# geneInfo

ensembl_gene_id: SBI_00030
symbol: SBI_00030
gene_biotype: protein_coding
description:
  Monooxygenase; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.


ensembl_gene_id: SBI_00041
symbol: SBI_00041
gene_biotype: protein_coding
description:
  COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain.


ensembl_gene_id: SBI_00042
symbol: gap1
gene_biotype: protein_coding
description:
  COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.


ensembl_gene_id: SBI_00045
symbol: SBI_00045
gene_biotype: protein_coding
description:
  Oxidoreductase, zinc-binding dehydrogenase family protein; COG1062 Zn-dependent alcohol dehydrogenases, class III.


ensembl_gene_id: SBI_00053
symbol: SBI_00053
gene_biotype: protein_coding
description:
  Putative transcriptional regulator, XRE family protein; COG1396 Predicted transcriptional regulators.


ensembl_gene_id: SBI_00062
symbol: SBI_00062
gene_biotype: protein_coding
description:
  Short chain dehydrogenase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: SBI_00065
symbol: SBI_00065
gene_biotype: protein_coding
description:
  Putative short chain dehydrogenase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: SBI_00086
symbol: SBI_00086
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family protein; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: SBI_00087
symbol: SBI_00087
gene_biotype: protein_coding
description:
  Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: SBI_00090
symbol: clpP
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease proteolytic subunit 2; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.


ensembl_gene_id: SBI_00091
symbol: clpP-2
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.


ensembl_gene_id: SBI_00093
symbol: SBI_00093
gene_biotype: protein_coding
description:
  Short-chain dehydrogenase/reductase SDR; COG4221 Short-chain alcohol dehydrogenase of unknown specificity; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: SBI_00098
symbol: SBI_00098
gene_biotype: protein_coding
description:
  COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.


ensembl_gene_id: SBI_00101
symbol: SBI_00101
gene_biotype: protein_coding
description:
  Putative 3-oxoacyl-(acyl-carrier-protein) reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: SBI_00104
symbol: SBI_00104
gene_biotype: protein_coding
description:
  Lactam utilization protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.


ensembl_gene_id: SBI_00109
symbol: SBI_00109
gene_biotype: protein_coding
description:
  Oxidoreductase alpha subunit; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: SBI_00114
symbol: SBI_00114
gene_biotype: protein_coding
description:
  Putative oxygenase; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.


ensembl_gene_id: SBI_00129
symbol: SBI_00129
gene_biotype: protein_coding
description:
  Cupin 2 conserved barrel domain protein; COG1917 Uncharacterized conserved protein, contains double-stranded beta-helix domain.


ensembl_gene_id: SBI_00130
symbol: SBI_00130
gene_biotype: protein_coding
description:
  Putative streptomycin-6-phosphate phosphatase; COG1785 Alkaline phosphatase; Belongs to the alkaline phosphatase family.


ensembl_gene_id: SBI_00140
symbol: SBI_00140
gene_biotype: protein_coding
description:
  Amino acid adenylation domain-containing protein; COG1020 Non-ribosomal peptide synthetase modules and related proteins.


ensembl_gene_id: SBI_00141
symbol: SBI_00141
gene_biotype: protein_coding
description:
  Oleoyl-(acyl-carrier-protein) hydrolase; COG3208 Predicted thioesterase involved in non-ribosomal peptide biosynthesis.


ensembl_gene_id: SBI_00148
symbol: SBI_00148
gene_biotype: protein_coding
description:
  FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COG1252 NADH dehydrogenase, FAD-containing subunit.


ensembl_gene_id: SBI_00162
symbol: SBI_00162
gene_biotype: protein_coding
description:
  Luciferase-like protein; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: SBI_00163
symbol: SBI_00163
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: SBI_00179
symbol: SBI_00179
gene_biotype: protein_coding
description:
  COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: SBI_00181
symbol: SBI_00181
gene_biotype: protein_coding
description:
  Putative ABC transporter ATP-binding protein; COG0488 ATPase components of ABC transporters with duplicated ATPase domains.


ensembl_gene_id: SBI_00191
symbol: SBI_00191
gene_biotype: protein_coding
description:
  Phenylserine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde.


ensembl_gene_id: SBI_00210
symbol: SBI_00210
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.


ensembl_gene_id: SBI_00212
symbol: kynA
gene_biotype: protein_coding
description:
  Tryptophan 23-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.


ensembl_gene_id: SBI_00213
symbol: kynU
gene_biotype: protein_coding
description:
  Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively.


ensembl_gene_id: SBI_00215
symbol: SBI_00215
gene_biotype: protein_coding
description:
  Putative alkanal monooxygenase; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: SBI_00217
symbol: menA
gene_biotype: protein_coding
description:
  1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily.


ensembl_gene_id: SBI_00239
symbol: SBI_00239
gene_biotype: protein_coding
description:
  Putative transmembrane protein; COG1457 Purine-cytosine permease and related proteins; Belongs to the purine-cytosine permease (2.A.39) family.


ensembl_gene_id: SBI_00246
symbol: SBI_00246
gene_biotype: protein_coding
description:
  Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.


ensembl_gene_id: SBI_00254
symbol: SBI_00254
gene_biotype: protein_coding
description:
  Allantoate amidohydrolase; COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases.


ensembl_gene_id: SBI_00263
symbol: SBI_00263
gene_biotype: protein_coding
description:
  Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: SBI_00266
symbol: SBI_00266
gene_biotype: protein_coding
description:
  Drug resistance transporter, EmrB/QacA subfamily protein; COG0477 Permeases of the major facilitator superfamily.


ensembl_gene_id: SBI_00270
symbol: sig1
gene_biotype: protein_coding
description:
  COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family.


ensembl_gene_id: SBI_00273
symbol: SBI_00273
gene_biotype: protein_coding
description:
  Secreted solute-binding lipoprotein; COG1653 ABC-type sugar transport system, periplasmic component.


ensembl_gene_id: SBI_00274
symbol: SBI_00274
gene_biotype: protein_coding
description:
  Binding-protein dependent transport protein; COG1175 ABC-type sugar transport systems, permease components.


ensembl_gene_id: SBI_00275
symbol: SBI_00275
gene_biotype: protein_coding
description:
  Binding-protein dependent transport protein; COG0395 ABC-type sugar transport system, permease component.


ensembl_gene_id: SBI_00277
symbol: SBI_00277
gene_biotype: protein_coding
description:
  Hypothetical protein; COG3934 Endo-beta-mannanase; Belongs to the glycosyl hydrolase 5 (cellulase A) family.


ensembl_gene_id: SBI_00280
symbol: SBI_00280
gene_biotype: protein_coding
description:
  Class II aldolase/adducin family protein; COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases.


ensembl_gene_id: SBI_00282
symbol: SBI_00282
gene_biotype: protein_coding
description:
  Putative oxidoreductase transmembrane protein; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.


ensembl_gene_id: SBI_00283
symbol: SBI_00283
gene_biotype: protein_coding
description:
  Putative transport integral membrane protein; COG0477 Permeases of the major facilitator superfamily.


ensembl_gene_id: SBI_00291
symbol: SBI_00291
gene_biotype: protein_coding
description:
  Two-component system sensor kinase for high-affinity potassium transport system; COG2205 Osmosensitive K+ channel histidine kinase.


ensembl_gene_id: SBI_00292
symbol: SBI_00292
gene_biotype: protein_coding
description:
  Putative two-component system response regulator; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: SBI_00293
symbol: kdpC
gene_biotype: protein_coding
description:
  Potassium-transporting ATPase subunit C; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.


ensembl_gene_id: SBI_00294
symbol: kdpB
gene_biotype: protein_coding
description:
  Potassium-transporting ATPase subunit B; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.


ensembl_gene_id: SBI_00295
symbol: kdpA
gene_biotype: protein_coding
description:
  Potassium-transporting ATPase subunit A; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane.


ensembl_gene_id: SBI_00315
symbol: SBI_00315
gene_biotype: protein_coding
description:
  Putative oxidoreductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: SBI_00318
symbol: SBI_00318
gene_biotype: protein_coding
description:
  Fumarate reductase/succinate dehydrogenase flavoprotein domain protein; COG3573 Predicted oxidoreductase.


ensembl_gene_id: SBI_00320
symbol: SBI_00320
gene_biotype: protein_coding
description:
  Beta-ketoacyl synthase; COG0764 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases.


ensembl_gene_id: SBI_00324
symbol: SBI_00324
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1917 Uncharacterized conserved protein, contains double-stranded beta-helix domain.


ensembl_gene_id: SBI_00325
symbol: SBI_00325
gene_biotype: protein_coding
description:
  Hypothetical protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.


ensembl_gene_id: SBI_00326
symbol: SBI_00326
gene_biotype: protein_coding
description:
  Hydroperoxide resistance protein; COG1764 Predicted redox protein, regulator of disulfide bond formation.


ensembl_gene_id: SBI_00327
symbol: SBI_00327
gene_biotype: protein_coding
description:
  Ferredoxin; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.


ensembl_gene_id: SBI_00349
symbol: SBI_00349
gene_biotype: protein_coding
description:
  Pyridine nucleotide-disulfide oxidoreductase; COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes.


ensembl_gene_id: SBI_00350
symbol: SBI_00350
gene_biotype: protein_coding
description:
  Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.


ensembl_gene_id: SBI_00353
symbol: zwf
gene_biotype: protein_coding
description:
  Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.


ensembl_gene_id: SBI_00361
symbol: SBI_00361
gene_biotype: protein_coding
description:
  Putative ABC transporter permease protein; COG0842 ABC-type multidrug transport system, permease component.


ensembl_gene_id: SBI_00365
symbol: SBI_00365
gene_biotype: protein_coding
description:
  Putative 2Fe-2S rieske nitrite reductase small subunit; COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases.


ensembl_gene_id: SBI_00367
symbol: SBI_00367
gene_biotype: protein_coding
description:
  COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit.


ensembl_gene_id: SBI_00369
symbol: SBI_00369
gene_biotype: protein_coding
description:
  Putative dehydrogenase; COG0665 Glycine/D-amino acid oxidases (deaminating); Belongs to the GcvT family.


ensembl_gene_id: SBI_00375
symbol: bga2
gene_biotype: protein_coding
description:
  Hydrolase; COG3250 Beta-galactosidase/beta-glucuronidase; Belongs to the glycosyl hydrolase 2 family.


ensembl_gene_id: SBI_00381
symbol: sig5
gene_biotype: protein_coding
description:
  COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: SBI_00386
symbol: SBI_00386
gene_biotype: protein_coding
description:
  Hypothetical protein; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: SBI_00389
symbol: SBI_00389
gene_biotype: protein_coding
description:
  Putative N-carbamoyl-L-amino acid amidohydrolase; COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases.


ensembl_gene_id: SBI_00392
symbol: SBI_00392
gene_biotype: protein_coding
description:
  Putative transcriptional regulator, PucR family protein; COG2508 Regulator of polyketide synthase expression.


ensembl_gene_id: SBI_00397
symbol: ilvB1
gene_biotype: protein_coding
description:
  Putative acetolactate synthase, large subunit; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Belongs to the TPP enzyme family.


ensembl_gene_id: SBI_00404
symbol: SBI_00404
gene_biotype: protein_coding
description:
  COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: SBI_00406
symbol: SBI_00406
gene_biotype: protein_coding
description:
  Antibiotic ABC transporter ATP-binding protein; COG0488 ATPase components of ABC transporters with duplicated ATPase domains.


ensembl_gene_id: SBI_00410
symbol: SBI_00410
gene_biotype: protein_coding
description:
  Putative two-component system sensor kinase; COG3851 Signal transduction histidine kinase, glucose-6-phosphate specific.


ensembl_gene_id: SBI_00415
symbol: SBI_00415
gene_biotype: protein_coding
description:
  Putative integral membrane transport protein; COG0395 ABC-type sugar transport system, permease component.


ensembl_gene_id: SBI_00416
symbol: SBI_00416
gene_biotype: protein_coding
description:
  Putative sugar transport integral membrane protein; COG1175 ABC-type sugar transport systems, permease components.


ensembl_gene_id: SBI_00421
symbol: SBI_00421
gene_biotype: protein_coding
description:
  FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases.


ensembl_gene_id: SBI_00426
symbol: SBI_00426
gene_biotype: protein_coding
description:
  4-hydroxythreonine-4-phosphate dehydrogenase; COG1995 Pyridoxal phosphate biosynthesis protein; Belongs to the PdxA family.


ensembl_gene_id: SBI_00428
symbol: SBI_00428
gene_biotype: protein_coding
description:
  Aldolase; COG3836 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; Belongs to the HpcH/HpaI aldolase family.


ensembl_gene_id: SBI_00429
symbol: SBI_00429
gene_biotype: protein_coding
description:
  COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: SBI_00432
symbol: SBI_00432
gene_biotype: protein_coding
description:
  Succinate-semialdehyde dehydrogenase, NADP-dependent; COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: SBI_00434
symbol: SBI_00434
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0160 4-aminobutyrate aminotransferase and related aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: SBI_00441
symbol: SBI_00441
gene_biotype: protein_coding
description:
  Alcohol dehydrogenase zinc-binding domain protein; COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases.


ensembl_gene_id: SBI_00446
symbol: SBI_00446
gene_biotype: protein_coding
description:
  Aminotransferase; COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities.


ensembl_gene_id: SBI_00451
symbol: SBI_00451
gene_biotype: protein_coding
description:
  2-dehydro-3-deoxyphosphogluconate aldolase/4- hydroxy-2-oxoglutarate aldolase; COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase.


ensembl_gene_id: SBI_00469
symbol: SBI_00469
gene_biotype: protein_coding
description:
  Probable ATP-binding component of ABC dipeptide transporter; COG4608 ABC-type oligopeptide transport system, ATPase component; Belongs to the ABC transporter superfamily.


ensembl_gene_id: SBI_00470
symbol: SBI_00470
gene_biotype: protein_coding
description:
  Putative ABC transporter ATP-binding protein; COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component; Belongs to the ABC transporter superfamily.


ensembl_gene_id: SBI_00472
symbol: SBI_00472
gene_biotype: protein_coding
description:
  ABC transporter, membrane spanning protein; COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components.


ensembl_gene_id: SBI_00473
symbol: SBI_00473
gene_biotype: protein_coding
description:
  ABC transporter, membrane spanning protein; COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components.


ensembl_gene_id: SBI_00476
symbol: SBI_00476
gene_biotype: protein_coding
description:
  Putative ABC transporter substrate-binding protein; COG0747 ABC-type dipeptide transport system, periplasmic component.


ensembl_gene_id: SBI_00477
symbol: SBI_00477
gene_biotype: protein_coding
description:
  Cation efflux system protein; COG0053 Predicted Co/Zn/Cd cation transporters; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.


ensembl_gene_id: SBI_00482
symbol: SBI_00482
gene_biotype: protein_coding
description:
  Putative ABC transporter ATP-binding subunit; COG1132 ABC-type multidrug transport system, ATPase and permease components.


ensembl_gene_id: SBI_00510
symbol: SBI_00510
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG1132 ABC-type multidrug transport system, ATPase and permease components.


ensembl_gene_id: SBI_00511
symbol: SBI_00511
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG2274 ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain.


ensembl_gene_id: SBI_00523
symbol: SBI_00523
gene_biotype: protein_coding
description:
  COG3321 Polyketide synthase modules and related proteins; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: SBI_00536
symbol: SBI_00536
gene_biotype: protein_coding
description:
  Von Willebrand factor type A; COG4245 Uncharacterized protein encoded in toxicity protection region of plasmid R478, contains von Willebrand factor (vWF) domain.


ensembl_gene_id: SBI_00558
symbol: thyA
gene_biotype: protein_coding
description:
  Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.


ensembl_gene_id: SBI_00585
symbol: SBI_00585
gene_biotype: protein_coding
description:
  Alpha-xylosidase YicI; COG1501 Alpha-glucosidases, family 31 of glycosyl hydrolases; Belongs to the glycosyl hydrolase 31 family.


ensembl_gene_id: SBI_00587
symbol: SBI_00587
gene_biotype: protein_coding
description:
  Sugar transport integral membrane protein; COG0395 ABC-type sugar transport system, permease component.


ensembl_gene_id: SBI_00588
symbol: SBI_00588
gene_biotype: protein_coding
description:
  Sugar transport integral membrane protein; COG1175 ABC-type sugar transport systems, permease components.


ensembl_gene_id: SBI_00591
symbol: SBI_00591
gene_biotype: protein_coding
description:
  Transcriptional regulator, PucR family protein; COG2508 Regulator of polyketide synthase expression.


ensembl_gene_id: SBI_00600
symbol: SBI_00600
gene_biotype: protein_coding
description:
  ABC transporter related protein; COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase; Belongs to the ABC transporter superfamily.


ensembl_gene_id: SBI_00601
symbol: SBI_00601
gene_biotype: protein_coding
description:
  Oligopeptide/dipeptide ABC transporter, ATPase subunit; COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component; Belongs to the ABC transporter superfamily.


ensembl_gene_id: SBI_00604
symbol: SBI_00604
gene_biotype: protein_coding
description:
  Extracellular solute-binding protein family 5; COG0747 ABC-type dipeptide transport system, periplasmic component.


ensembl_gene_id: SBI_00608
symbol: icmF
gene_biotype: protein_coding
description:
  Putative methylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.


ensembl_gene_id: SBI_00613
symbol: SBI_00613
gene_biotype: protein_coding
description:
  Putative oxidoreductase; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.


ensembl_gene_id: SBI_00614
symbol: SBI_00614
gene_biotype: protein_coding
description:
  Two component transcriptional regulator, LuxR family protein; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: SBI_00626
symbol: SBI_00626
gene_biotype: protein_coding
description:
  Hypothetical protein; COG2045 Phosphosulfolactate phosphohydrolase and related enzymes; Belongs to the ComB family.


ensembl_gene_id: SBI_00644
symbol: SBI_00644
gene_biotype: protein_coding
description:
  Membrane-associated oxidoreductase; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.


ensembl_gene_id: SBI_00646
symbol: SBI_00646
gene_biotype: protein_coding
description:
  Transcriptional regulator, AraC family protein; COG2207 AraC-type DNA-binding domain-containing proteins.


ensembl_gene_id: SBI_00652
symbol: SBI_00652
gene_biotype: protein_coding
description:
  Glycosyltransferase, MGT family; COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase.


ensembl_gene_id: SBI_00657
symbol: gmd
gene_biotype: protein_coding
description:
  GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose.


ensembl_gene_id: SBI_00658
symbol: SBI_00658
gene_biotype: protein_coding
description:
  LuxR family transcriptional regulator; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: SBI_00659
symbol: SBI_00659
gene_biotype: protein_coding
description:
  C4-dicarboxylate transporter/malic acid transport protein; COG1275 Tellurite resistance protein and related permeases.


ensembl_gene_id: SBI_00671
symbol: pks3-5
gene_biotype: protein_coding
description:
  Putative mixed polyketide synthase/non-ribosomal peptide synthetase; COG3321 Polyketide synthase modules and related proteins.


ensembl_gene_id: SBI_00672
symbol: SBI_00672
gene_biotype: protein_coding
description:
  Hypothetical protein; COG3321 Polyketide synthase modules and related proteins; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: SBI_00677
symbol: SBI_00677
gene_biotype: protein_coding
description:
  Putative short chain dehydrogenase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: SBI_00679
symbol: SBI_00679
gene_biotype: protein_coding
description:
  Sugar uptake ABC transporter sugar-binding protein; COG1653 ABC-type sugar transport system, periplasmic component.


ensembl_gene_id: SBI_00686
symbol: SBI_00686
gene_biotype: protein_coding
description:
  D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: SBI_00687
symbol: SBI_00687
gene_biotype: protein_coding
description:
  Mandelate racemase/muconate lactonizing protein; COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily; Belongs to the mandelate racemase/muconate lactonizing enzyme family.


ensembl_gene_id: SBI_00688
symbol: SBI_00688
gene_biotype: protein_coding
description:
  D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein; COG1052 Lactate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: SBI_00689
symbol: SBI_00689
gene_biotype: protein_coding
description:
  Extracellular solute-binding protein; COG0747 ABC-type dipeptide transport system, periplasmic component.


ensembl_gene_id: SBI_00693
symbol: SBI_00693
gene_biotype: protein_coding
description:
  Oligopeptide/dipeptide ABC transporter, ATPase subunit; COG4608 ABC-type oligopeptide transport system, ATPase component; Belongs to the ABC transporter superfamily.


ensembl_gene_id: SBI_00698
symbol: SBI_00698
gene_biotype: protein_coding
description:
  Extracellular solute-binding protein family 1; COG1653 ABC-type sugar transport system, periplasmic component.


ensembl_gene_id: SBI_00699
symbol: SBI_00699
gene_biotype: protein_coding
description:
  Mandelate racemase/muconate lactonizing enzyme family protein; COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily; Belongs to the mandelate racemase/muconate lactonizing enzyme family.


ensembl_gene_id: SBI_00700
symbol: SBI_00700
gene_biotype: protein_coding
description:
  2-hydroxyacid family dehydrogenase; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases.


ensembl_gene_id: SBI_00701
symbol: nhaA
gene_biotype: protein_coding
description:
  Na+/H+ antiporter NhaA; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.


ensembl_gene_id: SBI_00711
symbol: SBI_00711
gene_biotype: protein_coding
description:
  Thioesterase superfamily protein; COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism.


ensembl_gene_id: SBI_00720
symbol: SBI_00720
gene_biotype: protein_coding
description:
  Putative tricarboxylic transport membrane protein; COG3181 Uncharacterized protein conserved in bacteria.


ensembl_gene_id: SBI_00721
symbol: SBI_00721
gene_biotype: protein_coding
description:
  Two component system histidine kinase; COG3290 Signal transduction histidine kinase regulating citrate/malate metabolism.


ensembl_gene_id: SBI_00722
symbol: SBI_00722
gene_biotype: protein_coding
description:
  Putative two component system response regulator; COG4565 Response regulator of citrate/malate metabolism.


ensembl_gene_id: SBI_00730
symbol: SBI_00730
gene_biotype: protein_coding
description:
  Reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: SBI_00731
symbol: milF
gene_biotype: protein_coding
description:
  C-5 ketoreductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: SBI_00737
symbol: SBI_00737
gene_biotype: protein_coding
description:
  Putative Na+/metabolite cotransporter; COG0591 Na+/proline symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: SBI_00739
symbol: SBI_00739
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases.


ensembl_gene_id: SBI_00744
symbol: SBI_00744
gene_biotype: protein_coding
description:
  5-carboxymethyl-2-hydroxymuconate delta-isomerase; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).


ensembl_gene_id: SBI_00750
symbol: SBI_00750
gene_biotype: protein_coding
description:
  Putative carbohydrate transporter; COG0477 Permeases of the major facilitator superfamily; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.


ensembl_gene_id: SBI_00751
symbol: SBI_00751
gene_biotype: protein_coding
description:
  Putative 3-oxoacyl-(acyl-carrier-protein) reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: SBI_00752
symbol: SBI_00752
gene_biotype: protein_coding
description:
  Mandelate racemase / muconate lactonizing enzyme, C-terminal domain protein; COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily.


ensembl_gene_id: SBI_00758
symbol: SBI_00758
gene_biotype: protein_coding
description:
  Sulfopyruvate decarboxylase beta subunit; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase].


ensembl_gene_id: SBI_00759
symbol: SBI_00759
gene_biotype: protein_coding
description:
  Sulfopyruvate decarboxylase alpha subunit; COG4032 Predicted thiamine-pyrophosphate-binding protein.


ensembl_gene_id: SBI_00762
symbol: SBI_00762
gene_biotype: protein_coding
description:
  L-carnitine dehydratase/bile acid-inducible protein F; COG1804 Predicted acyl-CoA transferases/carnitine dehydratase; Belongs to the CoA-transferase III family.


ensembl_gene_id: SBI_00769
symbol: SBI_00769
gene_biotype: protein_coding
description:
  Putative aldoketoreductase; COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases).


ensembl_gene_id: SBI_00778
symbol: SBI_00778
gene_biotype: protein_coding
description:
  Transcriptional activator FtrA; COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain.


ensembl_gene_id: SBI_00779
symbol: SBI_00779
gene_biotype: protein_coding
description:
  ABC transporter component; COG1132 ABC-type multidrug transport system, ATPase and permease components.


ensembl_gene_id: SBI_00780
symbol: SBI_00780
gene_biotype: protein_coding
description:
  ABC transporter, ATP-binding/permease protein; COG1132 ABC-type multidrug transport system, ATPase and permease components.


ensembl_gene_id: SBI_00783
symbol: SBI_00783
gene_biotype: protein_coding
description:
  Glycoside hydrolase family 28; COG5434 Endopolygalacturonase; Belongs to the glycosyl hydrolase 28 family.


ensembl_gene_id: SBI_00796
symbol: SBI_00796
gene_biotype: protein_coding
description:
  Thiamine pyrophosphate protein central region; COG3962 Acetolactate synthase; Belongs to the TPP enzyme family.


ensembl_gene_id: SBI_00799
symbol: SBI_00799
gene_biotype: protein_coding
description:
  Sugar transporter; COG0477 Permeases of the major facilitator superfamily; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.


ensembl_gene_id: SBI_00800
symbol: iolG
gene_biotype: protein_coding
description:
  Myo-inositol 2-dehydrogenase; Involved in the oxidation of myo-inositol (MI) to 2-keto-myo- inositol (2KMI or 2-inosose).


ensembl_gene_id: SBI_00811
symbol: SBI_00811
gene_biotype: protein_coding
description:
  Alpha-N-arabinofuranosidase; COG3940 Predicted beta-xylosidase; Belongs to the glycosyl hydrolase 43 family.


ensembl_gene_id: SBI_00821
symbol: SBI_00821
gene_biotype: protein_coding
description:
  Putative FAD-dependent monooxygenase; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.


ensembl_gene_id: SBI_00830
symbol: SBI_00830
gene_biotype: protein_coding
description:
  Binding-protein-dependent transport systems inner membrane component; COG0395 ABC-type sugar transport system, permease component.


ensembl_gene_id: SBI_00832
symbol: SBI_00832
gene_biotype: protein_coding
description:
  Solute-binding protein of ABC transporter system; COG1653 ABC-type sugar transport system, periplasmic component.


ensembl_gene_id: SBI_00836
symbol: SBI_00836
gene_biotype: protein_coding
description:
  Hypothetical protein; COG2185 Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding).


ensembl_gene_id: SBI_00837
symbol: SBI_00837
gene_biotype: protein_coding
description:
  Putative two-component regulator; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: SBI_00842
symbol: SBI_00842
gene_biotype: protein_coding
description:
  Putative integral membrane protein; COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family.


ensembl_gene_id: SBI_00843
symbol: SBI_00843
gene_biotype: protein_coding
description:
  Two component system transcriptional regulator PhoP; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: SBI_00845
symbol: SBI_00845
gene_biotype: protein_coding
description:
  Monooxygenase; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: SBI_00846
symbol: SBI_00846
gene_biotype: protein_coding
description:
  Hypothetical protein; COG2329 Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides.


ensembl_gene_id: SBI_00858
symbol: lysA1
gene_biotype: protein_coding
description:
  Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.


ensembl_gene_id: SBI_00861
symbol: SBI_00861
gene_biotype: protein_coding
description:
  Multidrug-transport integral membrane protein Mmr-like protein; COG2076 Membrane transporters of cations and cationic drugs.


ensembl_gene_id: SBI_00863
symbol: SBI_00863
gene_biotype: protein_coding
description:
  Streptogrisin B precursor; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain.


ensembl_gene_id: SBI_00866
symbol: nadK
gene_biotype: protein_coding
description:
  ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.


ensembl_gene_id: SBI_00871
symbol: tal1
gene_biotype: protein_coding
description:
  Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily.


ensembl_gene_id: SBI_00877
symbol: SBI_00877
gene_biotype: protein_coding
description:
  Glucarate dehydratase; COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily; Belongs to the mandelate racemase/muconate lactonizing enzyme family.


ensembl_gene_id: SBI_00881
symbol: SBI_00881
gene_biotype: protein_coding
description:
  methylated-DNA-protein-cysteine S-methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.


ensembl_gene_id: SBI_00889
symbol: SBI_00889
gene_biotype: protein_coding
description:
  Oxidoreductase; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: SBI_00897
symbol: SBI_00897
gene_biotype: protein_coding
description:
  Oxidoreductase; COG4221 Short-chain alcohol dehydrogenase of unknown specificity; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: SBI_00905
symbol: gnd2
gene_biotype: protein_coding
description:
  6-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.


ensembl_gene_id: SBI_00907
symbol: anmK
gene_biotype: protein_coding
description:
  anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family.


ensembl_gene_id: SBI_00909
symbol: SBI_00909
gene_biotype: protein_coding
description:
  Hypothetical protein; COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1.


ensembl_gene_id: SBI_00917
symbol: SBI_00917
gene_biotype: protein_coding
description:
  Magnesium or manganese-dependent protein phosphatase; COG2208 Serine phosphatase RsbU, regulator of sigma subunit.


ensembl_gene_id: SBI_00928
symbol: SBI_00928
gene_biotype: protein_coding
description:
  Carbohydrate kinase, FGGY; COG1070 Sugar (pentulose and hexulose) kinases; Belongs to the FGGY kinase family.


ensembl_gene_id: SBI_00929
symbol: sig6
gene_biotype: protein_coding
description:
  COG1191 DNA-directed RNA polymerase specialized sigma subunit; Belongs to the sigma-70 factor family.


ensembl_gene_id: SBI_00935
symbol: bga4
gene_biotype: protein_coding
description:
  Beta-mannosidase; COG3250 Beta-galactosidase/beta-glucuronidase; Belongs to the glycosyl hydrolase 2 family.


ensembl_gene_id: SBI_00942
symbol: gap2
gene_biotype: protein_coding
description:
  Glyceraldehyde-3-phosphate dehydrogenase, type I; COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.


ensembl_gene_id: SBI_00943
symbol: SBI_00943
gene_biotype: protein_coding
description:
  Putative monooxygenase, mmyo; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: SBI_00954
symbol: nrps1-2
gene_biotype: protein_coding
description:
  Non-ribosomal peptide synthase/amino acid adenylation enzyme; COG1020 Non-ribosomal peptide synthetase modules and related proteins; Belongs to the ATP-dependent AMP-binding enzyme family.


ensembl_gene_id: SBI_00960
symbol: SBI_00960
gene_biotype: protein_coding
description:
  Amino acid adenylation domain protein; COG1020 Non-ribosomal peptide synthetase modules and related proteins.


ensembl_gene_id: SBI_00961
symbol: SBI_00961
gene_biotype: protein_coding
description:
  Transcriptional regulator, DeoR family protein; COG1349 Transcriptional regulators of sugar metabolism.


ensembl_gene_id: SBI_00973
symbol: SBI_00973
gene_biotype: protein_coding
description:
  EmrB/QacA family drug resistance transporter; COG0477 Permeases of the major facilitator superfamily.


ensembl_gene_id: SBI_00977
symbol: SBI_00977
gene_biotype: protein_coding
description:
  COG2310 Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1.


ensembl_gene_id: SBI_00987
symbol: SBI_00987
gene_biotype: protein_coding
description:
  Integral membrane protein; COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component.


ensembl_gene_id: SBI_00989
symbol: SBI_00989
gene_biotype: protein_coding
description:
  alpha-L-glutamate ligase, RimK family protein; COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase).


ensembl_gene_id: SBI_00998
symbol: SBI_00998
gene_biotype: protein_coding
description:
  Hypothetical protein; COG2843 Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation).


ensembl_gene_id: SBI_01004
symbol: SBI_01004
gene_biotype: protein_coding
description:
  COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs.


ensembl_gene_id: SBI_01012
symbol: SBI_01012
gene_biotype: protein_coding
description:
  Glyoxalase/bleomycin resistance protein/dioxygenase; COG0346 Lactoylglutathione lyase and related lyases.


ensembl_gene_id: SBI_01014
symbol: SBI_01014
gene_biotype: protein_coding
description:
  Alkanesulfonate monooxygenase; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: SBI_01017
symbol: SBI_01017
gene_biotype: protein_coding
description:
  Putative solute-binding lipoprotein; COG0747 ABC-type dipeptide transport system, periplasmic component.


ensembl_gene_id: SBI_01030
symbol: SBI_01030
gene_biotype: protein_coding
description:
  COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: SBI_01045
symbol: SBI_01045
gene_biotype: protein_coding
description:
  Carbohydrate ABC transporter; COG1132 ABC-type multidrug transport system, ATPase and permease components.


ensembl_gene_id: SBI_01049
symbol: SBI_01049
gene_biotype: protein_coding
description:
  Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; COG0526 Thiol-disulfide isomerase and thioredoxins.


ensembl_gene_id: SBI_01051
symbol: SBI_01051
gene_biotype: protein_coding
description:
  Transcriptional regulator, SARP family protein; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: SBI_01059
symbol: SBI_01059
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.


ensembl_gene_id: SBI_01064
symbol: SBI_01064
gene_biotype: protein_coding
description:
  Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.


ensembl_gene_id: SBI_01066
symbol: SBI_01066
gene_biotype: protein_coding
description:
  Secreted protease; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain.


ensembl_gene_id: SBI_01068
symbol: SBI_01068
gene_biotype: protein_coding
description:
  Streptogrisin A precursor; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain.


ensembl_gene_id: SBI_01069
symbol: SBI_01069
gene_biotype: protein_coding
description:
  Putative hydantoinase/oxoprolinase; COG0145 N-methylhydantoinase A/acetone carboxylase, beta subunit.


ensembl_gene_id: SBI_01111
symbol: SBI_01111
gene_biotype: protein_coding
description:
  Putative dihydroxyacetone kinase phosphotransfer protein; COG3412 Uncharacterized protein conserved in bacteria.


ensembl_gene_id: SBI_01197
symbol: SBI_01197
gene_biotype: protein_coding
description:
  NADH:flavin oxidoreductase/NADH oxidase; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family.


ensembl_gene_id: SBI_01201
symbol: SBI_01201
gene_biotype: protein_coding
description:
  Zinc-binding dehydrogenase; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases.


ensembl_gene_id: SBI_01212
symbol: SBI_01212
gene_biotype: protein_coding
description:
  Alcohol dehydrogenase GroES domain protein; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases.


ensembl_gene_id: SBI_01214
symbol: SBI_01214
gene_biotype: protein_coding
description:
  Putative transposase for insertion sequence element; COG3464 Transposase and inactivated derivatives.


ensembl_gene_id: SBI_01253
symbol: SBI_01253
gene_biotype: protein_coding
description:
  Hydrolase; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain.


ensembl_gene_id: SBI_01259
symbol: SBI_01259
gene_biotype: protein_coding
description:
  Periplasmic binding protein; COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component.


ensembl_gene_id: SBI_01263
symbol: SBI_01263
gene_biotype: protein_coding
description:
  Putative integral membrane protein; COG0619 ABC-type cobalt transport system, permease component CbiQ and related transporters.


ensembl_gene_id: SBI_01264
symbol: SBI_01264
gene_biotype: protein_coding
description:
  Putative ABC transporter ATP-binding protein; COG1122 ABC-type cobalt transport system, ATPase component.


ensembl_gene_id: SBI_01266
symbol: metE
gene_biotype: protein_coding
description:
  5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.


ensembl_gene_id: SBI_01273
symbol: SBI_01273
gene_biotype: protein_coding
description:
  ABC transporter solute-bing protein; COG0747 ABC-type dipeptide transport system, periplasmic component.


ensembl_gene_id: SBI_01274
symbol: SBI_01274
gene_biotype: protein_coding
description:
  ABC transporter permease protein; COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components.


ensembl_gene_id: SBI_01275
symbol: SBI_01275
gene_biotype: protein_coding
description:
  ABC transporter permease protein; COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components.


ensembl_gene_id: SBI_01276
symbol: SBI_01276
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG4172 ABC-type uncharacterized transport system, duplicated ATPase component.


ensembl_gene_id: SBI_01288
symbol: SBI_01288
gene_biotype: protein_coding
description:
  Putative sugar transport integral membrane protein; COG0395 ABC-type sugar transport system, permease component.


ensembl_gene_id: SBI_01300
symbol: SBI_01300
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog.


ensembl_gene_id: SBI_01310
symbol: SBI_01310
gene_biotype: protein_coding
description:
  Putative transmembrane transport protein; COG0395 ABC-type sugar transport system, permease component.


ensembl_gene_id: SBI_01320
symbol: SBI_01320
gene_biotype: protein_coding
description:
  2-keto-3-deoxy-6-phospho-gluconate aldolase-like protein; COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase.


ensembl_gene_id: SBI_01326
symbol: SBI_01326
gene_biotype: protein_coding
description:
  Galactonate dehydratase; COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily.


ensembl_gene_id: SBI_01327
symbol: SBI_01327
gene_biotype: protein_coding
description:
  Glycosyl hydrolase; COG1501 Alpha-glucosidases, family 31 of glycosyl hydrolases; Belongs to the glycosyl hydrolase 31 family.


ensembl_gene_id: SBI_01341
symbol: SBI_01341
gene_biotype: protein_coding
description:
  COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: SBI_01342
symbol: SBI_01342
gene_biotype: protein_coding
description:
  Putative carboxymuconolactone decarboxylase family protein; COG0599 Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit.


ensembl_gene_id: SBI_01361
symbol: SBI_01361
gene_biotype: protein_coding
description:
  Putative CoA-binding protein; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases.


ensembl_gene_id: SBI_01374
symbol: SBI_01374
gene_biotype: protein_coding
description:
  Polyketide synthase, Pks12; COG3321 Polyketide synthase modules and related proteins; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: SBI_01378
symbol: SBI_01378
gene_biotype: protein_coding
description:
  COG0332 3-oxoacyl-[acyl-carrier-protein] synthase III; Belongs to the thiolase-like superfamily. FabH family.


ensembl_gene_id: SBI_01409
symbol: SBI_01409
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0580 Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family).


ensembl_gene_id: SBI_01415
symbol: vapC
gene_biotype: protein_coding
description:
  Hypothetical protein; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family.


ensembl_gene_id: SBI_01431
symbol: SBI_01431
gene_biotype: protein_coding
description:
  Oligopeptide/dipeptide ABC transporter, ATP-binding protein-like protein; COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component; Belongs to the ABC transporter superfamily.


ensembl_gene_id: SBI_01435
symbol: SBI_01435
gene_biotype: protein_coding
description:
  Twin-arginine translocation pathway signal; COG0747 ABC-type dipeptide transport system, periplasmic component.


ensembl_gene_id: SBI_01437
symbol: SBI_01437
gene_biotype: protein_coding
description:
  Allophanate hydrolase; COG0154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases.


ensembl_gene_id: SBI_01449
symbol: rpsN
gene_biotype: protein_coding
description:
  30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family.


ensembl_gene_id: SBI_01453
symbol: rpsR1
gene_biotype: protein_coding
description:
  30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.


ensembl_gene_id: SBI_01493
symbol: SBI_01493
gene_biotype: protein_coding
description:
  Putative oxalyl-CoA decarboxylase; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase].


ensembl_gene_id: SBI_01513
symbol: SBI_01513
gene_biotype: protein_coding
description:
  Putative oxidoreductase; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: SBI_01523
symbol: SBI_01523
gene_biotype: protein_coding
description:
  Short chain dehydrogenase protein; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: SBI_01525
symbol: SBI_01525
gene_biotype: protein_coding
description:
  Short-chain family oxidoreductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: SBI_01527
symbol: SBI_01527
gene_biotype: protein_coding
description:
  Decarboxylase protein; COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases.


ensembl_gene_id: SBI_01531
symbol: SBI_01531
gene_biotype: protein_coding
description:
  2,4-dienoyl-CoA reductase (NADPH) protein; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family.


ensembl_gene_id: SBI_01532
symbol: SBI_01532
gene_biotype: protein_coding
description:
  2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).


ensembl_gene_id: SBI_01534
symbol: SBI_01534
gene_biotype: protein_coding
description:
  Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.


ensembl_gene_id: SBI_01535
symbol: SBI_01535
gene_biotype: protein_coding
description:
  4-hydroxy-2-ketovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family.


ensembl_gene_id: SBI_01542
symbol: SBI_01542
gene_biotype: protein_coding
description:
  Mycocerosate synthase., Erythronolide synthase; COG3321 Polyketide synthase modules and related proteins.


ensembl_gene_id: SBI_01549
symbol: dapA-2
gene_biotype: protein_coding
description:
  Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).


ensembl_gene_id: SBI_01554
symbol: glyA-3
gene_biotype: protein_coding
description:
  Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.


ensembl_gene_id: SBI_01557
symbol: SBI_01557
gene_biotype: protein_coding
description:
  Sarcosine oxidase alpha subunit family protein; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases.


ensembl_gene_id: SBI_01561
symbol: sig8
gene_biotype: protein_coding
description:
  Putative sigma factor; COG4941 Predicted RNA polymerase sigma factor containing a TPR repeat domain; Belongs to the sigma-70 factor family.


ensembl_gene_id: SBI_01569
symbol: SBI_01569
gene_biotype: protein_coding
description:
  GCN5-related N-acetyltransferase; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases.


ensembl_gene_id: SBI_01571
symbol: SBI_01571
gene_biotype: protein_coding
description:
  Aldehyde oxidase and xanthine dehydrogenase molybdopterin binding protein; COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs.


ensembl_gene_id: SBI_01572
symbol: SBI_01572
gene_biotype: protein_coding
description:
  FAD-binding molybdopterin dehydrogenase; COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs.


ensembl_gene_id: SBI_01573
symbol: SBI_01573
gene_biotype: protein_coding
description:
  2Fe-2S cluster binding protein; COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs.


ensembl_gene_id: SBI_01582
symbol: SBI_01582
gene_biotype: protein_coding
description:
  2-hydroxy-3-carboxy-6-oxo-7-methylocta-2, 4-dienoate decarboxylase; COG2159 Predicted metal-dependent hydrolase of the TIM-barrel fold.


ensembl_gene_id: SBI_01589
symbol: SBI_01589
gene_biotype: protein_coding
description:
  Putative siderophore transport system integral membrane component, FecCD family protein; COG0609 ABC-type Fe3+-siderophore transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: SBI_01590
symbol: SBI_01590
gene_biotype: protein_coding
description:
  ABC Fe+3-siderophore transporter, inner membrane subunit; COG0609 ABC-type Fe3+-siderophore transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: SBI_01591
symbol: SBI_01591
gene_biotype: protein_coding
description:
  ABC transporter related protein; COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components.


ensembl_gene_id: SBI_01592
symbol: SBI_01592
gene_biotype: protein_coding
description:
  Putative siderophore-binding lipoprotein; COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component.


ensembl_gene_id: SBI_01606
symbol: SBI_01606
gene_biotype: protein_coding
description:
  Putative secondary metabolite synthesis protein; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II.


ensembl_gene_id: SBI_01609
symbol: SBI_01609
gene_biotype: protein_coding
description:
  Putative secondary metabolite synthesis protein; COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: SBI_01635
symbol: SBI_01635
gene_biotype: protein_coding
description:
  Bifunctional deaminase-reductase-like protein; COG1985 Pyrimidine reductase, riboflavin biosynthesis.


ensembl_gene_id: SBI_01639
symbol: SBI_01639
gene_biotype: protein_coding
description:
  Putative para-aminonezoic acid synthase; COG0512 Anthranilate/para-aminobenzoate synthases component II.


ensembl_gene_id: SBI_01642
symbol: SBI_01642
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase.


ensembl_gene_id: SBI_01652
symbol: SBI_01652
gene_biotype: protein_coding
description:
  Glycosyl hydrolase family 98 putative carbohydrate binding module; Belongs to the glycosyl hydrolase 97 family.


ensembl_gene_id: SBI_01654
symbol: SBI_01654
gene_biotype: protein_coding
description:
  Soluble pyridine nucleotide transhydrogenase; COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes.


ensembl_gene_id: SBI_01663
symbol: SBI_01663
gene_biotype: protein_coding
description:
  Endoglycosylceramidase; COG1048 Aconitase A; Belongs to the glycosyl hydrolase 5 (cellulase A) family.


ensembl_gene_id: SBI_01673
symbol: echA2
gene_biotype: protein_coding
description:
  COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: SBI_01687
symbol: dctA1
gene_biotype: protein_coding
description:
  Putative sodium:dicarboxylate transport protein; COG1301 Na+/H+-dicarboxylate symporters; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: SBI_01713
symbol: SBI_01713
gene_biotype: protein_coding
description:
  Secreted protein; COG4632 Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase.


ensembl_gene_id: SBI_01718
symbol: egtA
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low- molecular thiol compound ergothioneine.


ensembl_gene_id: SBI_01719
symbol: egtB
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family.


ensembl_gene_id: SBI_01720
symbol: egtC
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine.


ensembl_gene_id: SBI_01721
symbol: egtD
gene_biotype: protein_coding
description:
  Probable methyltransferase; Catalyzes the SAM-dependent triple methylation of the alpha- amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine; Belongs to the methyltransferase superfamily. EgtD family.


ensembl_gene_id: SBI_01723
symbol: SBI_01723
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1611 Predicted Rossmann fold nucleotide-binding protein; Belongs to the LOG family.


ensembl_gene_id: SBI_01727
symbol: SBI_01727
gene_biotype: protein_coding
description:
  Putative ABC transporter protein; COG1132 ABC-type multidrug transport system, ATPase and permease components.


ensembl_gene_id: SBI_01729
symbol: SBI_01729
gene_biotype: protein_coding
description:
  Short chain dehydrogenase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: SBI_01741
symbol: SBI_01741
gene_biotype: protein_coding
description:
  Putative transcriptional regulator, PaaX family protein; COG3327 Phenylacetic acid-responsive transcriptional repressor.


ensembl_gene_id: SBI_01753
symbol: SBI_01753
gene_biotype: protein_coding
description:
  Monooxygenase, FAD-binding protein; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.


ensembl_gene_id: SBI_01763
symbol: SBI_01763
gene_biotype: protein_coding
description:
  Putative MutT family protein; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; Belongs to the Nudix hydrolase family.


ensembl_gene_id: SBI_01764
symbol: cobN
gene_biotype: protein_coding
description:
  Cobaltochelatase subunit CobN; COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatases.


ensembl_gene_id: SBI_01765
symbol: SBI_01765
gene_biotype: protein_coding
description:
  Putative cobalamin biosynthesis protein CobG; COG0155 Sulfite reductase, beta subunit (hemoprotein).


ensembl_gene_id: SBI_01767
symbol: SBI_01767
gene_biotype: protein_coding
description:
  Bifunctional protein S-adenosyl-L-methionine-precorrin-2 methyl transferase\precorrin-3 methylase; COG2243 Precorrin-2 methylase.


ensembl_gene_id: SBI_01769
symbol: cbiD
gene_biotype: protein_coding
description:
  cobalt-precorrin-6A synthase; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.


ensembl_gene_id: SBI_01773
symbol: SBI_01773
gene_biotype: protein_coding
description:
  Arginine/ornithine transport system ATPase; COG1703 Putative periplasmic protein kinase ArgK and related GTPases of G3E family.


ensembl_gene_id: SBI_01781
symbol: SBI_01781
gene_biotype: protein_coding
description:
  Putative multidrug-efflux transporter protein; COG0477 Permeases of the major facilitator superfamily.


ensembl_gene_id: SBI_01789
symbol: SBI_01789
gene_biotype: protein_coding
description:
  Putative ABC transporter ATP-binding protein; COG1129 ABC-type sugar transport system, ATPase component.


ensembl_gene_id: SBI_01790
symbol: SBI_01790
gene_biotype: protein_coding
description:
  Sugar ABC transporter, permease protein; COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components.


ensembl_gene_id: SBI_01813
symbol: SBI_01813
gene_biotype: protein_coding
description:
  Branched-chain-amino-acid transaminase; COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase.


ensembl_gene_id: SBI_01816
symbol: SBI_01816
gene_biotype: protein_coding
description:
  Ab hydrolase, alpha/beta hydrolase fold protein; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: SBI_01818
symbol: SBI_01818
gene_biotype: protein_coding
description:
  L-lactate permease; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family.


ensembl_gene_id: SBI_01834
symbol: queE
gene_biotype: protein_coding
description:
  Radical SAM family protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.


ensembl_gene_id: SBI_01838
symbol: SBI_01838
gene_biotype: protein_coding
description:
  COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases; Belongs to the UbiD family.


ensembl_gene_id: SBI_01839
symbol: SBI_01839
gene_biotype: protein_coding
description:
  NUDIX hydrolase; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; Belongs to the Nudix hydrolase family.


ensembl_gene_id: SBI_01856
symbol: SBI_01856
gene_biotype: protein_coding
description:
  Putative starvation sensing protein; Has low D-gluconate dehydratase activity (in vitro), suggesting that it has no significant role in D-gluconate degradation in vivo. Has no detectable activity with a panel of 70 other acid sugars (in vitro); Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily.


ensembl_gene_id: SBI_01863
symbol: SBI_01863
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components.


ensembl_gene_id: SBI_01865
symbol: SBI_01865
gene_biotype: protein_coding
description:
  ABC transporter related protein; COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component.


ensembl_gene_id: SBI_01871
symbol: SBI_01871
gene_biotype: protein_coding
description:
  Putative sugar binding secreted protein; COG1653 ABC-type sugar transport system, periplasmic component.


ensembl_gene_id: SBI_01898
symbol: grpE
gene_biotype: protein_coding
description:
  Putative GrpE heat shock protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several round [...]


ensembl_gene_id: SBI_01901
symbol: clpB
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.


ensembl_gene_id: SBI_01907
symbol: SBI_01907
gene_biotype: protein_coding
description:
  Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection; Belongs to the YbaB/EbfC family.


ensembl_gene_id: SBI_01940
symbol: SBI_01940
gene_biotype: protein_coding
description:
  Two-component system regulator; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: SBI_01944
symbol: SBI_01944
gene_biotype: protein_coding
description:
  COG4992 Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: SBI_01946
symbol: fabH
gene_biotype: protein_coding
description:
  3-oxoacyl-(acyl carrier protein) synthase 3; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.


ensembl_gene_id: SBI_01948
symbol: SBI_01948
gene_biotype: protein_coding
description:
  3-oxoacyl-ACP synthase II; COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: SBI_01962
symbol: SBI_01962
gene_biotype: protein_coding
description:
  Roadblock/LC7 family protein; COG2018 Uncharacterized distant relative of homeotic protein bithoraxoid.


ensembl_gene_id: SBI_01968
symbol: katG
gene_biotype: protein_coding
description:
  Catalase/peroxidase; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily.


ensembl_gene_id: SBI_01972
symbol: SBI_01972
gene_biotype: protein_coding
description:
  Binding-protein-dependent transport systems inner membrane component; COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component.


ensembl_gene_id: SBI_01977
symbol: SBI_01977
gene_biotype: protein_coding
description:
  Perosamine synthetase; COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; Belongs to the DegT/DnrJ/EryC1 family.


ensembl_gene_id: SBI_01986
symbol: SBI_01986
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate-dependent sugar phosphotransferase; COG2190 Phosphotransferase system IIA components.


ensembl_gene_id: SBI_01987
symbol: SBI_01987
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).


ensembl_gene_id: SBI_01990
symbol: SBI_01990
gene_biotype: protein_coding
description:
  Putative glycosyl hydrolase; COG1501 Alpha-glucosidases, family 31 of glycosyl hydrolases; Belongs to the glycosyl hydrolase 31 family.


ensembl_gene_id: SBI_02004
symbol: pcp
gene_biotype: protein_coding
description:
  Pyroglutamyl-peptidase I; Removes 5-oxoproline from various penultimate amino acid residues except L-proline; Belongs to the peptidase C15 family.


ensembl_gene_id: SBI_02008
symbol: pxpA
gene_biotype: protein_coding
description:
  LamB/YcsF family protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.


ensembl_gene_id: SBI_02014
symbol: SBI_02014
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases.


ensembl_gene_id: SBI_02016
symbol: SBI_02016
gene_biotype: protein_coding
description:
  Putative binding-protein-dependent transporter integral membrane subunit; COG0395 ABC-type sugar transport system, permease component.


ensembl_gene_id: SBI_02017
symbol: SBI_02017
gene_biotype: protein_coding
description:
  Putative binding-protein-dependent transporter, integral membrane component; COG1175 ABC-type sugar transport systems, permease components.


ensembl_gene_id: SBI_02030
symbol: plsC1
gene_biotype: protein_coding
description:
  Putative 1-acylglycerol-3-phosphate O-acyltransferase; COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase.


ensembl_gene_id: SBI_02032
symbol: SBI_02032
gene_biotype: protein_coding
description:
  Oxidoreductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: SBI_02050
symbol: SBI_02050
gene_biotype: protein_coding
description:
  NADPH-ferredoxin reductase; COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases.


ensembl_gene_id: SBI_02055
symbol: ung
gene_biotype: protein_coding
description:
  uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.


ensembl_gene_id: SBI_02067
symbol: SBI_02067
gene_biotype: protein_coding
description:
  Putative nucleotide-binding protein; COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases.


ensembl_gene_id: SBI_02071
symbol: SBI_02071
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase.


ensembl_gene_id: SBI_02077
symbol: SBI_02077
gene_biotype: protein_coding
description:
  Putative OmpR family two-component response regulator; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: SBI_02092
symbol: pqqE
gene_biotype: protein_coding
description:
  Pyrroloquinoline quinone biosynthesis protein PqqE; Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).


ensembl_gene_id: SBI_02094
symbol: pqqC
gene_biotype: protein_coding
description:
  Pyrroloquinoline quinone biosynthesis protein PqqC; Ring cyclization and eight-electron oxidation of 3a-(2-amino- 2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9- dicarboxylic-acid to PQQ.


ensembl_gene_id: SBI_02095
symbol: pqqB
gene_biotype: protein_coding
description:
  Pyrroloquinoline quinone biosynthesis protein PqqB; May be involved in the transport of PQQ or its precursor to the periplasm; Belongs to the PqqB family.


ensembl_gene_id: SBI_02101
symbol: SBI_02101
gene_biotype: protein_coding
description:
  Glycosyl hydrolase family 88; COG4225 Predicted unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins.


ensembl_gene_id: SBI_02136
symbol: SBI_02136
gene_biotype: protein_coding
description:
  Sugar ABC transporter, substrate-binding protein, putative; COG1653 ABC-type sugar transport system, periplasmic component.


ensembl_gene_id: SBI_02139
symbol: SBI_02139
gene_biotype: protein_coding
description:
  6-phospho-beta-glucosidase; COG1486 Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases.


ensembl_gene_id: SBI_02141
symbol: SBI_02141
gene_biotype: protein_coding
description:
  Sugar ABC transporter solute-binding protein; COG1653 ABC-type sugar transport system, periplasmic component.


ensembl_gene_id: SBI_02142
symbol: SBI_02142
gene_biotype: protein_coding
description:
  Putative ABC transporter permease protein; COG1175 ABC-type sugar transport systems, permease components.


ensembl_gene_id: SBI_02143
symbol: SBI_02143
gene_biotype: protein_coding
description:
  Integral membrane sugar transport protein; COG0395 ABC-type sugar transport system, permease component.


ensembl_gene_id: SBI_02144
symbol: SBI_02144
gene_biotype: protein_coding
description:
  Putative zinc-binding dehydrogenase; COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases.


ensembl_gene_id: SBI_02145
symbol: SBI_02145
gene_biotype: protein_coding
description:
  Putative monooxygenase; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.


ensembl_gene_id: SBI_02163
symbol: SBI_02163
gene_biotype: protein_coding
description:
  Putative 3-oxacyl-ACP reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: SBI_02168
symbol: SBI_02168
gene_biotype: protein_coding
description:
  N5,N10- methylenetetrahydromethanopterin reductase-related protein; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: SBI_02174
symbol: SBI_02174
gene_biotype: protein_coding
description:
  Oligopeptide porter; COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase.


ensembl_gene_id: SBI_02175
symbol: SBI_02175
gene_biotype: protein_coding
description:
  ABC transporter, ATP-binding protein; COG4172 ABC-type uncharacterized transport system, duplicated ATPase component.


ensembl_gene_id: SBI_02177
symbol: SBI_02177
gene_biotype: protein_coding
description:
  ABC transporter, permease protein; COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components.


ensembl_gene_id: SBI_02182
symbol: SBI_02182
gene_biotype: protein_coding
description:
  Putative ABC transporter permease protein; COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components.


ensembl_gene_id: SBI_02211
symbol: prcB-2
gene_biotype: protein_coding
description:
  Proteasome subunit beta; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1B family.


ensembl_gene_id: SBI_02226
symbol: SBI_02226
gene_biotype: protein_coding
description:
  D-alanyl-D-alaninecarboxypeptidase/ D-alanyl-D-alanine-endopeptidase; COG2027 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4).


ensembl_gene_id: SBI_02236
symbol: SBI_02236
gene_biotype: protein_coding
description:
  Putative two component system reponse regulator; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: SBI_02248
symbol: SBI_02248
gene_biotype: protein_coding
description:
  Putative amidase; COG0154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases; Belongs to the amidase family.


ensembl_gene_id: SBI_02250
symbol: SBI_02250
gene_biotype: protein_coding
description:
  Putative ABC transporter permease protein; COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component.


ensembl_gene_id: SBI_02251
symbol: ssuB
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system.


ensembl_gene_id: SBI_02252
symbol: SBI_02252
gene_biotype: protein_coding
description:
  Putative sulfonate-binding protein precursor; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components.


ensembl_gene_id: SBI_02264
symbol: SBI_02264
gene_biotype: protein_coding
description:
  Putative AfsR-like transcriptional regulator; COG3629 DNA-binding transcriptional activator of the SARP family.


ensembl_gene_id: SBI_02268
symbol: SBI_02268
gene_biotype: protein_coding
description:
  Carbohydrate binding family 6; COG5434 Endopolygalacturonase; Belongs to the glycosyl hydrolase 28 family.


ensembl_gene_id: SBI_02272
symbol: SBI_02272
gene_biotype: protein_coding
description:
  Putative solute-binding lipoprotein; COG1879 ABC-type sugar transport system, periplasmic component.


ensembl_gene_id: SBI_02273
symbol: SBI_02273
gene_biotype: protein_coding
description:
  ABC transporter permease; COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components.


ensembl_gene_id: SBI_02275
symbol: rbsA
gene_biotype: protein_coding
description:
  Putative ABC transporter ATP-binding protein; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family.


ensembl_gene_id: SBI_02296
symbol: rbpA
gene_biotype: protein_coding
description:
  Hypothetical protein; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.


ensembl_gene_id: SBI_02299
symbol: lnt
gene_biotype: protein_coding
description:
  Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily.


ensembl_gene_id: SBI_02315
symbol: SBI_02315
gene_biotype: protein_coding
description:
  Hypothetical protein; COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.


ensembl_gene_id: SBI_02317
symbol: SBI_02317
gene_biotype: protein_coding
description:
  COG0071 Molecular chaperone (small heat shock protein); Belongs to the small heat shock protein (HSP20) family.


ensembl_gene_id: SBI_02318
symbol: trxB2
gene_biotype: protein_coding
description:
  Thioredoxin reductase; COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases.


ensembl_gene_id: SBI_02325
symbol: hisG
gene_biotype: protein_coding
description:
  ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily.


ensembl_gene_id: SBI_02327
symbol: ribH
gene_biotype: protein_coding
description:
  6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.


ensembl_gene_id: SBI_02328
symbol: ribA1
gene_biotype: protein_coding
description:
  Bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.


ensembl_gene_id: SBI_02330
symbol: SBI_02330
gene_biotype: protein_coding
description:
  Putative riboflavin/cytosine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.


ensembl_gene_id: SBI_02349
symbol: SBI_02349
gene_biotype: protein_coding
description:
  RNA-binding Sun protein; COG0144 tRNA and rRNA cytosine-C5-methylases; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.


ensembl_gene_id: SBI_02351
symbol: fmt
gene_biotype: protein_coding
description:
  methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.


ensembl_gene_id: SBI_02353
symbol: priA
gene_biotype: protein_coding
description:
  Primosome assembly protein PriA; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.


ensembl_gene_id: SBI_02354
symbol: metK
gene_biotype: protein_coding
description:
  S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.


ensembl_gene_id: SBI_02355
symbol: SBI_02355
gene_biotype: protein_coding
description:
  Bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.


ensembl_gene_id: SBI_02356
symbol: rpoZ
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.


ensembl_gene_id: SBI_02358
symbol: pyrF
gene_biotype: protein_coding
description:
  COG0284 Orotidine-5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily.


ensembl_gene_id: SBI_02359
symbol: pyrD
gene_biotype: protein_coding
description:
  Dihydroorotate dehydrogenase 2; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.


ensembl_gene_id: SBI_02363
symbol: pyrC
gene_biotype: protein_coding
description:
  Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.


ensembl_gene_id: SBI_02364
symbol: pyrB
gene_biotype: protein_coding
description:
  COG0540 Aspartate carbamoyltransferase, catalytic chain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.


ensembl_gene_id: SBI_02366
symbol: SBI_02366
gene_biotype: protein_coding
description:
  BldD regulator of morphogenesis and anitbiotic production; COG1396 Predicted transcriptional regulators.


ensembl_gene_id: SBI_02367
symbol: nusB
gene_biotype: protein_coding
description:
  Transcription antitermination protein NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.


ensembl_gene_id: SBI_02368
symbol: efp
gene_biotype: protein_coding
description:
  Elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.


ensembl_gene_id: SBI_02371
symbol: aroQ
gene_biotype: protein_coding
description:
  3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.


ensembl_gene_id: SBI_02372
symbol: aroB
gene_biotype: protein_coding
description:
  Putative shikimate kinase and 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).


ensembl_gene_id: SBI_02373
symbol: aroK
gene_biotype: protein_coding
description:
  Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.


ensembl_gene_id: SBI_02374
symbol: aroC
gene_biotype: protein_coding
description:
  Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.


ensembl_gene_id: SBI_02376
symbol: mltG
gene_biotype: protein_coding
description:
  Putative aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family.


ensembl_gene_id: SBI_02377
symbol: SBI_02377
gene_biotype: protein_coding
description:
  Holliday junction resolvase-like protein; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family.


ensembl_gene_id: SBI_02378
symbol: alaS
gene_biotype: protein_coding
description:
  alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.


ensembl_gene_id: SBI_02381
symbol: rpsD
gene_biotype: protein_coding
description:
  30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.


ensembl_gene_id: SBI_02383
symbol: SBI_02383
gene_biotype: protein_coding
description:
  Recombination factor protein RarA; COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase.


ensembl_gene_id: SBI_02391
symbol: relA2
gene_biotype: protein_coding
description:
  ppGpp synthetase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.


ensembl_gene_id: SBI_02392
symbol: apt
gene_biotype: protein_coding
description:
  Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.


ensembl_gene_id: SBI_02393
symbol: secF
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.


ensembl_gene_id: SBI_02394
symbol: secD
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.


ensembl_gene_id: SBI_02396
symbol: ruvB
gene_biotype: protein_coding
description:
  Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.


ensembl_gene_id: SBI_02397
symbol: ruvA
gene_biotype: protein_coding
description:
  Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.


ensembl_gene_id: SBI_02398
symbol: ruvC
gene_biotype: protein_coding
description:
  Holliday junction resolvase; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.


ensembl_gene_id: SBI_02400
symbol: pdxT
gene_biotype: protein_coding
description:
  Glutamine amidotransferase subunit PdxT; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.


ensembl_gene_id: SBI_02401
symbol: pdxS
gene_biotype: protein_coding
description:
  Pyridoxal biosynthesis lyase PdxS; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family.


ensembl_gene_id: SBI_02405
symbol: SBI_02405
gene_biotype: protein_coding
description:
  COG0558 Phosphatidylglycerophosphate synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: SBI_02408
symbol: SBI_02408
gene_biotype: protein_coding
description:
  HIT family protein; COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases.


ensembl_gene_id: SBI_02416
symbol: SBI_02416
gene_biotype: protein_coding
description:
  Putative binding-protein-dependent transporter transmembrane subunit; COG0395 ABC-type sugar transport system, permease component.


ensembl_gene_id: SBI_02418
symbol: SBI_02418
gene_biotype: protein_coding
description:
  Putative extracellular solute-binding lipoprotein; COG1653 ABC-type sugar transport system, periplasmic component.


ensembl_gene_id: SBI_02447
symbol: SBI_02447
gene_biotype: protein_coding
description:
  uroporphyrin-III methyltransferase; COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain); Belongs to the precorrin methyltransferase family.


ensembl_gene_id: SBI_02448
symbol: cobT-2
gene_biotype: protein_coding
description:
  Putative nicotinate-nucleotide- dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).


ensembl_gene_id: SBI_02452
symbol: SBI_02452
gene_biotype: protein_coding
description:
  ABC transporter substrate-binding protein; COG1464 ABC-type metal ion transport system, periplasmic component/surface antigen; Belongs to the nlpA lipoprotein family.


ensembl_gene_id: SBI_02455
symbol: metN
gene_biotype: protein_coding
description:
  Putative ABC transporter ATP-binding protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.


ensembl_gene_id: SBI_02467
symbol: argG
gene_biotype: protein_coding
description:
  COG0137 Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.


ensembl_gene_id: SBI_02475
symbol: SBI_02475
gene_biotype: protein_coding
description:
  Thiamine biosynthesis lipoprotein precursor; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.


ensembl_gene_id: SBI_02479
symbol: ade
gene_biotype: protein_coding
description:
  COG1001 Adenine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.


ensembl_gene_id: SBI_02481
symbol: SBI_02481
gene_biotype: protein_coding
description:
  ABC transporter substrate binding protein; COG0687 Spermidine/putrescine-binding periplasmic protein.


ensembl_gene_id: SBI_02482
symbol: SBI_02482
gene_biotype: protein_coding
description:
  COG3842 ABC-type spermidine/putrescine transport systems, ATPase components; Belongs to the ABC transporter superfamily.


ensembl_gene_id: SBI_02487
symbol: argD
gene_biotype: protein_coding
description:
  COG4992 Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.


ensembl_gene_id: SBI_02488
symbol: argB
gene_biotype: protein_coding
description:
  Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.


ensembl_gene_id: SBI_02489
symbol: argJ
gene_biotype: protein_coding
description:
  Bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.


ensembl_gene_id: SBI_02490
symbol: argC
gene_biotype: protein_coding
description:
  N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.


ensembl_gene_id: SBI_02491
symbol: SBI_02491
gene_biotype: protein_coding
description:
  Isocitrate dehydrogenase, NADP-dependent; COG2838 Monomeric isocitrate dehydrogenase; Belongs to the monomeric-type IDH family.


ensembl_gene_id: SBI_02499
symbol: SBI_02499
gene_biotype: protein_coding
description:
  Hypothetical protein; COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain.


ensembl_gene_id: SBI_02501
symbol: SBI_02501
gene_biotype: protein_coding
description:
  ABC transporter iron(III)/siderophore transport system ATP-binding protein; COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components.


ensembl_gene_id: SBI_02502
symbol: SBI_02502
gene_biotype: protein_coding
description:
  ABC transporter iron(III)/siderophore permease protein; COG0609 ABC-type Fe3+-siderophore transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: SBI_02503
symbol: SBI_02503
gene_biotype: protein_coding
description:
  ABC transporter iron(III)/siderophore-binding protein; COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component.


ensembl_gene_id: SBI_02504
symbol: SBI_02504
gene_biotype: protein_coding
description:
  Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.


ensembl_gene_id: SBI_02505
symbol: SBI_02505
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0490 Putative regulatory, ligand-binding protein related to C-terminal domains of K+ channels.


ensembl_gene_id: SBI_02506
symbol: SBI_02506
gene_biotype: protein_coding
description:
  Putative transmembrane transport protein; COG0475 Kef-type K+ transport systems, membrane components.


ensembl_gene_id: SBI_02519
symbol: SBI_02519
gene_biotype: protein_coding
description:
  ADP-ribose pyrophosphatase-like protein; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes.


ensembl_gene_id: SBI_02533
symbol: SBI_02533
gene_biotype: protein_coding
description:
  Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family.


ensembl_gene_id: SBI_02534
symbol: SBI_02534
gene_biotype: protein_coding
description:
  Putative integral membrane transport protein; COG0659 Sulfate permease and related transporters (MFS superfamily).


ensembl_gene_id: SBI_02536
symbol: SBI_02536
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; Belongs to the Nudix hydrolase family.


ensembl_gene_id: SBI_02539
symbol: pheT
gene_biotype: protein_coding
description:
  phenylalanyl-tRNA synthetase subunit beta; COG0073 EMAP domain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.


ensembl_gene_id: SBI_02540
symbol: pheS
gene_biotype: protein_coding
description:
  COG0016 Phenylalanyl-tRNA synthetase alpha subunit; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.


ensembl_gene_id: SBI_02542
symbol: tsnR2
gene_biotype: protein_coding
description:
  COG0566 rRNA methylases; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.


ensembl_gene_id: SBI_02543
symbol: rplT
gene_biotype: protein_coding
description:
  50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.


ensembl_gene_id: SBI_02545
symbol: infC
gene_biotype: protein_coding
description:
  Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.


ensembl_gene_id: SBI_02547
symbol: SBI_02547
gene_biotype: protein_coding
description:
  Putative aquaporin Z; COG0580 Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family); Belongs to the MIP/aquaporin (TC 1.A.8) family.


ensembl_gene_id: SBI_02563
symbol: SBI_02563
gene_biotype: protein_coding
description:
  Chitosanase; Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan.


ensembl_gene_id: SBI_02570
symbol: SBI_02570
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase).


ensembl_gene_id: SBI_02582
symbol: dxs1
gene_biotype: protein_coding
description:
  1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.


ensembl_gene_id: SBI_02583
symbol: ispG
gene_biotype: protein_coding
description:
  4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; COG0821 Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis.


ensembl_gene_id: SBI_02587
symbol: hopB
gene_biotype: protein_coding
description:
  Polyprenyl diphosphate synthase; COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.


ensembl_gene_id: SBI_02595
symbol: SBI_02595
gene_biotype: protein_coding
description:
  Flavin reductase domain-containing FMN-binding protein; COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family.


ensembl_gene_id: SBI_02598
symbol: SBI_02598
gene_biotype: protein_coding
description:
  3-oxoacyl-(acyl-carrier-protein) reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: SBI_02599
symbol: SBI_02599
gene_biotype: protein_coding
description:
  Beta-ketoacyl synthase; COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: SBI_02604
symbol: acpS
gene_biotype: protein_coding
description:
  4'-phosphopantetheinyl transferase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.


ensembl_gene_id: SBI_02614
symbol: SBI_02614
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding component; COG1134 ABC-type polysaccharide/polyol phosphate transport system, ATPase component.


ensembl_gene_id: SBI_02615
symbol: SBI_02615
gene_biotype: protein_coding
description:
  ABC transporter membrane component; COG1682 ABC-type polysaccharide/polyol phosphate export systems, permease component.


ensembl_gene_id: SBI_02620
symbol: SBI_02620
gene_biotype: protein_coding
description:
  Integral membrane transferase; COG0558 Phosphatidylglycerophosphate synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: SBI_02623
symbol: idi
gene_biotype: protein_coding
description:
  Isopentenyl-diphosphate delta-isomerase; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).


ensembl_gene_id: SBI_02642
symbol: SBI_02642
gene_biotype: protein_coding
description:
  Putative fatty acid oxidation complex alpha-subunit; COG1024 Enoyl-CoA hydratase/carnithine racemase.


ensembl_gene_id: SBI_02644
symbol: SBI_02644
gene_biotype: protein_coding
description:
  Fatty acid-CoA racemase; COG1804 Predicted acyl-CoA transferases/carnitine dehydratase; Belongs to the CoA-transferase III family.


ensembl_gene_id: SBI_02648
symbol: nfi
gene_biotype: protein_coding
description:
  Endonuclease V; DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.


ensembl_gene_id: SBI_02650
symbol: SBI_02650
gene_biotype: protein_coding
description:
  Putative oxidoreductase; COG4447 Uncharacterized protein related to plant photosystem II stability/assembly factor.


ensembl_gene_id: SBI_02658
symbol: SBI_02658
gene_biotype: protein_coding
description:
  Putative glycine betaine aldehyde dehydrogenase; COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: SBI_02659
symbol: SBI_02659
gene_biotype: protein_coding
description:
  Peptidase S8/S53 subtilisin kexin sedolisin; COG1404 Subtilisin-like serine proteases; Belongs to the peptidase S8 family.


ensembl_gene_id: SBI_02660
symbol: SBI_02660
gene_biotype: protein_coding
description:
  Transcriptional regulator, LuxR family protein; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: SBI_02662
symbol: SBI_02662
gene_biotype: protein_coding
description:
  Alcohol dehydrogenase zinc-binding domain protein; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases.


ensembl_gene_id: SBI_02690
symbol: SBI_02690
gene_biotype: protein_coding
description:
  COG1501 Alpha-glucosidases, family 31 of glycosyl hydrolases; Belongs to the glycosyl hydrolase 31 family.


ensembl_gene_id: SBI_02712
symbol: sucD-2
gene_biotype: protein_coding
description:
  succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.


ensembl_gene_id: SBI_02713
symbol: sucC
gene_biotype: protein_coding
description:
  succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.


ensembl_gene_id: SBI_02714
symbol: ilvB2
gene_biotype: protein_coding
description:
  Putative TPP-requiring protein; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Belongs to the TPP enzyme family.


ensembl_gene_id: SBI_02715
symbol: frc
gene_biotype: protein_coding
description:
  Formyl-coenzyme A transferase; Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl- CoA to oxalate; Belongs to the CoA-transferase III family. Frc subfamily.


ensembl_gene_id: SBI_02725
symbol: fdnG
gene_biotype: protein_coding
description:
  Putative respiratory chain oxidoreductase; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: SBI_02728
symbol: fdhD
gene_biotype: protein_coding
description:
  Formate dehydrogenase accessory protein; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.


ensembl_gene_id: SBI_02749
symbol: SBI_02749
gene_biotype: protein_coding
description:
  Drug resistance transporter EmrB/QacA subfamily protein; COG0477 Permeases of the major facilitator superfamily.


ensembl_gene_id: SBI_02761
symbol: sppF
gene_biotype: protein_coding
description:
  Polyketide hydroxylase; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases, spore-pigment gene cluster.


ensembl_gene_id: SBI_02762
symbol: SBI_02762
gene_biotype: protein_coding
description:
  Putative polyketide-based spore pigment synthesis protein; COG2329 Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides.


ensembl_gene_id: SBI_02764
symbol: sppA
gene_biotype: protein_coding
description:
  3-oxoacyl-ACP synthase I; COG0304 3-oxoacyl-(acyl-carrier-protein) synthase, spore-pigment gene cluster; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: SBI_02765
symbol: sppB
gene_biotype: protein_coding
description:
  Putative polyketide beta-ketoacyl synthase 2; COG0304 3-oxoacyl-(acyl-carrier-protein) synthase, spore-pigment gene cluster; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: SBI_02769
symbol: SBI_02769
gene_biotype: protein_coding
description:
  Biotin/lipoyl attachment domain-containing protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.


ensembl_gene_id: SBI_02778
symbol: SBI_02778
gene_biotype: protein_coding
description:
  Putative dehydrogenase; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: SBI_02779
symbol: SBI_02779
gene_biotype: protein_coding
description:
  COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Belongs to the TPP enzyme family.


ensembl_gene_id: SBI_02792
symbol: SBI_02792
gene_biotype: protein_coding
description:
  Zinc-binding dehydrogenase family oxidoreductase; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases.


ensembl_gene_id: SBI_02798
symbol: SBI_02798
gene_biotype: protein_coding
description:
  Putative esterase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: SBI_02803
symbol: SBI_02803
gene_biotype: protein_coding
description:
  Two-component regulator CutR; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: SBI_02806
symbol: SBI_02806
gene_biotype: protein_coding
description:
  Two component transcriptional regulator, winged helix family protein; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: SBI_02813
symbol: SBI_02813
gene_biotype: protein_coding
description:
  COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: SBI_02817
symbol: SBI_02817
gene_biotype: protein_coding
description:
  Flavin reductase domain-containing protein; COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family.


ensembl_gene_id: SBI_02819
symbol: pyrG
gene_biotype: protein_coding
description:
  CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.


ensembl_gene_id: SBI_02829
symbol: SBI_02829
gene_biotype: protein_coding
description:
  Ketoreductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: SBI_02837
symbol: SBI_02837
gene_biotype: protein_coding
description:
  COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit; Belongs to the HpcH/HpaI aldolase family.


ensembl_gene_id: SBI_02840
symbol: psd
gene_biotype: protein_coding
description:
  Phosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).


ensembl_gene_id: SBI_02841
symbol: SBI_02841
gene_biotype: protein_coding
description:
  COG1183 Phosphatidylserine synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: SBI_02845
symbol: SBI_02845
gene_biotype: protein_coding
description:
  Putative SIR2 family transcriptional regulator; COG0846 NAD-dependent protein deacetylases, SIR2 family.


ensembl_gene_id: SBI_02854
symbol: hemC-2
gene_biotype: protein_coding
description:
  Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.


ensembl_gene_id: SBI_02859
symbol: SBI_02859
gene_biotype: protein_coding
description:
  Putative inositol monophosphatase; COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family.


ensembl_gene_id: SBI_02862
symbol: SBI_02862
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1368 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily.


ensembl_gene_id: SBI_02865
symbol: SBI_02865
gene_biotype: protein_coding
description:
  Putative fosmidmycin resistance protein; COG0477 probable membrane efflux protein: Major Facilitator Superfamily.


ensembl_gene_id: SBI_02886
symbol: SBI_02886
gene_biotype: protein_coding
description:
  Hypothetical protein; COG4992 Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: SBI_02891
symbol: SBI_02891
gene_biotype: protein_coding
description:
  Putative thiamine biosynthesis lipoprotein; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.


ensembl_gene_id: SBI_02894
symbol: SBI_02894
gene_biotype: protein_coding
description:
  Putative two component system response regulator; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: SBI_02898
symbol: SBI_02898
gene_biotype: protein_coding
description:
  Putative glutamate ABC transporter permease protein; COG0765 ABC-type amino acid transport system, permease component.


ensembl_gene_id: SBI_02899
symbol: SBI_02899
gene_biotype: protein_coding
description:
  Putative glutamate ABC transporter substrate-binding protein; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; Belongs to the bacterial solute-binding protein 3 family.


ensembl_gene_id: SBI_02900
symbol: SBI_02900
gene_biotype: protein_coding
description:
  Glutamate uptake system ATP-binding protein; COG1126 ABC-type polar amino acid transport system, ATPase component.


ensembl_gene_id: SBI_02905
symbol: SBI_02905
gene_biotype: protein_coding
description:
  3-oxoadipate enol-lactone hydrolase/4-carboxymuconolactone decarboxylase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: SBI_02908
symbol: SBI_02908
gene_biotype: protein_coding
description:
  Sugar ABC transporter ATP-binding protein; COG1129 ABC-type sugar transport system, ATPase component.


ensembl_gene_id: SBI_02909
symbol: SBI_02909
gene_biotype: protein_coding
description:
  ABC transporter sugar permease; COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components.


ensembl_gene_id: SBI_02913
symbol: SBI_02913
gene_biotype: protein_coding
description:
  ATPase domain-containing protein; COG4608 ABC-type oligopeptide transport system, ATPase component; Belongs to the ABC transporter superfamily.


ensembl_gene_id: SBI_02914
symbol: SBI_02914
gene_biotype: protein_coding
description:
  Oligopeptide/dipeptide ABC transporter ATPase subunit; COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component; Belongs to the ABC transporter superfamily.


ensembl_gene_id: SBI_02915
symbol: SBI_02915
gene_biotype: protein_coding
description:
  Putative ABC transporter permease protein; COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components.


ensembl_gene_id: SBI_02924
symbol: SBI_02924
gene_biotype: protein_coding
description:
  Putative soluble lytic transglycosylase; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; Belongs to the bacterial solute-binding protein 3 family.


ensembl_gene_id: SBI_02925
symbol: SBI_02925
gene_biotype: protein_coding
description:
  2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase.


ensembl_gene_id: SBI_02933
symbol: SBI_02933
gene_biotype: protein_coding
description:
  RNA polymerase sigma-24 subunit, ECF subfamily protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family.


ensembl_gene_id: SBI_02935
symbol: SBI_02935
gene_biotype: protein_coding
description:
  Putative Nacht domain-containing signal transduction protein; COG5635 Predicted NTPase (NACHT family).


ensembl_gene_id: SBI_02949
symbol: SBI_02949
gene_biotype: protein_coding
description:
  Hydroxydechloroatrazine ethylaminohydrolase; COG0402 Cytosine deaminase and related metal-dependent hydrolases.


ensembl_gene_id: SBI_02950
symbol: SBI_02950
gene_biotype: protein_coding
description:
  Urate oxidase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.


ensembl_gene_id: SBI_02951
symbol: SBI_02951
gene_biotype: protein_coding
description:
  COG2351 Transthyretin-like protein; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.


ensembl_gene_id: SBI_02971
symbol: SBI_02971
gene_biotype: protein_coding
description:
  Glycoside hydrolase family 6; COG5297 Cellobiohydrolase A (1,4-beta-cellobiosidase A); Belongs to the glycosyl hydrolase family 6.


ensembl_gene_id: SBI_02973
symbol: SBI_02973
gene_biotype: protein_coding
description:
  Putative oxidoreductase; COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs.


ensembl_gene_id: SBI_02975
symbol: SBI_02975
gene_biotype: protein_coding
description:
  Putative oxidoreductase; COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs.


ensembl_gene_id: SBI_02976
symbol: pucA
gene_biotype: protein_coding
description:
  Putative oxidoreductase subunit; COG4630 Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A.


ensembl_gene_id: SBI_02983
symbol: SBI_02983
gene_biotype: protein_coding
description:
  Pyruvate dehydrogenase; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Belongs to the TPP enzyme family.


ensembl_gene_id: SBI_02985
symbol: SBI_02985
gene_biotype: protein_coding
description:
  Putative oxidoreductase; COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes.


ensembl_gene_id: SBI_02986
symbol: rsgA
gene_biotype: protein_coding
description:
  Ribosome-associated GTPase; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.


ensembl_gene_id: SBI_02987
symbol: SBI_02987
gene_biotype: protein_coding
description:
  Amino acid adenylation domain protein; COG1020 Non-ribosomal peptide synthetase modules and related proteins; Belongs to the ATP-dependent AMP-binding enzyme family.


ensembl_gene_id: SBI_02997
symbol: SBI_02997
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases.


ensembl_gene_id: SBI_03010
symbol: SBI_03010
gene_biotype: protein_coding
description:
  Putative nitrite/sulphite reductase; COG0155 Sulfite reductase, beta subunit (hemoprotein); Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.


ensembl_gene_id: SBI_03012
symbol: SBI_03012
gene_biotype: protein_coding
description:
  Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.


ensembl_gene_id: SBI_03014
symbol: SBI_03014
gene_biotype: protein_coding
description:
  Sulfate adenylyltransferase subunit 2; COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes.


ensembl_gene_id: SBI_03015
symbol: SBI_03015
gene_biotype: protein_coding
description:
  Sulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.


ensembl_gene_id: SBI_03016
symbol: SBI_03016
gene_biotype: protein_coding
description:
  ABC-type sulfate transporter periplasmic binding protein; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components.


ensembl_gene_id: SBI_03017
symbol: SBI_03017
gene_biotype: protein_coding
description:
  Putative ABC-type sulfate transporter ATP-binding protein; COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component.


ensembl_gene_id: SBI_03018
symbol: SBI_03018
gene_biotype: protein_coding
description:
  Transport system integral membrane protein; COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component.


ensembl_gene_id: SBI_03024
symbol: SBI_03024
gene_biotype: protein_coding
description:
  Exonuclease RNase T and DNA polymerase III; COG5018 Inhibitor of the KinA pathway to sporulation, predicted exonuclease.


ensembl_gene_id: SBI_03035
symbol: SBI_03035
gene_biotype: protein_coding
description:
  rRNA-adenine-N6-methyltransferase; COG0030 Dimethyladenosine transferase (rRNA methylation); Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.


ensembl_gene_id: SBI_03038
symbol: SBI_03038
gene_biotype: protein_coding
description:
  ABC transporter solute-binding protein; COG1653 ABC-type sugar transport system, periplasmic component.


ensembl_gene_id: SBI_03044
symbol: SBI_03044
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG1119 ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA.


ensembl_gene_id: SBI_03049
symbol: SBI_03049
gene_biotype: protein_coding
description:
  Glycogen debranching enzyme; COG1523 Type II secretory pathway, pullulanase PulA and related glycosidases; Belongs to the glycosyl hydrolase 13 family.


ensembl_gene_id: SBI_03053
symbol: lpdA1
gene_biotype: protein_coding
description:
  COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes.


ensembl_gene_id: SBI_03064
symbol: SBI_03064
gene_biotype: protein_coding
description:
  Putative oxidoreductase; COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase; Belongs to the MsrB Met sulfoxide reductase family.


ensembl_gene_id: SBI_03071
symbol: SBI_03071
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG4152 ABC-type uncharacterized transport system, ATPase component.


ensembl_gene_id: SBI_03080
symbol: SBI_03080
gene_biotype: protein_coding
description:
  Putative secreted protease; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: SBI_03082
symbol: SBI_03082
gene_biotype: protein_coding
description:
  4-hydroxybenzoate 3-monooxygenase; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.


ensembl_gene_id: SBI_03086
symbol: hemE
gene_biotype: protein_coding
description:
  Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.


ensembl_gene_id: SBI_03099
symbol: SBI_03099
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1075 Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold.


ensembl_gene_id: SBI_03102
symbol: SBI_03102
gene_biotype: protein_coding
description:
  Iron ABC transporter; COG0609 ABC-type Fe3+-siderophore transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: SBI_03104
symbol: SBI_03104
gene_biotype: protein_coding
description:
  Putative iron-siderophore ABC transporter ATP-binding protein; COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components.


ensembl_gene_id: SBI_03105
symbol: SBI_03105
gene_biotype: protein_coding
description:
  Putative iron-siderophore ABC transporter substrate-binding protein; COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component.


ensembl_gene_id: SBI_03109
symbol: SBI_03109
gene_biotype: protein_coding
description:
  COG4214 ABC-type xylose transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: SBI_03111
symbol: SBI_03111
gene_biotype: protein_coding
description:
  ABC transporter solute-binding protein; COG4213 ABC-type xylose transport system, periplasmic component.


ensembl_gene_id: SBI_03127
symbol: SBI_03127
gene_biotype: protein_coding
description:
  Putative ABC transporter permease protein; COG0395 ABC-type sugar transport system, permease component.


ensembl_gene_id: SBI_03152
symbol: SBI_03152
gene_biotype: protein_coding
description:
  Putative ABC transporter ATP-binding protein; COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase; Belongs to the ABC transporter superfamily.


ensembl_gene_id: SBI_03153
symbol: SBI_03153
gene_biotype: protein_coding
description:
  Putative peptide ABC transporter, ATP-binding protein; COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component; Belongs to the ABC transporter superfamily.


ensembl_gene_id: SBI_03155
symbol: SBI_03155
gene_biotype: protein_coding
description:
  Oligopeptide transport integral membrane protein; COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components.


ensembl_gene_id: SBI_03166
symbol: SBI_03166
gene_biotype: protein_coding
description:
  Putative transcriptional regulator, ArsR family protein; COG0640 Predicted transcriptional regulators.


ensembl_gene_id: SBI_03167
symbol: SBI_03167
gene_biotype: protein_coding
description:
  COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2.


ensembl_gene_id: SBI_03175
symbol: SBI_03175
gene_biotype: protein_coding
description:
  Putative integral membrane transport protein; COG0477 Permeases of the major facilitator superfamily.


ensembl_gene_id: SBI_03198
symbol: SBI_03198
gene_biotype: protein_coding
description:
  Putative ABC transporter solute-binding protein; COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component.


ensembl_gene_id: SBI_03207
symbol: SBI_03207
gene_biotype: protein_coding
description:
  salicylyl-CoA 5-hydroxylase; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.


ensembl_gene_id: SBI_03211
symbol: argF
gene_biotype: protein_coding
description:
  Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.


ensembl_gene_id: SBI_03215
symbol: SBI_03215
gene_biotype: protein_coding
description:
  Crp/Fnr family transcriptional regulator; COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases.


ensembl_gene_id: SBI_03221
symbol: SBI_03221
gene_biotype: protein_coding
description:
  Putative monooxygenase; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: SBI_03239
symbol: SBI_03239
gene_biotype: protein_coding
description:
  Putative ABC transporter transmembrane subunit; Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: SBI_03240
symbol: SBI_03240
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG3842 ABC-type spermidine/putrescine transport systems, ATPase components; Belongs to the ABC transporter superfamily.


ensembl_gene_id: SBI_03241
symbol: SBI_03241
gene_biotype: protein_coding
description:
  Assimilatory nitrate reductase large subunit; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.


ensembl_gene_id: SBI_03247
symbol: SBI_03247
gene_biotype: protein_coding
description:
  COG2265 SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.


ensembl_gene_id: SBI_03258
symbol: kdpE
gene_biotype: protein_coding
description:
  Putative two-component system response regulator for high-affinity potassium transport system; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: SBI_03259
symbol: kdpD
gene_biotype: protein_coding
description:
  Putative two-component system sensor kinase for high-affinity potassium transport system; COG2205 Osmosensitive K+ channel histidine kinase.


ensembl_gene_id: SBI_03262
symbol: dut
gene_biotype: protein_coding
description:
  Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.


ensembl_gene_id: SBI_03270
symbol: suhB
gene_biotype: protein_coding
description:
  Putative myo-inositol 1-monophosphatase; COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family.


ensembl_gene_id: SBI_03271
symbol: hemH
gene_biotype: protein_coding
description:
  Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.


ensembl_gene_id: SBI_03287
symbol: SBI_03287
gene_biotype: protein_coding
description:
  Haloacetate dehalogenase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: SBI_03291
symbol: SBI_03291
gene_biotype: protein_coding
description:
  Two-component system sensor kinase; COG3290 Signal transduction histidine kinase regulating citrate/malate metabolism.


ensembl_gene_id: SBI_03296
symbol: SBI_03296
gene_biotype: protein_coding
description:
  DNA topoisomerase IV subunit B; COG0187 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit.


ensembl_gene_id: SBI_03299
symbol: sig13
gene_biotype: protein_coding
description:
  RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.


ensembl_gene_id: SBI_03309
symbol: SBI_03309
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0406 Fructose-2,6-bisphosphatase; Belongs to the phosphoglycerate mutase family.


ensembl_gene_id: SBI_03311
symbol: nrdA
gene_biotype: protein_coding
description:
  Vitamin B12-dependent ribonucleotide reductase; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.


ensembl_gene_id: SBI_03312
symbol: nrdR
gene_biotype: protein_coding
description:
  Transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes.


ensembl_gene_id: SBI_03313
symbol: lexA
gene_biotype: protein_coding
description:
  LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.


ensembl_gene_id: SBI_03318
symbol: hflX
gene_biotype: protein_coding
description:
  ATP/GTP-binding protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.


ensembl_gene_id: SBI_03320
symbol: SBI_03320
gene_biotype: protein_coding
description:
  Putative guanosine tetraphosphate (ppGpp) metabolism protein; COG0317 Guanosine polyphosphate pyrophosphohydrolases/synthetases.


ensembl_gene_id: SBI_03321
symbol: dapF
gene_biotype: protein_coding
description:
  Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.


ensembl_gene_id: SBI_03323
symbol: miaA
gene_biotype: protein_coding
description:
  tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.


ensembl_gene_id: SBI_03327
symbol: miaB
gene_biotype: protein_coding
description:
  Adenosine tRNA methylthiotransferase; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.


ensembl_gene_id: SBI_03330
symbol: SBI_03330
gene_biotype: protein_coding
description:
  Two-component system regulator; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: SBI_03331
symbol: SBI_03331
gene_biotype: protein_coding
description:
  Putative glutamate ABC transporter ATP-binding protein; COG1126 ABC-type polar amino acid transport system, ATPase component.


ensembl_gene_id: SBI_03339
symbol: recA
gene_biotype: protein_coding
description:
  Recombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.


ensembl_gene_id: SBI_03347
symbol: nei1
gene_biotype: protein_coding
description:
  Endonuclease VIII and DNA N-glycosylase with an AP lyase activity; COG0266 Formamidopyrimidine-DNA glycosylase; Belongs to the FPG family.


ensembl_gene_id: SBI_03348
symbol: SBI_03348
gene_biotype: protein_coding
description:
  3-oxoacyl-ACP reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: SBI_03351
symbol: SBI_03351
gene_biotype: protein_coding
description:
  Putative competence-damage inducible protein; COG1546 Uncharacterized protein (competence- and mitomycin-induced); Belongs to the CinA family.


ensembl_gene_id: SBI_03353
symbol: rimO
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily.


ensembl_gene_id: SBI_03355
symbol: ftsK
gene_biotype: protein_coding
description:
  COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins; Belongs to the FtsK/SpoIIIE/SftA family.


ensembl_gene_id: SBI_03359
symbol: SBI_03359
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis.


ensembl_gene_id: SBI_03360
symbol: rnj
gene_biotype: protein_coding
description:
  Metallo-beta-lactamase family hydrolase; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.


ensembl_gene_id: SBI_03362
symbol: thyX
gene_biotype: protein_coding
description:
  FAD-dependent thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.


ensembl_gene_id: SBI_03365
symbol: SBI_03365
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components.


ensembl_gene_id: SBI_03366
symbol: dapB
gene_biotype: protein_coding
description:
  Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.


ensembl_gene_id: SBI_03368
symbol: pnp
gene_biotype: protein_coding
description:
  Polynucleotide phosphorylase/polyadenylase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.


ensembl_gene_id: SBI_03369
symbol: rpsO
gene_biotype: protein_coding
description:
  30S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.


ensembl_gene_id: SBI_03371
symbol: SBI_03371
gene_biotype: protein_coding
description:
  ATP/GTP binding protein membrane protein; COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins.


ensembl_gene_id: SBI_03397
symbol: ribF
gene_biotype: protein_coding
description:
  Bifunctional riboflavin kinase/FMN adenylyltransferase; COG0196 FAD synthase; Belongs to the ribF family.


ensembl_gene_id: SBI_03398
symbol: truB
gene_biotype: protein_coding
description:
  tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.


ensembl_gene_id: SBI_03399
symbol: rbfA
gene_biotype: protein_coding
description:
  Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.


ensembl_gene_id: SBI_03401
symbol: infB
gene_biotype: protein_coding
description:
  Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.


ensembl_gene_id: SBI_03402
symbol: SBI_03402
gene_biotype: protein_coding
description:
  Hypothetical protein; COG2740 Predicted nucleic-acid-binding protein implicated in transcription termination.


ensembl_gene_id: SBI_03403
symbol: nusA
gene_biotype: protein_coding
description:
  Transcription elongation factor NusA; Participates in both transcription termination and antitermination.


ensembl_gene_id: SBI_03404
symbol: rimP
gene_biotype: protein_coding
description:
  Hypothetical protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.


ensembl_gene_id: SBI_03408
symbol: proS1
gene_biotype: protein_coding
description:
  prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...]


ensembl_gene_id: SBI_03411
symbol: ispG-2
gene_biotype: protein_coding
description:
  4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family.


ensembl_gene_id: SBI_03413
symbol: dxr
gene_biotype: protein_coding
description:
  1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family.


ensembl_gene_id: SBI_03422
symbol: SBI_03422
gene_biotype: protein_coding
description:
  Putative transporter integral membrane binding protein; COG0395 ABC-type sugar transport system, permease component.


ensembl_gene_id: SBI_03429
symbol: SBI_03429
gene_biotype: protein_coding
description:
  COG0160 4-aminobutyrate aminotransferase and related aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: SBI_03431
symbol: SBI_03431
gene_biotype: protein_coding
description:
  Putative polyamine transport protein; COG1177 ABC-type spermidine/putrescine transport system, permease component II.


ensembl_gene_id: SBI_03439
symbol: SBI_03439
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG1136 ABC-type antimicrobial peptide transport system, ATPase component.


ensembl_gene_id: SBI_03443
symbol: fbpC
gene_biotype: protein_coding
description:
  Putative ABC transporter; Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import. Responsible for energy coupling to the transport system.


ensembl_gene_id: SBI_03445
symbol: SBI_03445
gene_biotype: protein_coding
description:
  Putative solute-binding transport system protein; COG4143 ABC-type thiamine transport system, periplasmic component.


ensembl_gene_id: SBI_03446
symbol: rlmN
gene_biotype: protein_coding
description:
  Ribosomal RNA large subunit methyltransferase N; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family.


ensembl_gene_id: SBI_03448
symbol: frr
gene_biotype: protein_coding
description:
  Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.


ensembl_gene_id: SBI_03450
symbol: tsf
gene_biotype: protein_coding
description:
  Elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.


ensembl_gene_id: SBI_03454
symbol: whiG
gene_biotype: protein_coding
description:
  RNA polymerase sigma factor WhiG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.


ensembl_gene_id: SBI_03455
symbol: SBI_03455
gene_biotype: protein_coding
description:
  DNA processing Smf-family protein; COG0758 Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake.


ensembl_gene_id: SBI_03457
symbol: SBI_03457
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0792 Predicted endonuclease distantly related to archaeal Holliday junction resolvase; Belongs to the UPF0102 family.


ensembl_gene_id: SBI_03464
symbol: rplS
gene_biotype: protein_coding
description:
  50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.


ensembl_gene_id: SBI_03465
symbol: rimM
gene_biotype: protein_coding
description:
  16S rRNA-processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family.


ensembl_gene_id: SBI_03469
symbol: proS2
gene_biotype: protein_coding
description:
  prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).


ensembl_gene_id: SBI_03471
symbol: ffh
gene_biotype: protein_coding
description:
  Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.


ensembl_gene_id: SBI_03477
symbol: ftsY
gene_biotype: protein_coding
description:
  Putative signal recognition particle receptor; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).


ensembl_gene_id: SBI_03483
symbol: SBI_03483
gene_biotype: protein_coding
description:
  Putative glucose transporter; COG0477 Permeases of the major facilitator superfamily; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.


ensembl_gene_id: SBI_03484
symbol: smc
gene_biotype: protein_coding
description:
  Chromosome segregation protein; Required for chromosome condensation and partitioning. Belongs to the SMC family.


ensembl_gene_id: SBI_03489
symbol: mutM2
gene_biotype: protein_coding
description:
  formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.


ensembl_gene_id: SBI_03490
symbol: rnc
gene_biotype: protein_coding
description:
  Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.


ensembl_gene_id: SBI_03494
symbol: coaD
gene_biotype: protein_coding
description:
  Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.


ensembl_gene_id: SBI_03500
symbol: thiL
gene_biotype: protein_coding
description:
  Thiamine monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.


ensembl_gene_id: SBI_03503
symbol: ddl
gene_biotype: protein_coding
description:
  D-alanyl-alanine synthetase A; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.


ensembl_gene_id: SBI_03504
symbol: gpsA
gene_biotype: protein_coding
description:
  COG0240 Glycerol-3-phosphate dehydrogenase; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.


ensembl_gene_id: SBI_03506
symbol: fbiD
gene_biotype: protein_coding
description:
  Hypothetical protein; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.


ensembl_gene_id: SBI_03508
symbol: SBI_03508
gene_biotype: protein_coding
description:
  Putative histone-like DNA binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.


ensembl_gene_id: SBI_03510
symbol: leuD
gene_biotype: protein_coding
description:
  Isopropylmalate isomerase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.


ensembl_gene_id: SBI_03511
symbol: leuC
gene_biotype: protein_coding
description:
  Isopropylmalate isomerase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.


ensembl_gene_id: SBI_03515
symbol: gltX
gene_biotype: protein_coding
description:
  glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.


ensembl_gene_id: SBI_03527
symbol: SBI_03527
gene_biotype: protein_coding
description:
  Putative methylmalonyl-CoA decarboxylase alpha subunit; COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta).


ensembl_gene_id: SBI_03529
symbol: SBI_03529
gene_biotype: protein_coding
description:
  Putative alpha-isopropylmalate/homocitrate synthase family transferase; COG0119 Isopropylmalate/homocitrate/citramalate synthases; Belongs to the alpha-IPM synthase/homocitrate synthase family.


ensembl_gene_id: SBI_03531
symbol: leuB
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.


ensembl_gene_id: SBI_03555
symbol: ilvC
gene_biotype: protein_coding
description:
  Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.


ensembl_gene_id: SBI_03557
symbol: ilvB3
gene_biotype: protein_coding
description:
  Acetolactate synthase 1 catalytic subunit; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase].


ensembl_gene_id: SBI_03572
symbol: gatB
gene_biotype: protein_coding
description:
  aspartyl/glutamyl-tRNA amidotransferase subunit B; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily.


ensembl_gene_id: SBI_03574
symbol: gatA
gene_biotype: protein_coding
description:
  aspartyl/glutamyl-tRNA amidotransferase subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln).


ensembl_gene_id: SBI_03575
symbol: gatC
gene_biotype: protein_coding
description:
  aspartyl/glutamyl-tRNA amidotransferase subunit C; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family.


ensembl_gene_id: SBI_03577
symbol: ligA
gene_biotype: protein_coding
description:
  NAD-dependent DNA ligase LigA; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily.


ensembl_gene_id: SBI_03597
symbol: mnmA
gene_biotype: protein_coding
description:
  tRNA-specific 2-thiouridylase MnmA; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.


ensembl_gene_id: SBI_03598
symbol: SBI_03598
gene_biotype: protein_coding
description:
  Hydride transferase; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: SBI_03600
symbol: SBI_03600
gene_biotype: protein_coding
description:
  Putative aminotransferase; COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes.


ensembl_gene_id: SBI_03605
symbol: SBI_03605
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG4608 ABC-type oligopeptide transport system, ATPase component; Belongs to the ABC transporter superfamily.


ensembl_gene_id: SBI_03606
symbol: SBI_03606
gene_biotype: protein_coding
description:
  Oligopeptide ABC transporter ATP-binding protein; COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component; Belongs to the ABC transporter superfamily.


ensembl_gene_id: SBI_03608
symbol: SBI_03608
gene_biotype: protein_coding
description:
  Oligopeptide-binding lipoprotein; COG0747 ABC-type dipeptide transport system, periplasmic component.


ensembl_gene_id: SBI_03614
symbol: gcvT
gene_biotype: protein_coding
description:
  Glycine cleavage system aminomethyltransferase T; The glycine cleavage system catalyzes the degradation of glycine.


ensembl_gene_id: SBI_03615
symbol: gcvH
gene_biotype: protein_coding
description:
  Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.


ensembl_gene_id: SBI_03636
symbol: SBI_03636
gene_biotype: protein_coding
description:
  D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases.


ensembl_gene_id: SBI_03675
symbol: SBI_03675
gene_biotype: protein_coding
description:
  Putative transcriptional regulator, MerR family protein; COG0789 Predicted transcriptional regulators.


ensembl_gene_id: SBI_03685
symbol: amyA1
gene_biotype: protein_coding
description:
  Alpha-amylase; Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.


ensembl_gene_id: SBI_03688
symbol: glgB
gene_biotype: protein_coding
description:
  Glycogen branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.


ensembl_gene_id: SBI_03695
symbol: dctA2
gene_biotype: protein_coding
description:
  Putative sodium:dicarboxylate symporter; COG1301 Na+/H+-dicarboxylate symporters; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: SBI_03726
symbol: SBI_03726
gene_biotype: protein_coding
description:
  Monooxygenase FAD-binding protein; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.


ensembl_gene_id: SBI_03731
symbol: pfkA1
gene_biotype: protein_coding
description:
  6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.


ensembl_gene_id: SBI_03732
symbol: pta
gene_biotype: protein_coding
description:
  Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.


ensembl_gene_id: SBI_03733
symbol: ackA
gene_biotype: protein_coding
description:
  Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.


ensembl_gene_id: SBI_03752
symbol: SBI_03752
gene_biotype: protein_coding
description:
  LAO/AO transport system ATPase; COG1703 Putative periplasmic protein kinase ArgK and related GTPases of G3E family.


ensembl_gene_id: SBI_03758
symbol: SBI_03758
gene_biotype: protein_coding
description:
  Putative ABC transporter ATP-binding subunit; COG1131 ABC-type multidrug transport system, ATPase component.


ensembl_gene_id: SBI_03761
symbol: SBI_03761
gene_biotype: protein_coding
description:
  Alkanal monooxygenase; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: SBI_03763
symbol: nucS
gene_biotype: protein_coding
description:
  Hypothetical protein; Cleaves both 3' and 5' ssDNA extremities of branched DNA structures; Belongs to the NucS endonuclease family.


ensembl_gene_id: SBI_03765
symbol: SBI_03765
gene_biotype: protein_coding
description:
  COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Belongs to the anti-sigma-factor antagonist family.


ensembl_gene_id: SBI_03768
symbol: SBI_03768
gene_biotype: protein_coding
description:
  ABC transporter, ATP-binding subunit; COG1131 ABC-type multidrug transport system, ATPase component.


ensembl_gene_id: SBI_03769
symbol: SBI_03769
gene_biotype: protein_coding
description:
  Putative ABC transporter integral membrane subunit; COG0842 ABC-type multidrug transport system, permease component.


ensembl_gene_id: SBI_03773
symbol: SBI_03773
gene_biotype: protein_coding
description:
  Putative two-component system response regulator; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: SBI_03775
symbol: atpC
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit epsilon; Produces ATP from ADP in the presence of a proton gradient across the membrane.


ensembl_gene_id: SBI_03776
symbol: atpD
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family.


ensembl_gene_id: SBI_03777
symbol: atpG
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit gamma; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.


ensembl_gene_id: SBI_03779
symbol: atpA
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family.


ensembl_gene_id: SBI_03780
symbol: atpH
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit delta; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family.


ensembl_gene_id: SBI_03781
symbol: atpF
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit B; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family.


ensembl_gene_id: SBI_03782
symbol: atpE
gene_biotype: protein_coding
description:
  F-type proton-transporting ATPase c chain; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.


ensembl_gene_id: SBI_03783
symbol: atpB
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit A; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.


ensembl_gene_id: SBI_03785
symbol: SBI_03785
gene_biotype: protein_coding
description:
  Teichoic acid linkage unit synthesis; COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase.


ensembl_gene_id: SBI_03787
symbol: SBI_03787
gene_biotype: protein_coding
description:
  COG0394 Protein-tyrosine-phosphatase; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.


ensembl_gene_id: SBI_03789
symbol: prmC
gene_biotype: protein_coding
description:
  Putative methyltransferase; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.


ensembl_gene_id: SBI_03790
symbol: prfA
gene_biotype: protein_coding
description:
  Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.


ensembl_gene_id: SBI_03793
symbol: rho
gene_biotype: protein_coding
description:
  Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.


ensembl_gene_id: SBI_03794
symbol: thrB
gene_biotype: protein_coding
description:
  Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.


ensembl_gene_id: SBI_03795
symbol: thrC2
gene_biotype: protein_coding
description:
  Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.


ensembl_gene_id: SBI_03804
symbol: SBI_03804
gene_biotype: protein_coding
description:
  Restriction modification system DNA specificity subunit; COG0732 Restriction endonuclease S subunits.


ensembl_gene_id: SBI_03807
symbol: SBI_03807
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0610 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases.


ensembl_gene_id: SBI_03809
symbol: SBI_03809
gene_biotype: protein_coding
description:
  DNA-binding protein; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: SBI_03827
symbol: SBI_03827
gene_biotype: protein_coding
description:
  ABC transporter related protein; COG1136 ABC-type antimicrobial peptide transport system, ATPase component.


ensembl_gene_id: SBI_03864
symbol: SBI_03864
gene_biotype: protein_coding
description:
  NLP/P60 family secreted protein; COG0791 Cell wall-associated hydrolases (invasion-associated proteins).


ensembl_gene_id: SBI_03873
symbol: lon
gene_biotype: protein_coding
description:
  ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.


ensembl_gene_id: SBI_03876
symbol: SBI_03876
gene_biotype: protein_coding
description:
  Putative ABC transporter ATP-binding protein; COG1131 ABC-type multidrug transport system, ATPase component.


ensembl_gene_id: SBI_03883
symbol: kgd
gene_biotype: protein_coding
description:
  Alpha-ketoglutarate decarboxylase; COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes.


ensembl_gene_id: SBI_03890
symbol: SBI_03890
gene_biotype: protein_coding
description:
  protein-L-isoaspartate-O-methyltransferase; COG2518 Protein-L-isoaspartate carboxylmethyltransferase.


ensembl_gene_id: SBI_03909
symbol: fabG
gene_biotype: protein_coding
description:
  3-ketoacyl-(acyl-carrier-protein) reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: SBI_03913
symbol: SBI_03913
gene_biotype: protein_coding
description:
  SARP family pathway specific regulatory protein; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: SBI_03925
symbol: SBI_03925
gene_biotype: protein_coding
description:
  Arginine/ornithine binding protein; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain.


ensembl_gene_id: SBI_03927
symbol: SBI_03927
gene_biotype: protein_coding
description:
  Phosphate ABC transporter ATP-binding protein; COG1126 ABC-type polar amino acid transport system, ATPase component.


ensembl_gene_id: SBI_03944
symbol: SBI_03944
gene_biotype: protein_coding
description:
  Putative anti-anti-sigma-factor; COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Belongs to the anti-sigma-factor antagonist family.


ensembl_gene_id: SBI_03947
symbol: fabH-2
gene_biotype: protein_coding
description:
  3-oxoacyl-(acyl-carrier-protein) synthase 3; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.


ensembl_gene_id: SBI_03953
symbol: SBI_03953
gene_biotype: protein_coding
description:
  Na+/H+ antiporter; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.


ensembl_gene_id: SBI_03956
symbol: SBI_03956
gene_biotype: protein_coding
description:
  Putative sigma factor; COG1191 DNA-directed RNA polymerase specialized sigma subunit; Belongs to the sigma-70 factor family.


ensembl_gene_id: SBI_03959
symbol: whiB
gene_biotype: protein_coding
description:
  WhiB-family transcriptional regulator; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.


ensembl_gene_id: SBI_03963
symbol: SBI_03963
gene_biotype: protein_coding
description:
  Sugar transporter integral membrane protein; COG0395 ABC-type sugar transport system, permease component.


ensembl_gene_id: SBI_03964
symbol: SBI_03964
gene_biotype: protein_coding
description:
  Sugar transporter integral membrane protein; COG1175 ABC-type sugar transport systems, permease components.


ensembl_gene_id: SBI_03965
symbol: SBI_03965
gene_biotype: protein_coding
description:
  Sugar transporter sugar binding protein; COG1653 ABC-type sugar transport system, periplasmic component.


ensembl_gene_id: SBI_03977
symbol: SBI_03977
gene_biotype: protein_coding
description:
  Beta-lactamase domain-containing protein; COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III.


ensembl_gene_id: SBI_03982
symbol: SBI_03982
gene_biotype: protein_coding
description:
  Putative channel transporter; COG0580 Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family); Belongs to the MIP/aquaporin (TC 1.A.8) family.


ensembl_gene_id: SBI_03999
symbol: SBI_03999
gene_biotype: protein_coding
description:
  2-hydroxyacid family dehydrogenase; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: SBI_04001
symbol: SBI_04001
gene_biotype: protein_coding
description:
  Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.


ensembl_gene_id: SBI_04002
symbol: SBI_04002
gene_biotype: protein_coding
description:
  Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.


ensembl_gene_id: SBI_04005
symbol: def-2
gene_biotype: protein_coding
description:
  Polypeptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.


ensembl_gene_id: SBI_04014
symbol: aroA
gene_biotype: protein_coding
description:
  3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.


ensembl_gene_id: SBI_04015
symbol: rsgA-2
gene_biotype: protein_coding
description:
  Hypothetical protein; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.


ensembl_gene_id: SBI_04018
symbol: SBI_04018
gene_biotype: protein_coding
description:
  COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family.


ensembl_gene_id: SBI_04020
symbol: SBI_04020
gene_biotype: protein_coding
description:
  Hydrogen peroxide sensitive repressor; COG0735 Fe2+/Zn2+ uptake regulation proteins; Belongs to the Fur family.


ensembl_gene_id: SBI_04026
symbol: SBI_04026
gene_biotype: protein_coding
description:
  Putative molybdopterin biosynthesis protein E; COG0314 Molybdopterin converting factor, large subunit.


ensembl_gene_id: SBI_04029
symbol: SBI_04029
gene_biotype: protein_coding
description:
  Putative NUDIX hydrolase; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes.


ensembl_gene_id: SBI_04037
symbol: whiB-2
gene_biotype: protein_coding
description:
  Putative DNA-binding protein; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.


ensembl_gene_id: SBI_04044
symbol: SBI_04044
gene_biotype: protein_coding
description:
  Hypothetical protein; COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding.


ensembl_gene_id: SBI_04045
symbol: SBI_04045
gene_biotype: protein_coding
description:
  Peptidase; COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases.


ensembl_gene_id: SBI_04052
symbol: SBI_04052
gene_biotype: protein_coding
description:
  Molybdopterin biosynthesis-like protein MoeZ; COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2.


ensembl_gene_id: SBI_04077
symbol: SBI_04077
gene_biotype: protein_coding
description:
  ATP-binding protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.


ensembl_gene_id: SBI_04079
symbol: tatB
gene_biotype: protein_coding
description:
  Sec-independent translocase; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.


ensembl_gene_id: SBI_04088
symbol: folP1
gene_biotype: protein_coding
description:
  Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.


ensembl_gene_id: SBI_04097
symbol: SBI_04097
gene_biotype: protein_coding
description:
  ABC transporter integral membrane protein; COG0842 ABC-type multidrug transport system, permease component.


ensembl_gene_id: SBI_04101
symbol: mshB
gene_biotype: protein_coding
description:
  Putative N-acetyl-1-D-myo-inosityl-2-amino-2- deoxy-alpha-D-glucopyranoside deacetylase; Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2- deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.


ensembl_gene_id: SBI_04105
symbol: SBI_04105
gene_biotype: protein_coding
description:
  ABC transporter integral membrane protein; COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components.


ensembl_gene_id: SBI_04107
symbol: SBI_04107
gene_biotype: protein_coding
description:
  BldKC, ABC transport system integral membrane protein; COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components.


ensembl_gene_id: SBI_04108
symbol: SBI_04108
gene_biotype: protein_coding
description:
  BldKD putative oligopeptide ABC transporter subunit; COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component; Belongs to the ABC transporter superfamily.


ensembl_gene_id: SBI_04112
symbol: SBI_04112
gene_biotype: protein_coding
description:
  Carbohydrate ABC transporter membrane protein; COG1175 ABC-type sugar transport systems, permease components.


ensembl_gene_id: SBI_04114
symbol: SBI_04114
gene_biotype: protein_coding
description:
  Extracellular solute-binding protein; COG1653 ABC-type sugar transport system, periplasmic component.


ensembl_gene_id: SBI_04116
symbol: SBI_04116
gene_biotype: protein_coding
description:
  Putative peptide ABC transporter ATP-binding protein; COG4608 ABC-type oligopeptide transport system, ATPase component; Belongs to the ABC transporter superfamily.


ensembl_gene_id: SBI_04117
symbol: SBI_04117
gene_biotype: protein_coding
description:
  Peptide ABC transporter ATP-binding protein; COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component; Belongs to the ABC transporter superfamily.


ensembl_gene_id: SBI_04118
symbol: SBI_04118
gene_biotype: protein_coding
description:
  Putative transporter substrate-binding protein; COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components.


ensembl_gene_id: SBI_04119
symbol: SBI_04119
gene_biotype: protein_coding
description:
  Oligopeptide ABC transporter substrate-binding protein; COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components.


ensembl_gene_id: SBI_04120
symbol: SBI_04120
gene_biotype: protein_coding
description:
  Putative transporter peptide-binding protein; COG4166 ABC-type oligopeptide transport system, periplasmic component.


ensembl_gene_id: SBI_04130
symbol: SBI_04130
gene_biotype: protein_coding
description:
  Putative peptide ABC transporter ATP-binding protein; COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component; Belongs to the ABC transporter superfamily.


ensembl_gene_id: SBI_04133
symbol: SBI_04133
gene_biotype: protein_coding
description:
  Putative peptide ABC transporter substrate-binding protein; COG4166 ABC-type oligopeptide transport system, periplasmic component.


ensembl_gene_id: SBI_04134
symbol: SBI_04134
gene_biotype: protein_coding
description:
  Putative GTP-binding elongation factor; COG1217 Predicted membrane GTPase involved in stress response.


ensembl_gene_id: SBI_04143
symbol: SBI_04143
gene_biotype: protein_coding
description:
  Putative NUDIX hydrolase; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; Belongs to the Nudix hydrolase family.


ensembl_gene_id: SBI_04155
symbol: ychF
gene_biotype: protein_coding
description:
  GTP-dependent nucleic acid-binding protein EngD; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.


ensembl_gene_id: SBI_04158
symbol: ispH
gene_biotype: protein_coding
description:
  4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.


ensembl_gene_id: SBI_04159
symbol: xseA
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family.


ensembl_gene_id: SBI_04160
symbol: xseB
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.


ensembl_gene_id: SBI_04166
symbol: SBI_04166
gene_biotype: protein_coding
description:
  Fumarate hydratase class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.


ensembl_gene_id: SBI_04170
symbol: fumC-2
gene_biotype: protein_coding
description:
  Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.


ensembl_gene_id: SBI_04179
symbol: SBI_04179
gene_biotype: protein_coding
description:
  Integral membrane protein; COG0577 ABC-type antimicrobial peptide transport system, permease component.


ensembl_gene_id: SBI_04183
symbol: ahpD
gene_biotype: protein_coding
description:
  Alkylhydroperoxidase; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.


ensembl_gene_id: SBI_04186
symbol: SBI_04186
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains).


ensembl_gene_id: SBI_04187
symbol: SBI_04187
gene_biotype: protein_coding
description:
  Putative ATP-binding protein; COG1875 Predicted ATPase related to phosphate starvation-inducible protein PhoH.


ensembl_gene_id: SBI_04188
symbol: SBI_04188
gene_biotype: protein_coding
description:
  Putative undecaprenyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.


ensembl_gene_id: SBI_04234
symbol: SBI_04234
gene_biotype: protein_coding
description:
  Peptide ABC transporter, ATP-binding protein; COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase; Belongs to the ABC transporter superfamily.


ensembl_gene_id: SBI_04237
symbol: SBI_04237
gene_biotype: protein_coding
description:
  ABC peptide transporter binding protein; COG0747 ABC-type dipeptide transport system, periplasmic component.


ensembl_gene_id: SBI_04242
symbol: SBI_04242
gene_biotype: protein_coding
description:
  COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family.


ensembl_gene_id: SBI_04247
symbol: SBI_04247
gene_biotype: protein_coding
description:
  Indoleacetamide hydrolase; COG0154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases; Belongs to the amidase family.


ensembl_gene_id: SBI_04252
symbol: SBI_04252
gene_biotype: protein_coding
description:
  NAD-dependent glycerol-3-phosphate dehydrogenase; COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases.


ensembl_gene_id: SBI_04255
symbol: SBI_04255
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs.


ensembl_gene_id: SBI_04261
symbol: pckG
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.


ensembl_gene_id: SBI_04268
symbol: mca
gene_biotype: protein_coding
description:
  Mycothiol conjugate amidase Mca; A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S- conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics; Belongs to the MshB deacetylase family. Mca subfamily.


ensembl_gene_id: SBI_04270
symbol: greA
gene_biotype: protein_coding
description:
  Transcription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.


ensembl_gene_id: SBI_04279
symbol: msrA
gene_biotype: protein_coding
description:
  Peptide-methionine (S)-S-oxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.


ensembl_gene_id: SBI_04314
symbol: mfd
gene_biotype: protein_coding
description:
  Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.


ensembl_gene_id: SBI_04318
symbol: SBI_04318
gene_biotype: protein_coding
description:
  Hypothetical protein; COG2026 Cytotoxic translational repressor of toxin-antitoxin stability system.


ensembl_gene_id: SBI_04333
symbol: SBI_04333
gene_biotype: protein_coding
description:
  Gas vesicle synthesis protein; COG1241 Predicted ATPase involved in replication control, Cdc46/Mcm family.


ensembl_gene_id: SBI_04336
symbol: argJ-2
gene_biotype: protein_coding
description:
  N-acetylglutamate synthase /glutamate N-acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.


ensembl_gene_id: SBI_04346
symbol: glmU
gene_biotype: protein_coding
description:
  Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.


ensembl_gene_id: SBI_04347
symbol: prsA
gene_biotype: protein_coding
description:
  Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.


ensembl_gene_id: SBI_04348
symbol: rplY
gene_biotype: protein_coding
description:
  50S ribosomal protein L25/general stress protein Ctc; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.


ensembl_gene_id: SBI_04349
symbol: pth
gene_biotype: protein_coding
description:
  peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.


ensembl_gene_id: SBI_04351
symbol: ppc
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family.


ensembl_gene_id: SBI_04357
symbol: tam
gene_biotype: protein_coding
description:
  Trans-aconitate 2-methyltransferase; Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.


ensembl_gene_id: SBI_04360
symbol: galK
gene_biotype: protein_coding
description:
  Galactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily.


ensembl_gene_id: SBI_04363
symbol: SBI_04363
gene_biotype: protein_coding
description:
  Na+/galactose cotransporter; COG4146 Predicted symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: SBI_04369
symbol: cmeK
gene_biotype: protein_coding
description:
  4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.


ensembl_gene_id: SBI_04370
symbol: ksgA
gene_biotype: protein_coding
description:
  Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.


ensembl_gene_id: SBI_04374
symbol: rsmI
gene_biotype: protein_coding
description:
  Tetrapyrrole methylase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.


ensembl_gene_id: SBI_04384
symbol: SBI_04384
gene_biotype: protein_coding
description:
  Hypothetical protein; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: SBI_04393
symbol: SBI_04393
gene_biotype: protein_coding
description:
  Putative ABC transporter ATP-binding protein; Part of an ABC transporter complex. Responsible for energy coupling to the transport system.


ensembl_gene_id: SBI_04394
symbol: SBI_04394
gene_biotype: protein_coding
description:
  Putative cobalt transporter; COG0619 ABC-type cobalt transport system, permease component CbiQ and related transporters.


ensembl_gene_id: SBI_04398
symbol: SBI_04398
gene_biotype: protein_coding
description:
  Putative protease; COG4946 Uncharacterized protein related to the periplasmic component of the Tol biopolymer transport system.


ensembl_gene_id: SBI_04413
symbol: SBI_04413
gene_biotype: protein_coding
description:
  NADPH:quinone reductase and related Zn-dependent oxidoreductase-like protein; COG0702 Predicted nucleoside-diphosphate-sugar epimerases.


ensembl_gene_id: SBI_04420
symbol: SBI_04420
gene_biotype: protein_coding
description:
  Putative sugar transporter, permease protein; COG0395 ABC-type sugar transport system, permease component.


ensembl_gene_id: SBI_04448
symbol: SBI_04448
gene_biotype: protein_coding
description:
  Dehydrogenase; COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases.


ensembl_gene_id: SBI_04452
symbol: ahcY
gene_biotype: protein_coding
description:
  S-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.


ensembl_gene_id: SBI_04453
symbol: SBI_04453
gene_biotype: protein_coding
description:
  PTS system, fructose subfamily, IIC subunit; COG1445 Phosphotransferase system fructose-specific component IIB.


ensembl_gene_id: SBI_04463
symbol: whiB-3
gene_biotype: protein_coding
description:
  WhiB family transcriptional regulator; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.


ensembl_gene_id: SBI_04464
symbol: SBI_04464
gene_biotype: protein_coding
description:
  Putative cysteine dioxygenase; COG1917 Uncharacterized conserved protein, contains double-stranded beta-helix domain.


ensembl_gene_id: SBI_04465
symbol: fbiA
gene_biotype: protein_coding
description:
  LPPG:FO 2-phospho-L-lactate transferase; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP.


ensembl_gene_id: SBI_04466
symbol: fbiB
gene_biotype: protein_coding
description:
  F420-O-gamma-glutamyl ligase; Bifunctional enzyme that catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L- lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives, and the FMNH2- dependent reduction of dehydro-F420-0 to form F420-0.


ensembl_gene_id: SBI_04468
symbol: SBI_04468
gene_biotype: protein_coding
description:
  Putative ABC transporter permease protein; COG0765 ABC-type amino acid transport system, permease component.


ensembl_gene_id: SBI_04481
symbol: SBI_04481
gene_biotype: protein_coding
description:
  ABC transporter, nucleotide binding/ATPase protein; COG1136 ABC-type antimicrobial peptide transport system, ATPase component.


ensembl_gene_id: SBI_04491
symbol: SBI_04491
gene_biotype: protein_coding
description:
  RNA polymerase sigma-24 subunit, ECF subfamily protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: SBI_04494
symbol: SBI_04494
gene_biotype: protein_coding
description:
  Nucleotide phosphorylase; COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon).


ensembl_gene_id: SBI_04513
symbol: purE
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).


ensembl_gene_id: SBI_04514
symbol: purK
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazole carboxylase ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).


ensembl_gene_id: SBI_04530
symbol: SBI_04530
gene_biotype: protein_coding
description:
  SigL-like sigma factor; COG1191 DNA-directed RNA polymerase specialized sigma subunit; Belongs to the sigma-70 factor family.


ensembl_gene_id: SBI_04533
symbol: SBI_04533
gene_biotype: protein_coding
description:
  N-formimino-L-glutamate deiminase; COG0402 Cytosine deaminase and related metal-dependent hydrolases.


ensembl_gene_id: SBI_04542
symbol: SBI_04542
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG1125 ABC-type proline/glycine betaine transport systems, ATPase components.


ensembl_gene_id: SBI_04543
symbol: SBI_04543
gene_biotype: protein_coding
description:
  ABC transporter permease; COG1174 ABC-type proline/glycine betaine transport systems, permease component.


ensembl_gene_id: SBI_04545
symbol: SBI_04545
gene_biotype: protein_coding
description:
  COG1732 Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein).


ensembl_gene_id: SBI_04556
symbol: SBI_04556
gene_biotype: protein_coding
description:
  ABC transporter integral membrane protein; COG0577 ABC-type antimicrobial peptide transport system, permease component.


ensembl_gene_id: SBI_04562
symbol: eno
gene_biotype: protein_coding
description:
  Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.


ensembl_gene_id: SBI_04577
symbol: savM
gene_biotype: protein_coding
description:
  Type II restriction-modification system DNA adenine-specific methylase; COG0286 Type I restriction-modification system methyltransferase subunit.


ensembl_gene_id: SBI_04601
symbol: SBI_04601
gene_biotype: protein_coding
description:
  Putative acyl-CoA carboxylase beta subunit; COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta).


ensembl_gene_id: SBI_04607
symbol: SBI_04607
gene_biotype: protein_coding
description:
  Putative oligopeptide ABC transporter, ATP-binding protein; COG1136 ABC-type antimicrobial peptide transport system, ATPase component.


ensembl_gene_id: SBI_04608
symbol: SBI_04608
gene_biotype: protein_coding
description:
  ABC transporter permease; COG0577 ABC-type antimicrobial peptide transport system, permease component.


ensembl_gene_id: SBI_04609
symbol: SBI_04609
gene_biotype: protein_coding
description:
  Putative Maf-like protein protein; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.


ensembl_gene_id: SBI_04616
symbol: SBI_04616
gene_biotype: protein_coding
description:
  Flavoprotein disulfide reductase; COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes.


ensembl_gene_id: SBI_04618
symbol: SBI_04618
gene_biotype: protein_coding
description:
  Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.


ensembl_gene_id: SBI_04635
symbol: lspA
gene_biotype: protein_coding
description:
  Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.


ensembl_gene_id: SBI_04638
symbol: SBI_04638
gene_biotype: protein_coding
description:
  Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate.


ensembl_gene_id: SBI_04642
symbol: sig21
gene_biotype: protein_coding
description:
  Putative sigma factor; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: SBI_04648
symbol: add2
gene_biotype: protein_coding
description:
  COG1816 Adenosine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.


ensembl_gene_id: SBI_04654
symbol: SBI_04654
gene_biotype: protein_coding
description:
  Putative sugar ABC transporter permease protein; COG1079 Uncharacterized ABC-type transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: SBI_04655
symbol: SBI_04655
gene_biotype: protein_coding
description:
  Putative sugar ABC transporter permease protein; COG4603 ABC-type uncharacterized transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: SBI_04657
symbol: SBI_04657
gene_biotype: protein_coding
description:
  Putative lipoprotein; COG1744 Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein.


ensembl_gene_id: SBI_04677
symbol: SBI_04677
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1804 Predicted acyl-CoA transferases/carnitine dehydratase; Belongs to the CoA-transferase III family.


ensembl_gene_id: SBI_04682
symbol: SBI_04682
gene_biotype: protein_coding
description:
  5-keto-D-gluconate 5-reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: SBI_04686
symbol: SBI_04686
gene_biotype: protein_coding
description:
  Amidase; COG0154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases; Belongs to the amidase family.


ensembl_gene_id: SBI_04711
symbol: sdhB
gene_biotype: protein_coding
description:
  COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.


ensembl_gene_id: SBI_04722
symbol: trpS
gene_biotype: protein_coding
description:
  tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: SBI_04742
symbol: SBI_04742
gene_biotype: protein_coding
description:
  Glycine betaine-binding lipoprotein; COG2113 ABC-type proline/glycine betaine transport systems, periplasmic components.


ensembl_gene_id: SBI_04743
symbol: SBI_04743
gene_biotype: protein_coding
description:
  Glycine betaine ABC transporter integral membrane protein; COG4176 ABC-type proline/glycine betaine transport system, permease component.


ensembl_gene_id: SBI_04744
symbol: SBI_04744
gene_biotype: protein_coding
description:
  Putative glycine betaine ABC transporter ATP-binding protein; COG4175 ABC-type proline/glycine betaine transport system, ATPase component.


ensembl_gene_id: SBI_04749
symbol: mdh
gene_biotype: protein_coding
description:
  Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.


ensembl_gene_id: SBI_04754
symbol: folD
gene_biotype: protein_coding
description:
  Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.


ensembl_gene_id: SBI_04755
symbol: purH
gene_biotype: protein_coding
description:
  Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful).


ensembl_gene_id: SBI_04756
symbol: purN
gene_biotype: protein_coding
description:
  Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.


ensembl_gene_id: SBI_04768
symbol: icmB
gene_biotype: protein_coding
description:
  Putative isobutyryl-CoA mutase, chain B; COG2185 Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding).


ensembl_gene_id: SBI_04778
symbol: SBI_04778
gene_biotype: protein_coding
description:
  (S)-2-hydroxy-acid oxidase; COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases.


ensembl_gene_id: SBI_04790
symbol: SBI_04790
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases.


ensembl_gene_id: SBI_04802
symbol: gabD2
gene_biotype: protein_coding
description:
  Succinic semialdehyde dehydrogenase; COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: SBI_04812
symbol: SBI_04812
gene_biotype: protein_coding
description:
  Putative ABC transporter integral membrane protein; COG0842 ABC-type multidrug transport system, permease component.


ensembl_gene_id: SBI_04823
symbol: SBI_04823
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0190 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase.


ensembl_gene_id: SBI_04832
symbol: SBI_04832
gene_biotype: protein_coding
description:
  Secreted peptidase; COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains).


ensembl_gene_id: SBI_04837
symbol: purU
gene_biotype: protein_coding
description:
  Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).


ensembl_gene_id: SBI_04865
symbol: SBI_04865
gene_biotype: protein_coding
description:
  COG4821 Uncharacterized protein containing SIS (Sugar ISomerase) phosphosugar binding domain; Belongs to the UPF0309 family.


ensembl_gene_id: SBI_04867
symbol: pdxH
gene_biotype: protein_coding
description:
  Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).


ensembl_gene_id: SBI_04890
symbol: serC
gene_biotype: protein_coding
description:
  Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.


ensembl_gene_id: SBI_04897
symbol: SBI_04897
gene_biotype: protein_coding
description:
  Putative sugar-phosphate dehydrogenase; COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases).


ensembl_gene_id: SBI_04898
symbol: SBI_04898
gene_biotype: protein_coding
description:
  Hypothetical protein; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family.


ensembl_gene_id: SBI_04910
symbol: SBI_04910
gene_biotype: protein_coding
description:
  COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.


ensembl_gene_id: SBI_04915
symbol: mqnB
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2).


ensembl_gene_id: SBI_04916
symbol: mqnD
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily.


ensembl_gene_id: SBI_04945
symbol: murQ
gene_biotype: protein_coding
description:
  N-acetylmuramic acid-6-phosphate etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate.


ensembl_gene_id: SBI_04946
symbol: groEL
gene_biotype: protein_coding
description:
  Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.


ensembl_gene_id: SBI_04950
symbol: SBI_04950
gene_biotype: protein_coding
description:
  Putative glucosyl-3-phosphoglycerate synthase; COG0463 Glycosyltransferases involved in cell wall biogenesis.


ensembl_gene_id: SBI_04952
symbol: otsB
gene_biotype: protein_coding
description:
  Trehalose-6-phosphatase; Removes the phosphate from trehalose 6-phosphate to produce free trehalose.


ensembl_gene_id: SBI_04954
symbol: SBI_04954
gene_biotype: protein_coding
description:
  Putative secreted solute-binding protein; COG1653 ABC-type sugar transport system, periplasmic component.


ensembl_gene_id: SBI_04957
symbol: SBI_04957
gene_biotype: protein_coding
description:
  Sugar kinase; COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); Belongs to the carbohydrate kinase PfkB family.


ensembl_gene_id: SBI_04960
symbol: SBI_04960
gene_biotype: protein_coding
description:
  Reductase; COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family.


ensembl_gene_id: SBI_04961
symbol: SBI_04961
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1393 Arsenate reductase and related proteins, glutaredoxin family; Belongs to the ArsC family.


ensembl_gene_id: SBI_04963
symbol: SBI_04963
gene_biotype: protein_coding
description:
  Putative TerD-family protein; COG2310 Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1.


ensembl_gene_id: SBI_04967
symbol: SBI_04967
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: SBI_04983
symbol: SBI_04983
gene_biotype: protein_coding
description:
  Putative maltose/cellubiose ABC transporter ATP-binding subunit; COG3839 ABC-type sugar transport systems, ATPase components; Belongs to the ABC transporter superfamily.


ensembl_gene_id: SBI_04985
symbol: SBI_04985
gene_biotype: protein_coding
description:
  Guanyltransferase; COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon).


ensembl_gene_id: SBI_04987
symbol: SBI_04987
gene_biotype: protein_coding
description:
  Putative RNA methyltransferase; COG0566 rRNA methylases; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.


ensembl_gene_id: SBI_04989
symbol: ispF
gene_biotype: protein_coding
description:
  2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).


ensembl_gene_id: SBI_04990
symbol: ispD
gene_biotype: protein_coding
description:
  2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).


ensembl_gene_id: SBI_04997
symbol: SBI_04997
gene_biotype: protein_coding
description:
  Haloalkane dehalogenase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: SBI_05009
symbol: mshA
gene_biotype: protein_coding
description:
  Glycosyl transferase; Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2- deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.


ensembl_gene_id: SBI_05017
symbol: ppk
gene_biotype: protein_coding
description:
  Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family.


ensembl_gene_id: SBI_05018
symbol: mshD
gene_biotype: protein_coding
description:
  Acetyltransferase; Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.


ensembl_gene_id: SBI_05019
symbol: SBI_05019
gene_biotype: protein_coding
description:
  COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family.


ensembl_gene_id: SBI_05049
symbol: SBI_05049
gene_biotype: protein_coding
description:
  Protease; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain.


ensembl_gene_id: SBI_05054
symbol: SBI_05054
gene_biotype: protein_coding
description:
  Putative ABC transporter; COG1132 ABC-type multidrug transport system, ATPase and permease components.


ensembl_gene_id: SBI_05065
symbol: SBI_05065
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0354 Predicted aminomethyltransferase related to GcvT; Belongs to the GcvT family.


ensembl_gene_id: SBI_05066
symbol: dtd
gene_biotype: protein_coding
description:
  D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family.


ensembl_gene_id: SBI_05068
symbol: SBI_05068
gene_biotype: protein_coding
description:
  Hypothetical protein; COG4552 Predicted acetyltransferase involved in intracellular survival and related acetyltransferases.


ensembl_gene_id: SBI_05094
symbol: SBI_05094
gene_biotype: protein_coding
description:
  NLP/P60-family secreted protein; COG0791 Cell wall-associated hydrolases (invasion-associated proteins).


ensembl_gene_id: SBI_05095
symbol: SBI_05095
gene_biotype: protein_coding
description:
  Putative high-affinity phosphate-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import; Belongs to the PstS family.


ensembl_gene_id: SBI_05096
symbol: SBI_05096
gene_biotype: protein_coding
description:
  Phosphate transporter permease subunit PstC; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: SBI_05098
symbol: pstB
gene_biotype: protein_coding
description:
  Phosphate transporter ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.


ensembl_gene_id: SBI_05106
symbol: SBI_05106
gene_biotype: protein_coding
description:
  COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains).


ensembl_gene_id: SBI_05116
symbol: SBI_05116
gene_biotype: protein_coding
description:
  Lantibiotic transport ATP-binding protein; COG1131 ABC-type multidrug transport system, ATPase component.


ensembl_gene_id: SBI_05122
symbol: asd
gene_biotype: protein_coding
description:
  Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.


ensembl_gene_id: SBI_05125
symbol: recR
gene_biotype: protein_coding
description:
  Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.


ensembl_gene_id: SBI_05126
symbol: SBI_05126
gene_biotype: protein_coding
description:
  Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.


ensembl_gene_id: SBI_05142
symbol: traSA1
gene_biotype: protein_coding
description:
  Putative plasmid transfer protein; COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins.


ensembl_gene_id: SBI_05145
symbol: SBI_05145
gene_biotype: protein_coding
description:
  MutT-like protein; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; Belongs to the Nudix hydrolase family.


ensembl_gene_id: SBI_05159
symbol: SBI_05159
gene_biotype: protein_coding
description:
  Putative phenylacetic acid degradation protein; COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism.


ensembl_gene_id: SBI_05165
symbol: SBI_05165
gene_biotype: protein_coding
description:
  Glycosyl hydrolase family 32 domain protein; COG1621 Beta-fructosidases (levanase/invertase); Belongs to the glycosyl hydrolase 32 family.


ensembl_gene_id: SBI_05168
symbol: SBI_05168
gene_biotype: protein_coding
description:
  Extracellular solute-binding domain-containing protein; COG1653 ABC-type sugar transport system, periplasmic component.


ensembl_gene_id: SBI_05169
symbol: SBI_05169
gene_biotype: protein_coding
description:
  Levanase; COG1621 Beta-fructosidases (levanase/invertase); Belongs to the glycosyl hydrolase 32 family.


ensembl_gene_id: SBI_05189
symbol: SBI_05189
gene_biotype: protein_coding
description:
  Putative ABC transporter ATP-binding protein; COG1136 ABC-type antimicrobial peptide transport system, ATPase component.


ensembl_gene_id: SBI_05201
symbol: SBI_05201
gene_biotype: protein_coding
description:
  Extracellular solute-binding protein family 1; COG0687 Spermidine/putrescine-binding periplasmic protein.


ensembl_gene_id: SBI_05202
symbol: SBI_05202
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1176 ABC-type spermidine/putrescine transport system, permease component I.


ensembl_gene_id: SBI_05208
symbol: SBI_05208
gene_biotype: protein_coding
description:
  Putative polyprenyl diphosphate synthase; COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.


ensembl_gene_id: SBI_05218
symbol: upp
gene_biotype: protein_coding
description:
  Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.


ensembl_gene_id: SBI_05220
symbol: tadA
gene_biotype: protein_coding
description:
  Cytidine/deoxycytidine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.


ensembl_gene_id: SBI_05228
symbol: pfkA2
gene_biotype: protein_coding
description:
  6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.


ensembl_gene_id: SBI_05239
symbol: SBI_05239
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family.


ensembl_gene_id: SBI_05280
symbol: SBI_05280
gene_biotype: protein_coding
description:
  Putative gntR family regulator; COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs.


ensembl_gene_id: SBI_05284
symbol: SBI_05284
gene_biotype: protein_coding
description:
  COG1999 Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems.


ensembl_gene_id: SBI_05286
symbol: SBI_05286
gene_biotype: protein_coding
description:
  Putative integral membrane protein; COG2372 Uncharacterized protein, homolog of Cu resistance protein CopC.


ensembl_gene_id: SBI_05287
symbol: SBI_05287
gene_biotype: protein_coding
description:
  Putative Dyp-type peroxidase family protein; Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the tetrapyrrol ring intact. Belongs to the DyP-type peroxidase family.


ensembl_gene_id: SBI_05289
symbol: serS1
gene_biotype: protein_coding
description:
  seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).


ensembl_gene_id: SBI_05295
symbol: SBI_05295
gene_biotype: protein_coding
description:
  Putative ABC transporter permease protein; COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component.


ensembl_gene_id: SBI_05309
symbol: htpX1
gene_biotype: protein_coding
description:
  Heat shock protein HtpX; COG0501 Zn-dependent protease with chaperone function; Belongs to the peptidase M48B family.


ensembl_gene_id: SBI_05314
symbol: SBI_05314
gene_biotype: protein_coding
description:
  COG4988 ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components.


ensembl_gene_id: SBI_05317
symbol: hisC3
gene_biotype: protein_coding
description:
  Putative aminotransferase; May catalyze the transamination reaction in phenylalanine biosynthesis; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: SBI_05327
symbol: thiC
gene_biotype: protein_coding
description:
  Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.


ensembl_gene_id: SBI_05333
symbol: SBI_05333
gene_biotype: protein_coding
description:
  Low molecular weight protein-tyrosine-phosphatase; COG0394 Protein-tyrosine-phosphatase; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.


ensembl_gene_id: SBI_05337
symbol: SBI_05337
gene_biotype: protein_coding
description:
  Hypothetical protein; COG3576 Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase.


ensembl_gene_id: SBI_05349
symbol: def-3
gene_biotype: protein_coding
description:
  Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.


ensembl_gene_id: SBI_05351
symbol: dnaB
gene_biotype: protein_coding
description:
  Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily.


ensembl_gene_id: SBI_05366
symbol: SBI_05366
gene_biotype: protein_coding
description:
  COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.


ensembl_gene_id: SBI_05377
symbol: gidB
gene_biotype: protein_coding
description:
  16S rRNA methyltransferase GidB; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.


ensembl_gene_id: SBI_05379
symbol: SBI_05379
gene_biotype: protein_coding
description:
  Putative inner membrane protein translocase component YidC; COG0706 Preprotein translocase subunit YidC.


ensembl_gene_id: SBI_05380
symbol: SBI_05380
gene_biotype: protein_coding
description:
  Hypothetical protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family.


ensembl_gene_id: SBI_05381
symbol: rnpA
gene_biotype: protein_coding
description:
  RNase P component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.


ensembl_gene_id: SBI_05383
symbol: dnaA
gene_biotype: protein_coding
description:
  Chromosomal replication initiation protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.


ensembl_gene_id: SBI_05384
symbol: dnaN
gene_biotype: protein_coding
description:
  DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of  [...]


ensembl_gene_id: SBI_05386
symbol: recF
gene_biotype: protein_coding
description:
  Recombination protein F; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family.


ensembl_gene_id: SBI_05387
symbol: SBI_05387
gene_biotype: protein_coding
description:
  Hypothetical protein; COG5512 Zn-ribbon-containing, possibly RNA-binding protein and truncated derivatives; Belongs to the UPF0232 family.


ensembl_gene_id: SBI_05388
symbol: gyrB
gene_biotype: protein_coding
description:
  DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.


ensembl_gene_id: SBI_05389
symbol: gyrA
gene_biotype: protein_coding
description:
  DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.


ensembl_gene_id: SBI_05397
symbol: SBI_05397
gene_biotype: protein_coding
description:
  Putative peptidylprolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.


ensembl_gene_id: SBI_05412
symbol: azoR
gene_biotype: protein_coding
description:
  Putative dehydrogenase flavoprotein; Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity; Belongs to the azoreductase type 1 family.


ensembl_gene_id: SBI_05418
symbol: paaE
gene_biotype: protein_coding
description:
  Phenylacetic acid degradation NADH oxidoreductase; COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1.


ensembl_gene_id: SBI_05419
symbol: paaD
gene_biotype: protein_coding
description:
  Putative phenylacetic acid degradation protein; COG2151 Predicted metal-sulfur cluster biosynthetic enzyme.


ensembl_gene_id: SBI_05421
symbol: paaB
gene_biotype: protein_coding
description:
  phenylacetate-CoA oxygenase subunit PaaB; COG3460 Uncharacterized enzyme of phenylacetate metabolism.


ensembl_gene_id: SBI_05430
symbol: SBI_05430
gene_biotype: protein_coding
description:
  3-methyl-2-oxobutanoate dehydrogenase E1-alpha chain; COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit.


ensembl_gene_id: SBI_05431
symbol: SBI_05431
gene_biotype: protein_coding
description:
  COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit.


ensembl_gene_id: SBI_05432
symbol: SBI_05432
gene_biotype: protein_coding
description:
  Branched-chain alpha-keto acid dehydrogenase subunit E2; COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes.


ensembl_gene_id: SBI_05433
symbol: SBI_05433
gene_biotype: protein_coding
description:
  Putative molybdopterin-guanine dinucleotide biosynthesis protein; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family.


ensembl_gene_id: SBI_05434
symbol: SBI_05434
gene_biotype: protein_coding
description:
  Molybdenum cofactor biosynthesis protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.


ensembl_gene_id: SBI_05443
symbol: SBI_05443
gene_biotype: protein_coding
description:
  COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit.


ensembl_gene_id: SBI_05449
symbol: SBI_05449
gene_biotype: protein_coding
description:
  Putative secreted protein; COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains).


ensembl_gene_id: SBI_05464
symbol: SBI_05464
gene_biotype: protein_coding
description:
  Putative AfsR-like transcriptional regulator; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: SBI_05477
symbol: aspS
gene_biotype: protein_coding
description:
  aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.


ensembl_gene_id: SBI_05482
symbol: metG
gene_biotype: protein_coding
description:
  methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.


ensembl_gene_id: SBI_05488
symbol: ligB
gene_biotype: protein_coding
description:
  ATP-dependent DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.


ensembl_gene_id: SBI_05491
symbol: SBI_05491
gene_biotype: protein_coding
description:
  Magnesium or manganese-dependent protein phosphatase; COG3290 Signal transduction histidine kinase regulating citrate/malate metabolism.


ensembl_gene_id: SBI_05524
symbol: SBI_05524
gene_biotype: protein_coding
description:
  Putative endonuclease/exonuclease/phosphatase family protein; COG2374 Predicted extracellular nuclease.


ensembl_gene_id: SBI_05544
symbol: SBI_05544
gene_biotype: protein_coding
description:
  methylated-DNA/protein- cysteinemethyltransferase; COG0350 Methylated DNA-protein cysteine methyltransferase.


ensembl_gene_id: SBI_05565
symbol: SBI_05565
gene_biotype: protein_coding
description:
  ABC transporter related protein; COG0577 ABC-type antimicrobial peptide transport system, permease component.


ensembl_gene_id: SBI_05592
symbol: terD2
gene_biotype: protein_coding
description:
  Tellurium resistance protein; COG2310 Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1.


ensembl_gene_id: SBI_05602
symbol: SBI_05602
gene_biotype: protein_coding
description:
  Putative MFS family transmembrane transporter; COG0477 Permeases of the major facilitator superfamily.


ensembl_gene_id: SBI_05610
symbol: SBI_05610
gene_biotype: protein_coding
description:
  Transcriptional regulator, SARP family protein; COG3947 Response regulator containing CheY-like receiver and SARP domains.


ensembl_gene_id: SBI_05633
symbol: SBI_05633
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0449 Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains.


ensembl_gene_id: SBI_05642
symbol: dcd
gene_biotype: protein_coding
description:
  Deoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.


ensembl_gene_id: SBI_05649
symbol: grpE-2
gene_biotype: protein_coding
description:
  Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...]


ensembl_gene_id: SBI_05650
symbol: dnaJ
gene_biotype: protein_coding
description:
  Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]


ensembl_gene_id: SBI_05660
symbol: sig32
gene_biotype: protein_coding
description:
  RNA polymerase, sigma-24 subunit, ECF subfamily protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family.


ensembl_gene_id: SBI_05661
symbol: sig33
gene_biotype: protein_coding
description:
  Putative RNA polymerase sigma-24 subunit, ECF subfamily protein; COG4941 Predicted RNA polymerase sigma factor containing a TPR repeat domain; Belongs to the sigma-70 factor family.


ensembl_gene_id: SBI_05666
symbol: clpB-2
gene_biotype: protein_coding
description:
  Putative ATP-dependent protease subunit; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.


ensembl_gene_id: SBI_05671
symbol: speE
gene_biotype: protein_coding
description:
  Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.


ensembl_gene_id: SBI_05674
symbol: pyrE
gene_biotype: protein_coding
description:
  Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).


ensembl_gene_id: SBI_05675
symbol: fbaA
gene_biotype: protein_coding
description:
  Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.


ensembl_gene_id: SBI_05678
symbol: tdo
gene_biotype: protein_coding
description:
  Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.


ensembl_gene_id: SBI_05685
symbol: SBI_05685
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes.


ensembl_gene_id: SBI_05686
symbol: purA
gene_biotype: protein_coding
description:
  Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.


ensembl_gene_id: SBI_05700
symbol: SBI_05700
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0188 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit.


ensembl_gene_id: SBI_05716
symbol: purC
gene_biotype: protein_coding
description:
  COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family.


ensembl_gene_id: SBI_05724
symbol: purS
gene_biotype: protein_coding
description:
  Phosphoribosylformylglycinamidine synthase subunit PurS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought  [...]


ensembl_gene_id: SBI_05725
symbol: purQ
gene_biotype: protein_coding
description:
  Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...]


ensembl_gene_id: SBI_05726
symbol: purL
gene_biotype: protein_coding
description:
  Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist  [...]


ensembl_gene_id: SBI_05729
symbol: purF
gene_biotype: protein_coding
description:
  Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.


ensembl_gene_id: SBI_05756
symbol: SBI_05756
gene_biotype: protein_coding
description:
  Putative phosphatase; COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family.


ensembl_gene_id: SBI_05758
symbol: SBI_05758
gene_biotype: protein_coding
description:
  Glyoxalase/bleomycin resistance protein/dioxygenase; COG3324 Predicted enzyme related to lactoylglutathione lyase.


ensembl_gene_id: SBI_05774
symbol: trmB
gene_biotype: protein_coding
description:
  tRNA-guanine-N7-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.


ensembl_gene_id: SBI_05821
symbol: SBI_05821
gene_biotype: protein_coding
description:
  Transcriptional regulator; COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases.


ensembl_gene_id: SBI_05822
symbol: nth
gene_biotype: protein_coding
description:
  Putative endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.


ensembl_gene_id: SBI_05827
symbol: nhaA-2
gene_biotype: protein_coding
description:
  Putative sodium/proton antiporter; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.


ensembl_gene_id: SBI_05828
symbol: acsA
gene_biotype: protein_coding
description:
  acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.


ensembl_gene_id: SBI_05841
symbol: pra2
gene_biotype: protein_coding
description:
  Replication activator protein Pra; COG0085 DNA-directed RNA polymerase, beta subunit/140 kD subunit.


ensembl_gene_id: SBI_05853
symbol: SBI_05853
gene_biotype: protein_coding
description:
  Putative ATP-dependent RNA helicase; COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster.


ensembl_gene_id: SBI_05856
symbol: hppA
gene_biotype: protein_coding
description:
  Membrane-bound proton-translocating pyrophosphatase; Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.


ensembl_gene_id: SBI_05858
symbol: SBI_05858
gene_biotype: protein_coding
description:
  rRNA or tRNA methyltransferase; COG2890 Methylase of polypeptide chain release factors; Belongs to the methyltransferase superfamily.


ensembl_gene_id: SBI_05860
symbol: topA
gene_biotype: protein_coding
description:
  Putative DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing [...]


ensembl_gene_id: SBI_05861
symbol: tmk
gene_biotype: protein_coding
description:
  Putative thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.


ensembl_gene_id: SBI_05870
symbol: hmuV
gene_biotype: protein_coding
description:
  Hemin importer ATP-binding subunit; Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system.


ensembl_gene_id: SBI_05877
symbol: SBI_05877
gene_biotype: protein_coding
description:
  Two component LuxR family transcriptional regulator; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: SBI_05880
symbol: SBI_05880
gene_biotype: protein_coding
description:
  Putative histidine protein kinase; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: SBI_05888
symbol: SBI_05888
gene_biotype: protein_coding
description:
  Endoglucanase; COG5297 Cellobiohydrolase A (1,4-beta-cellobiosidase A); Belongs to the glycosyl hydrolase family 6.


ensembl_gene_id: SBI_05889
symbol: SBI_05889
gene_biotype: protein_coding
description:
  Glycoside hydrolase family protein; COG2730 Endoglucanase; Belongs to the glycosyl hydrolase 5 (cellulase A) family.


ensembl_gene_id: SBI_05890
symbol: lspA-2
gene_biotype: protein_coding
description:
  Hypothetical protein; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.


ensembl_gene_id: SBI_05892
symbol: SBI_05892
gene_biotype: protein_coding
description:
  Hypothetical protein; COG5662 Predicted transmembrane transcriptional regulator (anti-sigma factor).


ensembl_gene_id: SBI_05895
symbol: SBI_05895
gene_biotype: protein_coding
description:
  alpha-L-arabinfuranosidase, putative, abf43M; COG3940 Predicted beta-xylosidase; Belongs to the glycosyl hydrolase 43 family.


ensembl_gene_id: SBI_05911
symbol: SBI_05911
gene_biotype: protein_coding
description:
  COG0076 Glutamate decarboxylase and related PLP-dependent proteins; Belongs to the group II decarboxylase family.


ensembl_gene_id: SBI_05916
symbol: ppa
gene_biotype: protein_coding
description:
  Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.


ensembl_gene_id: SBI_05919
symbol: tilS
gene_biotype: protein_coding
description:
  tRNA(Ile)-lysidine synthase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.


ensembl_gene_id: SBI_05920
symbol: hprT
gene_biotype: protein_coding
description:
  COG0634 Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.


ensembl_gene_id: SBI_05921
symbol: ftsH
gene_biotype: protein_coding
description:
  Cell division protein ftsH-like protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family.  In the central section; belongs to the AAA ATPase family.


ensembl_gene_id: SBI_05924
symbol: folK
gene_biotype: protein_coding
description:
  2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase.


ensembl_gene_id: SBI_05925
symbol: folX
gene_biotype: protein_coding
description:
  Putative dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.


ensembl_gene_id: SBI_05930
symbol: SBI_05930
gene_biotype: protein_coding
description:
  Putative ABC transporter ATP-binding protein; COG1125 ABC-type proline/glycine betaine transport systems, ATPase components.


ensembl_gene_id: SBI_05931
symbol: SBI_05931
gene_biotype: protein_coding
description:
  Putative ABC transporter permease protein; COG1174 ABC-type proline/glycine betaine transport systems, permease component.


ensembl_gene_id: SBI_05933
symbol: SBI_05933
gene_biotype: protein_coding
description:
  Putative ABC transporter substrate-binding protein; COG1732 Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein).


ensembl_gene_id: SBI_05935
symbol: nuoD-2
gene_biotype: protein_coding
description:
  NADH dehydrogenase I chain D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family.


ensembl_gene_id: SBI_05938
symbol: SBI_05938
gene_biotype: protein_coding
description:
  Putative two component system response regulator; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: SBI_05943
symbol: panC
gene_biotype: protein_coding
description:
  Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.


ensembl_gene_id: SBI_05946
symbol: coaX
gene_biotype: protein_coding
description:
  Pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.


ensembl_gene_id: SBI_05955
symbol: SBI_05955
gene_biotype: protein_coding
description:
  Putative ATP-dependent Clp protease; COG0542 ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family.


ensembl_gene_id: SBI_05957
symbol: SBI_05957
gene_biotype: protein_coding
description:
  COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; Belongs to the arginase family.


ensembl_gene_id: SBI_05977
symbol: SBI_05977
gene_biotype: protein_coding
description:
  SigE-like sigma factor; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: SBI_05981
symbol: disA
gene_biotype: protein_coding
description:
  DNA integrity scanning protein DisA; Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis.


ensembl_gene_id: SBI_05982
symbol: radA
gene_biotype: protein_coding
description:
  DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.


ensembl_gene_id: SBI_05993
symbol: SBI_05993
gene_biotype: protein_coding
description:
  Transmembrane transport protein; COG0659 Sulfate permease and related transporters (MFS superfamily).


ensembl_gene_id: SBI_05995
symbol: proC
gene_biotype: protein_coding
description:
  Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.


ensembl_gene_id: SBI_05999
symbol: SBI_05999
gene_biotype: protein_coding
description:
  Putative acetoin utilization protein; COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein.


ensembl_gene_id: SBI_06006
symbol: SBI_06006
gene_biotype: protein_coding
description:
  AdsA-like sigma factor; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: SBI_06009
symbol: rex
gene_biotype: protein_coding
description:
  Redox-sensing transcriptional repressor Rex; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.


ensembl_gene_id: SBI_06010
symbol: hemA
gene_biotype: protein_coding
description:
  glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).


ensembl_gene_id: SBI_06012
symbol: hemD
gene_biotype: protein_coding
description:
  Putative uroporphyrin-III C-methyltransferase/uroporphyrinogen-III synthase; COG0007 Uroporphyrinogen-III methylase.


ensembl_gene_id: SBI_06014
symbol: SBI_06014
gene_biotype: protein_coding
description:
  2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.


ensembl_gene_id: SBI_06045
symbol: SBI_06045
gene_biotype: protein_coding
description:
  ABC transporter, ATP-binding protein; COG1131 ABC-type multidrug transport system, ATPase component.


ensembl_gene_id: SBI_06050
symbol: SBI_06050
gene_biotype: protein_coding
description:
  Carboxypeptidase G2; COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases.


ensembl_gene_id: SBI_06068
symbol: SBI_06068
gene_biotype: protein_coding
description:
  Putative cytochrome assembly protein; COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component.


ensembl_gene_id: SBI_06072
symbol: ubiX
gene_biotype: protein_coding
description:
  Decarboxylase; COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases; Belongs to the UbiD family.


ensembl_gene_id: SBI_06073
symbol: ubiA
gene_biotype: protein_coding
description:
  Prenyltransferase; COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases; Belongs to the UbiA prenyltransferase family.


ensembl_gene_id: SBI_06076
symbol: mqnE
gene_biotype: protein_coding
description:
  Radical SAM domain-containing protein; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.


ensembl_gene_id: SBI_06078
symbol: SBI_06078
gene_biotype: protein_coding
description:
  Putative proton transport protein; COG1301 Na+/H+-dicarboxylate symporters; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: SBI_06082
symbol: SBI_06082
gene_biotype: protein_coding
description:
  Putative cytochrome c oxidase subunit I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.


ensembl_gene_id: SBI_06090
symbol: mqnA
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).


ensembl_gene_id: SBI_06092
symbol: mqnC
gene_biotype: protein_coding
description:
  Hypothetical protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).


ensembl_gene_id: SBI_06094
symbol: ubiE
gene_biotype: protein_coding
description:
  Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).


ensembl_gene_id: SBI_06100
symbol: nuoA
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit A; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family.


ensembl_gene_id: SBI_06101
symbol: nuoB
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit B; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: SBI_06102
symbol: nuoC
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit C; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 30 kDa subunit family.


ensembl_gene_id: SBI_06103
symbol: nuoD
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family.


ensembl_gene_id: SBI_06105
symbol: nuoF-2
gene_biotype: protein_coding
description:
  NADH dehydrogenase I chain F; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family.


ensembl_gene_id: SBI_06106
symbol: nuoG
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family.


ensembl_gene_id: SBI_06107
symbol: nuoH
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit H; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.


ensembl_gene_id: SBI_06108
symbol: nuoI
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: SBI_06109
symbol: nuoJ
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit J; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: SBI_06110
symbol: nuoK
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit K; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family.


ensembl_gene_id: SBI_06111
symbol: nuoL
gene_biotype: protein_coding
description:
  COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit.


ensembl_gene_id: SBI_06113
symbol: nuoN
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family.


ensembl_gene_id: SBI_06115
symbol: SBI_06115
gene_biotype: protein_coding
description:
  Fumarylacetoacetase; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).


ensembl_gene_id: SBI_06121
symbol: SBI_06121
gene_biotype: protein_coding
description:
  Putative ABC transporter integral membrane protein; COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component.


ensembl_gene_id: SBI_06126
symbol: SBI_06126
gene_biotype: protein_coding
description:
  COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit.


ensembl_gene_id: SBI_06127
symbol: SBI_06127
gene_biotype: protein_coding
description:
  Putative ferrodoxin oxidoreductase alpha subunit; COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit.


ensembl_gene_id: SBI_06131
symbol: nuoA2
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit NuoA2; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family.


ensembl_gene_id: SBI_06132
symbol: nuoB2
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit NuoB2; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: SBI_06134
symbol: nuoH2
gene_biotype: protein_coding
description:
  NADH dehydrogenase I chain H; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.


ensembl_gene_id: SBI_06135
symbol: nuoI2
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit NuoI2; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: SBI_06136
symbol: nuoJ2
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit NuoJ2; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: SBI_06137
symbol: nuoK2
gene_biotype: protein_coding
description:
  Putative NADH dehydrogenase chain K; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family.


ensembl_gene_id: SBI_06140
symbol: nuoN2
gene_biotype: protein_coding
description:
  NADH dehydrogenase I chain N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family.


ensembl_gene_id: SBI_06143
symbol: SBI_06143
gene_biotype: protein_coding
description:
  Putative nucleotide-binding protein; COG1666 Uncharacterized protein conserved in bacteria; Belongs to the UPF0234 family.


ensembl_gene_id: SBI_06158
symbol: secE
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.


ensembl_gene_id: SBI_06159
symbol: nusG
gene_biotype: protein_coding
description:
  Transcription antitermination protein nusG; Participates in transcription elongation, termination and antitermination.


ensembl_gene_id: SBI_06160
symbol: rplK
gene_biotype: protein_coding
description:
  50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.


ensembl_gene_id: SBI_06161
symbol: rplA
gene_biotype: protein_coding
description:
  50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.


ensembl_gene_id: SBI_06163
symbol: rplJ
gene_biotype: protein_coding
description:
  50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.


ensembl_gene_id: SBI_06164
symbol: rplL
gene_biotype: protein_coding
description:
  50S ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family.


ensembl_gene_id: SBI_06165
symbol: rpoB
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: SBI_06167
symbol: rpsL
gene_biotype: protein_coding
description:
  30S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.


ensembl_gene_id: SBI_06168
symbol: rpsG
gene_biotype: protein_coding
description:
  30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.


ensembl_gene_id: SBI_06169
symbol: fusA2
gene_biotype: protein_coding
description:
  Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.


ensembl_gene_id: SBI_06170
symbol: tuf
gene_biotype: protein_coding
description:
  Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.


ensembl_gene_id: SBI_06181
symbol: azoR-2
gene_biotype: protein_coding
description:
  Hydrolase; Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity; Belongs to the azoreductase type 1 family.


ensembl_gene_id: SBI_06183
symbol: SBI_06183
gene_biotype: protein_coding
description:
  6-phosphogluconate dehydrogenase NAD-binding protein; COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases.


ensembl_gene_id: SBI_06188
symbol: rpsJ
gene_biotype: protein_coding
description:
  30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.


ensembl_gene_id: SBI_06189
symbol: rplC
gene_biotype: protein_coding
description:
  50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.


ensembl_gene_id: SBI_06191
symbol: rplW
gene_biotype: protein_coding
description:
  Putative 50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.


ensembl_gene_id: SBI_06192
symbol: rplB
gene_biotype: protein_coding
description:
  50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.


ensembl_gene_id: SBI_06193
symbol: rpsS
gene_biotype: protein_coding
description:
  30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.


ensembl_gene_id: SBI_06194
symbol: rplV
gene_biotype: protein_coding
description:
  50S ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.


ensembl_gene_id: SBI_06195
symbol: rpsC
gene_biotype: protein_coding
description:
  30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.


ensembl_gene_id: SBI_06196
symbol: rplP
gene_biotype: protein_coding
description:
  50S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.


ensembl_gene_id: SBI_06198
symbol: rpsQ
gene_biotype: protein_coding
description:
  30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.


ensembl_gene_id: SBI_06199
symbol: rplN
gene_biotype: protein_coding
description:
  50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.


ensembl_gene_id: SBI_06200
symbol: rplX
gene_biotype: protein_coding
description:
  50S ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.


ensembl_gene_id: SBI_06201
symbol: rplE
gene_biotype: protein_coding
description:
  50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.


ensembl_gene_id: SBI_06202
symbol: rpsN-2
gene_biotype: protein_coding
description:
  30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.


ensembl_gene_id: SBI_06203
symbol: rpsH
gene_biotype: protein_coding
description:
  30S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.


ensembl_gene_id: SBI_06204
symbol: rplF
gene_biotype: protein_coding
description:
  50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.


ensembl_gene_id: SBI_06205
symbol: rplR
gene_biotype: protein_coding
description:
  50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.


ensembl_gene_id: SBI_06206
symbol: rpsE
gene_biotype: protein_coding
description:
  30S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.


ensembl_gene_id: SBI_06208
symbol: rplO
gene_biotype: protein_coding
description:
  50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.


ensembl_gene_id: SBI_06209
symbol: secY
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.


ensembl_gene_id: SBI_06210
symbol: adk
gene_biotype: protein_coding
description:
  Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.


ensembl_gene_id: SBI_06211
symbol: map1
gene_biotype: protein_coding
description:
  Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.


ensembl_gene_id: SBI_06212
symbol: infA
gene_biotype: protein_coding
description:
  Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.


ensembl_gene_id: SBI_06214
symbol: rpsM
gene_biotype: protein_coding
description:
  30S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family.


ensembl_gene_id: SBI_06215
symbol: rpsK
gene_biotype: protein_coding
description:
  30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.


ensembl_gene_id: SBI_06217
symbol: rpoA
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: SBI_06219
symbol: truA
gene_biotype: protein_coding
description:
  tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.


ensembl_gene_id: SBI_06225
symbol: rplM
gene_biotype: protein_coding
description:
  50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.


ensembl_gene_id: SBI_06227
symbol: glmM
gene_biotype: protein_coding
description:
  Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.


ensembl_gene_id: SBI_06231
symbol: glmS
gene_biotype: protein_coding
description:
  Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.


ensembl_gene_id: SBI_06243
symbol: nnrE
gene_biotype: protein_coding
description:
  Hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.  Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epi [...]


ensembl_gene_id: SBI_06244
symbol: SBI_06244
gene_biotype: protein_coding
description:
  Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.


ensembl_gene_id: SBI_06249
symbol: SBI_06249
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone.


ensembl_gene_id: SBI_06251
symbol: tsaD
gene_biotype: protein_coding
description:
  Putative DNA-binding/iron metalloprotein/AP endonuclease; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.


ensembl_gene_id: SBI_06262
symbol: groES
gene_biotype: protein_coding
description:
  Co-chaperonin GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.


ensembl_gene_id: SBI_06264
symbol: SBI_06264
gene_biotype: protein_coding
description:
  COG0300 Short-chain dehydrogenases of various substrate specificities; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: SBI_06267
symbol: whiB-4
gene_biotype: protein_coding
description:
  Putative WhiB family regulator; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.


ensembl_gene_id: SBI_06268
symbol: SBI_06268
gene_biotype: protein_coding
description:
  Putative luxR family regulator; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: SBI_06270
symbol: guaB
gene_biotype: protein_coding
description:
  IMP dehydrogenase/ GMP reductase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.


ensembl_gene_id: SBI_06275
symbol: SBI_06275
gene_biotype: protein_coding
description:
  Putative UDP-glucose/GDP-mannose dehydrogenase; COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.


ensembl_gene_id: SBI_06276
symbol: SBI_06276
gene_biotype: protein_coding
description:
  COG0578 Glycerol-3-phosphate dehydrogenase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.


ensembl_gene_id: SBI_06291
symbol: SBI_06291
gene_biotype: protein_coding
description:
  Putative oxidoreductase; COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family.


ensembl_gene_id: SBI_06317
symbol: SBI_06317
gene_biotype: protein_coding
description:
  Abhydrolase, alpha/beta hydrolase fold protein; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: SBI_06318
symbol: SBI_06318
gene_biotype: protein_coding
description:
  Putative polyketide oxygenase/hydroxylase; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.


ensembl_gene_id: SBI_06341
symbol: SBI_06341
gene_biotype: protein_coding
description:
  Putative sodium-coupled permease; COG0591 Na+/proline symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: SBI_06343
symbol: SBI_06343
gene_biotype: protein_coding
description:
  Aminotransferase; COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs.


ensembl_gene_id: SBI_06359
symbol: ku
gene_biotype: protein_coding
description:
  Hypothetical protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.


ensembl_gene_id: SBI_06379
symbol: SBI_06379
gene_biotype: protein_coding
description:
  Putative AraC family transcriptional regulator; COG2207 AraC-type DNA-binding domain-containing proteins.


ensembl_gene_id: SBI_06391
symbol: SBI_06391
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0037 Predicted ATPase of the PP-loop superfamily implicated in cell cycle control.


ensembl_gene_id: SBI_06401
symbol: vapC-2
gene_biotype: protein_coding
description:
  PilT-like protein; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family.


ensembl_gene_id: SBI_06410
symbol: SBI_06410
gene_biotype: protein_coding
description:
  Putative helix-turn-helix AraC-type trancriptional regulator; COG2207 AraC-type DNA-binding domain-containing proteins.


ensembl_gene_id: SBI_06420
symbol: SBI_06420
gene_biotype: protein_coding
description:
  Oxidoreductase; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.


ensembl_gene_id: SBI_06427
symbol: SBI_06427
gene_biotype: protein_coding
description:
  Putative integral membrane transport protein; COG1175 ABC-type sugar transport systems, permease components.


ensembl_gene_id: SBI_06428
symbol: SBI_06428
gene_biotype: protein_coding
description:
  Putative substrate-binding transport lipoprotein; COG1653 ABC-type sugar transport system, periplasmic component.


ensembl_gene_id: SBI_06432
symbol: SBI_06432
gene_biotype: protein_coding
description:
  Putative transcriptional regulator, GntR family protein; COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs.


ensembl_gene_id: SBI_06435
symbol: SBI_06435
gene_biotype: protein_coding
description:
  phytanoyl-CoA dioxygenase; COG5285 Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin.


ensembl_gene_id: SBI_06444
symbol: SBI_06444
gene_biotype: protein_coding
description:
  Non-ribosomal peptide synthase; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: SBI_06451
symbol: sig38
gene_biotype: protein_coding
description:
  RNA polymerase, sigma-24 subunit, ECF subfamily protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: SBI_06459
symbol: SBI_06459
gene_biotype: protein_coding
description:
  Iron-sulfur oxidoreductase subunit beta; COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1.


ensembl_gene_id: SBI_06460
symbol: SBI_06460
gene_biotype: protein_coding
description:
  Oxidoreductase subunit alpha; COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit.


ensembl_gene_id: SBI_06471
symbol: SBI_06471
gene_biotype: protein_coding
description:
  RNA polymerase principal sigma factor hrdD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.


ensembl_gene_id: SBI_06474
symbol: SBI_06474
gene_biotype: protein_coding
description:
  1-phosphofructokinase; COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); Belongs to the carbohydrate kinase PfkB family.


ensembl_gene_id: SBI_06479
symbol: mscL
gene_biotype: protein_coding
description:
  Mechanosensitive channel; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.


ensembl_gene_id: SBI_06485
symbol: SBI_06485
gene_biotype: protein_coding
description:
  Ligase; COG0212 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.


ensembl_gene_id: SBI_06487
symbol: moaA
gene_biotype: protein_coding
description:
  Molybdopterin biosynthesis protein MoeA; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.


ensembl_gene_id: SBI_06488
symbol: moaC
gene_biotype: protein_coding
description:
  Molybdenum cofactor biosynthesis protein MoaC; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.


ensembl_gene_id: SBI_06490
symbol: rimJ
gene_biotype: protein_coding
description:
  Putative ribosomal-protein-alanine N-acetyltransferase; COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins.


ensembl_gene_id: SBI_06493
symbol: mtnA
gene_biotype: protein_coding
description:
  Initiation factor eIF-2B alpha subunit; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).


ensembl_gene_id: SBI_06498
symbol: hpf
gene_biotype: protein_coding
description:
  Hypothetical protein; Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.


ensembl_gene_id: SBI_06502
symbol: secA
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.


ensembl_gene_id: SBI_06522
symbol: SBI_06522
gene_biotype: protein_coding
description:
  Putative sugar ABC transporter solute-binding protein; COG1653 ABC-type sugar transport system, periplasmic component.


ensembl_gene_id: SBI_06526
symbol: prfB
gene_biotype: protein_coding
description:
  Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.


ensembl_gene_id: SBI_06529
symbol: ftsE
gene_biotype: protein_coding
description:
  Cell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division.


ensembl_gene_id: SBI_06530
symbol: ftsX
gene_biotype: protein_coding
description:
  Cell division protein; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.


ensembl_gene_id: SBI_06532
symbol: smpB
gene_biotype: protein_coding
description:
  SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]


ensembl_gene_id: SBI_06554
symbol: SBI_06554
gene_biotype: protein_coding
description:
  Bifunctional uroporphyrinogen-III synthetase/response regulator domain protein; COG1587 Uroporphyrinogen-III synthase.


ensembl_gene_id: SBI_06560
symbol: SBI_06560
gene_biotype: protein_coding
description:
  DNA-binding protein HU 1; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.


ensembl_gene_id: SBI_06561
symbol: murA
gene_biotype: protein_coding
description:
  UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.


ensembl_gene_id: SBI_06562
symbol: SBI_06562
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1678 Putative transcriptional regulator; Belongs to the UPF0301 (AlgH) family.


ensembl_gene_id: SBI_06565
symbol: SBI_06565
gene_biotype: protein_coding
description:
  Sugar transporter sugar-binding protein; COG1653 ABC-type sugar transport system, periplasmic component.


ensembl_gene_id: SBI_06569
symbol: SBI_06569
gene_biotype: protein_coding
description:
  Putative oxidoreductase; COG4630 Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A.


ensembl_gene_id: SBI_06570
symbol: SBI_06570
gene_biotype: protein_coding
description:
  Hypothetical protein; COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs.


ensembl_gene_id: SBI_06571
symbol: SBI_06571
gene_biotype: protein_coding
description:
  Dehydrogenase; COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs.


ensembl_gene_id: SBI_06576
symbol: SBI_06576
gene_biotype: protein_coding
description:
  Peptidoglycan-binding domain 1 protein; COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component.


ensembl_gene_id: SBI_06593
symbol: SBI_06593
gene_biotype: protein_coding
description:
  Potassium-tellurite ethidium and proflavin transporter; COG1275 Tellurite resistance protein and related permeases.


ensembl_gene_id: SBI_06609
symbol: SBI_06609
gene_biotype: protein_coding
description:
  COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases.


ensembl_gene_id: SBI_06641
symbol: cdo
gene_biotype: protein_coding
description:
  Cysteine dioxygenase type I; COG5553 Predicted metal-dependent enzyme of the double-stranded beta helix superfamily.


ensembl_gene_id: SBI_06675
symbol: SBI_06675
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: SBI_06678
symbol: clpS
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease adaptor protein ClpS; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family.


ensembl_gene_id: SBI_06686
symbol: ptsC
gene_biotype: protein_coding
description:
  PTS transmembrane component; COG1263 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific.


ensembl_gene_id: SBI_06688
symbol: rph
gene_biotype: protein_coding
description:
  Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.


ensembl_gene_id: SBI_06690
symbol: SBI_06690
gene_biotype: protein_coding
description:
  Putative deoxyribonucleotide triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.


ensembl_gene_id: SBI_06696
symbol: SBI_06696
gene_biotype: protein_coding
description:
  Putative 10kD chaperone subunit; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter; Belongs to the GroES chaperonin family.


ensembl_gene_id: SBI_06699
symbol: SBI_06699
gene_biotype: protein_coding
description:
  Putative integral membrane transport protein; COG3694 ABC-type uncharacterized transport system, permease component.


ensembl_gene_id: SBI_06700
symbol: SBI_06700
gene_biotype: protein_coding
description:
  Putative ABC transporter ATP-binding subunit; COG4586 ABC-type uncharacterized transport system, ATPase component.


ensembl_gene_id: SBI_06715
symbol: SBI_06715
gene_biotype: protein_coding
description:
  Putative secreted endoglucanase; COG5297 Cellobiohydrolase A (1,4-beta-cellobiosidase A); Belongs to the glycosyl hydrolase family 6.


ensembl_gene_id: SBI_06727
symbol: SBI_06727
gene_biotype: protein_coding
description:
  NMT1/THI5 like domain protein; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components.


ensembl_gene_id: SBI_06730
symbol: SBI_06730
gene_biotype: protein_coding
description:
  Zinc-containing alcohol dehydrogenase; COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases.


ensembl_gene_id: SBI_06743
symbol: SBI_06743
gene_biotype: protein_coding
description:
  Putative 3-oxoacyl-ACP synthase II; COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: SBI_06745
symbol: SBI_06745
gene_biotype: protein_coding
description:
  3-oxoacyl-ACP synthase I; COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: SBI_06751
symbol: SBI_06751
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1553 Uncharacterized conserved protein involved in intracellular sulfur reduction.


ensembl_gene_id: SBI_06757
symbol: SBI_06757
gene_biotype: protein_coding
description:
  Putative 3-hydroxyacyl-ACP dehydratase; COG0764 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases.


ensembl_gene_id: SBI_06758
symbol: SBI_06758
gene_biotype: protein_coding
description:
  3-oxoacyl-ACP reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: SBI_06771
symbol: SBI_06771
gene_biotype: protein_coding
description:
  Putative hydrolase; COG2730 Endoglucanase; Belongs to the glycosyl hydrolase 5 (cellulase A) family.


ensembl_gene_id: SBI_06790
symbol: SBI_06790
gene_biotype: protein_coding
description:
  Microsomal epoxide hydrolase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: SBI_06794
symbol: SBI_06794
gene_biotype: protein_coding
description:
  Putative 3-oxoacyl-ACP reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: SBI_06806
symbol: SBI_06806
gene_biotype: protein_coding
description:
  Daunorubicin resistance ABC transporter ATPase subunit; COG1131 ABC-type multidrug transport system, ATPase component.


ensembl_gene_id: SBI_06810
symbol: SBI_06810
gene_biotype: protein_coding
description:
  Putative integral membrane protein; COG0842 ABC-type multidrug transport system, permease component.


ensembl_gene_id: SBI_06816
symbol: SBI_06816
gene_biotype: protein_coding
description:
  Putative two-component sensor; COG3290 Signal transduction histidine kinase regulating citrate/malate metabolism.


ensembl_gene_id: SBI_06817
symbol: SBI_06817
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component.


ensembl_gene_id: SBI_06818
symbol: SBI_06818
gene_biotype: protein_coding
description:
  ABC transporter permease protein; COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component.


ensembl_gene_id: SBI_06819
symbol: SBI_06819
gene_biotype: protein_coding
description:
  ABC transporter substrate-binding protein; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components.


ensembl_gene_id: SBI_06831
symbol: SBI_06831
gene_biotype: protein_coding
description:
  Putative LuxAB-like monooxygenase; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: SBI_06832
symbol: SBI_06832
gene_biotype: protein_coding
description:
  Sensory box/GGDEF family protein; COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.


ensembl_gene_id: SBI_06836
symbol: SBI_06836
gene_biotype: protein_coding
description:
  Putative type I polyketide synthase component; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II.


ensembl_gene_id: SBI_06837
symbol: SBI_06837
gene_biotype: protein_coding
description:
  Putative 4'-phosphopantetheinyl transferase; COG2091 Phosphopantetheinyl transferase; Belongs to the P-Pant transferase superfamily.


ensembl_gene_id: SBI_06842
symbol: SBI_06842
gene_biotype: protein_coding
description:
  SARP family pathway specific regulatory protein; COG3629 DNA-binding transcriptional activator of the SARP family.


ensembl_gene_id: SBI_06847
symbol: SBI_06847
gene_biotype: protein_coding
description:
  Glycosyl transferase, NDP-D-desosamine: 3-L-mycarosyl erythronolide B; COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase.


ensembl_gene_id: SBI_06849
symbol: SBI_06849
gene_biotype: protein_coding
description:
  Ribosyldihydronicotinamide dehydrogenase; COG2249 Putative NADPH-quinone reductase (modulator of drug activity B).


ensembl_gene_id: SBI_06853
symbol: SBI_06853
gene_biotype: protein_coding
description:
  Actinorhodin polyketide synthase bifunctional cyclase/dehydratase; COG2867 Oligoketide cyclase/lipid transport protein.


ensembl_gene_id: SBI_06862
symbol: SBI_06862
gene_biotype: protein_coding
description:
  Putative AMP-binding protein; COG1020 Non-ribosomal peptide synthetase modules and related proteins.


ensembl_gene_id: SBI_06863
symbol: SBI_06863
gene_biotype: protein_coding
description:
  Putative secondary metabolite biosynthesis protein; COG0332 3-oxoacyl-[acyl-carrier-protein] synthase III.


ensembl_gene_id: SBI_06865
symbol: SBI_06865
gene_biotype: protein_coding
description:
  COG1088 dTDP-D-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.


ensembl_gene_id: SBI_06866
symbol: SBI_06866
gene_biotype: protein_coding
description:
  Oxygenase; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.


ensembl_gene_id: SBI_06871
symbol: SBI_06871
gene_biotype: protein_coding
description:
  DegT/DnrJ/EryC1/StrS aminotransferase; COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; Belongs to the DegT/DnrJ/EryC1 family.


ensembl_gene_id: SBI_06872
symbol: SBI_06872
gene_biotype: protein_coding
description:
  acetoacetyl-CoA reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: SBI_06892
symbol: SBI_06892
gene_biotype: protein_coding
description:
  Cellobiose ABC transporter permease protein; COG1175 ABC-type sugar transport systems, permease components.


ensembl_gene_id: SBI_06899
symbol: guxA2
gene_biotype: protein_coding
description:
  COG5297 Cellobiohydrolase A (1,4-beta-cellobiosidase A); Belongs to the glycosyl hydrolase family 6.


ensembl_gene_id: SBI_06900
symbol: celA1
gene_biotype: protein_coding
description:
  Endo-1,4-beta-glucanase; COG2730 Endoglucanase; Belongs to the glycosyl hydrolase 5 (cellulase A) family.


ensembl_gene_id: SBI_06910
symbol: orn
gene_biotype: protein_coding
description:
  Oligoribonuclease; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family.


ensembl_gene_id: SBI_06911
symbol: SBI_06911
gene_biotype: protein_coding
description:
  A-factor-responsive transcriptional activator; COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain.


ensembl_gene_id: SBI_06914
symbol: SBI_06914
gene_biotype: protein_coding
description:
  Glutamine-fructose-6-phosphate transaminase; COG0449 Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains.


ensembl_gene_id: SBI_06937
symbol: SBI_06937
gene_biotype: protein_coding
description:
  Pyridoxal 4-dehydrogenase; COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases).


ensembl_gene_id: SBI_06947
symbol: SBI_06947
gene_biotype: protein_coding
description:
  Secreted tripeptidyl aminopeptidase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: SBI_06951
symbol: SBI_06951
gene_biotype: protein_coding
description:
  Putative sugar hydrolase; COG1472 Beta-glucosidase-related glycosidases; Belongs to the glycosyl hydrolase 3 family.


ensembl_gene_id: SBI_06956
symbol: SBI_06956
gene_biotype: protein_coding
description:
  Methyltransferase small; COG2890 Methylase of polypeptide chain release factors; Belongs to the methyltransferase superfamily.


ensembl_gene_id: SBI_06964
symbol: SBI_06964
gene_biotype: protein_coding
description:
  Putative binding-protein-dependent transporter inner membrane subunit; COG1175 ABC-type sugar transport systems, permease components.


ensembl_gene_id: SBI_06965
symbol: SBI_06965
gene_biotype: protein_coding
description:
  Putative binding-protein-dependent transporter inner membrane subunit; COG0395 ABC-type sugar transport system, permease component.


ensembl_gene_id: SBI_06969
symbol: SBI_06969
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0187 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit.


ensembl_gene_id: SBI_06972
symbol: folD-2
gene_biotype: protein_coding
description:
  Methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.


ensembl_gene_id: SBI_06983
symbol: SBI_06983
gene_biotype: protein_coding
description:
  Putative phosphate binding ABC transporter; COG0226 ABC-type phosphate transport system, periplasmic component.


ensembl_gene_id: SBI_06987
symbol: SBI_06987
gene_biotype: protein_coding
description:
  Cytolysin B transport protein; COG2274 ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain.


ensembl_gene_id: SBI_06998
symbol: rbsK
gene_biotype: protein_coding
description:
  Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.


ensembl_gene_id: SBI_06999
symbol: rbsA-2
gene_biotype: protein_coding
description:
  D-ribose ABC transporter ATP-binding protein; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family.


ensembl_gene_id: SBI_07002
symbol: recD2
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease V; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily.


ensembl_gene_id: SBI_07013
symbol: SBI_07013
gene_biotype: protein_coding
description:
  Glucosidase; COG1486 Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases.


ensembl_gene_id: SBI_07015
symbol: iolG-2
gene_biotype: protein_coding
description:
  Inositol 2-dehydrogenase; Involved in the oxidation of myo-inositol (MI) to 2-keto-myo- inositol (2KMI or 2-inosose).


ensembl_gene_id: SBI_07018
symbol: SBI_07018
gene_biotype: protein_coding
description:
  ABC transporter membrane protein; COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components.


ensembl_gene_id: SBI_07019
symbol: SBI_07019
gene_biotype: protein_coding
description:
  Sugar ABC transporter substrate-binding protein; COG1879 ABC-type sugar transport system, periplasmic component.


ensembl_gene_id: SBI_07043
symbol: ccrB
gene_biotype: protein_coding
description:
  Camphor resistance protein CrcB; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.


ensembl_gene_id: SBI_07061
symbol: SBI_07061
gene_biotype: protein_coding
description:
  3-oxoacyl-(acyl-carrier protein) reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: SBI_07068
symbol: SBI_07068
gene_biotype: protein_coding
description:
  Putative ABC transporter solute-binding protein; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; Belongs to the bacterial solute-binding protein 3 family.


ensembl_gene_id: SBI_07071
symbol: SBI_07071
gene_biotype: protein_coding
description:
  Putative sugar hydrolase; COG1486 Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases.


ensembl_gene_id: SBI_07074
symbol: SBI_07074
gene_biotype: protein_coding
description:
  Putative extracellular sugar-binding protein; COG1653 ABC-type sugar transport system, periplasmic component.


ensembl_gene_id: SBI_07078
symbol: SBI_07078
gene_biotype: protein_coding
description:
  Small conductance mechanosensitive ion channel, MscS family; COG0668 Small-conductance mechanosensitive channel.


ensembl_gene_id: SBI_07103
symbol: tig
gene_biotype: protein_coding
description:
  Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.


ensembl_gene_id: SBI_07106
symbol: clpX
gene_biotype: protein_coding
description:
  ATP-dependent protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.


ensembl_gene_id: SBI_07112
symbol: valS
gene_biotype: protein_coding
description:
  valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.


ensembl_gene_id: SBI_07115
symbol: ndk
gene_biotype: protein_coding
description:
  Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.


ensembl_gene_id: SBI_07125
symbol: rplU
gene_biotype: protein_coding
description:
  50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.


ensembl_gene_id: SBI_07127
symbol: obgE
gene_biotype: protein_coding
description:
  GTPase ObgE; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.


ensembl_gene_id: SBI_07129
symbol: proB
gene_biotype: protein_coding
description:
  Predicted gamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.


ensembl_gene_id: SBI_07131
symbol: proA
gene_biotype: protein_coding
description:
  Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.


ensembl_gene_id: SBI_07137
symbol: nadD
gene_biotype: protein_coding
description:
  Nicotinic acid mononucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).


ensembl_gene_id: SBI_07139
symbol: rsfS
gene_biotype: protein_coding
description:
  Putative iojap; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.


ensembl_gene_id: SBI_07140
symbol: gpm3
gene_biotype: protein_coding
description:
  Phosphoglycerate mutase; COG0406 Fructose-2,6-bisphosphatase; Belongs to the phosphoglycerate mutase family.


ensembl_gene_id: SBI_07153
symbol: lepA
gene_biotype: protein_coding
description:
  GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.


ensembl_gene_id: SBI_07156
symbol: hemN
gene_biotype: protein_coding
description:
  Coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.


ensembl_gene_id: SBI_07159
symbol: hrcA
gene_biotype: protein_coding
description:
  Heat-inducible transcription repressor; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons.


ensembl_gene_id: SBI_07162
symbol: sdrD
gene_biotype: protein_coding
description:
  16S ribosomal RNA methyltransferase RsmE; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.


ensembl_gene_id: SBI_07164
symbol: SBI_07164
gene_biotype: protein_coding
description:
  Putative Hit-family protein; COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases.


ensembl_gene_id: SBI_07165
symbol: rnz
gene_biotype: protein_coding
description:
  Ribonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family.


ensembl_gene_id: SBI_07168
symbol: ybeY
gene_biotype: protein_coding
description:
  Putative metalloprotease; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.


ensembl_gene_id: SBI_07172
symbol: era
gene_biotype: protein_coding
description:
  GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.


ensembl_gene_id: SBI_07175
symbol: leuA1
gene_biotype: protein_coding
description:
  2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.


ensembl_gene_id: SBI_07180
symbol: SBI_07180
gene_biotype: protein_coding
description:
  Carboxymuconolactone decarboxylase; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.


ensembl_gene_id: SBI_07182
symbol: SBI_07182
gene_biotype: protein_coding
description:
  GCN5-related N-acetyltransferase; COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins.


ensembl_gene_id: SBI_07200
symbol: SBI_07200
gene_biotype: protein_coding
description:
  Esterase/lipase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: SBI_07220
symbol: SBI_07220
gene_biotype: protein_coding
description:
  Glucose/sorbosone dehydrogenase-like protein; COG3979 Uncharacterized protein contain chitin-binding domain type 3.


ensembl_gene_id: SBI_07223
symbol: SBI_07223
gene_biotype: protein_coding
description:
  Amidase domain-containing transcriptional regulator; COG2207 AraC-type DNA-binding domain-containing proteins.


ensembl_gene_id: SBI_07231
symbol: SBI_07231
gene_biotype: protein_coding
description:
  Di-trans,poly-cis-decaprenylcistransferase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.


ensembl_gene_id: SBI_07238
symbol: SBI_07238
gene_biotype: protein_coding
description:
  Putative metal transport ABC transporter ATP-binding protein; COG1121 ABC-type Mn/Zn transport systems, ATPase component.


ensembl_gene_id: SBI_07239
symbol: SBI_07239
gene_biotype: protein_coding
description:
  COG0803 ABC-type metal ion transport system, periplasmic component/surface adhesin; Belongs to the bacterial solute-binding protein 9 family.


ensembl_gene_id: SBI_07240
symbol: glyQS
gene_biotype: protein_coding
description:
  glycyl-tRNA synthetase; Catalyzes the attachment of glycine to tRNA(Gly). Belongs to the class-II aminoacyl-tRNA synthetase family.


ensembl_gene_id: SBI_07251
symbol: SBI_07251
gene_biotype: protein_coding
description:
  Putative dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.


ensembl_gene_id: SBI_07253
symbol: SBI_07253
gene_biotype: protein_coding
description:
  Pyruvate phosphate dikinase; COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; Belongs to the PEP-utilizing enzyme family.


ensembl_gene_id: SBI_07267
symbol: SBI_07267
gene_biotype: protein_coding
description:
  Putative 3-oxoadipate enol-lactone hydrolase/4-carboxymuconolactone decarboxylase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: SBI_07271
symbol: SBI_07271
gene_biotype: protein_coding
description:
  beta-ketoadipyl-CoA thiolase; COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.


ensembl_gene_id: SBI_07284
symbol: SBI_07284
gene_biotype: protein_coding
description:
  Putative oxidoreductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: SBI_07297
symbol: SBI_07297
gene_biotype: protein_coding
description:
  Zinc-binding alcohol dehydrogenase; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases.


ensembl_gene_id: SBI_07303
symbol: SBI_07303
gene_biotype: protein_coding
description:
  Xylan 1,4-beta-xylosidase; COG1472 Beta-glucosidase-related glycosidases; Belongs to the glycosyl hydrolase 3 family.


ensembl_gene_id: SBI_07304
symbol: SBI_07304
gene_biotype: protein_coding
description:
  Binding-protein-dependent transport protein; COG0395 ABC-type sugar transport system, permease component.


ensembl_gene_id: SBI_07305
symbol: SBI_07305
gene_biotype: protein_coding
description:
  Putative binding-protein-dependent transporter; COG1175 ABC-type sugar transport systems, permease components.


ensembl_gene_id: SBI_07306
symbol: SBI_07306
gene_biotype: protein_coding
description:
  Putative extracellular solute-binding protein; COG1653 ABC-type sugar transport system, periplasmic component.


ensembl_gene_id: SBI_07322
symbol: nirB
gene_biotype: protein_coding
description:
  Nitrite reductase (NAD(P)H) large subunit; COG1251 NAD(P)H-nitrite reductase; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.


ensembl_gene_id: SBI_07343
symbol: SBI_07343
gene_biotype: protein_coding
description:
  Putative secreted sugar-binding protein; COG1653 ABC-type sugar transport system, periplasmic component.


ensembl_gene_id: SBI_07350
symbol: SBI_07350
gene_biotype: protein_coding
description:
  Adenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.


ensembl_gene_id: SBI_07352
symbol: SBI_07352
gene_biotype: protein_coding
description:
  Putative molybdopterin oxidoreductase; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: SBI_07354
symbol: SBI_07354
gene_biotype: protein_coding
description:
  Deoxyguanosinetriphosphate triphosphohydrolase-like protein; COG0232 dGTP triphosphohydrolase; Belongs to the dGTPase family. Type 2 subfamily.


ensembl_gene_id: SBI_07357
symbol: dnaG
gene_biotype: protein_coding
description:
  DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.


ensembl_gene_id: SBI_07358
symbol: sig46
gene_biotype: protein_coding
description:
  RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.


ensembl_gene_id: SBI_07359
symbol: SBI_07359
gene_biotype: protein_coding
description:
  Putative sugar kinase; COG1070 Sugar (pentulose and hexulose) kinases; Belongs to the FGGY kinase family.


ensembl_gene_id: SBI_07361
symbol: sig47
gene_biotype: protein_coding
description:
  ECF sigma factor; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family.


ensembl_gene_id: SBI_07400
symbol: SBI_07400
gene_biotype: protein_coding
description:
  Integral membrane binding-protein-dependent transport protein; COG1175 ABC-type sugar transport systems, permease components.


ensembl_gene_id: SBI_07414
symbol: SBI_07414
gene_biotype: protein_coding
description:
  DsbA oxidoreductase; COG2761 Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis.


ensembl_gene_id: SBI_07417
symbol: SBI_07417
gene_biotype: protein_coding
description:
  6-phosphogluconate dehydrogenase, NAD-binding protein; COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases.


ensembl_gene_id: SBI_07424
symbol: SBI_07424
gene_biotype: protein_coding
description:
  Putative integral membrane protein; COG2981 Uncharacterized protein involved in cysteine biosynthesis.


ensembl_gene_id: SBI_07431
symbol: SBI_07431
gene_biotype: protein_coding
description:
  Sugar transport permease; COG4214 ABC-type xylose transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: SBI_07436
symbol: SBI_07436
gene_biotype: protein_coding
description:
  Dehydratase; COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily; Belongs to the mandelate racemase/muconate lactonizing enzyme family.


ensembl_gene_id: SBI_07451
symbol: SBI_07451
gene_biotype: protein_coding
description:
  3-oxoacyl-(acyl carrier protein) synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.


ensembl_gene_id: SBI_07452
symbol: acpP
gene_biotype: protein_coding
description:
  Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.


ensembl_gene_id: SBI_07474
symbol: aceE
gene_biotype: protein_coding
description:
  Pyruvate dehydrogenase subunit E1; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


ensembl_gene_id: SBI_07505
symbol: SBI_07505
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1787 Predicted endonuclease distantly related to archaeal Holliday junction resolvase and Mrr-like restriction enzymes.


ensembl_gene_id: SBI_07515
symbol: SBI_07515
gene_biotype: protein_coding
description:
  Putative secreted transglycosylase; COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains).


ensembl_gene_id: SBI_07536
symbol: SBI_07536
gene_biotype: protein_coding
description:
  Oxidoreductase, aldo/keto reductase family protein; COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases).


ensembl_gene_id: SBI_07537
symbol: SBI_07537
gene_biotype: protein_coding
description:
  Molybdopterin oxidoreductase; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: SBI_07545
symbol: SBI_07545
gene_biotype: protein_coding
description:
  Putative monooxygenase; COG2329 Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides.


ensembl_gene_id: SBI_07579
symbol: SBI_07579
gene_biotype: protein_coding
description:
  Acetyltransferase, GNAT family protein; COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins.


ensembl_gene_id: SBI_07580
symbol: SBI_07580
gene_biotype: protein_coding
description:
  Protein-L-isoaspartatecarboxylmethyltransferase- like protein; COG2518 Protein-L-isoaspartate carboxylmethyltransferase.


ensembl_gene_id: SBI_07596
symbol: SBI_07596
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding membrane translocator, AmfB; COG1132 ABC-type multidrug transport system, ATPase and permease components.


ensembl_gene_id: SBI_07597
symbol: SBI_07597
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein, AmfA; COG1132 ABC-type multidrug transport system, ATPase and permease components.


ensembl_gene_id: SBI_07603
symbol: SBI_07603
gene_biotype: protein_coding
description:
  FMN-dependent monooxygenase; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: SBI_07619
symbol: fabG-3
gene_biotype: protein_coding
description:
  3-ketoacyl-(acyl-carrier-protein) reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: SBI_07670
symbol: SBI_07670
gene_biotype: protein_coding
description:
  Putative transcriptional regulator, AraC family, isolated domain protein; COG2207 AraC-type DNA-binding domain-containing proteins.


ensembl_gene_id: SBI_07680
symbol: SBI_07680
gene_biotype: protein_coding
description:
  Iron-dependent peroxidase; Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the tetrapyrrol ring intact. Belongs to the DyP-type peroxidase family.


ensembl_gene_id: SBI_07697
symbol: panB
gene_biotype: protein_coding
description:
  3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.


ensembl_gene_id: SBI_07704
symbol: nadE
gene_biotype: protein_coding
description:
  NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.


ensembl_gene_id: SBI_07708
symbol: SBI_07708
gene_biotype: protein_coding
description:
  Putative acyl-CoA synthetase; COG1020 Non-ribosomal peptide synthetase modules and related proteins; Belongs to the ATP-dependent AMP-binding enzyme family.


ensembl_gene_id: SBI_07731
symbol: SBI_07731
gene_biotype: protein_coding
description:
  Putative ABC transporter maltose-binding protein; COG1653 ABC-type sugar transport system, periplasmic component.


ensembl_gene_id: SBI_07732
symbol: SBI_07732
gene_biotype: protein_coding
description:
  Putative maltose ABC transporter permease protein; COG1175 ABC-type sugar transport systems, permease components.


ensembl_gene_id: SBI_07733
symbol: SBI_07733
gene_biotype: protein_coding
description:
  Putative maltose ABC transporter permease protein; COG0395 ABC-type sugar transport system, permease component.


ensembl_gene_id: SBI_07761
symbol: SBI_07761
gene_biotype: protein_coding
description:
  Regulatory protein; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: SBI_07777
symbol: lipA
gene_biotype: protein_coding
description:
  Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.


ensembl_gene_id: SBI_07778
symbol: lipB
gene_biotype: protein_coding
description:
  Lipoyltransferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.


ensembl_gene_id: SBI_07781
symbol: SBI_07781
gene_biotype: protein_coding
description:
  Putative NAD dependent epimerase/dehydratase family protein; COG1090 Predicted nucleoside-diphosphate sugar epimerase.


ensembl_gene_id: SBI_07787
symbol: aceE1
gene_biotype: protein_coding
description:
  2-oxoacid dehydrogenase subunit E1; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


ensembl_gene_id: SBI_07789
symbol: sucB
gene_biotype: protein_coding
description:
  Putative dihydrolipoamide S-succinyltransferase; COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes.


ensembl_gene_id: SBI_07791
symbol: pepA
gene_biotype: protein_coding
description:
  Leucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.


ensembl_gene_id: SBI_07792
symbol: cobU
gene_biotype: protein_coding
description:
  Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.


ensembl_gene_id: SBI_07795
symbol: cobT
gene_biotype: protein_coding
description:
  Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).


ensembl_gene_id: SBI_07805
symbol: nadA
gene_biotype: protein_coding
description:
  Quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.


ensembl_gene_id: SBI_07809
symbol: SBI_07809
gene_biotype: protein_coding
description:
  Aminotransferase; COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes; Belongs to the sulfur carrier protein TusA family.


ensembl_gene_id: SBI_07812
symbol: SBI_07812
gene_biotype: protein_coding
description:
  Hypothetical protein; Part of cytochrome c oxidase, its function is unknown. Belongs to the cytochrome c oxidase bacterial subunit CtaF family.


ensembl_gene_id: SBI_07819
symbol: trpD
gene_biotype: protein_coding
description:
  Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).


ensembl_gene_id: SBI_07826
symbol: SBI_07826
gene_biotype: protein_coding
description:
  NPL/P60-family secreted protein; COG0791 Cell wall-associated hydrolases (invasion-associated proteins).


ensembl_gene_id: SBI_07831
symbol: SBI_07831
gene_biotype: protein_coding
description:
  acyl-CoA synthetase, long-chain fatty acid:CoA ligase; COG1022 Long-chain acyl-CoA synthetases (AMP-forming).


ensembl_gene_id: SBI_07845
symbol: aroG
gene_biotype: protein_coding
description:
  Phospho-2-dehydro-3-deoxyheptonate aldolase; COG3200 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; Belongs to the class-II DAHP synthase family.


ensembl_gene_id: SBI_07847
symbol: bfrA
gene_biotype: protein_coding
description:
  Bacterioferritin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family.


ensembl_gene_id: SBI_07850
symbol: nfo
gene_biotype: protein_coding
description:
  Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.


ensembl_gene_id: SBI_07853
symbol: thiG
gene_biotype: protein_coding
description:
  Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.


ensembl_gene_id: SBI_07858
symbol: thiE
gene_biotype: protein_coding
description:
  Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.


ensembl_gene_id: SBI_07859
symbol: SBI_07859
gene_biotype: protein_coding
description:
  COG0685 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.


ensembl_gene_id: SBI_07867
symbol: SBI_07867
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1721 Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain).


ensembl_gene_id: SBI_07870
symbol: mraW
gene_biotype: protein_coding
description:
  S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.


ensembl_gene_id: SBI_07873
symbol: SBI_07873
gene_biotype: protein_coding
description:
  Putative cell wall biosynthesis protein; COG0768 Cell division protein FtsI/penicillin-binding protein 2.


ensembl_gene_id: SBI_07874
symbol: murE
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.


ensembl_gene_id: SBI_07875
symbol: murF
gene_biotype: protein_coding
description:
  Putative UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate-D-alanyl-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.


ensembl_gene_id: SBI_07876
symbol: mraY
gene_biotype: protein_coding
description:
  phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.


ensembl_gene_id: SBI_07877
symbol: murD
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.


ensembl_gene_id: SBI_07879
symbol: murG
gene_biotype: protein_coding
description:
  Undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.


ensembl_gene_id: SBI_07880
symbol: ftsQ
gene_biotype: protein_coding
description:
  Cell division protein ftsQ; Essential cell division protein; Belongs to the FtsQ/DivIB family. FtsQ subfamily.


ensembl_gene_id: SBI_07881
symbol: ftsZ
gene_biotype: protein_coding
description:
  Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.


ensembl_gene_id: SBI_07884
symbol: sepF
gene_biotype: protein_coding
description:
  Cell division protein sepF 2; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.


ensembl_gene_id: SBI_07887
symbol: ileS
gene_biotype: protein_coding
description:
  isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.


ensembl_gene_id: SBI_07891
symbol: SBI_07891
gene_biotype: protein_coding
description:
  Putative ribosomal large subunit pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.


ensembl_gene_id: SBI_07907
symbol: hisD
gene_biotype: protein_coding
description:
  Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.


ensembl_gene_id: SBI_07908
symbol: hisC1
gene_biotype: protein_coding
description:
  COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.


ensembl_gene_id: SBI_07911
symbol: hisH
gene_biotype: protein_coding
description:
  Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.


ensembl_gene_id: SBI_07912
symbol: hisA
gene_biotype: protein_coding
description:
  Phosphoribosyl isomerase A; Involved in both the histidine and tryptophan biosynthetic pathways; Belongs to the HisA/HisF family.


ensembl_gene_id: SBI_07914
symbol: hisF
gene_biotype: protein_coding
description:
  Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.


ensembl_gene_id: SBI_07935
symbol: hisI
gene_biotype: protein_coding
description:
  phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.


ensembl_gene_id: SBI_07936
symbol: trpE
gene_biotype: protein_coding
description:
  Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...]


ensembl_gene_id: SBI_07941
symbol: trpB
gene_biotype: protein_coding
description:
  Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.


ensembl_gene_id: SBI_07942
symbol: trpA
gene_biotype: protein_coding
description:
  Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.


ensembl_gene_id: SBI_07944
symbol: lgt
gene_biotype: protein_coding
description:
  Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.


ensembl_gene_id: SBI_07961
symbol: narG3
gene_biotype: protein_coding
description:
  COG5013 Nitrate reductase alpha subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: SBI_07966
symbol: SBI_07966
gene_biotype: protein_coding
description:
  Putative amino acid decarboxylase; COG0076 Glutamate decarboxylase and related PLP-dependent proteins.


ensembl_gene_id: SBI_07975
symbol: SBI_07975
gene_biotype: protein_coding
description:
  COG4177 ABC-type branched-chain amino acid transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: SBI_07976
symbol: SBI_07976
gene_biotype: protein_coding
description:
  COG0559 Branched-chain amino acid ABC-type transport system, permease components; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: SBI_07980
symbol: SBI_07980
gene_biotype: protein_coding
description:
  COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: SBI_07981
symbol: polA
gene_biotype: protein_coding
description:
  DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.


ensembl_gene_id: SBI_07991
symbol: coaE
gene_biotype: protein_coding
description:
  dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.


ensembl_gene_id: SBI_08014
symbol: uvrB
gene_biotype: protein_coding
description:
  Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate  [...]


ensembl_gene_id: SBI_08016
symbol: SBI_08016
gene_biotype: protein_coding
description:
  Export associated protein; COG2310 Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1.


ensembl_gene_id: SBI_08021
symbol: uvrA
gene_biotype: protein_coding
description:
  Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.


ensembl_gene_id: SBI_08024
symbol: uvrC
gene_biotype: protein_coding
description:
  Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.


ensembl_gene_id: SBI_08026
symbol: SBI_08026
gene_biotype: protein_coding
description:
  Hypothetical protein; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family.


ensembl_gene_id: SBI_08027
symbol: whiA
gene_biotype: protein_coding
description:
  Putative sporulation transcription regulator whiA; Involved in cell division and chromosome segregation.


ensembl_gene_id: SBI_08031
symbol: tpiA
gene_biotype: protein_coding
description:
  Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.


ensembl_gene_id: SBI_08032
symbol: secG
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.


ensembl_gene_id: SBI_08041
symbol: ctaB
gene_biotype: protein_coding
description:
  Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.


ensembl_gene_id: SBI_08048
symbol: SBI_08048
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0719 ABC-type transport system involved in Fe-S cluster assembly, permease component.


ensembl_gene_id: SBI_08051
symbol: SBI_08051
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding subunit; COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component.


ensembl_gene_id: SBI_08052
symbol: SBI_08052
gene_biotype: protein_coding
description:
  Aminotransferase; COG0520 Selenocysteine lyase; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: SBI_08055
symbol: SBI_08055
gene_biotype: protein_coding
description:
  SMR-type multi-drug efflux transporter; COG2076 Membrane transporters of cations and cationic drugs.


ensembl_gene_id: SBI_08057
symbol: dapD
gene_biotype: protein_coding
description:
  2,3,4,5-tetrahydropyridine-2- carboxylate N-succinyltransferase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.


ensembl_gene_id: SBI_08063
symbol: SBI_08063
gene_biotype: protein_coding
description:
  Putative stress-induced protein; COG2310 Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1.


ensembl_gene_id: SBI_08082
symbol: dctA3
gene_biotype: protein_coding
description:
  COG1301 Na+/H+-dicarboxylate symporters; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: SBI_08097
symbol: SBI_08097
gene_biotype: protein_coding
description:
  Transcriptional regulator-like protein; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: SBI_08102
symbol: dapA1
gene_biotype: protein_coding
description:
  5-dehydro-4-deoxyglucarate dehydratase; COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase; Belongs to the DapA family.


ensembl_gene_id: SBI_08131
symbol: ectC
gene_biotype: protein_coding
description:
  L-ectoine synthase; Catalyzes the circularization of gamma-N-acetyl-alpha,gamma- diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4- pyrimidine carboxylic acid), which is an excellent osmoprotectant.


ensembl_gene_id: SBI_08132
symbol: ectB
gene_biotype: protein_coding
description:
  Diaminobutyrate--2-oxoglutarate aminotransferase; Catalyzes reversively the conversion of L-aspartate beta- semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: SBI_08133
symbol: ectA
gene_biotype: protein_coding
description:
  Putative L-2,4-diaminobutyrate acetyltransferase; Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A.


ensembl_gene_id: SBI_08138
symbol: SBI_08138
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase.


ensembl_gene_id: SBI_08141
symbol: cobB
gene_biotype: protein_coding
description:
  Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.


ensembl_gene_id: SBI_08144
symbol: cobQ
gene_biotype: protein_coding
description:
  Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.


ensembl_gene_id: SBI_08145
symbol: cobD
gene_biotype: protein_coding
description:
  Cobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.


ensembl_gene_id: SBI_08149
symbol: fucA
gene_biotype: protein_coding
description:
  Fuculose-1-phosphate aldolase; COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases.


ensembl_gene_id: SBI_08164
symbol: SBI_08164
gene_biotype: protein_coding
description:
  Putative ssp-like protease; COG1404 Subtilisin-like serine proteases; Belongs to the peptidase S8 family.


ensembl_gene_id: SBI_08166
symbol: SBI_08166
gene_biotype: protein_coding
description:
  Transmembrane transport protein; COG4147 Predicted symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: SBI_08167
symbol: moaA-2
gene_biotype: protein_coding
description:
  Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.


ensembl_gene_id: SBI_08171
symbol: tyrS
gene_biotype: protein_coding
description:
  tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr). Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: SBI_08217
symbol: fepD
gene_biotype: protein_coding
description:
  COG0609 ABC-type Fe3+-siderophore transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: SBI_08218
symbol: fepG
gene_biotype: protein_coding
description:
  Putative iron-siderophore uptake system transmembrane component; COG4779 ABC-type enterobactin transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: SBI_08219
symbol: fepC
gene_biotype: protein_coding
description:
  Iron-siderophore uptake system ATP-binding component; COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components.


ensembl_gene_id: SBI_08223
symbol: ppnK
gene_biotype: protein_coding
description:
  Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.


ensembl_gene_id: SBI_08231
symbol: SBI_08231
gene_biotype: protein_coding
description:
  Putative recombination and DNA repair protein; May be involved in recombinational repair of damaged DNA.


ensembl_gene_id: SBI_08236
symbol: nudF
gene_biotype: protein_coding
description:
  ADP-ribose pyrophosphatase; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes.


ensembl_gene_id: SBI_08241
symbol: SBI_08241
gene_biotype: protein_coding
description:
  Hypothetical protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.


ensembl_gene_id: SBI_08242
symbol: SBI_08242
gene_biotype: protein_coding
description:
  Transcriptional regulator; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.


ensembl_gene_id: SBI_08243
symbol: rluB
gene_biotype: protein_coding
description:
  Putative pseudouridine synthase; COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; Belongs to the pseudouridine synthase RsuA family.


ensembl_gene_id: SBI_08248
symbol: engA
gene_biotype: protein_coding
description:
  GTP-binding protein EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.


ensembl_gene_id: SBI_08255
symbol: SBI_08255
gene_biotype: protein_coding
description:
  Putative cytochrome c oxidase subunit 1-beta; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.


ensembl_gene_id: SBI_08261
symbol: sepF-2
gene_biotype: protein_coding
description:
  Hypothetical protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.


ensembl_gene_id: SBI_08264
symbol: SBI_08264
gene_biotype: protein_coding
description:
  FMNH2-utilizing oxygenase; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: SBI_08265
symbol: SBI_08265
gene_biotype: protein_coding
description:
  Putative FMNH2-utilizing oxygenase; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: SBI_08271
symbol: SBI_08271
gene_biotype: protein_coding
description:
  Beta-lactamase family protein; COG1680 Beta-lactamase class C and other penicillin binding proteins.


ensembl_gene_id: SBI_08272
symbol: SBI_08272
gene_biotype: protein_coding
description:
  Streptogrisin D precursor; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain.


ensembl_gene_id: SBI_08274
symbol: SBI_08274
gene_biotype: protein_coding
description:
  Zn-binding oxidoreductase; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases.


ensembl_gene_id: SBI_08276
symbol: dnaE3
gene_biotype: protein_coding
description:
  COG0587 DNA polymerase III, alpha subunit; Belongs to the DNA polymerase type-C family. DnaE2 subfamily.


ensembl_gene_id: SBI_08278
symbol: SBI_08278
gene_biotype: protein_coding
description:
  COG3576 Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase.


ensembl_gene_id: SBI_08279
symbol: SBI_08279
gene_biotype: protein_coding
description:
  Secreted lipase; COG1075 Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold.


ensembl_gene_id: SBI_08304
symbol: SBI_08304
gene_biotype: protein_coding
description:
  Oxidoreductase, zinc-binding dehydrogenase family protein; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases.


ensembl_gene_id: SBI_08317
symbol: SBI_08317
gene_biotype: protein_coding
description:
  Putative oxidoreductase; COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs.


ensembl_gene_id: SBI_08318
symbol: SBI_08318
gene_biotype: protein_coding
description:
  Bifunctional: xanthine dehydrogenase/ 4-hydroxybenzoyl-CoA reductase; COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs.


ensembl_gene_id: SBI_08338
symbol: SBI_08338
gene_biotype: protein_coding
description:
  Putative two-component system response regulator; COG4565 Response regulator of citrate/malate metabolism.


ensembl_gene_id: SBI_08363
symbol: hmgA
gene_biotype: protein_coding
description:
  Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.


ensembl_gene_id: SBI_08365
symbol: SBI_08365
gene_biotype: protein_coding
description:
  Dehydrogenase; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: SBI_08377
symbol: SBI_08377
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1405 Transcription initiation factor TFIIIB, Brf1 subunit/Transcription initiation factor TFIIB.


ensembl_gene_id: SBI_08381
symbol: SBI_08381
gene_biotype: protein_coding
description:
  acyl-CoA synthetase, long chain-fatty acid:CoA ligase; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II.


ensembl_gene_id: SBI_08386
symbol: SBI_08386
gene_biotype: protein_coding
description:
  Putative zinc-binding oxidoreductase; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases.


ensembl_gene_id: SBI_08409
symbol: nanG2
gene_biotype: protein_coding
description:
  Putative dTDP-glucose 4,6-dehydratase; COG1088 dTDP-D-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.


ensembl_gene_id: SBI_08410
symbol: nanG3
gene_biotype: protein_coding
description:
  Putative NDP-D-glucose-3,4-dehydratase; COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; Belongs to the DegT/DnrJ/EryC1 family.


ensembl_gene_id: SBI_08412
symbol: nanM
gene_biotype: protein_coding
description:
  Putative methyltransferase; COG2230 Cyclopropane fatty acid synthase and related methyltransferases.


ensembl_gene_id: SBI_08421
symbol: nanR1
gene_biotype: protein_coding
description:
  Activator protein; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: SBI_08425
symbol: nanT3
gene_biotype: protein_coding
description:
  Two component transcriptional regulator, LuxR family protein; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: SBI_08434
symbol: SBI_08434
gene_biotype: protein_coding
description:
  Bicupin, oxalate decarboxylase family protein; COG2140 Thermophilic glucose-6-phosphate isomerase and related metalloenzymes.


ensembl_gene_id: SBI_08445
symbol: SBI_08445
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member.


ensembl_gene_id: SBI_08449
symbol: corA
gene_biotype: protein_coding
description:
  Putative ion transport protein; Mediates influx of magnesium ions. Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.


ensembl_gene_id: SBI_08453
symbol: cysS2
gene_biotype: protein_coding
description:
  cysteinyl-tRNA synthetase; Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins; Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.


ensembl_gene_id: SBI_08455
symbol: SBI_08455
gene_biotype: protein_coding
description:
  Putative racemase; COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily; Belongs to the mandelate racemase/muconate lactonizing enzyme family.


ensembl_gene_id: SBI_08459
symbol: SBI_08459
gene_biotype: protein_coding
description:
  Putative ABC transporter integral membrane component; COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components.


ensembl_gene_id: SBI_08465
symbol: glpK-2
gene_biotype: protein_coding
description:
  Putative glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.


ensembl_gene_id: SBI_08466
symbol: SBI_08466
gene_biotype: protein_coding
description:
  COG0580 Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family); Belongs to the MIP/aquaporin (TC 1.A.8) family.


ensembl_gene_id: SBI_08468
symbol: SBI_08468
gene_biotype: protein_coding
description:
  Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.


ensembl_gene_id: SBI_08470
symbol: SBI_08470
gene_biotype: protein_coding
description:
  Lipoprotein oligopeptide binding protein; COG0747 ABC-type dipeptide transport system, periplasmic component.


ensembl_gene_id: SBI_08475
symbol: SBI_08475
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.


ensembl_gene_id: SBI_08478
symbol: arc
gene_biotype: protein_coding
description:
  ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.


ensembl_gene_id: SBI_08480
symbol: pup
gene_biotype: protein_coding
description:
  Hypothetical protein; Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.


ensembl_gene_id: SBI_08483
symbol: prcA
gene_biotype: protein_coding
description:
  20S proteasome,subunit A and B; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1A family.


ensembl_gene_id: SBI_08486
symbol: pafA
gene_biotype: protein_coding
description:
  Proteasome component; Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side- chain amino group of a substrate lysine.


ensembl_gene_id: SBI_08493
symbol: tatA
gene_biotype: protein_coding
description:
  Hypothetical protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.


ensembl_gene_id: SBI_08494
symbol: tatC
gene_biotype: protein_coding
description:
  Putative sec-independent protein translocase protein TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.


ensembl_gene_id: SBI_08510
symbol: SBI_08510
gene_biotype: protein_coding
description:
  Transcriptional regulator, Crp/Fnr family protein; COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases.


ensembl_gene_id: SBI_08545
symbol: SBI_08545
gene_biotype: protein_coding
description:
  Transcriptional regulator, SARP family protein; COG1652 Uncharacterized protein containing LysM domain.


ensembl_gene_id: SBI_08568
symbol: SBI_08568
gene_biotype: protein_coding
description:
  Putative RNA methylase; COG0863 DNA modification methylase; Belongs to the N(4)/N(6)-methyltransferase family.


ensembl_gene_id: SBI_08580
symbol: SBI_08580
gene_biotype: protein_coding
description:
  Glycoside hydrolase family 43; COG3507 Beta-xylosidase; Belongs to the glycosyl hydrolase 43 family.


ensembl_gene_id: SBI_08582
symbol: SBI_08582
gene_biotype: protein_coding
description:
  Putative glycosyl hydrolase/xylanase; COG3507 Beta-xylosidase; Belongs to the glycosyl hydrolase 43 family.


ensembl_gene_id: SBI_08599
symbol: SBI_08599
gene_biotype: protein_coding
description:
  Fumarylacetoacetate (FAA) hydrolase; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).


ensembl_gene_id: SBI_08600
symbol: SBI_08600
gene_biotype: protein_coding
description:
  Putative short-chain dehydrogenase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: SBI_08607
symbol: SBI_08607
gene_biotype: protein_coding
description:
  Putative short-chain dehydrogenase/oxidoreductase; COG4221 Short-chain alcohol dehydrogenase of unknown specificity; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: SBI_08611
symbol: SBI_08611
gene_biotype: protein_coding
description:
  NAD dependent epimerase/dehydratase family protein; COG0702 Predicted nucleoside-diphosphate-sugar epimerases.


ensembl_gene_id: SBI_08630
symbol: SBI_08630
gene_biotype: protein_coding
description:
  Binding-protein-dependent transport systems inner membrane component; COG4209 ABC-type polysaccharide transport system, permease component.


ensembl_gene_id: SBI_08651
symbol: echA13
gene_biotype: protein_coding
description:
  Putative enoyl-CoA hydratase/isomerase family protein; COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: SBI_08655
symbol: SBI_08655
gene_biotype: protein_coding
description:
  Luciferase family protein; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: SBI_08658
symbol: SBI_08658
gene_biotype: protein_coding
description:
  3-oxoacyl-(acyl-carrier-protein) reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: SBI_08672
symbol: maiA
gene_biotype: protein_coding
description:
  Maleate cis-trans isomerase; Catalyzes cis-trans isomerization of the C2-C3 double bond in maleate to yield fumarate.


ensembl_gene_id: SBI_08686
symbol: SBI_08686
gene_biotype: protein_coding
description:
  Putative carboxyesterase; COG2272 Carboxylesterase type B; Belongs to the type-B carboxylesterase/lipase family.


ensembl_gene_id: SBI_08688
symbol: SBI_08688
gene_biotype: protein_coding
description:
  Putative dioxygenase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: SBI_08723
symbol: SBI_08723
gene_biotype: protein_coding
description:
  Transposase IS204/IS1001/IS1096/IS1165 family protein; COG3464 Transposase and inactivated derivatives.


ensembl_gene_id: SBI_08732
symbol: SBI_08732
gene_biotype: protein_coding
description:
  CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; COG0558 Phosphatidylglycerophosphate synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: SBI_08733
symbol: SBI_08733
gene_biotype: protein_coding
description:
  Mannose-1-phosphate guanyltransferase; COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon).


ensembl_gene_id: SBI_08735
symbol: SBI_08735
gene_biotype: protein_coding
description:
  Putative integral membrane protein; COG3856 Uncharacterized conserved protein (small basic protein).


ensembl_gene_id: SBI_08741
symbol: dinB
gene_biotype: protein_coding
description:
  DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.


ensembl_gene_id: SBI_08743
symbol: gcvP
gene_biotype: protein_coding
description:
  Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.


ensembl_gene_id: SBI_08761
symbol: SBI_08761
gene_biotype: protein_coding
description:
  Putative pyridoxamine 5'-phosphate oxidase-related protein; COG0748 Putative heme iron utilization protein.


ensembl_gene_id: SBI_08777
symbol: SBI_08777
gene_biotype: protein_coding
description:
  Sugar ABC transporter, ATP-binding protein; COG1129 ABC-type sugar transport system, ATPase component.


ensembl_gene_id: SBI_08784
symbol: SBI_08784
gene_biotype: protein_coding
description:
  Putative transcriptional regulator; COG3284 Transcriptional activator of acetoin/glycerol metabolism.


ensembl_gene_id: SBI_08786
symbol: SBI_08786
gene_biotype: protein_coding
description:
  GntR family regulatory protein; COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs.


ensembl_gene_id: SBI_08789
symbol: SBI_08789
gene_biotype: protein_coding
description:
  Putative extracellular solute-binding protein; COG0747 ABC-type dipeptide transport system, periplasmic component.


ensembl_gene_id: SBI_08793
symbol: SBI_08793
gene_biotype: protein_coding
description:
  Oligopeptide/dipeptide ABC transporter ATPase subunit; COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component.


ensembl_gene_id: SBI_08794
symbol: SBI_08794
gene_biotype: protein_coding
description:
  Glutathione import ATP-binding protein GsiA; COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase; Belongs to the ABC transporter superfamily.


ensembl_gene_id: SBI_08796
symbol: SBI_08796
gene_biotype: protein_coding
description:
  Trimethylamine-N-oxide reductase; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: SBI_08801
symbol: SBI_08801
gene_biotype: protein_coding
description:
  Putative ABC transporter permease protein; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases.


ensembl_gene_id: SBI_08802
symbol: SBI_08802
gene_biotype: protein_coding
description:
  Putative ABC transporter ATP-binding protein; COG1126 ABC-type polar amino acid transport system, ATPase component.


ensembl_gene_id: SBI_08803
symbol: SBI_08803
gene_biotype: protein_coding
description:
  Putative ABC transporter substrate-binding protein; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain.


ensembl_gene_id: SBI_08807
symbol: uppP
gene_biotype: protein_coding
description:
  Undecaprenyl pyrophosphate phosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.


ensembl_gene_id: SBI_08826
symbol: sbcD
gene_biotype: protein_coding
description:
  Putative exonuclease; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.


ensembl_gene_id: SBI_08833
symbol: SBI_08833
gene_biotype: protein_coding
description:
  Putative integral membrane protein; COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily.


ensembl_gene_id: SBI_08835
symbol: sig54
gene_biotype: protein_coding
description:
  ECF-sigma factor; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family.


ensembl_gene_id: SBI_08860
symbol: SBI_08860
gene_biotype: protein_coding
description:
  Glycosyl hydrolase; COG1472 Beta-glucosidase-related glycosidases; Belongs to the glycosyl hydrolase 3 family.


ensembl_gene_id: SBI_08861
symbol: bioD
gene_biotype: protein_coding
description:
  Dithiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.


ensembl_gene_id: SBI_08862
symbol: bioA
gene_biotype: protein_coding
description:
  Adenosylmethionine--8-amino-7-oxononanoate transaminase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.


ensembl_gene_id: SBI_08863
symbol: bioB
gene_biotype: protein_coding
description:
  Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.


ensembl_gene_id: SBI_08870
symbol: SBI_08870
gene_biotype: protein_coding
description:
  Secreted NLP/P60 family protein; COG0791 Cell wall-associated hydrolases (invasion-associated proteins).


ensembl_gene_id: SBI_08872
symbol: clpP-3
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease, protease subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.


ensembl_gene_id: SBI_08874
symbol: ureA
gene_biotype: protein_coding
description:
  Urease subunit gamma; COG0831 Urea amidohydrolase (urease) gamma subunit; Belongs to the urease gamma subunit family.


ensembl_gene_id: SBI_08875
symbol: ureB
gene_biotype: protein_coding
description:
  Urease subunit beta; COG0832 Urea amidohydrolase (urease) beta subunit; Belongs to the urease beta subunit family.


ensembl_gene_id: SBI_08877
symbol: ureF
gene_biotype: protein_coding
description:
  Urease accessroy protein; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.


ensembl_gene_id: SBI_08878
symbol: ureG
gene_biotype: protein_coding
description:
  Urease accessory protein; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.


ensembl_gene_id: SBI_08879
symbol: ureD
gene_biotype: protein_coding
description:
  Urease accessory protein; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.


ensembl_gene_id: SBI_08880
symbol: SBI_08880
gene_biotype: protein_coding
description:
  Secreted tripeptidylaminopeptidase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: SBI_08915
symbol: SBI_08915
gene_biotype: protein_coding
description:
  ABC transporter related protein; COG1132 ABC-type multidrug transport system, ATPase and permease components.


ensembl_gene_id: SBI_08918
symbol: SBI_08918
gene_biotype: protein_coding
description:
  4-hydroxythreonine-4-phosphate dehydrogenase; COG3395 Uncharacterized protein conserved in bacteria.


ensembl_gene_id: SBI_08922
symbol: SBI_08922
gene_biotype: protein_coding
description:
  Putative oligopeptide ABC transporter ATP-binding protein; COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase; Belongs to the ABC transporter superfamily.


ensembl_gene_id: SBI_08923
symbol: SBI_08923
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG4608 ABC-type oligopeptide transport system, ATPase component.


ensembl_gene_id: SBI_08936
symbol: SBI_08936
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: SBI_08941
symbol: SBI_08941
gene_biotype: protein_coding
description:
  phenylacetate-CoA ligase; Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).


ensembl_gene_id: SBI_08952
symbol: SBI_08952
gene_biotype: protein_coding
description:
  Oxidoreductase, molybdopterin-binding subunit; COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs.


ensembl_gene_id: SBI_08953
symbol: SBI_08953
gene_biotype: protein_coding
description:
  Putative oxidoreductase, iron-sulfur binding subunit; COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs.


ensembl_gene_id: SBI_08964
symbol: SBI_08964
gene_biotype: protein_coding
description:
  Binding protein dependent transport protein; COG1175 ABC-type sugar transport systems, permease components.


ensembl_gene_id: SBI_08965
symbol: SBI_08965
gene_biotype: protein_coding
description:
  Binding protein dependent transport protein; COG0395 ABC-type sugar transport system, permease component.


ensembl_gene_id: SBI_08976
symbol: nadE-2
gene_biotype: protein_coding
description:
  NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.


ensembl_gene_id: SBI_09007
symbol: SBI_09007
gene_biotype: protein_coding
description:
  COG4632 Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase.


ensembl_gene_id: SBI_09010
symbol: SBI_09010
gene_biotype: protein_coding
description:
  Mandelate racemase/muconate lactonizing protein; COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily.


ensembl_gene_id: SBI_09016
symbol: SBI_09016
gene_biotype: protein_coding
description:
  HlyB/MsbA family ABC transporter; COG1132 ABC-type multidrug transport system, ATPase and permease components.


ensembl_gene_id: SBI_09025
symbol: SBI_09025
gene_biotype: protein_coding
description:
  Aminotransferase; COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase.


ensembl_gene_id: SBI_09037
symbol: SBI_09037
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog).


ensembl_gene_id: SBI_09039
symbol: SBI_09039
gene_biotype: protein_coding
description:
  Integral membrane sensor protein; COG3290 Signal transduction histidine kinase regulating citrate/malate metabolism.


ensembl_gene_id: SBI_09043
symbol: SBI_09043
gene_biotype: protein_coding
description:
  Putative oxidoreductase; COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases.


ensembl_gene_id: SBI_09050
symbol: SBI_09050
gene_biotype: protein_coding
description:
  ABC-2 type transporter superfamily protein; COG0842 ABC-type multidrug transport system, permease component.


ensembl_gene_id: SBI_09057
symbol: SBI_09057
gene_biotype: protein_coding
description:
  Putative non-ribosomal peptide synthase; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II.


ensembl_gene_id: SBI_09077
symbol: plsC6
gene_biotype: protein_coding
description:
  1-acylglycerol-3-phosphate O-acyltransferase; COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase.


ensembl_gene_id: SBI_09094
symbol: SBI_09094
gene_biotype: protein_coding
description:
  Ubiquinone biosynthesis O-methyltransferase; COG2227 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase.


ensembl_gene_id: SBI_09098
symbol: SBI_09098
gene_biotype: protein_coding
description:
  LuxR family two-component response regulator; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: SBI_09102
symbol: SBI_09102
gene_biotype: protein_coding
description:
  Putative zinc-containing dehydrogenase; COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases.


ensembl_gene_id: SBI_09103
symbol: SBI_09103
gene_biotype: protein_coding
description:
  Putative stress-inducible protein; COG0589 Universal stress protein UspA and related nucleotide-binding proteins.


ensembl_gene_id: SBI_09108
symbol: glpK
gene_biotype: protein_coding
description:
  Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.


ensembl_gene_id: SBI_09118
symbol: SBI_09118
gene_biotype: protein_coding
description:
  Arginine ABC transporter periplasmic substrate-binding protein; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain.


ensembl_gene_id: SBI_09120
symbol: SBI_09120
gene_biotype: protein_coding
description:
  Arginine/ornithine transport ATP-binding protein; COG1126 ABC-type polar amino acid transport system, ATPase component.


ensembl_gene_id: SBI_09139
symbol: SBI_09139
gene_biotype: protein_coding
description:
  Stress protein; COG2310 Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1.


ensembl_gene_id: SBI_09168
symbol: SBI_09168
gene_biotype: protein_coding
description:
  Amidohydrolase family protein; COG1574 Predicted metal-dependent hydrolase with the TIM-barrel fold.


ensembl_gene_id: SBI_09178
symbol: argG-2
gene_biotype: protein_coding
description:
  COG0137 Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 2 subfamily.


ensembl_gene_id: SBI_09184
symbol: SBI_09184
gene_biotype: protein_coding
description:
  C4-dicarboxylate transport protein; COG1301 Na+/H+-dicarboxylate symporters; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: SBI_09192
symbol: SBI_09192
gene_biotype: protein_coding
description:
  Carboxylesterase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: SBI_09215
symbol: SBI_09215
gene_biotype: protein_coding
description:
  Oxygenase; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: SBI_09236
symbol: SBI_09236
gene_biotype: protein_coding
description:
  Surfactin synthetase thioesterase subunit; COG3208 Predicted thioesterase involved in non-ribosomal peptide biosynthesis.


ensembl_gene_id: SBI_09267
symbol: SBI_09267
gene_biotype: protein_coding
description:
  Two-component system, OmpR family, sensor histidine kinase KdpD; COG2205 Osmosensitive K+ channel histidine kinase.


ensembl_gene_id: SBI_09271
symbol: kdpC-2
gene_biotype: protein_coding
description:
  Putative cation transport ATPase component; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.


ensembl_gene_id: SBI_09274
symbol: SBI_09274
gene_biotype: protein_coding
description:
  Putative binding-protein dependent transport system integral membrane component; COG0395 ABC-type sugar transport system, permease component.


ensembl_gene_id: SBI_09276
symbol: SBI_09276
gene_biotype: protein_coding
description:
  Substrate-binding transport protein; COG1653 ABC-type sugar transport system, periplasmic component.


ensembl_gene_id: SBI_09277
symbol: SBI_09277
gene_biotype: protein_coding
description:
  Putative 2-hydroxyacid family dehydrogenase; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases.


ensembl_gene_id: SBI_09280
symbol: SBI_09280
gene_biotype: protein_coding
description:
  2Fe-2S cluster-containing protein; COG2220 Predicted Zn-dependent hydrolases of the beta-lactamase fold.


ensembl_gene_id: SBI_09282
symbol: SBI_09282
gene_biotype: protein_coding
description:
  Two component system response regulator; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: SBI_09288
symbol: SBI_09288
gene_biotype: protein_coding
description:
  Phosphotriesterase-family protein; COG1735 Predicted metal-dependent hydrolase with the TIM-barrel fold.


ensembl_gene_id: SBI_09302
symbol: SBI_09302
gene_biotype: protein_coding
description:
  CRP-like regulatory protein; COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases.


ensembl_gene_id: SBI_09304
symbol: SBI_09304
gene_biotype: protein_coding
description:
  Putative luxR family two-component response regulator; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: SBI_09307
symbol: SBI_09307
gene_biotype: protein_coding
description:
  Tellurite resistance protein TerA; COG2310 Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1.


ensembl_gene_id: SBI_09312
symbol: SBI_09312
gene_biotype: protein_coding
description:
  Siderophore 2,3-dihydroxybenzoate-glycine-threonine trimeric ester bacillibactin synthetase; COG1020 Non-ribosomal peptide synthetase modules and related proteins.


ensembl_gene_id: SBI_09339
symbol: SBI_09339
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases.


ensembl_gene_id: SBI_09358
symbol: SBI_09358
gene_biotype: protein_coding
description:
  Putative aldo/keto reductase; COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases).


ensembl_gene_id: SBI_09396
symbol: SBI_09396
gene_biotype: protein_coding
description:
  Putative ABC transporter substrate-binding protein; COG1653 ABC-type sugar transport system, periplasmic component.


ensembl_gene_id: SBI_09418
symbol: sig57
gene_biotype: protein_coding
description:
  Putative sigma factor; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family.


ensembl_gene_id: SBI_09446
symbol: SBI_09446
gene_biotype: protein_coding
description:
  Putative glycosyltransferase; COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase.


ensembl_gene_id: SBI_09447
symbol: SBI_09447
gene_biotype: protein_coding
description:
  Putative dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.


ensembl_gene_id: SBI_09457
symbol: SBI_09457
gene_biotype: protein_coding
description:
  Putative sugar ABC transporter sugar-binding protein; COG4213 ABC-type xylose transport system, periplasmic component.


ensembl_gene_id: SBI_09459
symbol: SBI_09459
gene_biotype: protein_coding
description:
  Inner-membrane translocator; COG4214 ABC-type xylose transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: SBI_09462
symbol: SBI_09462
gene_biotype: protein_coding
description:
  Putative sulfonate ABC transporter, sulfonate-binding protein; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components.


ensembl_gene_id: SBI_09465
symbol: SBI_09465
gene_biotype: protein_coding
description:
  Putative monooxigenase; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: SBI_09467
symbol: SBI_09467
gene_biotype: protein_coding
description:
  Uncharacterized peroxidase-related enzyme; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.


ensembl_gene_id: SBI_09468
symbol: SBI_09468
gene_biotype: protein_coding
description:
  Luciferase-like monooxygenase; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: SBI_09471
symbol: SBI_09471
gene_biotype: protein_coding
description:
  Inner-membrane translocator; COG0559 Branched-chain amino acid ABC-type transport system, permease components; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: SBI_09485
symbol: SBI_09485
gene_biotype: protein_coding
description:
  Putative peptide transporter; COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components.


ensembl_gene_id: SBI_09486
symbol: SBI_09486
gene_biotype: protein_coding
description:
  ABC peptide transporter, ATP-binding component; COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase; Belongs to the ABC transporter superfamily.


ensembl_gene_id: SBI_09487
symbol: SBI_09487
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase.


ensembl_gene_id: SBI_09504
symbol: SBI_09504
gene_biotype: protein_coding
description:
  Hypothetical protein; COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases.


ensembl_gene_id: SBI_09505
symbol: SBI_09505
gene_biotype: protein_coding
description:
  Short-chain dehydrogenase/reductase SDR; COG0300 Short-chain dehydrogenases of various substrate specificities; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: SBI_09515
symbol: SBI_09515
gene_biotype: protein_coding
description:
  Putative permease of a carbohydrate transport system; COG1457 Purine-cytosine permease and related proteins; Belongs to the purine-cytosine permease (2.A.39) family.


