# pathwayInfo

id: SM00929
description: NADH-ubiquinone oxidoreductase-G iron-sulfur binding region
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00929
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM00929_NADH-ubiquinone_oxidoreductase-G_iron-sulfur_binding_region


id: SM00934
description: Orotidine 5-phosphate decarboxylase / HUMPS family
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00934
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM00934_Orotidine_5-phosphate_decarboxylase_/_HUMPS_family


id: SM00937
description: This domain is found in peptide chain release factors.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00937
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM00937_This_domain_is_found_in_peptide_chain_release_factors.


id: SM00948
description: Proteasome subunit A N-terminal signature Add an annotation
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00948
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM00948_Proteasome_subunit_A_N-terminal_signature__Add_an_annotation


id: SM00949
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00949
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM00949_This_domain_is_named_PAZ_after_the_proteins_Piwi_Argonaut_and_Zwille._This_domain_is_found_in_two_families_of_proteins_that_are_involved_in_post-transcriptional_gene_silencing._These_are_the_Piwi_family_and_the_Dicer_family,_that_includes_the_Carpel_...

description:
  This domain is named PAZ after the proteins Piwi Argonaut and Zwille. This domain is found in two families of proteins that are involved in post-transcriptional gene silencing. These are the Piwi family and the Dicer family, that includes the Carpel ...


id: SM00950
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00950
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM00950_This_domain_is_found_in_the_protein_Piwi_and_its_relatives._The_function_of_this_domain_is_the_dsRNA_guided_hydrolysis_of_ssRNA._Determination_of_the_crystal_structure_of_Argonaute_reveals_that_PIWI_is_an_RNase_H_domain,_and_identifies_Argonaute_as_...

description:
  This domain is found in the protein Piwi and its relatives. The function of this domain is the dsRNA guided hydrolysis of ssRNA. Determination of the crystal structure of Argonaute reveals that PIWI is an RNase H domain, and identifies Argonaute as ...


id: SM00951
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00951
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM00951_QLQ_is_named_after_the_conserved_Gln,_Leu,_Gln_motif._QLQ_is_found_at_the_N-terminus_of_SWI2/SNF2_protein,_which_has_been_shown_to_be_involved_in_protein-protein_interactions._QLQ_has_been_postulated_to_be_involved_in_mediating_protein_interactions_...

description:
  QLQ is named after the conserved Gln, Leu, Gln motif. QLQ is found at the N-terminus of SWI2/SNF2 protein, which has been shown to be involved in protein-protein interactions. QLQ has been postulated to be involved in mediating protein interactions ...


id: SM00952
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00952
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM00952_This_domain_is_found_in_various_eukaryotic_species,_particularly_in_apicomplexans_such_as_Plasmodium_falciparum,_where_it_is_found_in_proteins_that_are_important_in_various_parasite-host_cell_interactions._It_is_thought_to_be_an_RNA-binding_domain_...

description:
  This domain is found in various eukaryotic species, particularly in apicomplexans such as Plasmodium falciparum, where it is found in proteins that are important in various parasite-host cell interactions. It is thought to be an RNA-binding domain ...


id: SM00955
description: This domain is the catalytic domain of ribonuclease II.PUBMED:16806266
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00955
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM00955_This_domain_is_the_catalytic_domain_of_ribonuclease_II.PUBMED:16806266


id: SM00956
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00956
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM00956_This_DNA-binding_domain_is_found_in_the_RecQ_helicase_among_others_and_has_a_helix-turn-helix_structure._The_RQC_domain,_found_only_in_RecQ_family_enzymes,_is_a_high_affinity_G4_DNA_binding_domain_PUBMED:16530788.

description:
  This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure. The RQC domain, found only in RecQ family enzymes, is a high affinity G4 DNA binding domain PUBMED:16530788.


id: SM00963
description: SRP54-type protein, helical bundle domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00963
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM00963_SRP54-type_protein,_helical_bundle_domain


id: SM00964
description: STAT protein, protein interaction domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00964
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM00964_STAT_protein,_protein_interaction_domain


id: SM00967
description: RNA 2-O ribose methyltransferase substrate binding
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00967
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM00967_RNA_2-O_ribose_methyltransferase_substrate_binding


id: SM00969
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00969
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM00969_The_SOCS_box_acts_as_a_bridge_between_specific_substrate-_binding_domains_and_more_generic_proteins_that_comprise_a_large_family_of_E3_ubiquitin_protein_ligases.

description:
[cell repeats an earlier one in this file: 161 characters]


id: SM00975
description: Telomerase ribonucleoprotein complex - RNA binding domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00975
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM00975_Telomerase_ribonucleoprotein_complex_-_RNA_binding_domain


id: SM00976
description: Telomeric single stranded DNA binding POT1/CDC13
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00976
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM00976_Telomeric_single_stranded_DNA_binding_POT1/CDC13


id: SM00978
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00978
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM00978_Tim44_is_an_essential_component_of_the_machinery_that_mediates_the_translocation_of_nuclear-encoded_proteins_across_the_mitochondrial_inner_membrane_PUBMED:10430866._Tim44_is_thought_to_bind_phospholipids_of_the_mitochondrial_inner_membrane_both_by_...

description:
  Tim44 is an essential component of the machinery that mediates the translocation of nuclear-encoded proteins across the mitochondrial inner membrane PUBMED:10430866. Tim44 is thought to bind phospholipids of the mitochondrial inner membrane both by ...


id: SM00981
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00981
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM00981_The_THUMP_domain_is_named_after_after_thiouridine_synthases,_methylases_and_PSUSs_PUBMED:11295541._The_THUMP_domain_consists_of_about_110_amino_acid_residues._The_structure_of_ThiI_reveals_that_the_THUMP_has_a_fold_unlike_that_of_previously_...

description:
  The THUMP domain is named after after thiouridine synthases, methylases and PSUSs PUBMED:11295541. The THUMP domain consists of about 110 amino acid residues. The structure of ThiI reveals that the THUMP has a fold unlike that of previously ...


id: SM00983
description: Thiamin pyrophosphokinase, vitamin B1 binding domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00983
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM00983_Thiamin_pyrophosphokinase,_vitamin_B1_binding_domain


id: SM00985
description: Ubiquitin-activating enzyme e1 C-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00985
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM00985_Ubiquitin-activating_enzyme_e1_C-terminal_domain


id: SM00987
description: UreE urease accessory protein, C-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00987
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM00987_UreE_urease_accessory_protein,_C-terminal_domain


id: SM00990
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00990
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM00990_This_entry_contains_proteins_with_the_VRR-NUC_domain._It_is_associated_with_members_of_the_PD-(D/E)XK_nuclease_superfamily,_which_include_the_type_III_restriction_modification_enzymes,_for_example_StyLTI.

description:
  This entry contains proteins with the VRR-NUC domain. It is associated with members of the PD-(D/E)XK nuclease superfamily, which include the type III restriction modification enzymes, for example StyLTI.


id: SM00991
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00991
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM00991_A_conserved_domain_of_46_amino_acids,_called_WHEP-TRS_has_been_shown_PUBMED:1756734_to_exist_in_a_number_of_higher_eukaryote_aminoacyl-transfer_RNA_synthetases._This_domain_is_present_one_to_six_times_in_the_several_enzymes._There_are_three_copies_in_...

description:
  A conserved domain of 46 amino acids, called WHEP-TRS has been shown PUBMED:1756734 to exist in a number of higher eukaryote aminoacyl-transfer RNA synthetases. This domain is present one to six times in the several enzymes. There are three copies in ...


id: SM00992
description: Hemimethylated DNA-binding protein YccV like
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00992
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM00992_Hemimethylated_DNA-binding_protein_YccV_like


id: SM00997
description: S-adenosyl-L-homocysteine hydrolase, NAD binding domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00997
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM00997_S-adenosyl-L-homocysteine_hydrolase,_NAD_binding_domain


id: SM01002
description: Alanine dehydrogenase/PNT, C-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01002
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01002_Alanine_dehydrogenase/PNT,_C-terminal_domain


id: SM01003
description: Alanine dehydrogenase/PNT, N-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01003
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01003_Alanine_dehydrogenase/PNT,_N-terminal_domain


id: SM01007
description: Class II Aldolase and Adducin N-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01007
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01007_Class_II_Aldolase_and_Adducin_N-terminal_domain


id: SM01008
description: Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01008
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01008_Aldehyde_oxidase_and_xanthine_dehydrogenase,_a/b_hammerhead_domain


id: SM01010
description: 5-AMP-activated protein kinase beta subunit, interation domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01010
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01010_5-AMP-activated_protein_kinase_beta_subunit,_interation_domain


id: SM01017
description: Arrestin (or S-antigen), C-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01017
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01017_Arrestin_(or_S-antigen),_C-terminal_domain


id: SM01020
description: Beta2-adaptin appendage, C-terminal sub-domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01020
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01020_Beta2-adaptin_appendage,_C-terminal_sub-domain


id: SM01022
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01022
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01022_The_ASCH_domain_adopts_a_beta-barrel_fold_similar_to_that_of_the_PUA_domain._It_is_thought_to_function_as_an_RNA-binding_domain_during_coactivation,_RNA-processing_and_possibly_during_prokaryotic_translation_regulation_PUBMED:16322048.

description:
  The ASCH domain adopts a beta-barrel fold similar to that of the PUA domain. It is thought to function as an RNA-binding domain during coactivation, RNA-processing and possibly during prokaryotic translation regulation PUBMED:16322048.


id: SM01024
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01024
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01024_This_domain_is_found_at_the_N_terminal_of_the_mitochondrial_ATPase_BSC1._It_encodes_the_import_and_intramitochondrial_sorting_for_the_protein.

description:
  This domain is found at the N terminal of the mitochondrial ATPase BSC1. It encodes the import and intramitochondrial sorting for the protein.


id: SM01025
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01025
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01025_The_BEN_domain_is_found_in_diverse_animal_proteins_such_as_BANP/SMAR1,_NAC1_and_the_Drosophila_mod(mdg4)_isoform_C,_in_the_chordopoxvirus_virosomal_protein_E5R_and_in_several_proteins_of_polydnaviruses._Computational_analysis_suggests_that_the_BEN_...

description:
  The BEN domain is found in diverse animal proteins such as BANP/SMAR1, NAC1 and the Drosophila mod(mdg4) isoform C, in the chordopoxvirus virosomal protein E5R and in several proteins of polydnaviruses. Computational analysis suggests that the BEN ...


id: SM01039
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01039
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01039_The_BRICHOS_domain_is_about_100_amino_acids_long._It_is_found_in_a_variety_of_proteins_implicated_in_dementia,_respiratory_distress_and_cancer._Its_exact_function_is_unknown

description:
  The BRICHOS domain is about 100 amino acids long. It is found in a variety of proteins implicated in dementia, respiratory distress and cancer. Its exact function is unknown


id: SM01050
description: Cactus-binding C-terminus of cactin protein
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01050
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01050_Cactus-binding_C-terminus_of_cactin_protein


id: SM01051
description: Microtubule-binding calmodulin-regulated spectrin-associated
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01051
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01051_Microtubule-binding_calmodulin-regulated_spectrin-associated


id: SM01052
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01052
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01052_Cytoskeleton-associated_proteins_(CAPs)_are_involved_in_the_organisation_of_microtubules_and_transportation_of_vesicles_and_organelles_along_the_cytoskeletal_network._A_conserved_motif,_CAP-Gly,_has_been_identified_in_a_number_of_CAPs,_including_...

description:
  Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including ...


id: SM01060
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01060
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01060_Catalases_are_antioxidant_enzymes_that_catalyse_the_conversion_of_hydrogen_peroxide_to_water_and_molecular_oxygen,_serving_to_protect_cells_from_its_toxic_effects_PUBMED:11351128._Hydrogen_peroxide_is_produced_as_a_consequence_of_oxidative_cellular_...

description:
  Catalases are antioxidant enzymes that catalyse the conversion of hydrogen peroxide to water and molecular oxygen, serving to protect cells from its toxic effects PUBMED:11351128. Hydrogen peroxide is produced as a consequence of oxidative cellular ...


id: SM01072
description: Cell division protein 48 (CDC48) domain 2
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01072
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01072_Cell_division_protein_48_(CDC48)_domain_2


id: SM01073
description: Cell division protein 48 (CDC48) N-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01073
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01073_Cell_division_protein_48_(CDC48)_N-terminal_domain


id: SM01076
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01076
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01076_CG-1_domains_are_highly_conserved_domains_of_about_130_amino-acid_residues_containing_a_predicted_bipartite_NLS_and_named_after_a_partial_cDNA_clone_isolated_from_parsley_encoding_a_sequence-specific_DNA-binding_protein_PUBMED:8075408._CG-1_domains_...

description:
  CG-1 domains are highly conserved domains of about 130 amino-acid residues containing a predicted bipartite NLS and named after a partial cDNA clone isolated from parsley encoding a sequence-specific DNA-binding protein PUBMED:8075408. CG-1 domains ...


id: SM01077
description: Uncharacterized conserved protein CG6151-P
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01077
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01077_Uncharacterized_conserved_protein_CG6151-P


id: SM01083
description: N-terminal domain of CBF1 interacting co-repressor CIR
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01083
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01083_N-terminal_domain_of_CBF1_interacting_co-repressor_CIR


id: SM01084
description: Cyclin-dependent kinase regulatory subunit
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01084
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01084_Cyclin-dependent_kinase_regulatory_subunit


id: SM01086
description: C-terminal, D2-small domain, of ClpB protein
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01086
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01086_C-terminal,_D2-small_domain,_of_ClpB_protein


id: SM01089
description: Gap junction channel protein cysteine-rich domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01089
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01089_Gap_junction_channel_protein_cysteine-rich_domain


id: SM01092
description: CO dehydrogenase flavoprotein C-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01092
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01092_CO_dehydrogenase_flavoprotein_C-terminal_domain


id: SM01096
description: Carbamoyl-phosphate synthetase large chain, oligomerisation domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01096
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01096_Carbamoyl-phosphate_synthetase_large_chain,_oligomerisation_domain


id: SM01097
description: Carbamoyl-phosphate synthase small chain, CPSase domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01097
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01097_Carbamoyl-phosphate_synthase_small_chain,_CPSase_domain


id: SM01104
description: Spt5 C-terminal nonapeptide repeat binding Spt4
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01104
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01104_Spt5_C-terminal_nonapeptide_repeat_binding_Spt4


id: SM01109
description: The CUT domain is a DNA-binding domain often found in combination with a downstream homeodomain.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01109
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01109_The_CUT_domain_is_a_DNA-binding_domain_often_found_in_combination_with_a_downstream_homeodomain.


id: SM01115
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01115
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01115_The_cwf21_family_is_involved_in_mRNA_splicing._It_has_been_isolated_as_a_subcomplex_of_the_splicosome_in_Schizosaccharomyces_pombe_(PUBMED:11884590)._The_function_of_the_cwf21_domain_is_to_bind_directly_to_the_spliceosomal_protein_Prp8._Mutations_in_...

description:
  The cwf21 family is involved in mRNA splicing. It has been isolated as a subcomplex of the splicosome in Schizosaccharomyces pombe (PUBMED:11884590). The function of the cwf21 domain is to bind directly to the spliceosomal protein Prp8. Mutations in ...


id: SM01117
description: Cytochrome b5-like Heme/Steroid binding domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01117
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01117_Cytochrome_b5-like_Heme/Steroid_binding_domain


id: SM01118
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01118
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01118_These_sequences_are_functionally_identified_as_members_of_the_adenylate_cyclase_family,_which_catalyses_the_conversion_of_ATP_to_3,5-cyclic_AMP_and_pyrophosphate._Six_distinct_non-homologous_classes_of_AC_have_been_identified._The_structure_of_...

description:
  These sequences are functionally identified as members of the adenylate cyclase family, which catalyses the conversion of ATP to 3,5-cyclic AMP and pyrophosphate. Six distinct non-homologous classes of AC have been identified. The structure of ...


id: SM01120
description: This domain is the predicted phosphatase domain of the dihydroxyacetone kinase family.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01120
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01120_This_domain_is_the_predicted_phosphatase_domain_of_the_dihydroxyacetone_kinase_family.


id: SM01122
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01122
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01122_DBC1_and_it_homologs_from_diverse_eukaryotes_are_a_catalytically_inactive_version_of_the_Nudix_hydrolase_(MutT)_domain_(PUBMED:18418069)._DBC1_is_predicted_to_bind_NAD_metabolites_and_regulate_the_activity_of_SIRT1_or_related_deacetylases_by_sensing_...

description:
  DBC1 and it homologs from diverse eukaryotes are a catalytically inactive version of the Nudix hydrolase (MutT) domain (PUBMED:18418069). DBC1 is predicted to bind NAD metabolites and regulate the activity of SIRT1 or related deacetylases by sensing ...


id: SM01124
description: Lariat debranching enzyme, C-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01124
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01124_Lariat_debranching_enzyme,_C-terminal_domain


id: SM01127
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01127
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01127_The_DDHD_domain_is_180_residues_long_and_contains_four_conserved_residues_that_may_form_a_metal_binding_site._The_domain_is_named_after_these_four_residues._This_pattern_of_conservation_of_metal_binding_residues_is_often_seen_in_phosphoesterase_...

description:
  The DDHD domain is 180 residues long and contains four conserved residues that may form a metal binding site. The domain is named after these four residues. This pattern of conservation of metal binding residues is often seen in phosphoesterase ...


id: SM01128
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01128
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01128_This_is_a_family_of_proteins_of_approximately_300_residues,_found_in_plants_and_vertebrates._They_contain_a_highly_conserved_DDRGK_motif.

description:
  This is a family of proteins of approximately 300 residues, found in plants and vertebrates. They contain a highly conserved DDRGK motif.


id: SM01129
description: Transcriptional regulator DELLA protein N terminal
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01129
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01129_Transcriptional_regulator_DELLA_protein_N_terminal


id: SM01131
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01131
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01131_This_domain_is_often_found_adjacent_to_the_DHH_domain_PF01368_and_is_called_DHHA2_for_DHH_associated_domain._This_domain_is_diagnostic_of_DHH_subfamily_2_members_(PUBMED:9478130)._The_domain_is_about_120_residues_long_and_contains_a_conserved_DXK_...

description:
  This domain is often found adjacent to the DHH domain PF01368 and is called DHHA2 for DHH associated domain. This domain is diagnostic of DHH subfamily 2 members (PUBMED:9478130). The domain is about 120 residues long and contains a conserved DXK ...


id: SM01135
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01135
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01135_DIRP_(Domain_in_Rb-related_Pathway)_is_postulated_to_be_involved_in_the_Rb-related_pathway,_which_is_encoded_by_multiple_eukaryotic_genomes_and_is_present_in_proteins_including_lin-9_of_Caenorhabditis_elegans,_aly_of_fruit_fly_and_mustard_weed._...

description:
  DIRP (Domain in Rb-related Pathway) is postulated to be involved in the Rb-related pathway, which is encoded by multiple eukaryotic genomes and is present in proteins including lin-9 of Caenorhabditis elegans, aly of fruit fly and mustard weed. ...


id: SM01142
description: This C terminal domain is found in DOB1/SK12/helY-like DEAD box helicases [PUBMED:15112237].
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01142
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01142_This_C_terminal_domain_is_found_in_DOB1/SK12/helY-like_DEAD_box_helicases_[PUBMED:15112237].


id: SM01144
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01144
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01144_This_presumed_domain_is_found_in_bacterial_and_eukaryotic_proteins._Its_function_is_unknown._The_domain_contains_multiple_conserved_motifs_including_a_DTXW_motif_that_this_domain_has_been_named_after.

description:
  This presumed domain is found in bacterial and eukaryotic proteins. Its function is unknown. The domain contains multiple conserved motifs including a DTXW motif that this domain has been named after.


id: SM01147
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01147
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01147_Members_of_this_family_are_found_in_various_chromatin_remodelling_factors_and_transposases._Their_exact_function_is,_as_yet,_unknown.

description:
  Members of this family are found in various chromatin remodelling factors and transposases. Their exact function is, as yet, unknown.


id: SM01151
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01151
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01151_This_domain,_which_is_usually_found_tandemly_repeated,_is_found_various_receptor_co-activating_proteins.

description:
  This domain, which is usually found tandemly repeated, is found various receptor co-activating proteins.


id: SM01154
description: This family contains many hypothetical proteins.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01154
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01154_This_family_contains_many_hypothetical_proteins.


id: SM01155
description: Mitochondrial domain of unknown function (DUF1713)
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01155
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01155_Mitochondrial_domain_of_unknown_function_(DUF1713)


id: SM01156
description: Eukaryotic domain of unknown function (DUF1716)
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01156
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01156_Eukaryotic_domain_of_unknown_function_(DUF1716)


id: SM01158
description: This is a eukaryotic domain of unknown function.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01158
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01158_This_is_a_eukaryotic_domain_of_unknown_function.


id: SM01159
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01159
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01159_This_domain_is_found_on_the_epsilon_catalytic_subunit_of_DNA_polymerase._It_is_found_C_terminal_to_POLBc_(SM00486).

description:
  This domain is found on the epsilon catalytic subunit of DNA polymerase. It is found C terminal to POLBc (SM00486).


id: SM01160
description: Eukaryotic integral membrane protein (DUF1751)
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01160
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01160_Eukaryotic_integral_membrane_protein_(DUF1751)


id: SM01161
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01161
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01161_Eukaryotic_domain_of_unknown_function._This_domain_is_found_to_the_N-terminus_of_the_nucleic_acid_binding_domain.

description:
  Eukaryotic domain of unknown function. This domain is found to the N-terminus of the nucleic acid binding domain.


id: SM01162
description: This domain is always found adjacent to SMR (SM00463).
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01162
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01162_This_domain_is_always_found_adjacent_to_SMR_(SM00463).


id: SM01163
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01163
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01163_This_region_is_found_in_argonaute_[PUBMED:16216572]_proteins_and_often_co-occurs_with_BAG_(SM00264)_and_Piwi_(SM00950).

description:
  This region is found in argonaute [PUBMED:16216572] proteins and often co-occurs with BAG (SM00264) and Piwi (SM00950).


id: SM01164
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01164
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01164_This_domain_has_no_known_function._It_is_found_in_the_C-terminal_segment_of_various_vasopressin_receptors.

description:
  This domain has no known function. It is found in the C-terminal segment of various vasopressin receptors.


id: SM01165
description: This domain, found in Synaptojanin, has no known function.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01165
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01165_This_domain,_found_in_Synaptojanin,_has_no_known_function.


id: SM01166
description: This set of domains is found in various eukaryotic proteins. Function is unknown.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01166
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01166_This_set_of_domains_is_found_in_various_eukaryotic_proteins._Function_is_unknown.


id: SM01167
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01167
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01167_This_domain_is_predominantly_found_in_the_structural_protein_coronin,_and_is_duplicated_in_some_sequences._It_has_no_known_function_[PUBMED:16172398].

description:
  This domain is predominantly found in the structural protein coronin, and is duplicated in some sequences. It has no known function [PUBMED:16172398].


id: SM01168
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01168
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01168_The_structure_of_this_domain_displays_an_alpha-beta-beta-alpha_four_layer_topology,_with_an_HxHxxxxxxxxxH_motif_that_coordinates_a_zinc_ion,_and_an_acetate_anion_at_a_site_that_likely_supports_the_enzymatic_activity_of_an_ester_hydrolase_...

description:
  The structure of this domain displays an alpha-beta-beta-alpha four layer topology, with an HxHxxxxxxxxxH motif that coordinates a zinc ion, and an acetate anion at a site that likely supports the enzymatic activity of an ester hydrolase ...


id: SM01169
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01169
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01169_Members_of_this_family_adopt_a_structure_consisting_of_several_large_open_beta-sheets._Their_exact_function_has_not,_as_yet,_been_determined_[PUBMED:12135361].

description:
  Members of this family adopt a structure consisting of several large open beta-sheets. Their exact function has not, as yet, been determined [PUBMED:12135361].


id: SM01173
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01173
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01173_This_family_is_found_at_the_very_C-terminus_of_proteins_that_carry_a_G-patch_domain_SM00443._The_domain_is_short_and_cysteine-rich_.

description:
  This family is found at the very C-terminus of proteins that carry a G-patch domain SM00443. The domain is short and cysteine-rich .


id: SM01174
description: The proteins in this family are uncharacterized but often named FAM188B.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01174
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01174_The_proteins_in_this_family_are_uncharacterized_but_often_named_FAM188B.


id: SM01175
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01175
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01175_This_is_a_family_of_cysteine-rich_proteins._Many_members_also_carry_a_pleckstrin-homology_domain,SM00233.

description:
  This is a family of cysteine-rich proteins. Many members also carry a pleckstrin-homology domain,SM00233.


id: SM01176
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01176
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01176_This_domain_is_found_at_the_C-terminus_of_chromodomain-helicase-DNA-binding_proteins._The_exact_function_of_the_domain_is_undetermined.

description:
  This domain is found at the C-terminus of chromodomain-helicase-DNA-binding proteins. The exact function of the domain is undetermined.


id: SM01177
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01177
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01177_This_short_domain_is_found_in_fungi,_plants_and_animals,_and_the_proteins_appear_to_be_necessary_for_chromosome_segregation_during_meiosis.

description:
  This short domain is found in fungi, plants and animals, and the proteins appear to be necessary for chromosome segregation during meiosis.


id: SM01178
description: This short domain is found at the C-terminus of many helicase proteins.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01178
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01178_This_short_domain_is_found_at_the_C-terminus_of_many_helicase_proteins.


id: SM01180
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01180
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01180_DWNN_is_a_ubiquitin_like_domain_found_at_the_N-terminus_of_the_RBBP6_family_of_splicing-associated_proteins_PUBMED:16396680._The_DWNN_domain_is_independently_expressed_in_higher_vertebrates_so_it_may_function_as_a_novel_ubiquitin-like_modifier_of_...

description:
  DWNN is a ubiquitin like domain found at the N-terminus of the RBBP6 family of splicing-associated proteins PUBMED:16396680. The DWNN domain is independently expressed in higher vertebrates so it may function as a novel ubiquitin-like modifier of ...


id: SM01181
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01181
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01181_E1_and_E2_enzymes_play_a_central_role_in_ubiquitin_and_ubiquitin-like_protein_transfer_cascades._This_is_an_E2_binding_domain_that_is_found_on_NEDD8_activating_E1_enzyme._The_domain_resembles_ubiquitin,_and_recruits_the_catalytic_core_of_the_E2_...

description:
  E1 and E2 enzymes play a central role in ubiquitin and ubiquitin-like protein transfer cascades. This is an E2 binding domain that is found on NEDD8 activating E1 enzyme. The domain resembles ubiquitin, and recruits the catalytic core of the E2 ...


id: SM01182
description: Eukaryotic elongation factor 1 beta central acidic region
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01182
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01182_Eukaryotic_elongation_factor_1_beta_central_acidic_region


id: SM01183
description: Elongation factor 1 gamma, conserved domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01183
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01183_Elongation_factor_1_gamma,_conserved_domain


id: SM01188
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01188
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01188_This_domain_is_required_for_the_nuclear_localisation_of_these_proteins_PUBMED:11352458._All_of_these_proteins_are_members_of_the_Tale/Knox_homeodomain_family,_a_subfamily_within_homeobox_SM00389.

description:
  This domain is required for the nuclear localisation of these proteins PUBMED:11352458. All of these proteins are members of the Tale/Knox homeodomain family, a subfamily within homeobox SM00389.


id: SM01189
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01189
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01189_The_ELM2_(Egl-27_and_MTA1_homology_2)_domain_is_a_small_domain_of_unknown_function._It_is_found_in_the_MTA1_protein_that_is_part_of_the_NuRD_complex_PUBMED:10226007._The_domain_is_usually_found_to_the_N_terminus_of_a_myb-like_DNA_binding_domain_SANT_...

description:
  The ELM2 (Egl-27 and MTA1 homology 2) domain is a small domain of unknown function. It is found in the MTA1 protein that is part of the NuRD complex PUBMED:10226007. The domain is usually found to the N terminus of a myb-like DNA binding domain SANT ...


id: SM01191
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01191
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01191_This_presumed_domain_is_named_after_Emsy_N_Terminus_(ENT)._Emsy_is_a_protein_that_is_amplified_in_breast_cancer_and_interacts_with_BRCA2._The_N_terminus_of_this_protein_is_found_to_be_similar_to_other_vertebrate_and_plant_proteins_of_unknown_...

description:
  This presumed domain is named after Emsy N Terminus (ENT). Emsy is a protein that is amplified in breast cancer and interacts with BRCA2. The N terminus of this protein is found to be similar to other vertebrate and plant proteins of unknown ...


id: SM01194
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01194
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01194_The_release_factor_eRF1_terminates_protein_biosynthesis_by_recognising_stop_codons_at_the_A_site_of_the_ribosome_and_stimulating_peptidyl-tRNA_bond_hydrolysis_at_the_peptidyl_transferase_centre._The_crystal_structure_of_human_eRF1_is_known_...

description:
  The release factor eRF1 terminates protein biosynthesis by recognising stop codons at the A site of the ribosome and stimulating peptidyl-tRNA bond hydrolysis at the peptidyl transferase centre. The crystal structure of human eRF1 is known ...


id: SM01199
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01199
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01199_The_FDF_domain,_so_called_because_of_the_conserved_FDF_at_its_N_termini,_is_an_entirely_alpha-helical_domain_with_multiple_exposed_hydrophilic_loops._It_is_found_at_the_C_terminus_of_Scd6p-like_SM_domains._It_is_also_found_with_other_divergent_Sm_...

description:
  The FDF domain, so called because of the conserved FDF at its N termini, is an entirely alpha-helical domain with multiple exposed hydrophilic loops. It is found at the C terminus of Scd6p-like SM domains. It is also found with other divergent Sm ...


id: SM01200
description: This is central domain A in proteins of the Ferlin family. PMID: 15112237
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01200
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01200_This_is_central_domain_A_in_proteins_of_the_Ferlin_family._PMID:_15112237


id: SM01201
description: This is central domain B in proteins of the Ferlin family. PMID: 15112237
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01201
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01201_This_is_central_domain_B_in_proteins_of_the_Ferlin_family._PMID:_15112237


id: SM01202
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01202
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01202_This_domain_is_present_in_proteins_of_the_Ferlin_family._It_is_often_located_between_two_C2_domains_PMID:15112237_.

description:
  This domain is present in proteins of the Ferlin family. It is often located between two C2 domains PMID:15112237 .


id: SM01203
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01203
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01203_This_domain_is_found_in_eukaryotes._This_domain_is_typically_between_135_and_149_amino_acids_in_length_and_is_found_associated_with_the_CH_domain.

description:
  This domain is found in eukaryotes. This domain is typically between 135 and 149 amino acids in length and is found associated with the CH domain.


id: SM01204
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01204
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01204_The_FIST_C_domain_is_a_novel_sensory_domain,_which_is_present_in_signal_transduction_proteins_from_Bacteria,_Archaea_and_Eukarya._Chromosomal_proximity_of_FIST-encoding_genes_to_those_coding_for_proteins_involved_in_amino_acid_metabolism_and_...

description:
  The FIST C domain is a novel sensory domain, which is present in signal transduction proteins from Bacteria, Archaea and Eukarya. Chromosomal proximity of FIST-encoding genes to those coding for proteins involved in amino acid metabolism and ...


id: SM01209
description: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01209
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01209_Phosphoribosylglycinamide_synthetase,_ATP-grasp_(A)_domain


id: SM01210
description: Phosphoribosylglycinamide synthetase, C domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01210
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01210_Phosphoribosylglycinamide_synthetase,_C_domain


id: SM01211
description: CobB/CobQ-like glutamine amidotransferase domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01211
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01211_CobB/CobQ-like_glutamine_amidotransferase_domain


id: SM01214
description: RNA pol II promoter Fmp27 protein domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01214
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01214_RNA_pol_II_promoter_Fmp27_protein_domain


id: SM01218
description: C-terminal duplication domain of Friend of PRMT1
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01218
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01218_C-terminal_duplication_domain_of_Friend_of_PRMT1


id: SM01220
description: Fragile site-associated protein C-terminus
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01220
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01220_Fragile_site-associated_protein_C-terminus


id: SM01222
description: Formiminotransferase domain, N-terminal subdomain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01222
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01222_Formiminotransferase_domain,_N-terminal_subdomain


id: SM01225
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01225
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01225_This_domain_is_found_in_disease_proteins_PKHD1_and_KIAA1199_and_is_named_G8_after_its_8_conserved_glycines._It_is_predicted_to_contain_10_beta_strands_and_an_alpha_helix.

description:
  This domain is found in disease proteins PKHD1 and KIAA1199 and is named G8 after its 8 conserved glycines. It is predicted to contain 10 beta strands and an alpha helix.


id: SM01229
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01229
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01229_This_is_the_proline-rich_region_of_metabotropic_glutamate_receptor_proteins_that_binds_Homer-related_synaptic_proteins._The_Homer_proteins_form_a_physical_tether_linking_mGluRs_with_the_inositol_trisphosphate_receptors_(IP3R)_that_appears_to_be_due_...

description:
  This is the proline-rich region of metabotropic glutamate receptor proteins that binds Homer-related synaptic proteins. The Homer proteins form a physical tether linking mGluRs with the inositol trisphosphate receptors (IP3R) that appears to be due ...


id: SM01232
description: Formamidopyrimidine-DNA glycosylase H2TH domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01232
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01232_Formamidopyrimidine-DNA_glycosylase_H2TH_domain


id: SM01237
description: Islet cell autoantigen ICA69, C-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01237
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01237_Islet_cell_autoantigen_ICA69,_C-terminal_domain


id: SM01240
description: IMP dehydrogenase / GMP reductase domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01240
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01240_IMP_dehydrogenase_/_GMP_reductase_domain


id: SM01241
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01241
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01241_Integrins_are_a_group_of_transmembrane_proteins_which_function_as_extracellular_matrix_receptors_and_in_cell_adhesion._Integrins_are_ubiquitously_expressed_and_are_heterodimeric,_each_composed_of_an_alpha_and_beta_subunit._Several_variations_of_the_...

description:
  Integrins are a group of transmembrane proteins which function as extracellular matrix receptors and in cell adhesion. Integrins are ubiquitously expressed and are heterodimeric, each composed of an alpha and beta subunit. Several variations of the ...


id: SM01242
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01242
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01242_This_is_the_beta_tail_domain_of_the_Integrin_protein._Integrins_are_receptors_which_are_involved_in_cell-cell_and_cell-extracellular_matrix_interactions.

description:
  This is the beta tail domain of the Integrin protein. Integrins are receptors which are involved in cell-cell and cell-extracellular matrix interactions.


id: SM01253
description: Domain of Kin17 curved DNA-binding protein
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01253
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01253_Domain_of_Kin17_curved_DNA-binding_protein


id: SM01254
description: Predicted coiled-coil domain-containing protein
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01254
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01254_Predicted_coiled-coil_domain-containing_protein


id: SM01257
description: Ki-ras-induced actin-interacting protein-IP3R-interacting domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01257
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01257_Ki-ras-induced_actin-interacting_protein-IP3R-interacting_domain


id: SM01261
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01261
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01261_Short_protein_of_49_amino_acid_isolated_from_bovine_spleen_cells_PUBMED:7306506._Thymopoietins_(TMPOs)_are_a_group_of_ubiquitously_expressed_nuclear_proteins._They_are_suggested_to_play_an_important_role_in_nuclear_envelope_organisation_and_cell_...

description:
  Short protein of 49 amino acid isolated from bovine spleen cells PUBMED:7306506. Thymopoietins (TMPOs) are a group of ubiquitously expressed nuclear proteins. They are suggested to play an important role in nuclear envelope organisation and cell ...


id: SM01265
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01265
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01265_This_family_contains_Mab-21_and_Mab-21_like_proteins._In_C._elegans_these_proteins_are_required_for_several_aspects_of_embryonic_development_PUBMED:8582275

description:
  This family contains Mab-21 and Mab-21 like proteins. In C. elegans these proteins are required for several aspects of embryonic development PUBMED:8582275


id: SM01272
description: This domain is found associated with Lsm domain PMID:16115810.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01272
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01272_This_domain_is_found_associated_with_Lsm_domain_PMID:16115810.


id: SM01277
description: Polyubiquitination (PEST) N-terminal domain of MAGUK
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01277
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01277_Polyubiquitination_(PEST)_N-terminal_domain_of_MAGUK


id: SM01279
description: Trimeric coiled-coil oligomerisation domain of matrilin
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01279
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01279_Trimeric_coiled-coil_oligomerisation_domain_of_matrilin


id: SM01281
description: Transcription mediator complex subunit Med12
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01281
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01281_Transcription_mediator_complex_subunit_Med12


id: SM01283
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01283
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01283_This_domain_is_found_both_alone_and_at_the_C-terminus_of_actin-binding_Rho-activating_protein_(ABRA)._It_binds_to_actin,_and_in_muscle_regulates_the_actin_cytoskeleton_and_cell_motility_PMID:11983702,_20940261._It_has_a_winged_helix-like_fold_...

description:
  This domain is found both alone and at the C-terminus of actin-binding Rho-activating protein (ABRA). It binds to actin, and in muscle regulates the actin cytoskeleton and cell motility PMID:11983702, 20940261. It has a winged helix-like fold ...


id: SM01291
description: COMPASS (Complex proteins associated with Set1p) component N
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01291
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01291_COMPASS_(Complex_proteins_associated_with_Set1p)_component_N


id: SM01296
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01296
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01296_This_family_features_sequences_that_are_similar_to_a_region_of_hypothetical_yeast_gene_product_N2227._This_is_thought_to_be_expressed_during_meiosis_and_may_be_involved_in_the_defence_response_to_stressful_conditions_PMID:8771715.

description:
  This family features sequences that are similar to a region of hypothetical yeast gene product N2227. This is thought to be expressed during meiosis and may be involved in the defence response to stressful conditions PMID:8771715.


id: SM01300
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01300
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01300_This_domain_was_first_identified_in_drosophila_MSL1_(male-specific_lethal_1)_PMID:12698291._In_drosophila_it_binds_to_the_histone_acetyltransferase_males-absent_on_the_first_protein_(MOF)_and_to_protein_male-specific_lethal-3_(MSL3)_PMID:15141166

description:
  This domain was first identified in drosophila MSL1 (male-specific lethal 1) PMID:12698291. In drosophila it binds to the histone acetyltransferase males-absent on the first protein (MOF) and to protein male-specific lethal-3 (MSL3) PMID:15141166


id: SM01303
description: Rapamycin-insensitive companion of mTOR RasGEF_N domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01303
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01303_Rapamycin-insensitive_companion_of_mTOR_RasGEF_N_domain


id: SM01305
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01305
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01305_This_domain_is_found_in_the_glucocorticoid-responsive_protein_regulated_endocrine-specific_protein_18_(RESP18)_and_in_the_N-terminal_extracellular_region_of_receptor-type_tyrosine-protein_phosphatases_containing_the_protein-tyrosine_phosphatase_...

description:
  This domain is found in the glucocorticoid-responsive protein regulated endocrine-specific protein 18 (RESP18) and in the N-terminal extracellular region of receptor-type tyrosine-protein phosphatases containing the protein-tyrosine phosphatase ...


id: SM01307
description: Rapamycin-insensitive companion of mTOR, middle domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01307
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01307_Rapamycin-insensitive_companion_of_mTOR,_middle_domain


id: SM01308
description: Rapamycin-insensitive companion of mTOR, N-term
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01308
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01308_Rapamycin-insensitive_companion_of_mTOR,_N-term


id: SM01309
description: Rapamycin-insensitive companion of mTOR, phosphorylation-site
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01309
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01309_Rapamycin-insensitive_companion_of_mTOR,_phosphorylation-site


id: SM01310
description: Rapamycin-insensitive companion of mTOR, domain 5
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01310
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01310_Rapamycin-insensitive_companion_of_mTOR,_domain_5


id: SM01313
description: Exocyst complex component SEC3 N-terminal PIP2 binding PH
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01313
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01313_Exocyst_complex_component_SEC3_N-terminal_PIP2_binding_PH


id: SM01314
description: Snf2-ATP coupling, chromatin remodelling complex
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01314
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01314_Snf2-ATP_coupling,_chromatin_remodelling_complex


id: SM01319
description: Tankyrase binding protein C terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01319
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01319_Tankyrase_binding_protein_C_terminal_domain


id: SM01326
description: C2 domain of PTEN tumour-suppressor protein
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01326
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01326_C2_domain_of_PTEN_tumour-suppressor_protein


id: SM01329
description: Isocitrate/isopropylmalate dehydrogenase
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01329
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01329_Isocitrate/isopropylmalate_dehydrogenase


id: SM01330
description: Frizzled/Smoothened family membrane region
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01330
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01330_Frizzled/Smoothened_family_membrane_region


id: SM01332
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01332
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01332_Cyclins_are_a_family_of_proteins_that_control_the_progression_of_cells_through_the_cell_cycle_by_activating_cyclin-dependent_kinase_(Cdk)_enzymes.

description:
  Cyclins are a family of proteins that control the progression of cells through the cell cycle by activating cyclin-dependent kinase (Cdk) enzymes.


id: SM01333
description: Oxygenase domain of the 2OGFeDO superfamily
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01333
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01333_Oxygenase_domain_of_the_2OGFeDO_superfamily


id: SM01335
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01335
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01335_This_domain_is_found_in_poly(ADP-ribose)-synthetases_(PMID:15112237)._The_function_of_this_domain_is_unknown.

description:
  This domain is found in poly(ADP-ribose)-synthetases (PMID:15112237). The function of this domain is unknown.


id: SM01336
description: Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01336
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01336_Poly(ADP-ribose)_polymerase_and_DNA-Ligase_Zn-finger_region


id: SM01337
description: Anaphase-promoting complex, subunit 10 (APC10)
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01337
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01337_Anaphase-promoting_complex,_subunit_10_(APC10)


id: SM01338
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01338
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01338_NOTCH_signalling_plays_a_fundamental_role_during_a_great_number_of_developmental_processes_in_multicellular_animals_(PMID:10221902,_11112321)._NOD_and_NODP_represent_a_region_present_in_many_NOTCH_proteins_and_NOTCH_homologs_in_multiple_species_such_...

description:
  NOTCH signalling plays a fundamental role during a great number of developmental processes in multicellular animals (PMID:10221902, 11112321). NOD and NODP represent a region present in many NOTCH proteins and NOTCH homologs in multiple species such ...


id: SM01339
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01339
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01339_NOTCH_signalling_plays_a_fundamental_role_during_a_great_number_of_developmental_processes_in_multicellular_animals_(PMID:10221902,_11112321)._NOD_and_NODP_represent_a_region_present_in_many_NOTCH_proteins_and_NOTCH_homologs_in_multiple_species_such_...

description:
  NOTCH signalling plays a fundamental role during a great number of developmental processes in multicellular animals (PMID:10221902, 11112321). NOD and NODP represent a region present in many NOTCH proteins and NOTCH homologs in multiple species such ...


id: SM01340
description: DNA mismatch repair protein, C-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01340
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01340_DNA_mismatch_repair_protein,_C-terminal_domain


id: SM01341
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01341
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01341_Members_of_this_family_adopt_a_secondary_structure_consisting_of_a_pair_of_long,_antiparallel_alpha-helices_(the_stem)_that_support_a_three-helix_bundle_(3HB)_at_their_end._The_3HB_contains_a_helix-turn-helix_motif_and_is_similar_to_the_DNA_binding_...

description:
  Members of this family adopt a secondary structure consisting of a pair of long, antiparallel alpha-helices (the stem) that support a three-helix bundle (3HB) at their end. The 3HB contains a helix-turn-helix motif and is similar to the DNA binding ...


id: SM01342
description: Telomere-length maintenance and DNA damage repair
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01342
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01342_Telomere-length_maintenance_and_DNA_damage_repair


id: SM01343
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01343
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01343_The_FATC_domain_is_named_after_FRAP,_ATM,_TRRAP_C-terminal_(PMID:10782091)._The_solution_structure_of_the_FATC_domain_suggests_it_plays_a_role_in_redox-dependent_structural_and_cellular_stability_(PMID:15772072).

description:
  The FATC domain is named after FRAP, ATM, TRRAP C-terminal (PMID:10782091). The solution structure of the FATC domain suggests it plays a role in redox-dependent structural and cellular stability (PMID:15772072).


id: SM01344
description: This is domain B in the catalytic subunit of DNA-dependent protein kinases.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01344
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01344_This_is_domain_B_in_the_catalytic_subunit_of_DNA-dependent_protein_kinases.


id: SM01349
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01349
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01349_XMAP215/Dis1_proteins,_such_as_Alp14_and_XMAP215,_increase_microtubules_dynamic_polymerization_rates_by_recruiting_soluble_αβ-tubulin_via_their_conserved_TOG_domains_to_polymerizing_microtubule_plus_ends.

description:
  XMAP215/Dis1 proteins, such as Alp14 and XMAP215, increase microtubules dynamic polymerization rates by recruiting soluble αβ-tubulin via their conserved TOG domains to polymerizing microtubule plus ends.


id: SM01350
description: 6-phosphogluconate dehydrogenase, C-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01350
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01350_6-phosphogluconate_dehydrogenase,_C-terminal_domain


id: SM01352
description: Adenomatosis polyposis coli down-regulated 1
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01352
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01352_Adenomatosis_polyposis_coli_down-regulated_1


id: SM01353
description: Apoptosis-inducing factor, mitochondrion-associated, C-term
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01353
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01353_Apoptosis-inducing_factor,_mitochondrion-associated,_C-term


id: SM01355
description: Clathrin-adaptor complex-3 beta-1 subunit C-terminal
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01355
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01355_Clathrin-adaptor_complex-3_beta-1_subunit_C-terminal


id: SM01356
description: Adaptin AP4 complex epsilon appendage platform
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01356
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01356_Adaptin_AP4_complex_epsilon_appendage_platform


id: SM01366
description: Sequence-specific DNA binding domain in TCFs.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01366
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01366_Sequence-specific_DNA_binding_domain_in_TCFs.


id: SM01368
description: Retinoblastoma-associated protein A domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01368
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01368_Retinoblastoma-associated_protein_A_domain


id: SM01371
description: Transcription factor IIA, alpha/beta subunit
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01371
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01371_Transcription_factor_IIA,_alpha/beta_subunit


id: SM01372
description: E2F/DP family winged-helix DNA-binding domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01372
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01372_E2F/DP_family_winged-helix_DNA-binding_domain


id: SM01376
description: Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01376
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01376_Eukaryotic_elongation_factor_5A_hypusine,_DNA-binding_OB_fold


id: SM01379
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01379
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01379_This_family_consists_of_several_GAGE_and_XAGE_proteins_which_are_found_exclusively_in_humans._The_function_of_this_family_is_unknown_although_they_have_been_implicated_in_human_cancers_(PMID:11992404)

description:
  This family consists of several GAGE and XAGE proteins which are found exclusively in humans. The function of this family is unknown although they have been implicated in human cancers (PMID:11992404)


id: SM01382
description: Ribosomal Proteins L2, C-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01382
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01382_Ribosomal_Proteins_L2,_C-terminal_domain


id: SM01383
description: Ribosomal Proteins L2, RNA binding domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01383
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01383_Ribosomal_Proteins_L2,_RNA_binding_domain


id: SM01392
description: Melanoma associated antigen family N terminal
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01392
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01392_Melanoma_associated_antigen_family_N_terminal


id: SM01400
description: N-terminal domain of ribose phosphate pyrophosphokinase
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01400
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01400_N-terminal_domain_of_ribose_phosphate_pyrophosphokinase


id: SM01404
description: Cation-independent mannose-6-phosphate receptor repeat
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01404
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01404_Cation-independent_mannose-6-phosphate_receptor_repeat


id: SM01406
description: Family of proteins with a conserved region found in PAPA-1, a PAP-1 binding protein.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01406
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01406_Family_of_proteins_with_a_conserved_region_found_in_PAPA-1,_a_PAP-1_binding_protein.


id: SM01408
description: Inhibitor of growth proteins N-terminal histone-binding
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01408
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01408_Inhibitor_of_growth_proteins_N-terminal_histone-binding


id: SM01419
description: Alpha-macro-globulin thiol-ester bond-forming region
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01419
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01419_Alpha-macro-globulin_thiol-ester_bond-forming_region


id: SM01422
description: Smad anchor for receptor activation (SARA)
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01422
name:
  Protein Domains (SMART).STRING_v12.0_68415_STRINGid_SM01422_Smad_anchor_for_receptor_activation_(SARA)


