414; S. coelicolor and S. griseus amfC only 60%, this CDS has same level of match to both.


ensembl_gene_id: SCAB_49901
symbol: mshA
gene_biotype: protein_coding
description:
  Putative glycosyltransferase; Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2- deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.


ensembl_gene_id: SCAB_49912
symbol: CBG72040.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Maybe pseudo: overlaps SCAB49911 but strong fasta matches to predicted proteins in other organisms.


ensembl_gene_id: SCAB_49941
symbol: gpmA
gene_biotype: protein_coding
description:
  Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.


ensembl_gene_id: SCAB_50091
symbol: ispD
gene_biotype: protein_coding
description:
  Putative 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).


ensembl_gene_id: SCAB_50101
symbol: ispF
gene_biotype: protein_coding
description:
  2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).


ensembl_gene_id: SCAB_50121
symbol: CBG72058.1
gene_biotype: protein_coding
description:
  Putative RNA methyltransferase; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.


ensembl_gene_id: SCAB_50161
symbol: msiK
gene_biotype: protein_coding
description:
  Putative maltose/cellubiose ABC transporter ATP-binding subunit; PMID: 9068663; PMID: 7494485; Belongs to the ABC transporter superfamily.


ensembl_gene_id: SCAB_5021
symbol: SCAB_5021
gene_biotype: protein_coding
description:
  Putative integral membrane protein; No significant db matches; TTA-Leu codon(s) 21 may indicate regulation by BldA.


ensembl_gene_id: SCAB_50371
symbol: CBG72083.1
gene_biotype: protein_coding
description:
  Putative trehalose phosphatase; Removes the phosphate from trehalose 6-phosphate to produce free trehalose.


ensembl_gene_id: SCAB_50441
symbol: groEL2
gene_biotype: protein_coding
description:
  Chaperonin 2; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.


ensembl_gene_id: SCAB_50591
symbol: murQ
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate.


ensembl_gene_id: SCAB_50761
symbol: CBG72120.1
gene_biotype: protein_coding
description:
  Putative ATP-binding protein; IstB-like domain often associated with IS; 3 TMHs suggest membrane location; TTA-Leu codon(s) 57 may indicate regulation by BldA.


ensembl_gene_id: SCAB_50831
symbol: mqnD
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily.


ensembl_gene_id: SCAB_50841
symbol: mqnB
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2).


ensembl_gene_id: SCAB_51001
symbol: CBG72143.1
gene_biotype: protein_coding
description:
  Putative tRNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family.


ensembl_gene_id: SCAB_51011
symbol: CBG72144.1
gene_biotype: protein_coding
description:
  Putative oxidoreductase; PMID:16723573; PMID:9353926; possibly regulatory domain subunit for ion channel (from PF00248).


ensembl_gene_id: SCAB_51101
symbol: serC
gene_biotype: protein_coding
description:
  Putative phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.


ensembl_gene_id: SCAB_51331
symbol: pdxH
gene_biotype: protein_coding
description:
  Putative pyridoxamine oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).


ensembl_gene_id: SCAB_51411
symbol: CBG72182.1
gene_biotype: protein_coding
description:
  Putative hydrolase; Codon 37 TTA-Leu (rare) indicates regulation by BldA; TTA-Leu codon(s) 37 may indicate regulation by BldA.


ensembl_gene_id: SCAB_51501
symbol: purU
gene_biotype: protein_coding
description:
  Putative formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).


ensembl_gene_id: SCAB_51851
symbol: CBG72222.1
gene_biotype: protein_coding
description:
  Putative sigma factor; No close matches in S. coelicolor or S. avermitilis; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: SCAB_52081
symbol: vgb
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2- amino-butenoic acid.


ensembl_gene_id: SCAB_52251
symbol: CBG72260.1
gene_biotype: protein_coding
description:
  Putative sodium-coupled transporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: SCAB_52701
symbol: CBG72306.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; PMID:2180909; cluster 0723 with SCAB48621; C terminal half of protein match with Saccharopolyspora erythraea hypothetical protein near xis excision nuclease.


ensembl_gene_id: SCAB_52731
symbol: CBG72309.1
gene_biotype: protein_coding
description:
  Putative phage protein; PMID:9884232; TTA-Leu codon(s) 276 may indicate regulation by BldA; Belongs to the 'phage' integrase family.


ensembl_gene_id: SCAB_52901
symbol: CBG72325.1
gene_biotype: protein_coding
description:
  PMID: 7883183; PMID: 1916276; PMID: 9554855; putative association with SCAB52911/hrdB by inference from PMID: 7883183.


ensembl_gene_id: SCAB_52911
symbol: hrdD
gene_biotype: protein_coding
description:
  Sigma factor HrdD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.


ensembl_gene_id: SCAB_53051
symbol: mscL
gene_biotype: protein_coding
description:
  Putative mechanosensitive ion channel; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.


ensembl_gene_id: SCAB_53071
symbol: CBG72342.1
gene_biotype: protein_coding
description:
  Putative methylthioadenosine phosphorylase; Purine nucleoside phosphorylase involved in purine salvage.


ensembl_gene_id: SCAB_53121
symbol: CBG72347.1
gene_biotype: protein_coding
description:
  Putative 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.


ensembl_gene_id: SCAB_53141
symbol: moeA
gene_biotype: protein_coding
description:
  Putative molybdopterin biosynthesis protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.


ensembl_gene_id: SCAB_53151
symbol: moaC
gene_biotype: protein_coding
description:
  Molybdenum cofactor biosynthesis protein; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.


ensembl_gene_id: SCAB_53311
symbol: CBG72366.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; PMID:11451671; PMID:16079135; PMID:2575701; db matches only to Cterm DUF region; Nterm low complexity, high GC.


ensembl_gene_id: SCAB_53381
symbol: CBG72373.1
gene_biotype: protein_coding
description:
  Putative cobalt ABC transporter system ATP-binding subunit; Part of an ABC transporter complex. Responsible for energy coupling to the transport system.


ensembl_gene_id: SCAB_53391
symbol: CBG72374.1
gene_biotype: protein_coding
description:
  Putative MarR family transcriptional regulator; N-terminal extended compared to db entries; contains Pro-rich tract codons 36-70.


ensembl_gene_id: SCAB_5341
symbol: SCAB_5341
gene_biotype: protein_coding
description:
  Putative sugar transport integral membrane protein; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: SCAB_53501
symbol: CBG72386.1
gene_biotype: protein_coding
description:
  ftsK/spoIIIE family protein; PMID: 7763542; PMID: 8366038; TTA-Leu codon(s) 428 may indicate regulation by BldA.


ensembl_gene_id: SCAB_53521
symbol: CBG72388.1
gene_biotype: protein_coding
description:
  Putative GntR-family transcriptional regulator; PMID:12584005; PMID:14504830; PMID: 9620953; PMID:8366038; PMID:2657820.


ensembl_gene_id: SCAB_53551
symbol: CBG72391.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; PMID:1612433; PMID:2123814; TTA-Leu codon(s) 209 may indicate regulation by BldA.


ensembl_gene_id: SCAB_53811
symbol: rsmI
gene_biotype: protein_coding
description:
  Putative methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.


ensembl_gene_id: SCAB_53861
symbol: rsmA
gene_biotype: protein_coding
description:
  Putative SAM-binding methyltransferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.


ensembl_gene_id: SCAB_53871
symbol: ispE
gene_biotype: protein_coding
description:
  Putative isopentenyl monophosphate kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.


ensembl_gene_id: SCAB_53981
symbol: CBG72434.1
gene_biotype: protein_coding
description:
  Putative secreted peptidase; PMID:12039725; PMID:8990295; PMID:12446651; PMID:12598647; PMID:15112993; Belongs to the peptidase S8 family.


ensembl_gene_id: SCAB_54001
symbol: galE1
gene_biotype: protein_coding
description:
  UDP-glucose 4-epimerase; PMID:3335481; Belongs to the NAD(P)-dependent epimerase/dehydratase family.


ensembl_gene_id: SCAB_54011
symbol: galK
gene_biotype: protein_coding
description:
  Galactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily.


ensembl_gene_id: SCAB_54051
symbol: tam
gene_biotype: protein_coding
description:
  Putative trans-aconitate methyltransferase; Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.


ensembl_gene_id: SCAB_54111
symbol: ppc
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family.


ensembl_gene_id: SCAB_54141
symbol: pth
gene_biotype: protein_coding
description:
  aminoacyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.


ensembl_gene_id: SCAB_54151
symbol: rplY
gene_biotype: protein_coding
description:
  50S ribosomal L25 protein; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.


ensembl_gene_id: SCAB_54161
symbol: prsA2
gene_biotype: protein_coding
description:
  Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.


ensembl_gene_id: SCAB_54171
symbol: glmU
gene_biotype: protein_coding
description:
  Putative nucleotidyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.


ensembl_gene_id: SCAB_5431
symbol: crtV
gene_biotype: protein_coding
description:
  Putative iron-sulfur protein; PMID:10767533; PMID:11200234; PMID:15716454; carotenoid pigment gene cluster.


ensembl_gene_id: SCAB_54321
symbol: mfd
gene_biotype: protein_coding
description:
  Putative transcriptional-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.


ensembl_gene_id: SCAB_54441
symbol: eno
gene_biotype: protein_coding
description:
  Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.


ensembl_gene_id: SCAB_5451
symbol: crtI
gene_biotype: protein_coding
description:
  Putative phytoene dehydrogenase (phytoene desaturase) (putative secreted protein); PMID:8917308; PMID:15716454; carotenoid pigment gene cluster.


ensembl_gene_id: SCAB_54571
symbol: fadA2
gene_biotype: protein_coding
description:
  Putative acetyl-CoA C-acyltransferase; PMID:12101301; Belongs to the thiolase-like superfamily. Thiolase family.


ensembl_gene_id: SCAB_5461
symbol: crtE
gene_biotype: protein_coding
description:
  Putative geranylgeranyl pyrophosphate synthase; PMID:8917308; PMID:15716454; carotenoid pigment gene cluster; Belongs to the FPP/GGPP synthase family.


ensembl_gene_id: SCAB_5471
symbol: litS
gene_biotype: protein_coding
description:
  Putative sigma factor; PMID:15716454; cluster 0758 with SCAB85121; carotenoid pigment gene cluster; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: SCAB_54751
symbol: CBG72506.1
gene_biotype: protein_coding
description:
  SigL-like sigma factor; PMID:14597396; PMID:9115095; PMID:10071227; PMID:9826694; PMID:15292136; PMID:7770044; PMID:10517579; Belongs to the sigma-70 factor family.


ensembl_gene_id: SCAB_54761
symbol: CBG72507.1
gene_biotype: protein_coding
description:
  Putative anti sigma factor antagonist; PMID:6088674; PMID:15793135; Belongs to the anti-sigma-factor antagonist family.


ensembl_gene_id: SCAB_54851
symbol: purK
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazole carboxylase ATPase subunit PurK; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).


ensembl_gene_id: SCAB_54861
symbol: purE
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazole carboxylase catalytic subunit PurE; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).


ensembl_gene_id: SCAB_55051
symbol: cofE
gene_biotype: protein_coding
description:
  Putative F420-0:gamma-glutamyl ligase; Bifunctional enzyme that catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L- lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives, and the FMNH2- dependent reduction of dehydro-F420-0 to form F420-0.


ensembl_gene_id: SCAB_55061
symbol: cofD
gene_biotype: protein_coding
description:
  Putative LPPG:Fo 2-phopspho-L-lactate transferase; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP.


ensembl_gene_id: SCAB_55081
symbol: whiB
gene_biotype: protein_coding
description:
  Sporulation regulatory protein; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.


ensembl_gene_id: SCAB_55181
symbol: sahH
gene_biotype: protein_coding
description:
  Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.


ensembl_gene_id: SCAB_55271
symbol: mtnA
gene_biotype: protein_coding
description:
  Putative translation initiation factor; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).


ensembl_gene_id: SCAB_55331
symbol: hpf
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.


ensembl_gene_id: SCAB_55371
symbol: secA
gene_biotype: protein_coding
description:
  Preprotein translocase; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.


ensembl_gene_id: SCAB_55691
symbol: prfB
gene_biotype: protein_coding
description:
  Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.


ensembl_gene_id: SCAB_55731
symbol: ftsX
gene_biotype: protein_coding
description:
  Putative cell division protein; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.


ensembl_gene_id: SCAB_55741
symbol: CBG72603.1
gene_biotype: protein_coding
description:
  Putative carboxy-terminal processing protease precursor; TTA-Leu codon(s) 184 may indicate regulation by BldA.


ensembl_gene_id: SCAB_55751
symbol: smpB
gene_biotype: protein_coding
description:
  Small protein B homologue; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switch [...]


ensembl_gene_id: SCAB_55761
symbol: CBG72605.1
gene_biotype: protein_coding
description:
  Putative LacI-family transcriptional regulator; TTA-Leu codon(s) 69 may indicate regulation by BldA.


ensembl_gene_id: SCAB_55941
symbol: hup
gene_biotype: protein_coding
description:
  DNA-binding protein HU1/hs1; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.


ensembl_gene_id: SCAB_55951
symbol: murA
gene_biotype: protein_coding
description:
  UDP-N-acetylglucosamine transferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.


ensembl_gene_id: SCAB_5631
symbol: SCAB_5631
gene_biotype: protein_coding
description:
  Putative anti-sigma-factor antagonist; PMID:15793135; Belongs to the anti-sigma-factor antagonist family.


ensembl_gene_id: SCAB_56481
symbol: clpS
gene_biotype: protein_coding
description:
  Putative ATP-dependent Clp protease adaptor protein; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family.


ensembl_gene_id: SCAB_56591
symbol: CBG72685.1
gene_biotype: protein_coding
description:
  Putative cytosolic aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. Belongs to the peptidase M17 family.


ensembl_gene_id: SCAB_56731
symbol: rph
gene_biotype: protein_coding
description:
  Putative ribonuclease; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.


ensembl_gene_id: SCAB_56751
symbol: CBG72701.1
gene_biotype: protein_coding
description:
  HAM1 protein homolog; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.


ensembl_gene_id: SCAB_56781
symbol: CBG72704.1
gene_biotype: protein_coding
description:
  Putative 10kD chaperone subunit; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter; Belongs to the GroES chaperonin family.


ensembl_gene_id: SCAB_57221
symbol: CBG72749.1
gene_biotype: protein_coding
description:
  Putative sugar kinase; Product annotation from ROK pfam PF00480; lacks PF08067 Nterm DNA-binding domain.


ensembl_gene_id: SCAB_57271
symbol: CBG72754.1
gene_biotype: protein_coding
description:
  Putative secreted O-glycosylhydrolase; Cluster 0426 with SCAB16431; Belongs to the glycosyl hydrolase family 6.


ensembl_gene_id: SCAB_5741
symbol: SCAB_5741
gene_biotype: protein_coding
description:
  Putative short chain oxidoreductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: SCAB_57821
symbol: ornA
gene_biotype: protein_coding
description:
  Oligoribonuclease; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family.


ensembl_gene_id: SCAB_57831
symbol: adpA
gene_biotype: protein_coding
description:
  A-factor-responsive transcriptional activator; PMID:10540289; TTA-Leu codon(s) 225 may indicate regulation by BldA.


ensembl_gene_id: SCAB_57861
symbol: glmS2
gene_biotype: protein_coding
description:
  Glucosamine--fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.


ensembl_gene_id: SCAB_57921
symbol: desD
gene_biotype: protein_coding
description:
  Putative desferrioxamine (siderophore) biosynthesis protein DesD; PMID: 15600304; PMID:8003107; proposed to catalyze final NTP-dependent reaction: N-acetyl-N-hydroxycadaverine + 2 N-hydroxy-N-succinylcadaverine -> Desferrioxamine B.


ensembl_gene_id: SCAB_57931
symbol: desC
gene_biotype: protein_coding
description:
  Putative desferrioxamine (siderophore) biosynthesis acyl-coA-dependent acetyltranferase DesC; PMID: 15600304; PMID:8003107; proposed reaction: N-hydroxycadaverine + acetyl-CoA <=> N-acetyl-N-hydroxycadaverine + coenzyme A.


ensembl_gene_id: SCAB_57941
symbol: desB
gene_biotype: protein_coding
description:
  Putative desferrioxamine (siderophore) biosynthesis monooxygenase DesB; PMID: 15600304; PMID:10064136; proposed reaction: cadaverine + O2 => N-hydroxycadaverine.


ensembl_gene_id: SCAB_57951
symbol: desA
gene_biotype: protein_coding
description:
  Putative siderophore biosynthesis pyridoxal-dependent decarboxylase DesA; PMID: 15600304; PMID:11274118; proposed reaction L-lysine <=> cadaverine +CO2.


ensembl_gene_id: SCAB_57961
symbol: CBG72820.1
gene_biotype: protein_coding
description:
  Putative IS630 family insertion sequence; Cluster 0138: SCAB35111, SCAB57961, SCAB59871, SCAB87221; no Pfam on first pass: evidence for transposition inferred from duplicates in genome and subthreshold Pfams; TTA-Leu codon(s) 13, 36 may indicate regulation by BldA.


ensembl_gene_id: SCAB_57971
symbol: desE
gene_biotype: protein_coding
description:
  Putative siderophore-interacting protein DesE; PMID:8698519; PMID:8083157; PMID: 15600304; maybe associated with desferrioxamine (siderophore): synthesis upstream see SCAB57921, SCAB57931, SCAB57941, SCAB57951.


ensembl_gene_id: SCAB_58211
symbol: CBG72844.1
gene_biotype: protein_coding
description:
  Putative regulator; PMID:15793135; db matches only to second domain: none with same 2*STAS domain architecture; may bind NTPs PMID:10662676; Belongs to the anti-sigma-factor antagonist family.


ensembl_gene_id: SCAB_58581
symbol: CBG72878.1
gene_biotype: protein_coding
description:
  Binding-protein-dependent transporter ATP-binding subunit; Belongs to the ABC transporter superfamily.


ensembl_gene_id: SCAB_58631
symbol: CBG72883.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Pro/Ala rich; contains repeated aa sequence: codons 116-159/163-205/225-271 and codons 188-234/264-310.


ensembl_gene_id: SCAB_58691
symbol: CBG72888.1
gene_biotype: protein_coding
description:
  Putative carbohydrate transport protein; Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.


ensembl_gene_id: SCAB_58701
symbol: rbsK-2
gene_biotype: protein_coding
description:
  Putative carbohydrate kinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.


ensembl_gene_id: SCAB_58781
symbol: recD2
gene_biotype: protein_coding
description:
  Putative DNA-binding protein; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily.


ensembl_gene_id: SCAB_58791
symbol: citA
gene_biotype: protein_coding
description:
  Citrate synthase; PMID:11325948; see also SCAB51341 putative citrate synthase; Belongs to the citrate synthase family.


ensembl_gene_id: SCAB_5881
symbol: SCAB_5881
gene_biotype: protein_coding
description:
  Probable LysR-family transcriptional regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: SCAB_58811
symbol: CBG72901.1
gene_biotype: protein_coding
description:
  Putative metal-binding protein; B. subtilis copA PMID: 12888353 has architecture like P-type ATPase SCAB58801 plus this CDS; frameshift since divergence of the genera?.


ensembl_gene_id: SCAB_58881
symbol: CBG72908.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; PMID: 9226270; perhaps derived from Iol operon in common ancestor with B. subtilis.


ensembl_gene_id: SCAB_58891
symbol: CBG72909.1
gene_biotype: protein_coding
description:
  Putative carbohydrate kinase; PMID: 9226270; perhaps derived from Iol operon in common ancestor with B. subtilis.


ensembl_gene_id: SCAB_5891
symbol: SCAB_5891
gene_biotype: protein_coding
description:
  Putative Acyl-CoA transferase/carnitine dehydratase protein; Belongs to the CoA-transferase III family.


ensembl_gene_id: SCAB_58921
symbol: CBG72912.1
gene_biotype: protein_coding
description:
  Putative thiamine pyrophosphate-dependent protein; PMID: 9226270; perhaps derived from Iol operon in common ancestor with B. subtilis; Belongs to the TPP enzyme family.


ensembl_gene_id: SCAB_59031
symbol: CBG72923.1
gene_biotype: protein_coding
description:
  Putative secreted protein; PMID:11731481; maybe sortase substrate: LPETGSD signal precedes C-term hydrophobic region.


ensembl_gene_id: SCAB_59241
symbol: melC2
gene_biotype: protein_coding
description:
  Tyrosinase (monophenol monooxygenase); PMID:3932128; PMID:1901488; PMID:2846043; PMID:3002431; PMID:16282322.


ensembl_gene_id: SCAB_59421
symbol: CBG72959.1
gene_biotype: protein_coding
description:
  Putative extracellular transport-associated solute-binding protein; Belongs to the bacterial solute-binding protein 3 family.


ensembl_gene_id: SCAB_59491
symbol: CBG72966.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Has ROK Pfam but lacks N-term ROK HTH domain common to ROK family repressors.


ensembl_gene_id: SCAB_59621
symbol: asd1-2
gene_biotype: protein_coding
description:
  Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.


ensembl_gene_id: SCAB_59731
symbol: sodF2
gene_biotype: protein_coding
description:
  Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.


ensembl_gene_id: SCAB_59761
symbol: ssuB
gene_biotype: protein_coding
description:
  Putative ABC transporter ATP-binding subunit; Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system.


ensembl_gene_id: SCAB_59871
symbol: CBG73003.1
gene_biotype: protein_coding
description:
  Putative transposase; Cluster 0138: SCAB35111, SCAB57961, SCAB59871, SCAB87221; no Pfam: evidence for transposition inferred from 4 exact duplicates in genome; TTA-Leu codon(s) 13, 36 may indicate regulation by BldA.


ensembl_gene_id: SCAB_59931
symbol: tig
gene_biotype: protein_coding
description:
  Putative cell division trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.


ensembl_gene_id: SCAB_59941
symbol: clpP1
gene_biotype: protein_coding
description:
  ATP dependent Clp protease proteolytic subunit 1; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.


ensembl_gene_id: SCAB_59951
symbol: clpP2
gene_biotype: protein_coding
description:
  ATP dependent Clp protease proteolytic subunit 2; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.


ensembl_gene_id: SCAB_59961
symbol: clpX
gene_biotype: protein_coding
description:
  ATP dependent Clp Protease ATP binding subunit; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.


ensembl_gene_id: SCAB_59981
symbol: valS
gene_biotype: protein_coding
description:
  Valyl tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.


ensembl_gene_id: SCAB_60011
symbol: ndk
gene_biotype: protein_coding
description:
  Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.


ensembl_gene_id: SCAB_60151
symbol: rplU
gene_biotype: protein_coding
description:
  Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.


ensembl_gene_id: SCAB_60171
symbol: obg
gene_biotype: protein_coding
description:
  GTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.


ensembl_gene_id: SCAB_60201
symbol: proB
gene_biotype: protein_coding
description:
  Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.


ensembl_gene_id: SCAB_60221
symbol: proA
gene_biotype: protein_coding
description:
  Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.


ensembl_gene_id: SCAB_60281
symbol: nadD
gene_biotype: protein_coding
description:
  Putative nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).


ensembl_gene_id: SCAB_60301
symbol: rsfS
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.


ensembl_gene_id: SCAB_60401
symbol: CBG73059.1
gene_biotype: protein_coding
description:
  Putative ComEC/Rec2 related protein; PMID:7968523; TTA-Leu codon(s) 781 may indicate regulation by BldA.


ensembl_gene_id: SCAB_6041
symbol: secF-2
gene_biotype: protein_coding
description:
  Putative SecDF protein-export membrane protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily.


ensembl_gene_id: SCAB_60711
symbol: CBG73090.1
gene_biotype: protein_coding
description:
  Putative glycosyl transferase; PMID:9405467; PMID:8276791; PMID:9388183; similarity to hasA from Streptococcus equi which may be a virulence factor in animal pathogens, forming a non-immunogenic capsule.


ensembl_gene_id: SCAB_60721
symbol: CBG73091.1
gene_biotype: protein_coding
description:
  Putative phage protein; PMID:9884227; has similarity to protein from phage VWB; found in S. venezuelae PMID:9884227.


ensembl_gene_id: SCAB_61461
symbol: lepA
gene_biotype: protein_coding
description:
  Putative GTP-binding elongation factor; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.


ensembl_gene_id: SCAB_61481
symbol: CBG73170.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Strong matches to receiver domain of two component system response regulator, but no DNA binding domain; cluster 0571 with SCAB25141; TTA-Leu codon(s) 121 may indicate regulation by BldA.


ensembl_gene_id: SCAB_61511
symbol: CBG73173.1
gene_biotype: protein_coding
description:
  Putative oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.


ensembl_gene_id: SCAB_61551
symbol: hrcA
gene_biotype: protein_coding
description:
  Heat-inducible transcriptional repressor of heat shock genes; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons.


ensembl_gene_id: SCAB_61561
symbol: dnaJ2
gene_biotype: protein_coding
description:
  Chaperone protein DnaJ2; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ,  [...]


ensembl_gene_id: SCAB_61581
symbol: sdrD
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.


ensembl_gene_id: SCAB_61631
symbol: rnz
gene_biotype: protein_coding
description:
  Ribonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family.


ensembl_gene_id: SCAB_61641
symbol: CBG73186.1
gene_biotype: protein_coding
description:
  Putative adenosine/AMP deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.


ensembl_gene_id: SCAB_61661
symbol: CBG73188.1
gene_biotype: protein_coding
description:
  Putative glucarate dehydratase; Belongs to the mandelate racemase/muconate lactonizing enzyme family.


ensembl_gene_id: SCAB_61701
symbol: ybeY
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.


ensembl_gene_id: SCAB_61771
symbol: era
gene_biotype: protein_coding
description:
  GTP-binding protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.


ensembl_gene_id: SCAB_61851
symbol: leuA
gene_biotype: protein_coding
description:
  2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.


ensembl_gene_id: SCAB_61931
symbol: uppS
gene_biotype: protein_coding
description:
  Undecaprenyl phosphate synthetase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.


ensembl_gene_id: SCAB_61981
symbol: CBG73219.1
gene_biotype: protein_coding
description:
  Putative metal-binding lipoprotein (transport system associated); Belongs to the bacterial solute-binding protein 9 family.


ensembl_gene_id: SCAB_62001
symbol: glyS
gene_biotype: protein_coding
description:
  glycyl-tRNA synthetase; Catalyzes the attachment of glycine to tRNA(Gly). Belongs to the class-II aminoacyl-tRNA synthetase family.


ensembl_gene_id: SCAB_62091
symbol: CBG73229.1
gene_biotype: protein_coding
description:
  Putative dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.


ensembl_gene_id: SCAB_62241
symbol: cynT
gene_biotype: protein_coding
description:
  Carbonic anyhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family.


ensembl_gene_id: SCAB_62291
symbol: CBG73248.1
gene_biotype: protein_coding
description:
  Putative nitrite/sulphite reductase large subunit; PMID:2445993; PMID:2200672; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.


ensembl_gene_id: SCAB_62361
symbol: CBG73254.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; No full length db matches; N-term PF04542 match; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: SCAB_62411
symbol: CBG73259.1
gene_biotype: protein_coding
description:
  Putative molybdopterin oxidoreductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: SCAB_62461
symbol: CBG73263.1
gene_biotype: protein_coding
description:
  Putative deoxyguanosine triphosphate triphosphohydrolase; PMID: 2826481; Belongs to the dGTPase family. Type 2 subfamily.


ensembl_gene_id: SCAB_62491
symbol: dnaG
gene_biotype: protein_coding
description:
  DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.


ensembl_gene_id: SCAB_62501
symbol: hrdA
gene_biotype: protein_coding
description:
  Principal sigma factor HrdA; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.


ensembl_gene_id: SCAB_62661
symbol: CBG73282.1
gene_biotype: protein_coding
description:
  Putative thioredoxin reductase; PF00072 and PF07992: might receive response from SCAB62671 to modulate oxidoreductase activity?.


ensembl_gene_id: SCAB_62911
symbol: CBG73307.1
gene_biotype: protein_coding
description:
  Putative type I polyketide synthase component; Cluster 0135 collects two pairs: SCAB3291 and SCAB3301, SCAB62911 and SCAB62921.


ensembl_gene_id: SCAB_62921
symbol: CBG73308.1
gene_biotype: protein_coding
description:
  Putative type I polyketide synthase component; PMID:14742212; PMID:12791134; cluster 0135 collects two pairs: SCAB3291 and SCAB3301, SCAB62911 and SCAB62921.


ensembl_gene_id: SCAB_62981
symbol: CBG73314.1
gene_biotype: protein_coding
description:
  Putative phosphopantetheinyl transferase; PMID:12791134; PMID:10954087; PMID:10767533; PMID:9836424; PMID:14742212; PMID:12323376; PMID:2583128; PMID:7476861; PMID:9831526; Belongs to the P-Pant transferase superfamily.


ensembl_gene_id: SCAB_63111
symbol: CBG73326.1
gene_biotype: protein_coding
description:
  Putative secondary metabolite corepressor; PMID: 10792718; PMID:9371444; PMID:9260956; PMID: 12904539; PMID:16228193.


ensembl_gene_id: SCAB_63131
symbol: CBG73328.1
gene_biotype: protein_coding
description:
  Putative two-component sensor kinase; PMID:9831526; TTA-Leu codon(s) 16 may indicate regulation by BldA.


ensembl_gene_id: SCAB_63171
symbol: CBG73332.1
gene_biotype: protein_coding
description:
  Putative regulatory protein; PMID:16452404; PMID:12323376; PMID:14742212; PMID:10628855; PMID:11016846; PMID:12791134; PMID:1729206; PMID:10467127; PMID:16751529; many secondary metabolite regulators in Streptomyces around 50% identity to this.


ensembl_gene_id: SCAB_63221
symbol: CBG73334.1
gene_biotype: protein_coding
description:
  Putative integral membrane efflux protein; PMID:10322037; PMID: 11278540; PMID:8596448; PMID:11050092.


ensembl_gene_id: SCAB_63251
symbol: CBG73336.1
gene_biotype: protein_coding
description:
  Putative secondary metabolite synthesis protein; PMID:7828855; PMID:15271354; PMID:7928998; PMID:12137949; PMID:12399480; PMID:12480894; possible secondary metabolite biosynthesis cluster may extend to SCAB63401.


ensembl_gene_id: SCAB_63281
symbol: CBG73339.1
gene_biotype: protein_coding
description:
  Putative secondary metabolite biosynthesis protein; PMID:15271354; PMID:7828855; PMID:7928998; PMID:12399480; PMID:12137949.


ensembl_gene_id: SCAB_63301
symbol: CBG73341.1
gene_biotype: protein_coding
description:
  P450-like monoxygenase; PMID: 9804844; PMID:15112993; PMID:10099135; many sequenced genes ~40% aa id: PMID:11137817, PMID:11948863, PMID:7737473, PMID:15561847; Belongs to the cytochrome P450 family.


ensembl_gene_id: SCAB_63741
symbol: CBG73383.1
gene_biotype: protein_coding
description:
  Putative integral membrane protein; PMID:16305230; secondary metabolite genes in other S. sp also have borderline-significant %aa id.


ensembl_gene_id: SCAB_63871
symbol: CBG73394.1
gene_biotype: protein_coding
description:
  Putative transporter; PMID:15313224; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: SCAB_63981
symbol: CBG73404.1
gene_biotype: protein_coding
description:
  Putative transporter transmembrane subunit; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: SCAB_64131
symbol: fabF
gene_biotype: protein_coding
description:
  3-oxoacyl-[acyl-carrier-protein] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.


ensembl_gene_id: SCAB_64141
symbol: fabC
gene_biotype: protein_coding
description:
  Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.


ensembl_gene_id: SCAB_64151
symbol: fabH
gene_biotype: protein_coding
description:
  3-oxoacyl-[acyl-carrier-protein] synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.


ensembl_gene_id: SCAB_64161
symbol: fabD
gene_biotype: protein_coding
description:
  Malonyl CoA:acyl carrier protein malonyltransferase; PMID:7626609; PMID:15569690; PMID:7608065; PMID:8824610.


ensembl_gene_id: SCAB_64301
symbol: CBG73436.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


ensembl_gene_id: SCAB_6501
symbol: SCAB_6501
gene_biotype: protein_coding
description:
  Putative transport system permease protein; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: SCAB_6561
symbol: kgdA
gene_biotype: protein_coding
description:
  Putative KHG/KDPG aldolase [includes: 4-hydroxy-2-oxoglutarate aldolase; 2-dehydro-3-deoxy-phosphogluconate aldolase].


ensembl_gene_id: SCAB_66251
symbol: CBG73624.1
gene_biotype: protein_coding
description:
  Putative membrane protein; Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the tetrapyrrol ring intact. Belongs to the DyP-type peroxidase family.


ensembl_gene_id: SCAB_6631
symbol: SCAB_6631
gene_biotype: protein_coding
description:
  Putative acyl-CoA thiolase; PMID:15563836; Belongs to the thiolase-like superfamily. Thiolase family.


ensembl_gene_id: SCAB_66361
symbol: CBG73636.1
gene_biotype: protein_coding
description:
  Probable ABC-transporter transmembrane subunit; PMID:8326867; PMID:15837373; PMID:9696745; PMID:1924314.


ensembl_gene_id: SCAB_66381
symbol: panB
gene_biotype: protein_coding
description:
  3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11); Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.


ensembl_gene_id: SCAB_66401
symbol: CBG73639.1
gene_biotype: protein_coding
description:
  Putative efflux transporter protein; PMID:15112993; PMID:1766437; PMID:10322037; related proteins in secondary metabolite / antibiotic efflux; Belongs to the major facilitator superfamily.


ensembl_gene_id: SCAB_66451
symbol: nadE
gene_biotype: protein_coding
description:
  Putative carbon-nitrogen ligase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.


ensembl_gene_id: SCAB_66491
symbol: CBG73648.1
gene_biotype: protein_coding
description:
  Putative glutamine synthetase (EC 6.3.1.2); PMID:11719184; Belongs to the glutamine synthetase family.


ensembl_gene_id: SCAB_66531
symbol: glnE
gene_biotype: protein_coding
description:
  Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...]


ensembl_gene_id: SCAB_66551
symbol: CBG73654.1
gene_biotype: protein_coding
description:
  Putative LysR-family transcriptional regulator; PMID: 12940979; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: SCAB_66641
symbol: CBG73663.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Has below-significant matches to insulin-like growth factor and alpha-amylase inhibitors.


ensembl_gene_id: SCAB_66701
symbol: CBG73669.1
gene_biotype: protein_coding
description:
  Putative secreted carbohydrate debranching enzyme; PMID:8424949; Belongs to the glycosyl hydrolase 13 family.


ensembl_gene_id: SCAB_66711
symbol: CBG73670.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; PMID:15313224; PMID:16632251; PF00072, PF07228 suggest role in regulatory cascade?; TTA-Leu codon(s) 534 may indicate regulation by BldA.


ensembl_gene_id: SCAB_6681
symbol: SCAB_6681
gene_biotype: protein_coding
description:
  Glutamate-cysteine ligase family protein; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.


ensembl_gene_id: SCAB_66921
symbol: lipA
gene_biotype: protein_coding
description:
  Putative lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.


ensembl_gene_id: SCAB_66931
symbol: lipB
gene_biotype: protein_coding
description:
  Putative lipoate-protein ligase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.


ensembl_gene_id: SCAB_67031
symbol: CBG73702.1
gene_biotype: protein_coding
description:
  Putative oxoglutarate dehydrogenase (succinyl-transferring); Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


ensembl_gene_id: SCAB_67051
symbol: CBG73704.1
gene_biotype: protein_coding
description:
  Putative dihydrolipoyllysine-residue succinyltransferase; PMID:8504804; pair of direct repeats and Pro/Ala tract (entirely G/C).


ensembl_gene_id: SCAB_67071
symbol: pepA
gene_biotype: protein_coding
description:
  Putative cytosol aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.


ensembl_gene_id: SCAB_67091
symbol: cobS
gene_biotype: protein_coding
description:
  Putative cobalamin-5'-phosphate synthase (EC:2.7.8.26); Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.


ensembl_gene_id: SCAB_67121
symbol: cobT
gene_biotype: protein_coding
description:
  Putativenicotinate-nucleotide-dimethylbenzimida zo lephosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).


ensembl_gene_id: SCAB_67141
symbol: cobU
gene_biotype: protein_coding
description:
  Putative cobalamin biosynthesis protein; Likely adenosylcobinamide kinase/adenosylcobinamide phosphate guanylyltransferase activity as in PMID: 7559521.


ensembl_gene_id: SCAB_67221
symbol: CBG73721.1
gene_biotype: protein_coding
description:
  Putative integral membrane efflux protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: SCAB_67231
symbol: nadA
gene_biotype: protein_coding
description:
  Putative quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.


ensembl_gene_id: SCAB_67301
symbol: ctaD1
gene_biotype: protein_coding
description:
  Putative cytochrome c oxidase subunit I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.


ensembl_gene_id: SCAB_6731
symbol: icmF
gene_biotype: protein_coding
description:
  Putative methylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.


ensembl_gene_id: SCAB_67311
symbol: CBG73730.1
gene_biotype: protein_coding
description:
  Putative membrane protein; Part of cytochrome c oxidase, its function is unknown. Belongs to the cytochrome c oxidase bacterial subunit CtaF family.


ensembl_gene_id: SCAB_67381
symbol: trpD1
gene_biotype: protein_coding
description:
  Phosphoribosylanthranilate transferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).


ensembl_gene_id: SCAB_67491
symbol: CBG73748.1
gene_biotype: protein_coding
description:
  Putative secreted protein; PMID:15123265; PMID:10194345; PMID:11094342; PMID:7811062; PMID:11466283.


ensembl_gene_id: SCAB_6751
symbol: SCAB_6751
gene_biotype: protein_coding
description:
  Putative secreted calcium-binding protein; PF00353 calcium binding repeats but no sign of PF02382 or PF08339 to support hemolysin-like function.


ensembl_gene_id: SCAB_67621
symbol: pfkA1
gene_biotype: protein_coding
description:
  6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.


ensembl_gene_id: SCAB_67661
symbol: aroH
gene_biotype: protein_coding
description:
  Putative 3-deoxy-7-phosphoheptulonate synthase; PMID:8760910; cluster 0167 with SCAB12021 and SCAB1981; Belongs to the class-II DAHP synthase family.


ensembl_gene_id: SCAB_67681
symbol: bfr
gene_biotype: protein_coding
description:
  Putative bacterioferritin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family.


ensembl_gene_id: SCAB_67701
symbol: nfo
gene_biotype: protein_coding
description:
  Putative endonuclease; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.


ensembl_gene_id: SCAB_67721
symbol: thiG
gene_biotype: protein_coding
description:
  Putative thiazole biosynthesis protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.


ensembl_gene_id: SCAB_67781
symbol: thiE
gene_biotype: protein_coding
description:
  Putative thiamin phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.


ensembl_gene_id: SCAB_67791
symbol: metF
gene_biotype: protein_coding
description:
  5,10-methylenetetrahydrofolate reductase; PMID:12446651; PMID:9515933; Belongs to the methylenetetrahydrofolate reductase family.


ensembl_gene_id: SCAB_67921
symbol: rsmH
gene_biotype: protein_coding
description:
  Putative SAM-dependent methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.


ensembl_gene_id: SCAB_67961
symbol: murE
gene_biotype: protein_coding
description:
  putativeUDP-N-acetylmuramoyl-L-alanyl-D-glutama te--2,6-diaminopimelateligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.


ensembl_gene_id: SCAB_67971
symbol: murF
gene_biotype: protein_coding
description:
  putativeUDP-N-acetylmuramoyl-tripeptide--D-alan yl-D-alanineligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.


ensembl_gene_id: SCAB_67981
symbol: murX
gene_biotype: protein_coding
description:
  putativephospho-N-acetylmuramoyl-pentapeptide-t ra nsferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.


ensembl_gene_id: SCAB_67991
symbol: murD
gene_biotype: protein_coding
description:
  Putative UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.


ensembl_gene_id: SCAB_68011
symbol: murG
gene_biotype: protein_coding
description:
  Putativeundecaprenyldiphospho-muramoylpentapept id eb-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.


ensembl_gene_id: SCAB_68021
symbol: ftsQ
gene_biotype: protein_coding
description:
  Cell division protein; Essential cell division protein; Belongs to the FtsQ/DivIB family. FtsQ subfamily.


ensembl_gene_id: SCAB_68031
symbol: ftsZ
gene_biotype: protein_coding
description:
  Cell division protein; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.


ensembl_gene_id: SCAB_68051
symbol: CBG73802.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.


ensembl_gene_id: SCAB_68081
symbol: CBG73805.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Possible coiled coil region and MQQGG repeats and degenerate repeat regions.


ensembl_gene_id: SCAB_68091
symbol: ileS
gene_biotype: protein_coding
description:
  Putative isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.


ensembl_gene_id: SCAB_68121
symbol: lspA
gene_biotype: protein_coding
description:
  Putative lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.


ensembl_gene_id: SCAB_68131
symbol: CBG73809.1
gene_biotype: protein_coding
description:
  Putative RNA pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.


ensembl_gene_id: SCAB_6831
symbol: fdhD
gene_biotype: protein_coding
description:
  Putative oxidoreductase, FdhD family; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.


ensembl_gene_id: SCAB_68351
symbol: hisD
gene_biotype: protein_coding
description:
  Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.


ensembl_gene_id: SCAB_68361
symbol: hisC
gene_biotype: protein_coding
description:
  Histidinol-phosphate aminotransferase; PMID:2199329; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.


ensembl_gene_id: SCAB_68381
symbol: CBG73834.1
gene_biotype: protein_coding
description:
  Putative membrane protein; PMID:2199329; product not characterised in His cluster investigation PMID:2199329.


ensembl_gene_id: SCAB_68391
symbol: hisH
gene_biotype: protein_coding
description:
  Imidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.


ensembl_gene_id: SCAB_68401
symbol: priA
gene_biotype: protein_coding
description:
  Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Involved in both the histidine and tryptophan biosynthetic pathways; Belongs to the HisA/HisF family.


ensembl_gene_id: SCAB_68421
symbol: hisF
gene_biotype: protein_coding
description:
  Putative imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.


ensembl_gene_id: SCAB_68441
symbol: hisI
gene_biotype: protein_coding
description:
  Putative phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.


ensembl_gene_id: SCAB_68451
symbol: trpE3
gene_biotype: protein_coding
description:
  Putative anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high [...]


ensembl_gene_id: SCAB_68501
symbol: trpB
gene_biotype: protein_coding
description:
  Tryptophan synthase beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.


ensembl_gene_id: SCAB_68511
symbol: trpA
gene_biotype: protein_coding
description:
  Tryptophan synthase alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.


ensembl_gene_id: SCAB_68531
symbol: lgt1
gene_biotype: protein_coding
description:
  Putative prolipoprotein diacyleglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.


ensembl_gene_id: SCAB_68841
symbol: SCAB_68841
gene_biotype: protein_coding
description:
  Putative insertion sequence; PMID:16208464; cluster 0034: SCAB14601, SCAB16631, SCAB24421, SCAB30531, SCAB30841, SCAB68821, SCAB87301; pseudo: frameshift after codon 113; cluster 0050 6: SCAB16641, SCAB24431, SCAB30541, SCAB30831, SCAB68821, SCAB87291; Belongs to the 5'-nucleotidase family.


ensembl_gene_id: SCAB_68911
symbol: CBG73886.1
gene_biotype: protein_coding
description:
  Putative ABC transporter integral membrane subunit; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: SCAB_68981
symbol: polA
gene_biotype: protein_coding
description:
  DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.


ensembl_gene_id: SCAB_69081
symbol: coaE
gene_biotype: protein_coding
description:
  dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.


ensembl_gene_id: SCAB_69391
symbol: psuG
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway; Belongs to the pseudouridine-5'-phosphate glycosidase family.


ensembl_gene_id: SCAB_69401
symbol: CBG73934.1
gene_biotype: protein_coding
description:
  Putative DNA-methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.


ensembl_gene_id: SCAB_69431
symbol: uvrB
gene_biotype: protein_coding
description:
  ABC excision nuclease subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissoc [...]


ensembl_gene_id: SCAB_69501
symbol: aroQ-2
gene_biotype: protein_coding
description:
  Dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.


ensembl_gene_id: SCAB_6951
symbol: folD-2
gene_biotype: protein_coding
description:
  Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.


ensembl_gene_id: SCAB_69561
symbol: uvrA
gene_biotype: protein_coding
description:
  Putative ABC excision nuclease subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.


ensembl_gene_id: SCAB_69651
symbol: uvrC
gene_biotype: protein_coding
description:
  ABC excision nuclease subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.


ensembl_gene_id: SCAB_69671
symbol: CBG73961.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family.


ensembl_gene_id: SCAB_69701
symbol: gap-2
gene_biotype: protein_coding
description:
  Glyceraldehyde-3-phosphate dehydrogenase; Cluster 0095 with SCAB4751, SCAB10521, SCAB83281; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.


ensembl_gene_id: SCAB_69721
symbol: tpiA
gene_biotype: protein_coding
description:
  Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.


ensembl_gene_id: SCAB_69731
symbol: secG
gene_biotype: protein_coding
description:
  Protein-export membrane protein; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.


ensembl_gene_id: SCAB_69741
symbol: rbpA
gene_biotype: protein_coding
description:
  Putative electron transport protein; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.


ensembl_gene_id: SCAB_69821
symbol: CBG73976.1
gene_biotype: protein_coding
description:
  Putative secondary metabolite synthesis protein; PMID:2684656; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: SCAB_69851
symbol: CBG73979.1
gene_biotype: protein_coding
description:
  Putative secondary metabolite synthesis protein; PMID:10212227; PMID:12423351; TTA-Leu codon(s) 44 may indicate regulation by BldA.


ensembl_gene_id: SCAB_69901
symbol: zwf
gene_biotype: protein_coding
description:
  Putative glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.


ensembl_gene_id: SCAB_69921
symbol: tktA
gene_biotype: protein_coding
description:
  Transketolase A; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.


ensembl_gene_id: SCAB_69941
symbol: ctaB
gene_biotype: protein_coding
description:
  Putative cytochrome oxidase assembly factor; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.


ensembl_gene_id: SCAB_70071
symbol: CBG74000.1
gene_biotype: protein_coding
description:
  Putative aminotransferase; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: SCAB_70081
symbol: CBG74001.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; May be associated with iron-sulphur cluster assembly - with SCAB70051?.


ensembl_gene_id: SCAB_70141
symbol: dapD
gene_biotype: protein_coding
description:
  Putative transferase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.


ensembl_gene_id: SCAB_70181
symbol: dapA2
gene_biotype: protein_coding
description:
  Putative dihydrodipicolinate synthase 2; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).


ensembl_gene_id: SCAB_70221
symbol: CBG74015.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; PMID:11731481; PMID:15817470; PMID:1766437; PMID:11325225; many similar proteins in antibiotic biosynth clusters.


ensembl_gene_id: SCAB_7031
symbol: cudB
gene_biotype: protein_coding
description:
  Putative choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.


ensembl_gene_id: SCAB_70521
symbol: CBG74045.1
gene_biotype: protein_coding
description:
  Putative secreted bifunctional pectate lyase/pectinesterase; No full length matches: N term, Erwinia pectate lyase P0C1A4; C term, Bacillus pectinesterase domain AB062880; TTA-Leu codon(s) 9 may indicate regulation by BldA.


ensembl_gene_id: SCAB_70721
symbol: ectC
gene_biotype: protein_coding
description:
  Putative L-ectoine synthase; Catalyzes the circularization of gamma-N-acetyl-alpha,gamma- diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4- pyrimidine carboxylic acid), which is an excellent osmoprotectant.


ensembl_gene_id: SCAB_70731
symbol: ectB
gene_biotype: protein_coding
description:
  Putative diaminobutyrate--2-oxoglutarate transaminase (ectoine biosynthesis); Catalyzes reversively the conversion of L-aspartate beta- semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: SCAB_70741
symbol: ectA
gene_biotype: protein_coding
description:
  Putative L-2,4-diaminobutyric acid acetyltransferase; Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A.


ensembl_gene_id: SCAB_70811
symbol: CBG74075.1
gene_biotype: protein_coding
description:
  Putative cobalamin biosynthesis protein; PMID:14612231; 63.376%aaid to S. seoulensis protein PMID:14612231 involved in superoxide dismutase expression; TTA-Leu codon(s) 27 may indicate regulation by BldA.


ensembl_gene_id: SCAB_70841
symbol: cobB
gene_biotype: protein_coding
description:
  Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.


ensembl_gene_id: SCAB_70871
symbol: cobQ
gene_biotype: protein_coding
description:
  Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.


ensembl_gene_id: SCAB_70881
symbol: cobD
gene_biotype: protein_coding
description:
  Cobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.


ensembl_gene_id: SCAB_7091
symbol: fdhF
gene_biotype: protein_coding
description:
  POSSIBLE FORMATE DEHYDROGENASE H FDHF (FORMATE-HYDROGEN-LYASE-LINKED, SELENOCYSTEINE-CONTAINING POLYPEPTIDE) (FORMATE DEHYDROGENASE-H ALPHA SUBUNIT) (FDH-H); Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: SCAB_71081
symbol: CBG74101.1
gene_biotype: protein_coding
description:
  Putative membrane-associated DNA-binding protein; PF04545/PF08281 at Cterm: this protein may bind -35 element of Sigma-70 promoter; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: SCAB_71111
symbol: cstA
gene_biotype: protein_coding
description:
  Carbon starvation protein; PMID:1848300; suggested may be involved in peptide utilisation (by similarity) PMID:1848300.


ensembl_gene_id: SCAB_71251
symbol: moaA
gene_biotype: protein_coding
description:
  Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.


ensembl_gene_id: SCAB_71291
symbol: tyrS
gene_biotype: protein_coding
description:
  tyrosyl-tRNA synthetase (EC 6.1.1.1); Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.


ensembl_gene_id: SCAB_71321
symbol: fabG
gene_biotype: protein_coding
description:
  Putative 3-oxacyl-(acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: SCAB_71451
symbol: CBG74137.1
gene_biotype: protein_coding
description:
  Putative S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).


ensembl_gene_id: SCAB_71491
symbol: CBG74141.1
gene_biotype: protein_coding
description:
  Putative small secreted protein; PMID:11451672; no significant fasta hits outside Streptomyces genus.


ensembl_gene_id: SCAB_71581
symbol: CBG74149.1
gene_biotype: protein_coding
description:
  Putative DNA glycosylase fragment; 87%aaid to first 86aa of SCO1792; cf SCAB71591 and SCAB71611; Belongs to the DNA glycosylase MPG family.


ensembl_gene_id: SCAB_71591
symbol: CBG74150.1
gene_biotype: protein_coding
description:
  Putative DNA glycosylase; 46%aaid to SCO1792 full length; cf SCAB71581 and 71611; Belongs to the DNA glycosylase MPG family.


ensembl_gene_id: SCAB_71661
symbol: CBG74159.1
gene_biotype: protein_coding
description:
  Putative iron-siderophore uptake system transmembrane component; PMID:16291687; PMID:1838574; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: SCAB_71671
symbol: CBG74160.1
gene_biotype: protein_coding
description:
  Putative iron-siderophore uptake system transmembrane component; PMID:1838574; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: SCAB_71681
symbol: CBG74161.1
gene_biotype: protein_coding
description:
  Putative iron-siderophore uptake system ATP-binding component; Nterminal extension compared with similar proteins poss. encodes TonB receptor protein signature.


ensembl_gene_id: SCAB_71721
symbol: ppnK2
gene_biotype: protein_coding
description:
  Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.


ensembl_gene_id: SCAB_71801
symbol: pyrG
gene_biotype: protein_coding
description:
  Putative CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.


ensembl_gene_id: SCAB_71861
symbol: CBG74177.1
gene_biotype: protein_coding
description:
  Putative ScpA-like chromosome partitioning protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.


ensembl_gene_id: SCAB_71871
symbol: CBG74178.1
gene_biotype: protein_coding
description:
  Putative ScpB-like chromosome partitioning protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.


ensembl_gene_id: SCAB_7191
symbol: kdpC
gene_biotype: protein_coding
description:
  Putative cation transport system component; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.


ensembl_gene_id: SCAB_71951
symbol: CBG74186.1
gene_biotype: protein_coding
description:
  Putative secreted prephenate dehydrogenase/chorismate mutase; PMID:12060705; PMID:10770754; PMID:12480894; Cterm duplicated twice downstream: see SCAB71961 and SCAB71971.


ensembl_gene_id: SCAB_72001
symbol: engA
gene_biotype: protein_coding
description:
  Putative GTPase; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.


ensembl_gene_id: SCAB_7201
symbol: kdpB
gene_biotype: protein_coding
description:
  Putative cation transport system component; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.


ensembl_gene_id: SCAB_72051
symbol: CBG74196.1
gene_biotype: protein_coding
description:
  Putative ABC-transporter subunit; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: SCAB_7211
symbol: kdpA
gene_biotype: protein_coding
description:
  Putative cation transport system component; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane.


ensembl_gene_id: SCAB_72121
symbol: ctaD2
gene_biotype: protein_coding
description:
  Putative cytochrome c oxidase subunit 1-beta; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.


ensembl_gene_id: SCAB_72231
symbol: sprB
gene_biotype: protein_coding
description:
  Secreted serine protease; PMID:7887600; PMID:8868236; PMID:3312129; many other fasta sequences from other streptomycetes.


ensembl_gene_id: SCAB_72281
symbol: CBG74218.1
gene_biotype: protein_coding
description:
  Putative DNA polymerase III, alpha chain; Belongs to the DNA polymerase type-C family. DnaE2 subfamily.


ensembl_gene_id: SCAB_72541
symbol: hmgA
gene_biotype: protein_coding
description:
  Putative homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.


ensembl_gene_id: SCAB_72711
symbol: xlnB
gene_biotype: protein_coding
description:
  Putative secreted endo-1,4-beta-xylanase B (xylanase B); PMID:7533741; PMID:1743521; PMID:15650852; Belongs to the glycosyl hydrolase 11 (cellulase G) family.


ensembl_gene_id: SCAB_73101
symbol: corA-2
gene_biotype: protein_coding
description:
  Putative ion transport protein; Mediates influx of magnesium ions. Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.


ensembl_gene_id: SCAB_73151
symbol: cysS2
gene_biotype: protein_coding
description:
  Putative cysteinyl-tRNA synthetase; Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins; Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.


ensembl_gene_id: SCAB_73191
symbol: mtnA-2
gene_biotype: protein_coding
description:
  Putative initiation factor subunit; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).


ensembl_gene_id: SCAB_73201
symbol: mtnB
gene_biotype: protein_coding
description:
  Putative aldolase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Belongs to the aldolase class II family. MtnB subfamily.


ensembl_gene_id: SCAB_73211
symbol: mtnC
gene_biotype: protein_coding
description:
  Putative hydrolase; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.


ensembl_gene_id: SCAB_73221
symbol: mtnD
gene_biotype: protein_coding
description:
  Putative oxidoreductase; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.


ensembl_gene_id: SCAB_73261
symbol: CBG74312.1
gene_biotype: protein_coding
description:
  Putative ribose transporter transmembrane subunit; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: SCAB_73271
symbol: mtnK
gene_biotype: protein_coding
description:
  5-methylthioribose kinase; Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate.


ensembl_gene_id: SCAB_73291
symbol: glpK1
gene_biotype: protein_coding
description:
  Putative glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.


ensembl_gene_id: SCAB_73301
symbol: glpF
gene_biotype: protein_coding
description:
  Putative glycerol uptake facilitator protein; PMID:3325846; Belongs to the MIP/aquaporin (TC 1.A.8) family.


ensembl_gene_id: SCAB_73321
symbol: metH
gene_biotype: protein_coding
description:
  Putative methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.


ensembl_gene_id: SCAB_73401
symbol: CBG74325.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.


ensembl_gene_id: SCAB_73441
symbol: arc
gene_biotype: protein_coding
description:
  AAA ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.


ensembl_gene_id: SCAB_73461
symbol: pup
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation. Belongs to the prokaryotic ubiquitin-like protein family.


ensembl_gene_id: SCAB_73471
symbol: prcB
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1B family.


ensembl_gene_id: SCAB_73481
symbol: pcrA
gene_biotype: protein_coding
description:
  20S proteasome alpha-subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1A family.


ensembl_gene_id: SCAB_73511
symbol: pafA
gene_biotype: protein_coding
description:
  Putative proteasome component; Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side- chain amino group of a substrate lysine.


ensembl_gene_id: SCAB_73591
symbol: tatA
gene_biotype: protein_coding
description:
  Putative protein-translocation system component; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.


ensembl_gene_id: SCAB_73601
symbol: tatC
gene_biotype: protein_coding
description:
  Putative protein translocation system component; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.


ensembl_gene_id: SCAB_73851
symbol: CBG74370.1
gene_biotype: protein_coding
description:
  Putative glutamine synthetase; Cluster 0495 with SCAB21581; Belongs to the glutamine synthetase family.


ensembl_gene_id: SCAB_73961
symbol: infC
gene_biotype: protein_coding
description:
  Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.


ensembl_gene_id: SCAB_73981
symbol: rplT
gene_biotype: protein_coding
description:
  50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.


ensembl_gene_id: SCAB_73991
symbol: CBG74383.1
gene_biotype: protein_coding
description:
  Putative rRNA methylase; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.


ensembl_gene_id: SCAB_74011
symbol: pheS
gene_biotype: protein_coding
description:
  Putative phenylalanyl-tRNA synthetase alpha chain; SCO1595, SAV6742, have HAMAP MF_00281; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.


ensembl_gene_id: SCAB_74021
symbol: pheT
gene_biotype: protein_coding
description:
  Putative phenylalanyl-tRNA synthetase beta chain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.


ensembl_gene_id: SCAB_74101
symbol: CBG74394.1
gene_biotype: protein_coding
description:
  Putative integral membrane protein; PMID:15302885; PMID:14632285; PMID:9341680; Possible D-cycloserine resistance or regulatory role by similarity with EMBL:AB112918, EMBL:AB001488.


ensembl_gene_id: SCAB_74201
symbol: argC
gene_biotype: protein_coding
description:
  N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.


ensembl_gene_id: SCAB_74211
symbol: argJ
gene_biotype: protein_coding
description:
  Glutamate N-acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.


ensembl_gene_id: SCAB_74221
symbol: argB
gene_biotype: protein_coding
description:
  Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.


ensembl_gene_id: SCAB_74231
symbol: argD
gene_biotype: protein_coding
description:
  Acetylornithine aminotransferase; PMID: 11075930; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.


ensembl_gene_id: SCAB_74251
symbol: apbE2
gene_biotype: protein_coding
description:
  Putative thiamine biosynthesis lipoprotein; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.


ensembl_gene_id: SCAB_74361
symbol: CBG74420.1
gene_biotype: protein_coding
description:
  Conserved hypothetical similar to sigma factor; No automatic HMMPfams: E-values for PF04542(0.0055) PF08281(0.18).


ensembl_gene_id: SCAB_74401
symbol: metN
gene_biotype: protein_coding
description:
  Putative binding-protein-dependent transport system ATP-binding subunit; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.


ensembl_gene_id: SCAB_74421
symbol: CBG74426.1
gene_biotype: protein_coding
description:
  Putative binding-protein-dependent transport system lipoprotein; Belongs to the nlpA lipoprotein family.


ensembl_gene_id: SCAB_74461
symbol: cobT-2
gene_biotype: protein_coding
description:
  Putative phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).


ensembl_gene_id: SCAB_74641
symbol: CBG74446.1
gene_biotype: protein_coding
description:
  Putative extracellular solute-binding lipoprotein; Has 26%aa_id to E. carotovora TogB, pectic oligomer-binding?.


ensembl_gene_id: SCAB_74801
symbol: CBG74461.1
gene_biotype: protein_coding
description:
  Putative phospholipid biosynthetic transferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: SCAB_74841
symbol: pdxS
gene_biotype: protein_coding
description:
  Putative pyridoxal biosynthesis lyase; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family.


ensembl_gene_id: SCAB_74851
symbol: pdxT
gene_biotype: protein_coding
description:
  Putative glutamine amidotransferase subunit; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.


ensembl_gene_id: SCAB_74871
symbol: ruvC
gene_biotype: protein_coding
description:
  Crossover junction endodeoxyribonuclease; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.


ensembl_gene_id: SCAB_74881
symbol: ruvA
gene_biotype: protein_coding
description:
  Holliday junction DNA helicase; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.


ensembl_gene_id: SCAB_74891
symbol: ruvB
gene_biotype: protein_coding
description:
  Holliday junction DNA helicase; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.


ensembl_gene_id: SCAB_74911
symbol: secD
gene_biotype: protein_coding
description:
  Protein-export membrane protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.


ensembl_gene_id: SCAB_74931
symbol: apt
gene_biotype: protein_coding
description:
  Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.


ensembl_gene_id: SCAB_74961
symbol: relA
gene_biotype: protein_coding
description:
  Guanosine 3',5'-bis-pyrophosphate (ppGpp) synthetase RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.


ensembl_gene_id: SCAB_75031
symbol: rspD
gene_biotype: protein_coding
description:
  30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.


ensembl_gene_id: SCAB_75061
symbol: alaS
gene_biotype: protein_coding
description:
  Alanine tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.


ensembl_gene_id: SCAB_75071
symbol: ruvX
gene_biotype: protein_coding
description:
  Putative holliday junction resolvase subunit; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family.


ensembl_gene_id: SCAB_75081
symbol: mltG
gene_biotype: protein_coding
description:
  Putative integral membrane protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family.


ensembl_gene_id: SCAB_75101
symbol: aroC
gene_biotype: protein_coding
description:
  Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.


ensembl_gene_id: SCAB_75111
symbol: aroK
gene_biotype: protein_coding
description:
  Shikimate kinase I; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.


ensembl_gene_id: SCAB_75121
symbol: aroB
gene_biotype: protein_coding
description:
  3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).


ensembl_gene_id: SCAB_75151
symbol: efp
gene_biotype: protein_coding
description:
  Elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.


ensembl_gene_id: SCAB_75161
symbol: nusB
gene_biotype: protein_coding
description:
  Putative NusB-family protein; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.


ensembl_gene_id: SCAB_75181
symbol: pyrR
gene_biotype: protein_coding
description:
  Pyrimidine operon regulatory protein; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.


ensembl_gene_id: SCAB_75191
symbol: pyrB
gene_biotype: protein_coding
description:
  Aspartate carbamoyltransferase; SAV6863 and SCO1487 have HAMAP MF_00001; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.


ensembl_gene_id: SCAB_75201
symbol: pyrC
gene_biotype: protein_coding
description:
  Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.


ensembl_gene_id: SCAB_75241
symbol: pyrD
gene_biotype: protein_coding
description:
  Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.


ensembl_gene_id: SCAB_75281
symbol: rpoZ
gene_biotype: protein_coding
description:
  Putative DNA-directed RNA polymerase omega chain; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.


ensembl_gene_id: SCAB_75291
symbol: CBG74509.1
gene_biotype: protein_coding
description:
  Putative flavoprotein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.


ensembl_gene_id: SCAB_75311
symbol: metK
gene_biotype: protein_coding
description:
  S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.


ensembl_gene_id: SCAB_75321
symbol: priA-2
gene_biotype: protein_coding
description:
  Putative primosomal protein n; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.


ensembl_gene_id: SCAB_75341
symbol: fmt
gene_biotype: protein_coding
description:
  methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.


ensembl_gene_id: SCAB_75351
symbol: CBG74514.1
gene_biotype: protein_coding
description:
  Putative RNA-binding Sun protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.


ensembl_gene_id: SCAB_75371
symbol: rpe
gene_biotype: protein_coding
description:
  Ribulose-phosphate 3-epimerase; PMID:16751529; Belongs to the ribulose-phosphate 3-epimerase family.


ensembl_gene_id: SCAB_75621
symbol: ribAB
gene_biotype: protein_coding
description:
  Riboflavin biosynthesis protein RibA/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.


ensembl_gene_id: SCAB_75631
symbol: ribH
gene_biotype: protein_coding
description:
  6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.


ensembl_gene_id: SCAB_75651
symbol: hisG
gene_biotype: protein_coding
description:
  ATP phosphoribosyltransferase (EC 2.4.2.17); Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily.


ensembl_gene_id: SCAB_75761
symbol: CBG74552.1
gene_biotype: protein_coding
description:
  Putative chitinase/cellulase; PMID: 11315108; PMID: 8515228; cluster 0608 with SCAB28731 but this CDS lacks secretion signal; Belongs to the glycosyl hydrolase 18 family.


ensembl_gene_id: SCAB_7581
symbol: hemC
gene_biotype: protein_coding
description:
  Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.


ensembl_gene_id: SCAB_75841
symbol: rbpA-2
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.


ensembl_gene_id: SCAB_75981
symbol: pxpA
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.


ensembl_gene_id: SCAB_76201
symbol: CBG74595.1
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).


ensembl_gene_id: SCAB_76221
symbol: CBG74597.1
gene_biotype: protein_coding
description:
  putativeCDP-diacylglycerol--glycerol-3-phosphat e3-phosphatidyl-transferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: SCAB_76311
symbol: dinB
gene_biotype: protein_coding
description:
  Putative DNA damage inducible protein; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.


ensembl_gene_id: SCAB_76331
symbol: gcvP
gene_biotype: protein_coding
description:
  Putative glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.


ensembl_gene_id: SCAB_76571
symbol: ung
gene_biotype: protein_coding
description:
  uracil-DNA glycosylase (EC 3.2.2.-); Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.


ensembl_gene_id: SCAB_76621
symbol: lnt
gene_biotype: protein_coding
description:
  Putative lipoprotein N-acyltransferase (integral membrane); Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily.


ensembl_gene_id: SCAB_76721
symbol: SCAB_76721
gene_biotype: protein_coding
description:
  Bacitracin resistance family protein (fragment); Region of similarity proposed syntenous with S. turgidiscabies pathogenicity island.


ensembl_gene_id: SCAB_76891
symbol: CBG74661.1
gene_biotype: protein_coding
description:
  Putative DNA-binding protein; PMID:16511823; PMID:10788377; TTA-Leu codon(s) 138 may indicate regulation by BldA.


ensembl_gene_id: SCAB_77021
symbol: CBG74673.1
gene_biotype: protein_coding
description:
  Putative short-chain dehydrogenase/reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: SCAB_77071
symbol: CBG74678.1
gene_biotype: protein_coding
description:
  Putative transposase; PMID:15686551; PMID:2555783; PMID:16699579; PMID:1700062; PMID:16632251; see also SCAB14321, SCAB21921, SCAB33271; 99% identity with transposase on S. turgidiscabies PAI; TTA-Leu codon(s) 120 may indicate regulation by BldA.


ensembl_gene_id: SCAB_77121
symbol: CBG74682.1
gene_biotype: protein_coding
description:
  Hypothetical protein; No significant db matches; TTA-Leu codon(s) 45 may indicate regulation by BldA.


ensembl_gene_id: SCAB_77311
symbol: CBG74700.1
gene_biotype: protein_coding
description:
  Putative glycosyl hydrolase; PMID:16255248; PMID:8055926; strong match to S. turgidiscabies pathogenicity island.


ensembl_gene_id: SCAB_77331
symbol: CBG74702.1
gene_biotype: protein_coding
description:
  Putative LacI-family transcriptional regulator; PMID:PMID:10224066; strong match to S. turgidiscabies pathogenicity island.


ensembl_gene_id: SCAB_77351
symbol: CBG74704.1
gene_biotype: protein_coding
description:
  Putative oxidoreductase; Only PF02826 (NAD-binding part of 2-hydroxyacid dehd.) not substrate-binding domain of that protein hence not annotated as 2-hydroxyacid-family dehydrogenase.


ensembl_gene_id: SCAB_77591
symbol: CBG74726.1
gene_biotype: protein_coding
description:
  Putative IS transposase; PMID:10809688; PMID:3010046; see also SCAB14691; TTA-Leu codon(s) 114, 125 may indicate regulation by BldA.


ensembl_gene_id: SCAB_77601
symbol: uppP
gene_biotype: protein_coding
description:
  Putative undecaprenyl-diphosphatase 2 (EC 3.6.1.27) (confers bacitracin resistance); Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.


ensembl_gene_id: SCAB_77661
symbol: tuf3
gene_biotype: protein_coding
description:
  Elongation factor TU-3; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.


ensembl_gene_id: SCAB_77721
symbol: CBG74738.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Some have siderophore-binding protein but I can't find an evidence trail for it.


ensembl_gene_id: SCAB_77861
symbol: sbcD
gene_biotype: protein_coding
description:
  Putative exonuclease; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.


ensembl_gene_id: SCAB_78211
symbol: bioD
gene_biotype: protein_coding
description:
  Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.


ensembl_gene_id: SCAB_78221
symbol: bioA
gene_biotype: protein_coding
description:
  Adenosylmethionine-8-amino-7-oxononanoateaminot ra nsferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.


ensembl_gene_id: SCAB_78231
symbol: bioB
gene_biotype: protein_coding
description:
  Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.


ensembl_gene_id: SCAB_78261
symbol: CBG74791.1
gene_biotype: protein_coding
description:
  Putative DNA-binding protein; Codon 70 TTA_Leu (rare) indicates regulation by availability of BldA; TTA-Leu codon(s) 70 may indicate regulation by BldA.


ensembl_gene_id: SCAB_78401
symbol: ureF
gene_biotype: protein_coding
description:
  Urease accessroy protein; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.


ensembl_gene_id: SCAB_78411
symbol: ureG
gene_biotype: protein_coding
description:
  Urease accessory protein; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.


ensembl_gene_id: SCAB_78421
symbol: ureD
gene_biotype: protein_coding
description:
  Urease accessory protein; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.


ensembl_gene_id: SCAB_78471
symbol: rocD
gene_biotype: protein_coding
description:
  Ornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: SCAB_78681
symbol: lig
gene_biotype: protein_coding
description:
  Putative DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.


ensembl_gene_id: SCAB_78761
symbol: CBG74840.1
gene_biotype: protein_coding
description:
  Putative secreted protein; Uncharacterised protein, same transcription unit as pectinesterase, further investigation if pathogenicity associated.


ensembl_gene_id: SCAB_78931
symbol: CBG74857.1
gene_biotype: protein_coding
description:
  Putative secreted esterase; Cutinase genes associated with pathogenicity in some organisms but no characterised similar gene found to support PF01083 on this cds.


ensembl_gene_id: SCAB_78951
symbol: CBG74859.1
gene_biotype: protein_coding
description:
  Putative sugar/fatty acid transferase; PMID:8250904; PMID:12740729; similar to mycobacterial antigen; note twin arginine secretion signal; similar to trehalose corynomycolyl transferase.


ensembl_gene_id: SCAB_78981
symbol: pccB-2
gene_biotype: protein_coding
description:
  Putative propionyl-CoA carboxylase complex B subunit; PMID:15518551; PMID:10589718; PMID:16305230; proposed to carboxylate propionyl coA to generate methylmalonyl coA.


ensembl_gene_id: SCAB_79111
symbol: CBG74874.1
gene_biotype: protein_coding
description:
  Putative ABC transport system transmembrane component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: SCAB_79151
symbol: CBG74877.1
gene_biotype: protein_coding
description:
  Putative oxidoreductase; PMID:15797213; PMID:8169198; PMID:15686551; similar gene poss involved in fasciation in Rhodococcus fascians, similar to gene in S. turgidiscabies PAI.


ensembl_gene_id: SCAB_79171
symbol: rarA4
gene_biotype: protein_coding
description:
  RarA (conservon) homologue; PMID: 12657469; cluster 0205 with SCAB20261 and SCAB32081; similarity to conservon gene implicated in aerial mycelium formation see PMID:12657469; conservon; TTA-Leu codon(s) 34 may indicate regulation by BldA.


ensembl_gene_id: SCAB_79211
symbol: rarE4
gene_biotype: protein_coding
description:
  RarE (conservon) homologue; PMID: 12657469; PMID:15111132; conservon; Belongs to the cytochrome P450 family.


ensembl_gene_id: SCAB_79311
symbol: CBG74891.1
gene_biotype: protein_coding
description:
  Putative aminotransferase (fragment); Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: SCAB_79361
symbol: CBG74896.1
gene_biotype: protein_coding
description:
  Putative BIFUNCTIONAL ENZYME MBTA: SALICYL-AMP LIGASE (SAL-AMP LIGASE) + SALICYL-S-ArCP SYNTHETASE; TTA-Leu codon(s) 7 may indicate regulation by BldA.


ensembl_gene_id: SCAB_79431
symbol: CBG74903.1
gene_biotype: protein_coding
description:
  Putative sugar ABC transport system, ATP-binding protein; TTA-Leu codon(s) 144 may indicate regulation by BldA.


ensembl_gene_id: SCAB_79441
symbol: CBG74904.1
gene_biotype: protein_coding
description:
  Putative ABC ribose transport system, permease protein; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: SCAB_79451
symbol: CBG74905.1
gene_biotype: protein_coding
description:
  Putative ribose transport system permease protein RbsC; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: SCAB_79561
symbol: CBG74916.1
gene_biotype: protein_coding
description:
  Putative secreted glycosyl hydrolase; PMID:14761997; Belongs to the glycosyl hydrolase 5 (cellulase A) family.


ensembl_gene_id: SCAB_79591
symbol: CBG74919.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; PMID:14652074; PMID:15563836; PMID:10873841; TTA-Leu codon(s) 81 may indicate regulation by BldA; perhaps involved with neighbouring gene cluster.


ensembl_gene_id: SCAB_79601
symbol: CBG74920.1
gene_biotype: protein_coding
description:
  Putative acyl carrier protein; PMID:10099135; PMID:8996103; nearest match synthesis of coronafacic acid, pathogenicity-involved.


ensembl_gene_id: SCAB_79621
symbol: CBG74922.1
gene_biotype: protein_coding
description:
  Putative polyketide KS component; TTA-Leu codon(s) 332 may indicate regulation by BldA; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: SCAB_79661
symbol: CBG74926.1
gene_biotype: protein_coding
description:
  Putative polyketide synthase; PMID:16207901; PMID:11358695; PMID:9860992; PMID:14736915; many more matches.


ensembl_gene_id: SCAB_79801
symbol: gpsA
gene_biotype: protein_coding
description:
  Putative glycerol-3-phosphate dehydrogenase; Cluster 0583 with SCAB26541; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.


ensembl_gene_id: SCAB_80081
symbol: CBG74969.1
gene_biotype: protein_coding
description:
  Putative sodium:dicarboxylate transport protein; Cluster 0604 with SCAB28061; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: SCAB_80111
symbol: mltG-2
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.


ensembl_gene_id: SCAB_80171
symbol: CBG74978.1
gene_biotype: protein_coding
description:
  Germicidin synthase: homolog to SCO7221; alignment with S. avermitilis indictaed pseudogene SCAB80172.


ensembl_gene_id: SCAB_80271
symbol: CBG74989.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Possibly transposase fragment by similarity (no Pfam); TTA-Leu codon(s) 59 may indicate regulation by BldA.


ensembl_gene_id: SCAB_80491
symbol: CBG75011.1
gene_biotype: protein_coding
description:
  Putative branched-chain amino acid transport system, permease protein; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: SCAB_80621
symbol: CBG75023.1
gene_biotype: protein_coding
description:
  Putative membrane protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: SCAB_81311
symbol: CBG75092.1
gene_biotype: protein_coding
description:
  Putative transposase; PMID:8973350; PMID: 9862476; PMID:7518087; see also SCAB0831, SCAB1341, SCAB10021.


ensembl_gene_id: SCAB_81351
symbol: CBG75096.1
gene_biotype: protein_coding
description:
  Putative membrane protein; PMID:16597959; PMID:16592952; contains repeats PF00805; TTA-Leu codon(s) 370 may indicate regulation by BldA.


ensembl_gene_id: SCAB_81851
symbol: CBG75141.1
gene_biotype: protein_coding
description:
  Putative PROBABLE SERINE/THREONINE-PROTEIN KINASE TRANSCRIPTIONAL REGULATORY PROTEIN PKNK (PROTEIN KINASE K) (STPK K).


ensembl_gene_id: SCAB_81861
symbol: CBG75142.1
gene_biotype: protein_coding
description:
  Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.


ensembl_gene_id: SCAB_81931
symbol: CBG75149.1
gene_biotype: protein_coding
description:
  Putative muconate cycloisomerase; Belongs to the mandelate racemase/muconate lactonizing enzyme family.


ensembl_gene_id: SCAB_82261
symbol: paaK
gene_biotype: protein_coding
description:
  phenylacetate-CoA ligase; Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).


ensembl_gene_id: SCAB_82381
symbol: ung-2
gene_biotype: protein_coding
description:
  Uracil DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.


ensembl_gene_id: SCAB_82901
symbol: rlmG
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.


ensembl_gene_id: SCAB_83111
symbol: lnt-2
gene_biotype: protein_coding
description:
  Putative transferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily.


ensembl_gene_id: SCAB_83281
symbol: CBG75281.1
gene_biotype: protein_coding
description:
  Putative glyceraldehyde-3-phosphate dehydrogenase; Cluster 0095 with SCAB4751, SCAB10521, SCAB69701; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.


ensembl_gene_id: SCAB_83371
symbol: pep2B
gene_biotype: protein_coding
description:
  Conserved hypothetical Pep2B protein; PMID:10821190; cluster 0601 with SCAB28001; PMID:10821190 in S. coelicolor, clusters of pep1-treS-pep2-glgB genes; glgB involved in aerial mycelium development.


ensembl_gene_id: SCAB_83381
symbol: treSB
gene_biotype: protein_coding
description:
  Putative alpha amylase; PMID:15378530; PMID:10821190; PMID:10821190 in S. coelicolor, clusters of pep1-treS-pep2-glgB genes; glgB involved in aerial mycelium development.


ensembl_gene_id: SCAB_83521
symbol: crcB
gene_biotype: protein_coding
description:
  Putative integral membrane protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.


ensembl_gene_id: SCAB_83541
symbol: uppP-2
gene_biotype: protein_coding
description:
  Putative transport integral membrane protein; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.


ensembl_gene_id: SCAB_83621
symbol: rho-2
gene_biotype: protein_coding
description:
  Putative transcription terminator factor (fragment); Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.


ensembl_gene_id: SCAB_83841
symbol: CBG75335.1
gene_biotype: protein_coding
description:
  Putative regulator; PMID:15328113; PMID:16085885; PMID:9831532; PMID:16207901; PMID:12940979; Similar putative regulators found in many antibiotic production clusters. Several subthreshold TPR hits; TTA-Leu codon(s) 13, 286, 353, 789 may indicate regulation by BldA.


ensembl_gene_id: SCAB_83861
symbol: SCAB_83861
gene_biotype: protein_coding
description:
  Conserved hypothetical protein (fragment); PMID:16207901; pseudo: frameshifts after codon 43, 106, 180; and deletion - match breaks off codon 87 resumes codon 115.


ensembl_gene_id: SCAB_83891
symbol: CBG75339.1
gene_biotype: protein_coding
description:
  Putative type I polyketide synthase; PMID:16207901; PMID:16085885; PMID:11094342; PMID:14652074; PMID:10873841; PMID:16806745; TTA-Leu codon(s) 962 may indicate regulation by BldA.


ensembl_gene_id: SCAB_83991
symbol: CBG75349.1
gene_biotype: protein_coding
description:
  Putative NDP-hexose 2,3-dehydratase; PMID:16207901; PMID:12115055; PMID:15271354; PMID:8668120; PMID:11358695.


ensembl_gene_id: SCAB_8401
symbol: SCAB_8401
gene_biotype: protein_coding
description:
  Putative para-aminonezoic acid synthase; PMID:8472854; PMID:1178249; PMID:9044253; PMID:14700630; TTA-Leu codon(s) 459 may indicate regulation by BldA.


ensembl_gene_id: SCAB_84011
symbol: CBG75351.1
gene_biotype: protein_coding
description:
  Putative NDP-hexose 4-ketoreductase; PMID:16207901; PMID:9933932; PMID:11094336; PMID:12770825; many more matches.


ensembl_gene_id: SCAB_84031
symbol: CBG75353.1
gene_biotype: protein_coding
description:
  Putative dTDP-glucose synthase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.


ensembl_gene_id: SCAB_84041
symbol: CBG75354.1
gene_biotype: protein_coding
description:
  Putative dTDP-glucose 4,6-dehydratase; PMID:16207901; PMID:12770825; PMID:16632249; PMID:10770761; polyketide sugar unit biosynthesis?; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.


ensembl_gene_id: SCAB_84071
symbol: CBG75357.1
gene_biotype: protein_coding
description:
  Putative thioesterase; PMID:16207901; PMID:10954087; PMID:9512878; PMID:12940979; PMID:16723571; PMID:11782498; PMID:15563826; PMID:14652074.


ensembl_gene_id: SCAB_84091
symbol: CBG75359.1
gene_biotype: protein_coding
description:
  Putative phosphopantetheinyl transferase; PMID:16207901; PMID:14695521; PMID:21344786; see also SCAB15441, SCAB15451; Belongs to the P-Pant transferase superfamily.


ensembl_gene_id: SCAB_84101
symbol: CBG75360.1
gene_biotype: protein_coding
description:
  Putative AfsR-type regulatory protein; PMID:16207901; PMID: 91071605; PMID:12822997; PMID:10517581; TTA-Leu codon(s) 50 may indicate regulation by BldA.


ensembl_gene_id: SCAB_84271
symbol: CBG75375.1
gene_biotype: protein_coding
description:
  Putative ABC transport system integral membrane component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: SCAB_84371
symbol: cbiO
gene_biotype: protein_coding
description:
  Cobalt transport system ATP binding component; Part of an ABC transporter complex. Responsible for energy coupling to the transport system.


ensembl_gene_id: SCAB_84391
symbol: cbiN
gene_biotype: protein_coding
description:
  Puative cobalt transport protein; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import; Belongs to the CbiN family.


ensembl_gene_id: SCAB_84401
symbol: cbiM
gene_biotype: protein_coding
description:
  Putative cobalt transport system integral membrane component; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.


ensembl_gene_id: SCAB_84421
symbol: CBG75388.1
gene_biotype: protein_coding
description:
  Putative high-affinity nickel-chelating protein; PMID:7896709; Belongs to the NiCoT transporter (TC 2.A.52) family.


ensembl_gene_id: SCAB_84601
symbol: grpE-2
gene_biotype: protein_coding
description:
  Putative GrpE heat shock protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several round [...]


ensembl_gene_id: SCAB_84631
symbol: clpB-2
gene_biotype: protein_coding
description:
  Chaperone; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.


ensembl_gene_id: SCAB_84861
symbol: CBG75433.1
gene_biotype: protein_coding
description:
  Putative secreted amidase; PMID:15870355; similar protein queches quorum-sensing homoserine lactone signal.


ensembl_gene_id: SCAB_84981
symbol: CBG75445.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Codon 110 TTA-Leu (bldA); homologs in S. coelicolor and S. avermitilis also have TTA; TTA-Leu codon(s) 110 may indicate regulation by BldA.


ensembl_gene_id: SCAB_85001
symbol: CBG75447.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Cluster 0884 with SCAB87091; TTA-Leu codon(s) 62 may indicate regulation by BldA.


ensembl_gene_id: SCAB_85121
symbol: CBG75457.1
gene_biotype: protein_coding
description:
  Putative sigma factor; Cluster 0758 with SCAB5471; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: SCAB_85431
symbol: CBG75488.1
gene_biotype: protein_coding
description:
  Putative ABC transport system integral membrane component; PMID:9721311; PMID:15870461; maybe siderophore uptake system.


ensembl_gene_id: SCAB_85441
symbol: CBG75489.1
gene_biotype: protein_coding
description:
  Putative ABC-transport system ATP-binding component; PMID:9720878; PMID:15870461; maybe siderophore uptake system.


ensembl_gene_id: SCAB_85451
symbol: CBG75490.1
gene_biotype: protein_coding
description:
  Putative secreted siderophore-binding lipoprotein (transport system associated); Maybe siderophore transport system.


ensembl_gene_id: SCAB_85481
symbol: CBG75493.1
gene_biotype: protein_coding
description:
  Putative siderophore transport system integral membrane component, FecCD family; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: SCAB_85581
symbol: clpP
gene_biotype: protein_coding
description:
  Putative ATP-dependent Clp protease proteolytic subunit 2; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.


ensembl_gene_id: SCAB_85591
symbol: clpP-2
gene_biotype: protein_coding
description:
  Putative ATP-dependent Clp protease proteolytic subunit 1; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.


ensembl_gene_id: SCAB_85681
symbol: melC2B
gene_biotype: protein_coding
description:
  Putative tyrosinase (monophenol monooxygenase, melanin production catalyst); PMID:3932128; PMID:3002431.


ensembl_gene_id: SCAB_85801
symbol: mraY
gene_biotype: protein_coding
description:
  phospho-N-acetylmuramoyl-pentapeptide-transfera se; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.


ensembl_gene_id: SCAB_86041
symbol: CBG75546.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.


ensembl_gene_id: SCAB_86511
symbol: CBG75592.1
gene_biotype: protein_coding
description:
  Putative oligopeptide transport system (integral membrane and ATP-binding proteins); Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: SCAB_86761
symbol: metA
gene_biotype: protein_coding
description:
  Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.


ensembl_gene_id: SCAB_86971
symbol: hypA
gene_biotype: protein_coding
description:
  Putative hydrogenase nickel incorporation protein; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.


ensembl_gene_id: SCAB_87291
symbol: CBG75668.1
gene_biotype: protein_coding
description:
  Putative transposase; PMID:16208464; cluster 0050 6: SCAB16641, SCAB24431, SCAB30541, SCAB30831, SCAB68821, SCAB87291.


ensembl_gene_id: SCAB_87301
symbol: CBG75669.1
gene_biotype: protein_coding
description:
  Putative transposase; PMID:16208464; PMID:14702401; cluster 0034: SCAB14601, SCAB16631, SCAB24421, SCAB30531, SCAB30841, SCAB68821, SCAB87301.


ensembl_gene_id: SCAB_87641
symbol: rnj-2
gene_biotype: protein_coding
description:
  Putative hydrolase (metallo-beta-lactamase superfamily); An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.


ensembl_gene_id: SCAB_87711
symbol: hisC2
gene_biotype: protein_coding
description:
  Putative phenylalanine aminotransferase; May catalyze the transamination reaction in phenylalanine biosynthesis; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: SCAB_87741
symbol: pdhA
gene_biotype: protein_coding
description:
  PROBABLE PYRUVATE DEHYDROGENASE E1 COMPONENT (ALPHA SUBUNIT) PDHA (PYRUVATE DECARBOXYLASE) (PYRUVATE DEHYDROGENASE) (PYRUVIC DEHYDROGENASE).


ensembl_gene_id: SCAB_87751
symbol: pdhB
gene_biotype: protein_coding
description:
  PROBABLE PYRUVATE DEHYDROGENASE E1 COMPONENT (BETA SUBUNIT) PDHB (PYRUVATE DECARBOXYLASE) (PYRUVATE DEHYDROGENASE) (PYRUVIC DEHYDROGENASE).


ensembl_gene_id: SCAB_8781
symbol: SCAB_8781
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; PMID:12107139; PMID:10627032; Belongs to the anti-sigma-factor antagonist family.


ensembl_gene_id: SCAB_88241
symbol: infA-2
gene_biotype: protein_coding
description:
  Putative PROBABLE TRANSLATION INITIATION FACTOR IF-1 INFA; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.


ensembl_gene_id: SCAB_88461
symbol: pntB
gene_biotype: protein_coding
description:
  NAD(P) transhydrogenase beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.


ensembl_gene_id: SCAB_88651
symbol: CBG75801.1
gene_biotype: protein_coding
description:
  Putative phenazine antibiotic biosynthesis protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: SCAB_88961
symbol: CBG75831.1
gene_biotype: protein_coding
description:
  Putative LysR family transcriptional regulator; PMID: 7574650; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: SCAB_89241
symbol: CBG75859.1
gene_biotype: protein_coding
description:
  Hypothetical protein; No significant db matches; TTA-Leu codon(s) 77 may indicate regulation by BldA.


ensembl_gene_id: SCAB_89361
symbol: CBG75871.1
gene_biotype: protein_coding
description:
  Putative dihydrodipicolinate synthetase; Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate. Belongs to the DapA family.


ensembl_gene_id: SCAB_89801
symbol: cysK2
gene_biotype: protein_coding
description:
  S-sulfo-L-cysteine synthase (3-phospho-L-serine-dependent); POSSIBLE CYSTEINE SYNTHASE A CYSK2 (O-ACETYLSERINE SULFHYDRYLASE) (O-ACETYLSERINE (THIOL)-LYASE) (CSASE).


ensembl_gene_id: SCAB_89821
symbol: CBG75915.1
gene_biotype: protein_coding
description:
  Putative integral membrane protein; No significant db matches; TTA-Leu codon(s) 75 may indicate regulation by BldA.


ensembl_gene_id: SCAB_89971
symbol: CBG75931.1
gene_biotype: protein_coding
description:
  Putative amino acid ABC transporter solute-binding protein; Belongs to the bacterial solute-binding protein 3 family.


ensembl_gene_id: SCAB_90021
symbol: CBG75936.1
gene_biotype: protein_coding
description:
  5.1.4; PMID:1847988; PMID:11985710; PMID:9245803; PMID:16952952; see also SCAB10801; TTA-Leu codon(s) 31 may indicate regulation by BldA.


ensembl_gene_id: SCAB_9011
symbol: SCAB_9011
gene_biotype: protein_coding
description:
  Ptative permease component of ABC transporter; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: SCAB_90161
symbol: CBG75951.1
gene_biotype: protein_coding
description:
  Putative PROBABLE SHORT-CHAIN TYPE DEHYDROGENASE; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: SCAB_90181
symbol: CBG75953.1
gene_biotype: protein_coding
description:
  Putative TetR-family transcriptional regulator; No obvious secondary metabolite cluster: transferred annotation possibly misleading.


ensembl_gene_id: SCAB_90461
symbol: CBG75979.1
gene_biotype: protein_coding
description:
  Putative glycosyltransferase (maybe sortase substrate); PMID: 16299590; S. coelicolor homolog identified as stealth family protein, maybe involved in pathogenicity; codon 401-405 LAATA which may be close enough to S. coelicolor sortase signal LAxTG for sortase recognition.


ensembl_gene_id: SCAB_90541
symbol: CBG75985.1
gene_biotype: protein_coding
description:
  Putative LysR-family transcriptional regulator; PMID:11700358; PMID:8419293; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: SCAB_90701
symbol: CBG76001.1
gene_biotype: protein_coding
description:
  Putative P450 monooxygenase; PMID: 12822997; PMID:11212921; PMID:11673424; PMID:12177738; Belongs to the cytochrome P450 family.


ensembl_gene_id: SCAB_90821
symbol: CBG76014.1
gene_biotype: protein_coding
description:
  Putative IS transposase; PMID:1332944; overlaps, seems to be common pattern see also SCAB0371, SCAB0691, SCAB0991, SCAB23721, SCAB42901; TTA-Leu codon(s) 4 may indicate regulation by BldA.


ensembl_gene_id: SCAB_91001
symbol: CBG76032.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; PMID: 6318753; nearest match sequenced as part of S. hygroscopicus hygromycin B biosynthesis cluster; cluster 0311 with SCAB0071.


ensembl_gene_id: SCAB_91011
symbol: CBG76033.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; PMID:12618462; PMID:16252836; cluster 0310 with SCAB0061; SCAB91021 and SCAB91031 also have similarity to A. nicotinovorans plasmid; TTA-Leu codon(s) 5 248 may indicate regulation by BldA.


ensembl_gene_id: SCAB_91021
symbol: CBG76034.1
gene_biotype: protein_coding
description:
  0.0.1; PMID:12618462; PMID:12923100; cluster 0309 with SCAB0051; SCAB91011 and SCAB91031 also have similarity to A. nicotinovorans plasmid.


ensembl_gene_id: SCAB_91031
symbol: CBG76035.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; PMID:12618462; contains two putative coiled-coil regions; cluster 0308 with SCAB0041; match to A. nicotinovorans plasmid not significant but circumstantial evidence - SCAB91021, SCAB91011 also hit same sequence.


ensembl_gene_id: SCAB_91041
symbol: ttrA2
gene_biotype: protein_coding
description:
  Putative helicase-like protein; PMID:12127493; PMID:10784050; cluster 0307 with SCAB0031; many more matches amongst Streptomyces genus.


ensembl_gene_id: SCAB_9161
symbol: SCAB_9161
gene_biotype: protein_coding
description:
  Putative anti-anti-sigma-factor; TTA-Leu codon(s) 127 may indicate regulation by BldA; Belongs to the anti-sigma-factor antagonist family.


ensembl_gene_id: SCAB_9411
symbol: SCAB_9411
gene_biotype: protein_coding
description:
  Putative ABC transporter permease; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: SCAB_9431
symbol: rbsA
gene_biotype: protein_coding
description:
  Putative ABC transporter ATP-binding protein; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family.


ensembl_gene_id: SCAB_9531
symbol: cpeB
gene_biotype: protein_coding
description:
  Catalase/peroxidase; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily.


ensembl_gene_id: SCAB_9601
symbol: iolG
gene_biotype: protein_coding
description:
  Putative oxidoreductase; Involved in the oxidation of myo-inositol (MI) to 2-keto-myo- inositol (2KMI or 2-inosose).


ensembl_gene_id: SCAB_9701
symbol: hpaE
gene_biotype: protein_coding
description:
  5-carboxy-2-hydroxymuconate semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: SCAB_9801
symbol: cobI
gene_biotype: protein_coding
description:
  Precorrin-2 C20-methyltransferase / precorrin-3B C17-methyltransferase; Probable bifunctional protein, CobI-CobJ fusion protein: S-adenosyl-L-methionine-precorrin-2 methyl transferase + precorrin-3 methylase.


ensembl_gene_id: SCAB_9821
symbol: cbiD
gene_biotype: protein_coding
description:
  Putative cobalamin biosynthesis-related protein; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.


ensembl_gene_id: SCAB_9851
symbol: SCAB_9851
gene_biotype: protein_coding
description:
  Putative FecCD-family membrane transport protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


