# geneInfo

ensembl_gene_id: BDGL_000011
symbol: nrdB
gene_biotype: protein_coding
description:
  Ribonucleoside-diphosphate reductase, beta subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.


ensembl_gene_id: BDGL_000013
symbol: nrdA
gene_biotype: protein_coding
description:
  Ribonucleoside diphosphate reductase, alpha subunit; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.


ensembl_gene_id: BDGL_000018
symbol: nuoA
gene_biotype: protein_coding
description:
  NADH dehydrogenase I chain A; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.


ensembl_gene_id: BDGL_000019
symbol: nuoB
gene_biotype: protein_coding
description:
  NADH dehydrogenase I chain B; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: BDGL_000020
symbol: nuoCD
gene_biotype: protein_coding
description:
  NADH dehydrogenase I chain C,D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family.


ensembl_gene_id: BDGL_000022
symbol: nuoF
gene_biotype: protein_coding
description:
  NADH dehydrogenase I chain F; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family.


ensembl_gene_id: BDGL_000023
symbol: nuoG
gene_biotype: protein_coding
description:
  NADH dehydrogenase I chain G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family.


ensembl_gene_id: BDGL_000024
symbol: nuoH
gene_biotype: protein_coding
description:
  NADH dehydrogenase I chain H; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.


ensembl_gene_id: BDGL_000026
symbol: nuoJ
gene_biotype: protein_coding
description:
  NADH dehydrogenase I chain J; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: BDGL_000027
symbol: nuoK
gene_biotype: protein_coding
description:
  NADH-quinone oxidoreductase chain K; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family.


ensembl_gene_id: BDGL_000030
symbol: nuoN
gene_biotype: protein_coding
description:
  NADH dehydrogenase I chain N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family.


ensembl_gene_id: BDGL_000031
symbol: upp
gene_biotype: protein_coding
description:
  Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.


ensembl_gene_id: BDGL_000047
symbol: metG
gene_biotype: protein_coding
description:
  methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.


ensembl_gene_id: BDGL_000049
symbol: mrp
gene_biotype: protein_coding
description:
  Putative ATP-binding protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.


ensembl_gene_id: BDGL_000060
symbol: dusC
gene_biotype: protein_coding
description:
  tRNA-dihydrouridine synthase C; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs. Belongs to the Dus family. DusC subfamily.


ensembl_gene_id: BDGL_000063
symbol: ffh
gene_biotype: protein_coding
description:
  4.5S-RNP protein, GTP binding export factor, part of signal recognition particle with 4.5 RNA; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissoci [...]


ensembl_gene_id: BDGL_000064
symbol: coaX
gene_biotype: protein_coding
description:
  Type III pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.


ensembl_gene_id: BDGL_000068
symbol: smc
gene_biotype: protein_coding
description:
  Putative chromosome segregation ATPase; Required for chromosome condensation and partitioning. Belongs to the SMC family.


ensembl_gene_id: BDGL_000069
symbol: zipA
gene_biotype: protein_coding
description:
  Putative cell division protein; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins. Belongs to the ZipA family.


ensembl_gene_id: BDGL_000070
symbol: ligA
gene_biotype: protein_coding
description:
  DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily.


ensembl_gene_id: BDGL_000071
symbol: bfrA
gene_biotype: protein_coding
description:
  Bacterioferritin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family.


ensembl_gene_id: BDGL_000074
symbol: otsB
gene_biotype: protein_coding
description:
  Trehalose-6-phosphate phophatase; Removes the phosphate from trehalose 6-phosphate to produce free trehalose.


ensembl_gene_id: BDGL_000076
symbol: bioA
gene_biotype: protein_coding
description:
  Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.


ensembl_gene_id: BDGL_000078
symbol: bioC
gene_biotype: protein_coding
description:
  Putative biotin biosynthesis protein; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.


ensembl_gene_id: BDGL_000079
symbol: bioD
gene_biotype: protein_coding
description:
  Dethiobiotin synthetase (dethiobiotin synthase); Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.


ensembl_gene_id: BDGL_000080
symbol: rluB
gene_biotype: protein_coding
description:
  Putative ribosomal large subunit pseudouridine synthase B; Belongs to the pseudouridine synthase RsuA family.


ensembl_gene_id: BDGL_000081
symbol: ADY80667.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.


ensembl_gene_id: BDGL_000082
symbol: ADY80668.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.


ensembl_gene_id: BDGL_000088
symbol: fabG
gene_biotype: protein_coding
description:
  3-oxoacyl-[acyl-carrier-protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: BDGL_000093
symbol: ribB
gene_biotype: protein_coding
description:
  3,4 dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.


ensembl_gene_id: BDGL_000097
symbol: panD
gene_biotype: protein_coding
description:
  Aspartate 1-decarboxylase precursor; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.


ensembl_gene_id: BDGL_000098
symbol: pth
gene_biotype: protein_coding
description:
  peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.


ensembl_gene_id: BDGL_000099
symbol: rplY
gene_biotype: protein_coding
description:
  50S ribosomal protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family.


ensembl_gene_id: BDGL_000100
symbol: prs
gene_biotype: protein_coding
description:
  Ribose-phosphate pyrophosphokinase (phosphoribosyl pyrophosphate synthetase); Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.


ensembl_gene_id: BDGL_000101
symbol: ispE
gene_biotype: protein_coding
description:
  4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.


ensembl_gene_id: BDGL_000102
symbol: lolB
gene_biotype: protein_coding
description:
  Outer-membrane lipoprotein precursor; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.


ensembl_gene_id: BDGL_000104
symbol: hemA
gene_biotype: protein_coding
description:
  Glutamyl tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).


ensembl_gene_id: BDGL_000106
symbol: dnaG
gene_biotype: protein_coding
description:
  DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Belongs to the DnaG primase family.


ensembl_gene_id: BDGL_000107
symbol: comL
gene_biotype: protein_coding
description:
  Putative competence protein (ComL); Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: BDGL_000108
symbol: rluD
gene_biotype: protein_coding
description:
  Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.


ensembl_gene_id: BDGL_000111
symbol: smpB
gene_biotype: protein_coding
description:
  SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]


ensembl_gene_id: BDGL_000112
symbol: coaD
gene_biotype: protein_coding
description:
  Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.


ensembl_gene_id: BDGL_000119
symbol: yeaW
gene_biotype: protein_coding
description:
  Dioxygenase, alpha subunit; Converts carnitine to trimethylamine and malic semialdehyde. Acts on both enantiomers; Belongs to the bacterial ring-hydroxylating dioxygenase alpha subunit family. CntA subfamily.


ensembl_gene_id: BDGL_000121
symbol: yeaX
gene_biotype: protein_coding
description:
  Putative dioxygenase beta subunit; Converts carnitine to trimethylamine and malic semialdehyde. Acts on both enantiomers; Belongs to the PDR/VanB family. CntB subfamily.


ensembl_gene_id: BDGL_000124
symbol: nadE2
gene_biotype: protein_coding
description:
  Putative glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.


ensembl_gene_id: BDGL_000127
symbol: fabB
gene_biotype: protein_coding
description:
  beta-ketoacyl-ACP synthase I (3-oxoacyl-[acyl-carrier-protein] synthase I); Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: BDGL_000129
symbol: rpsL
gene_biotype: protein_coding
description:
  30S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.


ensembl_gene_id: BDGL_000130
symbol: rpsG
gene_biotype: protein_coding
description:
  30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.


ensembl_gene_id: BDGL_000131
symbol: fusA
gene_biotype: protein_coding
description:
  Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.


ensembl_gene_id: BDGL_000132
symbol: tuf1
gene_biotype: protein_coding
description:
  Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.


ensembl_gene_id: BDGL_000135
symbol: rimI
gene_biotype: protein_coding
description:
  Ribosomal-protein-alanine acetyltransferase; Acetylates the N-terminal alanine of ribosomal protein S18.


ensembl_gene_id: BDGL_000136
symbol: ate
gene_biotype: protein_coding
description:
  Putative arginine-tRNA-protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate. Belongs to the R-transferase family. Bpt subfamily.


ensembl_gene_id: BDGL_000137
symbol: aat
gene_biotype: protein_coding
description:
  Leucyl, phenylalanyl-tRNA-protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.


ensembl_gene_id: BDGL_000143
symbol: minE
gene_biotype: protein_coding
description:
  Cell division topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.


ensembl_gene_id: BDGL_000145
symbol: minC
gene_biotype: protein_coding
description:
  Cell division inhibitor, inhibits FtsZ ring formation; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family.


ensembl_gene_id: BDGL_000149
symbol: rep
gene_biotype: protein_coding
description:
  ATP-dependent DNA helicase; Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.


ensembl_gene_id: BDGL_000150
symbol: dut
gene_biotype: protein_coding
description:
  Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.


ensembl_gene_id: BDGL_000152
symbol: argB
gene_biotype: protein_coding
description:
  Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.


ensembl_gene_id: BDGL_000158
symbol: omlA
gene_biotype: protein_coding
description:
  Outer membrane lipoprotein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: BDGL_000162
symbol: yggS
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.


ensembl_gene_id: BDGL_000164
symbol: sbcD
gene_biotype: protein_coding
description:
  ATP-dependent dsDNA exonuclease; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.


ensembl_gene_id: BDGL_000174
symbol: emrB-2
gene_biotype: protein_coding
description:
  Multidrug resistance transmembrane protein (MFS superfamily); Belongs to the major facilitator superfamily.


ensembl_gene_id: BDGL_000180
symbol: hsdR
gene_biotype: protein_coding
description:
  HsdR protein probable type I restriction enzyme restriction chain; Subunit R is required for both nuclease and ATPase activities, but not for modification.


ensembl_gene_id: BDGL_000188
symbol: cynR
gene_biotype: protein_coding
description:
  Transcription activator of glutamate synthase(LysR family); Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: BDGL_000204
symbol: betA
gene_biotype: protein_coding
description:
  Choline dehydrogenase, a flavoprotein; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.


ensembl_gene_id: BDGL_000205
symbol: betB
gene_biotype: protein_coding
description:
  NAD+-dependent betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid.


ensembl_gene_id: BDGL_000207
symbol: betT
gene_biotype: protein_coding
description:
  Putative choline/carnitine/betaine transporter family protein; Belongs to the BCCT transporter (TC 2.A.15) family.


ensembl_gene_id: BDGL_000213
symbol: dctA1
gene_biotype: protein_coding
description:
  Aerobic C4-dicarboxylate transport protein; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: BDGL_000226
symbol: ADY80812.1
gene_biotype: protein_coding
description:
  3-ketoacyl-(acyl-carrier-protein) reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: BDGL_000233
symbol: nadX
gene_biotype: protein_coding
description:
  L-aspartate dehydrogenase; Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.


ensembl_gene_id: BDGL_000239
symbol: def2
gene_biotype: protein_coding
description:
  Peptide deformylase 2; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.


ensembl_gene_id: BDGL_000251
symbol: metH-2
gene_biotype: protein_coding
description:
  Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.


ensembl_gene_id: BDGL_000259
symbol: nfuA
gene_biotype: protein_coding
description:
  Putative membrane-bound protein in GNT I transport system (GntY); Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.


ensembl_gene_id: BDGL_000269
symbol: mtgA
gene_biotype: protein_coding
description:
  Monofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family.


ensembl_gene_id: BDGL_000270
symbol: ppk
gene_biotype: protein_coding
description:
  Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family.


ensembl_gene_id: BDGL_000273
symbol: estR
gene_biotype: protein_coding
description:
  Esterase operon transcriptional regulator (LysR family); Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: BDGL_000283
symbol: cysNC
gene_biotype: protein_coding
description:
  ATP-sulfurylase, subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.


ensembl_gene_id: BDGL_000288
symbol: nahR
gene_biotype: protein_coding
description:
  Putative LysR family transcriptional regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: BDGL_000292
symbol: ureD
gene_biotype: protein_coding
description:
  Urease accessory protein; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.


ensembl_gene_id: BDGL_000297
symbol: ureE
gene_biotype: protein_coding
description:
  Urease accessory protein UreE; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family.


ensembl_gene_id: BDGL_000299
symbol: ureG
gene_biotype: protein_coding
description:
  Urease accessory protein; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.


ensembl_gene_id: BDGL_000301
symbol: rsmD
gene_biotype: protein_coding
description:
  Putative methyltransferase; Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle; Belongs to the methyltransferase superfamily. RsmD family.


ensembl_gene_id: BDGL_000302
symbol: pbpA
gene_biotype: protein_coding
description:
  Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.


ensembl_gene_id: BDGL_000305
symbol: adk
gene_biotype: protein_coding
description:
  Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.


ensembl_gene_id: BDGL_000307
symbol: nth
gene_biotype: protein_coding
description:
  Endonuclease III DNA glycosylase/apyrimidinic (AP) lyase; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.


ensembl_gene_id: BDGL_000308
symbol: rnfB
gene_biotype: protein_coding
description:
  Putative iron-sulfur protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.


ensembl_gene_id: BDGL_000312
symbol: rlmH
gene_biotype: protein_coding
description:
  Hypothetical protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family.


ensembl_gene_id: BDGL_000313
symbol: lon
gene_biotype: protein_coding
description:
  DNA-binding ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.


ensembl_gene_id: BDGL_000314
symbol: ADY80900.1
gene_biotype: protein_coding
description:
  5-formyltetrahydrofolate cyclo-ligase family protein; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.


ensembl_gene_id: BDGL_000328
symbol: iciA
gene_biotype: protein_coding
description:
  Chromosome replication initiation inhibitor protein; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: BDGL_000330
symbol: rsmI
gene_biotype: protein_coding
description:
  Putative methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.


ensembl_gene_id: BDGL_000344
symbol: rnt
gene_biotype: protein_coding
description:
  Ribonuclease T (degrades tRNA, has exonuclease and ssDNAse activity); Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.


ensembl_gene_id: BDGL_000364
symbol: rmpR
gene_biotype: protein_coding
description:
  GntR family transcriptional regulator, transcriptional repressor for pyruvate dehydrogenase complex.


ensembl_gene_id: BDGL_000368
symbol: astC
gene_biotype: protein_coding
description:
  Succinylornithine transaminase (also has acetylornitine transaminase activity, PLP-dependent); Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.


ensembl_gene_id: BDGL_000405
symbol: ephD
gene_biotype: protein_coding
description:
  Putative short-chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: BDGL_000420
symbol: add
gene_biotype: protein_coding
description:
  Adenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.


ensembl_gene_id: BDGL_000424
symbol: csrA
gene_biotype: protein_coding
description:
  Carbon storage regulator; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).


ensembl_gene_id: BDGL_000426
symbol: alaS
gene_biotype: protein_coding
description:
  alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.


ensembl_gene_id: BDGL_000427
symbol: epD
gene_biotype: protein_coding
description:
  D-erythrose 4-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.


ensembl_gene_id: BDGL_000428
symbol: hisZ
gene_biotype: protein_coding
description:
  ATP phosphoribosyltransferase; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.


ensembl_gene_id: BDGL_000429
symbol: purA
gene_biotype: protein_coding
description:
  Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.


ensembl_gene_id: BDGL_000438
symbol: clpB
gene_biotype: protein_coding
description:
  ATP-dependent protease; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.


ensembl_gene_id: BDGL_000441
symbol: ycbY
gene_biotype: protein_coding
description:
  Putative N-6 adenine-specific DNA methylase; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family.


ensembl_gene_id: BDGL_000443
symbol: pyrB
gene_biotype: protein_coding
description:
  Aspartate carbamoyltransferase, catalytic subunit; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.


ensembl_gene_id: BDGL_000449
symbol: trmB
gene_biotype: protein_coding
description:
  tRNA(guanine-7)methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.


ensembl_gene_id: BDGL_000457
symbol: ahpC
gene_biotype: protein_coding
description:
  Alkyl hydroperoxide reductase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.


ensembl_gene_id: BDGL_000463
symbol: benD
gene_biotype: protein_coding
description:
  1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: BDGL_000470
symbol: mphP
gene_biotype: protein_coding
description:
  Phenol 2-monooxygenase; Catabolizes phenol, and some of its methylated derivatives. P5 is required for growth on phenol, and for in vitro phenol hydroxylase activity (By similarity).


ensembl_gene_id: BDGL_000474
symbol: mphL
gene_biotype: protein_coding
description:
  Phenol 2-monooxygenase; Catabolizes phenol, and some of its methylated derivatives. P1 is required for growth on phenol, and for in vitro phenol hydroxylase activity (By similarity).


ensembl_gene_id: BDGL_000487
symbol: xseA
gene_biotype: protein_coding
description:
  Putative exodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family.


ensembl_gene_id: BDGL_000494
symbol: htrB
gene_biotype: protein_coding
description:
  Lipid A biosynthesis lauroyl acyltransferase (heat shock protein B); Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A).


ensembl_gene_id: BDGL_000497
symbol: proC
gene_biotype: protein_coding
description:
  Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.


ensembl_gene_id: BDGL_000522
symbol: kdsC
gene_biotype: protein_coding
description:
  3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) phosphatase; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family.


ensembl_gene_id: BDGL_000524
symbol: lptA
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.


ensembl_gene_id: BDGL_000536
symbol: fdxA
gene_biotype: protein_coding
description:
  7-Fe ferredoxin; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.


ensembl_gene_id: BDGL_000538
symbol: mutS
gene_biotype: protein_coding
description:
  DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.


ensembl_gene_id: BDGL_000539
symbol: ADY81125.1
gene_biotype: protein_coding
description:
  Putative aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: BDGL_000554
symbol: srpA
gene_biotype: protein_coding
description:
  Catalase-like protein; Has an organic peroxide-dependent peroxidase activity. Belongs to the catalase family.


ensembl_gene_id: BDGL_000599
symbol: pxpA
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.


ensembl_gene_id: BDGL_000665
symbol: queH
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).


ensembl_gene_id: BDGL_000692
symbol: paaK
gene_biotype: protein_coding
description:
  phenylacetyl-CoA ligase; Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).


ensembl_gene_id: BDGL_000713
symbol: azoR4
gene_biotype: protein_coding
description:
  (acyl-carrier protein) phosphodiesterase; Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity; Belongs to the azoreductase type 1 family.


ensembl_gene_id: BDGL_000716
symbol: alr2
gene_biotype: protein_coding
description:
  Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.


ensembl_gene_id: BDGL_000719
symbol: cysA2
gene_biotype: protein_coding
description:
  ABC-type spermidine/putrescine transport system, ATPase component; Belongs to the ABC transporter superfamily.


ensembl_gene_id: BDGL_000722
symbol: phnW
gene_biotype: protein_coding
description:
  Aminotransferase, class V; Involved in phosphonate degradation; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.


ensembl_gene_id: BDGL_000723
symbol: phnX
gene_biotype: protein_coding
description:
  Phosphonoacetaldehyde hydrolase; Involved in phosphonate degradation; Belongs to the HAD-like hydrolase superfamily. PhnX family.


ensembl_gene_id: BDGL_000775
symbol: ADY81361.1
gene_biotype: protein_coding
description:
  Signal transduction histidine kinase containing a receiver domain (hybrid) and a purine-cytosine permease domain.


ensembl_gene_id: BDGL_000784
symbol: glnH-2
gene_biotype: protein_coding
description:
  Putative ABC transporter, periplasmic binding protein, amino acid; Belongs to the bacterial solute-binding protein 3 family.


ensembl_gene_id: BDGL_000788
symbol: ADY81374.1
gene_biotype: protein_coding
description:
  Putative cysteine desulfurase 1 (Csd); Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: BDGL_000807
symbol: mdcB
gene_biotype: protein_coding
description:
  triphosphoribosyl-dephospho-CoA synthase; Involved in the formation of 2-(5''-phosphoribosyl)-3'- dephosphocoenzyme-A, the prosthetic group of the acyl-carrier protein of the malonate decarboxylase; Belongs to the CitG/MdcB family.


ensembl_gene_id: BDGL_000808
symbol: mdcC
gene_biotype: protein_coding
description:
  Malonate decarboxylase, delta subunit; Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism.


ensembl_gene_id: BDGL_000815
symbol: mdcR
gene_biotype: protein_coding
description:
  Transcriptional regulator for malonate utilization (LysR family); Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: BDGL_000845
symbol: trmJ
gene_biotype: protein_coding
description:
  Putative tRNA/rRNA methyltransferase; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.


ensembl_gene_id: BDGL_000848
symbol: dctA
gene_biotype: protein_coding
description:
  Sodium--dicarboxylate symporter; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: BDGL_000855
symbol: glnD
gene_biotype: protein_coding
description:
  Uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.


ensembl_gene_id: BDGL_000856
symbol: purT
gene_biotype: protein_coding
description:
  Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family.


ensembl_gene_id: BDGL_000864
symbol: ychF
gene_biotype: protein_coding
description:
  Translation-associated GTPase; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.


ensembl_gene_id: BDGL_000866
symbol: metN1
gene_biotype: protein_coding
description:
  D-methionine ABC transporter, ATP-binding protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.


ensembl_gene_id: BDGL_000884
symbol: oxyR
gene_biotype: protein_coding
description:
  Putative transcriptional regulator (LysR family); Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: BDGL_000896
symbol: bioB
gene_biotype: protein_coding
description:
  Biotin synthetase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.


ensembl_gene_id: BDGL_000897
symbol: queG
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family.


ensembl_gene_id: BDGL_000898
symbol: yjeF
gene_biotype: protein_coding
description:
  YjeF-like protein/carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. In the C-terminal section; belongs to the NnrD/CARKD family.


ensembl_gene_id: BDGL_000900
symbol: ruvC
gene_biotype: protein_coding
description:
  Holliday junction nuclease; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.


ensembl_gene_id: BDGL_000909
symbol: tktA
gene_biotype: protein_coding
description:
  Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.


ensembl_gene_id: BDGL_000915
symbol: trmA
gene_biotype: protein_coding
description:
  tRNA (uracil-5-)-methyltransferase; Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).


ensembl_gene_id: BDGL_000917
symbol: putA
gene_biotype: protein_coding
description:
  Bifunctional protein putA; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: BDGL_000919
symbol: putP
gene_biotype: protein_coding
description:
  SSS family, major sodium/proline symporter; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: BDGL_000920
symbol: npdA
gene_biotype: protein_coding
description:
  NAD-dependent deacetylase (regulatory protein sirtuin family); Belongs to the sirtuin family. Class III subfamily.


ensembl_gene_id: BDGL_000921
symbol: gcvH
gene_biotype: protein_coding
description:
  Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.


ensembl_gene_id: BDGL_000927
symbol: sstT
gene_biotype: protein_coding
description:
  Transporter, sodium-dicarboxylate symporter family; Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system). Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: BDGL_000931
symbol: maf
gene_biotype: protein_coding
description:
  Septum formation protein; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.


ensembl_gene_id: BDGL_000935
symbol: fba
gene_biotype: protein_coding
description:
  Fructose-1,6-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.


ensembl_gene_id: BDGL_000936
symbol: surA
gene_biotype: protein_coding
description:
  Peptidyl-prolyl cis-trans isomerase; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.


ensembl_gene_id: BDGL_000937
symbol: ostA
gene_biotype: protein_coding
description:
  Organic solvent tolerance protein precursor; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.


ensembl_gene_id: BDGL_000940
symbol: gidB
gene_biotype: protein_coding
description:
  Glucose-inhibited division protein B (methyltransferase); Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.


ensembl_gene_id: BDGL_000945
symbol: msbA
gene_biotype: protein_coding
description:
  Lipid transport protein; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.


ensembl_gene_id: BDGL_000946
symbol: lpxK
gene_biotype: protein_coding
description:
  Tetraacyldisaccharide 4'-kinase (lipid A 4'-kinase); Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).


ensembl_gene_id: BDGL_000947
symbol: kdsB
gene_biotype: protein_coding
description:
  3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.


ensembl_gene_id: BDGL_000957
symbol: ung
gene_biotype: protein_coding
description:
  uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.


ensembl_gene_id: BDGL_000959
symbol: yfhC
gene_biotype: protein_coding
description:
  tRNA-specific adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.


ensembl_gene_id: BDGL_000962
symbol: rpsA
gene_biotype: protein_coding
description:
  30S ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.


ensembl_gene_id: BDGL_000963
symbol: himD
gene_biotype: protein_coding
description:
  Integration host factor (IHF),beta subunit, site specific recombination; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.


ensembl_gene_id: BDGL_000965
symbol: pyrF
gene_biotype: protein_coding
description:
  Orotidine-5'-phosphate decarboxylase (OMP decarboxylase); Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.


ensembl_gene_id: BDGL_000970
symbol: glcB
gene_biotype: protein_coding
description:
  Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.


ensembl_gene_id: BDGL_000975
symbol: tonB
gene_biotype: protein_coding
description:
  Periplasmic protein TonB; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.


ensembl_gene_id: BDGL_000986
symbol: cysQ
gene_biotype: protein_coding
description:
  3'(2'),5'-bisphosphate nucleotidase CysQ; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family.


ensembl_gene_id: BDGL_000990
symbol: menG
gene_biotype: protein_coding
description:
  Regulator of ribonuclease activity A; Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.


ensembl_gene_id: BDGL_000994
symbol: mfd
gene_biotype: protein_coding
description:
  Transcription-repair coupling protein; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.


ensembl_gene_id: BDGL_000998
symbol: hscA
gene_biotype: protein_coding
description:
  Chaperone protein HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.


ensembl_gene_id: BDGL_000999
symbol: hscB
gene_biotype: protein_coding
description:
  Co-chaperone protein (Hsc20), believed to be involved in assembly of Fe-S clusters; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family.


ensembl_gene_id: BDGL_001000
symbol: ADY81586.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system; Belongs to the HesB/IscA family.


ensembl_gene_id: BDGL_001001
symbol: nifU
gene_biotype: protein_coding
description:
  Nitrogen fixation protein NifU-like protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.


ensembl_gene_id: BDGL_001002
symbol: iscS
gene_biotype: protein_coding
description:
  Cysteine desulfurase used in synthesis of Fe-S cluster (tRNA 4-thiouridine sulfurtransferase); Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.


ensembl_gene_id: BDGL_001006
symbol: hup
gene_biotype: protein_coding
description:
  DNA-binding protein HU-beta; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.


ensembl_gene_id: BDGL_001018
symbol: cobU
gene_biotype: protein_coding
description:
  Adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.


ensembl_gene_id: BDGL_001019
symbol: cobT
gene_biotype: protein_coding
description:
  Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).


ensembl_gene_id: BDGL_001022
symbol: cobS
gene_biotype: protein_coding
description:
  Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.


ensembl_gene_id: BDGL_001023
symbol: aroF
gene_biotype: protein_coding
description:
  Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP).


ensembl_gene_id: BDGL_001030
symbol: lpxB
gene_biotype: protein_coding
description:
  Lipid A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: BDGL_001039
symbol: metZ
gene_biotype: protein_coding
description:
  O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.


ensembl_gene_id: BDGL_001041
symbol: ADY81627.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.


ensembl_gene_id: BDGL_001042
symbol: recR
gene_biotype: protein_coding
description:
  Recombination protein, gap repair; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.


ensembl_gene_id: BDGL_001044
symbol: azoR2
gene_biotype: protein_coding
description:
  Acyl carrier protein phosphodiesterase; Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity; Belongs to the azoreductase type 1 family.


ensembl_gene_id: BDGL_001053
symbol: trpB2
gene_biotype: protein_coding
description:
  Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.


ensembl_gene_id: BDGL_001054
symbol: prmB
gene_biotype: protein_coding
description:
  Putative adenine-specific methylase; Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue; Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.


ensembl_gene_id: BDGL_001055
symbol: aroC
gene_biotype: protein_coding
description:
  Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.


ensembl_gene_id: BDGL_001060
symbol: lipA
gene_biotype: protein_coding
description:
  Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.


ensembl_gene_id: BDGL_001064
symbol: acoD
gene_biotype: protein_coding
description:
  Dihydrolipoamide dehydrogenase (E3 component of pyruvate and 2-oxoglutarate dehydrogenase complexes).


ensembl_gene_id: BDGL_001065
symbol: budC
gene_biotype: protein_coding
description:
  Acetoin dehydrogenase (diacetyl reductase); Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: BDGL_001077
symbol: acpD
gene_biotype: protein_coding
description:
  Probable acyl carrier protein phosphodiesterase; Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity; Belongs to the azoreductase type 1 family.


ensembl_gene_id: BDGL_001094
symbol: thlA
gene_biotype: protein_coding
description:
  Putative acetyl-CoA acetyltransferase (acetoacetyl-CoA thiolase); Belongs to the thiolase-like superfamily. Thiolase family.


ensembl_gene_id: BDGL_001121
symbol: modB
gene_biotype: protein_coding
description:
  chlJ; Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: BDGL_001127
symbol: pqqB
gene_biotype: protein_coding
description:
  Pyrroloquinoline quinone biosynthesis protein PqqB; May be involved in the transport of PQQ or its precursor to the periplasm; Belongs to the PqqB family.


ensembl_gene_id: BDGL_001128
symbol: pqqC
gene_biotype: protein_coding
description:
  Pyrroloquinoline quinone biosynthesis protein PqqC; Ring cyclization and eight-electron oxidation of 3a-(2-amino- 2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9- dicarboxylic-acid to PQQ.


ensembl_gene_id: BDGL_001129
symbol: pqqD
gene_biotype: protein_coding
description:
  Pyrroloquinoline quinone biosynthesis protein PqqD; Functions as a PqqA binding protein and presents PqqA to PqqE, in the pyrroloquinoline quinone (PQQ) biosynthetic pathway.


ensembl_gene_id: BDGL_001130
symbol: pqqE
gene_biotype: protein_coding
description:
  Pyrroloquinoline quinone biosynthesis protein PqqE; Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).


ensembl_gene_id: BDGL_001135
symbol: acrE
gene_biotype: protein_coding
description:
  Secretion protein HlyD family protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: BDGL_001145
symbol: adhC
gene_biotype: protein_coding
description:
  Glutathione-dependent formaldehyde dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.


ensembl_gene_id: BDGL_001158
symbol: ADY81744.1
gene_biotype: protein_coding
description:
  Putative dipeptide transporter (ABC superfamily, ATP_bind); Belongs to the ABC transporter superfamily.


ensembl_gene_id: BDGL_001168
symbol: tatC
gene_biotype: protein_coding
description:
  Sec-independent protein secretion pathway, component C; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.


ensembl_gene_id: BDGL_001170
symbol: tatA
gene_biotype: protein_coding
description:
  Sec-independent protein secretion pathway, translocase protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.


ensembl_gene_id: BDGL_001247
symbol: ADY81833.1
gene_biotype: protein_coding
description:
  Putative iron transport protein (ABC superfamily, membrane); Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: BDGL_001265
symbol: aptA
gene_biotype: protein_coding
description:
  Beta alanine--pyruvate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: BDGL_001276
symbol: pgdH
gene_biotype: protein_coding
description:
  Putative D-3-phosphoglycerate dehydrogenase (PgdH); Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: BDGL_001298
symbol: fox2
gene_biotype: protein_coding
description:
  Short-chain dehydrogenase/reductase SDR; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: BDGL_001323
symbol: catB
gene_biotype: protein_coding
description:
  Muconate cycloisomerase I (cis,cis-muconate lactonizing enzyme I) (MLE); Belongs to the mandelate racemase/muconate lactonizing enzyme family.


ensembl_gene_id: BDGL_001362
symbol: quiB
gene_biotype: protein_coding
description:
  3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family.


ensembl_gene_id: BDGL_001372
symbol: ispD
gene_biotype: protein_coding
description:
  2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).


ensembl_gene_id: BDGL_001373
symbol: ftsB
gene_biotype: protein_coding
description:
  Putative cell division protein (FtsB-like); Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.


ensembl_gene_id: BDGL_001377
symbol: eno
gene_biotype: protein_coding
description:
  Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.


ensembl_gene_id: BDGL_001379
symbol: pyrG
gene_biotype: protein_coding
description:
  CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.


ensembl_gene_id: BDGL_001391
symbol: clpS
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease adaptor protein ClpS; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family.


ensembl_gene_id: BDGL_001393
symbol: argC
gene_biotype: protein_coding
description:
  N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.


ensembl_gene_id: BDGL_001396
symbol: rpiA
gene_biotype: protein_coding
description:
  Ribose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.


ensembl_gene_id: BDGL_001397
symbol: ilvA
gene_biotype: protein_coding
description:
  Threonine dehydratase biosynthetic (threonine deaminase); Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.


ensembl_gene_id: BDGL_001400
symbol: pldA
gene_biotype: protein_coding
description:
  Putative phospholipase A1 precursor; Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities. Belongs to the phospholipase A1 family.


ensembl_gene_id: BDGL_001410
symbol: ftsY
gene_biotype: protein_coding
description:
  Cell division protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.


ensembl_gene_id: BDGL_001416
symbol: argD
gene_biotype: protein_coding
description:
  Acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.


ensembl_gene_id: BDGL_001420
symbol: map
gene_biotype: protein_coding
description:
  Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.


ensembl_gene_id: BDGL_001421
symbol: braZ
gene_biotype: protein_coding
description:
  Branched chain amino acid transporter; Component of the transport system for branched-chain amino acids.


ensembl_gene_id: BDGL_001438
symbol: kynU
gene_biotype: protein_coding
description:
  L-kynurenine hydrolase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively.


ensembl_gene_id: BDGL_001444
symbol: recA
gene_biotype: protein_coding
description:
  Recombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.


ensembl_gene_id: BDGL_001448
symbol: lpxA2
gene_biotype: protein_coding
description:
  UDP-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: BDGL_001449
symbol: fabZ
gene_biotype: protein_coding
description:
  (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.


ensembl_gene_id: BDGL_001450
symbol: lpxD
gene_biotype: protein_coding
description:
  UDP-3-O-[3-hydroxylauroyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily.


ensembl_gene_id: BDGL_001452
symbol: yaeT
gene_biotype: protein_coding
description:
  Putative outer membrane protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: BDGL_001455
symbol: dxr
gene_biotype: protein_coding
description:
  1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family.


ensembl_gene_id: BDGL_001457
symbol: ispU
gene_biotype: protein_coding
description:
  Undecaprenyl pyrophosphate synthetase (di-trans,poly-cis-decaprenylcistransferase); Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.


ensembl_gene_id: BDGL_001458
symbol: frr
gene_biotype: protein_coding
description:
  Ribosome releasing factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.


ensembl_gene_id: BDGL_001460
symbol: yliG
gene_biotype: protein_coding
description:
  MiaB-like tRNA modifying enzyme YliG; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily.


ensembl_gene_id: BDGL_001463
symbol: glnG
gene_biotype: protein_coding
description:
  Response regulator in two-component regulatory system with GlnL, nitrogen regulation (EBP family); Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.


ensembl_gene_id: BDGL_001465
symbol: argF
gene_biotype: protein_coding
description:
  Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.


ensembl_gene_id: BDGL_001467
symbol: ispF
gene_biotype: protein_coding
description:
  2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).


ensembl_gene_id: BDGL_001475
symbol: fumC
gene_biotype: protein_coding
description:
  Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.


ensembl_gene_id: BDGL_001484
symbol: moeA
gene_biotype: protein_coding
description:
  Molybdopterin biosynthesis protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.


ensembl_gene_id: BDGL_001488
symbol: moaA
gene_biotype: protein_coding
description:
  Molybdopterin biosynthesis, protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.


ensembl_gene_id: BDGL_001489
symbol: fdhA
gene_biotype: protein_coding
description:
  Molybdopterin oxidoreductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: BDGL_001490
symbol: mobA
gene_biotype: protein_coding
description:
  Molybdopterin-guanine dinucleotide synthase; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family.


ensembl_gene_id: BDGL_001491
symbol: nasA
gene_biotype: protein_coding
description:
  Nitrate reductase, large subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.


ensembl_gene_id: BDGL_001493
symbol: nasB
gene_biotype: protein_coding
description:
  nasD; Nitrite reductase, large subunit, nucleotide-and Fe/S-cluster binding protein; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.


ensembl_gene_id: BDGL_001505
symbol: aroQ
gene_biotype: protein_coding
description:
  3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.


ensembl_gene_id: BDGL_001506
symbol: accB
gene_biotype: protein_coding
description:
  Biotin carboxyl carrier protein of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.


ensembl_gene_id: BDGL_001507
symbol: accC
gene_biotype: protein_coding
description:
  Biotin carboxylase (A subunit of acetyl-CoA carboxylase); This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.


ensembl_gene_id: BDGL_001520
symbol: ptpA
gene_biotype: protein_coding
description:
  Putative phosphotyrosine protein phosphatase (PtpA); Belongs to the low molecular weight phosphotyrosine protein phosphatase family.


ensembl_gene_id: BDGL_001527
symbol: dnaX
gene_biotype: protein_coding
description:
  DNA polymerase III, tau and gamma subunits (DNA elongation factor III); DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.


ensembl_gene_id: BDGL_001538
symbol: tal
gene_biotype: protein_coding
description:
  Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 1 subfamily.


ensembl_gene_id: BDGL_001569
symbol: ADY82155.1
gene_biotype: protein_coding
description:
  Monofunctional chorismate mutase precursor (CM-F); Catalyzes the Claisen rearrangement of chorismate to prephenate.


ensembl_gene_id: BDGL_001581
symbol: thiM
gene_biotype: protein_coding
description:
  Hydoxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family.


ensembl_gene_id: BDGL_001594
symbol: ppiB
gene_biotype: protein_coding
description:
  Peptidyl-prolyl cis-trans isomerase precursor; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.


ensembl_gene_id: BDGL_001595
symbol: lpxH
gene_biotype: protein_coding
description:
  UDP-2,3-diacylglucosamine hydrolase; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: BDGL_001599
symbol: hfq
gene_biotype: protein_coding
description:
  Uncharacterized host factor I protein; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.


ensembl_gene_id: BDGL_001600
symbol: miaA
gene_biotype: protein_coding
description:
  Delta(2)-isopentenylpyrophosphate tRNA-adenosine transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.


ensembl_gene_id: BDGL_001601
symbol: mutL
gene_biotype: protein_coding
description:
  Enzyme in methyl-directed mismatch repair, stimulates binding of Vsr and MutS to heteroduplex DNA; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.


ensembl_gene_id: BDGL_001621
symbol: coq7
gene_biotype: protein_coding
description:
  Putative ubiquinone biosynthesis protein; Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6- methoxy-1,4-benzoquinol during ubiquinone biosynthesis.


ensembl_gene_id: BDGL_001623
symbol: puuA
gene_biotype: protein_coding
description:
  Gamma-glutamylputrescine synthase; Putative glutamine synthetase with N-terminal domain and glutamine synthase/guanidino kinase catalytic domain.


ensembl_gene_id: BDGL_001625
symbol: kdpD
gene_biotype: protein_coding
description:
  Two-component system, OmpR family, sensor histidine kinase KdpD; Sensory kinase in two-component regulatory system wtih KdpE, regulates high-affinity potassium transport system.


ensembl_gene_id: BDGL_001626
symbol: kdpC
gene_biotype: protein_coding
description:
  Potassium-transporting ATPase C chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.


ensembl_gene_id: BDGL_001627
symbol: kdpB
gene_biotype: protein_coding
description:
  Potassium-transporting ATPase B chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.


ensembl_gene_id: BDGL_001628
symbol: kdpA
gene_biotype: protein_coding
description:
  Potassium-transporting ATPase A chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane.


ensembl_gene_id: BDGL_001630
symbol: folB
gene_biotype: protein_coding
description:
  Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.


ensembl_gene_id: BDGL_001635
symbol: ADY82221.1
gene_biotype: protein_coding
description:
  Putative 3-hydroxyacyl-CoA dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: BDGL_001639
symbol: hemK
gene_biotype: protein_coding
description:
  Methyl transferase; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.


ensembl_gene_id: BDGL_001640
symbol: prfA
gene_biotype: protein_coding
description:
  Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.


ensembl_gene_id: BDGL_001651
symbol: ADY82237.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.


ensembl_gene_id: BDGL_001652
symbol: ppsA
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.


ensembl_gene_id: BDGL_001658
symbol: cyoE
gene_biotype: protein_coding
description:
  Protoheme IX farnesyltransferase (heme O biosynthesis); Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.


ensembl_gene_id: BDGL_001660
symbol: rpsR
gene_biotype: protein_coding
description:
  30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.


ensembl_gene_id: BDGL_001662
symbol: dnaB
gene_biotype: protein_coding
description:
  Replicative DNA helicase;chromosome replication, chain elongation; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily.


ensembl_gene_id: BDGL_001663
symbol: alr
gene_biotype: protein_coding
description:
  Alanine racemase 1, biosynthetic; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.


ensembl_gene_id: BDGL_001670
symbol: gidA
gene_biotype: protein_coding
description:
  tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family.


ensembl_gene_id: BDGL_001672
symbol: prmA
gene_biotype: protein_coding
description:
  Methylation of 50S ribosomal subunit protein L11 (ribosomal protein L11 methyltransferase); Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family.


ensembl_gene_id: BDGL_001674
symbol: fis
gene_biotype: protein_coding
description:
  Fis family transcriptional regulator, factor for inversion stimulation protein; DNA-binding protein for site-specific recombination, transcription of rRNA and tRNA operons and DNA replication; Belongs to the transcriptional regulatory Fis family.


ensembl_gene_id: BDGL_001678
symbol: metN2
gene_biotype: protein_coding
description:
  D-and L-methionine transport protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.


ensembl_gene_id: BDGL_001680
symbol: gloB
gene_biotype: protein_coding
description:
  Putative hydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.


ensembl_gene_id: BDGL_001682
symbol: dctA-2
gene_biotype: protein_coding
description:
  C4-dicarboxylate transporter DctA; Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane. Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: BDGL_001712
symbol: blc
gene_biotype: protein_coding
description:
  Putative outer membrane lipoprotein (lipocalin); Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.


ensembl_gene_id: BDGL_001713
symbol: czcS
gene_biotype: protein_coding
description:
  Heavy metal sensor signal transduction histidine kinase; Member of a two-component regulatory system.


ensembl_gene_id: BDGL_001716
symbol: yedX
gene_biotype: protein_coding
description:
  Putative transthyretin-like protein; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.


ensembl_gene_id: BDGL_001727
symbol: kefBC
gene_biotype: protein_coding
description:
  Glutathione-regulated potassium-efflux system protein (K(+)/H(+) antiporter); Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.


ensembl_gene_id: BDGL_001728
symbol: gltS
gene_biotype: protein_coding
description:
  Sodium/glutamate symport carrier protein; Catalyzes the sodium-dependent transport of glutamate. Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.


ensembl_gene_id: BDGL_001737
symbol: gcp
gene_biotype: protein_coding
description:
  Putative O-sialoglycoprotein endopeptidase gcp; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.


ensembl_gene_id: BDGL_001740
symbol: ADY82326.1
gene_biotype: protein_coding
description:
  TPR domain protein; Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.


ensembl_gene_id: BDGL_001741
symbol: tkrA
gene_biotype: protein_coding
description:
  2-keto-D-gluconate reductase (2-ketoaldonate reductase); Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: BDGL_001744
symbol: purF
gene_biotype: protein_coding
description:
  Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.


ensembl_gene_id: BDGL_001746
symbol: pyrD
gene_biotype: protein_coding
description:
  Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.


ensembl_gene_id: BDGL_001748
symbol: ADY82334.1
gene_biotype: protein_coding
description:
  Putative general type II secretion pathway protein L (GspL family); Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.


ensembl_gene_id: BDGL_001750
symbol: gpsA
gene_biotype: protein_coding
description:
  Glycerol-3-phosphate dehydrogenase, biosynthetic; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.


ensembl_gene_id: BDGL_001753
symbol: rhlB
gene_biotype: protein_coding
description:
  ATP-dependent RNA helicase RhlB; DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. Belongs to the DEAD box helicase family. RhlB subfamily.


ensembl_gene_id: BDGL_001757
symbol: rpoH
gene_biotype: protein_coding
description:
  RNA polymerase factor sigma-32; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.


ensembl_gene_id: BDGL_001760
symbol: thiG
gene_biotype: protein_coding
description:
  Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.


ensembl_gene_id: BDGL_001764
symbol: rnz
gene_biotype: protein_coding
description:
  Ribonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family.


ensembl_gene_id: BDGL_001767
symbol: aroA
gene_biotype: protein_coding
description:
  Bifunctional protein aroA; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.


ensembl_gene_id: BDGL_001772
symbol: dctA-3
gene_biotype: protein_coding
description:
  C4-dicarboxylate transporter DctA; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: BDGL_001775
symbol: ppnK
gene_biotype: protein_coding
description:
  Putative inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.


ensembl_gene_id: BDGL_001776
symbol: mrcB
gene_biotype: protein_coding
description:
  Bifunctional protein mrcB; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).


ensembl_gene_id: BDGL_001795
symbol: argT
gene_biotype: protein_coding
description:
  ABC lysine-arginine-ornithine transporter, periplasmic ligand binding protein; Belongs to the bacterial solute-binding protein 3 family.


ensembl_gene_id: BDGL_001797
symbol: mdtA
gene_biotype: protein_coding
description:
  Putative RND family drug transporter; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: BDGL_001800
symbol: glyA
gene_biotype: protein_coding
description:
  Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.


ensembl_gene_id: BDGL_001807
symbol: queF
gene_biotype: protein_coding
description:
  7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).


ensembl_gene_id: BDGL_001809
symbol: rodA
gene_biotype: protein_coding
description:
  Rod shape-determining protein; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.


ensembl_gene_id: BDGL_001811
symbol: rlpA
gene_biotype: protein_coding
description:
  Putative lipoprotein precursor (RlpA-like); Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.


ensembl_gene_id: BDGL_001816
symbol: tsf
gene_biotype: protein_coding
description:
  Protein chain elongation factor EF-Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.


ensembl_gene_id: BDGL_001827
symbol: sahH
gene_biotype: protein_coding
description:
  S-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.


ensembl_gene_id: BDGL_001828
symbol: metF
gene_biotype: protein_coding
description:
  5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.


ensembl_gene_id: BDGL_001829
symbol: ADY82415.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.


ensembl_gene_id: BDGL_001832
symbol: cca
gene_biotype: protein_coding
description:
  tRNA nucleotidyl transferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.


ensembl_gene_id: BDGL_001835
symbol: sodB
gene_biotype: protein_coding
description:
  Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.


ensembl_gene_id: BDGL_001839
symbol: ubiA
gene_biotype: protein_coding
description:
  4-hydroxybenzoate octaprenyltransferase (4-HB polyprenyltransferase); Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.


ensembl_gene_id: BDGL_001840
symbol: ubiC
gene_biotype: protein_coding
description:
  Chorismate pyruvate lyase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family.


ensembl_gene_id: BDGL_001847
symbol: trpD
gene_biotype: protein_coding
description:
  Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).


ensembl_gene_id: BDGL_001858
symbol: hemE
gene_biotype: protein_coding
description:
  Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.


ensembl_gene_id: BDGL_001875
symbol: bauC
gene_biotype: protein_coding
description:
  Ferric siderophore ABC transporter, permease protein BauC; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: BDGL_001876
symbol: bauD
gene_biotype: protein_coding
description:
  Ferric siderophore ABC transporter, permease protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: BDGL_001877
symbol: basB-2
gene_biotype: protein_coding
description:
  Putative non-ribosomal peptide synthetase with condensation and peptidyl carrier protein domains (basB).


ensembl_gene_id: BDGL_001890
symbol: efp
gene_biotype: protein_coding
description:
  Elongation factor P; Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation; Belongs to the elongation factor P family.


ensembl_gene_id: BDGL_001902
symbol: surE
gene_biotype: protein_coding
description:
  Survival protein (acid phosphatase); Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.


ensembl_gene_id: BDGL_001908
symbol: trmU
gene_biotype: protein_coding
description:
  tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.


ensembl_gene_id: BDGL_001914
symbol: pstB
gene_biotype: protein_coding
description:
  High-affinity phosphate transport protein (ABC superfamily, ATP-bind); Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.


ensembl_gene_id: BDGL_001916
symbol: pstC
gene_biotype: protein_coding
description:
  High-affinity phosphate transport protein (ABC superfamily, membrane); Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: BDGL_001923
symbol: dat
gene_biotype: protein_coding
description:
  Diaminobutyrate--2-oxoglutarate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: BDGL_001929
symbol: hepA
gene_biotype: protein_coding
description:
  ATP-dependent helicase HepA; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily.


ensembl_gene_id: BDGL_001933
symbol: thiE
gene_biotype: protein_coding
description:
  Putative thiamin-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.


ensembl_gene_id: BDGL_001942
symbol: ydjN
gene_biotype: protein_coding
description:
  Putative transport protein; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: BDGL_001952
symbol: dacD
gene_biotype: protein_coding
description:
  Putative D-ala-D-ala-carboxypeptidase, penicillin-binding protein; Belongs to the peptidase S11 family.


ensembl_gene_id: BDGL_001955
symbol: phrB
gene_biotype: protein_coding
description:
  Deoxyribodipyrimidine photolyase (photoreactivation), FAD-binding protein; Belongs to the DNA photolyase family.


ensembl_gene_id: BDGL_001964
symbol: dusB
gene_biotype: protein_coding
description:
  tRNA-dihydrouridine synthase B; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily.


ensembl_gene_id: BDGL_001967
symbol: proB
gene_biotype: protein_coding
description:
  Gamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.


ensembl_gene_id: BDGL_001968
symbol: yhbZ
gene_biotype: protein_coding
description:
  GTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.


ensembl_gene_id: BDGL_001971
symbol: gap
gene_biotype: protein_coding
description:
  Glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.


ensembl_gene_id: BDGL_001973
symbol: blc-2
gene_biotype: protein_coding
description:
  Outer membrane lipoprotein Blc; Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.


ensembl_gene_id: BDGL_001974
symbol: uvrB
gene_biotype: protein_coding
description:
  Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate  [...]


ensembl_gene_id: BDGL_001983
symbol: ADY82569.1
gene_biotype: protein_coding
description:
  Probable NADP-dependent dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: BDGL_001985
symbol: pdxJ
gene_biotype: protein_coding
description:
  Pyridoxal phosphate biosynthetic protein PdxJ; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.


ensembl_gene_id: BDGL_001988
symbol: era
gene_biotype: protein_coding
description:
  GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.


ensembl_gene_id: BDGL_001989
symbol: rnc
gene_biotype: protein_coding
description:
  Ribonuclease III, ds RNA; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism (By similarity).


ensembl_gene_id: BDGL_001992
symbol: lepA
gene_biotype: protein_coding
description:
  GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.


ensembl_gene_id: BDGL_001995
symbol: nadB
gene_biotype: protein_coding
description:
  L-aspartate oxidase (quinolinate synthetase B); Catalyzes the oxidation of L-aspartate to iminoaspartate.


ensembl_gene_id: BDGL_001997
symbol: tmk
gene_biotype: protein_coding
description:
  Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.


ensembl_gene_id: BDGL_001998
symbol: mltG
gene_biotype: protein_coding
description:
  Putative periplasmic solute-binding protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family.


ensembl_gene_id: BDGL_002002
symbol: cysT
gene_biotype: protein_coding
description:
  Sulfate transport protein (ABC superfamily, membrane); Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: BDGL_002004
symbol: cysA
gene_biotype: protein_coding
description:
  Sulfate permease A protein, chromate resistance (ABC superfamily, ATP-bind); Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system.


ensembl_gene_id: BDGL_002007
symbol: dapD
gene_biotype: protein_coding
description:
  2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family.


ensembl_gene_id: BDGL_002008
symbol: queE
gene_biotype: protein_coding
description:
  Queuosine biosynthesis protein QueE; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.


ensembl_gene_id: BDGL_002009
symbol: queC
gene_biotype: protein_coding
description:
  Queuosine biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.


ensembl_gene_id: BDGL_002019
symbol: purL
gene_biotype: protein_coding
description:
  Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.


ensembl_gene_id: BDGL_002021
symbol: ruvA
gene_biotype: protein_coding
description:
  Holliday junction helicase subunit A; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.


ensembl_gene_id: BDGL_002022
symbol: ruvB
gene_biotype: protein_coding
description:
  Holliday junction DNA helicase B; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.


ensembl_gene_id: BDGL_002026
symbol: tolR
gene_biotype: protein_coding
description:
  Biopolymer transport protein TolR; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: BDGL_002029
symbol: tolB
gene_biotype: protein_coding
description:
  Tolerance to colicins E2, E, A, and K, required for OM integrity; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: BDGL_002030
symbol: pal
gene_biotype: protein_coding
description:
  Peptidoglycan-associated lipoprotein precursor; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: BDGL_002043
symbol: purN
gene_biotype: protein_coding
description:
  Phosphoribosylglycinamide formyltransferase 1; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.


ensembl_gene_id: BDGL_002048
symbol: lolD
gene_biotype: protein_coding
description:
  Transport protein of outer membrane lipoproteins (ABC superfamily, ATP-bind); Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.


ensembl_gene_id: BDGL_002053
symbol: serC
gene_biotype: protein_coding
description:
  3-phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.


ensembl_gene_id: BDGL_002058
symbol: gyrA
gene_biotype: protein_coding
description:
  DNA gyrase, subunit A, type II topoisomerase; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP- [...]


ensembl_gene_id: BDGL_002062
symbol: xerC
gene_biotype: protein_coding
description:
  Site-specific tyrosine recombinase; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.


ensembl_gene_id: BDGL_002065
symbol: dapF
gene_biotype: protein_coding
description:
  Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.


ensembl_gene_id: BDGL_002066
symbol: lysA
gene_biotype: protein_coding
description:
  Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.


ensembl_gene_id: BDGL_002070
symbol: radA
gene_biotype: protein_coding
description:
  DNA repair protein; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.


ensembl_gene_id: BDGL_002073
symbol: pdxB
gene_biotype: protein_coding
description:
  Erythronate-4-phosphate dehydrogenase; Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate.


ensembl_gene_id: BDGL_002075
symbol: fdhD
gene_biotype: protein_coding
description:
  Formate dehydrogenase formation protein; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.


ensembl_gene_id: BDGL_002076
symbol: ydeP
gene_biotype: protein_coding
description:
  Putative oxidoreductase molybdopterin; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: BDGL_002079
symbol: ADY82665.1
gene_biotype: protein_coding
description:
  Oxidoreductase, short chain dehydrogenase/reductase family; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: BDGL_002082
symbol: acrA
gene_biotype: protein_coding
description:
  Acriflavin resistance protein A precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: BDGL_002086
symbol: ADY82672.1
gene_biotype: protein_coding
description:
  Putative alpha-ribazole-5'-Pphosphatase (cobalamin biosynthesis) with phosphoglycerate mutase-like domain.


ensembl_gene_id: BDGL_002094
symbol: greB
gene_biotype: protein_coding
description:
  Transcription elongation factor GreB; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.


ensembl_gene_id: BDGL_002097
symbol: ttcA
gene_biotype: protein_coding
description:
  Predicted ATPase of the PP-loop superfamily implicated in cell cycle control; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.


ensembl_gene_id: BDGL_002104
symbol: dgkA
gene_biotype: protein_coding
description:
  Diacylglycerol kinase; Recycling of diacylglycerol produced during the turnover of membrane phospholipid.


ensembl_gene_id: BDGL_002105
symbol: groEL
gene_biotype: protein_coding
description:
  Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.


ensembl_gene_id: BDGL_002106
symbol: groES
gene_biotype: protein_coding
description:
  Chaperonin GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.


ensembl_gene_id: BDGL_002111
symbol: pckG
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.


ensembl_gene_id: BDGL_002113
symbol: glpK
gene_biotype: protein_coding
description:
  Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.


ensembl_gene_id: BDGL_002117
symbol: folD
gene_biotype: protein_coding
description:
  Bifunctional protein folD; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.


ensembl_gene_id: BDGL_002121
symbol: ADY82707.1
gene_biotype: protein_coding
description:
  7,8-dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.


ensembl_gene_id: BDGL_002122
symbol: ftsH
gene_biotype: protein_coding
description:
  Cell division protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family.  In the central section; belongs to the AAA ATPase family.


ensembl_gene_id: BDGL_002123
symbol: ftsJ
gene_biotype: protein_coding
description:
  Cell division protein; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.


ensembl_gene_id: BDGL_002130
symbol: greA
gene_biotype: protein_coding
description:
  Transcription elongation factor, cleaves 3' nucleotide of paused Mrna; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.


ensembl_gene_id: BDGL_002145
symbol: sucD
gene_biotype: protein_coding
description:
  succinyl-CoA synthetase alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.


ensembl_gene_id: BDGL_002146
symbol: sucC
gene_biotype: protein_coding
description:
  succinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.


ensembl_gene_id: BDGL_002148
symbol: sucB
gene_biotype: protein_coding
description:
  Dihydrolipoamide succinyltransferase, component of 2-oxoglutarate dehydrogenase complex (E2); E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).


ensembl_gene_id: BDGL_002153
symbol: sdhA
gene_biotype: protein_coding
description:
  Succinate dehydrogenase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.


ensembl_gene_id: BDGL_002154
symbol: sdhD
gene_biotype: protein_coding
description:
  Succinate dehydrogenase, hydrophobic subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH).


ensembl_gene_id: BDGL_002162
symbol: rpoD
gene_biotype: protein_coding
description:
  Sigma D (sigma 70) factor of RNA polymerase, major sigma factor during exponential growth; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.


ensembl_gene_id: BDGL_002164
symbol: lipB
gene_biotype: protein_coding
description:
  Lipoate-protein ligase B (lipoate biosynthesis protein B); Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.


ensembl_gene_id: BDGL_002174
symbol: trmL
gene_biotype: protein_coding
description:
  Putative tRNA/rRNA methyltransferase; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.


ensembl_gene_id: BDGL_002175
symbol: cysG
gene_biotype: protein_coding
description:
  Multifunctional protein; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family.  In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.


ensembl_gene_id: BDGL_002176
symbol: serS
gene_biotype: protein_coding
description:
  seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).


ensembl_gene_id: BDGL_002178
symbol: lolA
gene_biotype: protein_coding
description:
  Outer-membrane lipoproteins carrier protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).


ensembl_gene_id: BDGL_002180
symbol: rplU
gene_biotype: protein_coding
description:
  50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.


ensembl_gene_id: BDGL_002184
symbol: acrA-2
gene_biotype: protein_coding
description:
  Acriflavine resistance protein A precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: BDGL_002186
symbol: mexB-3
gene_biotype: protein_coding
description:
  Acridine efflux pump (RND family); Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: BDGL_002193
symbol: valS
gene_biotype: protein_coding
description:
  valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.


ensembl_gene_id: BDGL_002198
symbol: gltC-4
gene_biotype: protein_coding
description:
  LysR family transcriptional regulator, transcription activator of glutamate synthase operon; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: BDGL_002220
symbol: uppP3
gene_biotype: protein_coding
description:
  Undecaprenylpyrophosphate phosphatase (bacitracin resistance protein); Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.


ensembl_gene_id: BDGL_002231
symbol: ADY82817.1
gene_biotype: protein_coding
description:
  Putative Maf-like protein; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.


ensembl_gene_id: BDGL_002237
symbol: gatC
gene_biotype: protein_coding
description:
  aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family.


ensembl_gene_id: BDGL_002238
symbol: gatA-2
gene_biotype: protein_coding
description:
  aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln).


ensembl_gene_id: BDGL_002239
symbol: gatB
gene_biotype: protein_coding
description:
  aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily.


ensembl_gene_id: BDGL_002260
symbol: dapE
gene_biotype: protein_coding
description:
  Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily.


ensembl_gene_id: BDGL_002270
symbol: nolG
gene_biotype: protein_coding
description:
  Acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: BDGL_002271
symbol: proS
gene_biotype: protein_coding
description:
  prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...]


ensembl_gene_id: BDGL_002277
symbol: rutA
gene_biotype: protein_coding
description:
  Putative monooxygenase RutA; Catalyzes the pyrimidine ring opening between N-3 and C-4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate.


ensembl_gene_id: BDGL_002278
symbol: rutB
gene_biotype: protein_coding
description:
  Putative isochorismatase family protein RutB; In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2; Belongs to the isochorismatase family. RutB subfamily.


ensembl_gene_id: BDGL_002279
symbol: rutC
gene_biotype: protein_coding
description:
  Hypothetical protein; May reduce aminoacrylate peracid to aminoacrylate. Required to remove a toxic intermediate produce by the pyrimidine nitrogen degradation.


ensembl_gene_id: BDGL_002280
symbol: rutF
gene_biotype: protein_coding
description:
  Putative flavin:NADH reductase (oxydoreductase); Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway; Belongs to the non-flavoprotein flavin reductase family. RutF subfamily.


ensembl_gene_id: BDGL_002286
symbol: dsbC
gene_biotype: protein_coding
description:
  Putative thiol:disulfide interchange protein (DsbC-like); Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily.


ensembl_gene_id: BDGL_002292
symbol: mutM
gene_biotype: protein_coding
description:
  formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.


ensembl_gene_id: BDGL_002296
symbol: mscL
gene_biotype: protein_coding
description:
  Mechanosensitive channel; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.


ensembl_gene_id: BDGL_002299
symbol: rsmC
gene_biotype: protein_coding
description:
  Ribosomal RNA small subunit methyltransferase C; Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle; Belongs to the methyltransferase superfamily. RsmC family.


ensembl_gene_id: BDGL_002323
symbol: secA
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family.


ensembl_gene_id: BDGL_002329
symbol: accD
gene_biotype: protein_coding
description:
  acetylCoA carboxylase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.


ensembl_gene_id: BDGL_002330
symbol: trpA
gene_biotype: protein_coding
description:
  Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.


ensembl_gene_id: BDGL_002344
symbol: baeR
gene_biotype: protein_coding
description:
  Transcriptional regulator protein (OmpR family),response regulator in two-component regulatory system with BaeS, regulates RNA synthesis.


ensembl_gene_id: BDGL_002357
symbol: aspS
gene_biotype: protein_coding
description:
  aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.


ensembl_gene_id: BDGL_002369
symbol: ilvE
gene_biotype: protein_coding
description:
  Branched-chain amino acid transferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: BDGL_002370
symbol: glnE
gene_biotype: protein_coding
description:
  Glutamine synthetase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transducti [...]


ensembl_gene_id: BDGL_002372
symbol: queA
gene_biotype: protein_coding
description:
  S-adenosylmethionine:tRNA ribosyltransferase-isomerase (queuosine biosynthesis protein); Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).


ensembl_gene_id: BDGL_002373
symbol: tgt
gene_biotype: protein_coding
description:
  Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...]


ensembl_gene_id: BDGL_002374
symbol: yajC
gene_biotype: protein_coding
description:
  Putative preprotein translocase IISP family, membrane subunit; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.


ensembl_gene_id: BDGL_002375
symbol: secD
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.


ensembl_gene_id: BDGL_002376
symbol: secF
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.


ensembl_gene_id: BDGL_002377
symbol: dfp
gene_biotype: protein_coding
description:
  Bifunctional protein dfp; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.


ensembl_gene_id: BDGL_002381
symbol: ispZ
gene_biotype: protein_coding
description:
  Putative intracellular septation protein (IspZ); Involved in cell division; probably involved in intracellular septation; Belongs to the YciB family.


ensembl_gene_id: BDGL_002384
symbol: mnmC
gene_biotype: protein_coding
description:
  5-methylaminomethyl-2-thiouridine methyltransferase; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family.


ensembl_gene_id: BDGL_002402
symbol: grpE
gene_biotype: protein_coding
description:
  HSP 24 nucleotide exchange factor; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several roun [...]


ensembl_gene_id: BDGL_002403
symbol: dnaK
gene_biotype: protein_coding
description:
  Chaperone HSP70 in DNA biosynthesis/cell division; Acts as a chaperone; Belongs to the heat shock protein 70 family.


ensembl_gene_id: BDGL_002410
symbol: purK
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazole carboxylase ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).


ensembl_gene_id: BDGL_002411
symbol: purE
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazole carboxylase, mutase subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).


ensembl_gene_id: BDGL_002413
symbol: mpl
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso- diaminopimelate ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily.


ensembl_gene_id: BDGL_002420
symbol: guaD-2
gene_biotype: protein_coding
description:
  Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.


ensembl_gene_id: BDGL_002421
symbol: hpt
gene_biotype: protein_coding
description:
  Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.


ensembl_gene_id: BDGL_002423
symbol: dsbC-2
gene_biotype: protein_coding
description:
  Putative thiol:disulfide interchange protein; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily.


ensembl_gene_id: BDGL_002426
symbol: mnmE
gene_biotype: protein_coding
description:
  tRNA modification GTPase; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.


ensembl_gene_id: BDGL_002427
symbol: oxaA
gene_biotype: protein_coding
description:
  Putative inner membrane protein translocase component; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.


ensembl_gene_id: BDGL_002428
symbol: rnpA
gene_biotype: protein_coding
description:
  RNase P, protein C5 component, processes tRNA, 4.5S RNA; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.


ensembl_gene_id: BDGL_002430
symbol: dnaA-2
gene_biotype: protein_coding
description:
  DNA replication initiator protein, transcriptional regulator of replication and housekeeping genes; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.


ensembl_gene_id: BDGL_002433
symbol: recF
gene_biotype: protein_coding
description:
  DNA replication, recombinaison and repair protein; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.


ensembl_gene_id: BDGL_002434
symbol: gyrB
gene_biotype: protein_coding
description:
  DNA gyrase, subunit B (type II topoisomerase); A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP [...]


ensembl_gene_id: BDGL_002444
symbol: anmK
gene_biotype: protein_coding
description:
  anhydro-N-acetylmuramic acid kinase (AnhMurNAc kinase); Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family.


ensembl_gene_id: BDGL_002445
symbol: tyrS
gene_biotype: protein_coding
description:
  tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.


ensembl_gene_id: BDGL_002452
symbol: hflX
gene_biotype: protein_coding
description:
  GTP-binding protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.


ensembl_gene_id: BDGL_002456
symbol: apaH
gene_biotype: protein_coding
description:
  Bis(5'-nucleosyl)-tetraphosphatase; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family.


ensembl_gene_id: BDGL_002457
symbol: ksgA
gene_biotype: protein_coding
description:
  S-adenosylmethionine-6-N',N'-adenosyl (rRNA) dimethyltransferase, kasugamycin resistance; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.


ensembl_gene_id: BDGL_002459
symbol: pdxA
gene_biotype: protein_coding
description:
  4-hydroxythreonine-4-phosphate dehydrogenase (4-(phosphohydroxy)-L-threonine dehydrogenase); Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).


ensembl_gene_id: BDGL_002460
symbol: rplM
gene_biotype: protein_coding
description:
  50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.


ensembl_gene_id: BDGL_002485
symbol: mdh
gene_biotype: protein_coding
description:
  Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.


ensembl_gene_id: BDGL_002488
symbol: miaB
gene_biotype: protein_coding
description:
  Putative tRNA-i(6)A37 modification enzyme (MiaB); Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.


ensembl_gene_id: BDGL_002490
symbol: ybeY
gene_biotype: protein_coding
description:
  Hypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.


ensembl_gene_id: BDGL_002494
symbol: xpt
gene_biotype: protein_coding
description:
  Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.


ensembl_gene_id: BDGL_002504
symbol: rnr
gene_biotype: protein_coding
description:
  Exoribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.


ensembl_gene_id: BDGL_002516
symbol: rpoA
gene_biotype: protein_coding
description:
  RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: BDGL_002517
symbol: rpsD
gene_biotype: protein_coding
description:
  30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.


ensembl_gene_id: BDGL_002518
symbol: rpsK
gene_biotype: protein_coding
description:
  30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.


ensembl_gene_id: BDGL_002519
symbol: rpsM
gene_biotype: protein_coding
description:
  30S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family.


ensembl_gene_id: BDGL_002521
symbol: secY
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.


ensembl_gene_id: BDGL_002522
symbol: rplO
gene_biotype: protein_coding
description:
  50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.


ensembl_gene_id: BDGL_002524
symbol: rpsE
gene_biotype: protein_coding
description:
  30S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.


ensembl_gene_id: BDGL_002525
symbol: rplR
gene_biotype: protein_coding
description:
  50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.


ensembl_gene_id: BDGL_002526
symbol: rplF
gene_biotype: protein_coding
description:
  50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.


ensembl_gene_id: BDGL_002527
symbol: rpsH
gene_biotype: protein_coding
description:
  30S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.


ensembl_gene_id: BDGL_002528
symbol: rpsN
gene_biotype: protein_coding
description:
  30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family.


ensembl_gene_id: BDGL_002529
symbol: rplE
gene_biotype: protein_coding
description:
  50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.


ensembl_gene_id: BDGL_002530
symbol: rplX
gene_biotype: protein_coding
description:
  50S ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.


ensembl_gene_id: BDGL_002531
symbol: rplN
gene_biotype: protein_coding
description:
  50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.


ensembl_gene_id: BDGL_002532
symbol: rpsQ
gene_biotype: protein_coding
description:
  30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.


ensembl_gene_id: BDGL_002534
symbol: rplP
gene_biotype: protein_coding
description:
  50S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.


ensembl_gene_id: BDGL_002535
symbol: rpsC
gene_biotype: protein_coding
description:
  30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.


ensembl_gene_id: BDGL_002536
symbol: rplV
gene_biotype: protein_coding
description:
  50S ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.


ensembl_gene_id: BDGL_002537
symbol: rpsS
gene_biotype: protein_coding
description:
  30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.


ensembl_gene_id: BDGL_002538
symbol: rplB
gene_biotype: protein_coding
description:
  50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.


ensembl_gene_id: BDGL_002539
symbol: rplW
gene_biotype: protein_coding
description:
  50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.


ensembl_gene_id: BDGL_002541
symbol: rplC
gene_biotype: protein_coding
description:
  50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.


ensembl_gene_id: BDGL_002542
symbol: rpsJ
gene_biotype: protein_coding
description:
  30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.


ensembl_gene_id: BDGL_002549
symbol: engB
gene_biotype: protein_coding
description:
  GTP-binding protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.


ensembl_gene_id: BDGL_002551
symbol: glt-4
gene_biotype: protein_coding
description:
  Sodium:dicarboxylate symporter; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: BDGL_002556
symbol: recG
gene_biotype: protein_coding
description:
  ATP-dependent DNA helicase; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily.


ensembl_gene_id: BDGL_002569
symbol: dxs
gene_biotype: protein_coding
description:
  1-deoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.


ensembl_gene_id: BDGL_002570
symbol: ribA
gene_biotype: protein_coding
description:
  GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family.


ensembl_gene_id: BDGL_002571
symbol: hemF
gene_biotype: protein_coding
description:
  Coproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX.


ensembl_gene_id: BDGL_002572
symbol: aroE
gene_biotype: protein_coding
description:
  Dehydroshikimate reductase, NAD(P)-binding protein; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).


ensembl_gene_id: BDGL_002593
symbol: astE
gene_biotype: protein_coding
description:
  Succinylglutamate desuccinylase; Transforms N(2)-succinylglutamate into succinate and glutamate; Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.


ensembl_gene_id: BDGL_002594
symbol: astB
gene_biotype: protein_coding
description:
  Succinylarginine dihydrolase; Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)- succinylornithine, ammonia and CO(2).


ensembl_gene_id: BDGL_002595
symbol: astD
gene_biotype: protein_coding
description:
  Succinylglutamic semialdehyde dehydrogenase; Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.


ensembl_gene_id: BDGL_002597
symbol: astC-2
gene_biotype: protein_coding
description:
  Succinylornithine transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.


ensembl_gene_id: BDGL_002598
symbol: gdhA-2
gene_biotype: protein_coding
description:
  Glutamate dehydrogenase (NAD(P)+) oxidoreductase protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.


ensembl_gene_id: BDGL_002607
symbol: sodC
gene_biotype: protein_coding
description:
  Superoxide dismutase precursor (Cu-Zn); Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family.


ensembl_gene_id: BDGL_002617
symbol: serA
gene_biotype: protein_coding
description:
  D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: BDGL_002622
symbol: truB
gene_biotype: protein_coding
description:
  tRNA pseudouridine 55 synthase; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.


ensembl_gene_id: BDGL_002623
symbol: lifO
gene_biotype: protein_coding
description:
  Hypothetical protein; May be involved in the folding of the extracellular lipase during its passage through the periplasm; Belongs to the lipase chaperone family.


ensembl_gene_id: BDGL_002625
symbol: rplS
gene_biotype: protein_coding
description:
  50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.


ensembl_gene_id: BDGL_002626
symbol: trmD
gene_biotype: protein_coding
description:
  tRNA (guanine-1-)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.


ensembl_gene_id: BDGL_002627
symbol: rimM
gene_biotype: protein_coding
description:
  16S rRNA processing protein; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family.


ensembl_gene_id: BDGL_002636
symbol: ispH
gene_biotype: protein_coding
description:
  4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.


ensembl_gene_id: BDGL_002638
symbol: rpoZ
gene_biotype: protein_coding
description:
  RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.


ensembl_gene_id: BDGL_002655
symbol: aroB
gene_biotype: protein_coding
description:
  3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).


ensembl_gene_id: BDGL_002656
symbol: aroK
gene_biotype: protein_coding
description:
  Shikimate-kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.


ensembl_gene_id: BDGL_002665
symbol: mraY
gene_biotype: protein_coding
description:
  phospho-N-acetylmuramoyl-pentapeptide transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.


ensembl_gene_id: BDGL_002666
symbol: murF
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.


ensembl_gene_id: BDGL_002667
symbol: murE
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.


ensembl_gene_id: BDGL_002668
symbol: ftsI
gene_biotype: protein_coding
description:
  Septum formation, penicillin binding protein 3, peptidoglycan synthetase; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily.


ensembl_gene_id: BDGL_002669
symbol: ftsL
gene_biotype: protein_coding
description:
  Cell division protein (in growth at septum); Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.


ensembl_gene_id: BDGL_002670
symbol: mraW
gene_biotype: protein_coding
description:
  S-adenosylmethionine methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.


ensembl_gene_id: BDGL_002673
symbol: gltX
gene_biotype: protein_coding
description:
  glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.


ensembl_gene_id: BDGL_002679
symbol: czcA
gene_biotype: protein_coding
description:
  RND divalent metal cation efflux transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: BDGL_002690
symbol: ADY83276.1
gene_biotype: protein_coding
description:
  Oxidoreductase, short-chain dehydrogenase/reductase family protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: BDGL_002700
symbol: hisH
gene_biotype: protein_coding
description:
  Imidazole glycerol phosphate synthetase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.


ensembl_gene_id: BDGL_002710
symbol: hisF
gene_biotype: protein_coding
description:
  Imidazole glycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.


ensembl_gene_id: BDGL_002713
symbol: aqpZ
gene_biotype: protein_coding
description:
  Aquaporin Z; Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity; Belongs to the MIP/aquaporin (TC 1.A.8) family.


ensembl_gene_id: BDGL_002719
symbol: trkD
gene_biotype: protein_coding
description:
  Potassium transport system, low affinity (KUP family); Transport of potassium into the cell; Belongs to the HAK/KUP transporter (TC 2.A.72) family.


ensembl_gene_id: BDGL_002744
symbol: gabT
gene_biotype: protein_coding
description:
  4-aminobutyrate aminotransferase, PLP-dependent; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: BDGL_002751
symbol: ssb
gene_biotype: protein_coding
description:
  ssDNA-binding protein controls activity of RecBCD nuclease; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.


ensembl_gene_id: BDGL_002754
symbol: thiED-2
gene_biotype: protein_coding
description:
  Putative transcriptional activator (TenA family); Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family.


ensembl_gene_id: BDGL_002761
symbol: uvrA
gene_biotype: protein_coding
description:
  Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.


ensembl_gene_id: BDGL_002764
symbol: betT-3
gene_biotype: protein_coding
description:
  Putative high affinity choline transport protein (Bet-like); Belongs to the BCCT transporter (TC 2.A.15) family.


ensembl_gene_id: BDGL_002776
symbol: acsA2
gene_biotype: protein_coding
description:
  acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.


ensembl_gene_id: BDGL_002780
symbol: kdtA
gene_biotype: protein_coding
description:
  3-deoxy-D-manno-2-octulosonate transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.


ensembl_gene_id: BDGL_002783
symbol: prfB
gene_biotype: protein_coding
description:
  Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.


ensembl_gene_id: BDGL_002786
symbol: pdxH
gene_biotype: protein_coding
description:
  Pyridoxamine 5'-phosphate oxidase (acts also on pyridoxine phosphate and pyridoxine); Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).


ensembl_gene_id: BDGL_002787
symbol: glmM
gene_biotype: protein_coding
description:
  Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.


ensembl_gene_id: BDGL_002788
symbol: guaB
gene_biotype: protein_coding
description:
  IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.


ensembl_gene_id: BDGL_002794
symbol: aceE
gene_biotype: protein_coding
description:
  Pyruvate decarboxylase, E1 component of the pyruvate dehydrogenase complex; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


ensembl_gene_id: BDGL_002797
symbol: lpxC
gene_biotype: protein_coding
description:
  UDP-3-O-acyl-N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family.


ensembl_gene_id: BDGL_002798
symbol: ftsZ
gene_biotype: protein_coding
description:
  Cell division proteintubulin-like GTP-binding protein and GTPase; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.


ensembl_gene_id: BDGL_002799
symbol: ftsA
gene_biotype: protein_coding
description:
  Cell division protein; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.


ensembl_gene_id: BDGL_002800
symbol: ftsQ
gene_biotype: protein_coding
description:
  Cell division protein (in growth of wall at septum); Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.


ensembl_gene_id: BDGL_002803
symbol: murG
gene_biotype: protein_coding
description:
  Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.


ensembl_gene_id: BDGL_002809
symbol: pyrE
gene_biotype: protein_coding
description:
  Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).


ensembl_gene_id: BDGL_002821
symbol: ADY83407.1
gene_biotype: protein_coding
description:
  Putative transthyretin-like protein precursor; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.


ensembl_gene_id: BDGL_002827
symbol: parE
gene_biotype: protein_coding
description:
  Topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily.


ensembl_gene_id: BDGL_002836
symbol: dsbB
gene_biotype: protein_coding
description:
  Disulfide bond formation protein; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family.


ensembl_gene_id: BDGL_002837
symbol: gshA
gene_biotype: protein_coding
description:
  Gamma-glutamate-cysteine ligase; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.


ensembl_gene_id: BDGL_002851
symbol: psd
gene_biotype: protein_coding
description:
  Phosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).


ensembl_gene_id: BDGL_002853
symbol: pncB
gene_biotype: protein_coding
description:
  Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family.


ensembl_gene_id: BDGL_002854
symbol: dtd
gene_biotype: protein_coding
description:
  D-tyrosyl tRNA(tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family.


ensembl_gene_id: BDGL_002859
symbol: ribB-2
gene_biotype: protein_coding
description:
  3,4 dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.


ensembl_gene_id: BDGL_002860
symbol: ribH
gene_biotype: protein_coding
description:
  6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family.


ensembl_gene_id: BDGL_002861
symbol: nusB
gene_biotype: protein_coding
description:
  Transcription termination, L factor (N utilization substance protein B); Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.


ensembl_gene_id: BDGL_002862
symbol: thiL
gene_biotype: protein_coding
description:
  Thiamin-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.


ensembl_gene_id: BDGL_002863
symbol: pgpA
gene_biotype: protein_coding
description:
  Phosphatidylglycerophosphatase A; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).


ensembl_gene_id: BDGL_002864
symbol: glmU
gene_biotype: protein_coding
description:
  Bifunctional protein glmU; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.


ensembl_gene_id: BDGL_002871
symbol: hutG
gene_biotype: protein_coding
description:
  Formimidoylglutamase; Catalyzes the conversion of N-formimidoyl-L-glutamate to L- glutamate and formamide; Belongs to the arginase family.


ensembl_gene_id: BDGL_002875
symbol: hutU
gene_biotype: protein_coding
description:
  Urocanate hydratase (urocanase); Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate.


ensembl_gene_id: BDGL_002891
symbol: dapA-3
gene_biotype: protein_coding
description:
  Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).


ensembl_gene_id: BDGL_002915
symbol: dapB
gene_biotype: protein_coding
description:
  Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.


ensembl_gene_id: BDGL_002917
symbol: dnaJ
gene_biotype: protein_coding
description:
  Heat shock protein (HSP40), co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent  [...]


ensembl_gene_id: BDGL_002922
symbol: ppc
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family.


ensembl_gene_id: BDGL_002924
symbol: gltC-5
gene_biotype: protein_coding
description:
  Transcription activator of glutamate synthase operon GltC; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: BDGL_002928
symbol: fmt
gene_biotype: protein_coding
description:
  methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.


ensembl_gene_id: BDGL_002929
symbol: sun
gene_biotype: protein_coding
description:
  16S rRNA m5C967 SAM-dependent methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.


ensembl_gene_id: BDGL_002931
symbol: ADY83517.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.


ensembl_gene_id: BDGL_002937
symbol: lspA
gene_biotype: protein_coding
description:
  Prolipoprotein signal peptidase (signal peptidase II); This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.


ensembl_gene_id: BDGL_002938
symbol: ileS
gene_biotype: protein_coding
description:
  isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.


ensembl_gene_id: BDGL_002945
symbol: ssuD-6
gene_biotype: protein_coding
description:
  FMNH(2)-dependent alkanesulfonate monooxygenase; Catalyzes the desulfonation of aliphatic sulfonates. Belongs to the SsuD family.


ensembl_gene_id: BDGL_002948
symbol: argA
gene_biotype: protein_coding
description:
  N-alpha-acetylglutamate synthase (amino-acid acetyltransferase); Belongs to the acetyltransferase family. ArgA subfamily.


ensembl_gene_id: BDGL_002953
symbol: ubiG
gene_biotype: protein_coding
description:
  3-demethylubiquinone-9 3-methyltransferase and 2-octaprenyl-6-hydroxy phenol methylase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family.


ensembl_gene_id: BDGL_002959
symbol: rph
gene_biotype: protein_coding
description:
  Ribonuclease PH (RNase PH), tRNA nucleotidyltransferase; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.


ensembl_gene_id: BDGL_002963
symbol: nadC
gene_biotype: protein_coding
description:
  Nicotinate-nucleotide pyrophosphorylase (quinolinate phosphoribosyltransferase); Belongs to the NadC/ModD family.


ensembl_gene_id: BDGL_002965
symbol: mviN
gene_biotype: protein_coding
description:
  Probable lipid II flippase MurJ; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.


ensembl_gene_id: BDGL_002971
symbol: vipA
gene_biotype: protein_coding
description:
  Putative UDP-glucose/GDP-mannose dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.


ensembl_gene_id: BDGL_002991
symbol: lldP
gene_biotype: protein_coding
description:
  Lactate transporter, LctP family; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family.


ensembl_gene_id: BDGL_002993
symbol: lldD
gene_biotype: protein_coding
description:
  L-lactate dehydrogenase, FMN linked; Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain; Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.


ensembl_gene_id: BDGL_002994
symbol: dld
gene_biotype: protein_coding
description:
  D-lactate dehydrogenase, NADH independent, FAD-binding domain protein; Catalyzes the oxidation of D-lactate to pyruvate. Belongs to the quinone-dependent D-lactate dehydrogenase family.


ensembl_gene_id: BDGL_002998
symbol: prpB
gene_biotype: protein_coding
description:
  Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.


ensembl_gene_id: BDGL_003021
symbol: lrp-7
gene_biotype: protein_coding
description:
  Lrp/AsnC family transcriptional regulator, leucine-responsive regulatory protein; Transcriptional regulator for lrp regulon and high-affinity branched-chain amino acid transport system, mediator of leucine response (AsnC family).


ensembl_gene_id: BDGL_003023
symbol: dadX
gene_biotype: protein_coding
description:
  Alanine racemase 2, PLP-binding, catabolic; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.


ensembl_gene_id: BDGL_003038
symbol: solR
gene_biotype: protein_coding
description:
  Probable transcriptional activator of quorum sensing autoinducer synthesis transcription regulator protein.


ensembl_gene_id: BDGL_003047
symbol: bolA
gene_biotype: protein_coding
description:
  Putative activator of morphogenic pathway (BolA), important in general stress response; Belongs to the BolA/IbaG family.


ensembl_gene_id: BDGL_003056
symbol: ant
gene_biotype: protein_coding
description:
  Streptomycin 3''-adenylyltransferase (AADA-like); Mediates bacterial resistance to the antibiotics streptomycin and spectomycin.


ensembl_gene_id: BDGL_003068
symbol: znuC
gene_biotype: protein_coding
description:
  High affinity Zn transport protein (ABC superfamily); Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family.


ensembl_gene_id: BDGL_003072
symbol: atpB
gene_biotype: protein_coding
description:
  Membrane-bound ATP synthase, F0 sector, subunit a, important for FO assembly; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.


ensembl_gene_id: BDGL_003073
symbol: atpE
gene_biotype: protein_coding
description:
  Membrane-bound ATP synthase, F0 sector, subunit C; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.


ensembl_gene_id: BDGL_003074
symbol: atpF
gene_biotype: protein_coding
description:
  Membrane-bound ATP synthase, F0 sector, subunit B; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family.


ensembl_gene_id: BDGL_003075
symbol: atpH
gene_biotype: protein_coding
description:
  Membrane-bound ATP synthase, F1 sector, delta-subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family.


ensembl_gene_id: BDGL_003076
symbol: atpA
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family.


ensembl_gene_id: BDGL_003077
symbol: atpG
gene_biotype: protein_coding
description:
  Membrane-bound ATP synthase, F1 sector, gamma-subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.


ensembl_gene_id: BDGL_003078
symbol: atpD
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family.


ensembl_gene_id: BDGL_003079
symbol: atpC
gene_biotype: protein_coding
description:
  Membrane-bound ATP synthase, F1 sector, epsilon-subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane.


ensembl_gene_id: BDGL_003086
symbol: yrdC
gene_biotype: protein_coding
description:
  Putative SUA5/YciO/YrdC/YwlC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.


ensembl_gene_id: BDGL_003089
symbol: def
gene_biotype: protein_coding
description:
  Peptide deformylase 1 (N-formylmethionylaminoacyl-tRNA deformylase, binds Zn(II)); Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.


ensembl_gene_id: BDGL_003095
symbol: cysK
gene_biotype: protein_coding
description:
  Subunit of cysteine synthase A and O-acetylserine sulfhydrolase A, PLP-dependent enzyme; Belongs to the cysteine synthase/cystathionine beta- synthase family.


ensembl_gene_id: BDGL_003109
symbol: dinP
gene_biotype: protein_coding
description:
  DNA polymerase IV, devoid of proofreading, damage-inducible protein P; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.


ensembl_gene_id: BDGL_003111
symbol: farB
gene_biotype: protein_coding
description:
  MFS transporter, DHA2 family, multidrug resistance protein B; Belongs to the major facilitator superfamily.


ensembl_gene_id: BDGL_003117
symbol: parC
gene_biotype: protein_coding
description:
  DNA topoisomerase IV, subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.


ensembl_gene_id: BDGL_003121
symbol: ppa
gene_biotype: protein_coding
description:
  Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.


ensembl_gene_id: BDGL_003133
symbol: nrdR
gene_biotype: protein_coding
description:
  ATP-cone domain protein; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.


ensembl_gene_id: BDGL_003134
symbol: ribD
gene_biotype: protein_coding
description:
  Bifunctional protein ribD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.


ensembl_gene_id: BDGL_003140
symbol: pepA
gene_biotype: protein_coding
description:
  Aminopeptidase A; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.


ensembl_gene_id: BDGL_003143
symbol: gpmI
gene_biotype: protein_coding
description:
  Phosphoglycerate mutase III, cofactor independent; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.


ensembl_gene_id: BDGL_003148
symbol: pbpG
gene_biotype: protein_coding
description:
  D-alanyl-D-alanine endopeptidase, penicillin-binding protein 7 and penicillin-binding protein 8; Belongs to the peptidase S11 family.


ensembl_gene_id: BDGL_003149
symbol: thrC
gene_biotype: protein_coding
description:
  Threonine synthase, pyridoxal-5'-phosphate-dependent enzyme; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.


ensembl_gene_id: BDGL_003151
symbol: dsbC-3
gene_biotype: protein_coding
description:
  Thiol:disulfide interchange protein; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily.


ensembl_gene_id: BDGL_003156
symbol: murD
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.


ensembl_gene_id: BDGL_003157
symbol: ftsW
gene_biotype: protein_coding
description:
  Cell division protein, stabililzes FtsZ ring; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily.


ensembl_gene_id: BDGL_003158
symbol: gluQ
gene_biotype: protein_coding
description:
  Putative glutamyl t-RNA synthetase; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.


ensembl_gene_id: BDGL_003159
symbol: dksA
gene_biotype: protein_coding
description:
  DnaK suppressor protein; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.


ensembl_gene_id: BDGL_003160
symbol: icc
gene_biotype: protein_coding
description:
  Cyclic 3',5'-adenosine monophosphate phosphodiesterase (regulator of LacZ); Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.


ensembl_gene_id: BDGL_003162
symbol: thiC
gene_biotype: protein_coding
description:
  Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.


ensembl_gene_id: BDGL_003168
symbol: phoU
gene_biotype: protein_coding
description:
  Transcriptional repressor for high affinity phosphate uptake; Plays a role in the regulation of phosphate uptake.


ensembl_gene_id: BDGL_003169
symbol: ADY83755.1
gene_biotype: protein_coding
description:
  Protein-tyrosine-phosphatase; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.


ensembl_gene_id: BDGL_003173
symbol: hemC
gene_biotype: protein_coding
description:
  Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.


ensembl_gene_id: BDGL_003174
symbol: hemD
gene_biotype: protein_coding
description:
  uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.


ensembl_gene_id: BDGL_003184
symbol: trpE
gene_biotype: protein_coding
description:
  Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...]


ensembl_gene_id: BDGL_003186
symbol: secE
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61-gamma family.


ensembl_gene_id: BDGL_003187
symbol: nusG
gene_biotype: protein_coding
description:
  Transcription antitermination protein; Participates in transcription elongation, termination and antitermination.


ensembl_gene_id: BDGL_003188
symbol: rplK
gene_biotype: protein_coding
description:
  50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.


ensembl_gene_id: BDGL_003189
symbol: rplA
gene_biotype: protein_coding
description:
  50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.


ensembl_gene_id: BDGL_003190
symbol: rplJ
gene_biotype: protein_coding
description:
  50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.


ensembl_gene_id: BDGL_003191
symbol: rplL
gene_biotype: protein_coding
description:
  50S ribosomal protein; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family.


ensembl_gene_id: BDGL_003193
symbol: rpoB-2
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: BDGL_003194
symbol: rpoC
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase beta' chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: BDGL_003211
symbol: fadA-2
gene_biotype: protein_coding
description:
  3-ketoacyl-CoA thiolase; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.


ensembl_gene_id: BDGL_003212
symbol: fadB
gene_biotype: protein_coding
description:
  Fatty oxidation complex alpha subunit; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: BDGL_003218
symbol: uvrC
gene_biotype: protein_coding
description:
  Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.


ensembl_gene_id: BDGL_003220
symbol: pgsA
gene_biotype: protein_coding
description:
  CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: BDGL_003229
symbol: ADY83815.1
gene_biotype: protein_coding
description:
  Putative Holliday junction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family.


ensembl_gene_id: BDGL_003231
symbol: recN
gene_biotype: protein_coding
description:
  Protein used in recombination and DNA repair; May be involved in recombinational repair of damaged DNA.


ensembl_gene_id: BDGL_003233
symbol: ppnP
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.


ensembl_gene_id: BDGL_003234
symbol: rlmB
gene_biotype: protein_coding
description:
  Putative tRNA/rRNA methyltransferase; Specifically methylates the ribose of guanosine 2251 in 23S rRNA.


ensembl_gene_id: BDGL_003236
symbol: coaE
gene_biotype: protein_coding
description:
  Dephosphocoenzyme A kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.


ensembl_gene_id: BDGL_003237
symbol: pilD
gene_biotype: protein_coding
description:
  Type 4 prepilin-like proteins leader peptide processing enzyme; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.


ensembl_gene_id: BDGL_003241
symbol: tpiA
gene_biotype: protein_coding
description:
  Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.


ensembl_gene_id: BDGL_003242
symbol: secG
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.


ensembl_gene_id: BDGL_003243
symbol: rimP
gene_biotype: protein_coding
description:
  Hypothetical protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.


ensembl_gene_id: BDGL_003245
symbol: infB
gene_biotype: protein_coding
description:
  Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.


ensembl_gene_id: BDGL_003246
symbol: rbfA
gene_biotype: protein_coding
description:
  Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.


ensembl_gene_id: BDGL_003261
symbol: ubiE
gene_biotype: protein_coding
description:
  Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2).


ensembl_gene_id: BDGL_003265
symbol: recC
gene_biotype: protein_coding
description:
  Exonuclease V, gamma chain; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holo [...]


ensembl_gene_id: BDGL_003267
symbol: recB
gene_biotype: protein_coding
description:
  Exonuclease V, beta chain; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoe [...]


ensembl_gene_id: BDGL_003268
symbol: recD
gene_biotype: protein_coding
description:
  Exonuclease V, alpha subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Ho [...]


ensembl_gene_id: BDGL_003270
symbol: rpsO
gene_biotype: protein_coding
description:
  30S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.


ensembl_gene_id: BDGL_003271
symbol: pnp
gene_biotype: protein_coding
description:
  Polynucleotide phosphorylase/polyadenylase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.


ensembl_gene_id: BDGL_003276
symbol: hslO
gene_biotype: protein_coding
description:
  Heat shock protein HSP33; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress; Belongs to the HSP33 family.


ensembl_gene_id: BDGL_003278
symbol: priA
gene_biotype: protein_coding
description:
  Primosomal protein, ATP-dependent; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.


ensembl_gene_id: BDGL_003283
symbol: lnt
gene_biotype: protein_coding
description:
  Apolipoprotein N-acyltransferase, copper homeostasis protein; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily.


ensembl_gene_id: BDGL_003285
symbol: sirA
gene_biotype: protein_coding
description:
  Small ubiquitous protein required for normal growth; Belongs to the sulfur carrier protein TusA family.


ensembl_gene_id: BDGL_003287
symbol: etfD
gene_biotype: protein_coding
description:
  Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone.


ensembl_gene_id: BDGL_003291
symbol: hemH
gene_biotype: protein_coding
description:
  Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.


ensembl_gene_id: BDGL_003293
symbol: yacG
gene_biotype: protein_coding
description:
  Putative zinc-binding protein; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C- terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.


ensembl_gene_id: BDGL_003297
symbol: crcB
gene_biotype: protein_coding
description:
  High-copy crc-csp restores normal chromosome condensation in presence of camphor or MukB mutations; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.


ensembl_gene_id: BDGL_003306
symbol: ADY83892.1
gene_biotype: protein_coding
description:
  Putative oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.


ensembl_gene_id: BDGL_003310
symbol: rne
gene_biotype: protein_coding
description:
  Ribonuclease E (RNase E): endoribonuclease for rRNA processing and mRNA degradation; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily.


ensembl_gene_id: BDGL_003317
symbol: hcaR
gene_biotype: protein_coding
description:
  DNA-binding transcriptional activator of 3-phenylpropionic acid catabolism; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: BDGL_003319
symbol: katG
gene_biotype: protein_coding
description:
  Hydroperoxidase; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily.


ensembl_gene_id: BDGL_003321
symbol: nudH
gene_biotype: protein_coding
description:
  (di)nucleoside polyphosphate hydrolase (Ap5A pyrophosphatase); Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily.


ensembl_gene_id: BDGL_003327
symbol: leuC
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydratase (isomerase), subunit with LeuD; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.


ensembl_gene_id: BDGL_003328
symbol: leuD
gene_biotype: protein_coding
description:
  3-isopropylmalate isomerase (dehydratase), subunit with LeuC; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.


ensembl_gene_id: BDGL_003330
symbol: leuB
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.


ensembl_gene_id: BDGL_003333
symbol: infA
gene_biotype: protein_coding
description:
  Protein chain initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.


ensembl_gene_id: BDGL_003335
symbol: truA
gene_biotype: protein_coding
description:
  tRNA-pseudouridine synthase I; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.


ensembl_gene_id: BDGL_003339
symbol: asd
gene_biotype: protein_coding
description:
  Aspartate-semialdehyde dehydrogenase, NAD(P)-binding protein; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.


ensembl_gene_id: BDGL_003341
symbol: gltP
gene_biotype: protein_coding
description:
  Glutamate/aspartate:proton symporter; Catalyzes the proton-dependent transport of glutamate and aspartate; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. GltP subfamily.


ensembl_gene_id: BDGL_003347
symbol: ADY83933.1
gene_biotype: protein_coding
description:
  Putative Zn-dependent oxidoreductase; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.


ensembl_gene_id: BDGL_003350
symbol: topA
gene_biotype: protein_coding
description:
  DNA topoisomerase type I, omega protein; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, th [...]


ensembl_gene_id: BDGL_003358
symbol: ybaL
gene_biotype: protein_coding
description:
  Putative transport protein (CPA2 family); Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.


ensembl_gene_id: BDGL_003363
symbol: purU1
gene_biotype: protein_coding
description:
  Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).


ensembl_gene_id: BDGL_003367
symbol: msrA
gene_biotype: protein_coding
description:
  Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.


ensembl_gene_id: BDGL_003369
symbol: folA
gene_biotype: protein_coding
description:
  Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.


ensembl_gene_id: BDGL_003370
symbol: thyA
gene_biotype: protein_coding
description:
  thyA; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.


ensembl_gene_id: BDGL_003373
symbol: lgt
gene_biotype: protein_coding
description:
  Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.


ensembl_gene_id: BDGL_003377
symbol: tatC-2
gene_biotype: protein_coding
description:
  Sec-independent protein translocase protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.


ensembl_gene_id: BDGL_003378
symbol: tatB-2
gene_biotype: protein_coding
description:
  Sec-independent protein translocase protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.


ensembl_gene_id: BDGL_003379
symbol: tatA-2
gene_biotype: protein_coding
description:
  Sec-independent protein translocase protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.


ensembl_gene_id: BDGL_003381
symbol: ADY83967.1
gene_biotype: protein_coding
description:
  Putative protein controls HAP mutagenesis; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.


ensembl_gene_id: BDGL_003384
symbol: metX
gene_biotype: protein_coding
description:
  Homoserine O-acetyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.


ensembl_gene_id: BDGL_003385
symbol: leuA
gene_biotype: protein_coding
description:
  2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.


ensembl_gene_id: BDGL_003388
symbol: tig
gene_biotype: protein_coding
description:
  Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.


ensembl_gene_id: BDGL_003389
symbol: clpP
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.


ensembl_gene_id: BDGL_003390
symbol: clpX
gene_biotype: protein_coding
description:
  ATP-dependent protease ATP-binding subunit; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.


ensembl_gene_id: BDGL_003393
symbol: fumA
gene_biotype: protein_coding
description:
  Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.


ensembl_gene_id: BDGL_003394
symbol: pta
gene_biotype: protein_coding
description:
  Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.


ensembl_gene_id: BDGL_003395
symbol: ackA
gene_biotype: protein_coding
description:
  Acetate kinase (propionate kinase); Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.


ensembl_gene_id: BDGL_003397
symbol: edd
gene_biotype: protein_coding
description:
  Entner-Doudoroff pathway;edd; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family.


ensembl_gene_id: BDGL_003402
symbol: proA
gene_biotype: protein_coding
description:
  Gamma-glutamyl phosphate reductase (GPR); Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.


ensembl_gene_id: BDGL_003405
symbol: nagZ
gene_biotype: protein_coding
description:
  beta-N-acetyl-D-glucosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.


ensembl_gene_id: BDGL_003410
symbol: ndk
gene_biotype: protein_coding
description:
  Nucleoside diphosphate kinase (NDK); Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.


ensembl_gene_id: BDGL_003411
symbol: rlmN
gene_biotype: protein_coding
description:
  Putative Fe-S-cluster redox enzyme; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family.


ensembl_gene_id: BDGL_003414
symbol: ispG
gene_biotype: protein_coding
description:
  1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family.


ensembl_gene_id: BDGL_003418
symbol: ire-1
gene_biotype: protein_coding
description:
  Putative exported protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: BDGL_003419
symbol: engA
gene_biotype: protein_coding
description:
  GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.


ensembl_gene_id: BDGL_003423
symbol: acpP2
gene_biotype: protein_coding
description:
  Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.


ensembl_gene_id: BDGL_003430
symbol: ADY84016.1
gene_biotype: protein_coding
description:
  Flagellum-specific ATP synthase; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).


ensembl_gene_id: BDGL_003431
symbol: ADY84017.1
gene_biotype: protein_coding
description:
  Probable bifunctional protein : exporter and 1-acyl-sn-glycerol-3-phosphate acyltransferase precursor.


ensembl_gene_id: BDGL_003434
symbol: oxsM
gene_biotype: protein_coding
description:
  3-oxoacyl-(acyl carrier protein) synthase I; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: BDGL_003437
symbol: fabF
gene_biotype: protein_coding
description:
  3-oxoacyl-(acyl carrier protein) synthase II; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: BDGL_003440
symbol: secB
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.


ensembl_gene_id: BDGL_003441
symbol: grx
gene_biotype: protein_coding
description:
  Glutaredoxin; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.


ensembl_gene_id: BDGL_003443
symbol: engC
gene_biotype: protein_coding
description:
  GTPase EngC; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.


ensembl_gene_id: BDGL_003444
symbol: orn
gene_biotype: protein_coding
description:
  Oligoribonuclease; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family.


ensembl_gene_id: BDGL_003448
symbol: macB
gene_biotype: protein_coding
description:
  Macrolide transport protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.


ensembl_gene_id: BDGL_003449
symbol: macA
gene_biotype: protein_coding
description:
  Putative secretion protein (HlyD family); Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: BDGL_003451
symbol: rlpB
gene_biotype: protein_coding
description:
  Putative lipoprotein B precursor; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane; Belongs to the LptE lipoprotein family.


ensembl_gene_id: BDGL_003455
symbol: ilvC
gene_biotype: protein_coding
description:
  Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.


ensembl_gene_id: BDGL_003459
symbol: prfC
gene_biotype: protein_coding
description:
  Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.


ensembl_gene_id: BDGL_003469
symbol: dusA
gene_biotype: protein_coding
description:
  tRNA-dihydrouridine synthase A; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily.


ensembl_gene_id: BDGL_003475
symbol: pntB
gene_biotype: protein_coding
description:
  Pyridine nucleotide transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.


ensembl_gene_id: BDGL_003478
symbol: rsfS
gene_biotype: protein_coding
description:
  Hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.


ensembl_gene_id: BDGL_003485
symbol: rumA
gene_biotype: protein_coding
description:
  23S rRNA methyltransferase; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.


ensembl_gene_id: BDGL_003486
symbol: relA-2
gene_biotype: protein_coding
description:
  GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.


ensembl_gene_id: BDGL_003487
symbol: ADY84073.1
gene_biotype: protein_coding
description:
  Probable short-chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: BDGL_003490
symbol: pcnB
gene_biotype: protein_coding
description:
  poly(A) polymerase I (PAP); Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control. Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.


ensembl_gene_id: BDGL_003492
symbol: panB
gene_biotype: protein_coding
description:
  3-methyl-2-oxobutanoate hydroxymethyltransferase (ketopantoate hydroxymethyltransferase); Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.


ensembl_gene_id: BDGL_003493
symbol: panC
gene_biotype: protein_coding
description:
  Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.


ensembl_gene_id: BDGL_003498
symbol: thrS
gene_biotype: protein_coding
description:
  threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).


ensembl_gene_id: BDGL_003505
symbol: rplT
gene_biotype: protein_coding
description:
  rplT; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.


ensembl_gene_id: BDGL_003507
symbol: pheS
gene_biotype: protein_coding
description:
  phenylalanyl-tRNA synthetase, alpha-subunit; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.


ensembl_gene_id: BDGL_003508
symbol: pheT
gene_biotype: protein_coding
description:
  phenylalanyl-tRNA synthetase, beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.


ensembl_gene_id: BDGL_003509
symbol: himA
gene_biotype: protein_coding
description:
  Integration host factor (IHF), alpha subunit, DNA-binding protein, DNA replication; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.


ensembl_gene_id: BDGL_003512
symbol: rho
gene_biotype: protein_coding
description:
  Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.


ensembl_gene_id: BDGL_003515
symbol: accA
gene_biotype: protein_coding
description:
  Acetyl-coenzyme A carboxylase carboxyl transferase (alpha subunit); Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.


ensembl_gene_id: BDGL_003516
symbol: mesJ
gene_biotype: protein_coding
description:
  Cell cycle protein; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.


ensembl_gene_id: BDGL_003519
symbol: polA
gene_biotype: protein_coding
description:
  DNA polymerase I, 3'--> 5' polymerase, 5'--> 3' and 3'--> 5' exonuclease; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.


ensembl_gene_id: BDGL_003523
symbol: xcpR-2
gene_biotype: protein_coding
description:
  General secretion pathway protein E (type II traffic warden ATPase); Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.


ensembl_gene_id: BDGL_003531
symbol: rpoN
gene_biotype: protein_coding
description:
  RNA polymerase factor sigma-54; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.


ensembl_gene_id: BDGL_003534
symbol: murA
gene_biotype: protein_coding
description:
  UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.


ensembl_gene_id: BDGL_003535
symbol: hisG
gene_biotype: protein_coding
description:
  ATP-phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily.


ensembl_gene_id: BDGL_003536
symbol: hisD
gene_biotype: protein_coding
description:
  Histidinol dehydrogenase (HDH); Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.


ensembl_gene_id: BDGL_003537
symbol: hisC
gene_biotype: protein_coding
description:
  Histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.


ensembl_gene_id: BDGL_003561
symbol: ogt
gene_biotype: protein_coding
description:
  methylated-DNA--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.


ensembl_gene_id: BDGL_003562
symbol: argJ
gene_biotype: protein_coding
description:
  Bifunctional protein argJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.


ensembl_gene_id: BDGL_003563
symbol: nadA
gene_biotype: protein_coding
description:
  Quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate; Belongs to the quinolinate synthase A family. Type 1 subfamily.


