# geneInfo

ensembl_gene_id: Metbo_0001
symbol: ADZ08254.1
gene_biotype: protein_coding
description:
  KEGG: mth:MTH1537 adenylosuccinate lyase; TIGRFAM: Adenylosuccinate lyase; PFAM: Lyase 1, N-terminal; Adenylosuccinate lyase C-terminal metazoa/fungi; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.


ensembl_gene_id: Metbo_0003
symbol: ADZ08256.1
gene_biotype: protein_coding
description:
  UPF0107 protein; KEGG: mth:MTH1530 hypothetical protein; HAMAP: Uncharacterised protein family UPF0107; PFAM: Domain of unknown function DUF126; Belongs to the UPF0107 family.


ensembl_gene_id: Metbo_0009
symbol: ADZ08262.1
gene_biotype: protein_coding
description:
  TIGRFAM: ATPase, P-type, heavy metal translocating; ATPase, P type, cation/copper-transporter; Copper ion-binding; ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter; KEGG: mem:Memar_1873 heavy metal translocating P-type ATPase; PFAM: ATPase, P-type, ATPase-associated domain; Heavy metal transport/detoxification protein; Haloacid dehalogenase-like hydrolase.


ensembl_gene_id: Metbo_0011
symbol: truD
gene_biotype: protein_coding
description:
  tRNA pseudouridine synthase D; Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family.


ensembl_gene_id: Metbo_0012
symbol: ADZ08265.1
gene_biotype: protein_coding
description:
  KEGG: mmg:MTBMA_c01110 coenzyme F390 synthetase; TIGRFAM: Coenzyme F390 synthetase; PFAM: AMP-dependent synthetase/ligase.


ensembl_gene_id: Metbo_0014
symbol: dadD
gene_biotype: protein_coding
description:
  5-methylthioadenosine/S-adenosylhomocysteine deaminase; Catalyzes the deamination of three SAM-derived enzymatic products, namely 5'-deoxyadenosine, S-adenosyl-L-homocysteine, and 5'- methylthioadenosine, to produce the inosine analogs. Can also deaminate adenosine. The preferred substrate for this enzyme is 5'- deoxyadenosine, but all these substrates are efficiently deaminated. Likely functions in a S-adenosyl-L-methionine (SAM) recycling pathway from S-adenosyl-L-homocysteine (SAH) produced from SAM-dependent methylation reactions. May also be involved in the recycling of 5'- deoxya [...]


ensembl_gene_id: Metbo_0015
symbol: hisG
gene_biotype: protein_coding
description:
  ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily.


ensembl_gene_id: Metbo_0016
symbol: ADZ08269.1
gene_biotype: protein_coding
description:
  Ureidoglycolate lyase; KEGG: mfv:Mfer_0698 5-carboxymethyl-2-hydroxymuconatedelta-isomerase; PFAM: Fumarylacetoacetase, C-terminal-like.


ensembl_gene_id: Metbo_0017
symbol: leuS
gene_biotype: protein_coding
description:
  TIGRFAM: Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic; KEGG: mst:Msp_0171 leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: Metbo_0019
symbol: nadE
gene_biotype: protein_coding
description:
  NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.


ensembl_gene_id: Metbo_0020
symbol: ADZ08273.1
gene_biotype: protein_coding
description:
  Arsenite-activated ATPase ArsA; KEGG: mth:MTH1511 arsenical pump-driving ATPase; TIGRFAM: ATPase, anion-transporting.


ensembl_gene_id: Metbo_0022
symbol: ADZ08275.1
gene_biotype: protein_coding
description:
  PFAM: Protein of unknown function DUF2115; KEGG: mpl:Mpal_0722 hypothetical protein; Belongs to the UPF0305 family.


ensembl_gene_id: Metbo_0023
symbol: ADZ08276.1
gene_biotype: protein_coding
description:
  Precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; KEGG: mmg:MTBMA_c00990 precorrin-6Y methylase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase, core; PFAM: Tetrapyrrole methylase.


ensembl_gene_id: Metbo_0024
symbol: ADZ08277.1
gene_biotype: protein_coding
description:
  PFAM: GTPase of unknown function C-terminal; GTP-binding protein, HSR1-related; TGS; KEGG: mth:MTH1515 translation-associated GTPase.


ensembl_gene_id: Metbo_0030
symbol: ADZ08283.1
gene_biotype: protein_coding
description:
  KEGG: mbu:Mbur_0404 alkylhydroperoxidase-like protein; TIGRFAM: Alkylhydroperoxidase AhpD core; PFAM: Carboxymuconolactone decarboxylase.


ensembl_gene_id: Metbo_0031
symbol: ADZ08284.1
gene_biotype: protein_coding
description:
  PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: mmg:MTBMA_c11520 glyoxalase family protein.


ensembl_gene_id: Metbo_0035
symbol: ADZ08288.1
gene_biotype: protein_coding
description:
  PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: mfv:Mfer_0111 monooxygenase fad-binding protein.


ensembl_gene_id: Metbo_0036
symbol: sfsA
gene_biotype: protein_coding
description:
  TIGRFAM: Sugar fermentation stimulation protein; HAMAP: Sugar fermentation stimulation protein; KEGG: mmg:MTBMA_c01040 DNA-binding protein; PFAM: Sugar fermentation stimulation protein; Belongs to the SfsA family.


ensembl_gene_id: Metbo_0037
symbol: ADZ08290.1
gene_biotype: protein_coding
description:
  Methanogenesis marker 13 metalloprotein; KEGG: msi:Msm_1160 nitrogenase molybdenum-iron protein, NifD; TIGRFAM: Putative methanogenesis marker 13 metalloprotein; PFAM: Nitrogenase/oxidoreductase, component 1.


ensembl_gene_id: Metbo_0039
symbol: hisH
gene_biotype: protein_coding
description:
  Imidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.


ensembl_gene_id: Metbo_0040
symbol: ADZ08293.1
gene_biotype: protein_coding
description:
  PFAM: AIR synthase-related protein, C-terminal; AIR synthase-related protein; KEGG: mmg:MTBMA_c01080 HypE-related protein.


ensembl_gene_id: Metbo_0042
symbol: ADZ08295.1
gene_biotype: protein_coding
description:
  Phosphoesterase PA-phosphatase related protein; PFAM: Phosphatidic acid phosphatase type 2/haloperoxidase; KEGG: mpl:Mpal_0753 hypothetical protein.


ensembl_gene_id: Metbo_0043
symbol: ADZ08296.1
gene_biotype: protein_coding
description:
  L-aspartate oxidase; KEGG: mfv:Mfer_0085 thiol-driven fumarate reductase, flavoprotein subunit; PFAM: Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal; Fumarate reductase/succinate dehydrogenase flavoprotein, C-terminal.


ensembl_gene_id: Metbo_0044
symbol: sepS
gene_biotype: protein_coding
description:
  O-phosphoseryl-tRNA(Cys) synthetase; Catalyzes the attachment of O-phosphoserine (Sep) to tRNA(Cys).


ensembl_gene_id: Metbo_0045
symbol: ADZ08298.1
gene_biotype: protein_coding
description:
  Protein of unknown function DUF120; PFAM: Riboflavin kinase, CTP-dependent, archaeal; KEGG: mru:mru_2174 riboflavin kinase RibK.


ensembl_gene_id: Metbo_0046
symbol: ADZ08299.1
gene_biotype: protein_coding
description:
  3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.


ensembl_gene_id: Metbo_0047
symbol: ADZ08300.1
gene_biotype: protein_coding
description:
  PFAM: Cobyrinic acid a,c-diamide synthase; CobB/CobQ-like glutamine amidotransferase; KEGG: mmg:MTBMA_c00820 cobyrinic acid a,c-diamide synthase-related protein.


ensembl_gene_id: Metbo_0049
symbol: gatA
gene_biotype: protein_coding
description:
  Glutamyl-tRNA(Gln) amidotransferase subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln).


ensembl_gene_id: Metbo_0051
symbol: ala
gene_biotype: protein_coding
description:
  Alanine dehydrogenase; Catalyzes the NAD(+)-dependent oxidative deamination of L- alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate; Belongs to the ornithine cyclodeaminase/mu-crystallin family. Archaeal alanine dehydrogenase subfamily.


ensembl_gene_id: Metbo_0058
symbol: ADZ08311.1
gene_biotype: protein_coding
description:
  PFAM: Xylose isomerase, TIM barrel domain; KEGG: mmg:MTBMA_c00720 sugar phosphate isomerase/epimerase.


ensembl_gene_id: Metbo_0059
symbol: ADZ08312.1
gene_biotype: protein_coding
description:
  Transcriptional regulator, PadR-like family; PFAM: Transcription regulator PadR N-terminal-like; KEGG: mmg:MTBMA_c00710 transcriptional regulator.


ensembl_gene_id: Metbo_0060
symbol: ADZ08313.1
gene_biotype: protein_coding
description:
  SMART: ATPase, AAA+ type, core; TIGRFAM: Daunorubicin resistance ABC transporter ATP-binding subunit; KEGG: mth:MTH1487 ABC transporter (ATP-binding protein); PFAM: ABC transporter-like.


ensembl_gene_id: Metbo_0062
symbol: ADZ08315.1
gene_biotype: protein_coding
description:
  KEGG: mmg:MTBMA_c00680 hypothetical protein; PFAM: Pyrrolo-quinoline quinone repeat; SMART: Pyrrolo-quinoline quinone beta-propeller repeat.


ensembl_gene_id: Metbo_0063
symbol: albA
gene_biotype: protein_coding
description:
  DNA/RNA-binding protein Alba; Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes; Belongs to the histone-like Alba family.


ensembl_gene_id: Metbo_0064
symbol: ADZ08317.1
gene_biotype: protein_coding
description:
  KEGG: mth:MTH440 sensory transduction regulatory protein; PFAM: Signal transduction response regulator, receiver domain; PAS fold; SMART: Signal transduction response regulator, receiver domain; PAS.


ensembl_gene_id: Metbo_0065
symbol: ADZ08318.1
gene_biotype: protein_coding
description:
  KEGG: rci:RCIX2113 putative signal transduction protein; PFAM: Signal transduction response regulator, receiver domain; PAS fold; SMART: Signal transduction response regulator, receiver domain.


ensembl_gene_id: Metbo_0066
symbol: ADZ08319.1
gene_biotype: protein_coding
description:
  SMART: 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain; TIGRFAM: Isopropylmalate/citramalate/homocitrate synthase; KEGG: mth:MTH1481 2-isopropylmalate synthase; PFAM: Pyruvate carboxyltransferase; 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain; Belongs to the alpha-IPM synthase/homocitrate synthase family.


ensembl_gene_id: Metbo_0068
symbol: ADZ08321.1
gene_biotype: protein_coding
description:
  PHP domain protein; KEGG: mmg:MTBMA_c00610 phosphoesterase; PFAM: PHP, C-terminal; SMART: Polymerase/histidinol phosphatase, N-terminal.


ensembl_gene_id: Metbo_0069
symbol: ADZ08322.1
gene_biotype: protein_coding
description:
  PFAM: Protein of unknown function DUF1786, putative pyruvate format-lyase activating enzyme; KEGG: mmg:MTBMA_c00600 hypothetical protein.


ensembl_gene_id: Metbo_0070
symbol: trpB
gene_biotype: protein_coding
description:
  Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.


ensembl_gene_id: Metbo_0071
symbol: fae-hps
gene_biotype: protein_coding
description:
  Bifunctional enzyme fae/hps; Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin; In the N-terminal section; belongs to the formaldehyde- activating enzyme family.


ensembl_gene_id: Metbo_0072
symbol: ADZ08325.1
gene_biotype: protein_coding
description:
  PFAM: Cobalamin (vitamin B12) biosynthesis CbiM; KEGG: mru:mru_0539 cobalamin biosynthesis protein CbiM1.


ensembl_gene_id: Metbo_0074
symbol: ADZ08327.1
gene_biotype: protein_coding
description:
  Cobalt ABC transporter, inner membrane subunit CbiQ; KEGG: mru:mru_0541 cobalt ABC transporter permease protein CbiQ1; TIGRFAM: Cobalt ABC transporter CbiQ, permease subunit; PFAM: Cobalt transport protein.


ensembl_gene_id: Metbo_0077
symbol: hisB
gene_biotype: protein_coding
description:
  HAMAP: Imidazoleglycerol-phosphate dehydratase; KEGG: mru:mru_2139 bifunctional imidazoleglycerol-phosphate dehydratase HisB; PFAM: Imidazoleglycerol-phosphate dehydratase.


ensembl_gene_id: Metbo_0080
symbol: mtd
gene_biotype: protein_coding
description:
  F420-dependent methylenetetrahydromethanopterin dehydrogenase; Catalyzes the reversible reduction of methenyl-H(4)MPT(+) to methylene-H(4)MPT.


ensembl_gene_id: Metbo_0082
symbol: cbiA
gene_biotype: protein_coding
description:
  Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP- dependent amidation of the two carboxylate groups at positions a and c of Ni-sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source.


ensembl_gene_id: Metbo_0083
symbol: ADZ08336.1
gene_biotype: protein_coding
description:
  Manually curated; PFAM: Radical SAM; Helix-hairpin-helix motif; KEGG: mru:mru_2152 radical SAM domain-containing protein; SMART: Elongator protein 3/MiaB/NifB.


ensembl_gene_id: Metbo_0086
symbol: thrS
gene_biotype: protein_coding
description:
  TIGRFAM: Threonyl-tRNA synthetase, class IIa; KEGG: mth:MTH1455 threonyl-tRNA synthetase; PFAM: Threonyl-tRNA synthetase, editing domain, archaea; Aminoacyl-tRNA synthetase, class II (G/ H/ P/ S), conserved domain; Anticodon-binding; Belongs to the class-II aminoacyl-tRNA synthetase family.


ensembl_gene_id: Metbo_0087
symbol: ilvD
gene_biotype: protein_coding
description:
  PFAM: Dihydroxy-acid/6-phosphogluconate dehydratase; TIGRFAM: Dihydroxy-acid dehydratase; HAMAP: Dihydroxy-acid dehydratase; KEGG: mmg:MTBMA_c00370 dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.


ensembl_gene_id: Metbo_0088
symbol: ADZ08341.1
gene_biotype: protein_coding
description:
  KEGG: mth:MTH1448 signal peptidase; TIGRFAM: Peptidase S26B, eukaryotic signal peptidase; PFAM: Peptidase S24/S26A/S26B, conserved region.


ensembl_gene_id: Metbo_0089
symbol: argS
gene_biotype: protein_coding
description:
  KEGG: mth:MTH1447 arginyl-tRNA synthetase; TIGRFAM: Arginyl-tRNA synthetase, class Ic; HAMAP: Arginyl-tRNA synthetase, class Ic; Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: Metbo_0090
symbol: ADZ08343.1
gene_biotype: protein_coding
description:
  PFAM: Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain; Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding; TIGRFAM: Ornithine carbamoyltransferase; HAMAP: Ornithine carbamoyltransferase; KEGG: mfv:Mfer_0050 ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.


ensembl_gene_id: Metbo_0091
symbol: purD
gene_biotype: protein_coding
description:
  Phosphoribosylamine--glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; TIGRFAM: Phosphoribosylglycinamide synthetase; HAMAP: Phosphoribosylglycinamide synthetase; KEGG: mfv:Mfer_0051 phosphoribosylamine--glycine ligase; Belongs to the GARS family.


ensembl_gene_id: Metbo_0092
symbol: ADZ08345.1
gene_biotype: protein_coding
description:
  TIGRFAM: Acetolactate synthase, large subunit, biosynthetic; KEGG: mth:MTH1444 acetolactate synthase catalytic subunit; PFAM: Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain; Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, C-terminal TPP-binding.


ensembl_gene_id: Metbo_0093
symbol: ADZ08346.1
gene_biotype: protein_coding
description:
  KEGG: mfv:Mfer_0053 acetolactate synthase, small subunit; TIGRFAM: Acetolactate synthase, small subunit; PFAM: Acetolactate synthase, small subunit, C-terminal; Amino acid-binding ACT.


ensembl_gene_id: Metbo_0094
symbol: ilvC
gene_biotype: protein_coding
description:
  Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.


ensembl_gene_id: Metbo_0095
symbol: ADZ08348.1
gene_biotype: protein_coding
description:
  UPF0285 protein; KEGG: mmg:MTBMA_c00280 putative carbohydrate kinase of the FGGY family; TIGRFAM: Uncharacterised protein family UPF0285, methanogenesis; HAMAP: Uncharacterised protein family UPF0285, methanogenesis; Belongs to the UPF0285 family.


ensembl_gene_id: Metbo_0096
symbol: surE
gene_biotype: protein_coding
description:
  Multifunctional protein surE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.


ensembl_gene_id: Metbo_0098
symbol: ilvE
gene_biotype: protein_coding
description:
  Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: Metbo_0100
symbol: ADZ08353.1
gene_biotype: protein_coding
description:
  UPF0284 protein; TIGRFAM: Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, putative; HAMAP: Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, putative; KEGG: mmg:MTBMA_c00140 hypothetical protein; PFAM: Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like; Belongs to the UPF0284 family.


ensembl_gene_id: Metbo_0101
symbol: ADZ08354.1
gene_biotype: protein_coding
description:
  O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family.


ensembl_gene_id: Metbo_0102
symbol: ADZ08355.1
gene_biotype: protein_coding
description:
  Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.


ensembl_gene_id: Metbo_0103
symbol: rps15
gene_biotype: protein_coding
description:
  PFAM: Ribosomal protein S15; Ribosomal protein S13/S15, N-terminal; KEGG: mmg:MTBMA_c00110 30S ribosomal protein S15P.


ensembl_gene_id: Metbo_0104
symbol: ADZ08357.1
gene_biotype: protein_coding
description:
  PFAM: Phosphoesterase, RecJ-like; Phosphoesterase, DHHA1; KEGG: msi:Msm_1193 single-stranded DNA-specific exonuclease.


ensembl_gene_id: Metbo_0107
symbol: ADZ08360.1
gene_biotype: protein_coding
description:
  Helicase domain protein; KEGG: mth:MTH1415 Hef nuclease; PFAM: Helicase, C-terminal; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; ERCC4 domain; Helix-hairpin-helix motif; SMART: DEAD-like helicase, N-terminal; Helicase, C-terminal; ERCC4 domain; Helix-hairpin-helix DNA-binding motif, class 1.


ensembl_gene_id: Metbo_0108
symbol: ADZ08361.1
gene_biotype: protein_coding
description:
  tRNA (adenine-N(1)-)-methyltransferase; Manually curated; KEGG: mth:MTH1414 protein-L-isoaspartate methyltransferase-like protein; PFAM: Protein-L-isoaspartate(D-aspartate) O-methyltransferase.


ensembl_gene_id: Metbo_0109
symbol: pyrB
gene_biotype: protein_coding
description:
  PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding; Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain; TIGRFAM: Aspartate carbamoyltransferase, eukaryotic; HAMAP: Aspartate carbamoyltransferase, eukaryotic; KEGG: mmg:MTBMA_c00020 aspartate carbamoyltransferase.


ensembl_gene_id: Metbo_0111
symbol: cobD
gene_biotype: protein_coding
description:
  Cobalamin biosynthesis protein cbiB; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.


ensembl_gene_id: Metbo_0112
symbol: ADZ08365.1
gene_biotype: protein_coding
description:
  PFAM: Cobalamin (vitamin B12) biosynthesis CbiG, core; KEGG: mfv:Mfer_0934 cobalamin (vitamin b12) biosynthesis CbiG protein.


ensembl_gene_id: Metbo_0113
symbol: ADZ08366.1
gene_biotype: protein_coding
description:
  UPF0147 protein; KEGG: mmg:MTBMA_c17940 hypothetical protein; HAMAP: Uncharacterised protein family UPF0147; PFAM: Uncharacterised protein family UPF0147; Belongs to the UPF0147 family.


ensembl_gene_id: Metbo_0115
symbol: polB
gene_biotype: protein_coding
description:
  DNA-directed DNA polymerase; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase; Belongs to the DNA polymerase delta/II small subunit family.


ensembl_gene_id: Metbo_0117
symbol: ADZ08370.1
gene_biotype: protein_coding
description:
  precorrin-3B C17-methyltransferase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobJ/CibH, precorrin-3B C17-methyltransferase, core; KEGG: mfv:Mfer_1185 precorrin-3 methyltransferase; PFAM: Cysteine-rich small domain; Tetrapyrrole methylase.


ensembl_gene_id: Metbo_0118
symbol: dapF
gene_biotype: protein_coding
description:
  Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine.


ensembl_gene_id: Metbo_0119
symbol: lysA
gene_biotype: protein_coding
description:
  Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.


ensembl_gene_id: Metbo_0120
symbol: argD
gene_biotype: protein_coding
description:
  PFAM: Aminotransferase class-III; TIGRFAM: Acetylornithine/succinylornithine aminotransferase; HAMAP: Acetylornithine/succinyldiaminopimelate aminotransferase; KEGG: mfv:Mfer_0532 acetylornithine aminotransferase apoenzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.


ensembl_gene_id: Metbo_0121
symbol: ADZ08374.1
gene_biotype: protein_coding
description:
  PFAM: Peptidyl-prolyl cis-trans isomerase, cyclophilin-type; KEGG: rci:RCIX757 peptidyl-prolyl cis-trans isomerase B (cyclophilin type).


ensembl_gene_id: Metbo_0125
symbol: ADZ08378.1
gene_biotype: protein_coding
description:
  DNA-(apurinic or apyrimidinic site) lyase; PFAM: 8-oxoguanine DNA glycosylase, N-terminal; HhH-GPD domain; KEGG: msi:Msm_1365 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase; SMART: HhH-GPD domain.


ensembl_gene_id: Metbo_0126
symbol: ADZ08379.1
gene_biotype: protein_coding
description:
  Agmatinase; TIGRFAM: Putative agmatinase; KEGG: ara:Arad_7959 agmatinase; PFAM: Ureohydrolase; Belongs to the arginase family.


ensembl_gene_id: Metbo_0128
symbol: ADZ08381.1
gene_biotype: protein_coding
description:
  PFAM: Methylpurine-DNA glycosylase (MPG); TIGRFAM: Methylpurine-DNA glycosylase (MPG); HAMAP: Methylpurine-DNA glycosylase (MPG); KEGG: ccb:Clocel_1348 DNA-3-methyladenine glycosylase; Belongs to the DNA glycosylase MPG family.


ensembl_gene_id: Metbo_0131
symbol: hisF
gene_biotype: protein_coding
description:
  Imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.


ensembl_gene_id: Metbo_0132
symbol: ADZ08385.1
gene_biotype: protein_coding
description:
  PFAM: Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B; KEGG: mpl:Mpal_2574 extradiol ring-cleavage dioxygenase class III protein subunit B.


ensembl_gene_id: Metbo_0133
symbol: ADZ08386.1
gene_biotype: protein_coding
description:
  PFAM: Iron sulphur-containing domain, CDGSH-type; Ferredoxin soy-like; KEGG: mac:MA0986 hypothetical protein.


ensembl_gene_id: Metbo_0134
symbol: ADZ08387.1
gene_biotype: protein_coding
description:
  Type III restriction protein res subunit; KEGG: mmg:MTBMA_c17370 ATP-dependent helicase; PFAM: Restriction endonuclease, type I, R subunit/Type III, Res subunit; SMART: Helicase, ATP-dependent, c2 type; DEAD-like helicase, N-terminal.


ensembl_gene_id: Metbo_0135
symbol: ADZ08388.1
gene_biotype: protein_coding
description:
  Precorrin-2 C20-methyltransferase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobI/CbiL, precorrin-2 C20-methyltransferase, core; KEGG: mst:Msp_0038 CbiL; PFAM: Tetrapyrrole methylase.


ensembl_gene_id: Metbo_0136
symbol: ADZ08389.1
gene_biotype: protein_coding
description:
  Transcriptional regulator, ArsR family; KEGG: mpd:MCP_0329 putative transcriptional regulator; PFAM: 4-vinyl reductase, 4VR; HTH transcriptional regulator, ArsR; SMART: HTH transcriptional regulator, ArsR.


ensembl_gene_id: Metbo_0137
symbol: ADZ08390.1
gene_biotype: protein_coding
description:
  KEGG: mfv:Mfer_0426 flavodoxin/nitric oxide synthase; PFAM: Flavodoxin/nitric oxide synthase; Beta-lactamase-like; SMART: Beta-lactamase-like.


ensembl_gene_id: Metbo_0139
symbol: ADZ08392.1
gene_biotype: protein_coding
description:
  CoA-disulfide reductase; KEGG: mvn:Mevan_0572 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation.


ensembl_gene_id: Metbo_0140
symbol: cofH
gene_biotype: protein_coding
description:
  7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofH subunit; Catalyzes the radical-mediated synthesis of 5-amino-5-(4- hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil from 5-amino-6-(D- ribitylamino)uracil and L-tyrosine.


ensembl_gene_id: Metbo_0143
symbol: ADZ08395.1
gene_biotype: protein_coding
description:
  DsrE family protein; PFAM: Sulphur relay, DsrE/F-like protein; KEGG: mth:MTH1358 hypothetical protein.


ensembl_gene_id: Metbo_0146
symbol: ADZ08398.1
gene_biotype: protein_coding
description:
  Peptidase M50; KEGG: mmg:MTBMA_c17550 protease; PFAM: Peptidase M50; PDZ/DHR/GLGF; SMART: PDZ/DHR/GLGF.


ensembl_gene_id: Metbo_0147
symbol: ADZ08399.1
gene_biotype: protein_coding
description:
  TIGRFAM: Molybdenum cofactor synthesis; PFAM: MoeA, N-terminal and linker domain; Molybdopterin binding; MoeA, C-terminal, domain IV; KEGG: mmg:MTBMA_c17560 molybdenum cofactor biosynthesis protein; SMART: Molybdopterin binding.


ensembl_gene_id: Metbo_0149
symbol: ADZ08401.1
gene_biotype: protein_coding
description:
  Fe(3+)-transporting ATPase; PFAM: ABC transporter-like; KEGG: mth:MTH1370 ABC transporter ATP-binding protein; SMART: ATPase, AAA+ type, core.


ensembl_gene_id: Metbo_0153
symbol: purL
gene_biotype: protein_coding
description:
  Phosphoribosylformylglycinamidine synthase 2; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...]


ensembl_gene_id: Metbo_0154
symbol: ileS
gene_biotype: protein_coding
description:
  Isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.


ensembl_gene_id: Metbo_0155
symbol: mat
gene_biotype: protein_coding
description:
  S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP; Belongs to the AdoMet synthase 2 family.


ensembl_gene_id: Metbo_0158
symbol: ADZ08410.1
gene_biotype: protein_coding
description:
  Metallophosphoesterase; PFAM: Metallo-dependent phosphatase; KEGG: msi:Msm_1165 phosphohydrolase (metal-dependent).


ensembl_gene_id: Metbo_0160
symbol: ADZ08412.1
gene_biotype: protein_coding
description:
  KEGG: mmg:MTBMA_c17650 hypothetical protein; PFAM: PBS lyase HEAT-like repeat; SMART: PBS lyase HEAT-like repeat.


ensembl_gene_id: Metbo_0161
symbol: ADZ08413.1
gene_biotype: protein_coding
description:
  Archaeoflavoprotein, MJ0208 family; KEGG: mmg:MTBMA_c17660 conserved hypothetical protein containing a ferredoxin domain; TIGRFAM: Archaeoflavoprotein MJ0208; PFAM: Flavoprotein; 4Fe-4S binding domain.


ensembl_gene_id: Metbo_0162
symbol: glyA
gene_biotype: protein_coding
description:
  Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydromethanopterin (H4MPT) serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro- aldol mechanism; Belongs to the SHMT family.


ensembl_gene_id: Metbo_0164
symbol: ADZ08416.1
gene_biotype: protein_coding
description:
  4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).


ensembl_gene_id: Metbo_0166
symbol: radA
gene_biotype: protein_coding
description:
  DNA repair and recombination protein radA; Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.


ensembl_gene_id: Metbo_0167
symbol: ADZ08419.1
gene_biotype: protein_coding
description:
  Replication factor-A domain protein; PFAM: Replication factor A, C-terminal; Nucleic acid binding, OB-fold, tRNA/helicase-type; KEGG: mmg:MTBMA_c17710 replication factor A.


ensembl_gene_id: Metbo_0168
symbol: ADZ08420.1
gene_biotype: protein_coding
description:
  Regulatory protein MarR; KEGG: hor:Hore_04050 transcriptional regulator, MarR family; PFAM: HTH transcriptional regulator, MarR; SMART: HTH transcriptional regulator, MarR.


ensembl_gene_id: Metbo_0169
symbol: leuC
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.


ensembl_gene_id: Metbo_0170
symbol: leuD
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily.


ensembl_gene_id: Metbo_0171
symbol: ADZ08423.1
gene_biotype: protein_coding
description:
  KEGG: mru:mru_0103 3-isopropylmalate dehydrogenase LeuB; PFAM: Isocitrate/isopropylmalate dehydrogenase.


ensembl_gene_id: Metbo_0172
symbol: ADZ08424.1
gene_biotype: protein_coding
description:
  Cysteine desulfurase; KEGG: mmg:MTBMA_c17750 cystein desulfurase; PFAM: Aminotransferase, class V/Cysteine desulfurase.


ensembl_gene_id: Metbo_0173
symbol: ribH
gene_biotype: protein_coding
description:
  6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.


ensembl_gene_id: Metbo_0174
symbol: ADZ08426.1
gene_biotype: protein_coding
description:
  PFAM: Major facilitator superfamily MFS-1; KEGG: mfe:Mefer_0871 major facilitator superfamily MFS_1.


ensembl_gene_id: Metbo_0175
symbol: ADZ08427.1
gene_biotype: protein_coding
description:
  Methanogenesis marker protein 11; KEGG: msi:Msm_1295 DNA-binding protein; TIGRFAM: Putative methanogenesis marker protein 11; PFAM: Domain of unknown function DUF1743.


ensembl_gene_id: Metbo_0177
symbol: purE
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).


ensembl_gene_id: Metbo_0178
symbol: ADZ08430.1
gene_biotype: protein_coding
description:
  UbiD family decarboxylase; KEGG: mst:Msp_1479 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; TIGRFAM: Carboxylyase-related; PFAM: Carboxylyase-related.


ensembl_gene_id: Metbo_0180
symbol: thiL
gene_biotype: protein_coding
description:
  Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.


ensembl_gene_id: Metbo_0181
symbol: cbiX
gene_biotype: protein_coding
description:
  Sirohydrochlorin cobaltochelatase; Catalyzes the insertion of Co(2+) into sirohydrochlorin as part of the anaerobic pathway to cobalamin biosynthesis. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the insertion of Ni(2+) into sirohydrochlorin to yield Ni- sirohydrochlorin.


ensembl_gene_id: Metbo_0182
symbol: ADZ08434.1
gene_biotype: protein_coding
description:
  PFAM: Domain of unknown function DUF35, OB-fold, C-terminal; KEGG: mmg:MTBMA_c17840 nucleic acid-binding protein.


ensembl_gene_id: Metbo_0185
symbol: ADZ08437.1
gene_biotype: protein_coding
description:
  Transcriptional regulator, AsnC family; KEGG: mst:Msp_1556 transcriptional regulator; PFAM: Transcription regulator AsnC-type, C-terminal; SMART: Transcription regulator AsnC-type.


ensembl_gene_id: Metbo_0186
symbol: ADZ08438.1
gene_biotype: protein_coding
description:
  MgtE intracellular region; KEGG: mst:Msp_1555 hypothetical protein; PFAM: Magnesium transporter, MgtE intracellular domain; Cystathionine beta-synthase, core; SMART: Magnesium transporter, MgtE intracellular domain; Cystathionine beta-synthase, core.


ensembl_gene_id: Metbo_0188
symbol: ADZ08440.1
gene_biotype: protein_coding
description:
  Methylase; KEGG: mmg:MTBMA_c17150 methyltransferase; TIGRFAM: Putative methylase; PFAM: Methyltransferase small.


ensembl_gene_id: Metbo_0191
symbol: rsmA
gene_biotype: protein_coding
description:
  Ribosomal RNA small subunit methyltransferase A; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.


ensembl_gene_id: Metbo_0194
symbol: rpl21e
gene_biotype: protein_coding
description:
  KEGG: mmg:MTBMA_c17090 50S ribosomal protein L21e; HAMAP: Ribosomal protein L21e, archaeal; PFAM: Ribosomal protein L21e; Belongs to the eukaryotic ribosomal protein eL21 family.


ensembl_gene_id: Metbo_0195
symbol: pus10
gene_biotype: protein_coding
description:
  Conserved hypothetical protein CHP01213; Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.


ensembl_gene_id: Metbo_0196
symbol: srp54
gene_biotype: protein_coding
description:
  Signal recognition 54 kDa protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.


ensembl_gene_id: Metbo_0197
symbol: hpt
gene_biotype: protein_coding
description:
  Phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily.


ensembl_gene_id: Metbo_0198
symbol: ADZ08450.1
gene_biotype: protein_coding
description:
  Universal diphthamide biosynthesis domain-containing protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family.


ensembl_gene_id: Metbo_0199
symbol: csl4
gene_biotype: protein_coding
description:
  RNA-binding domain, S1; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs.


ensembl_gene_id: Metbo_0200
symbol: ADZ08452.1
gene_biotype: protein_coding
description:
  PFAM: DNA-directed RNA polymerase, dimerisation; KEGG: mth:MTH1317 DNA-dependent RNA polymerase, subunit L.


ensembl_gene_id: Metbo_0201
symbol: ADZ08453.1
gene_biotype: protein_coding
description:
  UPF0215 protein; Manually curated; HAMAP: Protein of unknown function DUF99; KEGG: mmg:MTBMA_c17020 hypothetical protein; PFAM: Protein of unknown function DUF99; Belongs to the UPF0215 family.


ensembl_gene_id: Metbo_0203
symbol: ADZ08455.1
gene_biotype: protein_coding
description:
  Transcription termination factor Tfs; TIGRFAM: DNA-directed RNA polymerase, subunit M, archaeal; PFAM: Zinc finger, TFIIS-type; DNA-directed RNA polymerase, M/15kDa subunit; KEGG: mst:Msp_1533 RpoM1; SMART: Zinc finger, TFIIS-type; DNA-directed RNA polymerase, M/15kDa subunit; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.


ensembl_gene_id: Metbo_0205
symbol: pcn
gene_biotype: protein_coding
description:
  DNA polymerase sliding clamp; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.


ensembl_gene_id: Metbo_0208
symbol: rps27e
gene_biotype: protein_coding
description:
  KEGG: mmg:MTBMA_c16950 30S ribosomal protein S27e; HAMAP: Ribosomal protein S27e, archaea; PFAM: Ribosomal protein S27e.


ensembl_gene_id: Metbo_0209
symbol: eif2a
gene_biotype: protein_coding
description:
  Translation initiation factor 2 subunit alpha; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-alpha family.


ensembl_gene_id: Metbo_0210
symbol: nop10
gene_biotype: protein_coding
description:
  Ribosome biogenesis protein Nop10; Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA.


ensembl_gene_id: Metbo_0212
symbol: ADZ08464.1
gene_biotype: protein_coding
description:
  KEGG: mmg:MTBMA_c16910 hypothetical protein; TIGRFAM: Conserved hypothetical protein CHP00375; PFAM: PHP, C-terminal.


ensembl_gene_id: Metbo_0218
symbol: ADZ08470.1
gene_biotype: protein_coding
description:
  TIGRFAM: Coenzyme F420 hydrogenase, subunit alpha; KEGG: mth:MTH1300 coenzyme F420-reducing hydrogenase, alpha subunit; PFAM: Nickel-dependent hydrogenase, large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.


ensembl_gene_id: Metbo_0219
symbol: ADZ08471.1
gene_biotype: protein_coding
description:
  KEGG: mmg:MTBMA_c16850 F420-reducing hydrogenase, subunit delta; TIGRFAM: Peptidase A31, coenzyme F420-reducing hydrogenase delta subunit; Peptidase A31, hydrogen uptake protein; PFAM: Peptidase A31, hydrogen uptake protein.


ensembl_gene_id: Metbo_0220
symbol: ADZ08472.1
gene_biotype: protein_coding
description:
  TIGRFAM: Coenzyme F420 hydrogenase, subunit gamma; KEGG: mmg:MTBMA_c16840 F420-reducing hydrogenase, subunit gamma; PFAM: NADH:ubiquinone oxidoreductase-like, 20kDa subunit; 4Fe-4S binding domain.


ensembl_gene_id: Metbo_0221
symbol: ADZ08473.1
gene_biotype: protein_coding
description:
  TIGRFAM: Coenzyme F420 hydrogenase, subunit beta; KEGG: mmg:MTBMA_c16830 F420-reducing hydrogenase, subunit beta; PFAM: Coenzyme F420 hydrogenase/dehydrogenase beta subunit, C-terminal; Coenzyme F420 hydrogenase/dehydrogenase beta subunit, N-terminal.


ensembl_gene_id: Metbo_0222
symbol: map
gene_biotype: protein_coding
description:
  Methionine aminopeptidase, type II; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val); Belongs to the peptidase M24A family. Methionine aminopeptidase archaeal type 2 subfamily.


ensembl_gene_id: Metbo_0228
symbol: dnaJ
gene_biotype: protein_coding
description:
  Chaperone protein dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]


ensembl_gene_id: Metbo_0230
symbol: grpE
gene_biotype: protein_coding
description:
  Protein grpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]


ensembl_gene_id: Metbo_0231
symbol: ADZ08483.1
gene_biotype: protein_coding
description:
  Transcriptional regulator, ArsR family; KEGG: mst:Msp_1519 transcriptional regulator; PFAM: HTH transcriptional regulator, ArsR; SMART: HTH transcriptional regulator, ArsR.


ensembl_gene_id: Metbo_0232
symbol: ADZ08484.1
gene_biotype: protein_coding
description:
  Acylphosphatase; TIGRFAM: Carbamoyltransferase, HypF-type; HAMAP: Acylphosphatase; KEGG: mmg:MTBMA_c16720 hydrogenase maturation factor HypF; PFAM: Sua5/YciO/YrdC, N-terminal; Acylphosphatase-like; Zinc finger, HypF-type.


ensembl_gene_id: Metbo_0233
symbol: ADZ08485.1
gene_biotype: protein_coding
description:
  PFAM: 4Fe-4S binding domain; KEGG: amt:Amet_1416 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein.


ensembl_gene_id: Metbo_0234
symbol: ADZ08486.1
gene_biotype: protein_coding
description:
  ThiJ/PfpI domain-containing protein; PFAM: ThiJ/PfpI; KEGG: ppm:PPSC2_c3928 intracellular protease, ThiJ/PfpI family.


ensembl_gene_id: Metbo_0236
symbol: ADZ08488.1
gene_biotype: protein_coding
description:
  KEGG: mmg:MTBMA_c15860 DNA polymerase; PFAM: DNA-directed DNA polymerase, family B, conserved region; DNA-directed DNA polymerase, family B, exonuclease domain; SMART: DNA-directed DNA polymerase, family B.


ensembl_gene_id: Metbo_0240
symbol: ADZ08492.1
gene_biotype: protein_coding
description:
  KEGG: dth:DICTH_0191 pyrroline-5-carboxylate reductase; PFAM: NADP oxidoreductase, coenzyme F420-dependent.


ensembl_gene_id: Metbo_0242
symbol: ADZ08494.1
gene_biotype: protein_coding
description:
  Beta-lactamase domain protein; KEGG: mth:MTH1267 hypothetical protein; PFAM: Beta-lactamase-like; SMART: Beta-lactamase-like.


ensembl_gene_id: Metbo_0243
symbol: ADZ08495.1
gene_biotype: protein_coding
description:
  TrkA-N domain protein; PFAM: Regulator of K+ conductance, N-terminal; Regulator of K+ conductance, C-terminal; KEGG: mth:MTH1265 trk system potassium uptake protein TrkA.


ensembl_gene_id: Metbo_0244
symbol: ADZ08496.1
gene_biotype: protein_coding
description:
  KEGG: mmg:MTBMA_c16510 potassium uptake protein TrkH; TIGRFAM: Potassium uptake protein TrkH; PFAM: Cation transporter.


ensembl_gene_id: Metbo_0245
symbol: ADZ08497.1
gene_biotype: protein_coding
description:
  Band 7 protein; KEGG: mth:MTH1780 stomatin-like protein; PFAM: Band 7 protein; SMART: Band 7 protein.


ensembl_gene_id: Metbo_0246
symbol: ADZ08498.1
gene_biotype: protein_coding
description:
  Pseudomurein-binding repeat-containing protein; PFAM: Pseudomurein-binding repeat; Peptidase C39, bacteriocin processing.


ensembl_gene_id: Metbo_0247
symbol: ADZ08499.1
gene_biotype: protein_coding
description:
  UPF0145 protein ybjQ; KEGG: msi:Msm_0418 hypothetical protein; HAMAP: Uncharacterised protein family UPF0145; PFAM: Uncharacterised protein family UPF0145; Belongs to the UPF0145 family.


ensembl_gene_id: Metbo_0249
symbol: ADZ08501.1
gene_biotype: protein_coding
description:
  KEGG: mmg:MTBMA_c12790 glycosyltransferase; TIGRFAM: Conserved hypothetical protein CHP00661; PFAM: Glycosyl transferase, family 2.


ensembl_gene_id: Metbo_0250
symbol: ADZ08502.1
gene_biotype: protein_coding
description:
  Phosphodiesterase, MJ0936 family; KEGG: mmg:MTBMA_c16490 phosphodiesterase; TIGRFAM: Phosphodiesterase MJ0936; PFAM: Metallo-dependent phosphatase.


ensembl_gene_id: Metbo_0252
symbol: ftr
gene_biotype: protein_coding
description:
  Formylmethanofuran/tetrahydromethanopterin N-formyltransferase; Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) so as to produce 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) and methanofuran (MFR); Belongs to the FTR family.


ensembl_gene_id: Metbo_0253
symbol: ADZ08505.1
gene_biotype: protein_coding
description:
  TrkA-N domain protein; PFAM: Regulator of K+ conductance, N-terminal; Ion transport 2; 3H domain; KEGG: mmg:MTBMA_c16450 transporter protein.


ensembl_gene_id: Metbo_0254
symbol: nnrE
gene_biotype: protein_coding
description:
  YjeF-related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.  Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epi [...]


ensembl_gene_id: Metbo_0256
symbol: argG
gene_biotype: protein_coding
description:
  PFAM: Argininosuccinate synthase; TIGRFAM: Argininosuccinate synthase; HAMAP: Argininosuccinate synthase; KEGG: mth:MTH1254 argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.


ensembl_gene_id: Metbo_0260
symbol: ADZ08512.1
gene_biotype: protein_coding
description:
  PFAM: Multiple resistance and pH regulation protein F; KEGG: mth:MTH1250 putative monovalent cation/H+ antiporter subunit F.


ensembl_gene_id: Metbo_0263
symbol: ADZ08515.1
gene_biotype: protein_coding
description:
  PFAM: NADH-ubiquinone oxidoreductase chain 4L/K; KEGG: mth:MTH1247 putative monovalent cation/H+ antiporter subunit C.


ensembl_gene_id: Metbo_0265
symbol: ADZ08517.1
gene_biotype: protein_coding
description:
  NADH dehydrogenase (quinone); KEGG: mth:MTH1246 hydrogenase subunit F; PFAM: NADH:ubiquinone/plastoquinone oxidoreductase.


ensembl_gene_id: Metbo_0268
symbol: ADZ08520.1
gene_biotype: protein_coding
description:
  PFAM: Na+/H+ antiporter MnhB subunit-related protein; KEGG: mmg:MTBMA_c16310 energy-converting hydrogenase B, subunit I.


ensembl_gene_id: Metbo_0271
symbol: ADZ08523.1
gene_biotype: protein_coding
description:
  4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; PFAM: 4Fe-4S binding domain; KEGG: mmg:MTBMA_c16280 energy-converting hydrogenase B, subunit L.


ensembl_gene_id: Metbo_0272
symbol: ADZ08524.1
gene_biotype: protein_coding
description:
  PFAM: NADH:ubiquinone oxidoreductase-like, 20kDa subunit; KEGG: mmg:MTBMA_c16270 energy-converting hydrogenase B, subunit M.


ensembl_gene_id: Metbo_0273
symbol: ADZ08525.1
gene_biotype: protein_coding
description:
  NADH dehydrogenase (quinone); KEGG: mmg:MTBMA_c16260 energy-converting hydrogenase B, subunit N; PFAM: Nickel-dependent hydrogenase, large subunit; NADH-quinone oxidoreductase, subunit D.


ensembl_gene_id: Metbo_0275
symbol: ADZ08527.1
gene_biotype: protein_coding
description:
  PFAM: Energy-converting hydrogenase B, subunit P; KEGG: msi:Msm_1061 energy-converting hydrogenase B, subunit P, EhbP.


ensembl_gene_id: Metbo_0276
symbol: ADZ08528.1
gene_biotype: protein_coding
description:
  PFAM: Glucose-methanol-choline oxidoreductase, N-terminal; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; 4Fe-4S binding domain; KEGG: shi:Shel_23820 choline dehydrogenase-like flavoprotein.


ensembl_gene_id: Metbo_0278
symbol: ADZ08530.1
gene_biotype: protein_coding
description:
  Long-chain-fatty-acid--CoA ligase; KEGG: shi:Shel_23800 AMP-forming long-chain acyl-CoA synthetase; PFAM: Male sterility, NAD-binding; AMP-dependent synthetase/ligase.


ensembl_gene_id: Metbo_0280
symbol: ADZ08532.1
gene_biotype: protein_coding
description:
  PFAM: Transcription regulator, TetR-like, DNA-binding, bacterial/archaeal; KEGG: rci:RCIX1914 TetR family transcriptional regulator.


ensembl_gene_id: Metbo_0288
symbol: ADZ08540.1
gene_biotype: protein_coding
description:
  PFAM: Homoserine dehydrogenase, catalytic; Aspartate/homoserine dehydrogenase, NAD-binding; Amino acid-binding ACT; KEGG: mmg:MTBMA_c16200 homoserine dehydrogenase.


ensembl_gene_id: Metbo_0289
symbol: ADZ08541.1
gene_biotype: protein_coding
description:
  DNA polymerase beta domain protein region; PFAM: Nucleotidyl transferase domain; KEGG: mth:MTH1231 hypothetical protein.


ensembl_gene_id: Metbo_0293
symbol: queE
gene_biotype: protein_coding
description:
  Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.


ensembl_gene_id: Metbo_0294
symbol: ADZ08546.1
gene_biotype: protein_coding
description:
  Putative signal transduction protein with CBS domains; KEGG: mth:MTH1226 inosine-5'-monophosphate dehydrogenase related protein V; PFAM: Cystathionine beta-synthase, core; SMART: Cystathionine beta-synthase, core.


ensembl_gene_id: Metbo_0295
symbol: ADZ08547.1
gene_biotype: protein_coding
description:
  Putative signal transduction protein with CBS domains; KEGG: mmg:MTBMA_c16100 CBS domain-containing protein; PFAM: Cystathionine beta-synthase, core; SMART: Cystathionine beta-synthase, core.


ensembl_gene_id: Metbo_0296
symbol: ADZ08548.1
gene_biotype: protein_coding
description:
  Putative signal transduction protein with CBS domains; KEGG: mmg:MTBMA_c16090 CBS domain-containing protein; PFAM: Cystathionine beta-synthase, core; SMART: Cystathionine beta-synthase, core.


ensembl_gene_id: Metbo_0297
symbol: ADZ08549.1
gene_biotype: protein_coding
description:
  Putative signal transduction protein with CBS domains; KEGG: mth:MTH1223 inosine-5'-monophosphate dehydrogenase related protein II; PFAM: Cystathionine beta-synthase, core; SMART: Cystathionine beta-synthase, core.


ensembl_gene_id: Metbo_0298
symbol: ADZ08550.1
gene_biotype: protein_coding
description:
  CBS domain containing membrane protein; KEGG: mth:MTH1222 inosine-5'-monophosphate dehydrogenase related protein I; PFAM: Cystathionine beta-synthase, core; SMART: Cystathionine beta-synthase, core.


ensembl_gene_id: Metbo_0299
symbol: ADZ08551.1
gene_biotype: protein_coding
description:
  Y414 protein; KEGG: mfv:Mfer_0241 ATP dependent DNA ligase; TIGRFAM: Uncharacterised protein family MJ0414; PFAM: DNA ligase, ATP-dependent, central.


ensembl_gene_id: Metbo_0300
symbol: ADZ08552.1
gene_biotype: protein_coding
description:
  KEGG: mmg:MTBMA_c16050 prephenate dehydratase; PFAM: Prephenate dehydratase; Amino acid-binding ACT.


ensembl_gene_id: Metbo_0304
symbol: ADZ08556.1
gene_biotype: protein_coding
description:
  TIGRFAM: Bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; KEGG: mth:MTH1216 pantothenate metabolism flavoprotein; PFAM: DNA/pantothenate metabolism flavoprotein, C-terminal; Flavoprotein.


ensembl_gene_id: Metbo_0305
symbol: flpA
gene_biotype: protein_coding
description:
  Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family.


ensembl_gene_id: Metbo_0306
symbol: ADZ08558.1
gene_biotype: protein_coding
description:
  KEGG: mru:mru_1987 pre-mRNA splicing ribonucleoprotein PRP31; PFAM: Pre-mRNA processing ribonucleoprotein, snoRNA-binding domain; NOSIC; SMART: NOSIC.


ensembl_gene_id: Metbo_0308
symbol: ADZ08560.1
gene_biotype: protein_coding
description:
  PFAM: Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain; Oxidoreductase FAD/NAD(P)-binding; Oxidoreductase, FAD-binding domain; KEGG: mfv:Mfer_1174 oxidoreductase fad/nad(P)-binding domain protein.


ensembl_gene_id: Metbo_0309
symbol: ADZ08561.1
gene_biotype: protein_coding
description:
  Protein of unknown function UPF0118; PFAM: Uncharacterised protein family UPF0118; KEGG: mmg:MTBMA_c15960 hypothetical protein.


ensembl_gene_id: Metbo_0311
symbol: hjc
gene_biotype: protein_coding
description:
  Resolvase, Holliday junction-type; A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products; Belongs to the Holliday junction resolvase Hjc family.


ensembl_gene_id: Metbo_0313
symbol: ADZ08565.1
gene_biotype: protein_coding
description:
  KEGG: mfv:Mfer_1224 radical sam domain protein; PFAM: Radical SAM; Biotin/thiamin synthesis-associated protein; SMART: Elongator protein 3/MiaB/NifB.


ensembl_gene_id: Metbo_0314
symbol: gatB
gene_biotype: protein_coding
description:
  Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily.


ensembl_gene_id: Metbo_0315
symbol: ADZ08567.1
gene_biotype: protein_coding
description:
  Putative signal transduction protein with CBS domains; KEGG: mmg:MTBMA_c16670 CBS domain containing protein; PFAM: Cystathionine beta-synthase, core; ParB-like nuclease; SMART: ParB-like nuclease; Cystathionine beta-synthase, core.


ensembl_gene_id: Metbo_0316
symbol: hisE
gene_biotype: protein_coding
description:
  TIGRFAM: Phosphoribosyl-ATP pyrophosphohydrolase; HAMAP: Phosphoribosyl-ATP pyrophosphohydrolase; KEGG: msi:Msm_1103 phosphoribosyl-ATP pyrophosphatase; PFAM: Phosphoribosyl-ATP pyrophosphohydrolase-like.


ensembl_gene_id: Metbo_0318
symbol: ADZ08570.1
gene_biotype: protein_coding
description:
  TIGRFAM: Sulfopyruvate decarboxylase, beta subunit; KEGG: mmg:MTBMA_c15850 sulfopyruvate decarboxylase, beta subunit; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding.


ensembl_gene_id: Metbo_0319
symbol: ADZ08571.1
gene_biotype: protein_coding
description:
  KEGG: msi:Msm_0080 sulfopyruvate decarboxylase, ComD; TIGRFAM: Sulfopyruvate decarboxylase, alpha subunit.


ensembl_gene_id: Metbo_0320
symbol: ADZ08572.1
gene_biotype: protein_coding
description:
  Malate dehydrogenase (NADP(+)); KEGG: mmg:MTBMA_c15830 sulfolactate dehydrogenase; PFAM: Malate/L-lactate dehydrogenase.


ensembl_gene_id: Metbo_0321
symbol: purM
gene_biotype: protein_coding
description:
  TIGRFAM: Phosphoribosylformylglycinamidine cyclo-ligase; KEGG: msi:Msm_1039 phosphoribosylaminoimidazole synthetase; PFAM: AIR synthase-related protein; AIR synthase-related protein, C-terminal.


ensembl_gene_id: Metbo_0322
symbol: ADZ08574.1
gene_biotype: protein_coding
description:
  TIGRFAM: KH-domain/beta-lactamase-domain protein, archaea; PFAM: Beta-lactamase-like; K Homology, type 1, subgroup; RNA-metabolising metallo-beta-lactamase; KEGG: mmg:MTBMA_c15810 metal-dependent RNase; SMART: Beta-lactamase-like; K Homology.


ensembl_gene_id: Metbo_0323
symbol: psmB
gene_biotype: protein_coding
description:
  Proteasome endopeptidase complex, beta subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.


ensembl_gene_id: Metbo_0324
symbol: purP
gene_biotype: protein_coding
description:
  5-formaminoimidazole-4-carboxamide-1-(beta)-D- ribofuranosyl 5'-monophosphate synthetase; Catalyzes the ATP- and formate-dependent formylation of 5- aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates.


ensembl_gene_id: Metbo_0325
symbol: taw2
gene_biotype: protein_coding
description:
  Protein of unknown function Met10; S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S- adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7- aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe).


ensembl_gene_id: Metbo_0326
symbol: ADZ08578.1
gene_biotype: protein_coding
description:
  TIGRFAM: PAS; PFAM: Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain; Signal transduction response regulator, receiver domain; PAS fold-4; ATPase-like, ATP-binding domain; KEGG: lic:LIC12627 histidine kinase response regulator hybrid protein; SMART: Signal transduction response regulator, receiver domain; PAS; ATPase-like, ATP-binding domain.


ensembl_gene_id: Metbo_0327
symbol: cofG
gene_biotype: protein_coding
description:
  FO synthase subunit 1; Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) from 5-amino-5-(4-hydroxybenzyl)-6-(D- ribitylimino)-5,6-dihydrouracil.


ensembl_gene_id: Metbo_0329
symbol: mptA
gene_biotype: protein_coding
description:
  Protein of unknown function DUF198; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin.


ensembl_gene_id: Metbo_0331
symbol: ADZ08583.1
gene_biotype: protein_coding
description:
  Transcriptional regulator, AsnC family; KEGG: mmg:MTBMA_c15710 transcriptional regulator; PFAM: Transcription regulator AsnC-type, C-terminal; SMART: Transcription regulator AsnC-type.


ensembl_gene_id: Metbo_0334
symbol: trm1
gene_biotype: protein_coding
description:
  N(2),N(2)-dimethylguanosine tRNA methyltransferase; Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.


ensembl_gene_id: Metbo_0336
symbol: ADZ08588.1
gene_biotype: protein_coding
description:
  Glutamine--scyllo-inositol transaminase; KEGG: mmg:MTBMA_c15650 pyridoxal phosphate-dependent enzyme; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; Belongs to the DegT/DnrJ/EryC1 family.


ensembl_gene_id: Metbo_0337
symbol: ADZ08589.1
gene_biotype: protein_coding
description:
  Protein of unknown function DUF77; KEGG: mmg:MTBMA_c15640 hypothetical protein; TIGRFAM: Protein of unknown function DUF77; PFAM: Protein of unknown function DUF77.


ensembl_gene_id: Metbo_0338
symbol: ADZ08590.1
gene_biotype: protein_coding
description:
  Protein of unknown function UPF0021; KEGG: msi:Msm_1028 ATPase; TIGRFAM: tRNA 2-thiolation protein; PFAM: tRNA(Ile)-lysidine/2-thiocytidine synthase.


ensembl_gene_id: Metbo_0339
symbol: ADZ08591.1
gene_biotype: protein_coding
description:
  PFAM: Protein synthesis factor, GTP-binding; Translation elongation factor EFTu/EF1A, domain 2; Translation elongation factor EFTu/EF1A, C-terminal; KEGG: mfv:Mfer_1241 translation elongation factor 1a gtp binding domain family.


ensembl_gene_id: Metbo_0341
symbol: ADZ08593.1
gene_biotype: protein_coding
description:
  PFAM: CDP-alcohol phosphatidyltransferase; KEGG: cbi:CLJ_B1067 CDP-alcohol phosphatidyltransferase family protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: Metbo_0342
symbol: ADZ08594.1
gene_biotype: protein_coding
description:
  KEGG: mru:mru_1950 TraB family protein; TIGRFAM: Pheromone shutdown, TraB; PFAM: Pheromone shutdown-related, TraB.


ensembl_gene_id: Metbo_0343
symbol: comB
gene_biotype: protein_coding
description:
  PFAM: 2-phosphosulpholactate phosphatase; TIGRFAM: 2-phosphosulpholactate phosphatase; HAMAP: 2-phosphosulpholactate phosphatase ComB; KEGG: mfv:Mfer_1236 2-phosphosulfolactate phosphatase.


ensembl_gene_id: Metbo_0344
symbol: ADZ08596.1
gene_biotype: protein_coding
description:
  PFAM: Deoxyribonuclease/rho motif-related TRAM; KEGG: mev:Metev_2175 deoxyribonuclease/rho motif-like TRAM protein.


ensembl_gene_id: Metbo_0346
symbol: ADZ08598.1
gene_biotype: protein_coding
description:
  Methanogenesis marker protein 7; TIGRFAM: Uncharacterised conserved protein UCP019164, methanogenesis; KEGG: mmg:MTBMA_c15570 methyl coenzyme M reductase II, operon protein C.


ensembl_gene_id: Metbo_0347
symbol: ADZ08599.1
gene_biotype: protein_coding
description:
  Metallophosphoesterase; PFAM: Metallo-dependent phosphatase; KEGG: mth:MTH1179 hypothetical protein.


ensembl_gene_id: Metbo_0348
symbol: ADZ08600.1
gene_biotype: protein_coding
description:
  Methanogenesis marker protein 10; KEGG: mmg:MTBMA_c15530 Fe-S oxidoreductase; TIGRFAM: Putative methanogenesis marker protein 10; PFAM: Domain of unknown function DUF512; Radical SAM.


ensembl_gene_id: Metbo_0349
symbol: ADZ08601.1
gene_biotype: protein_coding
description:
  TIGRFAM: Methyl-coenzyme M reductase, beta subunit; KEGG: mmg:MTBMA_c15520 methyl-coenzyme M reductase I, subunit beta; PFAM: Methyl-coenzyme M reductase, beta subunit, C-terminal; Methyl-coenzyme M reductase, beta subunit, N-terminal.


ensembl_gene_id: Metbo_0350
symbol: ADZ08602.1
gene_biotype: protein_coding
description:
  KEGG: mth:MTH1167 methyl coenzyme M reductase I, D protein; TIGRFAM: Methyl-coenzyme M reductase, protein D; PFAM: Methyl-coenzyme M reductase, protein D.


ensembl_gene_id: Metbo_0351
symbol: ADZ08603.1
gene_biotype: protein_coding
description:
  KEGG: mmg:MTBMA_c15500 methyl-coenzyme M reductase I, subunit epsilon; TIGRFAM: Methyl-coenzyme M reductase, protein C; PFAM: Methyl-coenzyme M reductase, protein C.


ensembl_gene_id: Metbo_0352
symbol: ADZ08604.1
gene_biotype: protein_coding
description:
  TIGRFAM: Methyl-coenzyme M reductase, gamma subunit; KEGG: mth:MTH1165 methyl coenzyme M reductase I, gamma subunit; PFAM: Methyl-coenzyme M reductase, gamma subunit.


ensembl_gene_id: Metbo_0353
symbol: ADZ08605.1
gene_biotype: protein_coding
description:
  Methyl-coenzyme M reductase, alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis.


ensembl_gene_id: Metbo_0354
symbol: mtrE
gene_biotype: protein_coding
description:
  Tetrahydromethanopterin S-methyltransferase subunit E; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.


ensembl_gene_id: Metbo_0355
symbol: mtrD
gene_biotype: protein_coding
description:
  Tetrahydromethanopterin S-methyltransferase subunit D; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.


ensembl_gene_id: Metbo_0356
symbol: mtrC
gene_biotype: protein_coding
description:
  Tetrahydromethanopterin S-methyltransferase, subunit C; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.


ensembl_gene_id: Metbo_0357
symbol: mtrB
gene_biotype: protein_coding
description:
  Tetrahydromethanopterin S-methyltransferase subunit B; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.


ensembl_gene_id: Metbo_0358
symbol: mtrA
gene_biotype: protein_coding
description:
  Tetrahydromethanopterin S-methyltransferase subunit A; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step; Belongs to the MtrA family.


ensembl_gene_id: Metbo_0359
symbol: mtrF
gene_biotype: protein_coding
description:
  Tetrahydromethanopterin S-methyltransferase, F subunit; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.


ensembl_gene_id: Metbo_0360
symbol: mtrG
gene_biotype: protein_coding
description:
  Tetrahydromethanopterin S-methyltransferase, subunit G; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.


ensembl_gene_id: Metbo_0361
symbol: mtrH
gene_biotype: protein_coding
description:
  Tetrahydromethanopterin S-methyltransferase subunit H; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. MtrH catalyzes the transfer of the methyl group from methyl-tetrahydromethanopterin to the corrinoid prosthetic group of MtrA.


ensembl_gene_id: Metbo_0362
symbol: ADZ08614.1
gene_biotype: protein_coding
description:
  Anion transporter; KEGG: mth:MTH788 sodium/dicarboxylate or sulfate cotransporter; TIGRFAM: Sodium/sulphate symporter; PFAM: Sodium/sulphate symporter.


ensembl_gene_id: Metbo_0363
symbol: ADZ08615.1
gene_biotype: protein_coding
description:
  Methanogenesis marker protein 14; KEGG: mth:MTH1153 hypothetical protein; TIGRFAM: Uncharacterised conserved protein UCP016937, methanogenesis; PFAM: Uncharacterised conserved protein UCP016937, methanogenesis.


ensembl_gene_id: Metbo_0364
symbol: ADZ08616.1
gene_biotype: protein_coding
description:
  PFAM: Acylneuraminate cytidylyltransferase; KEGG: mst:Msp_0310 GTP:adenosylcobinamide-phosphate guanylyltransferase.


ensembl_gene_id: Metbo_0366
symbol: ADZ08618.1
gene_biotype: protein_coding
description:
  SufBD protein; PFAM: SUF system FeS cluster assembly, SufBD; KEGG: mmg:MTBMA_c15340 ABC-type transport system, permease component.


ensembl_gene_id: Metbo_0367
symbol: ADZ08619.1
gene_biotype: protein_coding
description:
  KEGG: mth:MTH1149 ABC transporter subunit Ycf16; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core.


ensembl_gene_id: Metbo_0368
symbol: ADZ08620.1
gene_biotype: protein_coding
description:
  PFAM: Methyl-viologen-reducing hydrogenase, delta subunit; KEGG: mth:MTH1136 methyl viologen-reducing hydrogenase, delta subunit.


ensembl_gene_id: Metbo_0369
symbol: ADZ08621.1
gene_biotype: protein_coding
description:
  PFAM: NADH:ubiquinone oxidoreductase-like, 20kDa subunit; KEGG: msi:Msm_1000 methyl viologen-reducing hydrogenase, gamma subunit, MvhG.


ensembl_gene_id: Metbo_0370
symbol: ADZ08622.1
gene_biotype: protein_coding
description:
  Hydrogen dehydrogenase; KEGG: mmg:MTBMA_c15170 F420-non-reducing hydrogenase, subunit A; PFAM: Nickel-dependent hydrogenase, large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.


ensembl_gene_id: Metbo_0373
symbol: pyrC
gene_biotype: protein_coding
description:
  Dihydroorotase, multifunctional complex type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.


ensembl_gene_id: Metbo_0374
symbol: ADZ08626.1
gene_biotype: protein_coding
description:
  Protein of unknown function DUF795; PFAM: Uncharacterised protein family UPF0348; KEGG: mmg:MTBMA_c15090 nucleotidyltransferase.


ensembl_gene_id: Metbo_0375
symbol: ADZ08627.1
gene_biotype: protein_coding
description:
  PFAM: Peptidyl-prolyl cis-trans isomerase, FKBP-type; KEGG: mmg:MTBMA_c15080 peptidyl-prolyl cis-trans isomerase.


ensembl_gene_id: Metbo_0379
symbol: rpl10e
gene_biotype: protein_coding
description:
  TIGRFAM: Ribosomal protein L10e; HAMAP: Ribosomal protein L10e, archaea; KEGG: mmg:MTBMA_c15020 50S ribosomal protein L10e; PFAM: Ribosomal protein L10e/L16; Belongs to the universal ribosomal protein uL16 family.


ensembl_gene_id: Metbo_0380
symbol: ADZ08632.1
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.


ensembl_gene_id: Metbo_0381
symbol: mfnA
gene_biotype: protein_coding
description:
  L-tyrosine decarboxylase; Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis; Belongs to the group II decarboxylase family. MfnA subfamily.


ensembl_gene_id: Metbo_0382
symbol: ADZ08634.1
gene_biotype: protein_coding
description:
  PFAM: Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain; KEGG: msi:Msm_0929 fumarate hydratase, FumA.


ensembl_gene_id: Metbo_0383
symbol: ADZ08635.1
gene_biotype: protein_coding
description:
  TIGRFAM: Uracil phosphoribosyl transferase; KEGG: mmg:MTBMA_c14980 uracil phosphoribosyltransferase.


ensembl_gene_id: Metbo_0385
symbol: ADZ08637.1
gene_biotype: protein_coding
description:
  tRNA ribose 2'-O-methyltransferase aTrm56; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family.


ensembl_gene_id: Metbo_0386
symbol: cobS
gene_biotype: protein_coding
description:
  Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.


ensembl_gene_id: Metbo_0389
symbol: ADZ08641.1
gene_biotype: protein_coding
description:
  PFAM: Uncharacterised protein family, nitrogen regulatory protein PII-related; KEGG: mmg:MTBMA_c14940 transcriptional regulatory protein.


ensembl_gene_id: Metbo_0391
symbol: ADZ08643.1
gene_biotype: protein_coding
description:
  UPF0272 protein; TIGRFAM: Uncharacterised protein family UPF0272; HAMAP: Uncharacterised protein family UPF0272; KEGG: mth:MTH1109 hypothetical protein; PFAM: Uncharacterised protein family UPF0272; Belongs to the LarC family.


ensembl_gene_id: Metbo_0392
symbol: queC
gene_biotype: protein_coding
description:
  exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.


ensembl_gene_id: Metbo_0394
symbol: ADZ08646.1
gene_biotype: protein_coding
description:
  Roadblock/LC7 family protein; KEGG: mmg:MTBMA_c09750 regulator protein; PFAM: Dynein light chain-related; SMART: Dynein light chain-related.


ensembl_gene_id: Metbo_0395
symbol: ADZ08647.1
gene_biotype: protein_coding
description:
  TIGRFAM: Oxaloacetate decarboxylase, alpha subunit; KEGG: mmg:MTBMA_c14900 pyruvate carboxylase, subunit B; PFAM: Carboxylase, conserved domain; Pyruvate carboxyltransferase; Biotin/lipoyl attachment.


ensembl_gene_id: Metbo_0397
symbol: ADZ08649.1
gene_biotype: protein_coding
description:
  PFAM: Myo-inositol-1-phosphate synthase; Myo-inositol-1-phosphate synthase, GAPDH-like; KEGG: mmg:MTBMA_c14880 myo-inositol-1-phosphate synthase.


ensembl_gene_id: Metbo_0403
symbol: ef1b
gene_biotype: protein_coding
description:
  Elongation factor 1-beta; Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.


ensembl_gene_id: Metbo_0405
symbol: ADZ08657.1
gene_biotype: protein_coding
description:
  PFAM: Aspartate/glutamate/uridylate kinase; KEGG: mfv:Mfer_0582 aspartate/glutamate/uridylate kinase.


ensembl_gene_id: Metbo_0406
symbol: pth
gene_biotype: protein_coding
description:
  Peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.


ensembl_gene_id: Metbo_0407
symbol: ADZ08659.1
gene_biotype: protein_coding
description:
  KEGG: mmg:MTBMA_c13710 hypothetical protein; TIGRFAM: Putative methanogenesis marker protein 1; YcaO-like; PFAM: YcaO-like.


ensembl_gene_id: Metbo_0409
symbol: ADZ08661.1
gene_biotype: protein_coding
description:
  TIGRFAM: PAS; PFAM: Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain; PAS fold; ATPase-like, ATP-binding domain; KEGG: mmg:MTBMA_c13690 sensory transduction histidine kinase; SMART: ATPase-like, ATP-binding domain; PAS.


ensembl_gene_id: Metbo_0410
symbol: ADZ08662.1
gene_biotype: protein_coding
description:
  Alcohol dehydrogenase; KEGG: gur:Gura_3532 iron-containing alcohol dehydrogenase; PFAM: Alcohol dehydrogenase, iron-type.


ensembl_gene_id: Metbo_0412
symbol: ADZ08664.1
gene_biotype: protein_coding
description:
  PFAM: Peptidase M24, structural domain; Creatinase; KEGG: mfv:Mfer_0350 peptidase M24; Belongs to the peptidase M24B family.


ensembl_gene_id: Metbo_0415
symbol: ADZ08667.1
gene_biotype: protein_coding
description:
  Lactaldehyde dehydrogenase; KEGG: msi:Msm_0467 NADP-dependent glyceraldehyde-3-phosphate dehydrogenase; PFAM: Aldehyde dehydrogenase domain; Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: Metbo_0416
symbol: ADZ08668.1
gene_biotype: protein_coding
description:
  t-RNA-binding domain-containing protein; PFAM: tRNA-binding domain; KEGG: ton:TON_0446 putative tRNA-binding protein.


ensembl_gene_id: Metbo_0419
symbol: nadX
gene_biotype: protein_coding
description:
  L-aspartate dehydrogenase; Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.


ensembl_gene_id: Metbo_0420
symbol: ADZ08672.1
gene_biotype: protein_coding
description:
  Protein of unknown function DUF549; PFAM: tRNAHis guanylyltransferase; KEGG: mmg:MTBMA_c13580 hypothetical protein.


ensembl_gene_id: Metbo_0422
symbol: ADZ08674.1
gene_biotype: protein_coding
description:
  TIGRFAM: D-3-phosphoglycerate dehydrogenase; KEGG: mmg:MTBMA_c13560 phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; Amino acid-binding ACT.


ensembl_gene_id: Metbo_0423
symbol: ADZ08675.1
gene_biotype: protein_coding
description:
  UPF0145 protein ybjQ; KEGG: mmg:MTBMA_c09310 hypothetical protein; HAMAP: Uncharacterised protein family UPF0145; PFAM: Uncharacterised protein family UPF0145; Belongs to the UPF0145 family.


ensembl_gene_id: Metbo_0425
symbol: ADZ08677.1
gene_biotype: protein_coding
description:
  HAMAP: HTH transcriptional regulator, cro/C1-type DNA-binding domain-containing; PFAM: Helix-turn-helix type 3; KEGG: mmg:MTBMA_c13530 transcriptional regulator; SMART: Helix-turn-helix type 3.


ensembl_gene_id: Metbo_0426
symbol: tiaS
gene_biotype: protein_coding
description:
  Domain of unknown function DUF1743; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.


ensembl_gene_id: Metbo_0429
symbol: ADZ08681.1
gene_biotype: protein_coding
description:
  KEGG: mth:MTH963 fumarate hydratase, class I related protein; TIGRFAM: Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain; PFAM: Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain.


ensembl_gene_id: Metbo_0432
symbol: ADZ08684.1
gene_biotype: protein_coding
description:
  V-type ATPase 116 kDa subunit; KEGG: mth:MTH960 V-type ATP synthase subunit I; manually curated; PFAM: ATPase, V0/A0 complex, 116kDa subunit; Belongs to the V-ATPase 116 kDa subunit family.


ensembl_gene_id: Metbo_0433
symbol: ADZ08685.1
gene_biotype: protein_coding
description:
  KEGG: mmg:MTBMA_c13450 A1AO ATPase, subunit K; HAMAP: ATPase, F0 complex, subunit C; PFAM: ATPase, F0/V0 complex, subunit C; Belongs to the V-ATPase proteolipid subunit family.


ensembl_gene_id: Metbo_0434
symbol: atpE
gene_biotype: protein_coding
description:
  V-type proton ATPase subunit E; Produces ATP from ADP in the presence of a proton gradient across the membrane.


ensembl_gene_id: Metbo_0435
symbol: atpC
gene_biotype: protein_coding
description:
  V-type ATP synthase subunit C; Produces ATP from ADP in the presence of a proton gradient across the membrane.


ensembl_gene_id: Metbo_0436
symbol: atpF
gene_biotype: protein_coding
description:
  V-type ATP synthase subunit F; Produces ATP from ADP in the presence of a proton gradient across the membrane.


ensembl_gene_id: Metbo_0437
symbol: atpA
gene_biotype: protein_coding
description:
  V-type ATP synthase alpha chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family.


ensembl_gene_id: Metbo_0438
symbol: atpB
gene_biotype: protein_coding
description:
  V-type ATP synthase beta chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.


ensembl_gene_id: Metbo_0439
symbol: atpD
gene_biotype: protein_coding
description:
  V-type ATP synthase subunit D; Produces ATP from ADP in the presence of a proton gradient across the membrane.


ensembl_gene_id: Metbo_0442
symbol: ADZ08694.1
gene_biotype: protein_coding
description:
  Protein of unknown function DUF61; PFAM: Uncharacterised protein family UPF0216; KEGG: mth:MTH949 hypothetical protein; Belongs to the UPF0216 family.


ensembl_gene_id: Metbo_0448
symbol: ADZ08700.1
gene_biotype: protein_coding
description:
  TIGRFAM: PAS; PFAM: Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain; PAS fold; ATPase-like, ATP-binding domain; KEGG: rci:LRC120 signal transduction histidine kinase; SMART: ATPase-like, ATP-binding domain; PAS.


ensembl_gene_id: Metbo_0449
symbol: ADZ08701.1
gene_biotype: protein_coding
description:
  Protein of unknown function UPF0153; PFAM: Uncharacterised protein family UPF0153; KEGG: dly:Dehly_1145 hypothetical protein.


ensembl_gene_id: Metbo_0450
symbol: ADZ08702.1
gene_biotype: protein_coding
description:
  Putative PAS/PAC sensor protein; TIGRFAM: PAS; PFAM: PAS fold-4; KEGG: mpd:MCP_2190 putative signaling protein; SMART: PAS.


ensembl_gene_id: Metbo_0451
symbol: ADZ08703.1
gene_biotype: protein_coding
description:
  KEGG: mmg:MTBMA_c11840 transporter protein; TIGRFAM: Sodium/sulphate symporter; PFAM: Sodium/sulphate symporter.


ensembl_gene_id: Metbo_0452
symbol: ADZ08704.1
gene_biotype: protein_coding
description:
  KEGG: mmg:MTBMA_c14750 ABC transporter, permease component; TIGRFAM: Daunorubicin resistance ABC transporter membrane protein; PFAM: ABC-2 type transporter.


ensembl_gene_id: Metbo_0453
symbol: ADZ08705.1
gene_biotype: protein_coding
description:
  SMART: ATPase, AAA+ type, core; TIGRFAM: Daunorubicin resistance ABC transporter ATP-binding subunit; KEGG: mth:MTH1093 ABC transporter (ATP-binding protein); PFAM: ABC transporter-like.


ensembl_gene_id: Metbo_0454
symbol: ADZ08706.1
gene_biotype: protein_coding
description:
  Beta-lactamase domain protein; KEGG: mmg:MTBMA_c14810 hydrolase; PFAM: Beta-lactamase-like; Rhodanese-like; SMART: Beta-lactamase-like; Rhodanese-like.


ensembl_gene_id: Metbo_0462
symbol: cdhA
gene_biotype: protein_coding
description:
  Acetyl-CoA decarbonylase/synthase complex subunit alpha; Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase.


ensembl_gene_id: Metbo_0463
symbol: cdhB
gene_biotype: protein_coding
description:
  Acetyl-CoA decarbonylase/synthase complex subunit epsilon; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase. The precise role of the epsilon subunit is unclear; it may have a stabilizing role within the alpha(2)epsilon(2) component and/or be involved in electron transfer to FAD during a potential FAD-mediated CO oxidation. Belongs to the CdhB family.


ensembl_gene_id: Metbo_0464
symbol: cdhC
gene_biotype: protein_coding
description:
  CO dehydrogenase/acetyl-CoA synthase complex, beta subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl-CoA, is transferred to the beta subunit by a corrinoid iron-sulfur protein (the gamma-delta complex); Belongs to the CdhC family.


ensembl_gene_id: Metbo_0466
symbol: cdhD
gene_biotype: protein_coding
description:
  CO dehydrogenase/acetyl-CoA synthase, delta subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). Probably maintains the overall quaternary structure of the ACDS complex. Belongs to the CdhD family.


ensembl_gene_id: Metbo_0467
symbol: cdhE
gene_biotype: protein_coding
description:
  CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2).


ensembl_gene_id: Metbo_0468
symbol: ADZ08720.1
gene_biotype: protein_coding
description:
  PFAM: 4Fe-4S binding domain; KEGG: mmz:MmarC7_0221 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein.


ensembl_gene_id: Metbo_0469
symbol: ADZ08721.1
gene_biotype: protein_coding
description:
  KEGG: mfv:Mfer_0521 methylated-DNA/protein-cysteinemethyltransferase; TIGRFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding; PFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding.


ensembl_gene_id: Metbo_0470
symbol: ADZ08722.1
gene_biotype: protein_coding
description:
  KEGG: mmg:MTBMA_c02940 hypothetical protein; PFAM: PBS lyase HEAT-like repeat; SMART: PBS lyase HEAT-like repeat.


ensembl_gene_id: Metbo_0471
symbol: ADZ08723.1
gene_biotype: protein_coding
description:
  Digeranylgeranylglycerophospholipid reductase; Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3- diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di- O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains.


ensembl_gene_id: Metbo_0472
symbol: ADZ08724.1
gene_biotype: protein_coding
description:
  PFAM: 4Fe-4S binding domain; KEGG: mbn:Mboo_1946 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein.


ensembl_gene_id: Metbo_0473
symbol: ADZ08725.1
gene_biotype: protein_coding
description:
  Metallophosphoesterase; PFAM: Metallo-dependent phosphatase; KEGG: mmg:MTBMA_c02980 phosphohydrolase.


ensembl_gene_id: Metbo_0476
symbol: ADZ08728.1
gene_biotype: protein_coding
description:
  PFAM: Citrate synthase-like; KEGG: mmg:MTBMA_c03010 citrate synthase-related protein; Belongs to the citrate synthase family.


ensembl_gene_id: Metbo_0477
symbol: ADZ08729.1
gene_biotype: protein_coding
description:
  Phosphate binding protein; KEGG: mmg:MTBMA_c03020 extracellular phosphate-binding protein; TIGRFAM: Phosphate binding protein; PFAM: Bacterial extracellular solute-binding, family 1.


ensembl_gene_id: Metbo_0478
symbol: ADZ08730.1
gene_biotype: protein_coding
description:
  Phosphate ABC transporter, inner membrane subunit PstC; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: Metbo_0479
symbol: ADZ08731.1
gene_biotype: protein_coding
description:
  Phosphate ABC transporter, inner membrane subunit PstA; KEGG: mth:MTH1730 phosphate ABC transporter permease; TIGRFAM: Phosphate transport system permease protein 2; PFAM: Binding-protein-dependent transport systems inner membrane component.


ensembl_gene_id: Metbo_0480
symbol: pstB
gene_biotype: protein_coding
description:
  Phosphate ABC transporter, ATPase subunit; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.


ensembl_gene_id: Metbo_0484
symbol: ADZ08736.1
gene_biotype: protein_coding
description:
  TIGRFAM: Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain; KEGG: mth:MTH1735 fumarate hydratase; PFAM: Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain.


ensembl_gene_id: Metbo_0487
symbol: ADZ08739.1
gene_biotype: protein_coding
description:
  KEGG: mth:MTH1738 pyruvate ferredoxin oxidoreductase subunit beta; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding.


ensembl_gene_id: Metbo_0488
symbol: ADZ08740.1
gene_biotype: protein_coding
description:
  KEGG: mmg:MTBMA_c03140 pyruvate synthase, subunit A; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal.


ensembl_gene_id: Metbo_0489
symbol: ADZ08741.1
gene_biotype: protein_coding
description:
  KEGG: mmg:MTBMA_c03150 pyruvate synthase, subunit D; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate; PFAM: 4Fe-4S binding domain.


ensembl_gene_id: Metbo_0490
symbol: ADZ08742.1
gene_biotype: protein_coding
description:
  TIGRFAM: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate; KEGG: mth:MTH1740 pyruvate ferredoxin oxidoreductase subunit gamma/delta; PFAM: Pyruvate/ketoisovalerate oxidoreductase, catalytic domain.


ensembl_gene_id: Metbo_0491
symbol: ADZ08743.1
gene_biotype: protein_coding
description:
  KEGG: mth:MTH1741 hypothetical protein; TIGRFAM: Dihydropteroate synthase-related protein synthase-related protein; PFAM: Pterin-binding.


ensembl_gene_id: Metbo_0492
symbol: ADZ08744.1
gene_biotype: protein_coding
description:
  Protein of unknown function UPF0021; KEGG: mru:mru_0562 PP-loop family protein; TIGRFAM: tRNA 2-thiolation protein; PFAM: tRNA(Ile)-lysidine/2-thiocytidine synthase.


ensembl_gene_id: Metbo_0497
symbol: ADZ08749.1
gene_biotype: protein_coding
description:
  PFAM: Cytochrome c assembly protein, transmembrane domain; KEGG: mmg:MTBMA_c03220 cytochrome c-type biogenesis protein.


ensembl_gene_id: Metbo_0498
symbol: ADZ08750.1
gene_biotype: protein_coding
description:
  PFAM: Phosphogluconate dehydrogenase, NAD-binding, putative, C-terminal; NADP oxidoreductase, coenzyme F420-dependent; KEGG: mmg:MTBMA_c03230 dehydrogenase.


ensembl_gene_id: Metbo_0501
symbol: ADZ08753.1
gene_biotype: protein_coding
description:
  KEGG: mbn:Mboo_1858 MATE efflux family protein; TIGRFAM: Multi antimicrobial extrusion protein; PFAM: Multi antimicrobial extrusion protein.


ensembl_gene_id: Metbo_0502
symbol: ADZ08754.1
gene_biotype: protein_coding
description:
  Cytidyltransferase-related domain protein; KEGG: mmg:MTBMA_c03250 nucleotidyltransferase; TIGRFAM: Cytidyltransferase-related; PFAM: Cytidylyltransferase.


ensembl_gene_id: Metbo_0504
symbol: ADZ08756.1
gene_biotype: protein_coding
description:
  TIGRFAM: Conserved hypothetical protein CHP01210; PFAM: Radical SAM; KEGG: mmg:MTBMA_c03260 Fe-S oxidoreductase; SMART: Elongator protein 3/MiaB/NifB.


ensembl_gene_id: Metbo_0507
symbol: ADZ08759.1
gene_biotype: protein_coding
description:
  TIGRFAM: PAS; PFAM: Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain; PAS fold; ATPase-like, ATP-binding domain; KEGG: mmg:MTBMA_c12200 sensory transduction histidine kinase; SMART: PAS; ATPase-like, ATP-binding domain.


ensembl_gene_id: Metbo_0508
symbol: ADZ08760.1
gene_biotype: protein_coding
description:
  TIGRFAM: Methyl coenzyme M reductase system, component A2; PFAM: ABC transporter-like; KEGG: mmg:MTBMA_c13970 methyl-coenzyme M reductase, component A2; SMART: ATPase, AAA+ type, core.


ensembl_gene_id: Metbo_0509
symbol: ADZ08761.1
gene_biotype: protein_coding
description:
  UPF0251 protein; KEGG: mmg:MTBMA_c15550 DNA-binding protein; HAMAP: Uncharacterised protein family UPF0251; PFAM: Uncharacterised protein family UPF0251; Belongs to the UPF0251 family.


ensembl_gene_id: Metbo_0510
symbol: mer
gene_biotype: protein_coding
description:
  5,10-methylenetetrahydromethanopterin reductase; Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT; Belongs to the mer family.


ensembl_gene_id: Metbo_0512
symbol: mutS2
gene_biotype: protein_coding
description:
  DNA mismatch repair protein MutS domain protein; Has ATPase and non-specific DNA-binding activities. Belongs to the DNA mismatch repair MutS family. Archaeal Muts2 subfamily.


ensembl_gene_id: Metbo_0514
symbol: ADZ08766.1
gene_biotype: protein_coding
description:
  KEGG: mba:Mbar_A1826 hypothetical protein; PFAM: PBS lyase HEAT-like repeat; Tetratricopeptide TPR-1; SMART: PBS lyase HEAT-like repeat; Tetratricopeptide repeat.


ensembl_gene_id: Metbo_0516
symbol: ADZ08768.1
gene_biotype: protein_coding
description:
  Digeranylgeranylglyceryl phosphate synthase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids.


ensembl_gene_id: Metbo_0517
symbol: ADZ08769.1
gene_biotype: protein_coding
description:
  Uncharacterized protein family UPF0066; KEGG: afu:AF0241 hypothetical protein; TIGRFAM: Uncharacterised protein family UPF0066; PFAM: Uncharacterised protein family UPF0066.


ensembl_gene_id: Metbo_0519
symbol: ADZ08771.1
gene_biotype: protein_coding
description:
  Metal dependent phosphohydrolase; TIGRFAM: Uncharacterised protein family HDIG; PFAM: Metal-dependent phosphohydrolase, HD subdomain; Nucleic acid binding, OB-fold, tRNA/helicase-type; KEGG: mst:Msp_1165 hydrolase; SMART: Metal-dependent phosphohydrolase, HD domain.


ensembl_gene_id: Metbo_0524
symbol: tmk
gene_biotype: protein_coding
description:
  PFAM: Thymidylate kinase; TIGRFAM: Thymidylate kinase; HAMAP: Thymidylate kinase; KEGG: msi:Msm_0520 thymidylate kinase, Tmk.


ensembl_gene_id: Metbo_0526
symbol: tyrS
gene_biotype: protein_coding
description:
  Tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 3 subfamily.


ensembl_gene_id: Metbo_0528
symbol: eif2b
gene_biotype: protein_coding
description:
  Translation initiation factor 2 subunit beta; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-beta/eIF-5 family.


ensembl_gene_id: Metbo_0529
symbol: ADZ08781.1
gene_biotype: protein_coding
description:
  KEGG: mfv:Mfer_0045 mcm family protein; PFAM: DNA-dependent ATPase MCM; SMART: DNA-dependent ATPase MCM; Hedgehog/intein hint, N-terminal; Hedgehog/intein hint domain, C-terminal; Belongs to the MCM family.


ensembl_gene_id: Metbo_0531
symbol: rlmE
gene_biotype: protein_coding
description:
  Ribosomal RNA large subunit methyltransferase E; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.


ensembl_gene_id: Metbo_0532
symbol: ADZ08784.1
gene_biotype: protein_coding
description:
  Phosphodiesterase, MJ0936 family; KEGG: mth:MTH1774 hypothetical protein; TIGRFAM: Phosphodiesterase MJ0936; PFAM: Metallo-dependent phosphatase.


ensembl_gene_id: Metbo_0533
symbol: topA
gene_biotype: protein_coding
description:
  DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]


ensembl_gene_id: Metbo_0534
symbol: ADZ08786.1
gene_biotype: protein_coding
description:
  PFAM: Oligosaccharyl transferase, STT3 subunit; KEGG: mmg:MTBMA_c02090 oligosaccharyl transferase STT3 subunit related protein.


ensembl_gene_id: Metbo_0535
symbol: ADZ08787.1
gene_biotype: protein_coding
description:
  Small GTP-binding protein; KEGG: mth:MTH1621 GTP1/OBG family GTP-binding protein; TIGRFAM: Small GTP-binding protein; PFAM: GTP-binding protein, HSR1-related; TGS.


ensembl_gene_id: Metbo_0536
symbol: thi4
gene_biotype: protein_coding
description:
  Thiazole biosynthetic enzyme; Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur.


ensembl_gene_id: Metbo_0537
symbol: ADZ08789.1
gene_biotype: protein_coding
description:
  Adenylate kinase; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Belongs to the adenylate kinase family. AK6 subfamily.


ensembl_gene_id: Metbo_0538
symbol: rnp4
gene_biotype: protein_coding
description:
  Ribonuclease P protein component 4; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.


ensembl_gene_id: Metbo_0539
symbol: ADZ08791.1
gene_biotype: protein_coding
description:
  Protein of unknown function UPF0044; PFAM: RNA-binding, CRM domain; KEGG: mmg:MTBMA_c02030 RNA-binding protein.


ensembl_gene_id: Metbo_0540
symbol: rps19e
gene_biotype: protein_coding
description:
  Ribosomal protein S19e; May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family.


ensembl_gene_id: Metbo_0541
symbol: ADZ08793.1
gene_biotype: protein_coding
description:
  KEGG: mth:MTH1615 hypothetical protein; HAMAP: DNA-binding protein, archaea; PFAM: DNA-binding TFAR19-related protein; Belongs to the PDCD5 family.


ensembl_gene_id: Metbo_0542
symbol: ADZ08794.1
gene_biotype: protein_coding
description:
  Queuosine synthesis-like protein; PFAM: Queuosine synthesis; KEGG: mfv:Mfer_0169 queuosine synthesis.


ensembl_gene_id: Metbo_0543
symbol: rpl39e
gene_biotype: protein_coding
description:
  KEGG: tga:TGAM_1684 50S ribosomal protein L39e; HAMAP: 50S ribosomal protein L39e; PFAM: Ribosomal protein L39e; Belongs to the eukaryotic ribosomal protein eL39 family.


ensembl_gene_id: Metbo_0544
symbol: rpl31e
gene_biotype: protein_coding
description:
  KEGG: mfv:Mfer_0167 lsu ribosomal protein l31e; HAMAP: Ribosomal protein L31e; PFAM: Ribosomal protein L31e; Belongs to the ribosomal protein L31e family.


ensembl_gene_id: Metbo_0545
symbol: eif6
gene_biotype: protein_coding
description:
  Translation initiation factor 6; Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.


ensembl_gene_id: Metbo_0547
symbol: pfdA
gene_biotype: protein_coding
description:
  Prefoldin subunit alpha; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.


ensembl_gene_id: Metbo_0548
symbol: ftsY
gene_biotype: protein_coding
description:
  Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).


ensembl_gene_id: Metbo_0551
symbol: ADZ08803.1
gene_biotype: protein_coding
description:
  dUTP diphosphatase; KEGG: msi:Msm_0687 deoxycytidine-triphosphate deaminase, dcd; PFAM: DeoxyUTP pyrophosphatase domain.


ensembl_gene_id: Metbo_0554
symbol: nadA
gene_biotype: protein_coding
description:
  Quinolinate synthase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.


ensembl_gene_id: Metbo_0555
symbol: ADZ08807.1
gene_biotype: protein_coding
description:
  Methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine.


ensembl_gene_id: Metbo_0556
symbol: rtcB
gene_biotype: protein_coding
description:
  Protein of unknown function UPF0027; PFAM: Uncharacterised protein family UPF0027; KEGG: mth:MTH1597 hypothetical protein; Belongs to the RtcB family.


ensembl_gene_id: Metbo_0557
symbol: ADZ08809.1
gene_biotype: protein_coding
description:
  KEGG: tpd:Teth39_0972 beta-lactamase domain-containing protein; PFAM: Beta-lactamase-like; SMART: Beta-lactamase-like.


ensembl_gene_id: Metbo_0560
symbol: ADZ08812.1
gene_biotype: protein_coding
description:
  Protein of unknown function DUF101; Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently.


ensembl_gene_id: Metbo_0563
symbol: mptE
gene_biotype: protein_coding
description:
  Protein of unknown function DUF115; Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl- 7,8-dihydropterin diphosphate (6-HMDP); Belongs to the archaeal 6-HMPDK family.


ensembl_gene_id: Metbo_0564
symbol: ADZ08815.1
gene_biotype: protein_coding
description:
  Serine--pyruvate transaminase; KEGG: mmg:MTBMA_c01880 aminotransferase; PFAM: Aminotransferase, class V/Cysteine desulfurase.


ensembl_gene_id: Metbo_0565
symbol: ADZ08816.1
gene_biotype: protein_coding
description:
  Radical SAM domain protein; KEGG: msi:Msm_0385 anaerobic magnesium-protoporphyrin IX monomethyl ester cyclase elongator protein; PFAM: Radical SAM; Cobalamin (vitamin B12)-binding; SMART: Elongator protein 3/MiaB/NifB.


ensembl_gene_id: Metbo_0566
symbol: ADZ08817.1
gene_biotype: protein_coding
description:
  KEGG: mfv:Mfer_0624 acetolactate synthase; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding; Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain; Thiamine pyrophosphate enzyme, central domain.


ensembl_gene_id: Metbo_0567
symbol: ADZ08818.1
gene_biotype: protein_coding
description:
  TIGRFAM: Acetate-CoA ligase; KEGG: mmg:MTBMA_c01900 acetyl-coenzyme A synthetase; PFAM: AMP-dependent synthetase/ligase.


ensembl_gene_id: Metbo_0569
symbol: ADZ08820.1
gene_biotype: protein_coding
description:
  KEGG: mmg:MTBMA_c10460 nitrogen regulatory protein GlnK; PFAM: Nitrogen regulatory protein PII; SMART: Nitrogen regulatory protein PII; Belongs to the P(II) protein family.


ensembl_gene_id: Metbo_0570
symbol: ADZ08821.1
gene_biotype: protein_coding
description:
  KEGG: mmg:MTBMA_c10450 ammonium transporter; TIGRFAM: Ammonium transporter; PFAM: Ammonium transporter.


ensembl_gene_id: Metbo_0573
symbol: ADZ08824.1
gene_biotype: protein_coding
description:
  KEGG: mmg:MTBMA_c06450 glutamate synthase, subunit 2; PFAM: Glutamate synthase, central-C; 4Fe-4S binding domain; Belongs to the glutamate synthase family.


ensembl_gene_id: Metbo_0574
symbol: ADZ08825.1
gene_biotype: protein_coding
description:
  Coenzyme F420 hydrogenase; KEGG: mmg:MTBMA_c06440 F420-dependent glutamate synthase; PFAM: Coenzyme F420 hydrogenase/dehydrogenase beta subunit, C-terminal; 4Fe-4S binding domain; Coenzyme F420 hydrogenase/dehydrogenase beta subunit, N-terminal.


ensembl_gene_id: Metbo_0575
symbol: ADZ08826.1
gene_biotype: protein_coding
description:
  PFAM: Glutamate synthase, alpha subunit, C-terminal; KEGG: mth:MTH192 tungsten formylmethanofuran dehydrogenase, subunit C-like protein.


ensembl_gene_id: Metbo_0577
symbol: pdxT
gene_biotype: protein_coding
description:
  Glutamine amidotransferase subunit pdxT; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.


ensembl_gene_id: Metbo_0579
symbol: ADZ08830.1
gene_biotype: protein_coding
description:
  HAMAP: Malate dehydrogenase, NAD-dependent; KEGG: mmg:MTBMA_c06400 malate dehydrogenase; PFAM: Lactate/malate dehydrogenase, N-terminal; Lactate/malate dehydrogenase, C-terminal; Belongs to the LDH/MDH superfamily.


ensembl_gene_id: Metbo_0581
symbol: ADZ08832.1
gene_biotype: protein_coding
description:
  TIGRFAM: Isopropylmalate/isohomocitrate dehydrogenase; KEGG: mth:MTH184 multifunctional 3-isopropylmalate dehydrogenase/D-malate dehydrogenase; PFAM: Isocitrate/isopropylmalate dehydrogenase.


ensembl_gene_id: Metbo_0582
symbol: fbp
gene_biotype: protein_coding
description:
  Protein of unknown function DUF100; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).


ensembl_gene_id: Metbo_0584
symbol: ADZ08835.1
gene_biotype: protein_coding
description:
  Protein of unknown function DUF47; KEGG: mmg:MTBMA_c02670 hypothetical protein; TIGRFAM: Protein of unknown function DUF47; PFAM: Putitive phosphate transport regulator.


ensembl_gene_id: Metbo_0586
symbol: ADZ08837.1
gene_biotype: protein_coding
description:
  PFAM: CDP-alcohol phosphatidyltransferase; KEGG: mru:mru_0503 phosphatidylglycerophosphate synthase PgsA; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: Metbo_0587
symbol: ADZ08838.1
gene_biotype: protein_coding
description:
  Sua5/YciO/YrdC/YwlC family protein; KEGG: mfv:Mfer_1131 translation factor SUA5; TIGRFAM: Sua5/YciO/YrdC/YwlC; PFAM: Sua5/YciO/YrdC, N-terminal.


ensembl_gene_id: Metbo_0588
symbol: radB
gene_biotype: protein_coding
description:
  DNA repair and recombination protein radB; Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange.


ensembl_gene_id: Metbo_0592
symbol: ADZ08843.1
gene_biotype: protein_coding
description:
  Manually curated; PFAM: ABC transporter-like; RNase L inhibitor RLI, possible metal-binding domain; 4Fe-4S binding domain; KEGG: mth:MTH1695 putative ATPase RIL; SMART: ATPase, AAA+ type, core.


ensembl_gene_id: Metbo_0593
symbol: ADZ08844.1
gene_biotype: protein_coding
description:
  Transcription factor CBF/NF-Y/histone domain-containing protein; PFAM: Transcription factor CBF/NF-Y/archaeal histone; KEGG: mmg:MTBMA_c02740 archaeal histone.


ensembl_gene_id: Metbo_0594
symbol: ADZ08845.1
gene_biotype: protein_coding
description:
  YbhB YbcL family protein; KEGG: sat:SYN_03131 phosphatidylethanolamine-binding protein; TIGRFAM: YbhB/YbcL; PFAM: Phosphatidylethanolamine-binding protein PEBP.


ensembl_gene_id: Metbo_0597
symbol: argH
gene_biotype: protein_coding
description:
  PFAM: Lyase 1, N-terminal; TIGRFAM: Argininosuccinate lyase; HAMAP: Argininosuccinate lyase; KEGG: mmg:MTBMA_c07190 argininosuccinate lyase.


ensembl_gene_id: Metbo_0598
symbol: rps27ae
gene_biotype: protein_coding
description:
  KEGG: mst:Msp_0620 30S ribosomal protein S27ae; HAMAP: Ribosomal protein S27ae; PFAM: Ribosomal protein S27a; Belongs to the eukaryotic ribosomal protein eS31 family.


ensembl_gene_id: Metbo_0599
symbol: rps24e
gene_biotype: protein_coding
description:
  KEGG: mth:MTH267 30S ribosomal protein S24e; HAMAP: 30S ribosomal protein S24e; PFAM: Ribosomal protein S24e; Belongs to the eukaryotic ribosomal protein eS24 family.


ensembl_gene_id: Metbo_0600
symbol: ADZ08851.1
gene_biotype: protein_coding
description:
  UPF0218 protein; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).


ensembl_gene_id: Metbo_0601
symbol: spt4
gene_biotype: protein_coding
description:
  DNA-dependent RNA polymerase, subunit E'; Stimulates transcription elongation; Belongs to the archaeal Spt4 family.


ensembl_gene_id: Metbo_0602
symbol: ADZ08853.1
gene_biotype: protein_coding
description:
  SMART: RNA-binding domain, S1; TIGRFAM: DNA-directed RNA polymerase; KEGG: mmg:MTBMA_c07140 DNA-directed RNA polymerase subunit E'; PFAM: RNA polymerase Rpb7, N-terminal; Ribosomal protein S1, RNA-binding domain.


ensembl_gene_id: Metbo_0603
symbol: ppa
gene_biotype: protein_coding
description:
  Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.


ensembl_gene_id: Metbo_0605
symbol: eif2g
gene_biotype: protein_coding
description:
  Translation initiation factor 2 subunit gamma; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily.


ensembl_gene_id: Metbo_0606
symbol: rps6e
gene_biotype: protein_coding
description:
  KEGG: mth:MTH260 30S ribosomal protein S6e; HAMAP: 30S ribosomal protein S6e; PFAM: Ribosomal protein S6e; Belongs to the eukaryotic ribosomal protein eS6 family.


ensembl_gene_id: Metbo_0607
symbol: infB
gene_biotype: protein_coding
description:
  Translation initiation factor aIF-2; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2.


ensembl_gene_id: Metbo_0608
symbol: ndk
gene_biotype: protein_coding
description:
  Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.


ensembl_gene_id: Metbo_0610
symbol: rps28e
gene_biotype: protein_coding
description:
  KEGG: mst:Msp_0632 30S ribosomal protein S28e; HAMAP: Ribosomal protein S28e, archaeal; PFAM: Ribosomal protein S28e; Belongs to the eukaryotic ribosomal protein eS28 family.


ensembl_gene_id: Metbo_0611
symbol: rpl7ae
gene_biotype: protein_coding
description:
  50S ribosomal protein L7Ae; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.


ensembl_gene_id: Metbo_0612
symbol: ADZ08863.1
gene_biotype: protein_coding
description:
  KEGG: mth:MTH1696 histone HMtA2; PFAM: Transcription factor CBF/NF-Y/archaeal histone; SMART: TATA box binding protein associated factor (TAF).


ensembl_gene_id: Metbo_0613
symbol: ADZ08864.1
gene_biotype: protein_coding
description:
  Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.


ensembl_gene_id: Metbo_0614
symbol: ADZ08865.1
gene_biotype: protein_coding
description:
  PFAM: Protein of unknown function DUF95, transmembrane; KEGG: mmg:MTBMA_c07020 hypothetical protein.


ensembl_gene_id: Metbo_0616
symbol: endA
gene_biotype: protein_coding
description:
  tRNA-splicing endonuclease; Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.


ensembl_gene_id: Metbo_0617
symbol: ADZ08868.1
gene_biotype: protein_coding
description:
  TIGRFAM: 6-phospho 3-hexuloisomerase; KEGG: mmg:MTBMA_c06990 3-hexulose-6-phosphate isomerase; PFAM: Sugar isomerase (SIS).


ensembl_gene_id: Metbo_0618
symbol: ADZ08869.1
gene_biotype: protein_coding
description:
  NADPH-dependent F420 reductase; KEGG: mth:MTH248 hypothetical protein; TIGRFAM: NADPH-dependent F420 reductase; PFAM: NADP oxidoreductase, coenzyme F420-dependent.


ensembl_gene_id: Metbo_0619
symbol: ADZ08870.1
gene_biotype: protein_coding
description:
  PFAM: Xylose isomerase, TIM barrel domain; KEGG: mfv:Mfer_1192 xylose isomerase domain protein tim barrel.


ensembl_gene_id: Metbo_0621
symbol: hisI
gene_biotype: protein_coding
description:
  Phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.


ensembl_gene_id: Metbo_0622
symbol: hisS
gene_biotype: protein_coding
description:
  ATP phosphoribosyltransferase regulatory subunit; PFAM: Aminoacyl-tRNA synthetase, class II (G/ H/ P/ S), conserved domain; Anticodon-binding; TIGRFAM: Histidyl-tRNA synthetase, class IIa, subgroup; HAMAP: ATP phosphoribosyltransferase regulatory subunit; Histidyl-tRNA synthetase, class IIa, subgroup; KEGG: mth:MTH244 histidyl-tRNA synthetase.


ensembl_gene_id: Metbo_0623
symbol: ADZ08874.1
gene_biotype: protein_coding
description:
  UPF0278 protein; RNA-free RNase P that catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. Belongs to the HARP family.


ensembl_gene_id: Metbo_0624
symbol: aroE
gene_biotype: protein_coding
description:
  Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).


ensembl_gene_id: Metbo_0626
symbol: ADZ08877.1
gene_biotype: protein_coding
description:
  KEGG: mth:MTH561 hypothetical protein; TIGRFAM: Conserved hypothetical protein CHP00267; PFAM: Domain of unknown function DUF125, transmembrane.


ensembl_gene_id: Metbo_0627
symbol: ADZ08878.1
gene_biotype: protein_coding
description:
  TIGRFAM: Hydroxymethylglutaryl-CoA reductase, eukaryotic/arcaheal type; KEGG: mfv:Mfer_0012 3-hydroxy-3-methylglutaryl-coenzyme a reductase; PFAM: Hydroxymethylglutaryl-CoA reductase, class I/II; Belongs to the HMG-CoA reductase family.


ensembl_gene_id: Metbo_0628
symbol: sucD
gene_biotype: protein_coding
description:
  succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.


ensembl_gene_id: Metbo_0630
symbol: aroD
gene_biotype: protein_coding
description:
  3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family.


ensembl_gene_id: Metbo_0631
symbol: ADZ08882.1
gene_biotype: protein_coding
description:
  Protein of unknown function DUF2196; KEGG: bbe:BBR47_50740 hypothetical protein; TIGRFAM: Protein of unknown function DUF2196; PFAM: Protein of unknown function DUF2196.


ensembl_gene_id: Metbo_0632
symbol: htpX
gene_biotype: protein_coding
description:
  Protease htpX; KEGG: mmg:MTBMA_c09550 heat shock protein; HAMAP: Peptidase M48, protease HtpX, putative; PFAM: Peptidase M48; Belongs to the peptidase M48B family.


ensembl_gene_id: Metbo_0633
symbol: ADZ08884.1
gene_biotype: protein_coding
description:
  PFAM: SNARE associated Golgi protein; KEGG: mfv:Mfer_1129 SNARE associated golgi protein-like protein.


ensembl_gene_id: Metbo_0634
symbol: ADZ08885.1
gene_biotype: protein_coding
description:
  PFAM: Glutamate synthase, alpha subunit, C-terminal; KEGG: mfv:Mfer_0106 glutamate synthase alpha subunit domain protein.


ensembl_gene_id: Metbo_0636
symbol: rfcL
gene_biotype: protein_coding
description:
  Replication factor C large subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcL subfamily.


ensembl_gene_id: Metbo_0637
symbol: rfcS
gene_biotype: protein_coding
description:
  Replication factor C small subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcS subfamily.


ensembl_gene_id: Metbo_0638
symbol: ADZ08889.1
gene_biotype: protein_coding
description:
  Roadblock/LC7 family protein; KEGG: mmg:MTBMA_c03980 hypothetical protein; PFAM: Dynein light chain-related; SMART: Dynein light chain-related.


ensembl_gene_id: Metbo_0639
symbol: ADZ08890.1
gene_biotype: protein_coding
description:
  Hydrogen dehydrogenase; KEGG: mpd:MCP_2492 F420-non-reducing hydrogenase subunit A; PFAM: Nickel-dependent hydrogenase, large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.


ensembl_gene_id: Metbo_0640
symbol: ADZ08891.1
gene_biotype: protein_coding
description:
  PFAM: NADH:ubiquinone oxidoreductase-like, 20kDa subunit; KEGG: mpd:MCP_2493 F420-non-reducing hydrogenase subunit G.


ensembl_gene_id: Metbo_0642
symbol: ADZ08893.1
gene_biotype: protein_coding
description:
  PFAM: 4Fe-4S binding domain; KEGG: mpi:Mpet_2721 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein.


ensembl_gene_id: Metbo_0645
symbol: rnz
gene_biotype: protein_coding
description:
  Ribonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family.


ensembl_gene_id: Metbo_0646
symbol: ADZ08897.1
gene_biotype: protein_coding
description:
  Nicotinate-nucleotide pyrophosphorylase; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family.


ensembl_gene_id: Metbo_0650
symbol: ADZ08901.1
gene_biotype: protein_coding
description:
  TIGRFAM: Zinc finger, ZPR1-type, subgroup; Zinc finger, ZPR1-type; KEGG: mmg:MTBMA_c04040 hypothetical protein.


ensembl_gene_id: Metbo_0651
symbol: ADZ08902.1
gene_biotype: protein_coding
description:
  3H domain-containing protein; PFAM: 3H domain; KEGG: mmg:MTBMA_c04050 2-phosphoglycerate kinase related protein with an additional conserved domain.


ensembl_gene_id: Metbo_0652
symbol: ADZ08903.1
gene_biotype: protein_coding
description:
  Roadblock/LC7 family protein; KEGG: mmg:MTBMA_c04060 regulator protein; PFAM: Dynein light chain-related; SMART: Dynein light chain-related.


ensembl_gene_id: Metbo_0656
symbol: ADZ08907.1
gene_biotype: protein_coding
description:
  Cell division ATPase MinD; KEGG: mmg:MTBMA_c04100 iron-sulfur cluster carrier protein; TIGRFAM: ATPase, cell division-type, MinD; PFAM: Cobyrinic acid a,c-diamide synthase.


ensembl_gene_id: Metbo_0657
symbol: ADZ08908.1
gene_biotype: protein_coding
description:
  KEGG: mth:MTH1840 cell division inhibitor; TIGRFAM: ATPase, cell division-type, MinD; PFAM: Cobyrinic acid a,c-diamide synthase.


ensembl_gene_id: Metbo_0658
symbol: ADZ08909.1
gene_biotype: protein_coding
description:
  PfkB domain protein; PFAM: Carbohydrate/purine kinase; KEGG: mfv:Mfer_0308 PfkB domain protein; Belongs to the carbohydrate kinase PfkB family.


ensembl_gene_id: Metbo_0660
symbol: ADZ08911.1
gene_biotype: protein_coding
description:
  KEGG: mfv:Mfer_0910 phosphoesterase pa-phosphatase related protein; PFAM: Phosphatidic acid phosphatase type 2/haloperoxidase; SMART: Phosphatidic acid phosphatase type 2/haloperoxidase.


ensembl_gene_id: Metbo_0661
symbol: ADZ08912.1
gene_biotype: protein_coding
description:
  KEGG: mmg:MTBMA_c04160 glycyl-tRNA synthetase; TIGRFAM: Glycyl-tRNA synthetase, alpha2 dimer; PFAM: Aminoacyl-tRNA synthetase, class II (G/ H/ P/ S), conserved domain; Anticodon-binding.


ensembl_gene_id: Metbo_0662
symbol: dcd
gene_biotype: protein_coding
description:
  Deoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.


ensembl_gene_id: Metbo_0663
symbol: ADZ08914.1
gene_biotype: protein_coding
description:
  KEGG: mst:Msp_1047 rRNA methylase; TIGRFAM: RNA methyltransferase TrmH, group 1; PFAM: tRNA/rRNA methyltransferase, SpoU.


ensembl_gene_id: Metbo_0664
symbol: ADZ08915.1
gene_biotype: protein_coding
description:
  TIGRFAM: Succinate dehydrogenase/fumarate reductase iron-sulphur protein; KEGG: mmg:MTBMA_c04210 thiol:fumarate reductase, subunit B; PFAM: Cysteine-rich domain; Ferredoxin.


ensembl_gene_id: Metbo_0666
symbol: ADZ08917.1
gene_biotype: protein_coding
description:
  Indolepyruvate ferredoxin oxidoreductase, alpha subunit; Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.


ensembl_gene_id: Metbo_0667
symbol: ADZ08918.1
gene_biotype: protein_coding
description:
  TIGRFAM: Indolepyruvate ferredoxin oxidoreductase, beta subunit; KEGG: mst:Msp_1042 indolepyruvate oxidoreductase subunit beta; PFAM: Pyruvate/ketoisovalerate oxidoreductase, catalytic domain.


ensembl_gene_id: Metbo_0669
symbol: ADZ08920.1
gene_biotype: protein_coding
description:
  Phenylacetate--CoA ligase; KEGG: mth:MTH161 coenzyme F390 synthetase III; PFAM: AMP-dependent synthetase/ligase.


ensembl_gene_id: Metbo_0670
symbol: ADZ08921.1
gene_biotype: protein_coding
description:
  SSS sodium solute transporter superfamily; KEGG: mmg:MTBMA_c04260 Na+/solute symporter; TIGRFAM: Sodium/solute symporter, subgroup; PFAM: Sodium/solute symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: Metbo_0671
symbol: ADZ08922.1
gene_biotype: protein_coding
description:
  KEGG: sus:Acid_4279 beta-lactamase domain-containing protein; PFAM: Beta-lactamase-like; SMART: Beta-lactamase-like.


ensembl_gene_id: Metbo_0676
symbol: ADZ08927.1
gene_biotype: protein_coding
description:
  SSS sodium solute transporter superfamily; KEGG: mth:MTH1856 sodium/proline symporter (proline permease); TIGRFAM: Sodium/solute symporter, subgroup; PFAM: Sodium/solute symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: Metbo_0679
symbol: pyrE
gene_biotype: protein_coding
description:
  Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).


ensembl_gene_id: Metbo_0680
symbol: ADZ08931.1
gene_biotype: protein_coding
description:
  TIGRFAM: Molybdenum cofactor synthesis; PFAM: Molybdopterin binding; KEGG: mth:MTH1861 molybdenum cofactor biosynthesis MoaB; SMART: Molybdopterin binding.


ensembl_gene_id: Metbo_0683
symbol: ADZ08934.1
gene_biotype: protein_coding
description:
  Methanogenesis marker protein 2; KEGG: mmg:MTBMA_c04350 SelD-related protein; TIGRFAM: Putative methanogenesis marker protein 2; PFAM: AIR synthase-related protein; AIR synthase-related protein, C-terminal.


ensembl_gene_id: Metbo_0684
symbol: ADZ08935.1
gene_biotype: protein_coding
description:
  UPF0288 protein; KEGG: mmg:MTBMA_c04360 peptidyl-prolyl cis-trans isomerase related protein; TIGRFAM: Uncharacterised protein family UPF0288, methanogenesis; HAMAP: Uncharacterised protein family UPF0288, methanogenesis; Belongs to the UPF0288 family.


ensembl_gene_id: Metbo_0685
symbol: ADZ08936.1
gene_biotype: protein_coding
description:
  KEGG: mfv:Mfer_1092 methanogenesis marker protein 6; TIGRFAM: Uncharacterised conserved protein UCP005642, methanogenesis; PFAM: Uncharacterised conserved protein UCP005642, methanogenesis.


ensembl_gene_id: Metbo_0686
symbol: ADZ08937.1
gene_biotype: protein_coding
description:
  PFAM: Uncharacterised conserved protein UCP006557, signal transduction; KEGG: mfv:Mfer_1093 hypothetical protein.


ensembl_gene_id: Metbo_0687
symbol: ADZ08938.1
gene_biotype: protein_coding
description:
  Methanogenesis marker protein 5; KEGG: mth:MTH1868 hypothetical protein; TIGRFAM: Uncharacterised conserved protein UCP018781, methanogenesis; PFAM: Uncharacterised conserved protein UCP018781, methanogenesis.


ensembl_gene_id: Metbo_0688
symbol: ADZ08939.1
gene_biotype: protein_coding
description:
  Methanogenesis marker protein 15; KEGG: mth:MTH1869 activator of (R)-2-hydroxyglutaryl-CoA; TIGRFAM: Putative methanogenesis marker protein 15; CoA enzyme activase; PFAM: ATPase, BadF/BadG/BcrA/BcrD type.


ensembl_gene_id: Metbo_0689
symbol: ADZ08940.1
gene_biotype: protein_coding
description:
  Methanogenesis marker protein 17; KEGG: mth:MTH1870 hypothetical protein; TIGRFAM: Uncharacterised conserved protein UCP019464, methanogenesis; PFAM: Uncharacterised conserved protein UCP019464, methanogenesis.


ensembl_gene_id: Metbo_0690
symbol: ADZ08941.1
gene_biotype: protein_coding
description:
  Radical SAM domain protein; KEGG: mth:MTH1871 nitrogenase iron-molybdenum cofactor biosynthesis protein NifB; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB.


ensembl_gene_id: Metbo_0691
symbol: ADZ08942.1
gene_biotype: protein_coding
description:
  Translation initiation factor, aIF-2BI family; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.


ensembl_gene_id: Metbo_0693
symbol: dphB
gene_biotype: protein_coding
description:
  Diphthine synthase; S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis.


ensembl_gene_id: Metbo_0694
symbol: ADZ08945.1
gene_biotype: protein_coding
description:
  DNA adenine methylase; Manually curated; TIGRFAM: D12 class N6 adenine-specific DNA methyltransferase; KEGG: tit:Thit_0485 DNA adenine methylase; PFAM: D12 class N6 adenine-specific DNA methyltransferase.


ensembl_gene_id: Metbo_0696
symbol: ADZ08947.1
gene_biotype: protein_coding
description:
  Sulfate-transporting ATPase; PFAM: ABC transporter-like; KEGG: msi:Msm_1483 multidrug ABC transporter, ATPase component; SMART: ATPase, AAA+ type, core.


ensembl_gene_id: Metbo_0699
symbol: ADZ08950.1
gene_biotype: protein_coding
description:
  PFAM: Queuine/other tRNA-ribosyltransferase; KEGG: mru:mru_0814 archaeosine tRNA-ribosyltransferase TgtA1.


ensembl_gene_id: Metbo_0700
symbol: ADZ08951.1
gene_biotype: protein_coding
description:
  KEGG: mth:MTH1878 heterodisulfide reductase, subunit C; TIGRFAM: CoB--CoM heterodisulphide reductase, subunit C.


ensembl_gene_id: Metbo_0701
symbol: ADZ08952.1
gene_biotype: protein_coding
description:
  TIGRFAM: CoB--CoM heterodisulphide reductase, subunit B; KEGG: mmg:MTBMA_c04500 CoB-CoM heterodisulfide reductase, subunit B; PFAM: Cysteine-rich domain.


ensembl_gene_id: Metbo_0704
symbol: ADZ08955.1
gene_biotype: protein_coding
description:
  Metallophosphoesterase; PFAM: Metallo-dependent phosphatase; KEGG: mth:MTH1882 hypothetical protein.


ensembl_gene_id: Metbo_0706
symbol: ADZ08957.1
gene_biotype: protein_coding
description:
  KEGG: mfv:Mfer_0246 signal transduction protein with cbs domains; PFAM: Cystathionine beta-synthase, core; SMART: Cystathionine beta-synthase, core.


ensembl_gene_id: Metbo_0710
symbol: ADZ08961.1
gene_biotype: protein_coding
description:
  HhH-GPD family protein; KEGG: mac:MA3207 DNA-3-methyladenine glycosylase II; PFAM: HhH-GPD domain; SMART: HhH-GPD domain.


ensembl_gene_id: Metbo_0711
symbol: ADZ08962.1
gene_biotype: protein_coding
description:
  Putative transcriptional regulator, GntR family; KEGG: rci:RRC4 putative aminotransferase; PFAM: Aminotransferase, class I/classII.


ensembl_gene_id: Metbo_0712
symbol: ADZ08963.1
gene_biotype: protein_coding
description:
  PFAM: 4Fe-4S binding domain; KEGG: mbn:Mboo_1630 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein.


ensembl_gene_id: Metbo_0715
symbol: ADZ08966.1
gene_biotype: protein_coding
description:
  KEGG: mfv:Mfer_0025 radical sam domain protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB.


ensembl_gene_id: Metbo_0717
symbol: coaD
gene_biotype: protein_coding
description:
  Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the eukaryotic CoaD family.


ensembl_gene_id: Metbo_0718
symbol: ADZ08969.1
gene_biotype: protein_coding
description:
  UPF0244 protein yjjX; Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.


ensembl_gene_id: Metbo_0719
symbol: ADZ08970.1
gene_biotype: protein_coding
description:
  PFAM: Oligosaccharyl transferase, STT3 subunit; KEGG: mth:MTH1623 oligosaccharyl transferase STT3 subunit related protein.


ensembl_gene_id: Metbo_0724
symbol: ADZ08975.1
gene_biotype: protein_coding
description:
  KEGG: pmx:PERMA_1747 UDP-glucuronic acid decarboxylase 1 (UDP-glucuronatedecarboxylase 1) (UXS-1); PFAM: NAD-dependent epimerase/dehydratase.


ensembl_gene_id: Metbo_0728
symbol: ADZ08979.1
gene_biotype: protein_coding
description:
  PFAM: Bacterial transferase hexapeptide repeat; KEGG: mfv:Mfer_0757 acetyl / acyl transferase related protein.


ensembl_gene_id: Metbo_0730
symbol: ADZ08981.1
gene_biotype: protein_coding
description:
  Hypothetical protein; PFAM: Class III signal peptide motif; KEGG: mmg:MTBMA_c04690 hypothetical protein.


ensembl_gene_id: Metbo_0734
symbol: ADZ08985.1
gene_biotype: protein_coding
description:
  Glycosyltransferase 28 domain protein; PFAM: Glycosyl transferase, family 28, C-terminal; KEGG: mst:Msp_0515 hypothetical protein.


ensembl_gene_id: Metbo_0736
symbol: ADZ08987.1
gene_biotype: protein_coding
description:
  HAMAP: Uncharacterised protein family UPF0173, metal-dependent hydrolase; PFAM: Beta-lactamase-like; KEGG: mru:mru_0834 metallo-beta-lactamase superfamily protein; SMART: Beta-lactamase-like; Belongs to the UPF0173 family.


ensembl_gene_id: Metbo_0739
symbol: ADZ08990.1
gene_biotype: protein_coding
description:
  PFAM: Protein of unknown function DUF2072, Zinc-ribbon; KEGG: mmg:MTBMA_c04770 hypothetical protein.


ensembl_gene_id: Metbo_0740
symbol: ADZ08991.1
gene_biotype: protein_coding
description:
  PFAM: Fibronectin-binding A, N-terminal; Domain of unknown function DUF814; KEGG: mmg:MTBMA_c04780 hypothetical protein.


ensembl_gene_id: Metbo_0744
symbol: ADZ08995.1
gene_biotype: protein_coding
description:
  TIGRFAM: Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain; KEGG: mst:Msp_0791 fumarate hydratase; PFAM: Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain.


ensembl_gene_id: Metbo_0747
symbol: ADZ08998.1
gene_biotype: protein_coding
description:
  KEGG: mth:MTH447 sensory transduction regulatory protein; PFAM: Signal transduction response regulator, receiver domain; SMART: Signal transduction response regulator, receiver domain.


ensembl_gene_id: Metbo_0748
symbol: ADZ08999.1
gene_biotype: protein_coding
description:
  KEGG: mmg:MTBMA_c11120 tetratricopeptide repeat domain-containing protein; PFAM: Tetratricopeptide TPR-1; Tetratricopeptide TPR2; SMART: Tetratricopeptide repeat.


ensembl_gene_id: Metbo_0749
symbol: ADZ09000.1
gene_biotype: protein_coding
description:
  Cation diffusion facilitator family transporter; KEGG: taf:THA_291 cation efflux family protein; TIGRFAM: Cation efflux protein; PFAM: Cation efflux protein.


ensembl_gene_id: Metbo_0752
symbol: cbiM
gene_biotype: protein_coding
description:
  Cobalamin biosynthesis protein CbiM; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.


ensembl_gene_id: Metbo_0753
symbol: cbiN
gene_biotype: protein_coding
description:
  Cobalt transport protein; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import; Belongs to the CbiN family.


ensembl_gene_id: Metbo_0754
symbol: ADZ09005.1
gene_biotype: protein_coding
description:
  KEGG: mfv:Mfer_0953 cobalt abc transporter, inner membrane subunit CbiQ; TIGRFAM: Cobalt ABC transporter CbiQ, permease subunit; PFAM: Cobalt transport protein.


ensembl_gene_id: Metbo_0757
symbol: ADZ09008.1
gene_biotype: protein_coding
description:
  TIGRFAM: PAS; PFAM: Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain; Signal transduction response regulator, receiver domain; PAS fold-3; PAS fold; PAS fold-4; ATPase-like, ATP-binding domain; KEGG: cyb:CYB_1653 sensory box histidine kinase; SMART: Signal transduction response regulator, receiver domain; PAS; PAC motif; ATPase-like, ATP-binding domain.


ensembl_gene_id: Metbo_0759
symbol: ADZ09010.1
gene_biotype: protein_coding
description:
  Protein of unknown function DUF88; KEGG: mmg:MTBMA_c04840 hypothetical protein; TIGRFAM: Conserved hypothetical protein CHP00288; PFAM: Domain of unknown function DUF88.


ensembl_gene_id: Metbo_0760
symbol: ADZ09011.1
gene_biotype: protein_coding
description:
  TIGRFAM: Pyridoxal phosphate-dependent transferase, archaea; KEGG: msi:Msm_0767 selenocysteine synthase, SelA.


ensembl_gene_id: Metbo_0761
symbol: rtcA
gene_biotype: protein_coding
description:
  RNA 3'-terminal phosphate cyclase; Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.


ensembl_gene_id: Metbo_0762
symbol: ADZ09013.1
gene_biotype: protein_coding
description:
  LmbE family protein; PFAM: N-acetylglucosaminyl phosphatidylinositol deacetylase; KEGG: mfv:Mfer_0717 LmbE family protein.


ensembl_gene_id: Metbo_0763
symbol: ADZ09014.1
gene_biotype: protein_coding
description:
  TIGRFAM: Biotin--acetyl-CoA-carboxylase ligase; KEGG: mmg:MTBMA_c04870 biotin ligase; PFAM: Biotin/lipoate A/B protein ligase; Biotin protein ligase, C-terminal.


ensembl_gene_id: Metbo_0764
symbol: ADZ09015.1
gene_biotype: protein_coding
description:
  SMART: Biotin carboxylase, C-terminal; TIGRFAM: Acetyl-CoA carboxylase, biotin carboxylase; KEGG: mmg:MTBMA_c04880 pyruvate carboxylase, subunit A; PFAM: Carbamoyl-phosphate synthetase, large subunit, ATP-binding; Carbamoyl-phosphate synthase, large subunit, N-terminal; Biotin carboxylase, C-terminal.


ensembl_gene_id: Metbo_0765
symbol: ADZ09016.1
gene_biotype: protein_coding
description:
  PFAM: Methyltransferase type 11; KEGG: msi:Msm_0764 ribosomal L11 RNA methyltransferase (SAM-dependent).


ensembl_gene_id: Metbo_0774
symbol: rpl3
gene_biotype: protein_coding
description:
  Ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.


ensembl_gene_id: Metbo_0776
symbol: rpl23
gene_biotype: protein_coding
description:
  Ribosomal protein L23; Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family.


ensembl_gene_id: Metbo_0777
symbol: rpl2
gene_biotype: protein_coding
description:
  Ribosomal protein L2, C-terminal; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.


ensembl_gene_id: Metbo_0778
symbol: rps19p
gene_biotype: protein_coding
description:
  Ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.


ensembl_gene_id: Metbo_0779
symbol: rpl22
gene_biotype: protein_coding
description:
  Ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.


ensembl_gene_id: Metbo_0780
symbol: rps3
gene_biotype: protein_coding
description:
  Ribosomal protein S3; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family.


ensembl_gene_id: Metbo_0781
symbol: rpl29
gene_biotype: protein_coding
description:
  KEGG: msi:Msm_0755 50S ribosomal protein L29P; TIGRFAM: Ribosomal protein L29; PFAM: Ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family.


ensembl_gene_id: Metbo_0782
symbol: ADZ09033.1
gene_biotype: protein_coding
description:
  TIGRFAM: Archaeal/bacterial translation initiation factor SUI1; HAMAP: Translation factor SUI1 homolog, archaea; KEGG: mru:mru_0859 translation initiation factor aSUI1; PFAM: Translation initiation factor SUI1; Belongs to the SUI1 family.


ensembl_gene_id: Metbo_0783
symbol: rnp1
gene_biotype: protein_coding
description:
  Ribonuclease P protein component 1; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 1 family.


ensembl_gene_id: Metbo_0784
symbol: rps17
gene_biotype: protein_coding
description:
  Ribosomal protein S17P; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.


ensembl_gene_id: Metbo_0785
symbol: rpl14
gene_biotype: protein_coding
description:
  50S ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.


ensembl_gene_id: Metbo_0787
symbol: rps4e
gene_biotype: protein_coding
description:
  HAMAP: Ribosomal protein S4e, archaea; PFAM: Ribosomal protein S4e, central; Ribosomal protein S4e, N-terminal; RNA-binding S4; KEGG: mmg:MTBMA_c05040 30S ribosomal protein S4e; SMART: RNA-binding S4; Belongs to the eukaryotic ribosomal protein eS4 family.


ensembl_gene_id: Metbo_0788
symbol: rpl5
gene_biotype: protein_coding
description:
  Ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.


ensembl_gene_id: Metbo_0790
symbol: rps8
gene_biotype: protein_coding
description:
  Ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.


ensembl_gene_id: Metbo_0791
symbol: rpl6
gene_biotype: protein_coding
description:
  Ribosomal protein L6P; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.


ensembl_gene_id: Metbo_0793
symbol: rpl19e
gene_biotype: protein_coding
description:
  Ribosomal protein L19e; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family.


ensembl_gene_id: Metbo_0794
symbol: rpl18
gene_biotype: protein_coding
description:
  Ribosomal protein L18P/L5E; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.


ensembl_gene_id: Metbo_0796
symbol: rpl30
gene_biotype: protein_coding
description:
  KEGG: mmg:MTBMA_c05130 50S ribosomal protein L30P; TIGRFAM: Ribosomal protein L30, archaeal; PFAM: Ribosomal protein L30, ferredoxin-like fold domain.


ensembl_gene_id: Metbo_0797
symbol: rpl15
gene_biotype: protein_coding
description:
  50S ribosomal protein L15P; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.


ensembl_gene_id: Metbo_0798
symbol: secY
gene_biotype: protein_coding
description:
  Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.


ensembl_gene_id: Metbo_0799
symbol: adkA
gene_biotype: protein_coding
description:
  KEGG: msi:Msm_0737 adenylate kinase; HAMAP: Adenylate kinase; Belongs to the archaeal adenylate kinase family.


ensembl_gene_id: Metbo_0800
symbol: ADZ09051.1
gene_biotype: protein_coding
description:
  PFAM: Protein of unknown function DUF106, transmembrane; KEGG: mmg:MTBMA_c05170 hypothetical protein.


ensembl_gene_id: Metbo_0801
symbol: rpl34e
gene_biotype: protein_coding
description:
  KEGG: mmg:MTBMA_c05180 50S ribosomal protein L34E; HAMAP: 50S ribosomal protein L34e; PFAM: Ribosomal protein L34e; Belongs to the eukaryotic ribosomal protein eL34 family.


ensembl_gene_id: Metbo_0802
symbol: cmk
gene_biotype: protein_coding
description:
  KEGG: msi:Msm_0734 cytidylate kinase; TIGRFAM: Cytidylate kinase, putative; HAMAP: Cytidylate kinase, putative.


ensembl_gene_id: Metbo_0804
symbol: truB
gene_biotype: protein_coding
description:
  tRNA pseudouridine synthase B; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.


ensembl_gene_id: Metbo_0805
symbol: rps13
gene_biotype: protein_coding
description:
  Ribosomal protein S13P; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement; Belongs to the universal ribosomal protein uS13 family.


ensembl_gene_id: Metbo_0806
symbol: rps4
gene_biotype: protein_coding
description:
  Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.


ensembl_gene_id: Metbo_0807
symbol: rps11
gene_biotype: protein_coding
description:
  Ribosomal protein S11P; Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family.


ensembl_gene_id: Metbo_0808
symbol: rpoD
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase subunit D; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: Metbo_0809
symbol: rpl18e
gene_biotype: protein_coding
description:
  HAMAP: Ribosomal protein L18e, archaea; KEGG: msi:Msm_1429 50S ribosomal protein L18e; Belongs to the eukaryotic ribosomal protein eL18 family.


ensembl_gene_id: Metbo_0810
symbol: rpl13
gene_biotype: protein_coding
description:
  Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.


ensembl_gene_id: Metbo_0811
symbol: rps9
gene_biotype: protein_coding
description:
  KEGG: mth:MTH39 ribosomal protein S16; TIGRFAM: Ribosomal protein S9, archaeal; PFAM: Ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.


ensembl_gene_id: Metbo_0812
symbol: ADZ09063.1
gene_biotype: protein_coding
description:
  PFAM: RNA polymerases, N/8kDa subunit; KEGG: mmg:MTBMA_c05305 DNA-directed RNA polymerase subunit N.


ensembl_gene_id: Metbo_0813
symbol: rpoK
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase subunit K; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit family.


ensembl_gene_id: Metbo_0814
symbol: eno
gene_biotype: protein_coding
description:
  Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.


ensembl_gene_id: Metbo_0815
symbol: ADZ09066.1
gene_biotype: protein_coding
description:
  PFAM: 4Fe-4S binding domain; KEGG: mfv:Mfer_0637 4fe-4S ferredoxin iron-sulfur binding domain protein.


ensembl_gene_id: Metbo_0816
symbol: rps2
gene_biotype: protein_coding
description:
  KEGG: mth:MTH44 30S ribosomal protein S2; TIGRFAM: Ribosomal protein S2, eukaryotic/archaeal; PFAM: Ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.


ensembl_gene_id: Metbo_0817
symbol: ADZ09068.1
gene_biotype: protein_coding
description:
  UPF0103 protein; KEGG: mfv:Mfer_0894 hypothetical protein; HAMAP: Uncharacterised protein family UPF0103; PFAM: UPF0103/Mediator of ErbB2-driven cell motility (Memo-related); Belongs to the MEMO1 family.


ensembl_gene_id: Metbo_0818
symbol: mvk
gene_biotype: protein_coding
description:
  Mevalonate kinase; Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)- mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. Mevalonate kinase subfamily.


ensembl_gene_id: Metbo_0819
symbol: ADZ09070.1
gene_biotype: protein_coding
description:
  Aspartate/glutamate/uridylate kinase; Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids.


ensembl_gene_id: Metbo_0820
symbol: fni
gene_biotype: protein_coding
description:
  Isopentenyl-diphosphate delta-isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).


ensembl_gene_id: Metbo_0821
symbol: rnj
gene_biotype: protein_coding
description:
  Beta-lactamase domain protein; An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation; Belongs to the metallo-beta-lactamase superfamily. RNA- metabolizing metallo-beta-lactamase-like family. Archaeal RNase J subfamily.


ensembl_gene_id: Metbo_0822
symbol: ADZ09073.1
gene_biotype: protein_coding
description:
  Dimethylallyltranstransferase; KEGG: mth:MTH50 bifunctional short chain isoprenyl diphosphate synthase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.


ensembl_gene_id: Metbo_0823
symbol: gltX
gene_biotype: protein_coding
description:
  glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).


ensembl_gene_id: Metbo_0824
symbol: dapL
gene_biotype: protein_coding
description:
  LL-diaminopimelate aminotransferase; Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL- diaminopimelate.


ensembl_gene_id: Metbo_0828
symbol: ADZ09079.1
gene_biotype: protein_coding
description:
  Regulatory protein MarR; KEGG: mmg:MTBMA_c13170 transcriptional regulator; PFAM: HTH transcriptional regulator, MarR; SMART: HTH transcriptional regulator, MarR.


ensembl_gene_id: Metbo_0831
symbol: purA
gene_biotype: protein_coding
description:
  Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.


ensembl_gene_id: Metbo_0836
symbol: ADZ09086.1
gene_biotype: protein_coding
description:
  Precorrin-4 C11-methyltransferase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobM/CbiF, precorrin-4 C11-methyltransferase, core; KEGG: msi:Msm_0101 precorrin-3 methylase, CbiF; PFAM: Tetrapyrrole methylase.


ensembl_gene_id: Metbo_0837
symbol: ADZ09087.1
gene_biotype: protein_coding
description:
  PFAM: Protein of unknown function DUF166; 4Fe-4S binding domain; KEGG: mmp:MMP0986 thymidylate synthase.


ensembl_gene_id: Metbo_0838
symbol: ADZ09088.1
gene_biotype: protein_coding
description:
  Response regulator receiver protein; KEGG: mth:MTH374 dolichyl-phosphate mannose synthase related protein; PFAM: Glycosyl transferase, family 2; Signal transduction response regulator, receiver domain; SMART: Signal transduction response regulator, receiver domain.


ensembl_gene_id: Metbo_0839
symbol: ADZ09089.1
gene_biotype: protein_coding
description:
  GDP-mannose 4,6-dehydratase; KEGG: mst:Msp_0990 GDP-D-mannose dehydratase; PFAM: NAD-dependent epimerase/dehydratase.


ensembl_gene_id: Metbo_0840
symbol: ADZ09090.1
gene_biotype: protein_coding
description:
  Abortive infection protein; KEGG: mth:MTH633 hypothetical protein; PFAM: Abortive infection protein; Tetratricopeptide TPR2; Tetratricopeptide TPR-1; SMART: Tetratricopeptide repeat.


ensembl_gene_id: Metbo_0848
symbol: ADZ09098.1
gene_biotype: protein_coding
description:
  Conserved repeat domain protein; TIGRFAM: Domain of unknown function DUF11; PFAM: Bacterial Ig-like, group 1; Domain of unknown function DUF11; KEGG: fjo:Fjoh_3971 hypothetical protein; SMART: Bacterial Ig-like, group 1.


ensembl_gene_id: Metbo_0851
symbol: ADZ09101.1
gene_biotype: protein_coding
description:
  Xenobiotic-transporting ATPase; PFAM: ABC transporter-like; KEGG: sfu:Sfum_3988 ABC transporter related; SMART: ATPase, AAA+ type, core.


ensembl_gene_id: Metbo_0854
symbol: ADZ09104.1
gene_biotype: protein_coding
description:
  PFAM: Glycosyl transferase, family 2; KEGG: has:Halsa_0644 undecaprenyl-phosphate galactose phosphotransferase.


ensembl_gene_id: Metbo_0863
symbol: ADZ09113.1
gene_biotype: protein_coding
description:
  PFAM: Coenzyme F420 hydrogenase/dehydrogenase beta subunit, C-terminal; Coenzyme F420 hydrogenase/dehydrogenase beta subunit, N-terminal; 4Fe-4S binding domain; KEGG: mth:MTH341 coenzyme F420-reducing hydrogenase, beta subunit-like protein.


ensembl_gene_id: Metbo_0864
symbol: ADZ09114.1
gene_biotype: protein_coding
description:
  PFAM: Polysaccharide biosynthesis protein; KEGG: mth:MTH342 succinoglycan biosynthesis transport protein.


ensembl_gene_id: Metbo_0866
symbol: ADZ09116.1
gene_biotype: protein_coding
description:
  TIGRFAM: Nucleotide sugar dehydrogenase; KEGG: mpl:Mpal_0929 nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase, N-terminal; UDP-glucose/GDP-mannose dehydrogenase, dimerisation; UDP-glucose/GDP-mannose dehydrogenase, C-terminal; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.


ensembl_gene_id: Metbo_0874
symbol: ADZ09123.1
gene_biotype: protein_coding
description:
  Parallel beta-helix repeat; KEGG: mth:MTH1074 hypothetical protein; TIGRFAM: Parallel beta-helix repeat-2; Domain of unknown function DUF11; PFAM: Domain of unknown function DUF11.


ensembl_gene_id: Metbo_0880
symbol: ADZ09129.1
gene_biotype: protein_coding
description:
  KEGG: cpr:CPR_0493 MarR family transcriptional regulator; PFAM: HTH transcriptional regulator, MarR; SMART: HTH transcriptional regulator, MarR.


ensembl_gene_id: Metbo_0884
symbol: ADZ09133.1
gene_biotype: protein_coding
description:
  PFAM: UbiA prenyltransferase; KEGG: pto:PTO0182 (S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase.


ensembl_gene_id: Metbo_0887
symbol: ADZ09136.1
gene_biotype: protein_coding
description:
  PFAM: Polysaccharide biosynthesis protein; KEGG: pho:PH0421 lipopolysaccharide O-side chain biosynthesis protein (O-antigen transporter).


ensembl_gene_id: Metbo_0891
symbol: ADZ09140.1
gene_biotype: protein_coding
description:
  PFAM: Protein of unknown function DUF2206, membrane; KEGG: mpl:Mpal_1995 membrane protein-like protein.


ensembl_gene_id: Metbo_0893
symbol: ADZ09142.1
gene_biotype: protein_coding
description:
  PFAM: Domain of unknown function DUF1972; Glycosyl transferase, group 1; KEGG: llc:LACR_0206 glycosyltransferase.


ensembl_gene_id: Metbo_0894
symbol: ADZ09143.1
gene_biotype: protein_coding
description:
  KEGG: mru:mru_1246 adhesin-like protein; TIGRFAM: Domain of unknown function DUF11; PFAM: Polysaccharide deacetylase.


ensembl_gene_id: Metbo_0897
symbol: ADZ09146.1
gene_biotype: protein_coding
description:
  TIGRFAM: Undecaprenyl-phosphate glucose phosphotransferase, WcaJ; Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; KEGG: msi:Msm_1331 sugar transferase, WcaJ; PFAM: Bacterial sugar transferase.


ensembl_gene_id: Metbo_0901
symbol: ADZ09150.1
gene_biotype: protein_coding
description:
  Teichoic-acid-transporting ATPase; PFAM: ABC transporter-like; KEGG: mst:Msp_0205 polysaccharide/polyol phosphate ABC transporter ATP-binding protein; SMART: ATPase, AAA+ type, core.


ensembl_gene_id: Metbo_0902
symbol: ADZ09151.1
gene_biotype: protein_coding
description:
  PFAM: ABC-2 type transporter; KEGG: mst:Msp_0204 polysaccharide/polyol phosphate ABC transporter permease.


ensembl_gene_id: Metbo_0903
symbol: ADZ09152.1
gene_biotype: protein_coding
description:
  TIGRFAM: Nucleotide sugar dehydrogenase; KEGG: mst:Msp_0210 UDP-glucose 6-dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase, N-terminal; UDP-glucose/GDP-mannose dehydrogenase, dimerisation; UDP-glucose/GDP-mannose dehydrogenase, C-terminal.


ensembl_gene_id: Metbo_0904
symbol: ADZ09153.1
gene_biotype: protein_coding
description:
  dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.


ensembl_gene_id: Metbo_0912
symbol: ADZ09161.1
gene_biotype: protein_coding
description:
  TIGRFAM: Nucleotide sugar dehydrogenase; KEGG: mth:MTH836 UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase, N-terminal; UDP-glucose/GDP-mannose dehydrogenase, dimerisation; UDP-glucose/GDP-mannose dehydrogenase, C-terminal; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.


ensembl_gene_id: Metbo_0919
symbol: ADZ09168.1
gene_biotype: protein_coding
description:
  TIGRFAM: Glucose-1-phosphate thymidylyltransferase, long form; KEGG: mth:MTH1791 glucose-1-phosphate thymidylyltransferase; PFAM: Nucleotidyl transferase.


ensembl_gene_id: Metbo_0920
symbol: ADZ09169.1
gene_biotype: protein_coding
description:
  TIGRFAM: dTDP-4-dehydrorhamnose reductase; KEGG: mfv:Mfer_0285 dTDP-4-dehydrorhamnose reductase; PFAM: dTDP-4-dehydrorhamnose reductase.


ensembl_gene_id: Metbo_0921
symbol: ADZ09170.1
gene_biotype: protein_coding
description:
  KEGG: mfv:Mfer_0117 polymorphic outer membrane protein; TIGRFAM: Polymorphic membrane protein, Chlamydia; PFAM: Polymorphic membrane protein, Chlamydia.


ensembl_gene_id: Metbo_0927
symbol: ADZ09175.1
gene_biotype: protein_coding
description:
  KEGG: mmg:MTBMA_c12420 transglutaminase related protein; PFAM: Transglutaminase-like; SMART: Transglutaminase-like.


ensembl_gene_id: Metbo_0931
symbol: ADZ09178.1
gene_biotype: protein_coding
description:
  Peptidase C1A papain; KEGG: mac:MA1513 hypothetical protein; PFAM: Peptidase C1A, papain C-terminal; SMART: Peptidase C1A, papain C-terminal.


ensembl_gene_id: Metbo_0932
symbol: ADZ09179.1
gene_biotype: protein_coding
description:
  Polymorphic outer membrane protein; KEGG: mmg:MTBMA_c06050 pseudomurein-binding protein; TIGRFAM: Polymorphic membrane protein, Chlamydia; PFAM: ORF3b coronavirus protein; Polymorphic membrane protein, Chlamydia.


ensembl_gene_id: Metbo_0935
symbol: ADZ09182.1
gene_biotype: protein_coding
description:
  Desulfoferrodoxin; KEGG: mmg:MTBMA_c11510 superoxide reductase; TIGRFAM: Desulfoferrodoxin; Desulfoferrodoxin Dfx; Desulfoferrodoxin, ferrous iron-binding domain; PFAM: Desulfoferrodoxin, ferrous iron-binding domain; Desulfoferrodoxin Dfx.


ensembl_gene_id: Metbo_0937
symbol: ADZ09184.1
gene_biotype: protein_coding
description:
  TIGRFAM: PAS; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS fold-3; PAS fold; KEGG: mac:MA1270 sensory transduction histidine kinase; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS; PAC motif.


ensembl_gene_id: Metbo_0939
symbol: ADZ09186.1
gene_biotype: protein_coding
description:
  Phosphoesterase RecJ domain protein; KEGG: mmg:MTBMA_c11580 archaea-specific RecJ-like exonuclease; PFAM: Phosphoesterase, RecJ-like; Nucleic acid binding, OB-fold, tRNA/helicase-type; Ribosomal protein S1, RNA-binding domain; SMART: RNA-binding domain, S1.


ensembl_gene_id: Metbo_0940
symbol: nth
gene_biotype: protein_coding
description:
  DNA-(apurinic or apyrimidinic site) lyase; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.


ensembl_gene_id: Metbo_0941
symbol: ADZ09188.1
gene_biotype: protein_coding
description:
  TIGRFAM: Small GTP-binding protein; PFAM: Mitochondrial Rho-like; KEGG: mth:MTH765 GTP-binding protein Rab related protein; SMART: Ras small GTPase, Ras type.


ensembl_gene_id: Metbo_0942
symbol: aroA
gene_biotype: protein_coding
description:
  3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.


ensembl_gene_id: Metbo_0943
symbol: valS
gene_biotype: protein_coding
description:
  Valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.


ensembl_gene_id: Metbo_0945
symbol: ADZ09192.1
gene_biotype: protein_coding
description:
  PFAM: Heat shock protein Hsp20; KEGG: mmg:MTBMA_c12560 small heat shock protein; Belongs to the small heat shock protein (HSP20) family.


ensembl_gene_id: Metbo_0950
symbol: pheT
gene_biotype: protein_coding
description:
  Phenylalanyl-tRNA synthetase beta chain; SMART: B3/B4 tRNA-binding domain; tRNA synthetase, B5; TIGRFAM: Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archae/euk cytosolic; KEGG: mmg:MTBMA_c11660 phenylalanyl-tRNA synthetase, beta chain; HAMAP: Phenylalanyl-tRNA synthetase beta chain 2, bacterial/archaeal; PFAM: tRNA synthetase, B5; B3/B4 tRNA-binding domain.


ensembl_gene_id: Metbo_0951
symbol: ADZ09198.1
gene_biotype: protein_coding
description:
  KEGG: apo:Arcpr_0384 protein of unknown function UPF0047; TIGRFAM: Uncharacterised protein family UPF0047; PFAM: Uncharacterised protein family UPF0047.


ensembl_gene_id: Metbo_0952
symbol: pyrI
gene_biotype: protein_coding
description:
  Aspartate carbamoyltransferase regulatory chain; Involved in allosteric regulation of aspartate carbamoyltransferase.


ensembl_gene_id: Metbo_0953
symbol: ADZ09200.1
gene_biotype: protein_coding
description:
  Na+/Ca+ antiporter, CaCA family; KEGG: mth:MTH1155 Na+/Ca+ exchanging protein related; TIGRFAM: K+-dependent Na+/Ca+ exchanger-like; PFAM: Sodium/calcium exchanger membrane region.


ensembl_gene_id: Metbo_0957
symbol: argC
gene_biotype: protein_coding
description:
  N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.


ensembl_gene_id: Metbo_0959
symbol: argB
gene_biotype: protein_coding
description:
  Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.


ensembl_gene_id: Metbo_0960
symbol: argJ
gene_biotype: protein_coding
description:
  Arginine biosynthesis bifunctional protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.


ensembl_gene_id: Metbo_0964
symbol: ADZ09211.1
gene_biotype: protein_coding
description:
  Metallophosphoesterase; PFAM: Metallo-dependent phosphatase; KEGG: mmg:MTBMA_c06310 phosphohydrolase.


ensembl_gene_id: Metbo_0965
symbol: nac
gene_biotype: protein_coding
description:
  Nascent polypeptide-associated complex protein; Contacts the emerging nascent chain on the ribosome. Belongs to the NAC-alpha family.


ensembl_gene_id: Metbo_0966
symbol: tgtA
gene_biotype: protein_coding
description:
  7-cyano-7-deazaguanine tRNA-ribosyltransferase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family.


ensembl_gene_id: Metbo_0978
symbol: ADZ09225.1
gene_biotype: protein_coding
description:
  Lactate utilization protein B/C; PFAM: Domain of unknown function DUF162; KEGG: mmg:MTBMA_c05900 conserved iron-sulfur cluster binding protein.


ensembl_gene_id: Metbo_0980
symbol: ADZ09227.1
gene_biotype: protein_coding
description:
  PFAM: Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain; KEGG: pth:PTH_0218 hypothetical protein.


ensembl_gene_id: Metbo_0982
symbol: mfnB
gene_biotype: protein_coding
description:
  UPF0264 protein; Catalyzes the formation of 4-(hydroxymethyl)-2- furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P).


ensembl_gene_id: Metbo_0983
symbol: guaB
gene_biotype: protein_coding
description:
  Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.


ensembl_gene_id: Metbo_0984
symbol: mobA
gene_biotype: protein_coding
description:
  Molybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.


ensembl_gene_id: Metbo_0988
symbol: cbiT
gene_biotype: protein_coding
description:
  cobalt-precorrin-6Y C(15)-methyltransferase (decarboxylating); Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin-7.


ensembl_gene_id: Metbo_0989
symbol: ubiX
gene_biotype: protein_coding
description:
  3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family.


ensembl_gene_id: Metbo_0990
symbol: ADZ09237.1
gene_biotype: protein_coding
description:
  KEGG: mth:MTH148 hypothetical protein; PFAM: Metal-dependent phosphohydrolase, HD subdomain; SMART: Metal-dependent phosphohydrolase, HD domain.


ensembl_gene_id: Metbo_0991
symbol: ADZ09238.1
gene_biotype: protein_coding
description:
  PFAM: Molybdopterin biosynthesis MoaE; KEGG: mru:mru_1268 molybdenum cofactor biosynthesis protein MoaE.


ensembl_gene_id: Metbo_0992
symbol: ADZ09239.1
gene_biotype: protein_coding
description:
  PFAM: Cytidylyltransferase; TIGRFAM: Nicotinamide-nucleotide adenylyltransferase, archaeal type; Cytidyltransferase-related; HAMAP: Nicotinamide-nucleotide adenylyltransferase, archaeal type; KEGG: mmg:MTBMA_c06000 nicotinamide-nucleotide adenylyltransferase.


ensembl_gene_id: Metbo_0995
symbol: ADZ09242.1
gene_biotype: protein_coding
description:
  ABC transporter related protein; KEGG: mmg:MTBMA_c06010 methyl-coenzyme M reductase component A2-like protein; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core.


ensembl_gene_id: Metbo_0999
symbol: ADZ09246.1
gene_biotype: protein_coding
description:
  Rubredoxin-type Fe(Cys)4 protein; Rubredoxin is a small nonheme, iron protein lacking acid- labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule.


ensembl_gene_id: Metbo_1003
symbol: ADZ09250.1
gene_biotype: protein_coding
description:
  Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.


ensembl_gene_id: Metbo_1004
symbol: ADZ09251.1
gene_biotype: protein_coding
description:
  Manganese/iron superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.


ensembl_gene_id: Metbo_1008
symbol: ADZ09255.1
gene_biotype: protein_coding
description:
  Phenylacetate--CoA ligase; KEGG: mmg:MTBMA_c04250 coenzyme F390 synthetase; PFAM: AMP-dependent synthetase/ligase.


ensembl_gene_id: Metbo_1011
symbol: ADZ09258.1
gene_biotype: protein_coding
description:
  TIGRFAM: Phosphomethylpyrimidine kinase type-2; KEGG: mfv:Mfer_1038 phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1.


ensembl_gene_id: Metbo_1012
symbol: cofC
gene_biotype: protein_coding
description:
  2-phospho-L-lactate guanylyltransferase CofC; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family.


ensembl_gene_id: Metbo_1014
symbol: proS
gene_biotype: protein_coding
description:
  Prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).


ensembl_gene_id: Metbo_1015
symbol: egsA
gene_biotype: protein_coding
description:
  3-dehydroquinate synthase; Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea.


ensembl_gene_id: Metbo_1017
symbol: ADZ09264.1
gene_biotype: protein_coding
description:
  UPF0179 protein; KEGG: mmg:MTBMA_c09890 hypothetical protein; HAMAP: Uncharacterised protein family UPF0179; PFAM: Uncharacterised protein family UPF0179; Belongs to the UPF0179 family.


ensembl_gene_id: Metbo_1018
symbol: rpiA
gene_biotype: protein_coding
description:
  Ribose-5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.


ensembl_gene_id: Metbo_1020
symbol: ADZ09267.1
gene_biotype: protein_coding
description:
  Transcriptional regulator, ArsR family; KEGG: mmg:MTBMA_c17390 transcriptional regulator; PFAM: 4-vinyl reductase, 4VR; HTH transcriptional regulator, ArsR; SMART: HTH transcriptional regulator, ArsR.


ensembl_gene_id: Metbo_1021
symbol: ADZ09268.1
gene_biotype: protein_coding
description:
  4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; PFAM: 4Fe-4S binding domain; KEGG: mst:Msp_0190 MapA.


ensembl_gene_id: Metbo_1022
symbol: ADZ09269.1
gene_biotype: protein_coding
description:
  Cobalamin B12-binding domain protein; PFAM: Cobalamin (vitamin B12)-binding; Methionine synthase, cobalamin (vitamin B12)-binding module, cap; KEGG: msi:Msm_0516 corrinoid protein (methionine synthase-related), MtaC.


ensembl_gene_id: Metbo_1025
symbol: ADZ09272.1
gene_biotype: protein_coding
description:
  Methyltransferase MtaA/CmuA family; KEGG: msi:Msm_0518 methylcobalamin:coenzyme M methyltransferase, MtaA; TIGRFAM: Methyltransferase MtaA/CmuA; PFAM: Uroporphyrinogen decarboxylase (URO-D).


ensembl_gene_id: Metbo_1026
symbol: ADZ09273.1
gene_biotype: protein_coding
description:
  PFAM: 4-oxalocrotonate tautomerase; KEGG: aar:Acear_1896 4-oxalocrotonate tautomerase family enzyme.


ensembl_gene_id: Metbo_1029
symbol: ADZ09276.1
gene_biotype: protein_coding
description:
  KEGG: mmg:MTBMA_c06620 ferrous iron transport protein B; TIGRFAM: Ferrous iron transport protein B; Small GTP-binding protein; PFAM: Ferrous iron transport protein B, N-terminal; GTP-binding protein, HSR1-related; Nucleoside recognition; Ferrous iron transport protein B, C-terminal.


ensembl_gene_id: Metbo_1030
symbol: ADZ09277.1
gene_biotype: protein_coding
description:
  Iron (metal) dependent repressor, DtxR family; KEGG: mmg:MTBMA_c06630 iron-dependent transcriptional regulator containing a FeoA domain; PFAM: Iron dependent repressor; Iron dependent repressor, N-terminal; Ferrous iron transporter, FeoA subunit; SMART: Iron dependent repressor, diptheria toxin type; Ferrous iron transporter, FeoA subunit.


ensembl_gene_id: Metbo_1031
symbol: ADZ09278.1
gene_biotype: protein_coding
description:
  SMART: ATPase, P-type cation-transporter, N-terminal; TIGRFAM: ATPase, P-type, plasma-membrane proton-efflux; ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter; KEGG: mbu:Mbur_0068 plasma-membrane proton-efflux P-type ATPase; PFAM: ATPase, P-type, ATPase-associated domain; ATPase, P-type cation-transporter, N-terminal; Haloacid dehalogenase-like hydrolase.


ensembl_gene_id: Metbo_1035
symbol: ADZ09282.1
gene_biotype: protein_coding
description:
  TrkA-N domain protein; PFAM: Regulator of K+ conductance, N-terminal; Regulator of K+ conductance, C-terminal; KEGG: mmg:MTBMA_c16520 potassium uptake protein TrkA.


ensembl_gene_id: Metbo_1039
symbol: ADZ09286.1
gene_biotype: protein_coding
description:
  KEGG: rci:RCIX980 putative signal transduction histidine kinase; PFAM: Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain; ATPase-like, ATP-binding domain; SMART: ATPase-like, ATP-binding domain.


ensembl_gene_id: Metbo_1040
symbol: ADZ09287.1
gene_biotype: protein_coding
description:
  Cation diffusion facilitator family transporter; KEGG: mmg:MTBMA_c04620 transporter protein; TIGRFAM: Cation efflux protein; PFAM: Cation efflux protein.


ensembl_gene_id: Metbo_1041
symbol: ADZ09288.1
gene_biotype: protein_coding
description:
  PFAM: Heat shock protein Hsp20; KEGG: mfv:Mfer_1265 heat shock protein HSP20; Belongs to the small heat shock protein (HSP20) family.


ensembl_gene_id: Metbo_1044
symbol: ADZ09291.1
gene_biotype: protein_coding
description:
  Response regulator receiver protein; KEGG: nhl:Nhal_1443 PAS sensor protein; PFAM: Signal transduction response regulator, receiver domain; SMART: Signal transduction response regulator, receiver domain.


ensembl_gene_id: Metbo_1045
symbol: ADZ09292.1
gene_biotype: protein_coding
description:
  PFAM: Activator of Hsp90 ATPase homologue 1-like; KEGG: phe:Phep_2331 activator of HSP90 ATPase 1 family protein.


ensembl_gene_id: Metbo_1047
symbol: ADZ09294.1
gene_biotype: protein_coding
description:
  Capsule synthesis protein, CapA; KEGG: mru:mru_1047 poly-gamma-glutamate biosynthesis protein; PFAM: Capsule synthesis protein, CapA; SMART: Capsule synthesis protein, CapA.


ensembl_gene_id: Metbo_1049
symbol: ADZ09296.1
gene_biotype: protein_coding
description:
  TIGRFAM: PAS; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS fold; KEGG: mpl:Mpal_0667 PAS/PAC sensor signal transduction histidine kinase; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain.


ensembl_gene_id: Metbo_1053
symbol: ADZ09300.1
gene_biotype: protein_coding
description:
  TIGRFAM: Bacterial carbamate kinase; KEGG: mem:Memar_0247 carbamate kinase; PFAM: Aspartate/glutamate/uridylate kinase; Belongs to the carbamate kinase family.


ensembl_gene_id: Metbo_1054
symbol: ADZ09301.1
gene_biotype: protein_coding
description:
  KEGG: mfv:Mfer_1029 radical sam domain protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB.


ensembl_gene_id: Metbo_1059
symbol: ADZ09306.1
gene_biotype: protein_coding
description:
  Phosphonate-transporting ATPase; PFAM: ABC transporter-like; KEGG: mpd:MCP_1847 ABC transporter ATP binding protein; SMART: ATPase, AAA+ type, core.


ensembl_gene_id: Metbo_1065
symbol: ADZ09311.1
gene_biotype: protein_coding
description:
  Metallophosphoesterase; PFAM: Metallo-dependent phosphatase; KEGG: ppn:Palpr_2305 metallophosphoesterase.


ensembl_gene_id: Metbo_1073
symbol: ADZ09318.1
gene_biotype: protein_coding
description:
  KEGG: dae:Dtox_1619 drug resistance transporter, EmrB/QacA subfamily; TIGRFAM: Drug resistance transporter EmrB/QacA subfamily; PFAM: Major facilitator superfamily MFS-1.


ensembl_gene_id: Metbo_1078
symbol: ADZ09323.1
gene_biotype: protein_coding
description:
  Conserved repeat domain protein; TIGRFAM: Domain of unknown function DUF11; KEGG: mst:Msp_0590 asn/thr-rich large protein family protein.


ensembl_gene_id: Metbo_1079
symbol: ADZ09324.1
gene_biotype: protein_coding
description:
  PFAM: Signal transduction response regulator, receiver domain; KEGG: npu:Npun_F6364 multi-sensor hybrid histidine kinase.


ensembl_gene_id: Metbo_1081
symbol: pheS
gene_biotype: protein_coding
description:
  TIGRFAM: Phenylalanyl-tRNA synthetase, class IIc, alpha subunit; HAMAP: Phenylalanyl-tRNA synthetase alpha chain 2, bacterial/archaeal; KEGG: mmg:MTBMA_c11370 phenylalanyl-tRNA synthetase, alpha subunit; PFAM: Phenylalanyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.


ensembl_gene_id: Metbo_1082
symbol: ADZ09327.1
gene_biotype: protein_coding
description:
  PFAM: Triphosphoribosyl-dephospho-CoA protein; KEGG: mfv:Mfer_1255 triphosphoribosyl-dephospho-CoA protein.


ensembl_gene_id: Metbo_1083
symbol: ADZ09328.1
gene_biotype: protein_coding
description:
  Porphobilinogen synthase; KEGG: mru:mru_1560 delta-aminolevulinic acid dehydratase HemB; PFAM: Tetrapyrrole biosynthesis, porphobilinogen synthase; Belongs to the ALAD family.


ensembl_gene_id: Metbo_1085
symbol: ADZ09330.1
gene_biotype: protein_coding
description:
  HhH-GPD family protein; KEGG: mba:Mbar_A3333 DNA-3-methyladenine glycosylase III; PFAM: HhH-GPD domain; SMART: HhH-GPD domain.


ensembl_gene_id: Metbo_1088
symbol: aroC
gene_biotype: protein_coding
description:
  Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.


ensembl_gene_id: Metbo_1090
symbol: ADZ09335.1
gene_biotype: protein_coding
description:
  Protein of unknown function UPF0118; PFAM: Uncharacterised protein family UPF0118; KEGG: mma:MM_2752 hypothetical protein.


ensembl_gene_id: Metbo_1091
symbol: ADZ09336.1
gene_biotype: protein_coding
description:
  PFAM: Rubredoxin-type Fe(Cys)4 protein; KEGG: mth:MTH1352 rubredoxin; Belongs to the rubredoxin family.


ensembl_gene_id: Metbo_1092
symbol: ADZ09337.1
gene_biotype: protein_coding
description:
  Polyamine-transporting ATPase; PFAM: ABC transporter-like; Transport-associated OB, type 1; KEGG: mfv:Mfer_0982 tungstate/molybdate transport system ATP-binding protein; SMART: ATPase, AAA+ type, core.


ensembl_gene_id: Metbo_1093
symbol: ADZ09338.1
gene_biotype: protein_coding
description:
  ABC-type transporter, integral membrane subunit; PFAM: Binding-protein-dependent transport systems inner membrane component; KEGG: mfv:Mfer_0983 tungstate/molybdate transport system permease protein.


ensembl_gene_id: Metbo_1094
symbol: ADZ09339.1
gene_biotype: protein_coding
description:
  KEGG: mru:mru_1269 molybdenum-pterin binding protein Mop1; TIGRFAM: Molybdenum-pterin binding; PFAM: Transport-associated OB, type 1.


ensembl_gene_id: Metbo_1095
symbol: ADZ09340.1
gene_biotype: protein_coding
description:
  TIGRFAM: ATPase, P type, cation/copper-transporter; ATPase, P-type, heavy metal translocating; ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter; KEGG: mev:Metev_1829 copper-translocating P-type ATPase; PFAM: ATPase, P-type, ATPase-associated domain; Haloacid dehalogenase-like hydrolase.


ensembl_gene_id: Metbo_1099
symbol: ADZ09344.1
gene_biotype: protein_coding
description:
  KEGG: mmg:MTBMA_c08430 sensory transduction regulatory protein; PFAM: Signal transduction response regulator, receiver domain; SMART: Signal transduction response regulator, receiver domain.


ensembl_gene_id: Metbo_1100
symbol: ADZ09345.1
gene_biotype: protein_coding
description:
  TIGRFAM: PAS; PFAM: Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain; Signal transduction response regulator, receiver domain; PAS fold; ATPase-like, ATP-binding domain; KEGG: mth:MTH902 sensory transduction histidine kinase; SMART: Signal transduction response regulator, receiver domain; ATPase-like, ATP-binding domain.


ensembl_gene_id: Metbo_1101
symbol: ADZ09346.1
gene_biotype: protein_coding
description:
  KEGG: mmg:MTBMA_c08410 sensory transduction regulatory protein; PFAM: Signal transduction response regulator, receiver domain; SMART: Signal transduction response regulator, receiver domain.


ensembl_gene_id: Metbo_1102
symbol: ADZ09347.1
gene_biotype: protein_coding
description:
  Histidine kinase; KEGG: mth:MTH444 sensory transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain.


ensembl_gene_id: Metbo_1103
symbol: uvrA
gene_biotype: protein_coding
description:
  UvrABC system protein A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.


ensembl_gene_id: Metbo_1104
symbol: uvrB
gene_biotype: protein_coding
description:
  UvrABC system protein B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and [...]


ensembl_gene_id: Metbo_1110
symbol: ADZ09355.1
gene_biotype: protein_coding
description:
  KEGG: cte:CT1466 TIR domain-containing protein; PFAM: Toll-Interleukin receptor; SMART: Toll-Interleukin receptor.


ensembl_gene_id: Metbo_1114
symbol: ADZ09359.1
gene_biotype: protein_coding
description:
  PFAM: Restriction endonuclease, type I, S subunit, EcoBI; KEGG: mmw:Mmwyl1_3199 restriction modification system DNA specificity subunit.


ensembl_gene_id: Metbo_1116
symbol: ADZ09361.1
gene_biotype: protein_coding
description:
  Type I site-specific deoxyribonuclease; SMART: DEAD-like helicase, N-terminal; manually curated; KEGG: mmq:MmarC5_1171 type III restriction enzyme, res subunit; PFAM: Restriction endonuclease, type I, R subunit/Type III, Res subunit; Restriction endonuclease, type I, EcoRI, R subunit/Type III, Res subunit, N-terminal; Helicase, C-terminal.


ensembl_gene_id: Metbo_1117
symbol: ADZ09362.1
gene_biotype: protein_coding
description:
  Putative transcriptional regulator; PFAM: ATPase, AAA-4; KEGG: mac:MA2370 ATP-dependent DNA helicase.


ensembl_gene_id: Metbo_1118
symbol: ADZ09363.1
gene_biotype: protein_coding
description:
  RelA/SpoT domain protein; KEGG: pfs:PFLU1597 hypothetical protein; PFAM: RelA/SpoT; SMART: RelA/SpoT.


ensembl_gene_id: Metbo_1142
symbol: ADZ09386.1
gene_biotype: protein_coding
description:
  Integrase family protein; PFAM: Integrase, catalytic core, phage; KEGG: msi:Msm_1640 DNA intergrase/recombinase.


ensembl_gene_id: Metbo_1143
symbol: uvrC
gene_biotype: protein_coding
description:
  UvrABC system protein C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.


ensembl_gene_id: Metbo_1144
symbol: ADZ09388.1
gene_biotype: protein_coding
description:
  Putative PAS/PAC sensor protein; TIGRFAM: PAS; PFAM: Signal transduction response regulator, receiver domain; PAS fold-4; KEGG: mth:MTH440 sensory transduction regulatory protein; SMART: Signal transduction response regulator, receiver domain; PAS; PAC motif.


ensembl_gene_id: Metbo_1145
symbol: ADZ09389.1
gene_biotype: protein_coding
description:
  PFAM: Circadian clock protein KaiC/DNA repair protein RadA; KEGG: mmg:MTBMA_c00830 hypothetical protein.


ensembl_gene_id: Metbo_1150
symbol: ADZ09394.1
gene_biotype: protein_coding
description:
  Hypothetical protein; PFAM: Class III signal peptide motif; KEGG: mmg:MTBMA_c08200 hypothetical protein.


ensembl_gene_id: Metbo_1155
symbol: ADZ09399.1
gene_biotype: protein_coding
description:
  Hypothetical protein; PFAM: Class III signal peptide motif; KEGG: mmg:MTBMA_c08240 hypothetical protein.


ensembl_gene_id: Metbo_1158
symbol: ADZ09402.1
gene_biotype: protein_coding
description:
  Universal metal-binding-domain/4Fe-4S-binding-domain containing ABC transporter protein; KEGG: mmg:MTBMA_c08270 ATPase; TIGRFAM: Conserved hypothetical protein CHP03679, ATP-binding; Conserved hypothetical protein CHP00289; Domain of unknown function DUF71, ATP-binding domain; PFAM: Domain of unknown function DUF71, ATP-binding domain.


ensembl_gene_id: Metbo_1161
symbol: ADZ09405.1
gene_biotype: protein_coding
description:
  PFAM: Transcription regulator, TetR-like, DNA-binding, bacterial/archaeal; KEGG: mac:MA2902 TetR family transcriptional regulator.


ensembl_gene_id: Metbo_1162
symbol: ADZ09406.1
gene_biotype: protein_coding
description:
  Protein of unknown function DUF54; PFAM: Uncharacterised protein family UPF0201; KEGG: mfv:Mfer_0658 hypothetical protein; Belongs to the UPF0201 family.


ensembl_gene_id: Metbo_1163
symbol: ADZ09407.1
gene_biotype: protein_coding
description:
  UPF0200 protein; HAMAP: Nucleoside triphosphate hydrolase-related; KEGG: mst:Msp_0561 dephospho-CoA kinase; Belongs to the UPF0200 family.


ensembl_gene_id: Metbo_1168
symbol: ADZ09412.1
gene_biotype: protein_coding
description:
  PFAM: Peptidase A24A-predicted, C-terminal archaea; Peptidase A24A, prepilin type IV; KEGG: mth:MTH421 hypothetical protein.


ensembl_gene_id: Metbo_1169
symbol: pyrG
gene_biotype: protein_coding
description:
  CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.


ensembl_gene_id: Metbo_1170
symbol: ADZ09414.1
gene_biotype: protein_coding
description:
  PFAM: CobB/CobQ-like glutamine amidotransferase; KEGG: mfv:Mfer_1210 CobB/CobQ domain protein glutamine amidotransferase.


ensembl_gene_id: Metbo_1171
symbol: ADZ09415.1
gene_biotype: protein_coding
description:
  Domain of unknown function DUF1727; KEGG: mfv:Mfer_1209 hypothetical protein; manually curated; PFAM: Domain of unknown function DUF1727; Mur ligase, central.


ensembl_gene_id: Metbo_1172
symbol: apgM
gene_biotype: protein_coding
description:
  Proposed homoserine kinase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.


ensembl_gene_id: Metbo_1173
symbol: ADZ09417.1
gene_biotype: protein_coding
description:
  KEGG: mst:Msp_0487 homoserine dehydrogenase; PFAM: Homoserine dehydrogenase, catalytic; Aspartate/homoserine dehydrogenase, NAD-binding.


ensembl_gene_id: Metbo_1175
symbol: ADZ09419.1
gene_biotype: protein_coding
description:
  TIGRFAM: Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase, subunit C, putative; KEGG: mst:Msp_0489 aspartyl/glutamyl-tRNA amidotransferase subunit C.


ensembl_gene_id: Metbo_1176
symbol: ADZ09420.1
gene_biotype: protein_coding
description:
  KEGG: mst:Msp_0490 putative asparagine synthetase; TIGRFAM: Asparagine synthase, glutamine-hydrolyzing; PFAM: Asparagine synthase; Glutamine amidotransferase, class-II.


ensembl_gene_id: Metbo_1179
symbol: ADZ09423.1
gene_biotype: protein_coding
description:
  TIGRFAM: Cysteine synthase A; Cysteine synthase K/M; KEGG: mru:mru_1574 cysteine synthase CysKM1; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit.


ensembl_gene_id: Metbo_1180
symbol: ADZ09424.1
gene_biotype: protein_coding
description:
  Nitrogenase; KEGG: mbn:Mboo_2008 nitrogenase iron protein; PFAM: Nitrogenase iron protein, subunit NifH/Protochlorophyllide reductase, subunit ChlL; Belongs to the NifH/BchL/ChlL family.


ensembl_gene_id: Metbo_1183
symbol: ADZ09427.1
gene_biotype: protein_coding
description:
  PFAM: Dinitrogenase iron-molybdenum cofactor biosynthesis; KEGG: cbe:Cbei_0627 dinitrogenase iron-molybdenum cofactor biosynthesis protein.


ensembl_gene_id: Metbo_1184
symbol: ADZ09428.1
gene_biotype: protein_coding
description:
  Cystathionine beta-lyase; KEGG: dly:Dehly_0142 class I and II aminotransferase; PFAM: Aminotransferase, class I/classII.


ensembl_gene_id: Metbo_1188
symbol: ADZ09432.1
gene_biotype: protein_coding
description:
  KEGG: mfv:Mfer_1084 transglutaminase domain protein; PFAM: Transglutaminase-like; SMART: Transglutaminase-like.


ensembl_gene_id: Metbo_1192
symbol: ADZ09436.1
gene_biotype: protein_coding
description:
  KEGG: mth:MTH359 hypothetical protein; PFAM: Transglutaminase-like; Pseudomurein-binding repeat; SMART: Transglutaminase-like.


ensembl_gene_id: Metbo_1196
symbol: ADZ09440.1
gene_biotype: protein_coding
description:
  KEGG: mfs:MFS40622_0470 transcriptional regulator, XRE family; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3.


ensembl_gene_id: Metbo_1202
symbol: ADZ09445.1
gene_biotype: protein_coding
description:
  KEGG: mmg:MTBMA_c05680 ATP phosphoribosyltransferase; TIGRFAM: ATP phosphoribosyltransferase, catalytic domain; PFAM: ATP phosphoribosyltransferase, catalytic domain.


ensembl_gene_id: Metbo_1205
symbol: ADZ09448.1
gene_biotype: protein_coding
description:
  Methyl-viologen-reducing hydrogenase delta subunit; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).


ensembl_gene_id: Metbo_1208
symbol: ADZ09451.1
gene_biotype: protein_coding
description:
  PFAM: UBA/THIF-type NAD/FAD binding fold; MoeZ/MoeB; KEGG: mbn:Mboo_1985 UBA/ThiF-type NAD/FAD binding protein.


ensembl_gene_id: Metbo_1209
symbol: ADZ09452.1
gene_biotype: protein_coding
description:
  PFAM: Glucose-methanol-choline oxidoreductase, N-terminal; Lycopene cyclase-type, FAD-binding; 4Fe-4S binding domain; KEGG: mfv:Mfer_0927 glucose-methanol-choline oxidoreductase.


ensembl_gene_id: Metbo_1210
symbol: cysS
gene_biotype: protein_coding
description:
  SMART: Cysteinyl-tRNA synthetase, class Ia, DALR; TIGRFAM: Cysteinyl-tRNA synthetase, class Ia; KEGG: mst:Msp_0124 hypothetical protein; PFAM: Cysteinyl-tRNA synthetase, class Ia; Cysteinyl-tRNA synthetase, class Ia, DALR; Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: Metbo_1211
symbol: ADZ09454.1
gene_biotype: protein_coding
description:
  PFAM: Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain; KEGG: mth:MTH413 hypothetical protein.


ensembl_gene_id: Metbo_1212
symbol: ADZ09455.1
gene_biotype: protein_coding
description:
  TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; KEGG: mbu:Mbur_0797 O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism, pyridoxal phosphate-dependent enzyme.


ensembl_gene_id: Metbo_1213
symbol: metXA
gene_biotype: protein_coding
description:
  Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.


ensembl_gene_id: Metbo_1214
symbol: iscS
gene_biotype: protein_coding
description:
  Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.


ensembl_gene_id: Metbo_1223
symbol: ADZ09465.1
gene_biotype: protein_coding
description:
  Manually curated; PFAM: Signal transduction response regulator, receiver domain; KEGG: lbl:LBL_2788 histidine kinase of a two-component regulator system; SMART: Signal transduction response regulator, receiver domain.


ensembl_gene_id: Metbo_1226
symbol: ADZ09468.1
gene_biotype: protein_coding
description:
  PAS sensor protein; KEGG: cyj:Cyan7822_3932 PAS/PAC and GAF sensors-containing diguanylate cyclase; TIGRFAM: PAS; SMART: PAC motif; PAS.


ensembl_gene_id: Metbo_1227
symbol: ADZ09469.1
gene_biotype: protein_coding
description:
  PFAM: Transcription regulator PadR N-terminal-like; KEGG: mpl:Mpal_2037 transcriptional regulator, PadR-like family.


ensembl_gene_id: Metbo_1229
symbol: ADZ09471.1
gene_biotype: protein_coding
description:
  KEGG: mth:MTH859 heat shock protein, class I; Belongs to the small heat shock protein (HSP20) family.


ensembl_gene_id: Metbo_1231
symbol: ADZ09473.1
gene_biotype: protein_coding
description:
  KEGG: msi:Msm_0263 nitrogen fixation protein, NifU; TIGRFAM: NIF system FeS cluster assembly, NifU-like; PFAM: NIF system FeS cluster assembly, NifU, N-terminal.


ensembl_gene_id: Metbo_1234
symbol: ADZ09476.1
gene_biotype: protein_coding
description:
  KEGG: mem:Memar_2130 PfpI family intracellular peptidase; TIGRFAM: Peptidase C56, PfpI; PFAM: ThiJ/PfpI.


ensembl_gene_id: Metbo_1235
symbol: ADZ09477.1
gene_biotype: protein_coding
description:
  TIGRFAM: PAS; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS fold-4; PAS fold; KEGG: mpl:Mpal_0908 multi-sensor signal transduction histidine kinase; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS.


ensembl_gene_id: Metbo_1236
symbol: ADZ09478.1
gene_biotype: protein_coding
description:
  KEGG: mac:MA1268 response regulator receiver; PFAM: Signal transduction response regulator, receiver domain; SMART: Signal transduction response regulator, receiver domain.


ensembl_gene_id: Metbo_1237
symbol: ADZ09479.1
gene_biotype: protein_coding
description:
  Putative PAS/PAC sensor protein; TIGRFAM: PAS; PFAM: PAS fold; Signal transduction response regulator, receiver domain; KEGG: bph:Bphy_1145 multi-sensor signal transduction histidine kinase; SMART: Signal transduction response regulator, receiver domain; PAS; PAC motif.


ensembl_gene_id: Metbo_1238
symbol: ADZ09480.1
gene_biotype: protein_coding
description:
  KEGG: thx:Thet_1750 ArsR family transcriptional regulator; PFAM: HTH transcriptional regulator, ArsR; SMART: HTH transcriptional regulator, ArsR.


ensembl_gene_id: Metbo_1239
symbol: ADZ09481.1
gene_biotype: protein_coding
description:
  TIGRFAM: ATPase, P-type, heavy metal translocating; ATPase, P-type, heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating; ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter; KEGG: mst:Msp_0121 cation transport ATPase; PFAM: ATPase, P-type, ATPase-associated domain; Haloacid dehalogenase-like hydrolase.


ensembl_gene_id: Metbo_1245
symbol: ADZ09487.1
gene_biotype: protein_coding
description:
  KEGG: mfv:Mfer_0791 cation diffusion facilitator family transporter; TIGRFAM: Cation efflux protein; PFAM: Cation efflux protein; Dinitrogenase iron-molybdenum cofactor biosynthesis.


ensembl_gene_id: Metbo_1248
symbol: ADZ09490.1
gene_biotype: protein_coding
description:
  Alkylhydroperoxidase like protein, AhpD family; KEGG: mtp:Mthe_0782 alkylhydroperoxidase; TIGRFAM: Alkylhydroperoxidase AhpD core; PFAM: Carboxymuconolactone decarboxylase.


ensembl_gene_id: Metbo_1251
symbol: ADZ09493.1
gene_biotype: protein_coding
description:
  PFAM: Major facilitator superfamily MFS-1; KEGG: msi:Msm_1210 efflux pump antibiotic resistance protein.


ensembl_gene_id: Metbo_1253
symbol: ADZ09495.1
gene_biotype: protein_coding
description:
  PFAM: ABC transporter-like; KEGG: mka:MK1654 ATPase subunit of a ABC-type transport system involved in lipoprotein release; SMART: ATPase, AAA+ type, core.


ensembl_gene_id: Metbo_1254
symbol: ADZ09496.1
gene_biotype: protein_coding
description:
  PFAM: Domain of unknown function DUF214, ABC transporter permease; KEGG: mru:mru_1702 ABC transporter permease protein.


ensembl_gene_id: Metbo_1255
symbol: ADZ09497.1
gene_biotype: protein_coding
description:
  Regulatory protein ArsR; PFAM: HTH transcriptional regulator, ArsR; KEGG: mmg:MTBMA_c00250 transcriptional regulator.


ensembl_gene_id: Metbo_1257
symbol: ADZ09499.1
gene_biotype: protein_coding
description:
  Transcriptional regulator, PadR-like family; PFAM: Transcription regulator PadR N-terminal-like; KEGG: cac:CA_C0571 transcriptional regulator.


ensembl_gene_id: Metbo_1258
symbol: ADZ09500.1
gene_biotype: protein_coding
description:
  Glutathione synthase; KEGG: cac:CA_C1540 hypothetical protein; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain.


ensembl_gene_id: Metbo_1263
symbol: pdxS
gene_biotype: protein_coding
description:
  Pyridoxal biosynthesis lyase pdxS; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family.


ensembl_gene_id: Metbo_1264
symbol: ADZ09506.1
gene_biotype: protein_coding
description:
  MOSC domain containing protein; PFAM: Molybdenum cofactor sulfurase, C-terminal; KEGG: dhd:Dhaf_1402 MOSC domain containing protein.


ensembl_gene_id: Metbo_1266
symbol: thiI
gene_biotype: protein_coding
description:
  tRNA sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.


ensembl_gene_id: Metbo_1268
symbol: ADZ09510.1
gene_biotype: protein_coding
description:
  KEGG: bba:Bd3795 cystathionine gamma-lyase; PFAM: Cys/Met metabolism, pyridoxal phosphate-dependent enzyme.


ensembl_gene_id: Metbo_1269
symbol: ADZ09511.1
gene_biotype: protein_coding
description:
  CBS domain containing protein; PFAM: Cystathionine beta-synthase, core; KEGG: mmg:MTBMA_c08050 CBS-domain-containing protein.


ensembl_gene_id: Metbo_1271
symbol: ADZ09513.1
gene_biotype: protein_coding
description:
  PfkB domain protein; PFAM: Carbohydrate/purine kinase; KEGG: mmg:MTBMA_c08030 energy-converting hydrogenase T, subunit T; Belongs to the carbohydrate kinase PfkB family.


ensembl_gene_id: Metbo_1272
symbol: ADZ09514.1
gene_biotype: protein_coding
description:
  Formylmethanofuran--tetrahydromethanopterin N-formyltransferase; KEGG: mfv:Mfer_1096 formylmethanofuran-tetrahydromethanopterin formyltransferase; PFAM: Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr, C-terminal; Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr, N-terminal.


ensembl_gene_id: Metbo_1274
symbol: ADZ09516.1
gene_biotype: protein_coding
description:
  4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; KEGG: mmg:MTBMA_c08000 energy-converting hydrogenase A, subunit Q; manually curated; PFAM: 4Fe-4S binding domain.


ensembl_gene_id: Metbo_1275
symbol: ADZ09517.1
gene_biotype: protein_coding
description:
  4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; PFAM: 4Fe-4S binding domain; KEGG: mmg:MTBMA_c07990 energy-converting hydrogenase A, subunit P.


ensembl_gene_id: Metbo_1276
symbol: ADZ09518.1
gene_biotype: protein_coding
description:
  NADH dehydrogenase (quinone); KEGG: mmg:MTBMA_c07980 energy-converting hydrogenase A, subunit O; PFAM: NADH-quinone oxidoreductase, subunit D; Nickel-dependent hydrogenase, large subunit.


ensembl_gene_id: Metbo_1277
symbol: ADZ09519.1
gene_biotype: protein_coding
description:
  PFAM: NADH:ubiquinone oxidoreductase-like, 20kDa subunit; KEGG: mmg:MTBMA_c07970 energy-converting hydrogenase A, subunit N.


ensembl_gene_id: Metbo_1279
symbol: ADZ09521.1
gene_biotype: protein_coding
description:
  PFAM: Protein of unknown function DUF2104, membrane; KEGG: mru:mru_1401 energy-converting hydrogenase A subunit L EhaL.


ensembl_gene_id: Metbo_1281
symbol: ADZ09523.1
gene_biotype: protein_coding
description:
  PFAM: NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H; KEGG: mth:MTH393 NADH dehydrogenase (ubiquinone), subunit 1 related protein.


ensembl_gene_id: Metbo_1283
symbol: ADZ09525.1
gene_biotype: protein_coding
description:
  PFAM: [NiFe]-hydrogenase-3-type complex Eha, membrane protein EhaH, predicted; KEGG: mth:MTH391 NADH dehydrogenase I, subunit N related protein.


ensembl_gene_id: Metbo_1284
symbol: ADZ09526.1
gene_biotype: protein_coding
description:
  PFAM: Protein of unknown function DUF2105, membrane; KEGG: mru:mru_1406 energy-converting hydrogenase A subunit G EhaG.


ensembl_gene_id: Metbo_1285
symbol: ADZ09527.1
gene_biotype: protein_coding
description:
  PFAM: [NiFe]-hydrogenase-3-type complex Eha, membrane protein EhaF; KEGG: mmg:MTBMA_c07890 energy-converting hydrogenase A, subunit F.


ensembl_gene_id: Metbo_1286
symbol: ADZ09528.1
gene_biotype: protein_coding
description:
  PFAM: [NiFe]-hydrogenase-3-type complex Eha, membrane protein EhaE; KEGG: mth:MTH388 hypothetical protein.


ensembl_gene_id: Metbo_1288
symbol: ADZ09530.1
gene_biotype: protein_coding
description:
  PFAM: Protein of unknown function DUF2109, membrane; KEGG: mmg:MTBMA_c07860 energy-converting hydrogenase A, subunit C.


ensembl_gene_id: Metbo_1299
symbol: ADZ09541.1
gene_biotype: protein_coding
description:
  KEGG: cpy:Cphy_3485 peptidase T-like protein; TIGRFAM: Peptidase M20B, peptidase T; PFAM: Peptidase M20, dimerisation; Peptidase M20.


ensembl_gene_id: Metbo_1301
symbol: ADZ09543.1
gene_biotype: protein_coding
description:
  KEGG: htu:Htur_3661 sugar transporter; TIGRFAM: Sugar/inositol transporter; PFAM: General substrate transporter.


ensembl_gene_id: Metbo_1310
symbol: ADZ09552.1
gene_biotype: protein_coding
description:
  KEGG: mpd:MCP_1700 putative PadR-like family transcriptional regulator; manually curated; PFAM: Transcription regulator PadR N-terminal-like.


ensembl_gene_id: Metbo_1318
symbol: ADZ09560.1
gene_biotype: protein_coding
description:
  PFAM: Glycosyl transferase, family 2; KEGG: mac:MA1187 dolichyl-phosphate beta-D-mannosyltransferase.


ensembl_gene_id: Metbo_1319
symbol: ADZ09561.1
gene_biotype: protein_coding
description:
  Protein of unknown function DUF131; KEGG: mfv:Mfer_0836 hypothetical protein; TIGRFAM: Protein of unknown function DUF131; PFAM: Protein of unknown function DUF131.


ensembl_gene_id: Metbo_1327
symbol: ADZ09568.1
gene_biotype: protein_coding
description:
  MCP methyltransferase/methylesterase, CheR/CheB; PFAM: MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal; Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase; MCP methyltransferase, CheR-type, all-alpha domain, N-terminal; KEGG: mbn:Mboo_0327 putative PAS/PAC sensor protein; SMART: MCP methyltransferase, CheR-type.


ensembl_gene_id: Metbo_1328
symbol: ADZ09569.1
gene_biotype: protein_coding
description:
  TIGRFAM: PAS; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS fold; KEGG: mac:MA1270 sensory transduction histidine kinase; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS.


ensembl_gene_id: Metbo_1329
symbol: ADZ09570.1
gene_biotype: protein_coding
description:
  TIGRFAM: PAS; PFAM: Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain; ATPase-like, ATP-binding domain; KEGG: mmg:MTBMA_c08550 sensory transduction histidine kinase; SMART: ATPase-like, ATP-binding domain.


ensembl_gene_id: Metbo_1331
symbol: ADZ09572.1
gene_biotype: protein_coding
description:
  Pseudomurein-binding repeat-containing protein; PFAM: Pseudomurein-binding repeat; KEGG: cpo:COPRO5265_0448 endoxylanase.


ensembl_gene_id: Metbo_1335
symbol: ADZ09576.1
gene_biotype: protein_coding
description:
  Roadblock/LC7 family protein; KEGG: mth:MTH595 hypothetical protein; PFAM: Dynein light chain-related; SMART: Dynein light chain-related.


ensembl_gene_id: Metbo_1336
symbol: ADZ09577.1
gene_biotype: protein_coding
description:
  TIGRFAM: Small GTP-binding protein; PFAM: Mitochondrial Rho-like; KEGG: mth:MTH594 hypothetical protein; SMART: Ras small GTPase, Rab type.


ensembl_gene_id: Metbo_1339
symbol: ADZ09580.1
gene_biotype: protein_coding
description:
  KEGG: mmg:MTBMA_c09710 hypothetical protein; PFAM: Tetratricopeptide TPR-1; SMART: Tetratricopeptide repeat.


ensembl_gene_id: Metbo_1342
symbol: ADZ09582.1
gene_biotype: protein_coding
description:
  PFAM: Resolvase, helix-turn-helix domain; AT hook, DNA-binding motif; KEGG: mmg:MTBMA_c09690 hypothetical protein.


ensembl_gene_id: Metbo_1344
symbol: metG
gene_biotype: protein_coding
description:
  Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.


ensembl_gene_id: Metbo_1346
symbol: priL
gene_biotype: protein_coding
description:
  DNA primase, large subunit; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.


ensembl_gene_id: Metbo_1347
symbol: priS
gene_biotype: protein_coding
description:
  DNA primase small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis.  [...]


ensembl_gene_id: Metbo_1350
symbol: ADZ09590.1
gene_biotype: protein_coding
description:
  Conserved repeat domain protein; KEGG: cpi:Cpin_5368 outer membrane adhesin like protein; TIGRFAM: Domain of unknown function DUF11; VCBS repeat; PFAM: Hyalin.


ensembl_gene_id: Metbo_1351
symbol: ADZ09591.1
gene_biotype: protein_coding
description:
  Putative PAS/PAC sensor protein; KEGG: pca:Pcar_2709 two component signal transduction response regulator; PFAM: Signal transduction response regulator, receiver domain; PAS fold-3; SMART: Signal transduction response regulator, receiver domain.


ensembl_gene_id: Metbo_1352
symbol: ADZ09592.1
gene_biotype: protein_coding
description:
  Putative PAS/PAC sensor protein; TIGRFAM: PAS; PFAM: Signal transduction response regulator, receiver domain; PAS fold; KEGG: mth:MTH457 sensory transduction regulatory protein; SMART: Signal transduction response regulator, receiver domain; PAS.


ensembl_gene_id: Metbo_1353
symbol: ADZ09593.1
gene_biotype: protein_coding
description:
  TIGRFAM: PAS; PFAM: Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain; PAS fold-4; ATPase-like, ATP-binding domain; KEGG: mev:Metev_1165 signal transduction histidine kinase; SMART: ATPase-like, ATP-binding domain.


ensembl_gene_id: Metbo_1354
symbol: ADZ09594.1
gene_biotype: protein_coding
description:
  Response regulator receiver; KEGG: mba:Mbar_A3448 putative transcriptional regulator; PFAM: Signal transduction response regulator, receiver domain; SMART: Signal transduction response regulator, receiver domain.


ensembl_gene_id: Metbo_1356
symbol: ADZ09596.1
gene_biotype: protein_coding
description:
  KEGG: mru:mru_2118 signal peptidase I; TIGRFAM: Peptidase S26B, eukaryotic signal peptidase; PFAM: Peptidase S24/S26A/S26B, conserved region.


ensembl_gene_id: Metbo_1357
symbol: cca
gene_biotype: protein_coding
description:
  CCA-adding enzyme; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.


ensembl_gene_id: Metbo_1358
symbol: ADZ09598.1
gene_biotype: protein_coding
description:
  2'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family.


ensembl_gene_id: Metbo_1360
symbol: aroB
gene_biotype: protein_coding
description:
  3-dehydroquinate synthase; Catalyzes the oxidative deamination and cyclization of 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis; Belongs to the archaeal-type DHQ synthase family.


ensembl_gene_id: Metbo_1361
symbol: aroA-2
gene_biotype: protein_coding
description:
  Phospho-2-dehydro-3-deoxyheptonate aldolase; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids.


ensembl_gene_id: Metbo_1365
symbol: ADZ09605.1
gene_biotype: protein_coding
description:
  HI0933 family protein; KEGG: cth:Cthe_0708 FAD dependent oxidoreductase; TIGRFAM: Conserved hypothetical protein CHP00275, flavoprotein HI0933-like; PFAM: Conserved hypothetical protein CHP00275, flavoprotein HI0933-like.


ensembl_gene_id: Metbo_1366
symbol: aspS
gene_biotype: protein_coding
description:
  aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).


ensembl_gene_id: Metbo_1367
symbol: hisD
gene_biotype: protein_coding
description:
  Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.


ensembl_gene_id: Metbo_1368
symbol: ADZ09608.1
gene_biotype: protein_coding
description:
  Protein of unknown function UPF0058; PFAM: Uncharacterised protein family UPF0058; KEGG: mmg:MTBMA_c06730 hypothetical protein.


ensembl_gene_id: Metbo_1369
symbol: cpgS
gene_biotype: protein_coding
description:
  Cyclic 2,3-diphosphoglycerate synthetase; Catalyzes the formation of cyclic 2,3-diphosphoglycerate (cDPG) by formation of an intramolecular phosphoanhydride bond at the expense of ATP.


ensembl_gene_id: Metbo_1370
symbol: ADZ09610.1
gene_biotype: protein_coding
description:
  Thermosome; KEGG: mmg:MTBMA_c06670 thermosome, subunit alpha (chaperonin subunit); TIGRFAM: Thermosome, archaeal; PFAM: Chaperonin Cpn60/TCP-1.


ensembl_gene_id: Metbo_1373
symbol: ADZ09613.1
gene_biotype: protein_coding
description:
  PFAM: Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain; KEGG: mth:MTH1097 hypothetical protein.


ensembl_gene_id: Metbo_1376
symbol: ADZ09616.1
gene_biotype: protein_coding
description:
  PFAM: Transcription regulator, TetR-like, DNA-binding, bacterial/archaeal; KEGG: mpi:Mpet_1090 TetR family transcriptional regulator.


ensembl_gene_id: Metbo_1377
symbol: ADZ09617.1
gene_biotype: protein_coding
description:
  Propanoyl-CoA C-acyltransferase; KEGG: mmg:MTBMA_c11890 acetyl-CoA acetyltransferase; PFAM: Thiolase, C-terminal.


ensembl_gene_id: Metbo_1378
symbol: ADZ09618.1
gene_biotype: protein_coding
description:
  UPF0219 protein; TIGRFAM: Putative condensing enzyme FabH-related; HAMAP: Putative condensing enzyme FabH-related; KEGG: mmg:MTBMA_c11880 3-hydroxy-3-methylglutaryl-CoA-synthase; PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C-terminal; Hydroxymethylglutaryl-coenzyme A synthase, N-terminal; Belongs to the thiolase-like superfamily. UPF0219 family.


ensembl_gene_id: Metbo_1379
symbol: ADZ09619.1
gene_biotype: protein_coding
description:
  PFAM: 5-formyltetrahydrofolate cyclo-ligase; KEGG: mmg:MTBMA_c06530 5-formyltetrahydrofolate cyclo-ligase-related protein.


ensembl_gene_id: Metbo_1381
symbol: ADZ09621.1
gene_biotype: protein_coding
description:
  PFAM: Bacterial bifunctional deaminase-reductase, C-terminal; KEGG: cyh:Cyan8802_0658 bifunctional deaminase-reductase domain protein.


ensembl_gene_id: Metbo_1383
symbol: ogt
gene_biotype: protein_coding
description:
  methylated-DNA/protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.


ensembl_gene_id: Metbo_1385
symbol: ADZ09625.1
gene_biotype: protein_coding
description:
  PFAM: Xanthine/uracil/vitamin C permease; KEGG: mpd:MCP_1361 xanthine/uracil/vitamin C permease family protein.


ensembl_gene_id: Metbo_1390
symbol: ADZ09630.1
gene_biotype: protein_coding
description:
  Protein of unknown function UPF0118; PFAM: Uncharacterised protein family UPF0118; KEGG: mth:MTH1211 hypothetical protein.


ensembl_gene_id: Metbo_1396
symbol: ADZ09636.1
gene_biotype: protein_coding
description:
  KEGG: ptm:GSPATT00039540001 hypothetical protein; PFAM: Tetratricopeptide TPR-1; SMART: Tetratricopeptide repeat.


ensembl_gene_id: Metbo_1399
symbol: ADZ09639.1
gene_biotype: protein_coding
description:
  KEGG: mba:Mbar_A1645 phenylacetic acid degradation protein; TIGRFAM: Phenylacetic acid degradation-related protein; PFAM: Thioesterase superfamily.


ensembl_gene_id: Metbo_1401
symbol: ADZ09641.1
gene_biotype: protein_coding
description:
  PFAM: GCN5-related N-acetyltransferase (GNAT) domain; KEGG: dae:Dtox_1804 GCN5-related N-acetyltransferase.


ensembl_gene_id: Metbo_1408
symbol: ADZ09647.1
gene_biotype: protein_coding
description:
  KEGG: ttr:Tter_2612 drug resistance transporter, EmrB/QacA subfamily; TIGRFAM: Drug resistance transporter EmrB/QacA subfamily; PFAM: Major facilitator superfamily MFS-1.


ensembl_gene_id: Metbo_1409
symbol: ADZ09648.1
gene_biotype: protein_coding
description:
  PFAM: Transcription regulator, TetR-like, DNA-binding, bacterial/archaeal; KEGG: mac:MA0368 TetR family transcriptional regulator.


ensembl_gene_id: Metbo_1411
symbol: ADZ09650.1
gene_biotype: protein_coding
description:
  Beta-lactamase domain protein; KEGG: cdl:CDR20291_0406 putative hydrolase; PFAM: Beta-lactamase-like; SMART: Beta-lactamase-like.


ensembl_gene_id: Metbo_1412
symbol: ADZ09651.1
gene_biotype: protein_coding
description:
  TIGRFAM: PAS; PFAM: Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain; PAS fold-4; PAS fold; PAS fold-3; ATPase-like, ATP-binding domain; KEGG: mac:MA1270 sensory transduction histidine kinase; SMART: ATPase-like, ATP-binding domain; PAS; PAC motif.


ensembl_gene_id: Metbo_1414
symbol: ADZ09653.1
gene_biotype: protein_coding
description:
  PFAM: Rieske [2Fe-2S] iron-sulphur domain; KEGG: nmr:Nmar_0308 Rieske (2Fe-2S) domain-containing protein.


ensembl_gene_id: Metbo_1416
symbol: msrA
gene_biotype: protein_coding
description:
  Peptide methionine sulfoxide reductase msrA; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.


ensembl_gene_id: Metbo_1417
symbol: ADZ09656.1
gene_biotype: protein_coding
description:
  TIGRFAM: PAS; PFAM: Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain; PAS fold; ATPase-like, ATP-binding domain; KEGG: mth:MTH468 sensory transduction histidine kinase; SMART: ATPase-like, ATP-binding domain; PAS.


ensembl_gene_id: Metbo_1419
symbol: ADZ09658.1
gene_biotype: protein_coding
description:
  PHP domain protein; KEGG: mmg:MTBMA_c09400 DNA polymerase IV; PFAM: PHP, C-terminal; SMART: DNA-directed DNA polymerase X; Helix-hairpin-helix DNA-binding motif, class 1; Polymerase/histidinol phosphatase, N-terminal.


ensembl_gene_id: Metbo_1424
symbol: ADZ09662.1
gene_biotype: protein_coding
description:
  TIGRFAM: Glutamate decarboxylase; KEGG: cwo:Cwoe_3467 glutamate decarboxylase; PFAM: Pyridoxal phosphate-dependent decarboxylase.


ensembl_gene_id: Metbo_1427
symbol: ADZ09665.1
gene_biotype: protein_coding
description:
  PFAM: Uncharacterised conserved protein UCP037465, zinc finger protein, AF1427; KEGG: mpi:Mpet_0850 hypothetical protein.


ensembl_gene_id: Metbo_1429
symbol: ADZ09667.1
gene_biotype: protein_coding
description:
  TIGRFAM: PAS; PFAM: Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain; Signal transduction response regulator, receiver domain; PAS fold-3; PAS fold; ATPase-like, ATP-binding domain; KEGG: mac:MA2784 sensory transduction histidine kinase; SMART: Signal transduction response regulator, receiver domain; PAS; PAC motif; ATPase-like, ATP-binding domain.


ensembl_gene_id: Metbo_1430
symbol: ADZ09668.1
gene_biotype: protein_coding
description:
  TIGRFAM: PAS; PFAM: Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain; PAS fold; PAS fold-4; ATPase-like, ATP-binding domain; KEGG: mpl:Mpal_0047 signal transduction histidine kinase; SMART: ATPase-like, ATP-binding domain; PAS; PAC motif.


ensembl_gene_id: Metbo_1431
symbol: ADZ09669.1
gene_biotype: protein_coding
description:
  PFAM: Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain; KEGG: mmg:MTBMA_c00670 hypothetical protein.


ensembl_gene_id: Metbo_1434
symbol: ADZ09672.1
gene_biotype: protein_coding
description:
  Regulatory protein TetR; PFAM: Transcription regulator, TetR-like, DNA-binding, bacterial/archaeal; KEGG: bpb:bpr_III151 TetR family transcriptional regulator.


ensembl_gene_id: Metbo_1436
symbol: ADZ09674.1
gene_biotype: protein_coding
description:
  NADPH dehydrogenase; KEGG: cbt:CLH_2467 oxidoreductase, FAD/FMN-binding; PFAM: NADH:flavin oxidoreductase/NADH oxidase, N-terminal.


ensembl_gene_id: Metbo_1438
symbol: ADZ09676.1
gene_biotype: protein_coding
description:
  KEGG: mif:Metin_0662 TPR repeat-containing protein; PFAM: Tetratricopeptide TPR-1; SMART: Tetratricopeptide repeat.


ensembl_gene_id: Metbo_1442
symbol: ADZ09680.1
gene_biotype: protein_coding
description:
  DsrE family protein; PFAM: Sulphur relay, DsrE/F-like protein; SirA-like; KEGG: mmg:MTBMA_c00060 peroxiredoxin-related protein.


ensembl_gene_id: Metbo_1445
symbol: ADZ09683.1
gene_biotype: protein_coding
description:
  TIGRFAM: PAS; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS fold; KEGG: nde:NIDE1493 putative sensor histidine kinase with MCP region; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS; PAC motif.


ensembl_gene_id: Metbo_1446
symbol: ADZ09684.1
gene_biotype: protein_coding
description:
  Regulatory protein MarR; KEGG: cbi:CLJ_B2136 transcriptional regulator, MarR family; PFAM: HTH transcriptional regulator, MarR; SMART: HTH transcriptional regulator, MarR.


ensembl_gene_id: Metbo_1449
symbol: ADZ09686.1
gene_biotype: protein_coding
description:
  Pirin domain protein; PFAM: Pirin, N-terminal; Pirin, C-terminal; KEGG: ank:AnaeK_1669 pirin domain protein; Belongs to the pirin family.


ensembl_gene_id: Metbo_1453
symbol: ADZ09690.1
gene_biotype: protein_coding
description:
  PFAM: FAD dependent oxidoreductase; 4Fe-4S binding domain; KEGG: mfv:Mfer_0927 glucose-methanol-choline oxidoreductase.


ensembl_gene_id: Metbo_1456
symbol: ADZ09693.1
gene_biotype: protein_coding
description:
  KEGG: mmg:MTBMA_c09230 pyruvate flavodoxin/ferredoxin oxidoreductase, subunit alpha; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, alpha subunit; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain.


ensembl_gene_id: Metbo_1457
symbol: ADZ09694.1
gene_biotype: protein_coding
description:
  TIGRFAM: 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate; KEGG: ppd:Ppro_0548 pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding.


ensembl_gene_id: Metbo_1461
symbol: ADZ09698.1
gene_biotype: protein_coding
description:
  Transcriptional regulator, TrmB; PFAM: Transcription regulator TrmB, N-terminal; KEGG: mmg:MTBMA_c00400 transcriptional regulator.


ensembl_gene_id: Metbo_1472
symbol: htpX-2
gene_biotype: protein_coding
description:
  Protease htpX; KEGG: dth:DICTH_0757 heat shock protein HtpX; HAMAP: Peptidase M48, protease HtpX, putative; PFAM: Peptidase M48; Belongs to the peptidase M48B family.


ensembl_gene_id: Metbo_1475
symbol: ADZ09710.1
gene_biotype: protein_coding
description:
  SMART: ATPase, AAA+ type, core; TIGRFAM: Daunorubicin resistance ABC transporter ATP-binding subunit; KEGG: rci:LRC320 ABC-type transport system, ATPase component; PFAM: ABC transporter-like.


ensembl_gene_id: Metbo_1478
symbol: ADZ09712.1
gene_biotype: protein_coding
description:
  Heat shock protein DnaJ domain protein; KEGG: pfh:PFHG_00645 hypothetical protein similar to chaperone protein J; PFAM: Heat shock protein DnaJ, N-terminal; SMART: Heat shock protein DnaJ, N-terminal.


ensembl_gene_id: Metbo_1481
symbol: ADZ09715.1
gene_biotype: protein_coding
description:
  Helicase A859L; KEGG: ckr:CKR_1765 hypothetical protein; PFAM: Bacteriophage T5, ORF172 DNA-binding; SMART: Bacteriophage T5, ORF172 DNA-binding.


ensembl_gene_id: Metbo_1483
symbol: ADZ09717.1
gene_biotype: protein_coding
description:
  Polymorphic outer membrane protein; KEGG: mmg:MTBMA_c06050 pseudomurein-binding protein; TIGRFAM: Polymorphic membrane protein, Chlamydia; PFAM: Polymorphic membrane protein, Chlamydia.


ensembl_gene_id: Metbo_1487
symbol: ADZ09720.1
gene_biotype: protein_coding
description:
  Phosphonate-transporting ATPase; PFAM: ABC transporter-like; KEGG: mru:mru_1438 ABC transporter ATP-binding protein; SMART: ATPase, AAA+ type, core.


ensembl_gene_id: Metbo_1488
symbol: ADZ09721.1
gene_biotype: protein_coding
description:
  PFAM: Domain of unknown function DUF214, ABC transporter permease; KEGG: mth:MTH695 hypothetical protein.


ensembl_gene_id: Metbo_1491
symbol: ADZ09724.1
gene_biotype: protein_coding
description:
  KEGG: dae:Dtox_2167 beta-lactamase domain protein; PFAM: Beta-lactamase-like; SMART: Beta-lactamase-like.


ensembl_gene_id: Metbo_1498
symbol: ADZ09730.1
gene_biotype: protein_coding
description:
  ATPase-like, ParA/MinD; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.


ensembl_gene_id: Metbo_1509
symbol: ADZ09740.1
gene_biotype: protein_coding
description:
  TIGRFAM: Peptidase S16, archaeal lon homologues; PFAM: Peptidase S16, Lon C-terminal; ATPase, AAA-5; KEGG: mth:MTH785 ATP-dependent protease Lon; SMART: ATPase, AAA+ type, core; Belongs to the peptidase S16 family.


ensembl_gene_id: Metbo_1510
symbol: ADZ09741.1
gene_biotype: protein_coding
description:
  Regulatory protein ArsR; KEGG: geo:Geob_2068 putative transcriptional regulator, ArsR family; PFAM: HTH transcriptional regulator, ArsR; SMART: HTH transcriptional regulator, ArsR.


ensembl_gene_id: Metbo_1511
symbol: ADZ09742.1
gene_biotype: protein_coding
description:
  Conserved repeat domain protein; KEGG: mmg:MTBMA_c06050 pseudomurein-binding protein; TIGRFAM: Domain of unknown function DUF11; Polymorphic membrane protein, Chlamydia; PFAM: Polymorphic membrane protein, Chlamydia.


ensembl_gene_id: Metbo_1514
symbol: ADZ09745.1
gene_biotype: protein_coding
description:
  PAS/PAC sensor signal transduction histidine kinase; TIGRFAM: PAS; PFAM: ATPase-like, ATP-binding domain; PAS fold-3; PAS fold; PAS fold-4; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; KEGG: nmg:Nmag_4101 PAS/PAC sensor signal transduction histidine kinase; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS; PAC motif.


ensembl_gene_id: Metbo_1515
symbol: ADZ09746.1
gene_biotype: protein_coding
description:
  PFAM: Domain of unknown function DUF214, ABC transporter permease; KEGG: mmg:MTBMA_c10830 ABC-type transport system, permease protein.


ensembl_gene_id: Metbo_1517
symbol: ADZ09748.1
gene_biotype: protein_coding
description:
  Regulatory protein ArsR; KEGG: mmg:MTBMA_c00250 transcriptional regulator; PFAM: HTH transcriptional regulator, ArsR; SMART: HTH transcriptional regulator, ArsR.


ensembl_gene_id: Metbo_1520
symbol: ADZ09750.1
gene_biotype: protein_coding
description:
  KEGG: mpl:Mpal_1654 MATE efflux family protein; TIGRFAM: Multi antimicrobial extrusion protein; PFAM: Multi antimicrobial extrusion protein.


ensembl_gene_id: Metbo_1531
symbol: ADZ09761.1
gene_biotype: protein_coding
description:
  Transcriptional regulator, HxlR family; PFAM: Helix-turn-helix, HxlR type; KEGG: mac:MA0414 hypothetical protein.


ensembl_gene_id: Metbo_1534
symbol: ADZ09764.1
gene_biotype: protein_coding
description:
  ATPase, P-type (transporting), HAD superfamily, subfamily IC; SMART: ATPase, P-type cation-transporter, N-terminal; TIGRFAM: ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter; KEGG: mmg:MTBMA_c01010 cation-transporting ATPase; PFAM: ATPase, P-type, ATPase-associated domain; ATPase, P-type cation-transporter, N-terminal; Haloacid dehalogenase-like hydrolase; ATPase, P-type cation-transporter, C-terminal.


ensembl_gene_id: Metbo_1536
symbol: ADZ09766.1
gene_biotype: protein_coding
description:
  KEGG: mba:Mbar_A3737 hypothetical protein; PFAM: Pyrrolo-quinoline quinone repeat; SMART: Pyrrolo-quinoline quinone beta-propeller repeat.


ensembl_gene_id: Metbo_1541
symbol: ADZ09771.1
gene_biotype: protein_coding
description:
  Deoxyguanosinetriphosphate triphosphohydrolase; SMART: Metal-dependent phosphohydrolase, HD domain; manually curated; KEGG: ccb:Clocel_3591 deoxyguanosinetriphosphate triphosphohydrolase; TIGRFAM: Deoxyguanosinetriphosphate triphosphohydrolase; PFAM: Metal-dependent phosphohydrolase, HD subdomain.


ensembl_gene_id: Metbo_1542
symbol: ADZ09772.1
gene_biotype: protein_coding
description:
  KEGG: bbt:BBta_3620 hypothetical protein; TIGRFAM: Conserved hypothetical protein CHP02391; PFAM: Conserved hypothetical protein CHP02391.


ensembl_gene_id: Metbo_1544
symbol: ADZ09774.1
gene_biotype: protein_coding
description:
  PFAM: Ketopantoate reductase ApbA/PanE, C-terminal; Ketopantoate reductase ApbA/PanE, N-terminal; KEGG: pde:Pden_4530 2-dehydropantoate 2-reductase.


ensembl_gene_id: Metbo_1550
symbol: ADZ09778.1
gene_biotype: protein_coding
description:
  TIGRFAM: PAS; PFAM: Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain; PAS fold; ATPase-like, ATP-binding domain; KEGG: mmg:MTBMA_c08420 sensory transduction histidine kinase; SMART: ATPase-like, ATP-binding domain; PAS.


ensembl_gene_id: Metbo_1557
symbol: ADZ09784.1
gene_biotype: protein_coding
description:
  KEGG: mbu:Mbur_2162 helicase-like protein; PFAM: Helicase, C-terminal; Restriction endonuclease, type I, R subunit/Type III, Res subunit; SMART: Helicase, C-terminal; DEAD-like helicase, N-terminal.


ensembl_gene_id: Metbo_1560
symbol: ADZ09787.1
gene_biotype: protein_coding
description:
  PFAM: Domain of unknown function DUF2357; Protein of unknown function DUF524; KEGG: mru:mru_0063 hypothetical protein.


ensembl_gene_id: Metbo_1563
symbol: ADZ09790.1
gene_biotype: protein_coding
description:
  KEGG: ptm:GSPATT00039790001 hypothetical protein; PFAM: Tetratricopeptide TPR2; Tetratricopeptide TPR-1; Uncharacterised protein family UPF0286; SMART: Tetratricopeptide repeat.


ensembl_gene_id: Metbo_1576
symbol: ADZ09803.1
gene_biotype: protein_coding
description:
  KEGG: mst:Msp_1507 putative DNA polymerase; PFAM: DNA-directed DNA polymerase, family B, exonuclease domain; DNA-directed DNA polymerase, family B, conserved region; SMART: DNA-directed DNA polymerase, family B.


ensembl_gene_id: Metbo_1585
symbol: ppk
gene_biotype: protein_coding
description:
  Polyphosphate kinase 1; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP); Belongs to the polyphosphate kinase 1 (PPK1) family.


ensembl_gene_id: Metbo_1587
symbol: ADZ09814.1
gene_biotype: protein_coding
description:
  Phosphonate-transporting ATPase; PFAM: ABC transporter-like; KEGG: pmo:Pmob_0814 ABC transporter related; SMART: ATPase, AAA+ type, core.


ensembl_gene_id: Metbo_1588
symbol: ADZ09815.1
gene_biotype: protein_coding
description:
  PFAM: Domain of unknown function DUF214, ABC transporter permease; KEGG: rci:RCIX2314 ABC-type transport system, permease component.


ensembl_gene_id: Metbo_1589
symbol: ADZ09816.1
gene_biotype: protein_coding
description:
  PFAM: Transcription regulator, TetR-like, DNA-binding, bacterial/archaeal; KEGG: rci:RCIX1190 TetR family transcriptional regulator.


ensembl_gene_id: Metbo_1591
symbol: ADZ09818.1
gene_biotype: protein_coding
description:
  TIGRFAM: PAS; PFAM: Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain; Signal transduction response regulator, receiver domain; PAS fold; GAF; PAS fold-3; ATPase-like, ATP-binding domain; KEGG: cts:Ctha_0145 signal transduction histidine kinase; SMART: Signal transduction response regulator, receiver domain; PAS; PAC motif; ATPase-like, ATP-binding domain.


ensembl_gene_id: Metbo_1592
symbol: ADZ09819.1
gene_biotype: protein_coding
description:
  KEGG: gvi:glr1768 two-component response regulator; PFAM: Signal transduction response regulator, receiver domain; SMART: Signal transduction response regulator, receiver domain.


ensembl_gene_id: Metbo_1593
symbol: ADZ09820.1
gene_biotype: protein_coding
description:
  TIGRFAM: PAS; PFAM: Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain; HAMP linker domain; ATPase-like, ATP-binding domain; KEGG: mmg:MTBMA_c08550 sensory transduction histidine kinase; SMART: HAMP linker domain; ATPase-like, ATP-binding domain.


ensembl_gene_id: Metbo_1595
symbol: ADZ09822.1
gene_biotype: protein_coding
description:
  KEGG: ppm:PPSC2_c0576 permease of the major facilitator superfamily; manually curated; PFAM: Major facilitator superfamily MFS-1.


ensembl_gene_id: Metbo_1597
symbol: ADZ09824.1
gene_biotype: protein_coding
description:
  Cl- channel voltage-gated family protein; PFAM: Chloride channel, voltage gated; KEGG: amr:AM1_2979 Cl-channel, voltage gated.


ensembl_gene_id: Metbo_1600
symbol: ADZ09827.1
gene_biotype: protein_coding
description:
  Conserved repeat domain protein; TIGRFAM: Domain of unknown function DUF11; Polymorphic membrane protein, Chlamydia; PFAM: Bacterial Ig-like, group 1; Polymorphic membrane protein, Chlamydia; KEGG: mru:mru_0723 adhesin-like protein; SMART: Bacterial Ig-like, group 1; Parallel beta-helix repeat.


ensembl_gene_id: Metbo_1607
symbol: ADZ09834.1
gene_biotype: protein_coding
description:
  Methyltransferase; TIGRFAM: S-adenosyl-L-methionine-dependent methyltransferase, putative; KEGG: mac:MA0170 hypothetical protein.


ensembl_gene_id: Metbo_1610
symbol: ADZ09837.1
gene_biotype: protein_coding
description:
  PFAM: Transcription regulator PadR N-terminal-like; KEGG: tpe:Tpen_1595 PadR-like family transcriptional regulator.


ensembl_gene_id: Metbo_1613
symbol: ADZ09840.1
gene_biotype: protein_coding
description:
  PFAM: Polymorphic membrane protein, Chlamydia; KEGG: chl:Chy400_0321 polymorphic outer membrane protein.


ensembl_gene_id: Metbo_1615
symbol: ADZ09842.1
gene_biotype: protein_coding
description:
  Conserved repeat domain protein; TIGRFAM: Domain of unknown function DUF11; Parallel beta-helix repeat-2; PFAM: Domain of unknown function DUF11; Polymorphic membrane protein, Chlamydia; KEGG: abi:Aboo_0648 fibronectin type III domain protein; SMART: Carbohydrate-binding/sugar hydrolysis domain; Parallel beta-helix repeat.


ensembl_gene_id: Metbo_1616
symbol: ADZ09843.1
gene_biotype: protein_coding
description:
  KEGG: mth:MTH1074 hypothetical protein; TIGRFAM: Domain of unknown function DUF11; PFAM: Domain of unknown function DUF11.


ensembl_gene_id: Metbo_1620
symbol: ADZ09847.1
gene_biotype: protein_coding
description:
  Protein of unknown function DUF74; PFAM: Uncharacterised protein family UPF0145; KEGG: mmg:MTBMA_c08970 hypothetical protein.


ensembl_gene_id: Metbo_1621
symbol: ADZ09848.1
gene_biotype: protein_coding
description:
  Chloride peroxidase; KEGG: mpl:Mpal_2171 alpha/beta hydrolase fold protein; PFAM: Alpha/beta hydrolase fold-1.


ensembl_gene_id: Metbo_1622
symbol: ADZ09849.1
gene_biotype: protein_coding
description:
  TIGRFAM: PAS; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; GAF; PAS fold; PAS fold-3; KEGG: npu:Npun_F6362 multi-sensor signal transduction histidine kinase; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; GAF; PAC motif; PAS.


ensembl_gene_id: Metbo_1623
symbol: ADZ09850.1
gene_biotype: protein_coding
description:
  PFAM: Activator of Hsp90 ATPase homologue 1-like; Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: lic:LIC10664 hypothetical protein.


ensembl_gene_id: Metbo_1624
symbol: ADZ09851.1
gene_biotype: protein_coding
description:
  TIGRFAM: PAS; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; GAF; PAS fold; KEGG: mag:amb3689 signal transduction histidine kinase; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS; PAC motif; GAF.


ensembl_gene_id: Metbo_1625
symbol: ADZ09852.1
gene_biotype: protein_coding
description:
  TIGRFAM: PAS; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS fold; KEGG: mac:MA1270 sensory transduction histidine kinase; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS; PAC motif.


ensembl_gene_id: Metbo_1626
symbol: ADZ09853.1
gene_biotype: protein_coding
description:
  UPF0145 protein ybjQ; Manually curated; HAMAP: Uncharacterised protein family UPF0145; KEGG: mmg:MTBMA_c08980 hypothetical protein; PFAM: Uncharacterised protein family UPF0145; Belongs to the UPF0145 family.


ensembl_gene_id: Metbo_1640
symbol: ADZ09866.1
gene_biotype: protein_coding
description:
  KEGG: fjo:Fjoh_3971 hypothetical protein; TIGRFAM: Domain of unknown function DUF11; Polymorphic membrane protein, Chlamydia; PFAM: Domain of unknown function DUF11; Polymorphic membrane protein, Chlamydia.


ensembl_gene_id: Metbo_1649
symbol: ADZ09875.1
gene_biotype: protein_coding
description:
  PFAM: Polymorphic membrane protein, Chlamydia; Pseudomurein-binding repeat; KEGG: mmg:MTBMA_c06050 pseudomurein-binding protein.


ensembl_gene_id: Metbo_1651
symbol: ADZ09877.1
gene_biotype: protein_coding
description:
  CoA-binding domain protein; KEGG: mbu:Mbur_1347 acyl-CoA synthetase; PFAM: CoA-binding; SMART: CoA-binding.


ensembl_gene_id: Metbo_1654
symbol: ADZ09880.1
gene_biotype: protein_coding
description:
  TIGRFAM: Glutamate decarboxylase; KEGG: mba:Mbar_A2744 glutamate decarboxylase; PFAM: Pyridoxal phosphate-dependent decarboxylase.


ensembl_gene_id: Metbo_1655
symbol: ADZ09881.1
gene_biotype: protein_coding
description:
  PFAM: 4Fe-4S binding domain; KEGG: cbi:CLJ_B3654 4Fe-4S ferredoxin, iron-sulfur binding domain protein.


ensembl_gene_id: Metbo_1657
symbol: ADZ09883.1
gene_biotype: protein_coding
description:
  KEGG: cyj:Cyan7822_4279 PBS lyase heat domain-containing protein repeat-containing protein; PFAM: PBS lyase HEAT-like repeat; SMART: PBS lyase HEAT-like repeat.


ensembl_gene_id: Metbo_1660
symbol: ADZ09886.1
gene_biotype: protein_coding
description:
  Taurine-transporting ATPase; PFAM: ABC transporter-like; KEGG: mtp:Mthe_0218 ABC transporter related; SMART: ATPase, AAA+ type, core.


ensembl_gene_id: Metbo_1661
symbol: ADZ09887.1
gene_biotype: protein_coding
description:
  ABC-type transporter, integral membrane subunit; PFAM: Binding-protein-dependent transport systems inner membrane component; KEGG: msi:Msm_0291 nitrate/sulfonate/bicarbonate ABC transporter, permease component, TauC.


ensembl_gene_id: Metbo_1662
symbol: ADZ09888.1
gene_biotype: protein_coding
description:
  TIGRFAM: ABC transporter, substrate-binding protein, aliphatic sulphonates; KEGG: msi:Msm_1469 nitrate/sulfonate/bicarbonate ABC transporter, substrate-binding component, TauA.


ensembl_gene_id: Metbo_1663
symbol: ADZ09889.1
gene_biotype: protein_coding
description:
  Metallophosphoesterase; PFAM: Metallo-dependent phosphatase; KEGG: mfv:Mfer_0486 metallophosphoesterase.


ensembl_gene_id: Metbo_1666
symbol: ADZ09892.1
gene_biotype: protein_coding
description:
  KEGG: npu:Npun_F6362 multi-sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain.


ensembl_gene_id: Metbo_1669
symbol: ADZ09895.1
gene_biotype: protein_coding
description:
  Transcriptional regulator, MarR family; KEGG: mst:Msp_0512 transcriptional regulator; PFAM: HTH transcriptional regulator, MarR; SMART: HTH transcriptional regulator, MarR.


ensembl_gene_id: Metbo_1672
symbol: ADZ09898.1
gene_biotype: protein_coding
description:
  PFAM: Transcription regulator PadR N-terminal-like; KEGG: rci:RCIX2313 PadR family transcriptional regulator.


ensembl_gene_id: Metbo_1675
symbol: ADZ09901.1
gene_biotype: protein_coding
description:
  Metallophosphoesterase; PFAM: Metallo-dependent phosphatase; KEGG: mtp:Mthe_0264 hypothetical protein.


ensembl_gene_id: Metbo_1676
symbol: ADZ09902.1
gene_biotype: protein_coding
description:
  TIGRFAM: PAS; PFAM: Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain; PAS fold; ATPase-like, ATP-binding domain; KEGG: mth:MTH446 sensory transduction regulatory protein; SMART: ATPase-like, ATP-binding domain; PAS.


ensembl_gene_id: Metbo_1678
symbol: ADZ09904.1
gene_biotype: protein_coding
description:
  PFAM: Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain; KEGG: mmg:MTBMA_c08080 FMN-binding protein.


ensembl_gene_id: Metbo_1679
symbol: ADZ09905.1
gene_biotype: protein_coding
description:
  Regulatory protein ArsR; SMART: HTH transcriptional regulator, ArsR; KEGG: mth:MTH864 hypothetical protein.


ensembl_gene_id: Metbo_1680
symbol: ADZ09906.1
gene_biotype: protein_coding
description:
  KEGG: mfv:Mfer_0973 polymorphic outer membrane protein; TIGRFAM: Polymorphic membrane protein, Chlamydia; PFAM: Polymorphic membrane protein, Chlamydia.


ensembl_gene_id: Metbo_1683
symbol: ADZ09909.1
gene_biotype: protein_coding
description:
  KEGG: slp:Slip_0873 transcriptional regulator, MarR family; PFAM: HTH transcriptional regulator, MarR; SMART: HTH transcriptional regulator, MarR.


ensembl_gene_id: Metbo_1685
symbol: ADZ09910.1
gene_biotype: protein_coding
description:
  Geranylgeranylglycerol-phosphate geranylgeranyltransferase; KEGG: rci:LRC477 prenyltransferase; PFAM: UbiA prenyltransferase.


ensembl_gene_id: Metbo_1688
symbol: ADZ09913.1
gene_biotype: protein_coding
description:
  TIGRFAM: Parallel beta-helix repeat-2; Domain of unknown function DUF11; KEGG: msi:Msm_0282 adhesin-like protein.


ensembl_gene_id: Metbo_1689
symbol: ADZ09914.1
gene_biotype: protein_coding
description:
  PFAM: Uncharacterised conserved protein UCP037409, membrane transporter, MTH672; KEGG: mmq:MmarC5_1480 hypothetical protein.


ensembl_gene_id: Metbo_1696
symbol: ADZ09921.1
gene_biotype: protein_coding
description:
  KEGG: ccb:Clocel_3213 beta-lactamase domain-containing protein; PFAM: Beta-lactamase-like; SMART: Beta-lactamase-like.


ensembl_gene_id: Metbo_1697
symbol: ADZ09922.1
gene_biotype: protein_coding
description:
  PFAM: Protein of unknown function DUF457, transmembrane; KEGG: cni:Calni_0952 membrane-bound metal-dependent hydrolase.


ensembl_gene_id: Metbo_1699
symbol: ADZ09924.1
gene_biotype: protein_coding
description:
  Regulatory protein MarR; KEGG: nth:Nther_1956 transcriptional regulator; PFAM: HTH transcriptional regulator, MarR; SMART: HTH transcriptional regulator, MarR.


ensembl_gene_id: Metbo_1700
symbol: ADZ09925.1
gene_biotype: protein_coding
description:
  KEGG: tsi:TSIB_0718 putative transport protein; TIGRFAM: Drug resistance transporter EmrB/QacA subfamily; PFAM: Major facilitator superfamily MFS-1.


ensembl_gene_id: Metbo_1701
symbol: ADZ09926.1
gene_biotype: protein_coding
description:
  Transcriptional regulator NikR, CopG family; PFAM: Transcription factor, NikR, nickel binding C-terminal; CopG-like DNA-binding; KEGG: mmg:MTBMA_c09830 nickel responsive regulator.


ensembl_gene_id: Metbo_1702
symbol: ADZ09927.1
gene_biotype: protein_coding
description:
  ABC-type metal ion transporter, periplasmic subunit; PFAM: ABC transporter metal-binding lipoprotein; KEGG: mfv:Mfer_0061 periplasmic solute binding protein.


ensembl_gene_id: Metbo_1703
symbol: ADZ09928.1
gene_biotype: protein_coding
description:
  Phosphonate-transporting ATPase; PFAM: ABC transporter-like; KEGG: mev:Metev_2087 ABC transporter-like protein; SMART: ATPase, AAA+ type, core.


ensembl_gene_id: Metbo_1704
symbol: ADZ09929.1
gene_biotype: protein_coding
description:
  ABC-type transporter, integral membrane subunit; PFAM: ABC-3; KEGG: mth:MTH606 manganese transport system membrane protein.


ensembl_gene_id: Metbo_1705
symbol: ADZ09930.1
gene_biotype: protein_coding
description:
  NAD(+) diphosphatase; KEGG: cce:Ccel_2937 NUDIX hydrolase; PFAM: NUDIX hydrolase domain; NADH pyrophosphatase-like, N-terminal; Zinc ribbon, NADH pyrophosphatase.


ensembl_gene_id: Metbo_1706
symbol: ADZ09931.1
gene_biotype: protein_coding
description:
  PFAM: Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain; KEGG: geo:Geob_0985 pyridoxamine 5'-phosphate oxidase-related FMN-binding.


ensembl_gene_id: Metbo_1711
symbol: ADZ09935.1
gene_biotype: protein_coding
description:
  YhgE/Pip N-terminal domain protein; KEGG: mmg:MTBMA_c04280 phage infection protein; TIGRFAM: Phage infection protein, YhgE, N-terminal; Phage infection protein, YhgE, C-terminal; PFAM: ABC-2 type transporter.


ensembl_gene_id: Metbo_1712
symbol: ADZ09936.1
gene_biotype: protein_coding
description:
  PFAM: Transcription regulator, TetR-like, DNA-binding, bacterial/archaeal; KEGG: msi:Msm_0094 TetR family transcriptional regulator.


ensembl_gene_id: Metbo_1715
symbol: ADZ09939.1
gene_biotype: protein_coding
description:
  acetate/CoA ligase; PFAM: AMP-dependent synthetase/ligase; manually curated; KEGG: mth:MTH217 acetyl-CoA synthetase; TIGRFAM: Acetate-CoA ligase.


ensembl_gene_id: Metbo_1716
symbol: ADZ09940.1
gene_biotype: protein_coding
description:
  PFAM: NADP-dependent oxidoreductase domain; KEGG: cbf:CLI_1589 aldo/keto reductase family oxidoreductase.


ensembl_gene_id: Metbo_1727
symbol: ADZ09951.1
gene_biotype: protein_coding
description:
  Phosphoesterase PA-phosphatase related protein; KEGG: mma:MM_3128 hypothetical protein; PFAM: Phosphatidic acid phosphatase type 2/haloperoxidase; SMART: Phosphatidic acid phosphatase type 2/haloperoxidase.


ensembl_gene_id: Metbo_1729
symbol: ADZ09953.1
gene_biotype: protein_coding
description:
  Regulatory protein ArsR; KEGG: mth:MTH1438 hypothetical protein; PFAM: HTH transcriptional regulator, ArsR; SMART: HTH transcriptional regulator, ArsR.


ensembl_gene_id: Metbo_1730
symbol: ADZ09954.1
gene_biotype: protein_coding
description:
  PFAM: NADP-dependent oxidoreductase domain; 4Fe-4S binding domain; KEGG: mac:MA2292 aldo/keto reductase.


ensembl_gene_id: Metbo_1731
symbol: ADZ09955.1
gene_biotype: protein_coding
description:
  PFAM: Transcription regulator, TetR-like, DNA-binding, bacterial/archaeal; KEGG: mvo:Mvol_0570 transcriptional regulator, TetR family.


ensembl_gene_id: Metbo_1736
symbol: ADZ09960.1
gene_biotype: protein_coding
description:
  Regulatory protein TetR; PFAM: Transcription regulator, TetR-like, DNA-binding, bacterial/archaeal; KEGG: hor:Hore_13530 transcriptional regulator, TetR family.


ensembl_gene_id: Metbo_1737
symbol: ADZ09961.1
gene_biotype: protein_coding
description:
  Regulatory protein TetR; PFAM: Transcription regulator, TetR-like, DNA-binding, bacterial/archaeal; KEGG: csc:Csac_2191 TetR family transcriptional regulator.


ensembl_gene_id: Metbo_1742
symbol: ADZ09965.1
gene_biotype: protein_coding
description:
  Manually curated; PFAM: Signal transduction response regulator, receiver domain; KEGG: rci:RCIX2113 putative signal transduction protein; SMART: Signal transduction response regulator, receiver domain.


ensembl_gene_id: Metbo_1744
symbol: ADZ09967.1
gene_biotype: protein_coding
description:
  KEGG: mbn:Mboo_0387 beta-lactamase domain-containing protein; PFAM: Beta-lactamase-like; SMART: Beta-lactamase-like.


ensembl_gene_id: Metbo_1748
symbol: ADZ09971.1
gene_biotype: protein_coding
description:
  MtN3 and saliva related transmembrane protein; PFAM: RAG1-activating protein-1-related; KEGG: dwi:Dwil_GK23163 GK23163 gene product from transcript GK23163-RA.


ensembl_gene_id: Metbo_1749
symbol: ADZ09972.1
gene_biotype: protein_coding
description:
  Glutamine--fructose-6-phosphate transaminase (isomerizing); KEGG: mth:MTH860 glucosamine--fructose-6-phosphate aminotransferase; PFAM: Sugar isomerase (SIS).


ensembl_gene_id: Metbo_1751
symbol: gap
gene_biotype: protein_coding
description:
  KEGG: mth:MTH1009 glyceraldehyde-3-phosphate dehydrogenase; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; TIGRFAM: Glyceraldehyde-3-phosphate dehydrogenase, type II; HAMAP: Glyceraldehyde-3-phosphate dehydrogenase; SMART: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain.


ensembl_gene_id: Metbo_1752
symbol: ADZ09975.1
gene_biotype: protein_coding
description:
  Nitrite reductase (NAD(P)H); KEGG: mba:Mbar_A3664 hypothetical protein; PFAM: Nitrite/sulphite reductase 4Fe-4S domain; Nitrite/sulphite reductase, hemoprotein beta-component, ferrodoxin-like.


ensembl_gene_id: Metbo_1755
symbol: ADZ09978.1
gene_biotype: protein_coding
description:
  TIGRFAM: PAS; PFAM: Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain; PAS fold-3; GAF; PAS fold; PAS fold-4; ATPase-like, ATP-binding domain; KEGG: mac:MA0551 sensory transduction histidine kinase; SMART: ATPase-like, ATP-binding domain; PAS; PAC motif.


ensembl_gene_id: Metbo_1758
symbol: ADZ09981.1
gene_biotype: protein_coding
description:
  PFAM: Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal; UspA; KEGG: mbn:Mboo_0896 osmosensitive K+ channel His kinase sensor.


ensembl_gene_id: Metbo_1759
symbol: kdpC
gene_biotype: protein_coding
description:
  Potassium-transporting ATPase C chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.


ensembl_gene_id: Metbo_1760
symbol: kdpB
gene_biotype: protein_coding
description:
  Potassium-transporting ATPase B chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.


ensembl_gene_id: Metbo_1761
symbol: kdpA
gene_biotype: protein_coding
description:
  Potassium-transporting ATPase A chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane.


ensembl_gene_id: Metbo_1762
symbol: ADZ09985.1
gene_biotype: protein_coding
description:
  PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: cby:CLM_0738 lactoylglutathione lyase.


ensembl_gene_id: Metbo_1780
symbol: tfb
gene_biotype: protein_coding
description:
  Transcription initiation factor IIB; Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).


ensembl_gene_id: Metbo_1783
symbol: ADZ10005.1
gene_biotype: protein_coding
description:
  TIGRFAM: PAS; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS fold; KEGG: mac:MA1270 sensory transduction histidine kinase; SMART: ATPase-like, ATP-binding domain; PAS; PAC motif; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain.


ensembl_gene_id: Metbo_1784
symbol: ADZ10006.1
gene_biotype: protein_coding
description:
  PFAM: Biotin-protein ligase, N-terminal; Pseudomurein-binding repeat; KEGG: mfv:Mfer_0615 hypothetical protein.


ensembl_gene_id: Metbo_1788
symbol: ADZ10010.1
gene_biotype: protein_coding
description:
  PFAM: Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain; KEGG: mba:Mbar_A3327 hypothetical protein.


ensembl_gene_id: Metbo_1797
symbol: ADZ10019.1
gene_biotype: protein_coding
description:
  KEGG: mth:MTH357 hypothetical protein; PFAM: Transglutaminase-like; Pseudomurein-binding repeat; SMART: Transglutaminase-like.


ensembl_gene_id: Metbo_1808
symbol: tfe
gene_biotype: protein_coding
description:
  Transcription factor E; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems  [...]


ensembl_gene_id: Metbo_1809
symbol: ADZ10031.1
gene_biotype: protein_coding
description:
  APHP domain protein; PFAM: APHP; Succinylglutamate desuccinylase/aspartoacylase; KEGG: mka:MK1596 aminoacylase-2/carboxypeptidase Z family hydrolase.


ensembl_gene_id: Metbo_1814
symbol: ADZ10036.1
gene_biotype: protein_coding
description:
  PFAM: Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain; KEGG: mba:Mbar_A1549 antibiotic resistance protein.


ensembl_gene_id: Metbo_1816
symbol: ADZ10038.1
gene_biotype: protein_coding
description:
  PFAM: Nitrogenase/oxidoreductase, component 1; KEGG: cts:Ctha_1833 Fe-only nitrogenase subunit beta; Belongs to the NifD/NifK/NifE/NifN family.


ensembl_gene_id: Metbo_1817
symbol: ADZ10039.1
gene_biotype: protein_coding
description:
  TIGRFAM: Nitrogenase iron-iron, delta subunit; KEGG: ckr:CKR_0321 hypothetical protein; PFAM: Vanadium/alternative nitrogenase delta subunit.


ensembl_gene_id: Metbo_1818
symbol: ADZ10040.1
gene_biotype: protein_coding
description:
  TIGRFAM: Nitrogenase iron-iron protein, alpha chain; Nitrogenase alpha chain; Nitrogenase component 1, alpha chain; KEGG: cts:Ctha_1831 nitrogenase subunit alpha; PFAM: Nitrogenase/oxidoreductase, component 1.


ensembl_gene_id: Metbo_1819
symbol: nifH
gene_biotype: protein_coding
description:
  Nitrogenase iron protein; The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein; Belongs to the NifH/BchL/ChlL family.


ensembl_gene_id: Metbo_1822
symbol: ADZ10044.1
gene_biotype: protein_coding
description:
  PFAM: Heat shock protein Hsp20; Late embryogenesis abundant protein, group 4; KEGG: mth:MTH859 heat shock protein, class I; Belongs to the small heat shock protein (HSP20) family.


ensembl_gene_id: Metbo_1834
symbol: ADZ10056.1
gene_biotype: protein_coding
description:
  Tetratricopeptide TPR_1 repeat-containing protein; KEGG: ter:Tery_3996 tetratricopeptide TPR_2; PFAM: Tetratricopeptide TPR-1; Tetratricopeptide TPR2; SMART: Tetratricopeptide repeat.


ensembl_gene_id: Metbo_1835
symbol: ADZ10057.1
gene_biotype: protein_coding
description:
  Aspartate 4-decarboxylase; KEGG: sna:Snas_3840 aminotransferase class I and II; TIGRFAM: Aspartate 4-decarboxylase; PFAM: Aminotransferase, class I/classII.


ensembl_gene_id: Metbo_1836
symbol: ADZ10058.1
gene_biotype: protein_coding
description:
  Pseudomurein-binding repeat-containing protein; PFAM: Pseudomurein-binding repeat; KEGG: msi:Msm_0219 cysteine protease.


ensembl_gene_id: Metbo_1841
symbol: ADZ10063.1
gene_biotype: protein_coding
description:
  RQC domain-containing protein; KEGG: clj:CLJU_c25260 putative ATP-dependent DNA helicase; PFAM: RQC domain; SMART: RQC domain.


ensembl_gene_id: Metbo_1846
symbol: ADZ10068.1
gene_biotype: protein_coding
description:
  TIGRFAM: PAS; PFAM: Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain; PAS fold; ATPase-like, ATP-binding domain; KEGG: rci:RCIX1713 putative signal transduction histidine kinase; SMART: ATPase-like, ATP-binding domain; PAS; PAC motif.


ensembl_gene_id: Metbo_1858
symbol: ADZ10079.1
gene_biotype: protein_coding
description:
  Transcriptional regulator, ArsR family; KEGG: mmg:MTBMA_c12940 transcriptional regulator; PFAM: HTH transcriptional regulator, ArsR; SMART: HTH transcriptional regulator, ArsR.


ensembl_gene_id: Metbo_1860
symbol: ADZ10081.1
gene_biotype: protein_coding
description:
  Manually curated; PFAM: Protein-tyrosine phosphatase, low molecular weight; KEGG: dth:DICTH_0400 arsenate reductase; SMART: Protein-tyrosine phosphatase, low molecular weight.


ensembl_gene_id: Metbo_1862
symbol: ADZ10083.1
gene_biotype: protein_coding
description:
  KEGG: rrs:RoseRS_1917 arsenical-resistance protein; TIGRFAM: Arsenical-resistance protein ACR3; PFAM: Bile acid:sodium symporter.


ensembl_gene_id: Metbo_1865
symbol: ADZ10086.1
gene_biotype: protein_coding
description:
  TIGRFAM: PAS; PFAM: Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain; CHASE4; HAMP linker domain; PAS fold; ATPase-like, ATP-binding domain; KEGG: mmg:MTBMA_c08420 sensory transduction histidine kinase; SMART: ATPase-like, ATP-binding domain; PAS.


ensembl_gene_id: Metbo_1869
symbol: ADZ10090.1
gene_biotype: protein_coding
description:
  Response regulator receiver protein; KEGG: mma:MM_2516 putative transcriptional regulator; PFAM: Signal transduction response regulator, receiver domain; SMART: Signal transduction response regulator, receiver domain.


ensembl_gene_id: Metbo_1872
symbol: ADZ10093.1
gene_biotype: protein_coding
description:
  Putative PAS/PAC sensor protein; TIGRFAM: PAS; PFAM: PAS fold-3; PAS fold-4; PAS fold; KEGG: sfu:Sfum_2638 signal transduction histidine kinase; SMART: PAS; PAC motif.


ensembl_gene_id: Metbo_1873
symbol: ADZ10094.1
gene_biotype: protein_coding
description:
  DEAD/H associated domain protein; KEGG: mth:MTH1802 ATP-dependent helicase; PFAM: DEAD/H associated; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; Helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; ATPase, AAA+ type, core; Helicase, C-terminal.


ensembl_gene_id: Metbo_1874
symbol: ADZ10095.1
gene_biotype: protein_coding
description:
  Phosphoesterase; KEGG: mmg:MTBMA_c03740 phosphoesterase; TIGRFAM: Conserved hypothetical protein CHP00024; PFAM: Metallo-dependent phosphatase.


ensembl_gene_id: Metbo_1880
symbol: ADZ10101.1
gene_biotype: protein_coding
description:
  PBS lyase HEAT domain protein repeat-containing protein; PFAM: PBS lyase HEAT-like repeat; KEGG: mth:MTH1806 phycocyanin alpha phycocyanobilin lyase CpcE.


ensembl_gene_id: Metbo_1881
symbol: ADZ10102.1
gene_biotype: protein_coding
description:
  PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: mru:mru_0603 N-carbamoyl-D-amino acid amidohydrolase AguB.


ensembl_gene_id: Metbo_1884
symbol: ADZ10105.1
gene_biotype: protein_coding
description:
  KEGG: mfv:Mfer_0531 atpase associated with various cellular activities aaa_5; PFAM: ATPase, AAA-5; SMART: ATPase, AAA+ type, core.


ensembl_gene_id: Metbo_1887
symbol: ADZ10107.1
gene_biotype: protein_coding
description:
  Metallophosphoesterase; PFAM: Metallo-dependent phosphatase; KEGG: mfv:Mfer_1284 metallophosphoesterase.


ensembl_gene_id: Metbo_1888
symbol: ADZ10108.1
gene_biotype: protein_coding
description:
  PFAM: Major facilitator superfamily MFS-1; KEGG: mpi:Mpet_1795 major facilitator superfamily protein.


ensembl_gene_id: Metbo_1889
symbol: ADZ10109.1
gene_biotype: protein_coding
description:
  ABC-type transporter, periplasmic subunit family 3; SMART: Extracellular solute-binding protein, family 3; KEGG: mfv:Mfer_0616 aliphatic sulfonates family abc transporter, periplasmic ligand-binding protein.


ensembl_gene_id: Metbo_1890
symbol: nucS
gene_biotype: protein_coding
description:
  UPF0286 protein; Cleaves both 3' and 5' ssDNA extremities of branched DNA structures; Belongs to the NucS endonuclease family.


ensembl_gene_id: Metbo_1891
symbol: ADZ10111.1
gene_biotype: protein_coding
description:
  Cobalamin B12-binding domain protein; PFAM: Cobalamin (vitamin B12)-binding; KEGG: mmh:Mmah_0910 cobalamin B12-binding domain protein.


ensembl_gene_id: Metbo_1893
symbol: ADZ10113.1
gene_biotype: protein_coding
description:
  PFAM: Glucose-methanol-choline oxidoreductase, N-terminal; FAD dependent oxidoreductase; KEGG: mfv:Mfer_0927 glucose-methanol-choline oxidoreductase.


ensembl_gene_id: Metbo_1895
symbol: ADZ10115.1
gene_biotype: protein_coding
description:
  KEGG: mmg:MTBMA_c12950 sensory transduction histidine kinase; PFAM: Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain; Signal transduction response regulator, receiver domain; ATPase-like, ATP-binding domain; PAS fold; SMART: Signal transduction response regulator, receiver domain; ATPase-like, ATP-binding domain.


ensembl_gene_id: Metbo_1896
symbol: ADZ10116.1
gene_biotype: protein_coding
description:
  TIGRFAM: PAS; PFAM: Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain; PAS fold-3; Signal transduction response regulator, receiver domain; ATPase-like, ATP-binding domain; KEGG: mth:MTH902 sensory transduction histidine kinase; SMART: Signal transduction response regulator, receiver domain; ATPase-like, ATP-binding domain.


ensembl_gene_id: Metbo_1898
symbol: ADZ10118.1
gene_biotype: protein_coding
description:
  TIGRFAM: Acetate-CoA ligase; KEGG: mfv:Mfer_0074 acetyl-coenzyme a synthetase; PFAM: AMP-dependent synthetase/ligase.


ensembl_gene_id: Metbo_1901
symbol: ADZ10121.1
gene_biotype: protein_coding
description:
  Thermosome; KEGG: mth:MTH794 chaperonin; TIGRFAM: Thermosome, archaeal; PFAM: Chaperonin Cpn60/TCP-1.


ensembl_gene_id: Metbo_1904
symbol: asd
gene_biotype: protein_coding
description:
  Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.


ensembl_gene_id: Metbo_1905
symbol: dapB
gene_biotype: protein_coding
description:
  Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.


ensembl_gene_id: Metbo_1906
symbol: dapA
gene_biotype: protein_coding
description:
  Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).


ensembl_gene_id: Metbo_1907
symbol: ADZ10127.1
gene_biotype: protein_coding
description:
  KEGG: mmg:MTBMA_c11980 aspartate kinase; TIGRFAM: Aspartate kinase domain; Aspartate kinase, monofunctional class; PFAM: Aspartate/glutamate/uridylate kinase; Amino acid-binding ACT; Belongs to the aspartokinase family.


ensembl_gene_id: Metbo_1908
symbol: rps17e
gene_biotype: protein_coding
description:
  KEGG: msi:Msm_0833 30S ribosomal protein S17e; HAMAP: Ribosomal protein S17e; PFAM: Ribosomal protein S17e; Belongs to the eukaryotic ribosomal protein eS17 family.


ensembl_gene_id: Metbo_1909
symbol: ADZ10129.1
gene_biotype: protein_coding
description:
  TIGRFAM: Chorismate mutase, archaeal; PFAM: Chorismate mutase, type II; KEGG: mfv:Mfer_0679 chorismate mutase, type II; SMART: Chorismate mutase.


ensembl_gene_id: Metbo_1910
symbol: aroK
gene_biotype: protein_coding
description:
  PFAM: GHMP kinase; GHMP kinase, C-terminal; TIGRFAM: Shikimate kinase, archaea; HAMAP: Shikimate kinase; KEGG: mfv:Mfer_0680 shikimate kinase.


ensembl_gene_id: Metbo_1911
symbol: ADZ10131.1
gene_biotype: protein_coding
description:
  Signal peptide peptidase SppA, 36K type; KEGG: mth:MTH806 protease IV; TIGRFAM: Peptidase S49, SppA; PFAM: Peptidase S49.


ensembl_gene_id: Metbo_1912
symbol: ADZ10132.1
gene_biotype: protein_coding
description:
  Redox-active disulfide protein 1; KEGG: mmg:MTBMA_c12030 thioredoxin; TIGRFAM: Thioredoxins/glutaredoxin; PFAM: Glutaredoxin.


ensembl_gene_id: Metbo_1913
symbol: cbiD
gene_biotype: protein_coding
description:
  cobalt-precorrin-6A synthase (deacetylating); Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.


ensembl_gene_id: Metbo_1914
symbol: moaC
gene_biotype: protein_coding
description:
  Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.


ensembl_gene_id: Metbo_1915
symbol: hel308
gene_biotype: protein_coding
description:
  DEAD/DEAH box helicase domain protein; DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks.


ensembl_gene_id: Metbo_1916
symbol: ADZ10136.1
gene_biotype: protein_coding
description:
  PFAM: Protein of unknown function DUF2115; KEGG: msi:Msm_0367 hypothetical protein; Belongs to the UPF0305 family.


ensembl_gene_id: Metbo_1917
symbol: ADZ10137.1
gene_biotype: protein_coding
description:
  PFAM: Protein of unknown function DUF2115; KEGG: mth:MTH812 hypothetical protein; Belongs to the UPF0305 family.


ensembl_gene_id: Metbo_1925
symbol: ADZ10145.1
gene_biotype: protein_coding
description:
  Peptidase M50; KEGG: mth:MTH816 sporulation protein IVFB related protein; PFAM: Peptidase M50; Cystathionine beta-synthase, core; SMART: Cystathionine beta-synthase, core; Belongs to the peptidase M50B family.


ensembl_gene_id: Metbo_1926
symbol: ADZ10146.1
gene_biotype: protein_coding
description:
  Histone acetyltransferase, ELP3 family; SMART: Elongator protein 3/MiaB/NifB; TIGRFAM: Histone acetyltransferase ELP3; KEGG: mst:Msp_0372 histone acetyltransferase; PFAM: Radical SAM; GCN5-related N-acetyltransferase (GNAT) domain.


ensembl_gene_id: Metbo_1927
symbol: deoC
gene_biotype: protein_coding
description:
  Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.


ensembl_gene_id: Metbo_1929
symbol: ADZ10149.1
gene_biotype: protein_coding
description:
  PFAM: GCN5-related N-acetyltransferase (GNAT) domain; KEGG: gym:GYMC10_0929 GCN5-related N-acetyltransferase.


ensembl_gene_id: Metbo_1930
symbol: ADZ10150.1
gene_biotype: protein_coding
description:
  Regulatory protein MarR; KEGG: mma:MM_1903 MarR family transcriptional regulator; PFAM: HTH transcriptional regulator, MarR; SMART: HTH transcriptional regulator, MarR.


ensembl_gene_id: Metbo_1931
symbol: cofH-2
gene_biotype: protein_coding
description:
  FO synthase subunit 2; Catalyzes the radical-mediated synthesis of 5-amino-5-(4- hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil from 5-amino-6-(D- ribitylamino)uracil and L-tyrosine.


ensembl_gene_id: Metbo_1932
symbol: ADZ10152.1
gene_biotype: protein_coding
description:
  Transcription factor CBF/NF-Y/histone domain-containing protein; PFAM: Transcription factor CBF/NF-Y/archaeal histone; KEGG: mth:MTH821 histone HMtA1.


ensembl_gene_id: Metbo_1937
symbol: ADZ10157.1
gene_biotype: protein_coding
description:
  Regulatory protein MarR; KEGG: bsu:BSU04770 putative transcriptional regulator; PFAM: HTH transcriptional regulator, MarR; SMART: HTH transcriptional regulator, MarR.


ensembl_gene_id: Metbo_1938
symbol: ADZ10158.1
gene_biotype: protein_coding
description:
  PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: mpl:Mpal_1261 glyoxalase/bleomycin resistance protein/dioxygenase.


ensembl_gene_id: Metbo_1941
symbol: ADZ10161.1
gene_biotype: protein_coding
description:
  TIGRFAM: Methylthiotransferase; MiaB-like tRNA modifying enzyme, archaeal-type; PFAM: Methylthiotransferase, N-terminal; Radical SAM; Deoxyribonuclease/rho motif-related TRAM; KEGG: mth:MTH826 hypothetical protein; SMART: Elongator protein 3/MiaB/NifB.


ensembl_gene_id: Metbo_1942
symbol: pcm
gene_biotype: protein_coding
description:
  Protein-L-isoaspartate O-methyltransferase; Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.


ensembl_gene_id: Metbo_1944
symbol: hacB
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydratase small subunit; Hydro-lyase with broad substrate specificity for cis- unsaturated tricarboxylic acids. Catalyzes both the reversible dehydration of (R)-homocitrate ((R)-2-hydroxybutane-1,2,4- tricarboxylate) to produce cis-homoaconitate ((Z)-but-1-ene-1,2,4- tricarboxylate), and its hydration to homoisocitrate ((1R,2S)-1- hydroxybutane-1,2,4-tricarboxylate). Is also able to hydrate the analogous longer chain substrates cis-homo(2)-aconitate, cis-homo(3)- aconitate. All these reactions are part of the biosynthesis pathway of coenzyme B; Belongs to the LeuD f [...]


ensembl_gene_id: Metbo_1945
symbol: ADZ10165.1
gene_biotype: protein_coding
description:
  Beta-ribofuranosylaminobenzene 5'-phosphate synthase family; Catalyzes the condensation of 4-aminobenzoate (pABA) with 5- phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta- ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P).


ensembl_gene_id: Metbo_1947
symbol: carS
gene_biotype: protein_coding
description:
  UPF0290 protein; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids.


ensembl_gene_id: Metbo_1948
symbol: ADZ10168.1
gene_biotype: protein_coding
description:
  H4MPT-linked C1 transfer pathway protein; KEGG: mth:MTH834 hypothetical protein; TIGRFAM: Tetrahydromethanopterin-linked C1 transfer pathway, putative; PFAM: Hydantoinase/oxoprolinase.


ensembl_gene_id: Metbo_1950
symbol: ADZ10170.1
gene_biotype: protein_coding
description:
  TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; KEGG: mth:MTH837 UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase.


ensembl_gene_id: Metbo_1952
symbol: truA
gene_biotype: protein_coding
description:
  tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs; Belongs to the tRNA pseudouridine synthase TruA family.


ensembl_gene_id: Metbo_1953
symbol: ADZ10173.1
gene_biotype: protein_coding
description:
  Protein of unknown function DUF6 transmembrane; PFAM: Drug/metabolite transporter; KEGG: mth:MTH841 hypothetical protein.


ensembl_gene_id: Metbo_1954
symbol: hisA
gene_biotype: protein_coding
description:
  1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino) imidazole-4-carboxamide isomerase; PFAM: Histidine biosynthesis; TIGRFAM: Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA; HAMAP: Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; KEGG: mmg:MTBMA_c12400 phosphoribosylformimino-5-aminoimidazole ribonucleotide isomerase.


ensembl_gene_id: Metbo_1957
symbol: ribL
gene_biotype: protein_coding
description:
  Cytidyltransferase-related domain protein; Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme.


ensembl_gene_id: Metbo_1958
symbol: ADZ10178.1
gene_biotype: protein_coding
description:
  TIGRFAM: Polymorphic membrane protein, Chlamydia; PFAM: PKD domain; Pyrrolo-quinoline quinone repeat; Polymorphic membrane protein, Chlamydia; KEGG: mac:MA1762 cell surface protein; SMART: PKD/Chitinase domain; Pyrrolo-quinoline quinone beta-propeller repeat; Parallel beta-helix repeat.


ensembl_gene_id: Metbo_1959
symbol: ADZ10179.1
gene_biotype: protein_coding
description:
  PFAM: Phosphomethylpyrimidine kinase; Histidine triad (HIT) protein; KEGG: mmg:MTBMA_c12580 phosphomethylpyrimidine kinase.


ensembl_gene_id: Metbo_1962
symbol: ADZ10182.1
gene_biotype: protein_coding
description:
  Small GTP-binding protein; KEGG: mmg:MTBMA_c12550 GTPase; TIGRFAM: Small GTP-binding protein; PFAM: GTP-binding protein, HSR1-related.


ensembl_gene_id: Metbo_1963
symbol: ADZ10183.1
gene_biotype: protein_coding
description:
  TIGRFAM: AMMECR1; HAMAP: AMMECR1-domain protein; KEGG: mru:mru_1728 AMMECR1 domain-containing protein; PFAM: AMMECR1.


ensembl_gene_id: Metbo_1965
symbol: ADZ10185.1
gene_biotype: protein_coding
description:
  Protein of unknown function DUF39; KEGG: mmg:MTBMA_c12520 CBS domain containing protein; PFAM: Domain of unknown function DUF39; Cystathionine beta-synthase, core; SMART: Cystathionine beta-synthase, core.


ensembl_gene_id: Metbo_1966
symbol: ADZ10186.1
gene_biotype: protein_coding
description:
  NIL domain-containing protein; KEGG: mmg:MTBMA_c12510 conserved hypothetical protein containing a ferredoxin domain; PFAM: NIL domain; 4Fe-4S binding domain; SMART: NIL domain.


ensembl_gene_id: Metbo_1971
symbol: ecfA
gene_biotype: protein_coding
description:
  Cobalt ABC transporter, ATPase subunit; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.


ensembl_gene_id: Metbo_1974
symbol: pyrF
gene_biotype: protein_coding
description:
  Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.


ensembl_gene_id: Metbo_1976
symbol: ADZ10196.1
gene_biotype: protein_coding
description:
  TIGRFAM: Deoxyhypusine synthase; KEGG: mth:MTH127 deoxyhypusine synthase; PFAM: Deoxyhypusine synthase.


ensembl_gene_id: Metbo_1977
symbol: ADZ10197.1
gene_biotype: protein_coding
description:
  Putative signal transduction protein with CBS domains; KEGG: mth:MTH126 inosine-5'-monophosphate dehydrogenase related protein VII; PFAM: Winged helix-turn-helix transcription repressor, HrcA DNA-binding domain; Cystathionine beta-synthase, core; SMART: Cystathionine beta-synthase, core.


ensembl_gene_id: Metbo_1979
symbol: ADZ10199.1
gene_biotype: protein_coding
description:
  Xenobiotic-transporting ATPase; PFAM: ABC transporter-like; ABC transporter, transmembrane domain; KEGG: lsp:Bsph_0315 putative multidrug export ATP-binding/permease protein; SMART: ATPase, AAA+ type, core.


ensembl_gene_id: Metbo_1983
symbol: ADZ10203.1
gene_biotype: protein_coding
description:
  Radical SAM domain protein; KEGG: mth:MTH1784 Mg-protoporphyrin IX monomethyl ester oxidative cyclase; PFAM: Radical SAM; Cobalamin (vitamin B12)-binding; SMART: Elongator protein 3/MiaB/NifB.


ensembl_gene_id: Metbo_2006
symbol: ADZ10225.1
gene_biotype: protein_coding
description:
  KEGG: mba:Mbar_A3349 flavoredoxin Flr; PFAM: Flavin reductase-like, FMN-binding; SMART: Flavin reductase-like, FMN-binding.


ensembl_gene_id: Metbo_2008
symbol: ADZ10227.1
gene_biotype: protein_coding
description:
  UPF0597 protein yhaM; HAMAP: Uncharacterised protein family UPF0597; KEGG: ckr:CKR_0543 hypothetical protein; Belongs to the UPF0597 family.


ensembl_gene_id: Metbo_2019
symbol: ADZ10238.1
gene_biotype: protein_coding
description:
  Regulatory protein ArsR; PFAM: HTH transcriptional regulator, ArsR; KEGG: mth:MTH1438 hypothetical protein.


ensembl_gene_id: Metbo_2029
symbol: ADZ10248.1
gene_biotype: protein_coding
description:
  PFAM: Protein of unknown function DUF2085, transmembrane; KEGG: mmg:MTBMA_c09070 hypothetical protein.


ensembl_gene_id: Metbo_2031
symbol: ADZ10250.1
gene_biotype: protein_coding
description:
  KEGG: cvi:CV_1162 peptide ABC transporter; TIGRFAM: Amino acid/peptide transporter; PFAM: Oligopeptide transporter.


ensembl_gene_id: Metbo_2036
symbol: ADZ10255.1
gene_biotype: protein_coding
description:
  Acetolactate synthase; KEGG: mth:MTH476 pyruvate dehydrogenase / acetolactate synthase; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding; Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain; Rubredoxin-type Fe(Cys)4 protein; Thiamine pyrophosphate enzyme, central domain.


ensembl_gene_id: Metbo_2037
symbol: ADZ10256.1
gene_biotype: protein_coding
description:
  KEGG: mmg:MTBMA_c02450 glutamate synthase, alpha subunit related protein; PFAM: Glutamate synthase, central-C; Belongs to the glutamate synthase family.


ensembl_gene_id: Metbo_2039
symbol: ADZ10258.1
gene_biotype: protein_coding
description:
  PUA domain containing protein; KEGG: mst:Msp_1063 RNA-binding protein; PFAM: Pseudouridine synthase/archaeosine transglycosylase; SMART: Pseudouridine synthase/archaeosine transglycosylase.


ensembl_gene_id: Metbo_2042
symbol: trpD
gene_biotype: protein_coding
description:
  Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).


ensembl_gene_id: Metbo_2043
symbol: trpA
gene_biotype: protein_coding
description:
  Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.


ensembl_gene_id: Metbo_2045
symbol: trpF
gene_biotype: protein_coding
description:
  PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); KEGG: mfv:Mfer_0095 phosphoribosylanthranilate isomerase; Belongs to the TrpF family.


ensembl_gene_id: Metbo_2046
symbol: ADZ10265.1
gene_biotype: protein_coding
description:
  KEGG: mfv:Mfer_0096 indole-3-glycerol-phosphate synthase; PFAM: Indole-3-glycerol phosphate synthase.


ensembl_gene_id: Metbo_2047
symbol: ADZ10266.1
gene_biotype: protein_coding
description:
  TIGRFAM: Anthranilate synthase, glutamine amidotransferase domain; KEGG: mfv:Mfer_0097 anthranilate synthase, component II; PFAM: Glutamine amidotransferase class-I, C-terminal.


ensembl_gene_id: Metbo_2048
symbol: trpE
gene_biotype: protein_coding
description:
  Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...]


ensembl_gene_id: Metbo_2050
symbol: ADZ10269.1
gene_biotype: protein_coding
description:
  Hydrogenase assembly chaperone hypC/hupF; KEGG: mmg:MTBMA_c02320 hydrogenase maturation factor HypC; TIGRFAM: Hydrogenase expression/formation protein, HupF/HypC; PFAM: Hydrogenase expression/formation protein, HupF/HypC.


ensembl_gene_id: Metbo_2051
symbol: ADZ10270.1
gene_biotype: protein_coding
description:
  KEGG: mst:Msp_1077 dihydrolipoamide dehydrogenase-related protein; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase.


ensembl_gene_id: Metbo_2052
symbol: ADZ10271.1
gene_biotype: protein_coding
description:
  PFAM: Formylmethanofuran dehydrogenase, subunit E domain; KEGG: mac:MA4602 formylmethanofuran dehydrogenase, subunit E.


ensembl_gene_id: Metbo_2056
symbol: ADZ10275.1
gene_biotype: protein_coding
description:
  Sulfate-transporting ATPase; PFAM: ABC transporter-like; KEGG: mpd:MCP_0256 ABC transporter ATP binding protein; SMART: ATPase, AAA+ type, core.


ensembl_gene_id: Metbo_2060
symbol: pelA
gene_biotype: protein_coding
description:
  Pelota-like protein; May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity.


ensembl_gene_id: Metbo_2061
symbol: ADZ10280.1
gene_biotype: protein_coding
description:
  Putative PAS/PAC sensor protein; TIGRFAM: PAS; PFAM: Signal transduction response regulator, receiver domain; PAS fold-4; KEGG: gur:Gura_1549 multi-sensor signal transduction histidine kinase; SMART: Signal transduction response regulator, receiver domain; PAS; PAC motif.


ensembl_gene_id: Metbo_2062
symbol: ADZ10281.1
gene_biotype: protein_coding
description:
  Conserved repeat domain protein; TIGRFAM: Domain of unknown function DUF11; KEGG: gur:Gura_1160 hypothetical protein.


ensembl_gene_id: Metbo_2064
symbol: ADZ10283.1
gene_biotype: protein_coding
description:
  SMART: ATPase, AAA+ type, core; TIGRFAM: ATPase, AAA-type, CDC48; KEGG: mth:MTH1639 cell division control protein Cdc48; PFAM: ATPase, AAA-type, core; ATPase, AAA-type, VAT, N-terminal; Cell division protein 48, CDC48, domain 2.


ensembl_gene_id: Metbo_2065
symbol: ADZ10284.1
gene_biotype: protein_coding
description:
  Adenosylhomocysteinase; Catalyzes the hydrolysis of S-inosyl-L-homocysteine (SIH) to L-homocysteine (Hcy) and inosine. Likely functions in a S-adenosyl-L- methionine (SAM) recycling pathway from S-adenosyl-L-homocysteine (SAH) produced from SAM-dependent methylation reactions. Can also catalyze the reverse reaction in vitro, i.e. the synthesis of SIH from Hcy and inosine; Belongs to the adenosylhomocysteinase family.


ensembl_gene_id: Metbo_2068
symbol: fen
gene_biotype: protein_coding
description:
  Flap structure-specific endonuclease; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair [...]


ensembl_gene_id: Metbo_2071
symbol: ADZ10290.1
gene_biotype: protein_coding
description:
  TIGRFAM: Isopropylmalate/citramalate/homocitrate synthase; KEGG: mmg:MTBMA_c02150 2-isopropylmalate synthase; PFAM: Pyruvate carboxyltransferase; Belongs to the alpha-IPM synthase/homocitrate synthase family.


ensembl_gene_id: Metbo_2072
symbol: ADZ10291.1
gene_biotype: protein_coding
description:
  Adenylyl cyclase CyaB; KEGG: mmg:MTBMA_c02140 adenylate cyclase; TIGRFAM: Adenylyl cyclase CyaB; PFAM: Adenylate cyclase.


ensembl_gene_id: Metbo_2074
symbol: tbp
gene_biotype: protein_coding
description:
  TATA-box-binding protein; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.


ensembl_gene_id: Metbo_2075
symbol: ADZ10294.1
gene_biotype: protein_coding
description:
  TIGRFAM: Phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB, PSPase-like; KEGG: mru:mru_0388 phosphoserine phosphatase SerB; PFAM: Haloacid dehalogenase-like hydrolase.


ensembl_gene_id: Metbo_2076
symbol: rad50
gene_biotype: protein_coding
description:
  SMC domain protein; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex; Belongs to the SMC family. RAD50 subfamily.


ensembl_gene_id: Metbo_2077
symbol: mre11
gene_biotype: protein_coding
description:
  Metallophosphoesterase; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity. Belongs to the MRE11/RAD32 family.


ensembl_gene_id: Metbo_2078
symbol: ADZ10297.1
gene_biotype: protein_coding
description:
  PFAM: Domain of unknown function DUF87; HerA-ATP synthase, barrel domain; KEGG: mru:mru_1104 ATPase.


ensembl_gene_id: Metbo_2083
symbol: ADZ10302.1
gene_biotype: protein_coding
description:
  TIGRFAM: UDP-glucose 4-epimerase; KEGG: mth:MTH631 UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase.


ensembl_gene_id: Metbo_2084
symbol: ADZ10303.1
gene_biotype: protein_coding
description:
  TIGRFAM: UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal type; KEGG: mmg:MTBMA_c10160 UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase.


ensembl_gene_id: Metbo_2085
symbol: ADZ10304.1
gene_biotype: protein_coding
description:
  TIGRFAM: dTDP-glucose 4,6-dehydratase; KEGG: mst:Msp_1114 dTDP-D-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase.


ensembl_gene_id: Metbo_2086
symbol: ADZ10305.1
gene_biotype: protein_coding
description:
  UPF0235 protein yggU; TIGRFAM: Conserved hypothetical protein CHP00251; HAMAP: Protein of unknown function DUF167; KEGG: mmg:MTBMA_c10190 hypothetical protein; PFAM: Protein of unknown function DUF167; Belongs to the UPF0235 family.


ensembl_gene_id: Metbo_2087
symbol: ADZ10306.1
gene_biotype: protein_coding
description:
  KEGG: pjd:Pjdr2_6008 major facilitator superfamily MFS_1; PFAM: Major facilitator superfamily MFS-1; Cystathionine beta-synthase, core; SMART: Cystathionine beta-synthase, core.


ensembl_gene_id: Metbo_2088
symbol: ADZ10307.1
gene_biotype: protein_coding
description:
  Regulatory protein MarR; KEGG: ppy:PPE_01803 transcriptional regulator; PFAM: HTH transcriptional regulator, MarR; SMART: HTH transcriptional regulator, MarR.


ensembl_gene_id: Metbo_2091
symbol: ADZ10310.1
gene_biotype: protein_coding
description:
  KEGG: dae:Dtox_1747 beta-lactamase domain protein; PFAM: Beta-lactamase-like; SMART: Beta-lactamase-like.


ensembl_gene_id: Metbo_2092
symbol: ADZ10311.1
gene_biotype: protein_coding
description:
  KEGG: mst:Msp_1119 hypothetical protein; PFAM: Protein of unknown function DUF123; SMART: Excinuclease ABC, C subunit, N-terminal.


ensembl_gene_id: Metbo_2094
symbol: ADZ10313.1
gene_biotype: protein_coding
description:
  CBS domain containing membrane protein; KEGG: mth:MTH644 hypothetical protein; PFAM: Cystathionine beta-synthase, core; SMART: Cystathionine beta-synthase, core.


ensembl_gene_id: Metbo_2095
symbol: ADZ10314.1
gene_biotype: protein_coding
description:
  Regulatory protein MarR; KEGG: bcy:Bcer98_2823 MarR family transcriptional regulator; PFAM: HTH transcriptional regulator, MarR; SMART: HTH transcriptional regulator, MarR.


ensembl_gene_id: Metbo_2098
symbol: purF
gene_biotype: protein_coding
description:
  Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.


ensembl_gene_id: Metbo_2100
symbol: rpl37e
gene_biotype: protein_coding
description:
  50S ribosomal protein L37e; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL37 family.


ensembl_gene_id: Metbo_2101
symbol: ADZ10320.1
gene_biotype: protein_coding
description:
  snRNP Sm-like protein; SMART: Like-Sm ribonucleoprotein (LSM) domain, eukaryotic/archaea-type; manually curated; HAMAP: snRNP Sm-like, putative, archaea; KEGG: mst:Msp_1175 small nuclear ribonucleoprotein; PFAM: Like-Sm ribonucleoprotein (LSM) domain; Belongs to the snRNP Sm proteins family.


ensembl_gene_id: Metbo_2102
symbol: ADZ10321.1
gene_biotype: protein_coding
description:
  Universal PUA-domain-containing protein; TIGRFAM: Conserved hypothetical protein CHP03684; Uncharacterised domain 2; PFAM: Pseudouridine synthase/archaeosine transglycosylase; KEGG: mth:MTH650 putative RNA-binding protein; SMART: Pseudouridine synthase/archaeosine transglycosylase.


ensembl_gene_id: Metbo_2104
symbol: ADZ10323.1
gene_biotype: protein_coding
description:
  KEGG: mst:Msp_1178 helicase; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; Helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; Helicase, C-terminal.


ensembl_gene_id: Metbo_2105
symbol: ADZ10324.1
gene_biotype: protein_coding
description:
  Long-chain-fatty-acid--CoA ligase; KEGG: mth:MTH657 AMP-binding domain protein; PFAM: AMP-dependent synthetase/ligase.


ensembl_gene_id: Metbo_2107
symbol: ADZ10326.1
gene_biotype: protein_coding
description:
  KEGG: mmz:MmarC7_1587 helix-turn-helix domain-containing protein; PFAM: Helix-turn-helix type 3; Cupin 2, conserved barrel; SMART: Helix-turn-helix type 3.


ensembl_gene_id: Metbo_2109
symbol: glmS
gene_biotype: protein_coding
description:
  Glucosamine--fructose-6-phosphate aminotransferase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.


ensembl_gene_id: Metbo_2110
symbol: ADZ10329.1
gene_biotype: protein_coding
description:
  (S)-2-hydroxy-acid oxidase; KEGG: dat:HRM2_41110 FMN-dependent dehydrogenase family protein (TIM barrel family protein); PFAM: Rubredoxin-type Fe(Cys)4 protein; FMN-dependent dehydrogenase.


ensembl_gene_id: Metbo_2112
symbol: ADZ10331.1
gene_biotype: protein_coding
description:
  TIGRFAM: Succinate dehydrogenase/fumarate reductase iron-sulphur protein; KEGG: mmh:Mmah_0726 succinate dehydrogenase and fumarate reductase iron-sulfur protein; PFAM: Ferredoxin.


ensembl_gene_id: Metbo_2113
symbol: ADZ10332.1
gene_biotype: protein_coding
description:
  TIGRFAM: Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; KEGG: mmh:Mmah_0725 succinate dehydrogenase subunit A; PFAM: Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal; Fumarate reductase/succinate dehydrogenase flavoprotein, C-terminal.


ensembl_gene_id: Metbo_2114
symbol: purC
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase; TIGRFAM: SAICAR synthetase; HAMAP: SAICAR synthetase; KEGG: mth:MTH170 phosphoribosylaminoimidazole-succinocarboxamide synthase.


ensembl_gene_id: Metbo_2115
symbol: purS
gene_biotype: protein_coding
description:
  Phosphoribosylformylglycinamidine synthase, purS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assi [...]


ensembl_gene_id: Metbo_2116
symbol: purQ
gene_biotype: protein_coding
description:
  Phosphoribosylformylglycinamidine synthase 1; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...]


ensembl_gene_id: Metbo_2117
symbol: ADZ10336.1
gene_biotype: protein_coding
description:
  TIGRFAM: Uroporphyrin-III C-methyltransferase, C-terminal; KEGG: mru:mru_1541 uroporphyrin-III C-methyltransferase CobA; PFAM: Tetrapyrrole methylase.


ensembl_gene_id: Metbo_2118
symbol: ADZ10337.1
gene_biotype: protein_coding
description:
  KEGG: mfv:Mfer_1298 uroporphyrinogen III synthase HEM4; PFAM: Tetrapyrrole biosynthesis, uroporphyrinogen III synthase.


ensembl_gene_id: Metbo_2119
symbol: srp19
gene_biotype: protein_coding
description:
  Signal recognition particle 19 kDa protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP.


ensembl_gene_id: Metbo_2121
symbol: ADZ10340.1
gene_biotype: protein_coding
description:
  Regulatory protein Crp; SMART: HTH transcriptional regulator, Crp; KEGG: mst:Msp_1188 transcriptional regulator.


ensembl_gene_id: Metbo_2123
symbol: ADZ10342.1
gene_biotype: protein_coding
description:
  PHP domain protein; Manually curated; PFAM: PHP, C-terminal; KEGG: mst:Msp_1186 hypothetical protein; SMART: Polymerase/histidinol phosphatase, N-terminal.


ensembl_gene_id: Metbo_2125
symbol: ADZ10344.1
gene_biotype: protein_coding
description:
  TIGRFAM: Riboflavin-specific deaminase, C-terminal; 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1-reductase, archaeal; KEGG: mmg:MTBMA_c06840 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1-reductase; PFAM: Bacterial bifunctional deaminase-reductase, C-terminal.


ensembl_gene_id: Metbo_2126
symbol: ADZ10345.1
gene_biotype: protein_coding
description:
  PFAM: Carboxymuconolactone decarboxylase; KEGG: sml:Smlt1304 putative 4-carboxymuconolactone decarboxylase.


ensembl_gene_id: Metbo_2127
symbol: ADZ10346.1
gene_biotype: protein_coding
description:
  KEGG: mfv:Mfer_0596 hydrolase, TatD family; TIGRFAM: Deoxyribonuclease, TatD Mg-dependent, prokaryote; PFAM: Deoxyribonuclease, TatD-related.


ensembl_gene_id: Metbo_2128
symbol: uppS
gene_biotype: protein_coding
description:
  Undecaprenyl pyrophosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids.


ensembl_gene_id: Metbo_2129
symbol: ADZ10348.1
gene_biotype: protein_coding
description:
  Methanogen marker protein 4; TIGRFAM: Methyltransferase Mtx, subunit X; KEGG: mfv:Mfer_0594 methanogen marker protein 4.


ensembl_gene_id: Metbo_2131
symbol: hemL
gene_biotype: protein_coding
description:
  Glutamate-1-semialdehyde 2,1-aminomutase; PFAM: Aminotransferase class-III; TIGRFAM: Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase; HAMAP: Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase; KEGG: mfv:Mfer_0593 glutamate-1-semialdehyde 2,1-aminomutase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.


ensembl_gene_id: Metbo_2132
symbol: ADZ10351.1
gene_biotype: protein_coding
description:
  Chloramphenicol O-acetyltransferase; KEGG: mma:MM_2214 polysaccharide ABC transporter ATP-binding protein.


ensembl_gene_id: Metbo_2133
symbol: ADZ10352.1
gene_biotype: protein_coding
description:
  Precorrin-8X methylmutase CbiC/CobH; PFAM: Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase, core; KEGG: mst:Msp_1179 precorrin-8X methylmutase.


ensembl_gene_id: Metbo_2136
symbol: ADZ10355.1
gene_biotype: protein_coding
description:
  PFAM: Carboxymuconolactone decarboxylase; KEGG: mmg:MTBMA_c10790 carboxymuconolactone decarboxylase related protein.


ensembl_gene_id: Metbo_2142
symbol: ADZ10359.1
gene_biotype: protein_coding
description:
  PFAM: Protein of unknown function DUF2284, metal-binding; KEGG: sfu:Sfum_2843 metal-binding protein-like.


ensembl_gene_id: Metbo_2143
symbol: ADZ10360.1
gene_biotype: protein_coding
description:
  Transcriptional regulator, TrmB; KEGG: mth:MTH1454 hypothetical protein; manually curated; PFAM: Transcription regulator TrmB, N-terminal.


ensembl_gene_id: Metbo_2149
symbol: ADZ10365.1
gene_biotype: protein_coding
description:
  PFAM: Protein of unknown function DUF1802; KEGG: mth:MTH1210 mrr restriction system related protein.


ensembl_gene_id: Metbo_2153
symbol: ADZ10368.1
gene_biotype: protein_coding
description:
  Type II site-specific deoxyribonuclease; KEGG: abi:Aboo_1333 protein of unknown function DUF450; PFAM: Restriction endonuclease, type I, EcoRI, R subunit/Type III, Res subunit, N-terminal; DNA methylase, adenine-specific.


ensembl_gene_id: Metbo_2157
symbol: ADZ10372.1
gene_biotype: protein_coding
description:
  KEGG: bcg:BCG9842_B5359 P4 family phage/plasmid primase; TIGRFAM: DNA primase, phage/plasmid; PFAM: Phage/plasmid primase, P4, C-terminal.


ensembl_gene_id: Metbo_2159
symbol: ADZ10374.1
gene_biotype: protein_coding
description:
  KEGG: gur:Gura_1160 hypothetical protein; TIGRFAM: Polymorphic membrane protein, Chlamydia; PFAM: Polymorphic membrane protein, Chlamydia.


ensembl_gene_id: Metbo_2164
symbol: ADZ10379.1
gene_biotype: protein_coding
description:
  Integrase family protein; PFAM: Integrase, catalytic core, phage; KEGG: mac:MA2582 hypothetical protein.


ensembl_gene_id: Metbo_2165
symbol: ADZ10380.1
gene_biotype: protein_coding
description:
  PFAM: Domain of unknown function DUF214, ABC transporter permease; KEGG: clj:CLJU_c15500 putative ABC transporter permease.


ensembl_gene_id: Metbo_2166
symbol: ADZ10381.1
gene_biotype: protein_coding
description:
  KEGG: afu:AF1469 ABC transporter, ATP-binding protein; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core.


ensembl_gene_id: Metbo_2168
symbol: ADZ10383.1
gene_biotype: protein_coding
description:
  KEGG: mth:MTH205 hydrogenase expression/formation protein HypE; TIGRFAM: Hydrogenase expression/formation protein HypE; PFAM: AIR synthase-related protein, C-terminal; AIR synthase-related protein.


ensembl_gene_id: Metbo_2170
symbol: rps8e
gene_biotype: protein_coding
description:
  TIGRFAM: Ribosomal protein S8e; HAMAP: Ribosomal protein S8e, archaeal; KEGG: mth:MTH207 30S ribosomal protein S8e; PFAM: Ribosomal protein S8e/ribosomal biogenesis NSA2.


ensembl_gene_id: Metbo_2171
symbol: ADZ10386.1
gene_biotype: protein_coding
description:
  KEGG: mfv:Mfer_0221 replicative DNA polymerase I; PFAM: DNA-directed DNA polymerase, family B, conserved region.


ensembl_gene_id: Metbo_2172
symbol: ADZ10387.1
gene_biotype: protein_coding
description:
  KEGG: mth:MTH209 hypothetical protein; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, CTE7; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase-like hydrolase.


ensembl_gene_id: Metbo_2177
symbol: ADZ10392.1
gene_biotype: protein_coding
description:
  PFAM: Histidine biosynthesis; KEGG: mru:mru_1337 HisA/HisF family protein HisAF; Belongs to the HisA/HisF family.


ensembl_gene_id: Metbo_2179
symbol: pfdB
gene_biotype: protein_coding
description:
  Prefoldin subunit beta; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.


ensembl_gene_id: Metbo_2182
symbol: ADZ10397.1
gene_biotype: protein_coding
description:
  RNA polymerase Rbp10; KEGG: mmg:MTBMA_c10670 DNA-directed RNA polymerase II, subunit RPC10; manually curated; SMART: RNA polymerase Rbp10.


ensembl_gene_id: Metbo_2184
symbol: rrp42
gene_biotype: protein_coding
description:
  3' exoribonuclease; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site.


ensembl_gene_id: Metbo_2185
symbol: rrp41
gene_biotype: protein_coding
description:
  Exosome complex exonuclease 1; Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'->5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails.


ensembl_gene_id: Metbo_2187
symbol: ADZ10401.1
gene_biotype: protein_coding
description:
  Shwachman-Bodian-Diamond syndrome protein; KEGG: mth:MTH685 putative RNA-associated protein; TIGRFAM: Ribosome maturation protein SBDS; PFAM: Ribosome maturation protein SBDS, N-terminal; Ribosome maturation protein SBDS, C-terminal.


ensembl_gene_id: Metbo_2188
symbol: psmA
gene_biotype: protein_coding
description:
  Proteasome subunit alpha; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.


ensembl_gene_id: Metbo_2189
symbol: rnp2
gene_biotype: protein_coding
description:
  Ribonuclease P protein component 2; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 2 family.


ensembl_gene_id: Metbo_2190
symbol: rnp3
gene_biotype: protein_coding
description:
  Ribonuclease P protein component 3; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 3 family.


ensembl_gene_id: Metbo_2191
symbol: ADZ10405.1
gene_biotype: protein_coding
description:
  Protein of unknown function DUF54; PFAM: Uncharacterised protein family UPF0201; KEGG: mfv:Mfer_0818 hypothetical protein.


ensembl_gene_id: Metbo_2192
symbol: rpl15e
gene_biotype: protein_coding
description:
  KEGG: mmg:MTBMA_c10770 50S ribosomal protein L15e; HAMAP: Ribosomal protein L15e, archaeal; PFAM: Ribosomal protein L15e; Belongs to the eukaryotic ribosomal protein eL15 family.


ensembl_gene_id: Metbo_2194
symbol: ADZ10408.1
gene_biotype: protein_coding
description:
  TIGRFAM: Riboflavin synthase, archaeal; KEGG: mst:Msp_1239 riboflavin synthase; PFAM: 6,7-dimethyl-8-ribityllumazine synthase.


ensembl_gene_id: Metbo_2195
symbol: mch
gene_biotype: protein_coding
description:
  Methenyltetrahydromethanopterin cyclohydrolase; Catalyzes the reversible interconversion of 5-formyl-H(4)MPT to methenyl-H(4)MPT(+); Belongs to the MCH family.


ensembl_gene_id: Metbo_2196
symbol: thyA
gene_biotype: protein_coding
description:
  Thymidylate synthase, methanogen type; May catalyze the biosynthesis of dTMP using an unknown cosubstrate; Belongs to the thymidylate synthase family. Archaeal-type ThyA subfamily.


ensembl_gene_id: Metbo_2201
symbol: ADZ10415.1
gene_biotype: protein_coding
description:
  KEGG: mmg:MTBMA_c11780 hydrogenase maturation factor HypB; TIGRFAM: Hydrogenase accessory protein HypB; PFAM: Cobalamin (vitamin B12) biosynthesis CobW-like.


ensembl_gene_id: Metbo_2202
symbol: hypA
gene_biotype: protein_coding
description:
  Hydrogenase nickel incorporation protein hypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.


ensembl_gene_id: Metbo_2203
symbol: prs
gene_biotype: protein_coding
description:
  Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P).


ensembl_gene_id: Metbo_2205
symbol: ADZ10419.1
gene_biotype: protein_coding
description:
  KEGG: mst:Msp_1228 helicase; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; Helicase, C-terminal; DbpA, RNA-binding; SMART: DEAD-like helicase, N-terminal; Helicase, C-terminal; Belongs to the DEAD box helicase family.


ensembl_gene_id: Metbo_2207
symbol: cobQ
gene_biotype: protein_coding
description:
  Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.


ensembl_gene_id: Metbo_2209
symbol: ADZ10423.1
gene_biotype: protein_coding
description:
  Putative signal transduction protein with CBS domains; KEGG: mmg:MTBMA_c11350 CBS domain containing protein; PFAM: Cystathionine beta-synthase, core; SMART: Cystathionine beta-synthase, core.


ensembl_gene_id: Metbo_2210
symbol: ADZ10424.1
gene_biotype: protein_coding
description:
  Transcriptional regulator NikR, CopG family; Transcriptional regulator; Belongs to the transcriptional regulatory CopG/NikR family.


ensembl_gene_id: Metbo_2212
symbol: ADZ10426.1
gene_biotype: protein_coding
description:
  KEGG: mmg:MTBMA_c11320 hydrogenase maturation protease; TIGRFAM: Peptidase A31, hydrogenase maturation protease HycI; Peptidase A31, hydrogen uptake protein; PFAM: Peptidase A31, hydrogen uptake protein.


ensembl_gene_id: Metbo_2214
symbol: ADZ10428.1
gene_biotype: protein_coding
description:
  KEGG: mth:MTH735 phospho-N-acetylmuramoyl-pentapeptide-transferase; PFAM: Glycosyl transferase, family 4; Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site.


ensembl_gene_id: Metbo_2215
symbol: ADZ10429.1
gene_biotype: protein_coding
description:
  Mur ligase middle domain protein; PFAM: Mur ligase, central; Mur ligase, C-terminal; KEGG: mfv:Mfer_0762 mur ligase middle domain protein.


ensembl_gene_id: Metbo_2217
symbol: ADZ10431.1
gene_biotype: protein_coding
description:
  Mur ligase middle domain protein; PFAM: Mur ligase, central; Mur ligase, C-terminal; KEGG: msi:Msm_1190 UDP-N-acetylmuramate-alanine ligase.


ensembl_gene_id: Metbo_2221
symbol: ADZ10435.1
gene_biotype: protein_coding
description:
  Transcriptional regulator, XRE family; TIGRFAM: Conserved hypothetical protein CHP00270; PFAM: Helix-turn-helix type 3; KEGG: mmg:MTBMA_c11250 transcriptional regulator; SMART: Helix-turn-helix type 3.


ensembl_gene_id: Metbo_2222
symbol: pan
gene_biotype: protein_coding
description:
  Proteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase- [...]


ensembl_gene_id: Metbo_2223
symbol: ADZ10437.1
gene_biotype: protein_coding
description:
  Precorrin-6x reductase; KEGG: mst:Msp_1205 CbiJ; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobK/CbiJ, precorrin-6x reductase; PFAM: Cobalamin (vitamin B12) biosynthesis CobK/CbiJ, precorrin-6x reductase.


ensembl_gene_id: Metbo_2224
symbol: ADZ10438.1
gene_biotype: protein_coding
description:
  SMART: ATPase, P-type cation-transporter, N-terminal; TIGRFAM: ATPase, P-type, calcium-transporting, PMCA-type; ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter; KEGG: mmg:MTBMA_c13830 cation transport ATPase; PFAM: ATPase, P-type, ATPase-associated domain; ATPase, P-type cation-transporter, N-terminal; Haloacid dehalogenase-like hydrolase; ATPase, P-type cation-transporter, C-terminal.


ensembl_gene_id: Metbo_2225
symbol: ADZ10439.1
gene_biotype: protein_coding
description:
  Protein of unknown function UPF0146; PFAM: Uncharacterised protein family UPF0146; KEGG: mmg:MTBMA_c13820 hypothetical protein; Belongs to the UPF0146 family.


ensembl_gene_id: Metbo_2226
symbol: ADZ10440.1
gene_biotype: protein_coding
description:
  KEGG: mth:MTH999 N-terminal acetyltransferase complex, subunit ARD1; TIGRFAM: Ribosomal-protein-alanine acetyltransferase; PFAM: GCN5-related N-acetyltransferase (GNAT) domain.


ensembl_gene_id: Metbo_2227
symbol: carA
gene_biotype: protein_coding
description:
  TIGRFAM: Carbamoyl-phosphate synthase, small subunit; KEGG: mmg:MTBMA_c13800 carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase, small subunit, N-terminal; Glutamine amidotransferase class-I, C-terminal; Belongs to the CarA family.


ensembl_gene_id: Metbo_2228
symbol: carB
gene_biotype: protein_coding
description:
  SMART: Methylglyoxal synthase-like domain; TIGRFAM: Carbamoyl-phosphate synthase, large subunit; KEGG: mmg:MTBMA_c13790 carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthetase, large subunit, ATP-binding; Carbamoyl-phosphate synthase, large subunit, N-terminal; Carbamoyl-phosphate synthetase, large subunit, oligomerisation; Methylglyoxal synthase-like domain; Belongs to the CarB family.


ensembl_gene_id: Metbo_2230
symbol: serS
gene_biotype: protein_coding
description:
  Seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).


ensembl_gene_id: Metbo_2232
symbol: ADZ10446.1
gene_biotype: protein_coding
description:
  Putative signal transduction protein with CBS domains; KEGG: mth:MTH992 inosine-5'-monophosphate dehydrogenase related protein IX; PFAM: Cystathionine beta-synthase, core; SMART: Cystathionine beta-synthase, core.


ensembl_gene_id: Metbo_2238
symbol: ADZ10452.1
gene_biotype: protein_coding
description:
  Metal dependent phosphohydrolase; TIGRFAM: HD-related protein; Uncharacterised protein family HDIG; PFAM: Metal-dependent phosphohydrolase, HD subdomain; KEGG: mru:mru_0474 HD domain-containing protein; SMART: Metal-dependent phosphohydrolase, HD domain.


ensembl_gene_id: Metbo_2240
symbol: ADZ10454.1
gene_biotype: protein_coding
description:
  Protein of unknown function DUF129; PFAM: F420-0 gamma-glutamyl ligase-related; KEGG: mth:MTH1670 hypothetical protein.


ensembl_gene_id: Metbo_2243
symbol: ADZ10457.1
gene_biotype: protein_coding
description:
  ABC transporter related protein; KEGG: mth:MTH1673 sn-glycerol-3-phosphate transport ATP-binding protein; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core.


ensembl_gene_id: Metbo_2244
symbol: ADZ10458.1
gene_biotype: protein_coding
description:
  TIGRFAM: Phosphosulpholactate synthase; KEGG: mth:MTH1674 hypothetical protein; PFAM: (2R)-phospho-3-sulpholactate synthase, ComA.


ensembl_gene_id: Metbo_2247
symbol: ftsZ
gene_biotype: protein_coding
description:
  Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.


ensembl_gene_id: Metbo_2248
symbol: secE
gene_biotype: protein_coding
description:
  Preprotein translocase subunit secE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.


ensembl_gene_id: Metbo_2249
symbol: spt5
gene_biotype: protein_coding
description:
  NusG antitermination factor; Stimulates transcription elongation; Belongs to the archaeal Spt5 family.


ensembl_gene_id: Metbo_2250
symbol: rpl11
gene_biotype: protein_coding
description:
  Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family.


ensembl_gene_id: Metbo_2252
symbol: rpl10
gene_biotype: protein_coding
description:
  Acidic ribosomal protein P0-like protein; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.


ensembl_gene_id: Metbo_2253
symbol: rpl12
gene_biotype: protein_coding
description:
  50S ribosomal protein L12P; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the eukaryotic ribosomal protein P1/P2 family.


ensembl_gene_id: Metbo_2254
symbol: alaS
gene_biotype: protein_coding
description:
  alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.


ensembl_gene_id: Metbo_2256
symbol: ADZ10470.1
gene_biotype: protein_coding
description:
  KEGG: mth:MTH1684 hypothetical protein; TIGRFAM: Putative methanogenesis marker 16 metalloprotein; PFAM: Domain of unknown function DUF39; 4Fe-4S binding domain.


ensembl_gene_id: Metbo_2263
symbol: ADZ10477.1
gene_biotype: protein_coding
description:
  KEGG: mmg:MTBMA_c14600 hydrogenase expression/formation protein HypD; TIGRFAM: Hydrogenase formation HypD protein; PFAM: Hydrogenase formation HypD protein.


ensembl_gene_id: Metbo_2264
symbol: ADZ10478.1
gene_biotype: protein_coding
description:
  KEGG: mfv:Mfer_0340 mur ligase middle domain protein; PFAM: Mur ligase, central; Mur ligase, C-terminal.


ensembl_gene_id: Metbo_2269
symbol: ADZ10483.1
gene_biotype: protein_coding
description:
  Geranylgeranylglyceryl phosphate synthase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids.


ensembl_gene_id: Metbo_2270
symbol: rpl40e
gene_biotype: protein_coding
description:
  HAMAP: 50S ribosomal protein L40e; KEGG: mmg:MTBMA_c09420 50S ribosomal protein L40E; Belongs to the eukaryotic ribosomal protein eL40 family.


ensembl_gene_id: Metbo_2271
symbol: ADZ10485.1
gene_biotype: protein_coding
description:
  UPF0293 protein; Probable pre-rRNA processing protein involved in ribosome biogenesis; Belongs to the TSR3 family.


ensembl_gene_id: Metbo_2273
symbol: ADZ10487.1
gene_biotype: protein_coding
description:
  Magnesium chelatase; PFAM: von Willebrand factor, type A; ATPase, AAA-5; KEGG: mmg:MTBMA_c09440 cobaltochelatase subunit-like protein; SMART: von Willebrand factor, type A; ATPase, AAA+ type, core.


ensembl_gene_id: Metbo_2278
symbol: ADZ10492.1
gene_biotype: protein_coding
description:
  TIGRFAM: Methyl-coenzyme M reductase, beta subunit; KEGG: mfv:Mfer_0731 methyl-coenzyme m reductase, beta subunit; PFAM: Methyl-coenzyme M reductase, beta subunit, C-terminal; Methyl-coenzyme M reductase, beta subunit, N-terminal.


ensembl_gene_id: Metbo_2279
symbol: ADZ10493.1
gene_biotype: protein_coding
description:
  KEGG: mst:Msp_0319 MrtD; TIGRFAM: Methyl-coenzyme M reductase, protein D; PFAM: Methyl-coenzyme M reductase, protein D.


ensembl_gene_id: Metbo_2280
symbol: ADZ10494.1
gene_biotype: protein_coding
description:
  TIGRFAM: Methyl-coenzyme M reductase, gamma subunit; KEGG: mth:MTH1130 methyl coenzyme M reductase II, gamma subunit; PFAM: Methyl-coenzyme M reductase, gamma subunit.


ensembl_gene_id: Metbo_2282
symbol: ADZ10496.1
gene_biotype: protein_coding
description:
  PFAM: Transcription regulator, TetR-like, DNA-binding, bacterial/archaeal; KEGG: mac:MA2764 TetR family transcriptional regulator.


ensembl_gene_id: Metbo_2283
symbol: ADZ10497.1
gene_biotype: protein_coding
description:
  PFAM: MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal; MCP methyltransferase, CheR-type, all-alpha domain, N-terminal; KEGG: mbn:Mboo_0327 putative PAS/PAC sensor protein; SMART: MCP methyltransferase, CheR-type.


ensembl_gene_id: Metbo_2284
symbol: ADZ10498.1
gene_biotype: protein_coding
description:
  TIGRFAM: PAS; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS fold; PAS fold-3; PAS fold-4; KEGG: mac:MA1270 sensory transduction histidine kinase; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAC motif; PAS.


ensembl_gene_id: Metbo_2287
symbol: ADZ10501.1
gene_biotype: protein_coding
description:
  PFAM: Dinitrogenase iron-molybdenum cofactor biosynthesis; KEGG: mmg:MTBMA_c01800 FeMo cofactor biosynthesis protein.


ensembl_gene_id: Metbo_2289
symbol: rps3ae
gene_biotype: protein_coding
description:
  KEGG: mmg:MTBMA_c01790 30S ribosomal protein S3Ae; HAMAP: 30S ribosomal protein S3Ae; PFAM: Ribosomal protein S3Ae; Belongs to the eukaryotic ribosomal protein eS1 family.


ensembl_gene_id: Metbo_2290
symbol: ADZ10504.1
gene_biotype: protein_coding
description:
  KEGG: mmg:MTBMA_c01780 hypothetical protein; TIGRFAM: Protein of unknown function DUF92, TMEM19; PFAM: Protein of unknown function DUF92, TMEM19.


ensembl_gene_id: Metbo_2291
symbol: apgM-2
gene_biotype: protein_coding
description:
  Phosphonopyruvate decarboxylase-related protein; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.


ensembl_gene_id: Metbo_2292
symbol: glmM
gene_biotype: protein_coding
description:
  Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.


ensembl_gene_id: Metbo_2293
symbol: ADZ10507.1
gene_biotype: protein_coding
description:
  Glucosamine-1-phosphate N-acetyltransferase; KEGG: mth:MTH1589 glucose-1-phosphate thymidylyltransferase-like protein; PFAM: Nucleotidyl transferase; Bacterial transferase hexapeptide repeat.


ensembl_gene_id: Metbo_2295
symbol: hisC
gene_biotype: protein_coding
description:
  PFAM: Aminotransferase, class I/classII; TIGRFAM: Histidinol-phosphate aminotransferase; HAMAP: Histidinol-phosphate aminotransferase; KEGG: mth:MTH1587 histidinol-phosphate aminotransferase.


ensembl_gene_id: Metbo_2296
symbol: ADZ10510.1
gene_biotype: protein_coding
description:
  KEGG: mfv:Mfer_0127 anaerobic ribonucleoside-triphosphate reductase activating protein; TIGRFAM: Ribonucleoside-triphosphate reductase, anaerobic-like; PFAM: Radical SAM.


ensembl_gene_id: Metbo_2297
symbol: ADZ10511.1
gene_biotype: protein_coding
description:
  PFAM: Tetratricopeptide TPR2; Tetratricopeptide TPR-1; KEGG: mru:mru_0452 TPR repeat-containing protein.


ensembl_gene_id: Metbo_2300
symbol: ADZ10514.1
gene_biotype: protein_coding
description:
  Regulatory protein ArsR; KEGG: rci:LRC567 ArsR family transcriptional regulator; PFAM: HTH transcriptional regulator, ArsR; SMART: HTH transcriptional regulator, ArsR.


ensembl_gene_id: Metbo_2301
symbol: lon
gene_biotype: protein_coding
description:
  Anti-sigma H sporulation factor, LonB; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.


ensembl_gene_id: Metbo_2319
symbol: ADZ10533.1
gene_biotype: protein_coding
description:
  PAS sensor protein; TIGRFAM: PAS; PFAM: PAS fold-3; PAS fold; KEGG: htu:Htur_4080 putative PAS/PAC sensor protein; SMART: PAC motif.


ensembl_gene_id: Metbo_2320
symbol: ADZ10534.1
gene_biotype: protein_coding
description:
  TIGRFAM: PAS; PFAM: Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain; PAS fold-4; PAS fold; ATPase-like, ATP-binding domain; KEGG: cya:CYA_2886 sensory box histidine kinase; SMART: ATPase-like, ATP-binding domain; PAC motif; PAS.


ensembl_gene_id: Metbo_2321
symbol: ADZ10535.1
gene_biotype: protein_coding
description:
  Archaeoflavoprotein AfpA; KEGG: mtp:Mthe_0245 flavoprotein; TIGRFAM: Archaeoflavoprotein AfpA; PFAM: Flavoprotein.


ensembl_gene_id: Metbo_2327
symbol: ADZ10540.1
gene_biotype: protein_coding
description:
  PFAM: Domain of unknown function DUF523; Domain of unknown function DUF1722; KEGG: mac:MA4104 hypothetical protein.


ensembl_gene_id: Metbo_2328
symbol: xerA
gene_biotype: protein_coding
description:
  Tyrosine recombinase xerC; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Belongs to the 'phage' integrase family. XerA subfamily.


ensembl_gene_id: Metbo_2329
symbol: ADZ10542.1
gene_biotype: protein_coding
description:
  ATPase associated with various cellular activities AAA_5; KEGG: mth:MTH892 ATP-dependent protease La related protein; PFAM: ATPase, AAA-5; SMART: ATPase, AAA+ type, core.


ensembl_gene_id: Metbo_2330
symbol: dnaG
gene_biotype: protein_coding
description:
  UPF0095 protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome.


ensembl_gene_id: Metbo_2331
symbol: ADZ10544.1
gene_biotype: protein_coding
description:
  HAMAP: Uncharacterised protein family UPF0292; PFAM: Toprim domain; KEGG: mth:MTH890 hypothetical protein; SMART: Toprim domain.


ensembl_gene_id: Metbo_2333
symbol: ADZ10546.1
gene_biotype: protein_coding
description:
  PFAM: Ribonuclease E inhibitor RraA/Dimethylmenaquinone methyltransferase; KEGG: mfv:Mfer_0465 dimethylmenaquinone methyltransferase.


ensembl_gene_id: Metbo_2339
symbol: prf1
gene_biotype: protein_coding
description:
  Peptide chain release factor subunit 1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.


ensembl_gene_id: Metbo_2340
symbol: ADZ10553.1
gene_biotype: protein_coding
description:
  PyrE-like protein; KEGG: mth:MTH876 orotate phosphoribosyltransferase-like protein; HAMAP: Orotate phosphoribosyltransferase-like; PFAM: Phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.


ensembl_gene_id: Metbo_2341
symbol: ADZ10554.1
gene_biotype: protein_coding
description:
  Oxidoreductase domain protein; PFAM: Oxidoreductase, N-terminal; Oxidoreductase, C-terminal; KEGG: mth:MTH875 3-chlorobenzoate-3,4-dioxygenase dyhydrogenase related protein.


ensembl_gene_id: Metbo_2342
symbol: hemC
gene_biotype: protein_coding
description:
  Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.


ensembl_gene_id: Metbo_2344
symbol: nadK
gene_biotype: protein_coding
description:
  Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.


ensembl_gene_id: Metbo_2345
symbol: ADZ10558.1
gene_biotype: protein_coding
description:
  KEGG: mth:MTH871 bifunctional inositol-1 monophosphatase/fructose-1,6-bisphosphatase; PFAM: Inositol monophosphatase.


ensembl_gene_id: Metbo_2346
symbol: pdaD
gene_biotype: protein_coding
description:
  KEGG: mth:MTH870 hypothetical protein; TIGRFAM: Pyruvoyl-dependent arginine decarboxylase; PFAM: Pyruvoyl-dependent arginine decarboxylase; Belongs to the PdaD family.


ensembl_gene_id: Metbo_2348
symbol: eif5a
gene_biotype: protein_coding
description:
  Translation initiation factor 5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.


ensembl_gene_id: Metbo_2349
symbol: ADZ10562.1
gene_biotype: protein_coding
description:
  Agmatinase; TIGRFAM: Putative agmatinase; KEGG: mth:MTH868 agmatine ureohydrolase; PFAM: Ureohydrolase; Belongs to the arginase family.


ensembl_gene_id: Metbo_2350
symbol: ADZ10563.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein CHP00300; KEGG: mmg:MTBMA_c12620 lysine-oxoglutarate reductase/saccharopine dehydrogenase; TIGRFAM: Conserved hypothetical protein CHP00300; PFAM: LOR/SDH bifunctional enzyme, conserved domain.


ensembl_gene_id: Metbo_2351
symbol: ade
gene_biotype: protein_coding
description:
  Adenine deaminase; PFAM: Amidohydrolase 1; TIGRFAM: Adenine deaminase; HAMAP: Adenine deaminase; KEGG: mmg:MTBMA_c12610 adenine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.


ensembl_gene_id: Metbo_2359
symbol: msrB
gene_biotype: protein_coding
description:
  Peptide methionine sulfoxide reductase msrB; PFAM: Methionine sulphoxide reductase B; TIGRFAM: Methionine sulphoxide reductase B; HAMAP: Methionine sulphoxide reductase B; KEGG: mth:MTH711 methionine sulfoxide reductase B; Belongs to the MsrB Met sulfoxide reductase family.


ensembl_gene_id: Metbo_2364
symbol: cimA
gene_biotype: protein_coding
description:
  Isopropylmalate/citramalate/homocitrate synthase; Catalyzes the condensation of pyruvate and acetyl-coenzyme A to form (R)-citramalate; Belongs to the alpha-IPM synthase/homocitrate synthase family.


ensembl_gene_id: Metbo_2365
symbol: ADZ10578.1
gene_biotype: protein_coding
description:
  TIGRFAM: Conserved hypothetical protein CHP01177; PFAM: Putative RNA methylase; THUMP; KEGG: mfv:Mfer_0515 RNA methylase; SMART: THUMP.


ensembl_gene_id: Metbo_2366
symbol: ADZ10579.1
gene_biotype: protein_coding
description:
  Geranylgeranyl reductase; KEGG: mth:MTH725 hypothetical protein; TIGRFAM: Geranylgeranyl reductase, plant/prokaryotic; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase.


ensembl_gene_id: Metbo_2367
symbol: ADZ10580.1
gene_biotype: protein_coding
description:
  KEGG: mpl:Mpal_0982 protein of unknown function UPF0060; HAMAP: Uncharacterised protein family UPF0060; PFAM: Uncharacterised protein family UPF0060.


ensembl_gene_id: Metbo_2369
symbol: ADZ10582.1
gene_biotype: protein_coding
description:
  UPF0280 protein; KEGG: mth:MTH727 hypothetical protein; HAMAP: Uncharacterised protein family UPF0280; PFAM: Thiamine synthesis ApbE/UPF0280; Belongs to the UPF0280 family.


ensembl_gene_id: Metbo_2370
symbol: ADZ10583.1
gene_biotype: protein_coding
description:
  TIGRFAM: Molybdenum cofactor synthesis; PFAM: MoeA, N-terminal and linker domain; Molybdopterin binding; MoeA, C-terminal, domain IV; KEGG: mfv:Mfer_0296 molybdenum cofactor synthesis domain protein; SMART: Molybdopterin binding.


ensembl_gene_id: Metbo_2371
symbol: eif1a
gene_biotype: protein_coding
description:
  Translation initiation factor 1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.


ensembl_gene_id: Metbo_2373
symbol: ADZ10586.1
gene_biotype: protein_coding
description:
  KH domain protein; KEGG: mth:MTH1006 putative RNA-processing protein; TIGRFAM: KH domain protein, archaea; SMART: K Homology.


ensembl_gene_id: Metbo_2374
symbol: top6B
gene_biotype: protein_coding
description:
  DNA topoisomerase VI, B subunit; Relaxes both positive and negative superturns and exhibits a strong decatenase activity.


ensembl_gene_id: Metbo_2375
symbol: top6A
gene_biotype: protein_coding
description:
  Type 2 DNA topoisomerase 6 subunit A; Relaxes both positive and negative superturns and exhibits a strong decatenase activity; Belongs to the TOP6A family.


ensembl_gene_id: Metbo_2377
symbol: ADZ10590.1
gene_biotype: protein_coding
description:
  Polyketide cyclase/dehydrase; KEGG: kfl:Kfla_1149 hypothetical protein; manually curated; PFAM: Polyketide cyclase/dehydrase.


ensembl_gene_id: Metbo_2379
symbol: gap-2
gene_biotype: protein_coding
description:
  KEGG: mmg:MTBMA_c13910 glyceraldehyde 3-phosphate dehydrogenase; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; TIGRFAM: Glyceraldehyde-3-phosphate dehydrogenase, type II; HAMAP: Glyceraldehyde-3-phosphate dehydrogenase; SMART: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain.


ensembl_gene_id: Metbo_2381
symbol: ADZ10594.1
gene_biotype: protein_coding
description:
  PHP domain protein; KEGG: mba:Mbar_A1414 hypothetical protein; PFAM: PHP, C-terminal; SMART: Polymerase/histidinol phosphatase, N-terminal.


ensembl_gene_id: Metbo_2382
symbol: ADZ10595.1
gene_biotype: protein_coding
description:
  O-phospho-L-seryl-tRNA:Cys-tRNA synthase; Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L- cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)); Belongs to the SepCysS family.


ensembl_gene_id: Metbo_2383
symbol: ADZ10596.1
gene_biotype: protein_coding
description:
  KEGG: mth:MTH628 hypothetical protein; PFAM: Bacterial transcription activator, effector binding; SMART: Bacterial transcription activator, effector binding.


ensembl_gene_id: Metbo_2385
symbol: ADZ10598.1
gene_biotype: protein_coding
description:
  PFAM: DNA ligase, ATP-dependent, central; DNA ligase, ATP-dependent, C-terminal; KEGG: afu:AF1725 DNA ligase, putative.


ensembl_gene_id: Metbo_2386
symbol: ADZ10599.1
gene_biotype: protein_coding
description:
  Ku domain protein; KEGG: mpd:MCP_0581 hypothetical protein; PFAM: DNA helicase, ATP-dependent, Ku type; SMART: DNA helicase, ATP-dependent, Ku type.


ensembl_gene_id: Metbo_2388
symbol: rps10
gene_biotype: protein_coding
description:
  30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.


ensembl_gene_id: Metbo_2389
symbol: tuf
gene_biotype: protein_coding
description:
  Translation elongation factor EF-1, subunit alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.


ensembl_gene_id: Metbo_2390
symbol: fusA
gene_biotype: protein_coding
description:
  Translation elongation factor aEF-2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF [...]


ensembl_gene_id: Metbo_2391
symbol: rps7
gene_biotype: protein_coding
description:
  Ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family.


ensembl_gene_id: Metbo_2392
symbol: rps12
gene_biotype: protein_coding
description:
  Ribosomal protein S23 (S12); With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family.


ensembl_gene_id: Metbo_2393
symbol: nusA
gene_biotype: protein_coding
description:
  NusA family KH domain protein; Participates in transcription termination. Belongs to the NusA family.


ensembl_gene_id: Metbo_2394
symbol: rpl30e
gene_biotype: protein_coding
description:
  KEGG: mmg:MTBMA_c14400 50S ribosomal protein L30e; HAMAP: Ribosomal protein L30e; PFAM: Ribosomal protein L7Ae/L30e/S12e/Gadd45; Belongs to the eukaryotic ribosomal protein eL30 family.


ensembl_gene_id: Metbo_2395
symbol: rpoA2
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: Metbo_2397
symbol: ADZ10610.1
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: Metbo_2398
symbol: ADZ10611.1
gene_biotype: protein_coding
description:
  PFAM: RNA polymerase, beta subunit, protrusion; RNA polymerase Rpb2, domain 2; RNA polymerase Rpb2, domain 3; KEGG: mst:Msp_1375 DNA-directed RNA polymerase subunit beta''; Belongs to the RNA polymerase beta chain family.


ensembl_gene_id: Metbo_2399
symbol: rpoH
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase subunit H; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family.


ensembl_gene_id: Metbo_2400
symbol: pgk
gene_biotype: protein_coding
description:
  HAMAP: Phosphoglycerate kinase; KEGG: mth:MTH1042 phosphoglycerate kinase; PFAM: Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.


ensembl_gene_id: Metbo_2401
symbol: tpiA
gene_biotype: protein_coding
description:
  Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.


ensembl_gene_id: Metbo_2402
symbol: taw1
gene_biotype: protein_coding
description:
  Wyosine base formation domain-containing protein; Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe).


ensembl_gene_id: Metbo_2405
symbol: sucC
gene_biotype: protein_coding
description:
  Succinyl-CoA ligase (ADP-forming) subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.


ensembl_gene_id: Metbo_2406
symbol: ADZ10619.1
gene_biotype: protein_coding
description:
  KEGG: mru:mru_1826 2-oxoglutarate ferredoxin oxidoreductase subunit gamma KorC; PFAM: Pyruvate/ketoisovalerate oxidoreductase, catalytic domain.


ensembl_gene_id: Metbo_2407
symbol: ADZ10620.1
gene_biotype: protein_coding
description:
  KEGG: mth:MTH1034 2-oxoglutarate ferredoxin oxidoreductase subunit beta; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding.


ensembl_gene_id: Metbo_2408
symbol: ADZ10621.1
gene_biotype: protein_coding
description:
  KEGG: mmg:MTBMA_c14150 2-oxoglutarate synthase, subunit alpha; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Transketolase, C-terminal.


ensembl_gene_id: Metbo_2409
symbol: ADZ10622.1
gene_biotype: protein_coding
description:
  PFAM: 4Fe-4S binding domain; KEGG: mfv:Mfer_0036 2-oxoglutarate ferredoxin oxidoreductase, delta subunit.


ensembl_gene_id: Metbo_2410
symbol: ADZ10623.1
gene_biotype: protein_coding
description:
  PFAM: 4Fe-4S binding domain; KEGG: mvn:Mevan_0640 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein.


ensembl_gene_id: Metbo_2411
symbol: ADZ10624.1
gene_biotype: protein_coding
description:
  PFAM: Dinitrogenase iron-molybdenum cofactor biosynthesis; KEGG: mmx:MmarC6_1796 dinitrogenase iron-molybdenum cofactor biosynthesis protein.


ensembl_gene_id: Metbo_2412
symbol: ADZ10625.1
gene_biotype: protein_coding
description:
  Nitrogenase; KEGG: mmp:MMP0859 nitrogenase; PFAM: Nitrogenase/oxidoreductase, component 1; Belongs to the NifD/NifK/NifE/NifN family.


ensembl_gene_id: Metbo_2413
symbol: ADZ10626.1
gene_biotype: protein_coding
description:
  KEGG: mvn:Mevan_0060 nitrogenase MoFe cofactor biosynthesis protein NifE; TIGRFAM: Nitrogenase MoFe cofactor biosynthesis protein NifE; PFAM: Nitrogenase/oxidoreductase, component 1; Belongs to the NifD/NifK/NifE/NifN family.


ensembl_gene_id: Metbo_2414
symbol: ADZ10627.1
gene_biotype: protein_coding
description:
  Nitrogenase; KEGG: mvn:Mevan_0061 nitrogenase; PFAM: Nitrogenase/oxidoreductase, component 1; Belongs to the NifD/NifK/NifE/NifN family.


ensembl_gene_id: Metbo_2415
symbol: ADZ10628.1
gene_biotype: protein_coding
description:
  Nitrogenase alpha chain; KEGG: mmg:MTBMA_c01490 nitrogenase molybdenum-iron protein, alpha chain; TIGRFAM: Nitrogenase alpha chain; Nitrogenase component 1, alpha chain; PFAM: Nitrogenase/oxidoreductase, component 1.


ensembl_gene_id: Metbo_2416
symbol: ADZ10629.1
gene_biotype: protein_coding
description:
  KEGG: mmz:MmarC7_0100 nitrogen regulatory protein P-II; PFAM: Nitrogen regulatory protein PII; SMART: Nitrogen regulatory protein PII; Belongs to the P(II) protein family.


ensembl_gene_id: Metbo_2417
symbol: ADZ10630.1
gene_biotype: protein_coding
description:
  KEGG: mmq:MmarC5_0659 nitrogen regulatory protein P-II; PFAM: Nitrogen regulatory protein PII; SMART: Nitrogen regulatory protein PII; Belongs to the P(II) protein family.


ensembl_gene_id: Metbo_2420
symbol: ADZ10633.1
gene_biotype: protein_coding
description:
  1-(5-phosphoribosyl)-5-amino-4-imidazole- carboxylate (AIR) carboxylase; PFAM: Phosphoribosylaminoimidazole carboxylase, core; Protein of unknown function DUF2089; KEGG: msi:Msm_1105 NCAIR mutase related protein, PurE.


ensembl_gene_id: Metbo_2423
symbol: mptD
gene_biotype: protein_coding
description:
  Protein of unknown function DUF372; Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD); Belongs to the archaeal dihydroneopterin aldolase family.


ensembl_gene_id: Metbo_2424
symbol: ADZ10637.1
gene_biotype: protein_coding
description:
  Sortase family protein; KEGG: mth:MTH1030 hypothetical protein; TIGRFAM: Peptidase C60, sortase A/B; PFAM: Peptidase C60, sortase A/B.


ensembl_gene_id: Metbo_2427
symbol: ADZ10640.1
gene_biotype: protein_coding
description:
  KEGG: mth:MTH1027 CDP-diacylglycerol-serine O-phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--serine O-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase.


ensembl_gene_id: Metbo_2428
symbol: asd-2
gene_biotype: protein_coding
description:
  Phosphatidylserine decarboxylase proenzyme; Catalyzes the formation of archaetidylethanolamine (PtdEtn) from archaetidylserine (PtdSer); Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.


ensembl_gene_id: Metbo_2430
symbol: ADZ10643.1
gene_biotype: protein_coding
description:
  PFAM: Cell shape determining protein MreB/Mrl; KEGG: mth:MTH1024 rod shape-determining protein MreB.


ensembl_gene_id: Metbo_2431
symbol: rnhB
gene_biotype: protein_coding
description:
  Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.


ensembl_gene_id: Metbo_2434
symbol: purO
gene_biotype: protein_coding
description:
  IMP cyclohydrolase; Catalyzes the cyclization of 5-formylamidoimidazole-4- carboxamide ribonucleotide to IMP.


ensembl_gene_id: Metbo_2435
symbol: cofE
gene_biotype: protein_coding
description:
  F420-0:gamma-glutamyl ligase; Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8- didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420- 0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives.


ensembl_gene_id: Metbo_2436
symbol: cofD
gene_biotype: protein_coding
description:
  LPPG:FO 2-phospho-L-lactate transferase; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP.


ensembl_gene_id: Metbo_2437
symbol: gch3
gene_biotype: protein_coding
description:
  GTP cyclohydrolase III; Catalyzes the formation of 2-amino-5-formylamino-6- ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity; Belongs to the archaeal-type GTP cyclohydrolase family.


ensembl_gene_id: Metbo_2438
symbol: ADZ10651.1
gene_biotype: protein_coding
description:
  TIM-barrel protein; TIGRFAM: tRNA-dihydrouridine synthase, TIM-barrel, NifR3-related; KEGG: mfv:Mfer_0317 tim-barrel protein.


ensembl_gene_id: Metbo_2439
symbol: ADZ10652.1
gene_biotype: protein_coding
description:
  SMART: ATPase, AAA+ type, core; TIGRFAM: Methyl coenzyme M reductase system, component A2; KEGG: mmg:MTBMA_c13970 methyl-coenzyme M reductase, component A2; PFAM: ABC transporter-like.


ensembl_gene_id: Metbo_2441
symbol: ADZ10654.1
gene_biotype: protein_coding
description:
  TIGRFAM: Sirohaem synthase, N-terminal; KEGG: msi:Msm_0968 bifunctional precorrin-2 oxidase/chelatase (siroheme synthase), CysG.


ensembl_gene_id: Metbo_2442
symbol: hemA
gene_biotype: protein_coding
description:
  Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).


ensembl_gene_id: Metbo_2444
symbol: ADZ10657.1
gene_biotype: protein_coding
description:
  AAA ATPase central domain protein; KEGG: mth:MTH1011 ATP-dependent 26S protease regulatory subunit 8; PFAM: ATPase, AAA-type, core; SMART: ATPase, AAA+ type, core.


ensembl_gene_id: Metbo_2445
symbol: ADZ10658.1
gene_biotype: protein_coding
description:
  KEGG: msi:Msm_0963 endonuclease IV; PFAM: Xylose isomerase, TIM barrel domain; SMART: Endodeoxyribonuclease IV.


ensembl_gene_id: Metbo_2446
symbol: ADZ10659.1
gene_biotype: protein_coding
description:
  KEGG: mmg:MTBMA_c10960 thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase.


ensembl_gene_id: Metbo_2447
symbol: gatE
gene_biotype: protein_coding
description:
  Glutamyl-tRNA(Gln) amidotransferase subunit E; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.


ensembl_gene_id: Metbo_2448
symbol: gatD
gene_biotype: protein_coding
description:
  Glutamyl-tRNA(Gln) amidotransferase subunit D; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.


ensembl_gene_id: Metbo_2449
symbol: ADZ10662.1
gene_biotype: protein_coding
description:
  TIGRFAM: Exodeoxyribonuclease III xth; AP endonuclease, family 1; KEGG: mmg:MTBMA_c06610 DNA lyase; PFAM: Endonuclease/exonuclease/phosphatase.


ensembl_gene_id: Metbo_2450
symbol: ADZ10663.1
gene_biotype: protein_coding
description:
  TIGRFAM: 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate; KEGG: mmg:MTBMA_c09240 pyruvate flavodoxin/ferredoxin oxidoreductase, subunit beta; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding.


ensembl_gene_id: Metbo_2451
symbol: ADZ10664.1
gene_biotype: protein_coding
description:
  TIGRFAM: 2-oxoacid:acceptor oxidoreductase, alpha subunit; KEGG: mmg:MTBMA_c09230 pyruvate flavodoxin/ferredoxin oxidoreductase, subunit alpha; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain.


ensembl_gene_id: Metbo_2452
symbol: ADZ10665.1
gene_biotype: protein_coding
description:
  PFAM: Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; KEGG: mmp:MMP1271 2-oxoisovalerate oxidoreductase subunit alpha.


ensembl_gene_id: Metbo_2453
symbol: ADZ10666.1
gene_biotype: protein_coding
description:
  3-methyl-2-oxobutanoate dehydrogenase (ferredoxin); KEGG: mmp:MMP1272 2-ketoisovalerate ferredoxin reductase; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal.


ensembl_gene_id: Metbo_2454
symbol: ADZ10667.1
gene_biotype: protein_coding
description:
  PFAM: 4Fe-4S binding domain; KEGG: mmq:MmarC5_0318 ketoisovalerate ferredoxin oxidoreductase, delta subunit.


ensembl_gene_id: Metbo_2455
symbol: ADZ10668.1
gene_biotype: protein_coding
description:
  Butyrate--CoA ligase; KEGG: mba:Mbar_A2172 AMP-binding protein; PFAM: AMP-dependent synthetase/ligase.


ensembl_gene_id: Metbo_2456
symbol: ADZ10669.1
gene_biotype: protein_coding
description:
  KEGG: mmz:MmarC7_0521 cupin 2 domain-containing protein; PFAM: Cupin 2, conserved barrel; Helix-turn-helix type 3; SMART: Helix-turn-helix type 3.


ensembl_gene_id: Metbo_2457
symbol: ADZ10670.1
gene_biotype: protein_coding
description:
  Protein of unknown function DUF355; PFAM: Adenosine specific kinase; KEGG: mmg:MTBMA_c10870 hypothetical protein.


ensembl_gene_id: Metbo_2459
symbol: ADZ10672.1
gene_biotype: protein_coding
description:
  Manually curated; TIGRFAM: Archaeoflavoprotein AfpA; KEGG: mtp:Mthe_0245 flavoprotein; PFAM: Flavoprotein.


ensembl_gene_id: Metbo_2461
symbol: ADZ10674.1
gene_biotype: protein_coding
description:
  KEGG: mmg:MTBMA_c01700 phosphomannomutase; PFAM: Alpha-D-phosphohexomutase, alpha/beta/alpha domain I; Alpha-D-phosphohexomutase, alpha/beta/alpha domain II; Alpha-D-phosphohexomutase, alpha/beta/alpha domain III; Alpha-D-phosphohexomutase, C-terminal; Belongs to the phosphohexose mutase family.


ensembl_gene_id: Metbo_2462
symbol: ADZ10675.1
gene_biotype: protein_coding
description:
  PFAM: Nucleic acid binding, OB-fold, tRNA/helicase-type; KEGG: mru:mru_0446 OB fold nucleic acid binding domain-containing protein.


ensembl_gene_id: Metbo_2463
symbol: lig
gene_biotype: protein_coding
description:
  DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.


ensembl_gene_id: Metbo_2467
symbol: thiC
gene_biotype: protein_coding
description:
  Phosphomethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.


ensembl_gene_id: Metbo_2468
symbol: ADZ10681.1
gene_biotype: protein_coding
description:
  CBS domain containing membrane protein; KEGG: mth:MTH1575 inosine-5'-monophosphate dehydrogenase related protein X; PFAM: Cystathionine beta-synthase, core; SMART: Cystathionine beta-synthase, core.


ensembl_gene_id: Metbo_2469
symbol: ADZ10682.1
gene_biotype: protein_coding
description:
  Methanogenesis marker protein 8; KEGG: rci:LRC199 hypothetical protein; TIGRFAM: Uncharacterised conserved protein UCP004929, methanogenesis; PFAM: Uncharacterised conserved protein UCP004929, methanogenesis.


ensembl_gene_id: Metbo_2473
symbol: ADZ10686.1
gene_biotype: protein_coding
description:
  Conserved repeat domain protein; TIGRFAM: Domain of unknown function DUF11; KEGG: dmo:Dmoj_GI17948 GI17948 gene product from transcript GI17948-RA.


ensembl_gene_id: Metbo_2474
symbol: ADZ10687.1
gene_biotype: protein_coding
description:
  PKD domain containing protein; KEGG: mpl:Mpal_1810 carbohydrate binding family 6; PFAM: PKD domain; SMART: PKD/Chitinase domain.


ensembl_gene_id: Metbo_2479
symbol: ADZ10692.1
gene_biotype: protein_coding
description:
  PFAM: 4Fe-4S binding domain; KEGG: mpd:MCP_1991 putative CoB--CoM heterodisulfide reductase iron-sulfur subunit C.


ensembl_gene_id: Metbo_2480
symbol: ADZ10693.1
gene_biotype: protein_coding
description:
  ABC-type transporter, periplasmic subunit; PFAM: Periplasmic binding protein; KEGG: mru:mru_0251 ABC transporter substrate-binding protein.


ensembl_gene_id: Metbo_2483
symbol: ADZ10696.1
gene_biotype: protein_coding
description:
  PFAM: UBA/THIF-type NAD/FAD binding fold; KEGG: mmg:MTBMA_c01580 molybdopterin biosynthesis protein MoeB.


ensembl_gene_id: Metbo_2484
symbol: ADZ10697.1
gene_biotype: protein_coding
description:
  TIGRFAM: Glutamine synthetase type I; KEGG: mth:MTH1570 glutamine synthetase; PFAM: Glutamine synthetase, catalytic domain; Glutamine synthetase, beta-Grasp.


ensembl_gene_id: Metbo_2485
symbol: ADZ10698.1
gene_biotype: protein_coding
description:
  PFAM: Domain of unknown function DUF128; Ribonuclease R winged-helix domain; KEGG: mmg:MTBMA_c01560 transcriptional repressor of nif & GlnA operons NrpR.


ensembl_gene_id: Metbo_2486
symbol: ADZ10699.1
gene_biotype: protein_coding
description:
  Uncharacterized protein family UPF0066; KEGG: mru:mru_2214 hypothetical protein; TIGRFAM: Uncharacterised protein family UPF0066; PFAM: Uncharacterised protein family UPF0066.


ensembl_gene_id: Metbo_2487
symbol: ADZ10700.1
gene_biotype: protein_coding
description:
  PFAM: Formylmethanofuran dehydrogenase, subunit E domain; KEGG: msi:Msm_1396 tungsten formylmethanofuran dehydrogenase, subunit E, FwdE.


ensembl_gene_id: Metbo_2488
symbol: ADZ10701.1
gene_biotype: protein_coding
description:
  Iron-chelate-transporting ATPase; PFAM: ABC transporter-like; KEGG: msi:Msm_1395 iron(III) ABC transporter, ATPase component; SMART: ATPase, AAA+ type, core.


ensembl_gene_id: Metbo_2489
symbol: ADZ10702.1
gene_biotype: protein_coding
description:
  ABC-type transporter, integral membrane subunit; PFAM: ABC transporter permease protein; KEGG: msi:Msm_1394 iron(III) ABC transporter, permease component.


ensembl_gene_id: Metbo_2496
symbol: ADZ10709.1
gene_biotype: protein_coding
description:
  TIGRFAM: Parallel beta-helix repeat-2; Domain of unknown function DUF11; KEGG: mru:mru_0255 adhesin-like protein.


ensembl_gene_id: Metbo_2497
symbol: ADZ10710.1
gene_biotype: protein_coding
description:
  Conserved repeat domain protein; TIGRFAM: Domain of unknown function DUF11; KEGG: msi:Msm_1398 adhesin-like protein.


ensembl_gene_id: Metbo_2500
symbol: ADZ10713.1
gene_biotype: protein_coding
description:
  KEGG: msi:Msm_0131 molybdenum-binding protein, MopI; TIGRFAM: Molybdenum-pterin binding; PFAM: Transport-associated OB, type 1.


ensembl_gene_id: Metbo_2502
symbol: ADZ10715.1
gene_biotype: protein_coding
description:
  4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; PFAM: 4Fe-4S binding domain; KEGG: msi:Msm_0783 tungsten formylmethanofuran dehydrogenase, subunit F, FwdF.


ensembl_gene_id: Metbo_2503
symbol: ADZ10716.1
gene_biotype: protein_coding
description:
  Putative transcriptional regulator, ModE family; PFAM: Transport-associated OB, type 1; HTH transcriptional regulator, LysR; KEGG: msi:Msm_1207 molybdate transport system regulatory protein.


ensembl_gene_id: Metbo_2504
symbol: ADZ10717.1
gene_biotype: protein_coding
description:
  PFAM: Bacterial extracellular solute-binding, family 1; KEGG: mfv:Mfer_0984 extracellular solute-binding protein family 1.


ensembl_gene_id: Metbo_2505
symbol: ADZ10718.1
gene_biotype: protein_coding
description:
  PFAM: Formylmethanofuran dehydrogenase, subunit E domain; KEGG: mbu:Mbur_0286 formylmethanofuran dehydrogenase, subunit E.


ensembl_gene_id: Metbo_2508
symbol: ADZ10721.1
gene_biotype: protein_coding
description:
  TIGRFAM: Formylmethanofuran dehydrogenase subunit C; KEGG: mru:mru_0345 tungsten formylmethanofuran dehydrogenase subunit C FwdC; PFAM: Glutamate synthase, alpha subunit, C-terminal.


ensembl_gene_id: Metbo_2509
symbol: ADZ10722.1
gene_biotype: protein_coding
description:
  KEGG: mru:mru_0344 tungsten formylmethanofuran dehydrogenase subunit A FwdA; TIGRFAM: Formylmethanofuran dehydrogenase, subunit A; PFAM: Amidohydrolase 3.


ensembl_gene_id: Metbo_2510
symbol: ADZ10723.1
gene_biotype: protein_coding
description:
  TIGRFAM: Formylmethanofuran dehydrogenase, subunit B; KEGG: msi:Msm_1412 tungsten formylmethanofuran dehydrogenase, subunit B, FwdB; PFAM: Molybdopterin oxidoreductase.


ensembl_gene_id: Metbo_2511
symbol: ADZ10724.1
gene_biotype: protein_coding
description:
  Molybdopterin dinucleotide-binding region; PFAM: Molydopterin dinucleotide-binding domain; KEGG: msi:Msm_1411 tungsten formylmethanofuran dehydrogenase, subunit D, FwdD.


ensembl_gene_id: Metbo_2512
symbol: ADZ10725.1
gene_biotype: protein_coding
description:
  4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; PFAM: 4Fe-4S binding domain; KEGG: mru:mru_0341 tungsten formylmethanofuran dehydrogenase subunit G FwdG.


ensembl_gene_id: Metbo_2513
symbol: ADZ10726.1
gene_biotype: protein_coding
description:
  4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; PFAM: 4Fe-4S binding domain; KEGG: mru:mru_0340 tungsten formylmethanofuran dehydrogenase subunit F FwdF.


ensembl_gene_id: Metbo_2514
symbol: ADZ10727.1
gene_biotype: protein_coding
description:
  PFAM: Helix-turn-helix type 3; 4Fe-4S binding domain; KEGG: mth:MTH1553 tungsten formylmethanofuran dehydrogenase, subunit H.


ensembl_gene_id: Metbo_2515
symbol: ADZ10728.1
gene_biotype: protein_coding
description:
  TIGRFAM: Formate dehydrogenase, alpha subunit; PFAM: Molybdopterin oxidoreductase; Molybdopterin oxidoreductase, Fe4S4 domain; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; Ferredoxin; 4Fe-4S binding domain; Molydopterin dinucleotide-binding domain; KEGG: mth:MTH1552 formate dehydrogenase, alpha subunit-like protein; SMART: Molybdopterin oxidoreductase, Fe4S4 domain; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding.


ensembl_gene_id: Metbo_2516
symbol: ADZ10729.1
gene_biotype: protein_coding
description:
  KEGG: tpd:Teth39_0854 putative molybdopterin-guanine dinucleotide biosynthesis protein MobB/FeS domain-containing protein protein; TIGRFAM: Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB), conserved domain; PFAM: Putative Fe-S cluster.


ensembl_gene_id: Metbo_2517
symbol: moaA
gene_biotype: protein_coding
description:
  Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family.


ensembl_gene_id: Metbo_2518
symbol: ADZ10731.1
gene_biotype: protein_coding
description:
  NADH dehydrogenase (quinone); PFAM: NADH:ubiquinone oxidoreductase, 51kDa subunit; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; 4Fe-4S binding domain; KEGG: mth:MTH1549 NADP-reducing hydrogenase, subunit C; SMART: NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding.


ensembl_gene_id: Metbo_2519
symbol: ADZ10732.1
gene_biotype: protein_coding
description:
  PFAM: NADH:ubiquinone oxidoreductase, 24kDa subunit; KEGG: mth:MTH1548 NADH dehydrogenase subunit E.


ensembl_gene_id: Metbo_2520
symbol: ADZ10733.1
gene_biotype: protein_coding
description:
  PFAM: Carboxymuconolactone decarboxylase; KEGG: tbd:Tbd_0657 carboxymuconolactone decarboxylase domain-containing protein.


ensembl_gene_id: Metbo_2521
symbol: fdhD
gene_biotype: protein_coding
description:
  Protein fdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.


ensembl_gene_id: Metbo_2522
symbol: ADZ10735.1
gene_biotype: protein_coding
description:
  TIGRFAM: 6-phospho 3-hexuloisomerase; KEGG: mfv:Mfer_1158 3-hexulose-6-phosphate isomerase; PFAM: Sugar isomerase (SIS).


ensembl_gene_id: Metbo_2523
symbol: ADZ10736.1
gene_biotype: protein_coding
description:
  PFAM: HTH transcriptional regulator, LysR; KEGG: mru:mru_0249 transcriptional regulator LysR family.


ensembl_gene_id: Metbo_2524
symbol: ADZ10737.1
gene_biotype: protein_coding
description:
  PfkB domain protein; PFAM: Carbohydrate/purine kinase; KEGG: mth:MTH1544 ribokinase; Belongs to the carbohydrate kinase PfkB family.


ensembl_gene_id: Metbo_2525
symbol: ADZ10738.1
gene_biotype: protein_coding
description:
  Phosphomethylpyrimidine synthase; TIGRFAM: Thiamine biosynthesis protein ThiC; HAMAP: Thiamine biosynthesis protein ThiC; KEGG: mth:MTH1543 thiamine biosynthesis protein ThiC; PFAM: Thiamine biosynthesis protein ThiC.


ensembl_gene_id: Metbo_2526
symbol: lysS
gene_biotype: protein_coding
description:
  PFAM: Lysyl-tRNA synthetase, class Ic; TIGRFAM: Lysyl-tRNA synthetase, class I; HAMAP: Lysyl-tRNA synthetase, class I, archaeal-type; KEGG: mth:MTH1542 hypothetical protein; Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: Metbo_2529
symbol: ADZ10742.1
gene_biotype: protein_coding
description:
  Amidohydrolase; TIGRFAM: Peptidase M20D, amidohydrolase; KEGG: gfo:GFO_2325 M20 family peptidase; PFAM: Peptidase M20; Peptidase M20, dimerisation.


ensembl_gene_id: Metbo_2531
symbol: ADZ10744.1
gene_biotype: protein_coding
description:
  TIGRFAM: Ribonucleoside-triphosphate reductase, anaerobic; KEGG: mmg:MTBMA_c01230 anaerobic ribonucleotide-triphosphate reductase; PFAM: ATP-cone.


ensembl_gene_id: Metbo_2532
symbol: polC
gene_biotype: protein_coding
description:
  DNA polymerase II large subunit; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase.


ensembl_gene_id: Metbo_2533
symbol: secG
gene_biotype: protein_coding
description:
  Preprotein translocase subunit secG; Involved in protein export. The function of the beta subunit is unknown, but it may be involved in stabilization of the trimeric complex.


