# geneInfo

ensembl_gene_id: DespoDRAFT_00023
symbol: EIM62079.1
gene_biotype: protein_coding
description:
  PFAM: Phage derived protein Gp49-like (DUF891); TIGRFAM: putative addiction module killer protein; manually curated.


ensembl_gene_id: DespoDRAFT_00028
symbol: EIM62081.1
gene_biotype: protein_coding
description:
  Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains; PFAM: GAF domain; Bacterial regulatory protein, Fis family; Sigma-54 interaction domain; TIGRFAM: Nif-specific regulatory protein.


ensembl_gene_id: DespoDRAFT_00034
symbol: EIM62087.1
gene_biotype: protein_coding
description:
  Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.


ensembl_gene_id: DespoDRAFT_00035
symbol: EIM62088.1
gene_biotype: protein_coding
description:
  PFAM: PEP-utilising enzyme, mobile domain; Pyruvate phosphate dikinase, PEP/pyruvate binding domain.


ensembl_gene_id: DespoDRAFT_00040
symbol: EIM62093.1
gene_biotype: protein_coding
description:
  Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains; PFAM: Response regulator receiver domain.


ensembl_gene_id: DespoDRAFT_00042
symbol: EIM62095.1
gene_biotype: protein_coding
description:
  PFAM: Pterin binding enzyme; B12 binding domain; Homocysteine S-methyltransferase; TIGRFAM: 5-methyltetrahydrofolate--homocysteine methyltransferase; methylmalonyl-CoA mutase C-terminal domain.


ensembl_gene_id: DespoDRAFT_00044
symbol: EIM62097.1
gene_biotype: protein_coding
description:
  PFAM: HAMP domain; Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; Hpt domain.


ensembl_gene_id: DespoDRAFT_00045
symbol: EIM62098.1
gene_biotype: protein_coding
description:
  PFAM: EAL domain; Response regulator receiver domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.


ensembl_gene_id: DespoDRAFT_00049
symbol: EIM62101.1
gene_biotype: protein_coding
description:
  PFAM: Starch synthase catalytic domain; Glycosyl transferases group 1; TIGRFAM: glycogen/starch synthases, ADP-glucose type.


ensembl_gene_id: DespoDRAFT_00057
symbol: EIM62106.1
gene_biotype: protein_coding
description:
  P-type ATPase, translocating; PFAM: E1-E2 ATPase; Cation transporting ATPase, C-terminus; haloacid dehalogenase-like hydrolase; Cation transporter/ATPase, N-terminus; TIGRFAM: plasma-membrane calcium-translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC.


ensembl_gene_id: DespoDRAFT_00060
symbol: prfB
gene_biotype: protein_coding
description:
  Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.


ensembl_gene_id: DespoDRAFT_00061
symbol: lnt
gene_biotype: protein_coding
description:
  Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily.


ensembl_gene_id: DespoDRAFT_00063
symbol: EIM62112.1
gene_biotype: protein_coding
description:
  Molecular chaperone (small heat shock protein); PFAM: Hsp20/alpha crystallin family; Belongs to the small heat shock protein (HSP20) family.


ensembl_gene_id: DespoDRAFT_00064
symbol: lon
gene_biotype: protein_coding
description:
  ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.


ensembl_gene_id: DespoDRAFT_00065
symbol: rlpA
gene_biotype: protein_coding
description:
  Rare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.


ensembl_gene_id: DespoDRAFT_00066
symbol: EIM62115.1
gene_biotype: protein_coding
description:
  PFAM: Polynucleotide kinase 3 phosphatase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E; D,D-heptose 1,7-bisphosphate phosphatase; HAD-superfamily hydrolase, subfamily IIIA; histidinol-phosphate phosphatase family domain.


ensembl_gene_id: DespoDRAFT_00067
symbol: recD2
gene_biotype: protein_coding
description:
  Helicase, putative, RecD/TraA family; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily.


ensembl_gene_id: DespoDRAFT_00070
symbol: rho
gene_biotype: protein_coding
description:
  Transcription termination factor; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.


ensembl_gene_id: DespoDRAFT_00072
symbol: clpX
gene_biotype: protein_coding
description:
  Endopeptidase Clp ATP-binding regulatory subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.


ensembl_gene_id: DespoDRAFT_00073
symbol: clpP
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.


ensembl_gene_id: DespoDRAFT_00074
symbol: tig
gene_biotype: protein_coding
description:
  Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.


ensembl_gene_id: DespoDRAFT_00100
symbol: EIM62146.1
gene_biotype: protein_coding
description:
  Phosphate ABC transporter, phosphate-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import; Belongs to the PstS family.


ensembl_gene_id: DespoDRAFT_00101
symbol: EIM62147.1
gene_biotype: protein_coding
description:
  Phosphate ABC transporter, permease protein PstC; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: DespoDRAFT_00102
symbol: EIM62148.1
gene_biotype: protein_coding
description:
  Phosphate ABC transporter, permease protein PstA; PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: phosphate ABC transporter, permease protein PstA.


ensembl_gene_id: DespoDRAFT_00103
symbol: pstB
gene_biotype: protein_coding
description:
  Phosphate ABC transporter, ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.


ensembl_gene_id: DespoDRAFT_00104
symbol: EIM62150.1
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.


ensembl_gene_id: DespoDRAFT_00108
symbol: EIM62154.1
gene_biotype: protein_coding
description:
  2-oxoacid:ferredoxin oxidoreductase, beta subunit; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain.


ensembl_gene_id: DespoDRAFT_00109
symbol: EIM62155.1
gene_biotype: protein_coding
description:
  PFAM: Pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family.


ensembl_gene_id: DespoDRAFT_00110
symbol: EIM62156.1
gene_biotype: protein_coding
description:
  PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, middle domain; Acyl-CoA dehydrogenase, N-terminal domain.


ensembl_gene_id: DespoDRAFT_00118
symbol: EIM62164.1
gene_biotype: protein_coding
description:
  Membrane-bound serine protease (ClpP class); PFAM: NfeD-like; overlaps another CDS with the same product name.


ensembl_gene_id: DespoDRAFT_00119
symbol: EIM62165.1
gene_biotype: protein_coding
description:
  Membrane-bound serine protease (ClpP class); PFAM: Serine dehydrogenase proteinase; NfeD-like; overlaps another CDS with the same product name.


ensembl_gene_id: DespoDRAFT_00120
symbol: EIM62166.1
gene_biotype: protein_coding
description:
  Mn-dependent transcriptional regulator; PFAM: Iron dependent repressor, metal binding and dimerisation domain; Iron dependent repressor, N-terminal DNA binding domain.


ensembl_gene_id: DespoDRAFT_00121
symbol: EIM62167.1
gene_biotype: protein_coding
description:
  Putative DNA-binding protein; PFAM: Protein of unknown function DUF134; Belongs to the UPF0251 family.


ensembl_gene_id: DespoDRAFT_00122
symbol: hisD
gene_biotype: protein_coding
description:
  Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.


ensembl_gene_id: DespoDRAFT_00126
symbol: atpD
gene_biotype: protein_coding
description:
  ATP synthase, F1 beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.


ensembl_gene_id: DespoDRAFT_00127
symbol: atpC
gene_biotype: protein_coding
description:
  Alternate F1F0 ATPase, F1 subunit epsilon; Produces ATP from ADP in the presence of a proton gradient across the membrane.


ensembl_gene_id: DespoDRAFT_00130
symbol: atpB
gene_biotype: protein_coding
description:
  Alternate F1F0 ATPase, F0 subunit A; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family.


ensembl_gene_id: DespoDRAFT_00131
symbol: atpE
gene_biotype: protein_coding
description:
  ATP synthase, F0 subunit c; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.


ensembl_gene_id: DespoDRAFT_00132
symbol: atpF
gene_biotype: protein_coding
description:
  F0F1-type ATP synthase, beta subunit; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family.


ensembl_gene_id: DespoDRAFT_00133
symbol: atpA
gene_biotype: protein_coding
description:
  Proton translocating ATP synthase, F1 alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.


ensembl_gene_id: DespoDRAFT_00134
symbol: EIM62180.1
gene_biotype: protein_coding
description:
  PFAM: ATP synthase; TIGRFAM: alternate F1F0 ATPase, F1 subunit gamma; ATP synthase, F1 gamma subunit.


ensembl_gene_id: DespoDRAFT_00135
symbol: EIM62181.1
gene_biotype: protein_coding
description:
  Hypothetical protein; PFAM: Pyrimidine dimer DNA glycosylase; Protein of unknown function (DUF1722).


ensembl_gene_id: DespoDRAFT_00136
symbol: nfo
gene_biotype: protein_coding
description:
  Apurinic endonuclease APN1; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.


ensembl_gene_id: DespoDRAFT_00138
symbol: cobT
gene_biotype: protein_coding
description:
  Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).


ensembl_gene_id: DespoDRAFT_00139
symbol: EIM62185.1
gene_biotype: protein_coding
description:
  DNA/RNA helicase, superfamily II; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase.


ensembl_gene_id: DespoDRAFT_00141
symbol: EIM62187.1
gene_biotype: protein_coding
description:
  (NiFe) hydrogenase maturation protein HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.


ensembl_gene_id: DespoDRAFT_00142
symbol: EIM62188.1
gene_biotype: protein_coding
description:
  PFAM: Hydrogenase formation hypA family; TIGRFAM: hydrogenase expression/formation protein HypD; Belongs to the HypD family.


ensembl_gene_id: DespoDRAFT_00143
symbol: EIM62189.1
gene_biotype: protein_coding
description:
  Hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: hydrogenase expression/formation protein HypE.


ensembl_gene_id: DespoDRAFT_00144
symbol: dksA
gene_biotype: protein_coding
description:
  RNA polymerase-binding protein DksA; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.


ensembl_gene_id: DespoDRAFT_00145
symbol: rnc
gene_biotype: protein_coding
description:
  Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.


ensembl_gene_id: DespoDRAFT_00148
symbol: EIM62194.1
gene_biotype: protein_coding
description:
  Putative polymerase with PALM domain, HD hydrolase domain and Zn ribbon; PFAM: Protein of unknown function (DUF342).


ensembl_gene_id: DespoDRAFT_00150
symbol: EIM62195.1
gene_biotype: protein_coding
description:
  Retron-type reverse transcriptase; PFAM: Group II intron, maturase-specific domain; Reverse transcriptase (RNA-dependent DNA polymerase).


ensembl_gene_id: DespoDRAFT_00152
symbol: EIM62197.1
gene_biotype: protein_coding
description:
  ATP:corrinoid adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.


ensembl_gene_id: DespoDRAFT_00156
symbol: hisS
gene_biotype: protein_coding
description:
  PFAM: Anticodon binding domain; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: histidyl-tRNA synthetase.


ensembl_gene_id: DespoDRAFT_00157
symbol: aspS
gene_biotype: protein_coding
description:
  aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.


ensembl_gene_id: DespoDRAFT_00158
symbol: minE
gene_biotype: protein_coding
description:
  Cell division topological specificity factor MinE; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.


ensembl_gene_id: DespoDRAFT_00160
symbol: minC
gene_biotype: protein_coding
description:
  Septum formation inhibitor; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family.


ensembl_gene_id: DespoDRAFT_00161
symbol: EIM62206.1
gene_biotype: protein_coding
description:
  PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain.


ensembl_gene_id: DespoDRAFT_00163
symbol: EIM62208.1
gene_biotype: protein_coding
description:
  3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).


ensembl_gene_id: DespoDRAFT_00167
symbol: bamD
gene_biotype: protein_coding
description:
  Outer membrane assembly lipoprotein YfiO; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: DespoDRAFT_00168
symbol: rpmB
gene_biotype: protein_coding
description:
  PFAM: Ribosomal L28 family; TIGRFAM: ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family.


ensembl_gene_id: DespoDRAFT_00170
symbol: EIM62215.1
gene_biotype: protein_coding
description:
  (p)ppGpp synthetase, RelA/SpoT family; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.


ensembl_gene_id: DespoDRAFT_00171
symbol: proS
gene_biotype: protein_coding
description:
  prolyl-tRNA synthetase, family I; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).


ensembl_gene_id: DespoDRAFT_00172
symbol: ispG
gene_biotype: protein_coding
description:
  1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family.


ensembl_gene_id: DespoDRAFT_00173
symbol: EIM62218.1
gene_biotype: protein_coding
description:
  PFAM: N-6 DNA Methylase; HsdM N-terminal domain; TIGRFAM: type I restriction system adenine methylase (hsdM).


ensembl_gene_id: DespoDRAFT_00181
symbol: EIM62225.1
gene_biotype: protein_coding
description:
  PFAM: Aconitase C-terminal domain; Aconitase family (aconitate hydratase); TIGRFAM: aconitate hydratase, putative, Aquifex type.


ensembl_gene_id: DespoDRAFT_00184
symbol: glk
gene_biotype: protein_coding
description:
  PFAM: Glucokinase; TIGRFAM: glucokinase, proteobacterial type; Belongs to the bacterial glucokinase family.


ensembl_gene_id: DespoDRAFT_00186
symbol: EIM62230.1
gene_biotype: protein_coding
description:
  Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; PFAM: Aminotransferase class IV.


ensembl_gene_id: DespoDRAFT_00187
symbol: EIM62231.1
gene_biotype: protein_coding
description:
  Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.


ensembl_gene_id: DespoDRAFT_00194
symbol: dacA
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.


ensembl_gene_id: DespoDRAFT_00199
symbol: EIM62241.1
gene_biotype: protein_coding
description:
  Membrane-associated lipoprotein involved in thiamine biosynthesis; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. Belongs to the ApbE family.


ensembl_gene_id: DespoDRAFT_00201
symbol: EIM62243.1
gene_biotype: protein_coding
description:
  PAS domain S-box; PFAM: Cache domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; Hpt domain; PAS fold; TIGRFAM: PAS domain S-box.


ensembl_gene_id: DespoDRAFT_00203
symbol: EIM62245.1
gene_biotype: protein_coding
description:
  2-oxoacid:ferredoxin oxidoreductase, gamma subunit; PFAM: Pyruvate ferredoxin/flavodoxin oxidoreductase.


ensembl_gene_id: DespoDRAFT_00210
symbol: glyQS
gene_biotype: protein_coding
description:
  glycyl-tRNA synthetase, dimeric type; Catalyzes the attachment of glycine to tRNA(Gly). Belongs to the class-II aminoacyl-tRNA synthetase family.


ensembl_gene_id: DespoDRAFT_00211
symbol: EIM62252.1
gene_biotype: protein_coding
description:
  Isoleucine patch superfamily enzyme, carbonic anhydrase/acetyltransferase; PFAM: Bacterial transferase hexapeptide (three repeats).


ensembl_gene_id: DespoDRAFT_00215
symbol: EIM62256.1
gene_biotype: protein_coding
description:
  Dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: dihydrolipoamide dehydrogenase.


ensembl_gene_id: DespoDRAFT_00218
symbol: EIM62259.1
gene_biotype: protein_coding
description:
  Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase component; PFAM: 2-oxoacid dehydrogenases acyltransferase (catalytic domain); e3 binding domain; Biotin-requiring enzyme.


ensembl_gene_id: DespoDRAFT_00219
symbol: EIM62260.1
gene_biotype: protein_coding
description:
  Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.


ensembl_gene_id: DespoDRAFT_00220
symbol: pdhA
gene_biotype: protein_coding
description:
  Pyruvate dehydrogenase E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


ensembl_gene_id: DespoDRAFT_00224
symbol: EIM62265.1
gene_biotype: protein_coding
description:
  P-type ATPase, translocating; PFAM: E1-E2 ATPase; Cation transporting ATPase, C-terminus; Cation transporter/ATPase, N-terminus; haloacid dehalogenase-like hydrolase; TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC.


ensembl_gene_id: DespoDRAFT_00230
symbol: EIM62269.1
gene_biotype: protein_coding
description:
  PFAM: Ribosomal protein L11 methyltransferase (PrmA); TIGRFAM: ribosomal protein L11 methyltransferase.


ensembl_gene_id: DespoDRAFT_00233
symbol: mnmE
gene_biotype: protein_coding
description:
  tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.


ensembl_gene_id: DespoDRAFT_00235
symbol: yidC
gene_biotype: protein_coding
description:
  Membrane protein insertase, YidC/Oxa1 family, N-terminal domain; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.


ensembl_gene_id: DespoDRAFT_00236
symbol: EIM62275.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family.


ensembl_gene_id: DespoDRAFT_00237
symbol: rnpA
gene_biotype: protein_coding
description:
  Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.


ensembl_gene_id: DespoDRAFT_00238
symbol: rpmH
gene_biotype: protein_coding
description:
  PFAM: Ribosomal protein L34; TIGRFAM: ribosomal protein L34, bacterial type; Belongs to the bacterial ribosomal protein bL34 family.


ensembl_gene_id: DespoDRAFT_00240
symbol: EIM62279.1
gene_biotype: protein_coding
description:
  PFAM: Uncharacterized protein conserved in bacteria (DUF2344); Radical SAM superfamily; TIGRFAM: radical SAM family uncharacterized protein; radical SAM-linked protein.


ensembl_gene_id: DespoDRAFT_00241
symbol: asnS
gene_biotype: protein_coding
description:
  PFAM: tRNA synthetases class II (D, K and N); OB-fold nucleic acid binding domain; TIGRFAM: asparaginyl-tRNA synthetase.


ensembl_gene_id: DespoDRAFT_00242
symbol: rsgA
gene_biotype: protein_coding
description:
  Ribosome small subunit-dependent GTPase A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.


ensembl_gene_id: DespoDRAFT_00250
symbol: EIM62288.1
gene_biotype: protein_coding
description:
  Phosphoserine phosphatase SerB; PFAM: ACT domain; haloacid dehalogenase-like hydrolase; TIGRFAM: Haloacid Dehalogenase superfamily, subfamily IB, phosphoserine phosphatase-like; phosphoserine phosphatase SerB.


ensembl_gene_id: DespoDRAFT_00253
symbol: queC
gene_biotype: protein_coding
description:
  Queuosine biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.


ensembl_gene_id: DespoDRAFT_00254
symbol: queE
gene_biotype: protein_coding
description:
  Organic radical activating enzyme; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.


ensembl_gene_id: DespoDRAFT_00255
symbol: EIM62293.1
gene_biotype: protein_coding
description:
  Queuosine biosynthesis protein QueD; PFAM: 6-pyruvoyl tetrahydropterin synthase; TIGRFAM: queuosine biosynthesis protein QueD; 6-pyruvoyl tetrahydropterin synthase/QueD family protein.


ensembl_gene_id: DespoDRAFT_00256
symbol: EIM62294.1
gene_biotype: protein_coding
description:
  Homocysteine/selenocysteine methylase (S-methylmethionine-dependent); PFAM: Homocysteine S-methyltransferase.


ensembl_gene_id: DespoDRAFT_00259
symbol: EIM62296.1
gene_biotype: protein_coding
description:
  PFAM: Phosphoribosyl transferase domain; TIGRFAM: hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.


ensembl_gene_id: DespoDRAFT_00260
symbol: EIM62297.1
gene_biotype: protein_coding
description:
  DnaJ-class molecular chaperone with C-terminal Zn finger domain; PFAM: DnaJ C terminal region; DnaJ domain.


ensembl_gene_id: DespoDRAFT_00261
symbol: mnmG
gene_biotype: protein_coding
description:
  Glucose-inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family.


ensembl_gene_id: DespoDRAFT_00272
symbol: glnE
gene_biotype: protein_coding
description:
  Glutamine synthetase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transducti [...]


ensembl_gene_id: DespoDRAFT_00277
symbol: carA
gene_biotype: protein_coding
description:
  PFAM: Carbamoyl-phosphate synthase small chain, CPSase domain; Glutamine amidotransferase class-I; TIGRFAM: carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family.


ensembl_gene_id: DespoDRAFT_00278
symbol: carB
gene_biotype: protein_coding
description:
  Carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; MGS-like domain; Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Carbamoyl-phosphate synthase L chain, N-terminal domain; TIGRFAM: carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family.


ensembl_gene_id: DespoDRAFT_00279
symbol: purF
gene_biotype: protein_coding
description:
  Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.


ensembl_gene_id: DespoDRAFT_00286
symbol: EIM62318.1
gene_biotype: protein_coding
description:
  Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.


ensembl_gene_id: DespoDRAFT_00287
symbol: EIM62319.1
gene_biotype: protein_coding
description:
  PFAM: Putative RNA methylase family UPF0020; THUMP domain; Belongs to the methyltransferase superfamily.


ensembl_gene_id: DespoDRAFT_00290
symbol: EIM62321.1
gene_biotype: protein_coding
description:
  Putative domain HDIG-containing protein; PFAM: Response regulator receiver domain; HDOD domain; TIGRFAM: uncharacterized domain HDIG.


ensembl_gene_id: DespoDRAFT_00291
symbol: EIM62322.1
gene_biotype: protein_coding
description:
  PFAM: Monomeric isocitrate dehydrogenase; TIGRFAM: isocitrate dehydrogenase, NADP-dependent, monomeric type; Belongs to the monomeric-type IDH family.


ensembl_gene_id: DespoDRAFT_00292
symbol: EIM62323.1
gene_biotype: protein_coding
description:
  Lactate dehydrogenase-like oxidoreductase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain.


ensembl_gene_id: DespoDRAFT_00294
symbol: EIM62325.1
gene_biotype: protein_coding
description:
  Transcriptional regulator; PFAM: YsiA-like protein, C-terminal region; Bacterial regulatory proteins, tetR family.


ensembl_gene_id: DespoDRAFT_00296
symbol: panB
gene_biotype: protein_coding
description:
  3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.


ensembl_gene_id: DespoDRAFT_00298
symbol: EIM62329.1
gene_biotype: protein_coding
description:
  Putative Zn-dependent peptidase, insulinase; PFAM: Peptidase M16C associated; Peptidase M16 inactive domain; Insulinase (Peptidase family M16).


ensembl_gene_id: DespoDRAFT_00300
symbol: rsmA
gene_biotype: protein_coding
description:
  Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.


ensembl_gene_id: DespoDRAFT_00303
symbol: pncB
gene_biotype: protein_coding
description:
  Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family.


ensembl_gene_id: DespoDRAFT_00305
symbol: EIM62336.1
gene_biotype: protein_coding
description:
  RRM domain-containing RNA-binding protein; PFAM: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain).


ensembl_gene_id: DespoDRAFT_00314
symbol: EIM62344.1
gene_biotype: protein_coding
description:
  Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.


ensembl_gene_id: DespoDRAFT_00316
symbol: nqrA
gene_biotype: protein_coding
description:
  Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrA; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.


ensembl_gene_id: DespoDRAFT_00317
symbol: nqrB
gene_biotype: protein_coding
description:
  NADH:ubiquinone oxidoreductase, Na(+)-translocating, B subunit; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.


ensembl_gene_id: DespoDRAFT_00318
symbol: nqrC
gene_biotype: protein_coding
description:
  Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrC; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.


ensembl_gene_id: DespoDRAFT_00319
symbol: nqrD
gene_biotype: protein_coding
description:
  NADH:ubiquinone oxidoreductase, Na(+)-translocating, D subunit; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol; Belongs to the NqrDE/RnfAE family.


ensembl_gene_id: DespoDRAFT_00320
symbol: nqrE
gene_biotype: protein_coding
description:
  NADH:ubiquinone oxidoreductase, Na(+)-translocating, E subunit; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol; Belongs to the NqrDE/RnfAE family.


ensembl_gene_id: DespoDRAFT_00321
symbol: nqrF
gene_biotype: protein_coding
description:
  NADH:ubiquinone oxidoreductase, Na(+)-translocating, F subunit; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.


ensembl_gene_id: DespoDRAFT_00323
symbol: EIM62353.1
gene_biotype: protein_coding
description:
  2-polyprenylphenol hydroxylase-like oxidoreductase; PFAM: Oxidoreductase FAD-binding domain; Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B; Oxidoreductase NAD-binding domain.


ensembl_gene_id: DespoDRAFT_00324
symbol: pyrE
gene_biotype: protein_coding
description:
  Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).


ensembl_gene_id: DespoDRAFT_00325
symbol: EIM62355.1
gene_biotype: protein_coding
description:
  Periplasmic component of amino acid ABC-type transporter/signal transduction system; PFAM: Bacterial extracellular solute-binding proteins, family 3.


ensembl_gene_id: DespoDRAFT_00326
symbol: coaX
gene_biotype: protein_coding
description:
  Pantothenate kinase, type III; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.


ensembl_gene_id: DespoDRAFT_00328
symbol: EIM62358.1
gene_biotype: protein_coding
description:
  Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.


ensembl_gene_id: DespoDRAFT_00329
symbol: ftsH
gene_biotype: protein_coding
description:
  ATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family.  In the central section; belongs to the AAA ATPase family.


ensembl_gene_id: DespoDRAFT_00330
symbol: tilS
gene_biotype: protein_coding
description:
  tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.


ensembl_gene_id: DespoDRAFT_00331
symbol: EIM62361.1
gene_biotype: protein_coding
description:
  O-6-methylguanine DNA methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.


ensembl_gene_id: DespoDRAFT_00332
symbol: EIM62362.1
gene_biotype: protein_coding
description:
  Putative dehydrogenase; PFAM: Oxidoreductase family, C-terminal alpha/beta domain; Oxidoreductase family, NAD-binding Rossmann fold.


ensembl_gene_id: DespoDRAFT_00333
symbol: EIM62363.1
gene_biotype: protein_coding
description:
  Isopropylmalate/homocitrate/citramalate synthase; PFAM: LeuA allosteric (dimerisation) domain; HMGL-like; Belongs to the alpha-IPM synthase/homocitrate synthase family.


ensembl_gene_id: DespoDRAFT_00337
symbol: EIM62367.1
gene_biotype: protein_coding
description:
  Kef-type K+ transport system, predicted NAD-binding component; PFAM: TrkA-N domain; Sodium/hydrogen exchanger family; TrkA-C domain; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.


ensembl_gene_id: DespoDRAFT_00338
symbol: EIM62368.1
gene_biotype: protein_coding
description:
  PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.


ensembl_gene_id: DespoDRAFT_00339
symbol: EIM62369.1
gene_biotype: protein_coding
description:
  Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains; PFAM: Response regulator receiver domain; Bacterial regulatory protein, Fis family; Sigma-54 interaction domain.


ensembl_gene_id: DespoDRAFT_00363
symbol: EIM62389.1
gene_biotype: protein_coding
description:
  Type I site-specific deoxyribonuclease, HsdR family; Subunit R is required for both nuclease and ATPase activities, but not for modification.


ensembl_gene_id: DespoDRAFT_00364
symbol: EIM62390.1
gene_biotype: protein_coding
description:
  Regulatory P domain of subtilisin-like proprotein convertases; PFAM: Proprotein convertase P-domain; Subtilase family.


ensembl_gene_id: DespoDRAFT_00366
symbol: EIM62392.1
gene_biotype: protein_coding
description:
  Putative domain HDIG-containing protein; PFAM: HAMP domain; HD domain; TIGRFAM: uncharacterized domain HDIG.


ensembl_gene_id: DespoDRAFT_00367
symbol: EIM62393.1
gene_biotype: protein_coding
description:
  Prepilin-type N-terminal cleavage/methylation domain-containing protein; PFAM: Prokaryotic N-terminal methylation motif; Bacterial type II secretion system protein G; TIGRFAM: general secretion pathway protein G; prepilin-type N-terminal cleavage/methylation domain.


ensembl_gene_id: DespoDRAFT_00369
symbol: pepA
gene_biotype: protein_coding
description:
  Leucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.


ensembl_gene_id: DespoDRAFT_00370
symbol: EIM62396.1
gene_biotype: protein_coding
description:
  A/G-specific adenine glycosylase; PFAM: NUDIX domain; HhH-GPD superfamily base excision DNA repair protein; TIGRFAM: mutator mutT protein; A/G-specific adenine glycosylase.


ensembl_gene_id: DespoDRAFT_00374
symbol: sbcD
gene_biotype: protein_coding
description:
  Exonuclease SbcD; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.


ensembl_gene_id: DespoDRAFT_00377
symbol: EIM62401.1
gene_biotype: protein_coding
description:
  Hypothetical protein; PFAM: YcaO-like family; Tetratricopeptide repeat; TIGRFAM: uncharacterized domain; bacteriocin biosynthesis docking scaffold, SagD family.


ensembl_gene_id: DespoDRAFT_00381
symbol: EIM62405.1
gene_biotype: protein_coding
description:
  PFAM: Molybdopterin guanine dinucleotide synthesis protein B; TIGRFAM: molybdopterin-guanine dinucleotide biosynthesis protein MobB.


ensembl_gene_id: DespoDRAFT_00383
symbol: panC
gene_biotype: protein_coding
description:
  Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.


ensembl_gene_id: DespoDRAFT_00386
symbol: EIM62409.1
gene_biotype: protein_coding
description:
  PFAM: Plasmid encoded toxin Txe; TIGRFAM: toxin-antitoxin system, toxin component, Txe/YoeB family; addiction module toxin, RelE/StbE family.


ensembl_gene_id: DespoDRAFT_00389
symbol: hisH
gene_biotype: protein_coding
description:
  Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF; Belongs to the HisA/HisF family.


ensembl_gene_id: DespoDRAFT_00391
symbol: cheD
gene_biotype: protein_coding
description:
  Chemotaxis protein; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.


ensembl_gene_id: DespoDRAFT_00392
symbol: EIM62415.1
gene_biotype: protein_coding
description:
  Single stranded DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.


ensembl_gene_id: DespoDRAFT_00393
symbol: gyrB
gene_biotype: protein_coding
description:
  DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.


ensembl_gene_id: DespoDRAFT_00394
symbol: EIM62417.1
gene_biotype: protein_coding
description:
  DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]


ensembl_gene_id: DespoDRAFT_00396
symbol: EIM62419.1
gene_biotype: protein_coding
description:
  PFAM: Radical SAM superfamily; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase activating protein.


ensembl_gene_id: DespoDRAFT_00401
symbol: rimO
gene_biotype: protein_coding
description:
  Ribosomal protein S12 methylthiotransferase RimO; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily.


ensembl_gene_id: DespoDRAFT_00402
symbol: EIM62425.1
gene_biotype: protein_coding
description:
  Geranylgeranyl pyrophosphate synthase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.


ensembl_gene_id: DespoDRAFT_00410
symbol: surE
gene_biotype: protein_coding
description:
  5''/3''-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.


ensembl_gene_id: DespoDRAFT_00413
symbol: EIM62435.1
gene_biotype: protein_coding
description:
  Indolepyruvate ferredoxin oxidreductase, alpha/beta subunit; Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.


ensembl_gene_id: DespoDRAFT_00415
symbol: EIM62437.1
gene_biotype: protein_coding
description:
  Coenzyme F390 synthetase; Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).


ensembl_gene_id: DespoDRAFT_00416
symbol: EIM62438.1
gene_biotype: protein_coding
description:
  TRAP-type C4-dicarboxylate transport system, periplasmic component; PFAM: Bacterial extracellular solute-binding protein, family 7.


ensembl_gene_id: DespoDRAFT_00417
symbol: EIM62439.1
gene_biotype: protein_coding
description:
  TRAP-type C4-dicarboxylate transport system, small permease component; PFAM: Tripartite ATP-independent periplasmic transporters, DctQ component.


ensembl_gene_id: DespoDRAFT_00420
symbol: EIM62442.1
gene_biotype: protein_coding
description:
  PFAM: Aminotransferase class-III; TIGRFAM: ornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: DespoDRAFT_00430
symbol: EIM62451.1
gene_biotype: protein_coding
description:
  CheY-like receiver domain-containing protein; PFAM: Pyruvate phosphate dikinase, PEP/pyruvate binding domain.


ensembl_gene_id: DespoDRAFT_00431
symbol: EIM62452.1
gene_biotype: protein_coding
description:
  PFAM: Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.


ensembl_gene_id: DespoDRAFT_00432
symbol: EIM62453.1
gene_biotype: protein_coding
description:
  Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; PFAM: Bacterial regulatory proteins, luxR family.


ensembl_gene_id: DespoDRAFT_00434
symbol: EIM62455.1
gene_biotype: protein_coding
description:
  ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component; PFAM: NMT1/THI5 like.


ensembl_gene_id: DespoDRAFT_00435
symbol: EIM62456.1
gene_biotype: protein_coding
description:
  ABC-type nitrate/sulfonate/bicarbonate transport system, permease component; PFAM: Binding-protein-dependent transport system inner membrane component.


ensembl_gene_id: DespoDRAFT_00439
symbol: EIM62460.1
gene_biotype: protein_coding
description:
  C-terminal processing peptidase; PFAM: Peptidase family S41; PDZ domain (Also known as DHR or GLGF); TIGRFAM: C-terminal peptidase (prc); Belongs to the peptidase S41A family.


ensembl_gene_id: DespoDRAFT_00441
symbol: EIM62462.1
gene_biotype: protein_coding
description:
  Cell division protein; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.


ensembl_gene_id: DespoDRAFT_00444
symbol: tatA
gene_biotype: protein_coding
description:
  Twin arginine-targeting protein translocase, TatA/E family; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.


ensembl_gene_id: DespoDRAFT_00445
symbol: glnD
gene_biotype: protein_coding
description:
  (protein-PII) uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.


ensembl_gene_id: DespoDRAFT_00447
symbol: EIM62468.1
gene_biotype: protein_coding
description:
  PFAM: Glutamine synthetase, catalytic domain; Glutamine synthetase, beta-Grasp domain; TIGRFAM: glutamine synthetase, type I.


ensembl_gene_id: DespoDRAFT_00459
symbol: EIM62478.1
gene_biotype: protein_coding
description:
  PFAM: EAL domain; GGDEF domain; PAS fold; TIGRFAM: PAS domain S-box; diguanylate cyclase (GGDEF) domain.


ensembl_gene_id: DespoDRAFT_00460
symbol: EIM62479.1
gene_biotype: protein_coding
description:
  PFAM: Acetokinase family; Phosphate acetyl/butaryl transferase; TIGRFAM: butyrate kinase; Belongs to the acetokinase family.


ensembl_gene_id: DespoDRAFT_00461
symbol: EIM62480.1
gene_biotype: protein_coding
description:
  acyl-CoA synthetase/AMP-acid ligase; PFAM: Domain of unknown function (DUF3448); AMP-binding enzyme.


ensembl_gene_id: DespoDRAFT_00462
symbol: EIM62481.1
gene_biotype: protein_coding
description:
  ABC-type multidrug transport system, ATPase and permease component; PFAM: ABC transporter; ABC transporter transmembrane region.


ensembl_gene_id: DespoDRAFT_00463
symbol: EIM62482.1
gene_biotype: protein_coding
description:
  ABC-type multidrug transport system, ATPase and permease component; PFAM: ABC transporter transmembrane region; ABC transporter.


ensembl_gene_id: DespoDRAFT_00466
symbol: EIM62485.1
gene_biotype: protein_coding
description:
  Quinolinate synthetase complex, A subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.


ensembl_gene_id: DespoDRAFT_00467
symbol: EIM62486.1
gene_biotype: protein_coding
description:
  Outer membrane lipoprotein-sorting protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).


ensembl_gene_id: DespoDRAFT_00470
symbol: grpE
gene_biotype: protein_coding
description:
  Molecular chaperone GrpE (heat shock protein); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  [...]


ensembl_gene_id: DespoDRAFT_00472
symbol: EIM62490.1
gene_biotype: protein_coding
description:
  Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor.


ensembl_gene_id: DespoDRAFT_00475
symbol: EIM62493.1
gene_biotype: protein_coding
description:
  PFAM: Pyridine nucleotide-disulphide oxidoreductase; NADH:flavin oxidoreductase / NADH oxidase family.


ensembl_gene_id: DespoDRAFT_00476
symbol: EIM62494.1
gene_biotype: protein_coding
description:
  PFAM: Cation efflux family; Dinitrogenase iron-molybdenum cofactor; TIGRFAM: cation diffusion facilitator family transporter; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.


ensembl_gene_id: DespoDRAFT_00477
symbol: EIM62495.1
gene_biotype: protein_coding
description:
  Phosphatidylserine synthase; PFAM: CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: DespoDRAFT_00478
symbol: EIM62496.1
gene_biotype: protein_coding
description:
  Putative radical SAM protein YgiQ; PFAM: Radical SAM superfamily; Radical SAM N-terminal; TIGRFAM: uncharacterized radical SAM protein YgiQ.


ensembl_gene_id: DespoDRAFT_00479
symbol: EIM62497.1
gene_biotype: protein_coding
description:
  Arabinose efflux permease family protein; PFAM: Major Facilitator Superfamily; TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; non-canonical start codon.


ensembl_gene_id: DespoDRAFT_00486
symbol: EIM62504.1
gene_biotype: protein_coding
description:
  PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.


ensembl_gene_id: DespoDRAFT_00489
symbol: EIM62506.1
gene_biotype: protein_coding
description:
  ABC-type transport system, involved in lipoprotein release, permease component; PFAM: Predicted permease.


ensembl_gene_id: DespoDRAFT_00496
symbol: EIM62512.1
gene_biotype: protein_coding
description:
  TIGRFAM: RND family efflux transporter, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: DespoDRAFT_00497
symbol: EIM62513.1
gene_biotype: protein_coding
description:
  ABC-type transport system, involved in lipoprotein release, permease component; PFAM: Predicted permease; manually curated.


ensembl_gene_id: DespoDRAFT_00499
symbol: EIM62515.1
gene_biotype: protein_coding
description:
  PFAM: Outer membrane efflux protein; TIGRFAM: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family.


ensembl_gene_id: DespoDRAFT_00503
symbol: EIM62519.1
gene_biotype: protein_coding
description:
  Dissimilatory sulfite reductase (desulfoviridin), alpha/beta subunit; PFAM: Nitrite and sulphite reductase 4Fe-4S domain; Proto-chlorophyllide reductase 57 kD subunit.


ensembl_gene_id: DespoDRAFT_00505
symbol: EIM62521.1
gene_biotype: protein_coding
description:
  nitrate/TMAO reductase, membrane-bound tetraheme cytochrome c subunit; PFAM: NapC/NirT cytochrome c family, N-terminal region.


ensembl_gene_id: DespoDRAFT_00511
symbol: EIM62527.1
gene_biotype: protein_coding
description:
  Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase component alpha subunit; PFAM: Dehydrogenase E1 component.


ensembl_gene_id: DespoDRAFT_00512
symbol: EIM62528.1
gene_biotype: protein_coding
description:
  Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit; PFAM: Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain.


ensembl_gene_id: DespoDRAFT_00514
symbol: EIM62530.1
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.


ensembl_gene_id: DespoDRAFT_00515
symbol: EIM62531.1
gene_biotype: protein_coding
description:
  Pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; PFAM: domain; Domain of unknown function; Pyruvate ferredoxin/flavodoxin oxidoreductase; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric.


ensembl_gene_id: DespoDRAFT_00519
symbol: EIM62535.1
gene_biotype: protein_coding
description:
  Theronine dehydrogenase-like Zn-dependent dehydrogenase; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase.


ensembl_gene_id: DespoDRAFT_00521
symbol: EIM62537.1
gene_biotype: protein_coding
description:
  Uncharacterized protein involved in formation of curli polymers; PFAM: Curli production assembly/transport component CsgG.


ensembl_gene_id: DespoDRAFT_00523
symbol: EIM62539.1
gene_biotype: protein_coding
description:
  PFAM: HlyD family secretion protein; TIGRFAM: RND family efflux transporter, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: DespoDRAFT_00524
symbol: EIM62540.1
gene_biotype: protein_coding
description:
  PFAM: AcrB/AcrD/AcrF family; TIGRFAM: The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family.


ensembl_gene_id: DespoDRAFT_00530
symbol: EIM62544.1
gene_biotype: protein_coding
description:
  Cytosine deaminase-like metal-dependent hydrolase; PFAM: Amidohydrolase family; TIGRFAM: guanine deaminase.


ensembl_gene_id: DespoDRAFT_00531
symbol: EIM62545.1
gene_biotype: protein_coding
description:
  Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A; PFAM: 2Fe-2S iron-sulfur cluster binding domain; FAD binding domain in molybdopterin dehydrogenase; [2Fe-2S] binding domain; CO dehydrogenase flavoprotein C-terminal domain; TIGRFAM: xanthine dehydrogenase, small subunit.


ensembl_gene_id: DespoDRAFT_00532
symbol: EIM62546.1
gene_biotype: protein_coding
description:
  PFAM: Molybdopterin-binding domain of aldehyde dehydrogenase; Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; TIGRFAM: xanthine dehydrogenase, molybdopterin binding subunit.


ensembl_gene_id: DespoDRAFT_00533
symbol: EIM62547.1
gene_biotype: protein_coding
description:
  PFAM: Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; CBS domain; Glu/Leu/Phe/Val dehydrogenase, dimerisation domain.


ensembl_gene_id: DespoDRAFT_00539
symbol: fliW
gene_biotype: protein_coding
description:
  Hypothetical protein; Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.


ensembl_gene_id: DespoDRAFT_00540
symbol: csrA
gene_biotype: protein_coding
description:
  Carbon storage regulator CsrA; A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'- UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.


ensembl_gene_id: DespoDRAFT_00543
symbol: flgI
gene_biotype: protein_coding
description:
  Flagellar basal-body P-ring protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.


ensembl_gene_id: DespoDRAFT_00544
symbol: flgH
gene_biotype: protein_coding
description:
  Flagellar basal body L-ring protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.


ensembl_gene_id: DespoDRAFT_00546
symbol: EIM62560.1
gene_biotype: protein_coding
description:
  Flagellar basal-body rod protein FlgG; PFAM: Domain of unknown function (DUF1078); Flagella basal body rod protein; TIGRFAM: fagellar hook-basal body proteins; flagellar basal-body rod protein FlgG, Gram-negative bacteria.


ensembl_gene_id: DespoDRAFT_00547
symbol: EIM62561.1
gene_biotype: protein_coding
description:
  Flagellar hook-basal body protein; PFAM: Domain of unknown function (DUF1078); Flagella basal body rod protein; TIGRFAM: fagellar hook-basal body proteins.


ensembl_gene_id: DespoDRAFT_00548
symbol: EIM62562.1
gene_biotype: protein_coding
description:
  Uncharacterized protein, cytoplasmic domain of flagellar protein FhlB like protein; PFAM: FlhB HrpN YscU SpaS Family; TIGRFAM: flhB C-terminus-related protein.


ensembl_gene_id: DespoDRAFT_00553
symbol: EIM62567.1
gene_biotype: protein_coding
description:
  RNA polymerase sigma factor, FliA/WhiG family; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.


ensembl_gene_id: DespoDRAFT_00556
symbol: flhA
gene_biotype: protein_coding
description:
  Flagellar biosynthesis protein FlhA; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.


ensembl_gene_id: DespoDRAFT_00557
symbol: flhB
gene_biotype: protein_coding
description:
  Flagellar biosynthetic protein FlhB; Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the type III secretion exporter family.


ensembl_gene_id: DespoDRAFT_00558
symbol: EIM62572.1
gene_biotype: protein_coding
description:
  Flagellar biosynthetic protein FliR; Role in flagellar biosynthesis. Belongs to the FliR/MopE/SpaR family.


ensembl_gene_id: DespoDRAFT_00561
symbol: EIM62575.1
gene_biotype: protein_coding
description:
  PAS domain S-box; PFAM: Response regulator receiver domain; Bacterial regulatory protein, Fis family; Sigma-54 interaction domain; PAS fold; TIGRFAM: PAS domain S-box; overlaps another CDS with the same product name.


ensembl_gene_id: DespoDRAFT_00562
symbol: EIM62576.1
gene_biotype: protein_coding
description:
  PAS domain S-box; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; His Kinase A (phosphoacceptor) domain; Predicted histidine kinase sensor domain; PAS fold; TIGRFAM: PAS domain S-box; overlaps another CDS with the same product name.


ensembl_gene_id: DespoDRAFT_00563
symbol: fliQ
gene_biotype: protein_coding
description:
  Flagellar biosynthetic protein FliQ; Role in flagellar biosynthesis. Belongs to the FliQ/MopD/SpaQ family.


ensembl_gene_id: DespoDRAFT_00564
symbol: fliP
gene_biotype: protein_coding
description:
  Flagellar biosynthetic protein FliP; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family.


ensembl_gene_id: DespoDRAFT_00566
symbol: EIM62580.1
gene_biotype: protein_coding
description:
  Flagellar motor switch protein FliN; PFAM: Surface presentation of antigens (SPOA); TIGRFAM: flagellar motor switch protein FliN.


ensembl_gene_id: DespoDRAFT_00567
symbol: EIM62581.1
gene_biotype: protein_coding
description:
  PFAM: Surface presentation of antigens (SPOA); Flagellar motor switch protein FliM; TIGRFAM: flagellar motor switch protein FliM.


ensembl_gene_id: DespoDRAFT_00568
symbol: EIM62582.1
gene_biotype: protein_coding
description:
  Flagellar basal body-associated protein; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.


ensembl_gene_id: DespoDRAFT_00570
symbol: trpB
gene_biotype: protein_coding
description:
  Pyridoxal-phosphate dependent TrpB-like enzyme; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.


ensembl_gene_id: DespoDRAFT_00571
symbol: EIM62585.1
gene_biotype: protein_coding
description:
  PAS domain S-box; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; PAS fold; TIGRFAM: PAS domain S-box.


ensembl_gene_id: DespoDRAFT_00572
symbol: EIM62586.1
gene_biotype: protein_coding
description:
  PFAM: Nitrite and sulphite reductase 4Fe-4S domain; Nitrite/Sulfite reductase ferredoxin-like half domain.


ensembl_gene_id: DespoDRAFT_00573
symbol: EIM62587.1
gene_biotype: protein_coding
description:
  PFAM: Bacterial regulatory helix-turn-helix protein, lysR family; LysR substrate binding domain; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: DespoDRAFT_00574
symbol: ilvC
gene_biotype: protein_coding
description:
  Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.


ensembl_gene_id: DespoDRAFT_00587
symbol: lipA
gene_biotype: protein_coding
description:
  Lipoate synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.


ensembl_gene_id: DespoDRAFT_00588
symbol: lipB
gene_biotype: protein_coding
description:
  Lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.


ensembl_gene_id: DespoDRAFT_00591
symbol: EIM62602.1
gene_biotype: protein_coding
description:
  Fumarate hydratase class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.


ensembl_gene_id: DespoDRAFT_00594
symbol: mntP
gene_biotype: protein_coding
description:
  Putative membrane protein; Probably functions as a manganese efflux pump. Belongs to the MntP (TC 9.B.29) family.


ensembl_gene_id: DespoDRAFT_00598
symbol: tpx
gene_biotype: protein_coding
description:
  Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily.


ensembl_gene_id: DespoDRAFT_00600
symbol: EIM62610.1
gene_biotype: protein_coding
description:
  Putative exonuclease of the beta-lactamase fold involved in RNA processing; PFAM: Metallo-beta-lactamase superfamily; RNA-metabolising metallo-beta-lactamase; Beta-Casp domain.


ensembl_gene_id: DespoDRAFT_00603
symbol: EIM62612.1
gene_biotype: protein_coding
description:
  ATPase FliI/YscN family; PFAM: ATP synthase alpha/beta family, beta-barrel domain; ATP synthase alpha/beta family, nucleotide-binding domain; TIGRFAM: ATPase FliI/YscN family.


ensembl_gene_id: DespoDRAFT_00606
symbol: EIM62615.1
gene_biotype: protein_coding
description:
  Flagellar basal-body M-ring protein/flagellar hook-basal body protein FliF; The M ring may be actively involved in energy transduction. Belongs to the FliF family.


ensembl_gene_id: DespoDRAFT_00607
symbol: fliE
gene_biotype: protein_coding
description:
  PFAM: Flagellar hook-basal body complex protein FliE; TIGRFAM: flagellar hook-basal body complex protein FliE.


ensembl_gene_id: DespoDRAFT_00608
symbol: EIM62617.1
gene_biotype: protein_coding
description:
  Flagellar basal-body rod protein FlgC; PFAM: Domain of unknown function (DUF1078); Flagella basal body rod protein; TIGRFAM: flagellar basal-body rod protein FlgC; Belongs to the flagella basal body rod proteins family.


ensembl_gene_id: DespoDRAFT_00609
symbol: EIM62618.1
gene_biotype: protein_coding
description:
  Flagellar basal-body rod protein FlgB; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.


ensembl_gene_id: DespoDRAFT_00612
symbol: EIM62621.1
gene_biotype: protein_coding
description:
  Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains; PFAM: Bacterial regulatory protein, Fis family; Sigma-54 interaction domain.


ensembl_gene_id: DespoDRAFT_00616
symbol: EIM62625.1
gene_biotype: protein_coding
description:
  Putative domain HDIG-containing protein; PFAM: HD domain; GAF domain; Response regulator receiver domain; TIGRFAM: uncharacterized domain HDIG.


ensembl_gene_id: DespoDRAFT_00618
symbol: EIM62627.1
gene_biotype: protein_coding
description:
  PFAM: Pyridoxal-dependent decarboxylase, C-terminal sheet domain; Pyridoxal-dependent decarboxylase, pyridoxal binding domain; TIGRFAM: diaminopimelate decarboxylase.


ensembl_gene_id: DespoDRAFT_00620
symbol: EIM62629.1
gene_biotype: protein_coding
description:
  tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.


ensembl_gene_id: DespoDRAFT_00623
symbol: uvrA
gene_biotype: protein_coding
description:
  Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.


ensembl_gene_id: DespoDRAFT_00630
symbol: leuB
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.


ensembl_gene_id: DespoDRAFT_00633
symbol: fumC
gene_biotype: protein_coding
description:
  Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.


ensembl_gene_id: DespoDRAFT_00636
symbol: cobD
gene_biotype: protein_coding
description:
  Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.


ensembl_gene_id: DespoDRAFT_00637
symbol: EIM62642.1
gene_biotype: protein_coding
description:
  PLP-dependent enzyme, histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase; PFAM: Aminotransferase class I and II.


ensembl_gene_id: DespoDRAFT_00638
symbol: cobS
gene_biotype: protein_coding
description:
  Cobalamin-5-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.


ensembl_gene_id: DespoDRAFT_00639
symbol: EIM62644.1
gene_biotype: protein_coding
description:
  Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.


ensembl_gene_id: DespoDRAFT_00647
symbol: EIM62651.1
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta); PFAM: Carboxyl transferase domain.


ensembl_gene_id: DespoDRAFT_00652
symbol: EIM62655.1
gene_biotype: protein_coding
description:
  ABC-type Fe3+-hydroxamate transport system, periplasmic component; PFAM: Periplasmic binding protein.


ensembl_gene_id: DespoDRAFT_00656
symbol: EIM62659.1
gene_biotype: protein_coding
description:
  Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains; PFAM: Bacterial regulatory protein, Fis family; Sigma-54 interaction domain.


ensembl_gene_id: DespoDRAFT_00659
symbol: radA
gene_biotype: protein_coding
description:
  DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.


ensembl_gene_id: DespoDRAFT_00660
symbol: rlmE
gene_biotype: protein_coding
description:
  23S rRNA methylase; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.


ensembl_gene_id: DespoDRAFT_00669
symbol: EIM62671.1
gene_biotype: protein_coding
description:
  GTP-binding protein TypA/BipA; PFAM: Elongation factor Tu domain 2; Elongation factor G C-terminus; Elongation factor Tu GTP binding domain; TIGRFAM: GTP-binding protein TypA/BipA; small GTP-binding protein domain.


ensembl_gene_id: DespoDRAFT_00678
symbol: speE
gene_biotype: protein_coding
description:
  Putative spermidine synthase with an N-terminal membrane domain; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.


ensembl_gene_id: DespoDRAFT_00679
symbol: priA
gene_biotype: protein_coding
description:
  Primosomal protein N'; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.


ensembl_gene_id: DespoDRAFT_00688
symbol: EIM62685.1
gene_biotype: protein_coding
description:
  Penicillin-binding protein, 1A family; PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase; S1 RNA binding domain; TIGRFAM: penicillin-binding protein, 1A family.


ensembl_gene_id: DespoDRAFT_00690
symbol: hisI
gene_biotype: protein_coding
description:
  phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.


ensembl_gene_id: DespoDRAFT_00691
symbol: hisG
gene_biotype: protein_coding
description:
  ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily.


ensembl_gene_id: DespoDRAFT_00693
symbol: engB
gene_biotype: protein_coding
description:
  Ribosome biogenesis GTP-binding protein YsxC/EngB; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.


ensembl_gene_id: DespoDRAFT_00694
symbol: era
gene_biotype: protein_coding
description:
  GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.


ensembl_gene_id: DespoDRAFT_00697
symbol: queF
gene_biotype: protein_coding
description:
  7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.


ensembl_gene_id: DespoDRAFT_00698
symbol: EIM62694.1
gene_biotype: protein_coding
description:
  Putative TIM-barrel protein, nifR3 family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.


ensembl_gene_id: DespoDRAFT_00705
symbol: corA
gene_biotype: protein_coding
description:
  Magnesium Mg(2+) and cobalt Co(2+) transport protein CorA; Mediates influx of magnesium ions. Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.


ensembl_gene_id: DespoDRAFT_00710
symbol: EIM62704.1
gene_biotype: protein_coding
description:
  PEP-CTERM putative exosortase interaction domain-containing protein; PFAM: PEP-CTERM motif; TIGRFAM: PEP-CTERM protein sorting domain.


ensembl_gene_id: DespoDRAFT_00722
symbol: EIM62716.1
gene_biotype: protein_coding
description:
  PFAM: Bacterial DNA-binding protein; TIGRFAM: integration host factor, beta subunit; Belongs to the bacterial histone-like protein family.


ensembl_gene_id: DespoDRAFT_00728
symbol: EIM62719.1
gene_biotype: protein_coding
description:
  SOS regulatory protein LexA; Represses a number of genes involved in the response to DNA damage (SOS response).


ensembl_gene_id: DespoDRAFT_00731
symbol: EIM62722.1
gene_biotype: protein_coding
description:
  ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA; PFAM: ABC transporter.


ensembl_gene_id: DespoDRAFT_00735
symbol: EIM62725.1
gene_biotype: protein_coding
description:
  acetyl-CoA acetyltransferase; PFAM: Thiolase, C-terminal domain; Thiolase, N-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases; Belongs to the thiolase-like superfamily. Thiolase family.


ensembl_gene_id: DespoDRAFT_00736
symbol: EIM62726.1
gene_biotype: protein_coding
description:
  PFAM: Enoyl-CoA hydratase/isomerase family; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain.


ensembl_gene_id: DespoDRAFT_00739
symbol: EIM62729.1
gene_biotype: protein_coding
description:
  PAS domain S-box; PFAM: HAMP domain; Cache domain; Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box.


ensembl_gene_id: DespoDRAFT_00744
symbol: EIM62733.1
gene_biotype: protein_coding
description:
  Polyferredoxin, heterodixulfide reductase subunit A; PFAM: Methyl-viologen-reducing hydrogenase, delta subunit.


ensembl_gene_id: DespoDRAFT_00747
symbol: EIM62736.1
gene_biotype: protein_coding
description:
  PFAM: Adenosine-5'-phosphosulfate reductase beta subunit; TIGRFAM: adenosine phosphosulphate reductase, beta subunit.


ensembl_gene_id: DespoDRAFT_00749
symbol: EIM62738.1
gene_biotype: protein_coding
description:
  Dehydrogenase of unknown specificity; Short-chain alcohol dehydrogenase like; PFAM: short chain dehydrogenase.


ensembl_gene_id: DespoDRAFT_00750
symbol: EIM62739.1
gene_biotype: protein_coding
description:
  Transcriptional regulator; PFAM: LysR substrate binding domain; Bacterial regulatory helix-turn-helix protein, lysR family; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: DespoDRAFT_00751
symbol: EIM62740.1
gene_biotype: protein_coding
description:
  Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.


ensembl_gene_id: DespoDRAFT_00753
symbol: EIM62742.1
gene_biotype: protein_coding
description:
  PFAM: HD domain; TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase, putative; Belongs to the dGTPase family. Type 2 subfamily.


ensembl_gene_id: DespoDRAFT_00755
symbol: infC
gene_biotype: protein_coding
description:
  Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.


ensembl_gene_id: DespoDRAFT_00756
symbol: rpmI
gene_biotype: protein_coding
description:
  PFAM: Ribosomal protein L35; TIGRFAM: ribosomal protein L35; Belongs to the bacterial ribosomal protein bL35 family.


ensembl_gene_id: DespoDRAFT_00757
symbol: rplT
gene_biotype: protein_coding
description:
  Ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.


ensembl_gene_id: DespoDRAFT_00758
symbol: pheS
gene_biotype: protein_coding
description:
  phenylalanyl-tRNA synthetase, alpha subunit; PFAM: tRNA synthetases class II core domain (F); Aminoacyl tRNA synthetase class II, N-terminal domain; TIGRFAM: phenylalanyl-tRNA synthetase, alpha subunit; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.


ensembl_gene_id: DespoDRAFT_00759
symbol: pheT
gene_biotype: protein_coding
description:
  phenylalanyl-tRNA synthetase, beta subunit; PFAM: tRNA synthetase B5 domain; Ferredoxin-fold anticodon binding domain; B3/4 domain; Putative tRNA binding domain; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit, non-spirochete bacterial; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.


ensembl_gene_id: DespoDRAFT_00761
symbol: rimP
gene_biotype: protein_coding
description:
  Hypothetical protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.


ensembl_gene_id: DespoDRAFT_00762
symbol: nusA
gene_biotype: protein_coding
description:
  Transcription termination factor NusA; Participates in both transcription termination and antitermination.


ensembl_gene_id: DespoDRAFT_00763
symbol: infB
gene_biotype: protein_coding
description:
  Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.


ensembl_gene_id: DespoDRAFT_00764
symbol: rbfA
gene_biotype: protein_coding
description:
  Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.


ensembl_gene_id: DespoDRAFT_00765
symbol: truB
gene_biotype: protein_coding
description:
  tRNA pseudouridine 55 synthase; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.


ensembl_gene_id: DespoDRAFT_00766
symbol: rpsO
gene_biotype: protein_coding
description:
  Ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.


ensembl_gene_id: DespoDRAFT_00767
symbol: pnp
gene_biotype: protein_coding
description:
  Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.


ensembl_gene_id: DespoDRAFT_00772
symbol: EIM62760.1
gene_biotype: protein_coding
description:
  PFAM: Type I restriction enzyme R protein N terminus (HSDR_N); Domain of unknown function (DUF3559); Type III restriction enzyme, res subunit.


ensembl_gene_id: DespoDRAFT_00774
symbol: EIM62762.1
gene_biotype: protein_coding
description:
  Type I restriction-modification system methyltransferase subunit; PFAM: N-6 DNA Methylase; HsdM N-terminal domain.


ensembl_gene_id: DespoDRAFT_00781
symbol: EIM62768.1
gene_biotype: protein_coding
description:
  Cation/multidrug efflux pump; PFAM: AcrB/AcrD/AcrF family; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: DespoDRAFT_00787
symbol: EIM62773.1
gene_biotype: protein_coding
description:
  Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL-like protein; PFAM: Molybdopterin-binding domain of aldehyde dehydrogenase; 2Fe-2S iron-sulfur cluster binding domain; Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; [2Fe-2S] binding domain.


ensembl_gene_id: DespoDRAFT_00791
symbol: EIM62775.1
gene_biotype: protein_coding
description:
  Methylase involved in ubiquinone/menaquinone biosynthesis; PFAM: ubiE/COQ5 methyltransferase family.


ensembl_gene_id: DespoDRAFT_00798
symbol: EIM62782.1
gene_biotype: protein_coding
description:
  PFAM: GGDEF domain; HDOD domain; TIGRFAM: diguanylate cyclase (GGDEF) domain; uncharacterized domain HDIG.


ensembl_gene_id: DespoDRAFT_00799
symbol: EIM62783.1
gene_biotype: protein_coding
description:
  PFAM: Hydrogenase maturation protease; TIGRFAM: hydrogenase expression/formation protein; hydrogenase maturation protease.


ensembl_gene_id: DespoDRAFT_00801
symbol: EIM62785.1
gene_biotype: protein_coding
description:
  Hydrogenase (NiFe) small subunit HydA; PFAM: NADH ubiquinone oxidoreductase, 20 Kd subunit; TIGRFAM: hydrogenase (NiFe) small subunit (hydA).


ensembl_gene_id: DespoDRAFT_00803
symbol: EIM62787.1
gene_biotype: protein_coding
description:
  PFAM: Thioesterase superfamily; TIGRFAM: acyl-CoA thioester hydrolase, YbgC/YbaW family; tol-pal system-associated acyl-CoA thioesterase.


ensembl_gene_id: DespoDRAFT_00806
symbol: ackA
gene_biotype: protein_coding
description:
  Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.


ensembl_gene_id: DespoDRAFT_00807
symbol: crcB
gene_biotype: protein_coding
description:
  crcB protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.


ensembl_gene_id: DespoDRAFT_00810
symbol: acsA
gene_biotype: protein_coding
description:
  acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.


ensembl_gene_id: DespoDRAFT_00813
symbol: EIM62797.1
gene_biotype: protein_coding
description:
  Fe-S-cluster-containing hydrogenase subunit; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence.


ensembl_gene_id: DespoDRAFT_00822
symbol: EIM62806.1
gene_biotype: protein_coding
description:
  PFAM: Aconitase family (aconitate hydratase); TIGRFAM: 3-isopropylmalate dehydratase, large subunit; homoaconitate hydratase family protein; Belongs to the aconitase/IPM isomerase family.


ensembl_gene_id: DespoDRAFT_00823
symbol: EIM62807.1
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.


ensembl_gene_id: DespoDRAFT_00830
symbol: nadK
gene_biotype: protein_coding
description:
  Putative sugar kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.


ensembl_gene_id: DespoDRAFT_00831
symbol: polA
gene_biotype: protein_coding
description:
  DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.


ensembl_gene_id: DespoDRAFT_00833
symbol: purN
gene_biotype: protein_coding
description:
  Phosphoribosylglycinamide formyltransferase, formyltetrahydrofolate-dependent; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.


ensembl_gene_id: DespoDRAFT_00834
symbol: EIM62817.1
gene_biotype: protein_coding
description:
  Putative signal transduction protein containing EAL and modified HD-GYP domains; PFAM: EAL domain; HDOD domain.


ensembl_gene_id: DespoDRAFT_00845
symbol: EIM62825.1
gene_biotype: protein_coding
description:
  PAS domain S-box; PFAM: Bacterial regulatory protein, Fis family; Sigma-54 interaction domain; PAS fold; TIGRFAM: PAS domain S-box.


ensembl_gene_id: DespoDRAFT_00846
symbol: EIM62826.1
gene_biotype: protein_coding
description:
  PFAM: Acyl-CoA dehydrogenase N terminal; Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, middle domain; Acyl-CoA dehydrogenase, N-terminal domain.


ensembl_gene_id: DespoDRAFT_00848
symbol: EIM62828.1
gene_biotype: protein_coding
description:
  PFAM: 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain.


ensembl_gene_id: DespoDRAFT_00854
symbol: EIM62834.1
gene_biotype: protein_coding
description:
  Phosphomannomutase; PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; Phosphoglucomutase/phosphomannomutase, C-terminal domain; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I.


ensembl_gene_id: DespoDRAFT_00855
symbol: uppP
gene_biotype: protein_coding
description:
  Putative bacitracin resistance protein; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.


ensembl_gene_id: DespoDRAFT_00857
symbol: EIM62837.1
gene_biotype: protein_coding
description:
  DnaK suppressor protein; PFAM: Prokaryotic dksA/traR C4-type zinc finger; TIGRFAM: RNA polymerase-binding protein DksA.


ensembl_gene_id: DespoDRAFT_00858
symbol: dapL
gene_biotype: protein_coding
description:
  LL-diaminopimelate aminotransferase; Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL- diaminopimelate.


ensembl_gene_id: DespoDRAFT_00861
symbol: EIM62841.1
gene_biotype: protein_coding
description:
  Glutamate synthase family protein; PFAM: 4Fe-4S binding domain; Conserved region in glutamate synthase; Belongs to the glutamate synthase family.


ensembl_gene_id: DespoDRAFT_00862
symbol: EIM62842.1
gene_biotype: protein_coding
description:
  NADPH-dependent glutamate synthase beta chain-like oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; GXGXG motif.


ensembl_gene_id: DespoDRAFT_00863
symbol: EIM62843.1
gene_biotype: protein_coding
description:
  Bacteriocin propeptide, TIGR03798 family; PFAM: Nitrogen fixation protein of unknown function; TIGRFAM: nif11-like leader peptide domain.


ensembl_gene_id: DespoDRAFT_00864
symbol: EIM62844.1
gene_biotype: protein_coding
description:
  PFAM: Bacterial extracellular solute-binding protein; TIGRFAM: molybdenum ABC transporter, periplasmic molybdate-binding protein.


ensembl_gene_id: DespoDRAFT_00865
symbol: EIM62845.1
gene_biotype: protein_coding
description:
  Molybdate ABC transporter, permease protein; Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: DespoDRAFT_00866
symbol: EIM62846.1
gene_biotype: protein_coding
description:
  Molybdenum ABC transporter, ATP-binding protein; Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Molybdate importer (TC 3.A.1.8) family.


ensembl_gene_id: DespoDRAFT_00867
symbol: EIM62847.1
gene_biotype: protein_coding
description:
  CoA-substrate-specific enzyme activase, putative; PFAM: 2-hydroxyglutaryl-CoA dehydratase, D-component; BadF/BadG/BcrA/BcrD ATPase family; CoA enzyme activase uncharacterised domain (DUF2229); TIGRFAM: CoA-substrate-specific enzyme activase, putative.


ensembl_gene_id: DespoDRAFT_00872
symbol: htpX
gene_biotype: protein_coding
description:
  Zn-dependent protease with chaperone function; PFAM: Peptidase family M48; Belongs to the peptidase M48B family.


ensembl_gene_id: DespoDRAFT_00875
symbol: EIM62854.1
gene_biotype: protein_coding
description:
  1,4-alpha-glucan branching enzyme; PFAM: Carbohydrate-binding module 48 (Isoamylase N-terminal domain).


ensembl_gene_id: DespoDRAFT_00876
symbol: EIM62855.1
gene_biotype: protein_coding
description:
  Glycogen/starch/alpha-glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.


ensembl_gene_id: DespoDRAFT_00877
symbol: EIM62856.1
gene_biotype: protein_coding
description:
  1,4-alpha-glucan branching enzyme; PFAM: Alpha amylase, C-terminal all-beta domain; Carbohydrate-binding module 48 (Isoamylase N-terminal domain); Alpha amylase, catalytic domain.


ensembl_gene_id: DespoDRAFT_00879
symbol: EIM62858.1
gene_biotype: protein_coding
description:
  Glycogen debranching enzyme; PFAM: Amylo-alpha-1,6-glucosidase; Glycogen debranching enzyme N terminal; Alpha amylase, catalytic domain; TIGRFAM: glycogen debranching enzyme, archaeal type, putative.


ensembl_gene_id: DespoDRAFT_00880
symbol: asd
gene_biotype: protein_coding
description:
  Aspartate-semialdehyde dehydrogenase, gamma-proteobacterial; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.


ensembl_gene_id: DespoDRAFT_00886
symbol: EIM62863.1
gene_biotype: protein_coding
description:
  Putative NAD(P)H quinone oxidoreductase, PIG3 family; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; TIGRFAM: putative NAD(P)H quinone oxidoreductase, PIG3 family.


ensembl_gene_id: DespoDRAFT_00889
symbol: EIM62866.1
gene_biotype: protein_coding
description:
  PFAM: AcrB/AcrD/AcrF family; Outer membrane efflux protein; TIGRFAM: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: DespoDRAFT_00895
symbol: EIM62872.1
gene_biotype: protein_coding
description:
  Cobalamin biosynthesis protein CbiK, Co2+ chelatase; Catalyzes the insertion of Co(2+) into sirohydrochlorin. Belongs to the CbiK family.


ensembl_gene_id: DespoDRAFT_00896
symbol: EIM62873.1
gene_biotype: protein_coding
description:
  ABC-type Fe3+-siderophore transport system, permease component; PFAM: FecCD transport family; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: DespoDRAFT_00899
symbol: cbiA
gene_biotype: protein_coding
description:
  Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.


ensembl_gene_id: DespoDRAFT_00901
symbol: EIM62878.1
gene_biotype: protein_coding
description:
  Precorrin-2 C20-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family.


ensembl_gene_id: DespoDRAFT_00903
symbol: cbiD
gene_biotype: protein_coding
description:
  Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.


ensembl_gene_id: DespoDRAFT_00909
symbol: EIM62886.1
gene_biotype: protein_coding
description:
  PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit.


ensembl_gene_id: DespoDRAFT_00912
symbol: EIM62889.1
gene_biotype: protein_coding
description:
  Precorrin-4 C11-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-4 C11-methyltransferase; Belongs to the precorrin methyltransferase family.


ensembl_gene_id: DespoDRAFT_00913
symbol: EIM62890.1
gene_biotype: protein_coding
description:
  PFAM: Cobalamin synthesis G C-terminus; Cobalamin biosynthesis central region; Cobalamin synthesis G N-terminal.


ensembl_gene_id: DespoDRAFT_00914
symbol: EIM62891.1
gene_biotype: protein_coding
description:
  precorrin-3B C17-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-3B C17-methyltransferase.


ensembl_gene_id: DespoDRAFT_00915
symbol: cobQ
gene_biotype: protein_coding
description:
  Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.


ensembl_gene_id: DespoDRAFT_00922
symbol: EIM62899.1
gene_biotype: protein_coding
description:
  Molybdopterin biosynthesis enzyme; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.


ensembl_gene_id: DespoDRAFT_00923
symbol: EIM62900.1
gene_biotype: protein_coding
description:
  Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains; PFAM: Response regulator receiver domain; Sigma-54 interaction domain.


ensembl_gene_id: DespoDRAFT_00924
symbol: EIM62901.1
gene_biotype: protein_coding
description:
  PAS domain S-box; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; TIGRFAM: PAS domain S-box.


ensembl_gene_id: DespoDRAFT_00929
symbol: EIM62906.1
gene_biotype: protein_coding
description:
  NADPH-dependent glutamate synthase beta chain-like oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase.


ensembl_gene_id: DespoDRAFT_00930
symbol: EIM62907.1
gene_biotype: protein_coding
description:
  Fe-S-cluster-containing hydrogenase subunit; PFAM: 4Fe-4S binding domain; TIGRFAM: DMSO reductase, iron-sulfur subunit.


ensembl_gene_id: DespoDRAFT_00931
symbol: EIM62908.1
gene_biotype: protein_coding
description:
  Anaerobic dehydrogenase, typically selenocysteine-containing; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; Molybdopterin oxidoreductase Fe4S4 domain; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: DespoDRAFT_00933
symbol: EIM62910.1
gene_biotype: protein_coding
description:
  PFAM: Alanine dehydrogenase/PNT, C-terminal domain; Alanine dehydrogenase/PNT, N-terminal domain; TIGRFAM: alanine dehydrogenase; Belongs to the AlaDH/PNT family.


ensembl_gene_id: DespoDRAFT_00934
symbol: EIM62911.1
gene_biotype: protein_coding
description:
  Putative SAM-dependent methyltransferase; PFAM: S-adenosylmethionine-dependent methyltransferase; Belongs to the methyltransferase superfamily.


ensembl_gene_id: DespoDRAFT_00940
symbol: EIM62917.1
gene_biotype: protein_coding
description:
  P-loop ATPase, MinD superfamily; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain; 4Fe-4S binding domain; overlaps another CDS with the same product name.


ensembl_gene_id: DespoDRAFT_00941
symbol: EIM62918.1
gene_biotype: protein_coding
description:
  P-loop ATPase, MinD superfamily; PFAM: 4Fe-4S binding domain; CobQ/CobB/MinD/ParA nucleotide binding domain; overlaps another CDS with the same product name.


ensembl_gene_id: DespoDRAFT_00943
symbol: EIM62920.1
gene_biotype: protein_coding
description:
  Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP).


ensembl_gene_id: DespoDRAFT_00953
symbol: EIM62930.1
gene_biotype: protein_coding
description:
  Putative RNA-binding protein containing KH domain, possibly ribosomal protein; PFAM: CRS1 / YhbY (CRM) domain; TIGRFAM: putative RNA-binding protein, YhbY family.


ensembl_gene_id: DespoDRAFT_00955
symbol: EIM62932.1
gene_biotype: protein_coding
description:
  GTP-binding protein YchF; PFAM: Protein of unknown function (DUF933); TIGRFAM: GTP-binding protein YchF.


ensembl_gene_id: DespoDRAFT_00957
symbol: EIM62934.1
gene_biotype: protein_coding
description:
  Molybdenum cofactor synthesis domain protein; May be involved in the biosynthesis of molybdopterin. Belongs to the MoaB/Mog family.


ensembl_gene_id: DespoDRAFT_00958
symbol: pyrR
gene_biotype: protein_coding
description:
  Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.


ensembl_gene_id: DespoDRAFT_00959
symbol: mobA
gene_biotype: protein_coding
description:
  Molybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family.


ensembl_gene_id: DespoDRAFT_00961
symbol: moaC
gene_biotype: protein_coding
description:
  Molybdenum cofactor biosynthesis protein MoaC; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.


ensembl_gene_id: DespoDRAFT_00965
symbol: EIM62942.1
gene_biotype: protein_coding
description:
  PFAM: CHASE2 domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain.


ensembl_gene_id: DespoDRAFT_00972
symbol: EIM62949.1
gene_biotype: protein_coding
description:
  Phosphate transport system regulatory protein PhoU; Plays a role in the regulation of phosphate uptake.


ensembl_gene_id: DespoDRAFT_00974
symbol: EIM62951.1
gene_biotype: protein_coding
description:
  PAS domain S-box; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box.


ensembl_gene_id: DespoDRAFT_00988
symbol: EIM62964.1
gene_biotype: protein_coding
description:
  DNA/RNA helicase, superfamily II, SNF2 family; PFAM: Helicase conserved C-terminal domain; SNF2 family N-terminal domain.


ensembl_gene_id: DespoDRAFT_00994
symbol: EIM62970.1
gene_biotype: protein_coding
description:
  ABC-type transport system involved in cytochrome c biogenesis, permease component; PFAM: Cytochrome C assembly protein; TIGRFAM: cytochrome c-type biogenesis protein CcsB.


ensembl_gene_id: DespoDRAFT_00995
symbol: hemA
gene_biotype: protein_coding
description:
  glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).


ensembl_gene_id: DespoDRAFT_00996
symbol: EIM62972.1
gene_biotype: protein_coding
description:
  Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).


ensembl_gene_id: DespoDRAFT_01000
symbol: EIM62975.1
gene_biotype: protein_coding
description:
  ABC-type Fe3+ transport system, permease component; PFAM: Binding-protein-dependent transport system inner membrane component.


ensembl_gene_id: DespoDRAFT_01004
symbol: EIM62979.1
gene_biotype: protein_coding
description:
  PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; His Kinase A (phosphoacceptor) domain.


ensembl_gene_id: DespoDRAFT_01006
symbol: EIM62981.1
gene_biotype: protein_coding
description:
  Hypothetical protein; PFAM: Uncharacterized BCR, YitT family COG1284; Uncharacterized protein conserved in bacteria (DUF2179).


ensembl_gene_id: DespoDRAFT_01007
symbol: EIM62982.1
gene_biotype: protein_coding
description:
  DNA/RNA helicase, superfamily II, SNF2 family; PFAM: SNF2 Helicase protein; SNF2 family N-terminal domain.


ensembl_gene_id: DespoDRAFT_01008
symbol: EIM62983.1
gene_biotype: protein_coding
description:
  DNA-methyltransferase Dcm; PFAM: C-5 cytosine-specific DNA methylase; TIGRFAM: DNA-methyltransferase (dcm).


ensembl_gene_id: DespoDRAFT_01009
symbol: EIM62984.1
gene_biotype: protein_coding
description:
  DNA mismatch endonuclease Vsr; May nick specific sequences that contain T:G mispairs resulting from m5C-deamination.


ensembl_gene_id: DespoDRAFT_01022
symbol: EIM62995.1
gene_biotype: protein_coding
description:
  Putative Zn-dependent protease; PFAM: Peptidase family M48; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence.


ensembl_gene_id: DespoDRAFT_01023
symbol: EIM62996.1
gene_biotype: protein_coding
description:
  PFAM: Bacterial type II secretion system protein F domain; TIGRFAM: general secretion pathway protein F.


ensembl_gene_id: DespoDRAFT_01029
symbol: EIM63002.1
gene_biotype: protein_coding
description:
  Bacterial nucleoid DNA-binding protein; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.


ensembl_gene_id: DespoDRAFT_01030
symbol: EIM63003.1
gene_biotype: protein_coding
description:
  PFAM: Lyase; Adenylosuccinate lyase C-terminal; TIGRFAM: adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.


ensembl_gene_id: DespoDRAFT_01032
symbol: EIM63005.1
gene_biotype: protein_coding
description:
  PFAM: Trp repressor protein; TIGRFAM: TrpR-related protein YerC/YecD; trp operon repressor, proteobacterial.


ensembl_gene_id: DespoDRAFT_01037
symbol: EIM63009.1
gene_biotype: protein_coding
description:
  Putative membrane protein; PFAM: Ribonuclease BN-like family; TIGRFAM: YihY family protein (not ribonuclease BN).


ensembl_gene_id: DespoDRAFT_01040
symbol: aat
gene_biotype: protein_coding
description:
  leucyl/phenylalanyl-tRNA--protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.


ensembl_gene_id: DespoDRAFT_01041
symbol: EIM63013.1
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease ATP-binding subunit clpA; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; Clp amino terminal domain; ATPase family associated with various cellular activities (AAA); TIGRFAM: ATP-dependent Clp protease ATP-binding subunit clpA; Belongs to the ClpA/ClpB family.


ensembl_gene_id: DespoDRAFT_01042
symbol: clpS
gene_biotype: protein_coding
description:
  Hypothetical protein; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family.


ensembl_gene_id: DespoDRAFT_01043
symbol: secA
gene_biotype: protein_coding
description:
  Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family.


ensembl_gene_id: DespoDRAFT_01045
symbol: argC
gene_biotype: protein_coding
description:
  N-acetyl-gamma-glutamyl-phosphate reductase, common form; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.


ensembl_gene_id: DespoDRAFT_01048
symbol: EIM63020.1
gene_biotype: protein_coding
description:
  TRAP transporter, 4TM/12TM fusion protein; PFAM: Domain of unknown function (DUF3394); DctM-like transporters; TIGRFAM: TRAP transporter, 4TM/12TM fusion protein.


ensembl_gene_id: DespoDRAFT_01056
symbol: EIM63027.1
gene_biotype: protein_coding
description:
  ABC-type uncharacterized transport system, periplasmic component; PFAM: ABC transporter substrate binding protein.


ensembl_gene_id: DespoDRAFT_01060
symbol: EIM63031.1
gene_biotype: protein_coding
description:
  Serine phosphatase RsbU, regulator of sigma subunit; PFAM: HAMP domain; Stage II sporulation protein E (SpoIIE).


ensembl_gene_id: DespoDRAFT_01065
symbol: EIM63036.1
gene_biotype: protein_coding
description:
  ATPase involved in chromosome partitioning; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain; manually curated.


ensembl_gene_id: DespoDRAFT_01066
symbol: EIM63037.1
gene_biotype: protein_coding
description:
  Beta-hydroxyacid dehydrogenase, 3-hydroxyisobutyrate dehydrogenase; PFAM: NAD binding domain of 6-phosphogluconate dehydrogenase.


ensembl_gene_id: DespoDRAFT_01068
symbol: EIM63039.1
gene_biotype: protein_coding
description:
  PFAM: Major Facilitator Superfamily; TIGRFAM: drug resistance transporter, Bcr/CflA subfamily; Multidrug resistance protein.


ensembl_gene_id: DespoDRAFT_01070
symbol: dinB
gene_biotype: protein_coding
description:
  nucleotidyltransferase/DNA polymerase involved in DNA repair; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. Belongs to the DNA polymerase type-Y family.


ensembl_gene_id: DespoDRAFT_01071
symbol: EIM63042.1
gene_biotype: protein_coding
description:
  ABC-type dipeptide transport system, periplasmic component; PFAM: Bacterial extracellular solute-binding proteins, family 5 Middle.


ensembl_gene_id: DespoDRAFT_01072
symbol: EIM63043.1
gene_biotype: protein_coding
description:
  PFAM: ABC transporter; Oligopeptide/dipeptide transporter, C-terminal region; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Belongs to the ABC transporter superfamily.


ensembl_gene_id: DespoDRAFT_01080
symbol: EIM63051.1
gene_biotype: protein_coding
description:
  Putative kinase, galactokinase/mevalonate kinase; PFAM: GHMP kinases C terminal; GHMP kinases N terminal domain.


ensembl_gene_id: DespoDRAFT_01083
symbol: ligA
gene_biotype: protein_coding
description:
  DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.


ensembl_gene_id: DespoDRAFT_01084
symbol: ftsY
gene_biotype: protein_coding
description:
  Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.


ensembl_gene_id: DespoDRAFT_01086
symbol: EIM63057.1
gene_biotype: protein_coding
description:
  6-phosphofructokinase; PFAM: Phosphofructokinase; TIGRFAM: diphosphate--fructose-6-phosphate 1-phosphotransferase.


ensembl_gene_id: DespoDRAFT_01087
symbol: EIM63058.1
gene_biotype: protein_coding
description:
  PFAM: Radical SAM superfamily; TIGRFAM: putative heme d1 biosynthesis radical SAM protein NirJ2; radical SAM additional 4Fe4S-binding domain.


ensembl_gene_id: DespoDRAFT_01089
symbol: EIM63060.1
gene_biotype: protein_coding
description:
  PFAM: Radical SAM superfamily; TIGRFAM: putative heme d1 biosynthesis radical SAM protein NirJ1; radical SAM additional 4Fe4S-binding domain.


ensembl_gene_id: DespoDRAFT_01090
symbol: EIM63061.1
gene_biotype: protein_coding
description:
  ATP-dependent protease Clp, ATPase subunit; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; TIGRFAM: endopeptidase Clp ATP-binding regulatory subunit (clpX); Belongs to the ClpX chaperone family.


ensembl_gene_id: DespoDRAFT_01093
symbol: EIM63063.1
gene_biotype: protein_coding
description:
  Protein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.


ensembl_gene_id: DespoDRAFT_01094
symbol: tpiA
gene_biotype: protein_coding
description:
  Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.


ensembl_gene_id: DespoDRAFT_01095
symbol: EIM63065.1
gene_biotype: protein_coding
description:
  PFAM: Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.


ensembl_gene_id: DespoDRAFT_01096
symbol: EIM63066.1
gene_biotype: protein_coding
description:
  PFAM: PTS system fructose IIA component; TIGRFAM: PTS system, mannose/fructose/sorbose family, IIA component.


ensembl_gene_id: DespoDRAFT_01099
symbol: EIM63069.1
gene_biotype: protein_coding
description:
  PFAM: Sigma 54 modulation protein / S30EA ribosomal protein; TIGRFAM: ribosomal subunit interface protein.


ensembl_gene_id: DespoDRAFT_01100
symbol: EIM63070.1
gene_biotype: protein_coding
description:
  RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.


ensembl_gene_id: DespoDRAFT_01104
symbol: EIM63074.1
gene_biotype: protein_coding
description:
  PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; HAD-superfamily hydrolase, subfamily IIIA.


ensembl_gene_id: DespoDRAFT_01105
symbol: kdsA
gene_biotype: protein_coding
description:
  PFAM: DAHP synthetase I family; TIGRFAM: 3-deoxy-8-phosphooctulonate synthase; Belongs to the KdsA family.


ensembl_gene_id: DespoDRAFT_01108
symbol: EIM63078.1
gene_biotype: protein_coding
description:
  PFAM: Peptidase S24-like; TIGRFAM: signal peptidase I, bacterial type; Belongs to the peptidase S26 family.


ensembl_gene_id: DespoDRAFT_01109
symbol: pyrB
gene_biotype: protein_coding
description:
  PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFAM: aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.


ensembl_gene_id: DespoDRAFT_01110
symbol: pyrC
gene_biotype: protein_coding
description:
  Dihydroorotase, multifunctional complex type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.


ensembl_gene_id: DespoDRAFT_01114
symbol: EIM63084.1
gene_biotype: protein_coding
description:
  PFAM: Prokaryotic N-terminal methylation motif; TIGRFAM: prepilin-type N-terminal cleavage/methylation domain.


ensembl_gene_id: DespoDRAFT_01132
symbol: EIM63100.1
gene_biotype: protein_coding
description:
  PFAM: Prokaryotic N-terminal methylation motif; TIGRFAM: type IV pilus modification protein PilV; prepilin-type N-terminal cleavage/methylation domain.


ensembl_gene_id: DespoDRAFT_01133
symbol: EIM63101.1
gene_biotype: protein_coding
description:
  TIGRFAM: prepilin-type N-terminal cleavage/methylation domain; overlaps another CDS with the same product name.


ensembl_gene_id: DespoDRAFT_01134
symbol: EIM63102.1
gene_biotype: protein_coding
description:
  PFAM: Prokaryotic N-terminal methylation motif; Type II transport protein GspH; TIGRFAM: prepilin-type N-terminal cleavage/methylation domain; overlaps another CDS with the same product name.


ensembl_gene_id: DespoDRAFT_01135
symbol: thiC
gene_biotype: protein_coding
description:
  Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.


ensembl_gene_id: DespoDRAFT_01137
symbol: EIM63105.1
gene_biotype: protein_coding
description:
  Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.


ensembl_gene_id: DespoDRAFT_01139
symbol: xerC
gene_biotype: protein_coding
description:
  Site-specific recombinase XerD; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.


ensembl_gene_id: DespoDRAFT_01140
symbol: hslV
gene_biotype: protein_coding
description:
  ATP-dependent protease HslVU, peptidase subunit; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.


ensembl_gene_id: DespoDRAFT_01141
symbol: hslU
gene_biotype: protein_coding
description:
  ATP-dependent protease HslVU, ATPase subunit; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.


ensembl_gene_id: DespoDRAFT_01142
symbol: argB
gene_biotype: protein_coding
description:
  Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.


ensembl_gene_id: DespoDRAFT_01143
symbol: argD
gene_biotype: protein_coding
description:
  PFAM: Aminotransferase class-III; TIGRFAM: acetylornithine and succinylornithine transaminases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.


ensembl_gene_id: DespoDRAFT_01144
symbol: EIM63112.1
gene_biotype: protein_coding
description:
  Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.


ensembl_gene_id: DespoDRAFT_01147
symbol: EIM63115.1
gene_biotype: protein_coding
description:
  PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK); TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase.


ensembl_gene_id: DespoDRAFT_01148
symbol: tal
gene_biotype: protein_coding
description:
  Fructose-6-phosphate aldolase, TalC/MipB family; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.


ensembl_gene_id: DespoDRAFT_01162
symbol: EIM63128.1
gene_biotype: protein_coding
description:
  PFAM: CagE, TrbE, VirB family, component of type IV transporter system; Type IV secretory pathway, VirB3-like protein; TIGRFAM: type IV secretion/conjugal transfer ATPase, VirB4 family.


ensembl_gene_id: DespoDRAFT_01165
symbol: EIM63131.1
gene_biotype: protein_coding
description:
  PFAM: TrbL/VirB6 plasmid conjugal transfer protein; TIGRFAM: P-type conjugative transfer protein TrbL.


ensembl_gene_id: DespoDRAFT_01170
symbol: EIM63136.1
gene_biotype: protein_coding
description:
  PFAM: Toprim domain; DNA topoisomerase; TIGRFAM: DNA topoisomerase III, bacteria and conjugative plasmid.


ensembl_gene_id: DespoDRAFT_01174
symbol: EIM63140.1
gene_biotype: protein_coding
description:
  Type IV secretory pathway, protease TraF; PFAM: Peptidase S26; TIGRFAM: conjugative transfer signal peptidase TraF.


ensembl_gene_id: DespoDRAFT_01175
symbol: EIM63141.1
gene_biotype: protein_coding
description:
  P-type conjugative transfer ATPase TrbB; PFAM: Type II/IV secretion system protein; TIGRFAM: P-type conjugative transfer ATPase TrbB.


ensembl_gene_id: DespoDRAFT_01179
symbol: EIM63145.1
gene_biotype: protein_coding
description:
  Cytotoxic translational repressor of toxin-antitoxin stability system; PFAM: Plasmid stabilisation system protein.


ensembl_gene_id: DespoDRAFT_01183
symbol: EIM63149.1
gene_biotype: protein_coding
description:
  Methylase involved in ubiquinone/menaquinone biosynthesis; PFAM: Methyltransferase domain; manually curated.


ensembl_gene_id: DespoDRAFT_01184
symbol: EIM63150.1
gene_biotype: protein_coding
description:
  DnaJ-class molecular chaperone with C-terminal Zn finger domain; PFAM: DnaJ domain; manually curated.


ensembl_gene_id: DespoDRAFT_01206
symbol: EIM63171.1
gene_biotype: protein_coding
description:
  Site-specific recombinase XerD; PFAM: Phage integrase family; Belongs to the 'phage' integrase family.


ensembl_gene_id: DespoDRAFT_01224
symbol: EIM63188.1
gene_biotype: protein_coding
description:
  PFAM: Toprim domain; Topoisomerase DNA binding C4 zinc finger; DNA topoisomerase; TIGRFAM: DNA topoisomerase III, bacteria and conjugative plasmid.


ensembl_gene_id: DespoDRAFT_01234
symbol: EIM63198.1
gene_biotype: protein_coding
description:
  Nuclease-like protein,protein kinase family protein; PFAM: Protein kinase domain; Nuclease-related domain.


ensembl_gene_id: DespoDRAFT_01244
symbol: EIM63208.1
gene_biotype: protein_coding
description:
  PFAM: Uncharacterised protein family UPF0047; TIGRFAM: secondary thiamine-phosphate synthase enzyme.


ensembl_gene_id: DespoDRAFT_01260
symbol: tyrS
gene_biotype: protein_coding
description:
  tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.


ensembl_gene_id: DespoDRAFT_01304
symbol: EIM63262.1
gene_biotype: protein_coding
description:
  PFAM: Reverse transcriptase (RNA-dependent DNA polymerase); Group II intron, maturase-specific domain; manually curated; partial gene.


ensembl_gene_id: DespoDRAFT_01309
symbol: EIM63267.1
gene_biotype: protein_coding
description:
  Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains; PFAM: Response regulator receiver domain; manually curated; partial gene.


ensembl_gene_id: DespoDRAFT_01311
symbol: EIM63269.1
gene_biotype: protein_coding
description:
  Iron-sulfur cluster repair di-iron protein; Di-iron-containing protein involved in the repair of iron- sulfur clusters; Belongs to the RIC family.


ensembl_gene_id: DespoDRAFT_01324
symbol: EIM63280.1
gene_biotype: protein_coding
description:
  PFAM: Reverse transcriptase (RNA-dependent DNA polymerase); Group II intron, maturase-specific domain.


ensembl_gene_id: DespoDRAFT_01328
symbol: EIM63282.1
gene_biotype: protein_coding
description:
  Copper/silver-translocating P-type ATPase; PFAM: E1-E2 ATPase; Heavy-metal-associated domain; haloacid dehalogenase-like hydrolase; TIGRFAM: copper-(or silver)-translocating P-type ATPase; copper ion binding protein; heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC.


ensembl_gene_id: DespoDRAFT_01338
symbol: EIM63291.1
gene_biotype: protein_coding
description:
  PFAM: NapC/NirT cytochrome c family, N-terminal region; TIGRFAM: cytochrome c nitrate reductase, small subunit.


ensembl_gene_id: DespoDRAFT_01342
symbol: EIM63295.1
gene_biotype: protein_coding
description:
  PFAM: Domain of unknown function (DUF1858); TIGRFAM: hybrid cluster protein-associated redox disulfide domain.


ensembl_gene_id: DespoDRAFT_01362
symbol: dapA
gene_biotype: protein_coding
description:
  Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).


ensembl_gene_id: DespoDRAFT_01364
symbol: EIM63313.1
gene_biotype: protein_coding
description:
  PFAM: Nitrite and sulphite reductase 4Fe-4S domain; TIGRFAM: sulfite reductase, dissimilatory-type alpha subunit.


ensembl_gene_id: DespoDRAFT_01365
symbol: EIM63314.1
gene_biotype: protein_coding
description:
  Sulfite reductase, dissimilatory-type beta subunit; PFAM: Nitrite and sulphite reductase 4Fe-4S domain; Nitrite/Sulfite reductase ferredoxin-like half domain; TIGRFAM: sulfite reductase, dissimilatory-type beta subunit.


ensembl_gene_id: DespoDRAFT_01371
symbol: EIM63319.1
gene_biotype: protein_coding
description:
  Putative membrane protein involved in D-alanine export; PFAM: MBOAT family; Belongs to the membrane-bound acyltransferase family.


ensembl_gene_id: DespoDRAFT_01377
symbol: plsY
gene_biotype: protein_coding
description:
  Putative membrane protein; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.


ensembl_gene_id: DespoDRAFT_01386
symbol: EIM63334.1
gene_biotype: protein_coding
description:
  EDD domain protein, DegV family; PFAM: DAK2 domain; Radical SAM superfamily; B12 binding domain; Uncharacterised protein, DegV family COG1307; TIGRFAM: EDD domain protein, DegV family.


ensembl_gene_id: DespoDRAFT_01389
symbol: EIM63337.1
gene_biotype: protein_coding
description:
  PFAM: Beta-ketoacyl synthase, N-terminal domain; Beta-ketoacyl synthase, C-terminal domain; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: DespoDRAFT_01404
symbol: EIM63352.1
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase; PFAM: Glycosyl transferase family 4.


ensembl_gene_id: DespoDRAFT_01406
symbol: murA
gene_biotype: protein_coding
description:
  UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.


ensembl_gene_id: DespoDRAFT_01407
symbol: EIM63355.1
gene_biotype: protein_coding
description:
  PFAM: Competence protein; Metallo-beta-lactamase superfamily; TIGRFAM: ComEC/Rec2-related protein; DNA internalization-related competence protein ComEC/Rec2.


ensembl_gene_id: DespoDRAFT_01410
symbol: EIM63358.1
gene_biotype: protein_coding
description:
  Putative integral membrane protein; PFAM: Domain of unknown function DUF140; TIGRFAM: conserved hypothetical integral membrane protein.


ensembl_gene_id: DespoDRAFT_01411
symbol: EIM63359.1
gene_biotype: protein_coding
description:
  ABC-type transport system involved in resistance to organic solvents, ATPase component; PFAM: ABC transporter.


ensembl_gene_id: DespoDRAFT_01412
symbol: EIM63360.1
gene_biotype: protein_coding
description:
  ABC-type transport system involved in resistance to organic solvents, periplasmic component; PFAM: mce related protein; TIGRFAM: virulence factor Mce family protein.


ensembl_gene_id: DespoDRAFT_01420
symbol: miaA
gene_biotype: protein_coding
description:
  tRNA isopentenyltransferase MiaA; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.


ensembl_gene_id: DespoDRAFT_01423
symbol: EIM63369.1
gene_biotype: protein_coding
description:
  ABC-type branched-chain amino acid transport system, periplasmic component; PFAM: Receptor family ligand binding region.


ensembl_gene_id: DespoDRAFT_01424
symbol: pfkA
gene_biotype: protein_coding
description:
  6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily.


ensembl_gene_id: DespoDRAFT_01425
symbol: EIM63371.1
gene_biotype: protein_coding
description:
  KpsF/GutQ family protein; PFAM: CBS domain; SIS domain; TIGRFAM: KpsF/GutQ family protein; Belongs to the SIS family. GutQ/KpsF subfamily.


ensembl_gene_id: DespoDRAFT_01428
symbol: truA
gene_biotype: protein_coding
description:
  Pseudouridylate synthase I; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.


ensembl_gene_id: DespoDRAFT_01429
symbol: EIM63375.1
gene_biotype: protein_coding
description:
  Putative quinone oxidoreductase, YhdH/YhfP family; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; TIGRFAM: putative quinone oxidoreductase, YhdH/YhfP family.


ensembl_gene_id: DespoDRAFT_01430
symbol: EIM63376.1
gene_biotype: protein_coding
description:
  Aspartate ammonia-lyase; PFAM: Fumarase C C-terminus; Lyase; Cyclic nucleotide-binding domain; TIGRFAM: aspartate ammonia-lyase.


ensembl_gene_id: DespoDRAFT_01434
symbol: EIM63379.1
gene_biotype: protein_coding
description:
  Periplasmic serine protease, Do/DeqQ family; PFAM: Trypsin; PDZ domain (Also known as DHR or GLGF); TIGRFAM: periplasmic serine protease, Do/DeqQ family; Belongs to the peptidase S1C family.


ensembl_gene_id: DespoDRAFT_01441
symbol: EIM63385.1
gene_biotype: protein_coding
description:
  C-terminal processing peptidase; PFAM: C-terminal domain of tail specific protease (DUF3340); Peptidase family S41; PDZ domain (Also known as DHR or GLGF); TIGRFAM: C-terminal peptidase (prc); Belongs to the peptidase S41A family.


ensembl_gene_id: DespoDRAFT_01442
symbol: EIM63386.1
gene_biotype: protein_coding
description:
  Ribosome biogenesis GTP-binding protein YlqF; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.


ensembl_gene_id: DespoDRAFT_01444
symbol: EIM63388.1
gene_biotype: protein_coding
description:
  PFAM: Inositol monophosphatase family; TIGRFAM: histidinol-phosphate phosphatase HisN, inositol monophosphatase family.


ensembl_gene_id: DespoDRAFT_01451
symbol: EIM63395.1
gene_biotype: protein_coding
description:
  PFAM: ABC transporter transmembrane region; ABC transporter; TIGRFAM: type I secretion system ABC transporter, PrtD family.


ensembl_gene_id: DespoDRAFT_01452
symbol: EIM63396.1
gene_biotype: protein_coding
description:
  ABC-type protease/lipase transport system, ATPase and permease component; PFAM: ABC transporter; TIGRFAM: type I secretion system ABC transporter, PrtD family.


ensembl_gene_id: DespoDRAFT_01453
symbol: EIM63397.1
gene_biotype: protein_coding
description:
  PFAM: HlyD family secretion protein; TIGRFAM: type I secretion membrane fusion protein, HlyD family.


ensembl_gene_id: DespoDRAFT_01475
symbol: EIM63414.1
gene_biotype: protein_coding
description:
  Hypothetical protein; PFAM: Putative transposase, YhgA-like; TIGRFAM: conserved hypothetical protein (putative transposase or invertase).


ensembl_gene_id: DespoDRAFT_01490
symbol: gmd
gene_biotype: protein_coding
description:
  GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose.


ensembl_gene_id: DespoDRAFT_01491
symbol: EIM63427.1
gene_biotype: protein_coding
description:
  ABC-type polysaccharide/polyol phosphate export system, permease component; PFAM: ABC-2 type transporter.


ensembl_gene_id: DespoDRAFT_01509
symbol: efp
gene_biotype: protein_coding
description:
  Translation elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.


ensembl_gene_id: DespoDRAFT_01513
symbol: EIM63449.1
gene_biotype: protein_coding
description:
  Ni,Fe-hydrogenase III large subunit; PFAM: Respiratory-chain NADH dehydrogenase, 30 Kd subunit; Respiratory-chain NADH dehydrogenase, 49 Kd subunit.


ensembl_gene_id: DespoDRAFT_01514
symbol: EIM63450.1
gene_biotype: protein_coding
description:
  Formate hydrogenlyase subunit 3/multisubunit Na+/H+ antiporter, MnhD subunit; PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains.


ensembl_gene_id: DespoDRAFT_01520
symbol: EIM63456.1
gene_biotype: protein_coding
description:
  Potassium uptake protein, TrkH family; Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA; Belongs to the TrkH potassium transport family.


ensembl_gene_id: DespoDRAFT_01522
symbol: EIM63458.1
gene_biotype: protein_coding
description:
  Di-/tricarboxylate transporter; PFAM: Sodium:sulfate symporter transmembrane region; TIGRFAM: anion transporter.


ensembl_gene_id: DespoDRAFT_01525
symbol: EIM63461.1
gene_biotype: protein_coding
description:
  Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains; PFAM: Bacterial regulatory protein, Fis family; Sigma-54 interaction domain.


ensembl_gene_id: DespoDRAFT_01535
symbol: EIM63471.1
gene_biotype: protein_coding
description:
  Penicillin-binding protein 2; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain; TIGRFAM: penicillin-binding protein 2.


ensembl_gene_id: DespoDRAFT_01536
symbol: mrdB
gene_biotype: protein_coding
description:
  Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.


ensembl_gene_id: DespoDRAFT_01538
symbol: atpF-3
gene_biotype: protein_coding
description:
  ATP synthase, F0 subunit b; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family.


ensembl_gene_id: DespoDRAFT_01539
symbol: atpH
gene_biotype: protein_coding
description:
  ATP synthase, F1 delta subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.


ensembl_gene_id: DespoDRAFT_01541
symbol: atpG
gene_biotype: protein_coding
description:
  ATP synthase, F1 gamma subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.


ensembl_gene_id: DespoDRAFT_01543
symbol: atpC-2
gene_biotype: protein_coding
description:
  ATP synthase, F1 epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane.


ensembl_gene_id: DespoDRAFT_01544
symbol: EIM63480.1
gene_biotype: protein_coding
description:
  N-acetylglucosamine-1-phosphate uridylyltransferase/acetyltransferase; PFAM: Nucleotidyl transferase; TIGRFAM: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase.


ensembl_gene_id: DespoDRAFT_01563
symbol: EIM63493.1
gene_biotype: protein_coding
description:
  Ni,Fe-hydrogenase I large subunit; PFAM: Nickel-dependent hydrogenase; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.


ensembl_gene_id: DespoDRAFT_01564
symbol: EIM63494.1
gene_biotype: protein_coding
description:
  Hydrogenase (NiFe) small subunit HydA; PFAM: NADH ubiquinone oxidoreductase, 20 Kd subunit; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence; hydrogenase (NiFe) small subunit (hydA).


ensembl_gene_id: DespoDRAFT_01567
symbol: EIM63497.1
gene_biotype: protein_coding
description:
  ABC-type transport system involved in Fe-S cluster assembly, permease component; PFAM: Uncharacterized protein family (UPF0051).


ensembl_gene_id: DespoDRAFT_01568
symbol: EIM63498.1
gene_biotype: protein_coding
description:
  ABC-type transport system involved in Fe-S cluster assembly, ATPase component; PFAM: ABC transporter.


ensembl_gene_id: DespoDRAFT_01570
symbol: EIM63500.1
gene_biotype: protein_coding
description:
  ABC-type dipeptide/oligopeptide/nickel transport system, permease component; PFAM: Binding-protein-dependent transport system inner membrane component.


ensembl_gene_id: DespoDRAFT_01574
symbol: EIM63504.1
gene_biotype: protein_coding
description:
  Outer membrane receptor protein; PFAM: TonB dependent receptor; TonB-dependent Receptor Plug Domain.


ensembl_gene_id: DespoDRAFT_01576
symbol: EIM63506.1
gene_biotype: protein_coding
description:
  TonB family protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.


ensembl_gene_id: DespoDRAFT_01578
symbol: EIM63508.1
gene_biotype: protein_coding
description:
  Biopolymer transport protein; PFAM: MotA/TolQ/ExbB proton channel family; overlaps another CDS with the same product name.


ensembl_gene_id: DespoDRAFT_01581
symbol: EIM63511.1
gene_biotype: protein_coding
description:
  NhaP-type Na+(K+)/H+ antiporter; PFAM: TrkA-N domain; Sodium/hydrogen exchanger family; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.


ensembl_gene_id: DespoDRAFT_01582
symbol: EIM63512.1
gene_biotype: protein_coding
description:
  Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.


ensembl_gene_id: DespoDRAFT_01584
symbol: EIM63514.1
gene_biotype: protein_coding
description:
  PFAM: Pyridoxal-dependent decarboxylase, C-terminal sheet domain; Pyridoxal-dependent decarboxylase, pyridoxal binding domain.


ensembl_gene_id: DespoDRAFT_01594
symbol: EIM63524.1
gene_biotype: protein_coding
description:
  FAD/FMN-dependent dehydrogenase; PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain; TIGRFAM: glycolate oxidase, subunit GlcD.


ensembl_gene_id: DespoDRAFT_01596
symbol: EIM63525.1
gene_biotype: protein_coding
description:
  PFAM: Reverse transcriptase (RNA-dependent DNA polymerase); Group II intron, maturase-specific domain; manually curated.


ensembl_gene_id: DespoDRAFT_01601
symbol: EIM63529.1
gene_biotype: protein_coding
description:
  PFAM: Surface antigen variable number repeat; Surface antigen; TIGRFAM: outer membrane protein assembly complex, YaeT protein.


ensembl_gene_id: DespoDRAFT_01603
symbol: EIM63531.1
gene_biotype: protein_coding
description:
  Glutamyl- or glutaminyl-tRNA synthetase; PFAM: tRNA synthetases class I (E and Q), catalytic domain; Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: DespoDRAFT_01605
symbol: topA
gene_biotype: protein_coding
description:
  DNA topoisomerase I, bacterial; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removi [...]


ensembl_gene_id: DespoDRAFT_01607
symbol: cpoB
gene_biotype: protein_coding
description:
  Tol-pal system protein YbgF; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family.


ensembl_gene_id: DespoDRAFT_01608
symbol: secF
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.


ensembl_gene_id: DespoDRAFT_01609
symbol: secD
gene_biotype: protein_coding
description:
  Protein-export membrane protein, SecD/SecF family; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.


ensembl_gene_id: DespoDRAFT_01610
symbol: yajC
gene_biotype: protein_coding
description:
  Preprotein translocase, YajC subunit; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.


ensembl_gene_id: DespoDRAFT_01612
symbol: EIM63540.1
gene_biotype: protein_coding
description:
  Ribonuclease, Rne/Rng family; PFAM: Ribonuclease E/G family; S1 RNA binding domain; TIGRFAM: ribonuclease, Rne/Rng family.


ensembl_gene_id: DespoDRAFT_01613
symbol: EIM63541.1
gene_biotype: protein_coding
description:
  Putative soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein; Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella. In the N-terminal section; belongs to the bac [...]


ensembl_gene_id: DespoDRAFT_01614
symbol: parC
gene_biotype: protein_coding
description:
  DNA topoisomerase IV, A subunit, proteobacterial; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.


ensembl_gene_id: DespoDRAFT_01615
symbol: parE
gene_biotype: protein_coding
description:
  DNA topoisomerase IV, B subunit, proteobacterial; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily.


ensembl_gene_id: DespoDRAFT_01617
symbol: EIM63545.1
gene_biotype: protein_coding
description:
  TIGR00730 family protein; PFAM: Possible lysine decarboxylase; TIGRFAM: TIGR00725 family protein; TIGR00730 family protein; Belongs to the LOG family.


ensembl_gene_id: DespoDRAFT_01619
symbol: EIM63547.1
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).


ensembl_gene_id: DespoDRAFT_01621
symbol: smpB
gene_biotype: protein_coding
description:
  SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]


ensembl_gene_id: DespoDRAFT_01631
symbol: EIM63555.1
gene_biotype: protein_coding
description:
  Glycosyltransferase; PFAM: Glycosyl transferases group 1; TIGRFAM: sugar transferase, PEP-CTERM/EpsH1 system associated.


ensembl_gene_id: DespoDRAFT_01634
symbol: EIM63558.1
gene_biotype: protein_coding
description:
  Addiction module toxin, RelE/StbE family; PFAM: Plasmid stabilisation system protein; TIGRFAM: addiction module toxin component, YafQ family; addiction module toxin, RelE/StbE family.


ensembl_gene_id: DespoDRAFT_01645
symbol: EIM63569.1
gene_biotype: protein_coding
description:
  PFAM: Asparagine synthase; TIGRFAM: asparagine synthase (glutamine-hydrolyzing); exosortase A system-associated amidotransferase 1.


ensembl_gene_id: DespoDRAFT_01653
symbol: EIM63577.1
gene_biotype: protein_coding
description:
  Membrane protein involved in the export of O-antigen and teichoic acid; PFAM: Polysaccharide biosynthesis protein.


ensembl_gene_id: DespoDRAFT_01661
symbol: EIM63585.1
gene_biotype: protein_coding
description:
  PFAM: Glycosyl transferases group 1; Glycosyl transferase family 2; TIGRFAM: PEP-CTERM/exosortase A-associated glycosyltransferase, Daro_2409 family.


ensembl_gene_id: DespoDRAFT_01663
symbol: EIM63587.1
gene_biotype: protein_coding
description:
  Putative methicillin resistance protein; PFAM: FemAB family; TIGRFAM: FemAB-related protein, PEP-CTERM system-associated.


ensembl_gene_id: DespoDRAFT_01677
symbol: EIM63596.1
gene_biotype: protein_coding
description:
  PFAM: Nucleotidyltransferase substrate binding protein like; TIGRFAM: nucleotidyltransferase substrate binding protein, HI0074 family.


ensembl_gene_id: DespoDRAFT_01682
symbol: EIM63601.1
gene_biotype: protein_coding
description:
  PFAM: UDP-N-acetylglucosamine 2-epimerase; TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family.


ensembl_gene_id: DespoDRAFT_01683
symbol: EIM63602.1
gene_biotype: protein_coding
description:
  Nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; TIGRFAM: nucleotide sugar dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.


ensembl_gene_id: DespoDRAFT_01684
symbol: EIM63603.1
gene_biotype: protein_coding
description:
  PFAM: Domain of unknown function (DUF3473); Polysaccharide deacetylase; TIGRFAM: polysaccharide deacetylase family protein, PEP-CTERM locus subfamily.


ensembl_gene_id: DespoDRAFT_01685
symbol: EIM63604.1
gene_biotype: protein_coding
description:
  PFAM: Transmembrane exosortase (Exosortase_EpsH); TIGRFAM: exosortase/archaeosortase family protein; exosortase.


ensembl_gene_id: DespoDRAFT_01689
symbol: EIM63608.1
gene_biotype: protein_coding
description:
  PFAM: Bacterial sugar transferase; TIGRFAM: sugar transferase, PEP-CTERM system associated; exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase.


ensembl_gene_id: DespoDRAFT_01690
symbol: EIM63609.1
gene_biotype: protein_coding
description:
  Capsular exopolysaccharide biosynthesis protein; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain; TIGRFAM: exopolysaccharide/PEPCTERM locus tyrosine autokinase; capsular exopolysaccharide family.


ensembl_gene_id: DespoDRAFT_01691
symbol: EIM63610.1
gene_biotype: protein_coding
description:
  Uncharacterized protein involved in exopolysaccharide biosynthesis; PFAM: Chain length determinant protein; TIGRFAM: polysaccharide chain length determinant protein, PEP-CTERM locus subfamily.


ensembl_gene_id: DespoDRAFT_01694
symbol: EIM63613.1
gene_biotype: protein_coding
description:
  Type II secretory pathway, component ExeA (predicted ATPase); PFAM: ATPase family associated with various cellular activities (AAA); OmpA family.


ensembl_gene_id: DespoDRAFT_01707
symbol: EIM63626.1
gene_biotype: protein_coding
description:
  UDP-glucose-4-epimerase; PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: UDP-glucose-4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family.


ensembl_gene_id: DespoDRAFT_01711
symbol: EIM63630.1
gene_biotype: protein_coding
description:
  Flagellar basal body-associated protein FliL; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.


ensembl_gene_id: DespoDRAFT_01712
symbol: EIM63631.1
gene_biotype: protein_coding
description:
  PFAM: Thiamin pyrophosphokinase, vitamin B1 binding domain; Thiamin pyrophosphokinase, catalytic domain; TIGRFAM: thiamine pyrophosphokinase.


ensembl_gene_id: DespoDRAFT_01715
symbol: EIM63634.1
gene_biotype: protein_coding
description:
  3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.


ensembl_gene_id: DespoDRAFT_01716
symbol: lpxK
gene_biotype: protein_coding
description:
  Tetraacyldisaccharide 4''-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).


ensembl_gene_id: DespoDRAFT_01718
symbol: EIM63637.1
gene_biotype: protein_coding
description:
  Lipopolysaccharide heptosyltransferase II; PFAM: Glycosyltransferase family 9 (heptosyltransferase); TIGRFAM: lipopolysaccharide heptosyltransferase II.


ensembl_gene_id: DespoDRAFT_01719
symbol: EIM63638.1
gene_biotype: protein_coding
description:
  PFAM: Glycosyltransferase family 9 (heptosyltransferase); TIGRFAM: lipopolysaccharide heptosyltransferase I; lipopolysaccharide heptosyltransferase II.


ensembl_gene_id: DespoDRAFT_01728
symbol: kdsB
gene_biotype: protein_coding
description:
  3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.


ensembl_gene_id: DespoDRAFT_01730
symbol: EIM63649.1
gene_biotype: protein_coding
description:
  Putative PLP-dependent enzyme possibly involved in cell wall biogenesis; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase family; Belongs to the DegT/DnrJ/EryC1 family.


ensembl_gene_id: DespoDRAFT_01732
symbol: EIM63651.1
gene_biotype: protein_coding
description:
  Putative oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.


ensembl_gene_id: DespoDRAFT_01733
symbol: EIM63652.1
gene_biotype: protein_coding
description:
  PFAM: Elongation factor Tu domain 2; Elongation factor SelB, winged helix; Elongation factor Tu GTP binding domain; TIGRFAM: selenocysteine-specific elongation factor SelB; small GTP-binding protein domain; translation elongation factor TU.


ensembl_gene_id: DespoDRAFT_01742
symbol: serC
gene_biotype: protein_coding
description:
  Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.


ensembl_gene_id: DespoDRAFT_01743
symbol: EIM63660.1
gene_biotype: protein_coding
description:
  PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; ACT domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; TIGRFAM: D-3-phosphoglycerate dehydrogenase.


ensembl_gene_id: DespoDRAFT_01748
symbol: EIM63665.1
gene_biotype: protein_coding
description:
  N-carbamoylputrescine amidase; PFAM: Carbon-nitrogen hydrolase; TIGRFAM: N-carbamoylputrescine amidase.


ensembl_gene_id: DespoDRAFT_01749
symbol: EIM63666.1
gene_biotype: protein_coding
description:
  Peptidylarginine deiminase-like enzyme; PFAM: Porphyromonas-type peptidyl-arginine deiminase; TIGRFAM: agmatine deiminase; Belongs to the agmatine deiminase family.


ensembl_gene_id: DespoDRAFT_01750
symbol: EIM63667.1
gene_biotype: protein_coding
description:
  Spermidine/putrescine-binding periplasmic protein; Required for the activity of the bacterial periplasmic transport system of putrescine; Belongs to the bacterial solute-binding protein PotD/PotF family.


ensembl_gene_id: DespoDRAFT_01751
symbol: EIM63668.1
gene_biotype: protein_coding
description:
  ABC-type spermidine/putrescine transport system, permease component II; PFAM: Binding-protein-dependent transport system inner membrane component.


ensembl_gene_id: DespoDRAFT_01752
symbol: EIM63669.1
gene_biotype: protein_coding
description:
  ABC-type spermidine/putrescine transport system, permease component I; PFAM: Binding-protein-dependent transport system inner membrane component.


ensembl_gene_id: DespoDRAFT_01753
symbol: EIM63670.1
gene_biotype: protein_coding
description:
  ABC-type spermidine/putrescine transport system, ATPase component; PFAM: ABC transporter; TOBE domain.


ensembl_gene_id: DespoDRAFT_01757
symbol: EIM63674.1
gene_biotype: protein_coding
description:
  PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; Phosphoglucomutase/phosphomannomutase, C-terminal domain; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I; TIGRFAM: phosphoglucomutase, alpha-D-glucose phosphate-specific.


ensembl_gene_id: DespoDRAFT_01759
symbol: EIM63676.1
gene_biotype: protein_coding
description:
  Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.


ensembl_gene_id: DespoDRAFT_01770
symbol: EIM63686.1
gene_biotype: protein_coding
description:
  ABC-type Co2+ transport system, permease component; PFAM: Cobalt uptake substrate-specific transmembrane region; TIGRFAM: cobalamin biosynthesis protein CbiM.


ensembl_gene_id: DespoDRAFT_01771
symbol: EIM63687.1
gene_biotype: protein_coding
description:
  ABC-type Co2+ transport system, periplasmic component; PFAM: Nickel uptake substrate-specific transmembrane region.


ensembl_gene_id: DespoDRAFT_01784
symbol: pdxA
gene_biotype: protein_coding
description:
  4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).


ensembl_gene_id: DespoDRAFT_01785
symbol: dnaA
gene_biotype: protein_coding
description:
  Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.


ensembl_gene_id: DespoDRAFT_01787
symbol: hflX
gene_biotype: protein_coding
description:
  GTP-binding protein HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.


ensembl_gene_id: DespoDRAFT_01788
symbol: EIM63704.1
gene_biotype: protein_coding
description:
  Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily.


ensembl_gene_id: DespoDRAFT_01791
symbol: rpsR
gene_biotype: protein_coding
description:
  Ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.


ensembl_gene_id: DespoDRAFT_01802
symbol: leuS
gene_biotype: protein_coding
description:
  PFAM: tRNA synthetases class I (I, L, M and V); Anticodon-binding domain; TIGRFAM: leucyl-tRNA synthetase, eubacterial and mitochondrial family; Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: DespoDRAFT_01815
symbol: trpD
gene_biotype: protein_coding
description:
  Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).


ensembl_gene_id: DespoDRAFT_01816
symbol: EIM63731.1
gene_biotype: protein_coding
description:
  PFAM: Glutamine amidotransferase class-I; TIGRFAM: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase.


ensembl_gene_id: DespoDRAFT_01821
symbol: EIM63736.1
gene_biotype: protein_coding
description:
  PFAM: Probable molybdopterin binding domain; Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA N-terminal domain; competence/damage-inducible protein CinA C-terminal domain; molybdenum cofactor synthesis domain.


ensembl_gene_id: DespoDRAFT_01822
symbol: EIM63737.1
gene_biotype: protein_coding
description:
  Outer membrane protein/peptidoglycan-associated (lipo)protein; PFAM: Rickettsia 17 kDa surface antigen; OmpA family.


ensembl_gene_id: DespoDRAFT_01824
symbol: EIM63739.1
gene_biotype: protein_coding
description:
  PFAM: tRNA (Uracil-5-)-methyltransferase; TIGRFAM: 23S rRNA (uracil-5-)-methyltransferase RumA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.


ensembl_gene_id: DespoDRAFT_01827
symbol: ribB
gene_biotype: protein_coding
description:
  3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.


ensembl_gene_id: DespoDRAFT_01835
symbol: EIM63750.1
gene_biotype: protein_coding
description:
  P-type ATPase, translocating; PFAM: E1-E2 ATPase; Cation transporting ATPase, C-terminus; Cation transporter/ATPase, N-terminus; haloacid dehalogenase-like hydrolase; TIGRFAM: plasma-membrane calcium-translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC.


ensembl_gene_id: DespoDRAFT_01840
symbol: EIM63753.1
gene_biotype: protein_coding
description:
  Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL-like protein; PFAM: 2Fe-2S iron-sulfur cluster binding domain; Molybdopterin-binding domain of aldehyde dehydrogenase; Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; [2Fe-2S] binding domain.


ensembl_gene_id: DespoDRAFT_01842
symbol: xerD
gene_biotype: protein_coding
description:
  Tyrosine recombinase XerD; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.


ensembl_gene_id: DespoDRAFT_01843
symbol: mfd
gene_biotype: protein_coding
description:
  Transcription-repair coupling factor Mfd; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.


ensembl_gene_id: DespoDRAFT_01849
symbol: zupT
gene_biotype: protein_coding
description:
  Putative divalent heavy-metal cations transporter; Mediates zinc uptake. May also transport other divalent cations; Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.


ensembl_gene_id: DespoDRAFT_01850
symbol: EIM63760.1
gene_biotype: protein_coding
description:
  Putative dithiol-disulfide isomerase involved in polyketide biosynthesis; PFAM: DSBA-like thioredoxin domain; Contains selenocysteine; manually curated.


ensembl_gene_id: DespoDRAFT_01853
symbol: ubiE
gene_biotype: protein_coding
description:
  Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2).


ensembl_gene_id: DespoDRAFT_01854
symbol: dnaJ
gene_biotype: protein_coding
description:
  Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]


ensembl_gene_id: DespoDRAFT_01868
symbol: EIM63778.1
gene_biotype: protein_coding
description:
  DNA-binding protein, excisionase family; PFAM: Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; TIGRFAM: DNA binding domain, excisionase family.


ensembl_gene_id: DespoDRAFT_01880
symbol: EIM63790.1
gene_biotype: protein_coding
description:
  Putative signal-transduction protein containing cAMP-binding and CBS domains; PFAM: Putative nucleotidyltransferase substrate binding domain; CBS domain; Cyclic nucleotide-binding domain; Putative nucleotidyltransferase DUF294.


ensembl_gene_id: DespoDRAFT_01906
symbol: EIM63812.1
gene_biotype: protein_coding
description:
  Dinucleotide-utilizing enzyme possibly involved in molybdopterin or thiamin biosynthesis; PFAM: ThiF family.


ensembl_gene_id: DespoDRAFT_01916
symbol: EIM63822.1
gene_biotype: protein_coding
description:
  Chemotaxis protein histidine kinase-like protein; PFAM: CheW-like domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Signal transducing histidine kinase, homodimeric domain.


ensembl_gene_id: DespoDRAFT_01919
symbol: EIM63825.1
gene_biotype: protein_coding
description:
  D-heptose-1-phosphate adenylyltransferase; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.


ensembl_gene_id: DespoDRAFT_01920
symbol: EIM63826.1
gene_biotype: protein_coding
description:
  Uncharacterized protein, YfiH family; PFAM: Multi-copper polyphenol oxidoreductase laccase; TIGRFAM: uncharacterized protein, YfiH family; Belongs to the multicopper oxidase YfiH/RL5 family.


ensembl_gene_id: DespoDRAFT_01924
symbol: atpB-2
gene_biotype: protein_coding
description:
  F0F1-type ATP synthase, alpha subunit; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family.


ensembl_gene_id: DespoDRAFT_01928
symbol: EIM63834.1
gene_biotype: protein_coding
description:
  HAMP domain-containing protein,histidine kinase,GAF domain-containing protein; PFAM: HAMP domain; GAF domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.


ensembl_gene_id: DespoDRAFT_01932
symbol: EIM63838.1
gene_biotype: protein_coding
description:
  enoyl-CoA hydratase/carnithine racemase; PFAM: Enoyl-CoA hydratase/isomerase family; Belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: DespoDRAFT_01934
symbol: mutS
gene_biotype: protein_coding
description:
  DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.


ensembl_gene_id: DespoDRAFT_01939
symbol: purU
gene_biotype: protein_coding
description:
  Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).


ensembl_gene_id: DespoDRAFT_01943
symbol: EIM63849.1
gene_biotype: protein_coding
description:
  PFAM: Biotin/lipoate A/B protein ligase family; TIGRFAM: birA, biotin-[acetyl-CoA-carboxylase] ligase region.


ensembl_gene_id: DespoDRAFT_01944
symbol: EIM63850.1
gene_biotype: protein_coding
description:
  Pyruvate carboxylase; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; Biotin carboxylase C-terminal domain; HMGL-like; Carbamoyl-phosphate synthase L chain, N-terminal domain; Biotin-requiring enzyme; Conserved carboxylase domain; TIGRFAM: pyruvate carboxylase.


ensembl_gene_id: DespoDRAFT_01952
symbol: recD2-2
gene_biotype: protein_coding
description:
  ATP-dependent exoDNAse (exonuclease V), alpha subunit/helicase superfamily I member; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily.


ensembl_gene_id: DespoDRAFT_01957
symbol: EIM63862.1
gene_biotype: protein_coding
description:
  Chemotaxis protein histidine kinase-like protein; PFAM: CheW-like domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Signal transducing histidine kinase, homodimeric domain; Hpt domain.


ensembl_gene_id: DespoDRAFT_01959
symbol: EIM63864.1
gene_biotype: protein_coding
description:
  Methylase of chemotaxis methyl-accepting protein; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.


ensembl_gene_id: DespoDRAFT_01960
symbol: cheB
gene_biotype: protein_coding
description:
  Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.


ensembl_gene_id: DespoDRAFT_01962
symbol: EIM63867.1
gene_biotype: protein_coding
description:
  PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain.


ensembl_gene_id: DespoDRAFT_01964
symbol: EIM63869.1
gene_biotype: protein_coding
description:
  Outer membrane receptor for ferrienterochelin and colicins; PFAM: TonB-dependent Receptor Plug Domain; TonB dependent receptor.


ensembl_gene_id: DespoDRAFT_01980
symbol: EIM63883.1
gene_biotype: protein_coding
description:
  PFAM: Cation efflux family; Methylamine utilisation protein MauE; TIGRFAM: cation diffusion facilitator family transporter.


ensembl_gene_id: DespoDRAFT_01991
symbol: mltG
gene_biotype: protein_coding
description:
  Hypothetical protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.


ensembl_gene_id: DespoDRAFT_01992
symbol: rnfB
gene_biotype: protein_coding
description:
  NADPH-dependent glutamate synthase beta chain-like oxidoreductase; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.


ensembl_gene_id: DespoDRAFT_01993
symbol: rnfA
gene_biotype: protein_coding
description:
  Electron transport complex, RnfABCDGE type, A subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.


ensembl_gene_id: DespoDRAFT_01994
symbol: rnfE
gene_biotype: protein_coding
description:
  Electron transport complex, RnfABCDGE type, E subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.


ensembl_gene_id: DespoDRAFT_01995
symbol: rnfG
gene_biotype: protein_coding
description:
  Electron transport complex, RnfABCDGE type, G subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the RnfG family.


ensembl_gene_id: DespoDRAFT_01996
symbol: EIM63896.1
gene_biotype: protein_coding
description:
  Putative NADH:ubiquinone oxidoreductase, subunit RnfD; PFAM: NQR2, RnfD, RnfE family; TIGRFAM: electron transport complex, RnfABCDGE type, D subunit.


ensembl_gene_id: DespoDRAFT_02008
symbol: EIM63907.1
gene_biotype: protein_coding
description:
  Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.


ensembl_gene_id: DespoDRAFT_02009
symbol: trmJ
gene_biotype: protein_coding
description:
  RNA methyltransferase, TrmH family, group 1; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.


ensembl_gene_id: DespoDRAFT_02012
symbol: EIM63911.1
gene_biotype: protein_coding
description:
  Putative nucleoside-diphosphate sugar epimerase; PFAM: Protein of unknown function (DUF2867); NmrA-like family.


ensembl_gene_id: DespoDRAFT_02014
symbol: rnfC
gene_biotype: protein_coding
description:
  Electron transport complex, RnfABCDGE type, C subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.


ensembl_gene_id: DespoDRAFT_02015
symbol: rnfD
gene_biotype: protein_coding
description:
  Electron transport complex, RnfABCDGE type, D subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the NqrB/RnfD family.


ensembl_gene_id: DespoDRAFT_02016
symbol: rnfG-2
gene_biotype: protein_coding
description:
  Putative NADH:ubiquinone oxidoreductase, subunit RnfG; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the RnfG family.


ensembl_gene_id: DespoDRAFT_02017
symbol: EIM63916.1
gene_biotype: protein_coding
description:
  Putative NADH:ubiquinone oxidoreductase, subunit RnfE; PFAM: Rnf-Nqr subunit, membrane protein; Belongs to the NqrDE/RnfAE family.


ensembl_gene_id: DespoDRAFT_02019
symbol: rnfB-2
gene_biotype: protein_coding
description:
  Electron transport complex, RnfABCDGE type, B subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.


ensembl_gene_id: DespoDRAFT_02020
symbol: EIM63919.1
gene_biotype: protein_coding
description:
  TIGR00730 family protein; PFAM: Possible lysine decarboxylase; TIGRFAM: TIGR00730 family protein; Belongs to the LOG family.


ensembl_gene_id: DespoDRAFT_02024
symbol: EIM63923.1
gene_biotype: protein_coding
description:
  Lactoylglutathione lyase-like lyase; PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily.


ensembl_gene_id: DespoDRAFT_02031
symbol: EIM63930.1
gene_biotype: protein_coding
description:
  Uncharacterized protein involved in formate dehydrogenase formation; Necessary for formate dehydrogenase activity. Belongs to the FdhE family.


ensembl_gene_id: DespoDRAFT_02032
symbol: murJ
gene_biotype: protein_coding
description:
  Integral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.


ensembl_gene_id: DespoDRAFT_02035
symbol: EIM63934.1
gene_biotype: protein_coding
description:
  Methylase involved in ubiquinone/menaquinone biosynthesis; PFAM: Bacterial regulatory protein, arsR family; Methyltransferase domain.


ensembl_gene_id: DespoDRAFT_02036
symbol: EIM63935.1
gene_biotype: protein_coding
description:
  PFAM: Nucleotidyl transferase; Mannose-6-phosphate isomerase; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Belongs to the mannose-6-phosphate isomerase type 2 family.


ensembl_gene_id: DespoDRAFT_02037
symbol: EIM63936.1
gene_biotype: protein_coding
description:
  Putative transcriptional regulator; PFAM: Uncharacterized ACR, COG1678; Belongs to the UPF0301 (AlgH) family.


ensembl_gene_id: DespoDRAFT_02049
symbol: EIM63946.1
gene_biotype: protein_coding
description:
  DNA segregation ATPase, FtsK/SpoIIIE family; PFAM: Ftsk gamma domain; FtsK/SpoIIIE family; Belongs to the FtsK/SpoIIIE/SftA family.


ensembl_gene_id: DespoDRAFT_02052
symbol: purD
gene_biotype: protein_coding
description:
  Phosphoribosylamine--glycine ligase/phosphoribosylaminoimidazole carboxylase, PurE protein; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR); Belongs to the GARS family.


ensembl_gene_id: DespoDRAFT_02053
symbol: ddl
gene_biotype: protein_coding
description:
  D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.


ensembl_gene_id: DespoDRAFT_02055
symbol: fusA
gene_biotype: protein_coding
description:
  Translation elongation factor EF-G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF- [...]


ensembl_gene_id: DespoDRAFT_02058
symbol: EIM63955.1
gene_biotype: protein_coding
description:
  PFAM: Branched-chain amino acid transport system / permease component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: DespoDRAFT_02061
symbol: EIM63957.1
gene_biotype: protein_coding
description:
  ABC-type proline/glycine betaine transport system, periplasmic component; PFAM: Substrate binding domain of ABC-type glycine betaine transport system.


ensembl_gene_id: DespoDRAFT_02062
symbol: EIM63958.1
gene_biotype: protein_coding
description:
  ABC-type proline/glycine betaine transport system, permease component; PFAM: Binding-protein-dependent transport system inner membrane component.


ensembl_gene_id: DespoDRAFT_02067
symbol: EIM63963.1
gene_biotype: protein_coding
description:
  PFAM: Rdx family; TIGRFAM: selT/selW/selH selenoprotein domain; Contains selenocysteine; manually curated.


ensembl_gene_id: DespoDRAFT_02068
symbol: EIM63964.1
gene_biotype: protein_coding
description:
  Signal transduction histidine kinase regulating C4-dicarboxylate transport system; PFAM: Cache domain; Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.


ensembl_gene_id: DespoDRAFT_02070
symbol: EIM63966.1
gene_biotype: protein_coding
description:
  Thiosulfate reductase cytochrome B subunit (membrane anchoring protein); PFAM: Cytochrome b(N-terminal)/b6/petB.


ensembl_gene_id: DespoDRAFT_02071
symbol: EIM63967.1
gene_biotype: protein_coding
description:
  Carboxynorspermidine decarboxylase; Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine; Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.


ensembl_gene_id: DespoDRAFT_02076
symbol: EIM63971.1
gene_biotype: protein_coding
description:
  NAD(P)H-nitrite reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Rhodanese-like domain.


ensembl_gene_id: DespoDRAFT_02084
symbol: tmk
gene_biotype: protein_coding
description:
  Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.


ensembl_gene_id: DespoDRAFT_02087
symbol: EIM63980.1
gene_biotype: protein_coding
description:
  NADPH-dependent glutamate synthase, homotetrameric; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: glutamate synthase (NADPH), homotetrameric.


ensembl_gene_id: DespoDRAFT_02088
symbol: EIM63981.1
gene_biotype: protein_coding
description:
  2-polyprenylphenol hydroxylase-like oxidoreductase; PFAM: Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B; Oxidoreductase NAD-binding domain.


ensembl_gene_id: DespoDRAFT_02094
symbol: EIM63987.1
gene_biotype: protein_coding
description:
  PFAM: E1-E2 ATPase; Heavy-metal-associated domain; haloacid dehalogenase-like hydrolase; TIGRFAM: copper-(or silver)-translocating P-type ATPase; copper ion binding protein; heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase.


ensembl_gene_id: DespoDRAFT_02098
symbol: EIM63991.1
gene_biotype: protein_coding
description:
  ADP-ribosyl-(dinitrogen reductase) hydrolase; PFAM: ADP-ribosylglycohydrolase; TIGRFAM: ADP-ribosyl-[dinitrogen reductase] hydrolase.


ensembl_gene_id: DespoDRAFT_02099
symbol: EIM63992.1
gene_biotype: protein_coding
description:
  2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase; PFAM: Fumarylacetoacetate (FAA) hydrolase family.


ensembl_gene_id: DespoDRAFT_02110
symbol: EIM63999.1
gene_biotype: protein_coding
description:
  Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase component; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; SNARE associated Golgi protein; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.


ensembl_gene_id: DespoDRAFT_02114
symbol: EIM64003.1
gene_biotype: protein_coding
description:
  PFAM: FabA-like domain; Beta-ketoacyl synthase, N-terminal domain; Beta-ketoacyl synthase, C-terminal domain; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: DespoDRAFT_02115
symbol: EIM64004.1
gene_biotype: protein_coding
description:
  PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III.


ensembl_gene_id: DespoDRAFT_02123
symbol: EIM64012.1
gene_biotype: protein_coding
description:
  PFAM: Ribulose-phosphate 3 epimerase family; TIGRFAM: ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.


ensembl_gene_id: DespoDRAFT_02124
symbol: EIM64013.1
gene_biotype: protein_coding
description:
  Ribosomal RNA small subunit methyltransferase RsmB; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.


ensembl_gene_id: DespoDRAFT_02125
symbol: fmt
gene_biotype: protein_coding
description:
  methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.


ensembl_gene_id: DespoDRAFT_02126
symbol: def
gene_biotype: protein_coding
description:
  Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.


ensembl_gene_id: DespoDRAFT_02127
symbol: EIM64016.1
gene_biotype: protein_coding
description:
  PFAM: Riboflavin kinase; FAD synthetase; TIGRFAM: riboflavin kinase/FMN adenylyltransferase; Belongs to the ribF family.


ensembl_gene_id: DespoDRAFT_02129
symbol: EIM64017.1
gene_biotype: protein_coding
description:
  MiaB-like tRNA modifying enzyme; PFAM: Radical SAM superfamily; Uncharacterized protein family UPF0004; TIGRFAM: MiaB-like tRNA modifying enzyme; radical SAM methylthiotransferase, MiaB/RimO family.


ensembl_gene_id: DespoDRAFT_02130
symbol: mnmA
gene_biotype: protein_coding
description:
  tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.


ensembl_gene_id: DespoDRAFT_02132
symbol: EIM64020.1
gene_biotype: protein_coding
description:
  PAS domain S-box; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box.


ensembl_gene_id: DespoDRAFT_02134
symbol: EIM64021.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.


ensembl_gene_id: DespoDRAFT_02139
symbol: EIM64025.1
gene_biotype: protein_coding
description:
  Pyruvate, phosphate dikinase; PFAM: PEP-utilising enzyme, mobile domain; PEP-utilising enzyme, TIM barrel domain; Pyruvate phosphate dikinase, PEP/pyruvate binding domain; TIGRFAM: pyruvate, phosphate dikinase; Belongs to the PEP-utilizing enzyme family.


ensembl_gene_id: DespoDRAFT_02142
symbol: EIM64028.1
gene_biotype: protein_coding
description:
  Type IV-A pilus assembly ATPase PilB; PFAM: GSPII_E N-terminal domain; Type II/IV secretion system protein; Cyclic nucleotide-binding domain; TIGRFAM: type IV-A pilus assembly ATPase PilB.


ensembl_gene_id: DespoDRAFT_02144
symbol: EIM64030.1
gene_biotype: protein_coding
description:
  PFAM: GAF domain; GGDEF domain; HDOD domain; TIGRFAM: diguanylate cyclase (GGDEF) domain; uncharacterized domain HDIG.


ensembl_gene_id: DespoDRAFT_02153
symbol: EIM64038.1
gene_biotype: protein_coding
description:
  Superfamily II RNA helicase; PFAM: Helicase conserved C-terminal domain; DSHCT (NUC185) domain; DEAD/DEAH box helicase.


ensembl_gene_id: DespoDRAFT_02154
symbol: menA
gene_biotype: protein_coding
description:
  1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily.


ensembl_gene_id: DespoDRAFT_02155
symbol: EIM64040.1
gene_biotype: protein_coding
description:
  Adenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.


ensembl_gene_id: DespoDRAFT_02157
symbol: queH
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).


ensembl_gene_id: DespoDRAFT_02158
symbol: EIM64043.1
gene_biotype: protein_coding
description:
  Pyridoxal phosphate enzyme, YggS family; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.


ensembl_gene_id: DespoDRAFT_02159
symbol: EIM64044.1
gene_biotype: protein_coding
description:
  MAF protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.


ensembl_gene_id: DespoDRAFT_02160
symbol: EIM64045.1
gene_biotype: protein_coding
description:
  RNA methyltransferase, RsmE family; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.


ensembl_gene_id: DespoDRAFT_02164
symbol: EIM64048.1
gene_biotype: protein_coding
description:
  Multisubunit Na+/H+ antiporter, MnhF subunit; PFAM: Multiple resistance and pH regulation protein F (MrpF / PhaF).


ensembl_gene_id: DespoDRAFT_02167
symbol: EIM64051.1
gene_biotype: protein_coding
description:
  Multisubunit Na+/H+ antiporter, MnhC subunit; PFAM: NADH-ubiquinone/plastoquinone oxidoreductase chain 4L.


ensembl_gene_id: DespoDRAFT_02169
symbol: EIM64053.1
gene_biotype: protein_coding
description:
  NADH:ubiquinone oxidoreductase subunit 5 (chain L)/multisubunit Na+/H+ antiporter, MnhA subunit; PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains; NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus.


ensembl_gene_id: DespoDRAFT_02172
symbol: EIM64056.1
gene_biotype: protein_coding
description:
  Glycoside/pentoside/hexuronide transporter; PFAM: Major Facilitator Superfamily; TIGRFAM: sugar (Glycoside-Pentoside-Hexuronide) transporter.


ensembl_gene_id: DespoDRAFT_02176
symbol: EIM64060.1
gene_biotype: protein_coding
description:
  PFAM: Pyridoxal-dependent decarboxylase, C-terminal sheet domain; Pyridoxal-dependent decarboxylase, pyridoxal binding domain; Belongs to the Orn/Lys/Arg decarboxylase class-II family.


ensembl_gene_id: DespoDRAFT_02177
symbol: EIM64061.1
gene_biotype: protein_coding
description:
  Na+/phosphate symporter; PFAM: Na+/Pi-cotransporter; TIGRFAM: Na/Pi-cotransporter; manually curated.


ensembl_gene_id: DespoDRAFT_02181
symbol: rsmG
gene_biotype: protein_coding
description:
  16S rRNA (guanine(527)-N(7))-methyltransferase GidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.


ensembl_gene_id: DespoDRAFT_02182
symbol: ileS
gene_biotype: protein_coding
description:
  isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.


ensembl_gene_id: DespoDRAFT_02183
symbol: lspA
gene_biotype: protein_coding
description:
  Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.


ensembl_gene_id: DespoDRAFT_02184
symbol: lgt
gene_biotype: protein_coding
description:
  Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.


ensembl_gene_id: DespoDRAFT_02186
symbol: EIM64070.1
gene_biotype: protein_coding
description:
  PFAM: Pyruvate kinase, barrel domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family.


ensembl_gene_id: DespoDRAFT_02187
symbol: EIM64071.1
gene_biotype: protein_coding
description:
  Putative domain HDIG-containing protein; PFAM: Cache domain; HD domain; PAS fold; TIGRFAM: PAS domain S-box; uncharacterized domain HDIG.


ensembl_gene_id: DespoDRAFT_02193
symbol: EIM64077.1
gene_biotype: protein_coding
description:
  FAD/FMN-dependent dehydrogenase; PFAM: Cysteine-rich domain; FAD binding domain; Protein of unknown function (DUF3683); FAD linked oxidases, C-terminal domain.


ensembl_gene_id: DespoDRAFT_02194
symbol: prfC
gene_biotype: protein_coding
description:
  Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.


ensembl_gene_id: DespoDRAFT_02204
symbol: EIM64083.1
gene_biotype: protein_coding
description:
  HIT family hydrolase, diadenosine tetraphosphate hydrolase; PFAM: Scavenger mRNA decapping enzyme C-term binding.


ensembl_gene_id: DespoDRAFT_02209
symbol: EIM64088.1
gene_biotype: protein_coding
description:
  Glycine cleavage system protein P; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.


ensembl_gene_id: DespoDRAFT_02210
symbol: gcvH
gene_biotype: protein_coding
description:
  Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.


ensembl_gene_id: DespoDRAFT_02211
symbol: EIM64090.1
gene_biotype: protein_coding
description:
  PFAM: Aminomethyltransferase folate-binding domain; TIGRFAM: glycine cleavage system T protein; manually curated; Belongs to the GcvT family.


ensembl_gene_id: DespoDRAFT_02215
symbol: EIM64094.1
gene_biotype: protein_coding
description:
  PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) synthase III; Belongs to the thiolase-like superfamily. FabH family.


ensembl_gene_id: DespoDRAFT_02218
symbol: glmM
gene_biotype: protein_coding
description:
  Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.


ensembl_gene_id: DespoDRAFT_02219
symbol: EIM64098.1
gene_biotype: protein_coding
description:
  ABC-type uncharacterized transport system, permease component; PFAM: Uncharacterised protein family (UPF0014).


ensembl_gene_id: DespoDRAFT_02220
symbol: EIM64099.1
gene_biotype: protein_coding
description:
  FtsH-interacting integral membrane protein; PFAM: Uncharacterised protein family UPF0005; Belongs to the BI1 family.


ensembl_gene_id: DespoDRAFT_02243
symbol: EIM64118.1
gene_biotype: protein_coding
description:
  23S rRNA m2A2503 methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.


ensembl_gene_id: DespoDRAFT_02244
symbol: EIM64119.1
gene_biotype: protein_coding
description:
  Membrane protein TerC, possibly involved in tellurium resistance; PFAM: Integral membrane protein TerC family.


ensembl_gene_id: DespoDRAFT_02247
symbol: EIM64122.1
gene_biotype: protein_coding
description:
  Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.


ensembl_gene_id: DespoDRAFT_02248
symbol: EIM64123.1
gene_biotype: protein_coding
description:
  PFAM: Uncharacterised protein family UPF0047; TIGRFAM: secondary thiamine-phosphate synthase enzyme; manually curated.


ensembl_gene_id: DespoDRAFT_02259
symbol: EIM64134.1
gene_biotype: protein_coding
description:
  PFAM: Acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.


ensembl_gene_id: DespoDRAFT_02261
symbol: rsmH
gene_biotype: protein_coding
description:
  S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.


ensembl_gene_id: DespoDRAFT_02263
symbol: EIM64138.1
gene_biotype: protein_coding
description:
  Cell division protein FtsI/penicillin-binding protein 2; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain.


ensembl_gene_id: DespoDRAFT_02264
symbol: murF
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.


ensembl_gene_id: DespoDRAFT_02265
symbol: mraY
gene_biotype: protein_coding
description:
  phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.


ensembl_gene_id: DespoDRAFT_02266
symbol: murD
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.


ensembl_gene_id: DespoDRAFT_02268
symbol: murG
gene_biotype: protein_coding
description:
  Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.


ensembl_gene_id: DespoDRAFT_02272
symbol: ftsA
gene_biotype: protein_coding
description:
  Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.


ensembl_gene_id: DespoDRAFT_02273
symbol: ftsZ
gene_biotype: protein_coding
description:
  Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.


ensembl_gene_id: DespoDRAFT_02274
symbol: deaD
gene_biotype: protein_coding
description:
  DNA/RNA helicase, superfamily II; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.


ensembl_gene_id: DespoDRAFT_02282
symbol: EIM64155.1
gene_biotype: protein_coding
description:
  PFAM: GAF domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain.


ensembl_gene_id: DespoDRAFT_02285
symbol: EIM64158.1
gene_biotype: protein_coding
description:
  Dehydrogenase of unknown specificity; Short-chain alcohol dehydrogenase like; PFAM: Polyketide cyclase / dehydrase and lipid transport; short chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: DespoDRAFT_02289
symbol: aqpZ
gene_biotype: protein_coding
description:
  MIP family channel protein; Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity; Belongs to the MIP/aquaporin (TC 1.A.8) family.


ensembl_gene_id: DespoDRAFT_02299
symbol: EIM64167.1
gene_biotype: protein_coding
description:
  CBS domain-containing protein; PFAM: CBS domain; Domain of unknown function DUF21; Transporter associated domain.


ensembl_gene_id: DespoDRAFT_02300
symbol: EIM64168.1
gene_biotype: protein_coding
description:
  lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: DespoDRAFT_02302
symbol: lpxA
gene_biotype: protein_coding
description:
  acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: DespoDRAFT_02303
symbol: lpxD
gene_biotype: protein_coding
description:
  UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily.


ensembl_gene_id: DespoDRAFT_02306
symbol: lolD
gene_biotype: protein_coding
description:
  ABC-type antimicrobial peptide transport system, ATPase component; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner. Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.


ensembl_gene_id: DespoDRAFT_02307
symbol: EIM64175.1
gene_biotype: protein_coding
description:
  PFAM: Predicted permease; TIGRFAM: lipoprotein releasing system, transmembrane protein, LolC/E family.


ensembl_gene_id: DespoDRAFT_02308
symbol: lysS
gene_biotype: protein_coding
description:
  lysyl-tRNA synthetase (class II); PFAM: tRNA synthetases class II (D, K and N); OB-fold nucleic acid binding domain; TIGRFAM: lysyl-tRNA synthetase, eukaryotic and non-spirochete bacterial; Belongs to the class-II aminoacyl-tRNA synthetase family.


ensembl_gene_id: DespoDRAFT_02311
symbol: EIM64179.1
gene_biotype: protein_coding
description:
  Signal transduction histidine kinase, nitrogen specific; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.


ensembl_gene_id: DespoDRAFT_02312
symbol: EIM64180.1
gene_biotype: protein_coding
description:
  Type II secretory pathway, component PulF; PFAM: Bacterial type II secretion system protein F domain.


ensembl_gene_id: DespoDRAFT_02313
symbol: EIM64181.1
gene_biotype: protein_coding
description:
  tRNA nucleotidyltransferase/poly(A) polymerase; PFAM: DHH family; CBS domain; Poly A polymerase head domain; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.


ensembl_gene_id: DespoDRAFT_02314
symbol: trpS
gene_biotype: protein_coding
description:
  tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: DespoDRAFT_02315
symbol: EIM64183.1
gene_biotype: protein_coding
description:
  PFAM: RNA pseudouridylate synthase; S4 domain; TIGRFAM: pseudouridine synthase; Belongs to the pseudouridine synthase RsuA family.


ensembl_gene_id: DespoDRAFT_02316
symbol: argJ
gene_biotype: protein_coding
description:
  Glutamate N-acetyltransferase/amino-acid acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.


ensembl_gene_id: DespoDRAFT_02330
symbol: EIM64195.1
gene_biotype: protein_coding
description:
  ABC-type multidrug transport system, ATPase and permease component; PFAM: ABC transporter transmembrane region; ABC transporter; TIGRFAM: lipid A export permease/ATP-binding protein MsbA.


ensembl_gene_id: DespoDRAFT_02333
symbol: EIM64198.1
gene_biotype: protein_coding
description:
  TIGR00255 family protein; PFAM: YicC-like family, N-terminal region; Domain of unknown function (DUF1732); TIGRFAM: TIGR00255 family protein.


ensembl_gene_id: DespoDRAFT_02336
symbol: EIM64201.1
gene_biotype: protein_coding
description:
  rRNA methylase, putative, group 3; PFAM: SpoU rRNA Methylase family; RNA 2'-O ribose methyltransferase substrate binding; TIGRFAM: rRNA methylase, putative, group 3; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.


ensembl_gene_id: DespoDRAFT_02337
symbol: EIM64202.1
gene_biotype: protein_coding
description:
  Putative amidophosphoribosyltransferase; PFAM: Phosphoribosyl transferase domain; TIGRFAM: comF family protein.


ensembl_gene_id: DespoDRAFT_02338
symbol: EIM64203.1
gene_biotype: protein_coding
description:
  DNA/RNA helicase, superfamily II; PFAM: Helicase conserved C-terminal domain; SNF2 family N-terminal domain.


ensembl_gene_id: DespoDRAFT_02343
symbol: EIM64208.1
gene_biotype: protein_coding
description:
  Glucosamine 6-phosphate synthetase; PFAM: SIS domain; Glutamine amidotransferases class-II; contains amidotransferase and phosphosugar isomerase domains.


ensembl_gene_id: DespoDRAFT_02344
symbol: EIM64209.1
gene_biotype: protein_coding
description:
  Cell division protein FtsI/penicillin-binding protein 2; PFAM: Penicillin binding protein transpeptidase domain.


ensembl_gene_id: DespoDRAFT_02345
symbol: metG
gene_biotype: protein_coding
description:
  Protein containing C-terminal region/beta chain of methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.


ensembl_gene_id: DespoDRAFT_02350
symbol: lptD
gene_biotype: protein_coding
description:
  Organic solvent tolerance protein OstA; Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane; Belongs to the LptD family.


ensembl_gene_id: DespoDRAFT_02351
symbol: EIM64216.1
gene_biotype: protein_coding
description:
  Cysteine synthase; PFAM: tRNA synthetases class I (C) catalytic domain; Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthases; cysteinyl-tRNA synthetase; cysteine synthase B.


ensembl_gene_id: DespoDRAFT_02374
symbol: recR
gene_biotype: protein_coding
description:
  Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.


ensembl_gene_id: DespoDRAFT_02375
symbol: EIM64234.1
gene_biotype: protein_coding
description:
  DNA-binding protein, YbaB/EbfC family; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.


ensembl_gene_id: DespoDRAFT_02376
symbol: dnaX
gene_biotype: protein_coding
description:
  DNA polymerase III, subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.


ensembl_gene_id: DespoDRAFT_02377
symbol: EIM64236.1
gene_biotype: protein_coding
description:
  General secretion pathway protein G; PFAM: Prokaryotic N-terminal methylation motif; Bacterial type II secretion system protein G; TIGRFAM: general secretion pathway protein G; prepilin-type N-terminal cleavage/methylation domain.


ensembl_gene_id: DespoDRAFT_02379
symbol: EIM64238.1
gene_biotype: protein_coding
description:
  PFAM: Prokaryotic N-terminal methylation motif; TIGRFAM: general secretion pathway protein I; prepilin-type N-terminal cleavage/methylation domain; overlaps another CDS with the same product name.


ensembl_gene_id: DespoDRAFT_02380
symbol: EIM64239.1
gene_biotype: protein_coding
description:
  PFAM: Prokaryotic N-terminal methylation motif; TIGRFAM: prepilin-type N-terminal cleavage/methylation domain; overlaps another CDS with the same product name.


ensembl_gene_id: DespoDRAFT_02384
symbol: EIM64243.1
gene_biotype: protein_coding
description:
  General secretion pathway protein D; PFAM: Bacterial type II/III secretion system short domain; Bacterial type II and III secretion system protein; TIGRFAM: general secretion pathway protein D.


ensembl_gene_id: DespoDRAFT_02385
symbol: EIM64244.1
gene_biotype: protein_coding
description:
  General secretory pathway protein E; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.


ensembl_gene_id: DespoDRAFT_02390
symbol: EIM64247.1
gene_biotype: protein_coding
description:
  NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.


ensembl_gene_id: DespoDRAFT_02393
symbol: EIM64250.1
gene_biotype: protein_coding
description:
  Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.


ensembl_gene_id: DespoDRAFT_02400
symbol: EIM64257.1
gene_biotype: protein_coding
description:
  Inosine guanosine and xanthosine phosphorylase family protein; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.


ensembl_gene_id: DespoDRAFT_02406
symbol: EIM64263.1
gene_biotype: protein_coding
description:
  Outer membrane protein/peptidoglycan-associated (lipo)protein; PFAM: von Willebrand factor type A domain; OmpA family.


ensembl_gene_id: DespoDRAFT_02408
symbol: EIM64265.1
gene_biotype: protein_coding
description:
  Histidine kinase,HAMP domain-containing protein,histidine kinase; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.


ensembl_gene_id: DespoDRAFT_02420
symbol: msrB
gene_biotype: protein_coding
description:
  methionine-R-sulfoxide reductase/methionine-S-sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.


ensembl_gene_id: DespoDRAFT_02422
symbol: EIM64276.1
gene_biotype: protein_coding
description:
  Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains; PFAM: Sigma-54 interaction domain.


ensembl_gene_id: DespoDRAFT_02423
symbol: EIM64277.1
gene_biotype: protein_coding
description:
  Protein-tyrosine-phosphatase; PFAM: Low molecular weight phosphotyrosine protein phosphatase; TIGRFAM: arsenate reductase (thioredoxin).


ensembl_gene_id: DespoDRAFT_02424
symbol: ppk
gene_biotype: protein_coding
description:
  Polyphosphate kinase 1; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family.


ensembl_gene_id: DespoDRAFT_02425
symbol: der
gene_biotype: protein_coding
description:
  Ribosome-associated GTPase EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.


ensembl_gene_id: DespoDRAFT_02429
symbol: gyrA
gene_biotype: protein_coding
description:
  DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.


ensembl_gene_id: DespoDRAFT_02430
symbol: EIM64284.1
gene_biotype: protein_coding
description:
  DNA repair protein radc; PFAM: Protein of unknown function (DUF2466); TIGRFAM: DNA repair protein radc; Belongs to the UPF0758 family.


ensembl_gene_id: DespoDRAFT_02434
symbol: EIM64288.1
gene_biotype: protein_coding
description:
  Acetyltransferase, N-acetylglutamate synthase; PFAM: Acetyltransferase (GNAT) family; Belongs to the acetyltransferase family.


ensembl_gene_id: DespoDRAFT_02437
symbol: EIM64291.1
gene_biotype: protein_coding
description:
  Methylase of chemotaxis methyl-accepting protein; PFAM: CheR methyltransferase, SAM binding domain; CheR methyltransferase, all-alpha domain.


ensembl_gene_id: DespoDRAFT_02440
symbol: EIM64294.1
gene_biotype: protein_coding
description:
  Chemotaxis protein histidine kinase-like protein; PFAM: CheW-like domain; Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Signal transducing histidine kinase, homodimeric domain; Hpt domain.


ensembl_gene_id: DespoDRAFT_02448
symbol: rpmG
gene_biotype: protein_coding
description:
  PFAM: Ribosomal protein L33; TIGRFAM: ribosomal protein L33, bacterial type; manually curated; Belongs to the bacterial ribosomal protein bL33 family.


ensembl_gene_id: DespoDRAFT_02450
symbol: secE
gene_biotype: protein_coding
description:
  Preprotein translocase, SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.


ensembl_gene_id: DespoDRAFT_02451
symbol: nusG
gene_biotype: protein_coding
description:
  Transcription termination/antitermination factor NusG; Participates in transcription elongation, termination and antitermination.


ensembl_gene_id: DespoDRAFT_02452
symbol: rplK
gene_biotype: protein_coding
description:
  50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.


ensembl_gene_id: DespoDRAFT_02453
symbol: rplA
gene_biotype: protein_coding
description:
  Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.


ensembl_gene_id: DespoDRAFT_02454
symbol: rplJ
gene_biotype: protein_coding
description:
  Ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.


ensembl_gene_id: DespoDRAFT_02455
symbol: rplL
gene_biotype: protein_coding
description:
  Ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family.


ensembl_gene_id: DespoDRAFT_02456
symbol: rpoB
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: DespoDRAFT_02457
symbol: rpoC
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase, beta'' subunit, predominant form; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: DespoDRAFT_02458
symbol: rpsL
gene_biotype: protein_coding
description:
  Ribosomal protein S12, bacterial/organelle; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.


ensembl_gene_id: DespoDRAFT_02459
symbol: rpsG
gene_biotype: protein_coding
description:
  Ribosomal protein S7, bacterial/organelle; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.


ensembl_gene_id: DespoDRAFT_02460
symbol: tuf
gene_biotype: protein_coding
description:
  Translation elongation factor TU; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.


ensembl_gene_id: DespoDRAFT_02461
symbol: rpsJ
gene_biotype: protein_coding
description:
  Ribosomal protein S10, bacterial/organelle; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.


ensembl_gene_id: DespoDRAFT_02462
symbol: rplC
gene_biotype: protein_coding
description:
  50S ribosomal protein L3, bacterial; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.


ensembl_gene_id: DespoDRAFT_02464
symbol: rplW
gene_biotype: protein_coding
description:
  Ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.


ensembl_gene_id: DespoDRAFT_02465
symbol: rplB
gene_biotype: protein_coding
description:
  Ribosomal protein L2, bacterial/organellar; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.


ensembl_gene_id: DespoDRAFT_02466
symbol: rpsS
gene_biotype: protein_coding
description:
  Ribosomal protein S19, bacterial/organelle; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.


ensembl_gene_id: DespoDRAFT_02467
symbol: rplV
gene_biotype: protein_coding
description:
  Ribosomal protein L22, bacterial type; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.


ensembl_gene_id: DespoDRAFT_02468
symbol: rpsC
gene_biotype: protein_coding
description:
  Ribosomal protein S3, bacterial type; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.


ensembl_gene_id: DespoDRAFT_02469
symbol: rplP
gene_biotype: protein_coding
description:
  Ribosomal protein L16, bacterial/organelle; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.


ensembl_gene_id: DespoDRAFT_02470
symbol: rpmC
gene_biotype: protein_coding
description:
  PFAM: Ribosomal L29 protein; TIGRFAM: ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family.


ensembl_gene_id: DespoDRAFT_02471
symbol: rpsQ
gene_biotype: protein_coding
description:
  30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.


ensembl_gene_id: DespoDRAFT_02472
symbol: rplN
gene_biotype: protein_coding
description:
  Ribosomal protein L14, bacterial/organelle; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.


ensembl_gene_id: DespoDRAFT_02473
symbol: rplX
gene_biotype: protein_coding
description:
  Ribosomal protein L24, bacterial/organelle; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.


ensembl_gene_id: DespoDRAFT_02474
symbol: rplE
gene_biotype: protein_coding
description:
  Ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.


ensembl_gene_id: DespoDRAFT_02475
symbol: rpsZ
gene_biotype: protein_coding
description:
  Ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.


ensembl_gene_id: DespoDRAFT_02476
symbol: rpsH
gene_biotype: protein_coding
description:
  Ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.


ensembl_gene_id: DespoDRAFT_02477
symbol: rplF
gene_biotype: protein_coding
description:
  Ribosomal protein L6, bacterial type; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.


ensembl_gene_id: DespoDRAFT_02478
symbol: rplR
gene_biotype: protein_coding
description:
  Ribosomal protein L18, bacterial type; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.


ensembl_gene_id: DespoDRAFT_02479
symbol: rpsE
gene_biotype: protein_coding
description:
  Ribosomal protein S5, bacterial/organelle type; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.


ensembl_gene_id: DespoDRAFT_02481
symbol: rplO
gene_biotype: protein_coding
description:
  Ribosomal protein L15, bacterial/organelle; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.


ensembl_gene_id: DespoDRAFT_02482
symbol: secY
gene_biotype: protein_coding
description:
  Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.


ensembl_gene_id: DespoDRAFT_02483
symbol: infA
gene_biotype: protein_coding
description:
  Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.


ensembl_gene_id: DespoDRAFT_02484
symbol: rpmJ
gene_biotype: protein_coding
description:
  PFAM: Ribosomal protein L36; TIGRFAM: ribosomal protein L36, bacterial type; Belongs to the bacterial ribosomal protein bL36 family.


ensembl_gene_id: DespoDRAFT_02485
symbol: rpsM
gene_biotype: protein_coding
description:
  30S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family.


ensembl_gene_id: DespoDRAFT_02486
symbol: rpsK
gene_biotype: protein_coding
description:
  30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.


ensembl_gene_id: DespoDRAFT_02487
symbol: rpsD
gene_biotype: protein_coding
description:
  Ribosomal protein S4, bacterial/organelle type; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.


ensembl_gene_id: DespoDRAFT_02488
symbol: rpoA
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: DespoDRAFT_02491
symbol: EIM64339.1
gene_biotype: protein_coding
description:
  Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.


ensembl_gene_id: DespoDRAFT_02492
symbol: EIM64340.1
gene_biotype: protein_coding
description:
  uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase.


ensembl_gene_id: DespoDRAFT_02493
symbol: hemC
gene_biotype: protein_coding
description:
  Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.


ensembl_gene_id: DespoDRAFT_02495
symbol: EIM64343.1
gene_biotype: protein_coding
description:
  Amidohydrolase; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain; TIGRFAM: amidohydrolase; Belongs to the peptidase M20A family.


ensembl_gene_id: DespoDRAFT_02497
symbol: gmhA
gene_biotype: protein_coding
description:
  Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.


ensembl_gene_id: DespoDRAFT_02499
symbol: selA
gene_biotype: protein_coding
description:
  seryl-tRNA(Sec) selenium transferase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.


ensembl_gene_id: DespoDRAFT_02500
symbol: cheD-4
gene_biotype: protein_coding
description:
  Putative domain HDIG-containing protein; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.


ensembl_gene_id: DespoDRAFT_02502
symbol: pyrF
gene_biotype: protein_coding
description:
  Orotidine 5''-phosphate decarboxylase, subfamily 1; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.


ensembl_gene_id: DespoDRAFT_02503
symbol: EIM64351.1
gene_biotype: protein_coding
description:
  PFAM: ACT domain; Amino acid kinase family; TIGRFAM: aspartate kinase, monofunctional class; aspartate kinase; Belongs to the aspartokinase family.


ensembl_gene_id: DespoDRAFT_02505
symbol: nnrD
gene_biotype: protein_coding
description:
  yjeF-like protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.  Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimer [...]


ensembl_gene_id: DespoDRAFT_02507
symbol: EIM64355.1
gene_biotype: protein_coding
description:
  ABC-type uncharacterized transport system, permease and ATPase component; PFAM: ABC transporter; ABC transporter transmembrane region 2.


ensembl_gene_id: DespoDRAFT_02510
symbol: ispF
gene_biotype: protein_coding
description:
  2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).


ensembl_gene_id: DespoDRAFT_02511
symbol: cysS
gene_biotype: protein_coding
description:
  PFAM: tRNA synthetases class I (C) catalytic domain; DALR domain; TIGRFAM: cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: DespoDRAFT_02512
symbol: glnS
gene_biotype: protein_coding
description:
  PFAM: tRNA synthetases class I (E and Q), catalytic domain; tRNA synthetases class I (E and Q), anti-codon binding domain; TIGRFAM: glutaminyl-tRNA synthetase.


ensembl_gene_id: DespoDRAFT_02514
symbol: uvrB
gene_biotype: protein_coding
description:
  Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]


ensembl_gene_id: DespoDRAFT_02527
symbol: uvrC
gene_biotype: protein_coding
description:
  Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.


ensembl_gene_id: DespoDRAFT_02531
symbol: pdxJ
gene_biotype: protein_coding
description:
  Pyridoxine 5''-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.


ensembl_gene_id: DespoDRAFT_02532
symbol: ybeY
gene_biotype: protein_coding
description:
  Metalloprotein, YbeY/UPF0054 family; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.


ensembl_gene_id: DespoDRAFT_02533
symbol: EIM64379.1
gene_biotype: protein_coding
description:
  Putative domain HDIG-containing protein; PFAM: 7TM-HD extracellular; HD domain; 7TM receptor with intracellular HD hydrolase; TIGRFAM: uncharacterized domain HDIG.


ensembl_gene_id: DespoDRAFT_02536
symbol: EIM64382.1
gene_biotype: protein_coding
description:
  MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase domain; TIGRFAM: MazG family protein.


ensembl_gene_id: DespoDRAFT_02544
symbol: EIM64390.1
gene_biotype: protein_coding
description:
  Electron transfer flavoprotein, alpha subunit; PFAM: Electron transfer flavoprotein domain; Electron transfer flavoprotein FAD-binding domain.


ensembl_gene_id: DespoDRAFT_02545
symbol: thyA
gene_biotype: protein_coding
description:
  Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.


ensembl_gene_id: DespoDRAFT_02549
symbol: cas1
gene_biotype: protein_coding
description:
  CRISPR-associated endonuclease Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.


ensembl_gene_id: DespoDRAFT_02557
symbol: cas2
gene_biotype: protein_coding
description:
  CRISPR-associated endoribonuclease Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.


ensembl_gene_id: DespoDRAFT_02561
symbol: EIM64407.1
gene_biotype: protein_coding
description:
  PFAM: Protein of unknown function (DUF310); TIGRFAM: CRISPR type III-A/MTUBE-associated protein Csm2.


ensembl_gene_id: DespoDRAFT_02567
symbol: EIM64412.1
gene_biotype: protein_coding
description:
  PFAM: CRISPR-associated protein (Cas_APE2256); TIGRFAM: putative CRISPR-associated protein, APE2256 family.


ensembl_gene_id: DespoDRAFT_02568
symbol: EIM64413.1
gene_biotype: protein_coding
description:
  PFAM: CRISPR-associated (Cas) DxTHG family; TIGRFAM: CRISPR-associated protein, TM1812 family; CRISPR-associated DxTHG motif protein.


ensembl_gene_id: DespoDRAFT_02570
symbol: EIM64415.1
gene_biotype: protein_coding
description:
  PFAM: CRISPR-associated protein (Cas_Cmr5); TIGRFAM: CRISPR type III-B/RAMP module-associated protein Cmr5.


ensembl_gene_id: DespoDRAFT_02572
symbol: EIM64417.1
gene_biotype: protein_coding
description:
  PFAM: CRISPR-associated protein (Cas_Cmr3); TIGRFAM: CRISPR type III-B/RAMP module-associated protein Cmr3.


ensembl_gene_id: DespoDRAFT_02579
symbol: EIM64424.1
gene_biotype: protein_coding
description:
  Anaerobic dehydrogenase, typically selenocysteine-containing; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: DespoDRAFT_02581
symbol: tatC
gene_biotype: protein_coding
description:
  Twin arginine targeting protein translocase subunit TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.


ensembl_gene_id: DespoDRAFT_02582
symbol: tatA-2
gene_biotype: protein_coding
description:
  Sec-independent protein secretion pathway component; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.


ensembl_gene_id: DespoDRAFT_02583
symbol: rhlB
gene_biotype: protein_coding
description:
  DNA/RNA helicase, superfamily II; DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA.


ensembl_gene_id: DespoDRAFT_02590
symbol: EIM64435.1
gene_biotype: protein_coding
description:
  Penicillin-binding protein, 1A family; PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase; TIGRFAM: penicillin-binding protein, 1A family.


ensembl_gene_id: DespoDRAFT_02595
symbol: EIM64440.1
gene_biotype: protein_coding
description:
  Selenium metabolism protein YedF; PFAM: SirA-like protein; DsrE/DsrF-like family; TIGRFAM: selenium metabolism protein YedF; Belongs to the sulfur carrier protein TusA family.


ensembl_gene_id: DespoDRAFT_02600
symbol: EIM64445.1
gene_biotype: protein_coding
description:
  Fe2+/Zn2+ uptake regulation protein; PFAM: FeoA domain; Ferric uptake regulator family; Belongs to the Fur family.


ensembl_gene_id: DespoDRAFT_02610
symbol: EIM64454.1
gene_biotype: protein_coding
description:
  Type IV pilus secretin PilQ/competence protein; PFAM: Bacterial type II/III secretion system short domain; Secretin and TonB N terminus short domain; Bacterial type II and III secretion system protein; TIGRFAM: type IV pilus secretin (or competence protein) PilQ.


ensembl_gene_id: DespoDRAFT_02611
symbol: EIM64455.1
gene_biotype: protein_coding
description:
  Tfp pilus assembly protein PilF; PFAM: Tetratricopeptide repeat; TIGRFAM: type IV pilus biogenesis/stability protein PilW.


ensembl_gene_id: DespoDRAFT_02614
symbol: serS
gene_biotype: protein_coding
description:
  seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).


ensembl_gene_id: DespoDRAFT_02615
symbol: EIM64459.1
gene_biotype: protein_coding
description:
  5,10-methenyltetrahydrofolate synthetase; PFAM: 5-formyltetrahydrofolate cyclo-ligase family; TIGRFAM: 5,10-methenyltetrahydrofolate synthetase.


ensembl_gene_id: DespoDRAFT_02617
symbol: pcm
gene_biotype: protein_coding
description:
  protein-L-isoaspartate and D-aspartate O-methyltransferase; Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.


ensembl_gene_id: DespoDRAFT_02620
symbol: EIM64464.1
gene_biotype: protein_coding
description:
  Disulfide bond chaperone; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress; Belongs to the HSP33 family.


ensembl_gene_id: DespoDRAFT_02622
symbol: EIM64466.1
gene_biotype: protein_coding
description:
  PAS domain S-box; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box.


ensembl_gene_id: DespoDRAFT_02624
symbol: EIM64468.1
gene_biotype: protein_coding
description:
  Mg chelatase-related protein; PFAM: Magnesium chelatase, subunit ChlI; TIGRFAM: Mg chelatase-related protein.


ensembl_gene_id: DespoDRAFT_02625
symbol: lpxC
gene_biotype: protein_coding
description:
  UDP-3-0-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family.


ensembl_gene_id: DespoDRAFT_02629
symbol: EIM64473.1
gene_biotype: protein_coding
description:
  RNA methyltransferase, RsmD family; PFAM: Conserved hypothetical protein 95; TIGRFAM: RNA methyltransferase, RsmD family; manually curated.


ensembl_gene_id: DespoDRAFT_02630
symbol: coaD
gene_biotype: protein_coding
description:
  Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.


ensembl_gene_id: DespoDRAFT_02632
symbol: EIM64476.1
gene_biotype: protein_coding
description:
  N-methylhydantoinase A/acetone carboxylase, beta subunit; PFAM: Hydantoinase/oxoprolinase; Hydantoinase/oxoprolinase N-terminal region.


ensembl_gene_id: DespoDRAFT_02634
symbol: EIM64478.1
gene_biotype: protein_coding
description:
  lysyl-tRNA synthetase-like protein GenX; PFAM: tRNA synthetases class II (D, K and N); TIGRFAM: EF-P lysine aminoacylase GenX.


ensembl_gene_id: DespoDRAFT_02637
symbol: argG
gene_biotype: protein_coding
description:
  PFAM: Arginosuccinate synthase; TIGRFAM: argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.


ensembl_gene_id: DespoDRAFT_02642
symbol: EIM64486.1
gene_biotype: protein_coding
description:
  Translation elongation factor P/translation initiation factor 5A; PFAM: Elongation factor P, C-terminal; Elongation factor P (EF-P) KOW-like domain; Elongation factor P (EF-P) OB domain; TIGRFAM: elongation factor P-like protein YeiP; translation elongation factor P.


ensembl_gene_id: DespoDRAFT_02644
symbol: EIM64488.1
gene_biotype: protein_coding
description:
  Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase component; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain.


ensembl_gene_id: DespoDRAFT_02653
symbol: EIM64496.1
gene_biotype: protein_coding
description:
  PFAM: Uncharacterized protein conserved in bacteria N-term (DUF3322); Uncharacterized protein conserved in bacteria C-term(DUF2220).


ensembl_gene_id: DespoDRAFT_02674
symbol: metK
gene_biotype: protein_coding
description:
  S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.


ensembl_gene_id: DespoDRAFT_02675
symbol: ahcY
gene_biotype: protein_coding
description:
  Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.


ensembl_gene_id: DespoDRAFT_02677
symbol: EIM64514.1
gene_biotype: protein_coding
description:
  PFAM: Radical SAM superfamily; Dinitrogenase iron-molybdenum cofactor; TIGRFAM: nitrogenase cofactor biosynthesis protein NifB.


ensembl_gene_id: DespoDRAFT_02680
symbol: EIM64517.1
gene_biotype: protein_coding
description:
  HAD-superfamily hydrolase, subfamily IIB; PFAM: Sucrose-6F-phosphate phosphohydrolase; TIGRFAM: sucrose-6F-phosphate phosphohydrolase; HAD-superfamily hydrolase, subfamily IIB; overlaps another CDS with the same product name.


ensembl_gene_id: DespoDRAFT_02681
symbol: EIM64518.1
gene_biotype: protein_coding
description:
  HAD-superfamily hydrolase, subfamily IIB; PFAM: Sucrose synthase; Glycosyl transferases group 1; Sucrose-6F-phosphate phosphohydrolase; TIGRFAM: sucrose-6F-phosphate phosphohydrolase; sucrose-phosphate synthase, putative, glycosyltransferase domain; HAD-superfamily hydrolase, subfamily IIB; sucrose phosphate synthase, sucrose phosphatase-like domain, bacterial; overlaps another CDS with the same product name.


ensembl_gene_id: DespoDRAFT_02687
symbol: EIM64524.1
gene_biotype: protein_coding
description:
  2-oxoacid:acceptor oxidoreductase, alpha subunit; PFAM: domain; Transketolase, C-terminal domain; Pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, alpha subunit.


ensembl_gene_id: DespoDRAFT_02688
symbol: EIM64525.1
gene_biotype: protein_coding
description:
  2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate family; PFAM: Pyruvate ferredoxin oxidoreductase beta subunit C terminal; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate family.


ensembl_gene_id: DespoDRAFT_02689
symbol: EIM64526.1
gene_biotype: protein_coding
description:
  Alpha-hydroxyacid dehydrogenase, FMN-dependent L-lactate dehydrogenase; PFAM: FMN-dependent dehydrogenase.


ensembl_gene_id: DespoDRAFT_02693
symbol: EIM64529.1
gene_biotype: protein_coding
description:
  PFAM: Domain of unknown function (DUF3458); Peptidase family M1; TIGRFAM: aminopeptidase N, Escherichia coli type.


ensembl_gene_id: DespoDRAFT_02694
symbol: EIM64530.1
gene_biotype: protein_coding
description:
  Uncharacterized protein involved in an early stage of isoprenoid biosynthesis; PFAM: DJ-1/PfpI family.


ensembl_gene_id: DespoDRAFT_02695
symbol: EIM64531.1
gene_biotype: protein_coding
description:
  Nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; TIGRFAM: nucleotide sugar dehydrogenase.


ensembl_gene_id: DespoDRAFT_02699
symbol: EIM64534.1
gene_biotype: protein_coding
description:
  Putative O-methyltransferase; PFAM: Methyltransferase small domain; manually curated; Belongs to the methyltransferase superfamily.


ensembl_gene_id: DespoDRAFT_02706
symbol: groS
gene_biotype: protein_coding
description:
  Co-chaperonin GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.


ensembl_gene_id: DespoDRAFT_02707
symbol: groL
gene_biotype: protein_coding
description:
  Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.


ensembl_gene_id: DespoDRAFT_02710
symbol: EIM64545.1
gene_biotype: protein_coding
description:
  TolA protein; PFAM: Exonuclease VII, large subunit; TIGRFAM: TolA protein; TonB family C-terminal domain.


ensembl_gene_id: DespoDRAFT_02711
symbol: tolB
gene_biotype: protein_coding
description:
  Tol-pal system beta propeller repeat protein TolB; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: DespoDRAFT_02712
symbol: pal
gene_biotype: protein_coding
description:
  Peptidoglycan-associated lipoprotein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: DespoDRAFT_02714
symbol: ruvC
gene_biotype: protein_coding
description:
  Holliday junction resolvasome, endonuclease subunit; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.


ensembl_gene_id: DespoDRAFT_02715
symbol: ruvA
gene_biotype: protein_coding
description:
  Holliday junction resolvasome, DNA-binding subunit; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.


ensembl_gene_id: DespoDRAFT_02716
symbol: ruvB
gene_biotype: protein_coding
description:
  Holliday junction DNA helicase, RuvB subunit; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.


ensembl_gene_id: DespoDRAFT_02717
symbol: rplM
gene_biotype: protein_coding
description:
  Ribosomal protein L13, bacterial type; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.


ensembl_gene_id: DespoDRAFT_02720
symbol: EIM64555.1
gene_biotype: protein_coding
description:
  Bacterial nucleoid DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.


ensembl_gene_id: DespoDRAFT_02722
symbol: EIM64557.1
gene_biotype: protein_coding
description:
  Zn-dependent hydrolase, glyoxylase; PFAM: Metallo-beta-lactamase superfamily; Rhodanese-like domain.


ensembl_gene_id: DespoDRAFT_02723
symbol: EIM64558.1
gene_biotype: protein_coding
description:
  Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.


ensembl_gene_id: DespoDRAFT_02725
symbol: EIM64560.1
gene_biotype: protein_coding
description:
  Prepilin signal peptidase PulO-like peptidase; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.


ensembl_gene_id: DespoDRAFT_02728
symbol: psd
gene_biotype: protein_coding
description:
  Phosphatidylserine decarboxylase precursor-related protein; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).


ensembl_gene_id: DespoDRAFT_02729
symbol: greA
gene_biotype: protein_coding
description:
  Transcription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.


ensembl_gene_id: DespoDRAFT_02730
symbol: rpoZ
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.


ensembl_gene_id: DespoDRAFT_02731
symbol: EIM64566.1
gene_biotype: protein_coding
description:
  Putative ATPase of the PP-loop superfamily implicated in cell cycle control; PFAM: PP-loop family; Contains selenocysteine; manually curated; Belongs to the TtcA family.


ensembl_gene_id: DespoDRAFT_02733
symbol: EIM64568.1
gene_biotype: protein_coding
description:
  D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4); PFAM: D-Ala-D-Ala carboxypeptidase 3 (S13) family.


ensembl_gene_id: DespoDRAFT_02737
symbol: EIM64572.1
gene_biotype: protein_coding
description:
  Glucose-1-phosphate thymidylyltransferase, short form; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.


ensembl_gene_id: DespoDRAFT_02738
symbol: EIM64573.1
gene_biotype: protein_coding
description:
  dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.


ensembl_gene_id: DespoDRAFT_02739
symbol: EIM64574.1
gene_biotype: protein_coding
description:
  dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family.


ensembl_gene_id: DespoDRAFT_02744
symbol: EIM64579.1
gene_biotype: protein_coding
description:
  Putative nucleoside-diphosphate sugar epimerase; PFAM: CoA binding domain; Polysaccharide biosynthesis protein.


ensembl_gene_id: DespoDRAFT_02745
symbol: EIM64580.1
gene_biotype: protein_coding
description:
  General secretion pathway protein K; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat region.


ensembl_gene_id: DespoDRAFT_02759
symbol: ppnP
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.


ensembl_gene_id: DespoDRAFT_02762
symbol: ndk
gene_biotype: protein_coding
description:
  Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.


ensembl_gene_id: DespoDRAFT_02763
symbol: coaE
gene_biotype: protein_coding
description:
  dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.


ensembl_gene_id: DespoDRAFT_02764
symbol: rho-2
gene_biotype: protein_coding
description:
  Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.


ensembl_gene_id: DespoDRAFT_02766
symbol: prfA
gene_biotype: protein_coding
description:
  Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.


ensembl_gene_id: DespoDRAFT_02767
symbol: prmC
gene_biotype: protein_coding
description:
  protein-(glutamine-N5) methyltransferase, release factor-specific; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.


ensembl_gene_id: DespoDRAFT_02768
symbol: rpsB
gene_biotype: protein_coding
description:
  PFAM: Ribosomal protein S2; TIGRFAM: ribosomal protein S2, bacterial type; Belongs to the universal ribosomal protein uS2 family.


ensembl_gene_id: DespoDRAFT_02769
symbol: tsf
gene_biotype: protein_coding
description:
  Translation elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.


ensembl_gene_id: DespoDRAFT_02771
symbol: frr
gene_biotype: protein_coding
description:
  Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.


ensembl_gene_id: DespoDRAFT_02772
symbol: EIM64596.1
gene_biotype: protein_coding
description:
  Undecaprenyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.


ensembl_gene_id: DespoDRAFT_02774
symbol: dxr
gene_biotype: protein_coding
description:
  1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family.


ensembl_gene_id: DespoDRAFT_02775
symbol: EIM64599.1
gene_biotype: protein_coding
description:
  Putative membrane-associated Zn-dependent protease; PFAM: Peptidase family M50; TIGRFAM: RIP metalloprotease RseP.


ensembl_gene_id: DespoDRAFT_02776
symbol: purL
gene_biotype: protein_coding
description:
  Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL an [...]


ensembl_gene_id: DespoDRAFT_02777
symbol: EIM64601.1
gene_biotype: protein_coding
description:
  Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain; TIGRFAM: phosphoribosylformylglycinamidine synthase I.


ensembl_gene_id: DespoDRAFT_02778
symbol: EIM64602.1
gene_biotype: protein_coding
description:
  Putative endoIII-related endonuclease; PFAM: HhH-GPD superfamily base excision DNA repair protein; Helix-hairpin-helix motif; TIGRFAM: endonuclease III.


ensembl_gene_id: DespoDRAFT_02782
symbol: EIM64605.1
gene_biotype: protein_coding
description:
  PEP-CTERM putative exosortase interaction domain-containing protein; TIGRFAM: PEP-CTERM protein sorting domain.


ensembl_gene_id: DespoDRAFT_02784
symbol: rnj
gene_biotype: protein_coding
description:
  Hypothetical protein; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.


ensembl_gene_id: DespoDRAFT_02792
symbol: argS
gene_biotype: protein_coding
description:
  arginyl-tRNA synthetase; PFAM: DALR anticodon binding domain; Arginyl tRNA synthetase N terminal domain; tRNA synthetases class I (R); TIGRFAM: arginyl-tRNA synthetase.


ensembl_gene_id: DespoDRAFT_02794
symbol: gatC
gene_biotype: protein_coding
description:
  glutamyl-tRNA(Gln) and/or aspartyl-tRNA(Asn) amidotransferase, C subunit; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family.


ensembl_gene_id: DespoDRAFT_02795
symbol: gatA
gene_biotype: protein_coding
description:
  glutamyl-tRNA(Gln) and/or aspartyl-tRNA(Asn) amidotransferase, A subunit; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln).


ensembl_gene_id: DespoDRAFT_02798
symbol: mutL
gene_biotype: protein_coding
description:
  DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.


ensembl_gene_id: DespoDRAFT_02805
symbol: purA
gene_biotype: protein_coding
description:
  Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.


ensembl_gene_id: DespoDRAFT_02806
symbol: tadA
gene_biotype: protein_coding
description:
  Cytosine/adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.


ensembl_gene_id: DespoDRAFT_02807
symbol: hemL
gene_biotype: protein_coding
description:
  Glutamate-1-semialdehyde-2,1-aminomutase; PFAM: Aminotransferase class-III; TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase.


ensembl_gene_id: DespoDRAFT_02808
symbol: EIM64628.1
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; PFAM: Mur ligase family, glutamate ligase domain; Mur ligase family, catalytic domain; Mur ligase middle domain; TIGRFAM: UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso- diaminopimelate ligase; UDP-N-acetylmuramate--alanine ligase.


ensembl_gene_id: DespoDRAFT_02812
symbol: recD
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease V, alpha subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and r [...]


ensembl_gene_id: DespoDRAFT_02845
symbol: EIM64663.1
gene_biotype: protein_coding
description:
  Flagellin/flagellar hook associated protein; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.


ensembl_gene_id: DespoDRAFT_02846
symbol: EIM64664.1
gene_biotype: protein_coding
description:
  Flagellar capping protein; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.


ensembl_gene_id: DespoDRAFT_02851
symbol: EIM64669.1
gene_biotype: protein_coding
description:
  Flagellar hook capping protein; Required for flagellar hook formation. May act as a scaffolding protein.


ensembl_gene_id: DespoDRAFT_02852
symbol: EIM64670.1
gene_biotype: protein_coding
description:
  PFAM: Flagella basal body rod protein; Domain of unknown function (DUF1078); Flagellar basal body protein FlaE; TIGRFAM: fagellar hook-basal body proteins.


ensembl_gene_id: DespoDRAFT_02853
symbol: EIM64671.1
gene_biotype: protein_coding
description:
  Flagellar hook-associated protein FlgK; PFAM: Domain of unknown function (DUF1078); TIGRFAM: flagellar hook-associated protein FlgK.


ensembl_gene_id: DespoDRAFT_02854
symbol: EIM64672.1
gene_biotype: protein_coding
description:
  Flagellar hook-associated protein 3; PFAM: Bacterial flagellin N-terminal helical region; Bacterial flagellin C-terminal helical region; TIGRFAM: flagellar hook-associated protein 3.


ensembl_gene_id: DespoDRAFT_02856
symbol: gatB
gene_biotype: protein_coding
description:
  glutamyl-tRNA(Gln) and/or aspartyl-tRNA(Asn) amidotransferase, B subunit; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily.


ensembl_gene_id: DespoDRAFT_02858
symbol: queA
gene_biotype: protein_coding
description:
  S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).


ensembl_gene_id: DespoDRAFT_02859
symbol: tgt
gene_biotype: protein_coding
description:
  tRNA-guanine transglycosylase, queuosine-34-forming; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of  [...]


ensembl_gene_id: DespoDRAFT_02860
symbol: hypA
gene_biotype: protein_coding
description:
  Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.


ensembl_gene_id: DespoDRAFT_02861
symbol: EIM64679.1
gene_biotype: protein_coding
description:
  Hydrogenase accessory protein HypB; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB.


ensembl_gene_id: DespoDRAFT_02870
symbol: gltX
gene_biotype: protein_coding
description:
  glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.


ensembl_gene_id: DespoDRAFT_02871
symbol: rpmF
gene_biotype: protein_coding
description:
  PFAM: Ribosomal L32p protein family; TIGRFAM: ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family.


ensembl_gene_id: DespoDRAFT_02873
symbol: EIM64691.1
gene_biotype: protein_coding
description:
  PFAM: Ribose/Galactose Isomerase; TIGRFAM: ribose 5-phosphate isomerase B; sugar-phosphate isomerases, RpiB/LacA/LacB family.


ensembl_gene_id: DespoDRAFT_02874
symbol: glyA
gene_biotype: protein_coding
description:
  Glycine/serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.


ensembl_gene_id: DespoDRAFT_02876
symbol: nrdR
gene_biotype: protein_coding
description:
  Transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.


ensembl_gene_id: DespoDRAFT_02877
symbol: EIM64695.1
gene_biotype: protein_coding
description:
  Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.


ensembl_gene_id: DespoDRAFT_02879
symbol: ribBA
gene_biotype: protein_coding
description:
  GTP cyclohydrolase II/3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.


ensembl_gene_id: DespoDRAFT_02880
symbol: ribH
gene_biotype: protein_coding
description:
  6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.


ensembl_gene_id: DespoDRAFT_02881
symbol: nusB
gene_biotype: protein_coding
description:
  Transcription antitermination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.


ensembl_gene_id: DespoDRAFT_02885
symbol: EIM64702.1
gene_biotype: protein_coding
description:
  PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E.


ensembl_gene_id: DespoDRAFT_02888
symbol: rsmI
gene_biotype: protein_coding
description:
  Putative S-adenosylmethionine-dependent methyltransferase, YraL family; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.


ensembl_gene_id: DespoDRAFT_02889
symbol: EIM64706.1
gene_biotype: protein_coding
description:
  Putative endonuclease related to Holliday junction resolvase; PFAM: Uncharacterised protein family UPF0102; TIGRFAM: TIGR00252 family protein; Belongs to the UPF0102 family.


ensembl_gene_id: DespoDRAFT_02891
symbol: rplS
gene_biotype: protein_coding
description:
  Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.


ensembl_gene_id: DespoDRAFT_02893
symbol: trmD
gene_biotype: protein_coding
description:
  tRNA (guanine-N1)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.


ensembl_gene_id: DespoDRAFT_02894
symbol: rimM
gene_biotype: protein_coding
description:
  16S rRNA processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family.


ensembl_gene_id: DespoDRAFT_02896
symbol: rpsP
gene_biotype: protein_coding
description:
  PFAM: Ribosomal protein S16; TIGRFAM: ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family.


ensembl_gene_id: DespoDRAFT_02897
symbol: ffh
gene_biotype: protein_coding
description:
  Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual componen [...]


ensembl_gene_id: DespoDRAFT_02898
symbol: rlmN
gene_biotype: protein_coding
description:
  23S rRNA m2A2503 methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family.


ensembl_gene_id: DespoDRAFT_02901
symbol: EIM64718.1
gene_biotype: protein_coding
description:
  Putative tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase with PP-loop ATPase domain; PFAM: Thiamine biosynthesis protein (ThiI).


ensembl_gene_id: DespoDRAFT_02908
symbol: EIM64725.1
gene_biotype: protein_coding
description:
  PFAM: Malic enzyme, NAD binding domain; Phosphate acetyl/butaryl transferase; Malic enzyme, N-terminal domain; TIGRFAM: phosphate acetyltransferase.


ensembl_gene_id: DespoDRAFT_02910
symbol: EIM64727.1
gene_biotype: protein_coding
description:
  PFAM: domain; FAD binding domain; TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit, Bacillus subtilis subgroup.


ensembl_gene_id: DespoDRAFT_02911
symbol: EIM64728.1
gene_biotype: protein_coding
description:
  Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein.


ensembl_gene_id: DespoDRAFT_02921
symbol: EIM64738.1
gene_biotype: protein_coding
description:
  PFAM: Sodium:solute symporter family; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: DespoDRAFT_02935
symbol: sucD
gene_biotype: protein_coding
description:
  succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.


ensembl_gene_id: DespoDRAFT_02936
symbol: sucC
gene_biotype: protein_coding
description:
  succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.


ensembl_gene_id: DespoDRAFT_02942
symbol: EIM64759.1
gene_biotype: protein_coding
description:
  PFAM: CRISPR-associated protein (Cas_Cas2CT1978); TIGRFAM: CRISPR-associated endoribonuclease Cas2, subtype I-E/ECOLI.


ensembl_gene_id: DespoDRAFT_02944
symbol: EIM64761.1
gene_biotype: protein_coding
description:
  PFAM: CRISPR-associated protein (Cas_Cas5); TIGRFAM: CRISPR-associated protein Cas5/CasD, subtype I-E/ECOLI; CRISPR-associated protein Cas5, N-terminal domain.


ensembl_gene_id: DespoDRAFT_02946
symbol: EIM64763.1
gene_biotype: protein_coding
description:
  PFAM: CRISPR associated protein; TIGRFAM: CRISPR-associated protein Cas6/Cse3/CasE, subtype I-E/ECOLI.


ensembl_gene_id: DespoDRAFT_02947
symbol: EIM64764.1
gene_biotype: protein_coding
description:
  CRISPR type I-E protein CasB; PFAM: CRISPR-associated protein Cse2 (CRISPR_cse2); TIGRFAM: CRISPR type I-E/ECOLI-associated protein CasB/Cse2.


ensembl_gene_id: DespoDRAFT_02948
symbol: EIM64765.1
gene_biotype: protein_coding
description:
  CRISPR type I-E protein CasA; PFAM: CRISPR-associated protein Cse1 (CRISPR_cse1); TIGRFAM: CRISPR type I-E/ECOLI-associated protein CasA/Cse1.


ensembl_gene_id: DespoDRAFT_02949
symbol: EIM64766.1
gene_biotype: protein_coding
description:
  PFAM: DEAD/DEAH box helicase; TIGRFAM: CRISPR-associated helicase Cas3; CRISPR-associated endonuclease Cas3-HD.


ensembl_gene_id: DespoDRAFT_02952
symbol: EIM64769.1
gene_biotype: protein_coding
description:
  PFAM: Aldehyde dehydrogenase family; TIGRFAM: succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: DespoDRAFT_02955
symbol: EIM64772.1
gene_biotype: protein_coding
description:
  Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; TIGRFAM: erythrose-4-phosphate dehydrogenase; glyceraldehyde-3-phosphate dehydrogenase, type I; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.


ensembl_gene_id: DespoDRAFT_02956
symbol: fhs
gene_biotype: protein_coding
description:
  Formyltetrahydrofolate synthetase; PFAM: Formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family.


ensembl_gene_id: DespoDRAFT_02957
symbol: folD
gene_biotype: protein_coding
description:
  5,10-methylene-tetrahydrofolate dehydrogenase/methenyl tetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.


ensembl_gene_id: DespoDRAFT_02959
symbol: ispE
gene_biotype: protein_coding
description:
  4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.


ensembl_gene_id: DespoDRAFT_02961
symbol: prs
gene_biotype: protein_coding
description:
  Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.


ensembl_gene_id: DespoDRAFT_02962
symbol: rplY
gene_biotype: protein_coding
description:
  Ribosomal protein L25, Ctc-form; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.


ensembl_gene_id: DespoDRAFT_02963
symbol: pth
gene_biotype: protein_coding
description:
  peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.


ensembl_gene_id: DespoDRAFT_02965
symbol: EIM64781.1
gene_biotype: protein_coding
description:
  Pseudouridine synthase, RluA family; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.


ensembl_gene_id: DespoDRAFT_02967
symbol: dtd
gene_biotype: protein_coding
description:
  D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family.


ensembl_gene_id: DespoDRAFT_02968
symbol: EIM64784.1
gene_biotype: protein_coding
description:
  PFAM: PHP domain; TIGRFAM: histidinol phosphate phosphatase, HisJ family; Belongs to the PHP hydrolase family. HisK subfamily.


ensembl_gene_id: DespoDRAFT_02970
symbol: clpB
gene_biotype: protein_coding
description:
  ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.


ensembl_gene_id: DespoDRAFT_02978
symbol: EIM64794.1
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate-protein phosphotransferase; PFAM: GAF domain; PEP-utilising enzyme, mobile domain; PEP-utilising enzyme, TIM barrel domain; PEP-utilising enzyme, N-terminal; TIGRFAM: phosphoenolpyruvate-protein phosphotransferase; Belongs to the PEP-utilizing enzyme family.


ensembl_gene_id: DespoDRAFT_02987
symbol: EIM64801.1
gene_biotype: protein_coding
description:
  Response regulator containing a CheY-like receiver domain and an HD-GYP domain; PFAM: HD domain; CHASE2 domain.


ensembl_gene_id: DespoDRAFT_03003
symbol: EIM64815.1
gene_biotype: protein_coding
description:
  Pyruvate/oxaloacetate carboxyltransferase; PFAM: HMGL-like; Biotin-requiring enzyme; Conserved carboxylase domain.


ensembl_gene_id: DespoDRAFT_03007
symbol: gpmI
gene_biotype: protein_coding
description:
  2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.


ensembl_gene_id: DespoDRAFT_03008
symbol: rsfS
gene_biotype: protein_coding
description:
  Iojap-like ribosome-associated protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.


ensembl_gene_id: DespoDRAFT_03009
symbol: nadD
gene_biotype: protein_coding
description:
  Nicotinate/nicotinamide nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).


ensembl_gene_id: DespoDRAFT_03010
symbol: obg
gene_biotype: protein_coding
description:
  Obg family GTPase CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.


ensembl_gene_id: DespoDRAFT_03011
symbol: rpmA
gene_biotype: protein_coding
description:
  PFAM: Ribosomal L27 protein; TIGRFAM: ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family.


ensembl_gene_id: DespoDRAFT_03012
symbol: rplU
gene_biotype: protein_coding
description:
  Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.


ensembl_gene_id: DespoDRAFT_03021
symbol: EIM64832.1
gene_biotype: protein_coding
description:
  Lipid A 3-O-deacylase (PagL); Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety; Belongs to the PagL family.


ensembl_gene_id: DespoDRAFT_03025
symbol: EIM64835.1
gene_biotype: protein_coding
description:
  Folylpolyglutamate synthase/dihydrofolate synthase; PFAM: Mur ligase family, glutamate ligase domain; Mur ligase middle domain; TIGRFAM: folylpolyglutamate synthase/dihydrofolate synthase; Belongs to the folylpolyglutamate synthase family.


ensembl_gene_id: DespoDRAFT_03026
symbol: rpsU
gene_biotype: protein_coding
description:
  PFAM: Ribosomal protein S21; TIGRFAM: ribosomal protein S21; manually curated; Belongs to the bacterial ribosomal protein bS21 family.


ensembl_gene_id: DespoDRAFT_03027
symbol: adk
gene_biotype: protein_coding
description:
  Adenylate kinase family protein; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.


ensembl_gene_id: DespoDRAFT_03029
symbol: eno
gene_biotype: protein_coding
description:
  Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.


ensembl_gene_id: DespoDRAFT_03030
symbol: pyrG
gene_biotype: protein_coding
description:
  CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.


ensembl_gene_id: DespoDRAFT_03032
symbol: EIM64842.1
gene_biotype: protein_coding
description:
  N-methylhydantoinase B/acetone carboxylase, alpha subunit; PFAM: Hydantoinase/oxoprolinase; Hydantoinase B/oxoprolinase; Hydantoinase/oxoprolinase N-terminal region.


ensembl_gene_id: DespoDRAFT_03033
symbol: EIM64843.1
gene_biotype: protein_coding
description:
  PFAM: Uncharacterised protein family UPF0066; TIGRFAM: putative methyltransferase, YaeB/AF_0241 family.


ensembl_gene_id: DespoDRAFT_03035
symbol: EIM64845.1
gene_biotype: protein_coding
description:
  3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase; PFAM: KR domain; FabA-like domain; manually curated.


ensembl_gene_id: DespoDRAFT_03036
symbol: EIM64846.1
gene_biotype: protein_coding
description:
  Polyketide synthase family protein; PFAM: Acyl transferase domain; Phosphopantetheine attachment site; Beta-ketoacyl synthase, N-terminal domain; Beta-ketoacyl synthase, C-terminal domain; TIGRFAM: polyketide-type polyunsaturated fatty acid synthase PfaA.


ensembl_gene_id: DespoDRAFT_03039
symbol: EIM64849.1
gene_biotype: protein_coding
description:
  ABC-type nitrate/sulfonate/bicarbonate transport system, permease component; PFAM: Binding-protein-dependent transport system inner membrane component; manually curated.


ensembl_gene_id: DespoDRAFT_03054
symbol: EIM64863.1
gene_biotype: protein_coding
description:
  Putative glycosyltransferase; PFAM: Glycosyl transferase family 2; overlaps another CDS with the same product name.


ensembl_gene_id: DespoDRAFT_03064
symbol: EIM64872.1
gene_biotype: protein_coding
description:
  Transposase, IS605 OrfB family, central region; PFAM: Putative transposase DNA-binding domain; Probable transposase; TIGRFAM: transposase, IS605 OrfB family, central region.


ensembl_gene_id: DespoDRAFT_03076
symbol: fcl
gene_biotype: protein_coding
description:
  Nucleoside-diphosphate-sugar epimerase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.


ensembl_gene_id: DespoDRAFT_03089
symbol: vapC
gene_biotype: protein_coding
description:
  Putative nucleic acid-binding protein; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family.


ensembl_gene_id: DespoDRAFT_03097
symbol: EIM64899.1
gene_biotype: protein_coding
description:
  dTDP-glucose 4,6-dehydratase; PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: dTDP-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.


ensembl_gene_id: DespoDRAFT_03126
symbol: EIM64920.1
gene_biotype: protein_coding
description:
  D-heptose-7- phosphate 1-kinase; PFAM: pfkB family carbohydrate kinase; TIGRFAM: rfaE bifunctional protein, domain I.


ensembl_gene_id: DespoDRAFT_03129
symbol: purM
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazole synthetase; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: phosphoribosylaminoimidazole synthetase.


ensembl_gene_id: DespoDRAFT_03130
symbol: tsaD
gene_biotype: protein_coding
description:
  Putative glycoprotease GCP; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.


ensembl_gene_id: DespoDRAFT_03136
symbol: EIM64930.1
gene_biotype: protein_coding
description:
  Uncharacterized protein, possibly involved in aromatic compounds catabolism; PFAM: Thioesterase superfamily; TIGRFAM: uncharacterized domain 1.


ensembl_gene_id: DespoDRAFT_03137
symbol: aroK
gene_biotype: protein_coding
description:
  Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.


ensembl_gene_id: DespoDRAFT_03138
symbol: aroA
gene_biotype: protein_coding
description:
  3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.


ensembl_gene_id: DespoDRAFT_03139
symbol: aroE
gene_biotype: protein_coding
description:
  Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).


ensembl_gene_id: DespoDRAFT_03140
symbol: EIM64934.1
gene_biotype: protein_coding
description:
  PFAM: Prephenate dehydratase; Chorismate mutase type II; TIGRFAM: monofunctional chorismate mutase, high GC gram positive type.


ensembl_gene_id: DespoDRAFT_03141
symbol: EIM64935.1
gene_biotype: protein_coding
description:
  PFAM: 4'-phosphopantetheinyl transferase superfamily; TIGRFAM: phosphopantetheine--protein transferase domain; Belongs to the P-Pant transferase superfamily.


ensembl_gene_id: DespoDRAFT_03144
symbol: ispH
gene_biotype: protein_coding
description:
  (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.


ensembl_gene_id: DespoDRAFT_03145
symbol: EIM64938.1
gene_biotype: protein_coding
description:
  ParB-like partition protein; PFAM: Helix-turn-helix; ParB-like nuclease domain; TIGRFAM: ParB-like partition proteins; Belongs to the ParB family.


ensembl_gene_id: DespoDRAFT_03147
symbol: EIM64940.1
gene_biotype: protein_coding
description:
  ATP-dependent helicase HrpA; PFAM: Helicase conserved C-terminal domain; Helicase associated domain (HA2); Domain of unknown function (DUF3418); DEAD/DEAH box helicase; Domain of unknown function (DUF1605); TIGRFAM: ATP-dependent helicase HrpA.


ensembl_gene_id: DespoDRAFT_03158
symbol: EIM64948.1
gene_biotype: protein_coding
description:
  Peptidase T-like protein; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain; TIGRFAM: peptidase T-like protein.


ensembl_gene_id: DespoDRAFT_03159
symbol: EIM64949.1
gene_biotype: protein_coding
description:
  TIGR00299 family protein; PFAM: Protein of unknown function DUF111; TIGRFAM: TIGR00299 family protein; Belongs to the LarC family.


ensembl_gene_id: DespoDRAFT_03160
symbol: EIM64950.1
gene_biotype: protein_coding
description:
  Phosphatidylglycerophosphatase A-like protein; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).


ensembl_gene_id: DespoDRAFT_03161
symbol: recA
gene_biotype: protein_coding
description:
  Protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.


ensembl_gene_id: DespoDRAFT_03162
symbol: alaS
gene_biotype: protein_coding
description:
  alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.


ensembl_gene_id: DespoDRAFT_03163
symbol: EIM64953.1
gene_biotype: protein_coding
description:
  ABC-type uncharacterized transport system, permease component; PFAM: Binding-protein-dependent transport system inner membrane component.


ensembl_gene_id: DespoDRAFT_03167
symbol: EIM64956.1
gene_biotype: protein_coding
description:
  Long-chain fatty acid transport protein; PFAM: Outer membrane protein transport protein (OMPP1/FadL/TodX).


ensembl_gene_id: DespoDRAFT_03178
symbol: EIM64965.1
gene_biotype: protein_coding
description:
  PFAM: GAF domain; Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.


ensembl_gene_id: DespoDRAFT_03179
symbol: EIM64966.1
gene_biotype: protein_coding
description:
  Arsenite efflux pump ACR3-like permease; PFAM: Universal stress protein family; Sodium Bile acid symporter family.


ensembl_gene_id: DespoDRAFT_03190
symbol: EIM64977.1
gene_biotype: protein_coding
description:
  Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB; PFAM: 2-hydroxyglutaryl-CoA dehydratase, D-component.


ensembl_gene_id: DespoDRAFT_03197
symbol: EIM64984.1
gene_biotype: protein_coding
description:
  PAS domain S-box; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; Bacterial extracellular solute-binding proteins, family 3; TIGRFAM: PAS domain S-box.


ensembl_gene_id: DespoDRAFT_03199
symbol: EIM64986.1
gene_biotype: protein_coding
description:
  PFAM: D-alanyl-D-alanine carboxypeptidase; Penicillin-binding protein 5, C-terminal domain; Belongs to the peptidase S11 family.


ensembl_gene_id: DespoDRAFT_03203
symbol: EIM64990.1
gene_biotype: protein_coding
description:
  ATP-grasp enzyme, D-alanine-D-alanine ligase; PFAM: D-ala D-ala ligase C-terminus; overlaps another CDS with the same product name.


ensembl_gene_id: DespoDRAFT_03205
symbol: EIM64992.1
gene_biotype: protein_coding
description:
  KamA family protein; PFAM: Lysine-2,3-aminomutase; Radical SAM superfamily; TIGRFAM: KamA family protein.


ensembl_gene_id: DespoDRAFT_03207
symbol: EIM64994.1
gene_biotype: protein_coding
description:
  ATPase involved in chromosome partitioning; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.


ensembl_gene_id: DespoDRAFT_03226
symbol: EIM65007.1
gene_biotype: protein_coding
description:
  Site-specific recombinase, DNA invertase Pin; PFAM: Resolvase, N terminal domain; Helix-turn-helix domain of resolvase.


ensembl_gene_id: DespoDRAFT_03231
symbol: EIM65012.1
gene_biotype: protein_coding
description:
  PAS domain S-box; PFAM: Bacterial regulatory proteins, luxR family; PAS fold; TIGRFAM: PAS domain S-box.


ensembl_gene_id: DespoDRAFT_03241
symbol: EIM65021.1
gene_biotype: protein_coding
description:
  Uncharacterized protein involved in cysteine biosynthesis; PFAM: Etoposide-induced protein 2.4 (EI24).


ensembl_gene_id: DespoDRAFT_03244
symbol: EIM65024.1
gene_biotype: protein_coding
description:
  Polyferredoxin, heterodixulfide reductase subunit A; PFAM: Pyridine nucleotide-disulphide oxidoreductase.


ensembl_gene_id: DespoDRAFT_03247
symbol: EIM65027.1
gene_biotype: protein_coding
description:
  PFAM: Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.


ensembl_gene_id: DespoDRAFT_03250
symbol: EIM65030.1
gene_biotype: protein_coding
description:
  Zn-dependent hydrolase, glyoxylase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.


ensembl_gene_id: DespoDRAFT_03251
symbol: speH
gene_biotype: protein_coding
description:
  S-adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.


ensembl_gene_id: DespoDRAFT_03252
symbol: speE-2
gene_biotype: protein_coding
description:
  Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.


ensembl_gene_id: DespoDRAFT_03259
symbol: dnaG
gene_biotype: protein_coding
description:
  DNA primase, catalytic core; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.


ensembl_gene_id: DespoDRAFT_03260
symbol: rpoD
gene_biotype: protein_coding
description:
  RNA polymerase sigma factor, sigma-70 family; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.


ensembl_gene_id: DespoDRAFT_03262
symbol: EIM65041.1
gene_biotype: protein_coding
description:
  PFAM: NIF3 (NGG1p interacting factor 3); TIGRFAM: dinuclear metal center protein, YbgI/SA1388 family.


ensembl_gene_id: DespoDRAFT_03266
symbol: ispD
gene_biotype: protein_coding
description:
  2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).


ensembl_gene_id: DespoDRAFT_03272
symbol: EIM65050.1
gene_biotype: protein_coding
description:
  Putative Ser protein kinase; PFAM: Archaeal ATPase; PrkA AAA domain; PrkA serine protein kinase C-terminal domain.


ensembl_gene_id: DespoDRAFT_03276
symbol: miaB
gene_biotype: protein_coding
description:
  tRNA-N(6)-(isopentenyl)adenosine-37 thiotransferase enzyme MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.


ensembl_gene_id: DespoDRAFT_03277
symbol: map
gene_biotype: protein_coding
description:
  Methionine aminopeptidase, type I; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.


ensembl_gene_id: DespoDRAFT_03279
symbol: nifH
gene_biotype: protein_coding
description:
  Nitrogenase iron protein; The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein; Belongs to the NifH/BchL/ChlL family.


ensembl_gene_id: DespoDRAFT_03280
symbol: EIM65058.1
gene_biotype: protein_coding
description:
  Nitrogenase molybdenum-iron protein alpha chain; PFAM: Nitrogenase component 1 type Oxidoreductase; TIGRFAM: nitrogenase component I, alpha chain; nitrogenase molybdenum-iron protein alpha chain.


ensembl_gene_id: DespoDRAFT_03281
symbol: EIM65059.1
gene_biotype: protein_coding
description:
  Nitrogenase molybdenum-iron protein beta chain; This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation; Belongs to the NifD/NifK/NifE/NifN family.


ensembl_gene_id: DespoDRAFT_03282
symbol: EIM65060.1
gene_biotype: protein_coding
description:
  PFAM: Nitrogenase component 1 type Oxidoreductase; TIGRFAM: nitrogenase molybdenum-iron cofactor biosynthesis protein NifE; Belongs to the NifD/NifK/NifE/NifN family.


ensembl_gene_id: DespoDRAFT_03283
symbol: EIM65061.1
gene_biotype: protein_coding
description:
  Nitrogenase molybdenum-iron protein, alpha and beta chains; PFAM: Nitrogenase component 1 type Oxidoreductase; Belongs to the NifD/NifK/NifE/NifN family.


ensembl_gene_id: DespoDRAFT_03284
symbol: EIM65062.1
gene_biotype: protein_coding
description:
  Nitrogenase cofactor biosynthesis protein NifB; PFAM: Radical SAM superfamily; Dinitrogenase iron-molybdenum cofactor; TIGRFAM: nitrogenase cofactor biosynthesis protein NifB.


ensembl_gene_id: DespoDRAFT_03286
symbol: EIM65064.1
gene_biotype: protein_coding
description:
  PFAM: HMGL-like; TIGRFAM: homocitrate synthase NifV; Belongs to the alpha-IPM synthase/homocitrate synthase family.


ensembl_gene_id: DespoDRAFT_03297
symbol: birA
gene_biotype: protein_coding
description:
  birA, biotin-(acetyl-CoA-carboxylase) ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.


ensembl_gene_id: DespoDRAFT_03359
symbol: EIM65129.1
gene_biotype: protein_coding
description:
  PFAM: Bacterial sugar transferase; TIGRFAM: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase.


ensembl_gene_id: DespoDRAFT_03366
symbol: EIM65135.1
gene_biotype: protein_coding
description:
  PFAM: Chain length determinant protein; CobQ/CobB/MinD/ParA nucleotide binding domain; TIGRFAM: capsular exopolysaccharide family.


ensembl_gene_id: DespoDRAFT_03373
symbol: EIM65142.1
gene_biotype: protein_coding
description:
  PFAM: Pyridoxal-dependent decarboxylase conserved domain; TIGRFAM: putative pyridoxal-dependent aspartate 1-decarboxylase.


ensembl_gene_id: DespoDRAFT_03376
symbol: EIM65145.1
gene_biotype: protein_coding
description:
  Arginine kinase; PFAM: ATP:guanido phosphotransferase, N-terminal domain; ATP:guanido phosphotransferase, C-terminal catalytic domain; Belongs to the ATP:guanido phosphotransferase family.


ensembl_gene_id: DespoDRAFT_03384
symbol: gpsA
gene_biotype: protein_coding
description:
  PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; TIGRFAM: glycerol-3-phosphate dehydrogenase (NAD(+)); Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.


ensembl_gene_id: DespoDRAFT_03388
symbol: EIM65157.1
gene_biotype: protein_coding
description:
  ABC-type transport system involved in resistance to organic solvents, auxiliary component; PFAM: Toluene tolerance, Ttg2.


ensembl_gene_id: DespoDRAFT_03390
symbol: EIM65159.1
gene_biotype: protein_coding
description:
  Phosphate ABC transporter, permease protein PstA; PFAM: Binding-protein-dependent transport system inner membrane component; Domain of unknown function (DUF3333); TIGRFAM: phosphate ABC transporter, permease protein PstA.


ensembl_gene_id: DespoDRAFT_03394
symbol: EIM65163.1
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease III; PFAM: Endonuclease/Exonuclease/phosphatase family; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III (xth).


ensembl_gene_id: DespoDRAFT_03395
symbol: EIM65164.1
gene_biotype: protein_coding
description:
  Ferredoxin-thioredoxin reductase, catalytic subunit; PFAM: Ferredoxin thioredoxin reductase catalytic beta chain.


ensembl_gene_id: DespoDRAFT_03398
symbol: EIM65167.1
gene_biotype: protein_coding
description:
  PFAM: Desulfoferrodoxin, N-terminal domain; Desulfoferrodoxin; TIGRFAM: desulfoferrodoxin FeS4 iron-binding domain; desulfoferrodoxin; desulfoferrodoxin ferrous iron-binding domain.


ensembl_gene_id: DespoDRAFT_03399
symbol: EIM65168.1
gene_biotype: protein_coding
description:
  TIGR01777 family protein; PFAM: NAD dependent epimerase/dehydratase family; Domain of unknown function (DUF1731); TIGRFAM: TIGR01777 family protein.


ensembl_gene_id: DespoDRAFT_03406
symbol: EIM65175.1
gene_biotype: protein_coding
description:
  5''-deoxy-5''-methylthioadenosine phosphorylase; Purine nucleoside phosphorylase involved in purine salvage.


ensembl_gene_id: DespoDRAFT_03407
symbol: apt
gene_biotype: protein_coding
description:
  Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.


ensembl_gene_id: DespoDRAFT_03409
symbol: recC
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease V, gamma subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and r [...]


ensembl_gene_id: DespoDRAFT_03410
symbol: recB
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease V, beta subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and re [...]


ensembl_gene_id: DespoDRAFT_03423
symbol: tdh
gene_biotype: protein_coding
description:
  L-threonine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family.


ensembl_gene_id: DespoDRAFT_03425
symbol: selO
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation). Belongs to the SELO family.


ensembl_gene_id: DespoDRAFT_03430
symbol: EIM65197.1
gene_biotype: protein_coding
description:
  ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component; PFAM: Response regulator receiver domain.


ensembl_gene_id: DespoDRAFT_03432
symbol: EIM65199.1
gene_biotype: protein_coding
description:
  ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component; PFAM: NMT1/THI5 like; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence.


ensembl_gene_id: DespoDRAFT_03436
symbol: EIM65203.1
gene_biotype: protein_coding
description:
  Hypothetical protein; PFAM: Poly(hydroxyalcanoate) granule associated protein (phasin); Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E).


ensembl_gene_id: DespoDRAFT_03443
symbol: EIM65210.1
gene_biotype: protein_coding
description:
  HipA domain-containing protein; PFAM: HipA-like C-terminal domain; HipA-like N-terminal domain; TIGRFAM: HipA N-terminal domain.


ensembl_gene_id: DespoDRAFT_03447
symbol: EIM65214.1
gene_biotype: protein_coding
description:
  Zn-dependent oxidoreductase, NADPH:quinone reductase; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase.


ensembl_gene_id: DespoDRAFT_03463
symbol: EIM65227.1
gene_biotype: protein_coding
description:
  dTDP-4-dehydrorhamnose 3,5-epimerase-like enzyme; PFAM: dTDP-4-dehydrorhamnose 3,5-epimerase; TIGRFAM: dTDP-4-dehydrorhamnose 3,5-epimerase.


ensembl_gene_id: DespoDRAFT_03468
symbol: EIM65230.1
gene_biotype: protein_coding
description:
  DnaJ-class molecular chaperone with C-terminal Zn finger domain; PFAM: DnaJ domain; Protein of unknown function (DUF1232).


ensembl_gene_id: DespoDRAFT_03469
symbol: EIM65231.1
gene_biotype: protein_coding
description:
  PFAM: Dihydrodipicolinate reductase, N-terminus; Dihydrodipicolinate reductase, C-terminus; TIGRFAM: dihydrodipicolinate reductase; Belongs to the DapB family.


ensembl_gene_id: DespoDRAFT_03470
symbol: EIM65232.1
gene_biotype: protein_coding
description:
  Nucleoside-diphosphate-sugar pyrophosphorylase family protein; PFAM: Nucleotidyl transferase; Phosphotransferase enzyme family.


ensembl_gene_id: DespoDRAFT_03471
symbol: EIM65233.1
gene_biotype: protein_coding
description:
  PFAM: Acyltransferase; TIGRFAM: glycerol-3-phosphate O-acyltransferase; Belongs to the GPAT/DAPAT family.


ensembl_gene_id: DespoDRAFT_03474
symbol: hisC
gene_biotype: protein_coding
description:
  PFAM: Aminotransferase class I and II; TIGRFAM: histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.


ensembl_gene_id: DespoDRAFT_03476
symbol: EIM65238.1
gene_biotype: protein_coding
description:
  Ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.


ensembl_gene_id: DespoDRAFT_03479
symbol: pfkA-2
gene_biotype: protein_coding
description:
  6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.


ensembl_gene_id: DespoDRAFT_03480
symbol: guaB
gene_biotype: protein_coding
description:
  Inosine-5''-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.


ensembl_gene_id: DespoDRAFT_03481
symbol: EIM65243.1
gene_biotype: protein_coding
description:
  PFAM: PHP domain; Bacterial DNA polymerase III alpha subunit; TIGRFAM: DNA-directed DNA polymerase III (polc).


ensembl_gene_id: DespoDRAFT_03486
symbol: valS
gene_biotype: protein_coding
description:
  valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.


ensembl_gene_id: DespoDRAFT_03487
symbol: EIM65249.1
gene_biotype: protein_coding
description:
  Nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase, C-terminal domain; Quinolinate phosphoribosyl transferase, N-terminal domain; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family.


ensembl_gene_id: DespoDRAFT_03493
symbol: EIM65254.1
gene_biotype: protein_coding
description:
  PFAM: Response regulator receiver domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.


ensembl_gene_id: DespoDRAFT_03494
symbol: lepA
gene_biotype: protein_coding
description:
  GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.


ensembl_gene_id: DespoDRAFT_03495
symbol: EIM65256.1
gene_biotype: protein_coding
description:
  PFAM: HMGL-like; LeuA allosteric (dimerisation) domain; TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein; Belongs to the alpha-IPM synthase/homocitrate synthase family.


ensembl_gene_id: DespoDRAFT_03496
symbol: EIM65257.1
gene_biotype: protein_coding
description:
  PFAM: ACT domain; Small subunit of acetolactate synthase; TIGRFAM: acetolactate synthase, small subunit.


ensembl_gene_id: DespoDRAFT_03497
symbol: EIM65258.1
gene_biotype: protein_coding
description:
  Acetolactate synthase, large subunit, biosynthetic type; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: acetolactate synthase, large subunit, biosynthetic type.


ensembl_gene_id: DespoDRAFT_03508
symbol: cmoA
gene_biotype: protein_coding
description:
  Methyltransferase, putative; Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).


ensembl_gene_id: DespoDRAFT_03509
symbol: cmoB
gene_biotype: protein_coding
description:
  Protein of unknown function (DUF1698); Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L- methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5- carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.


ensembl_gene_id: DespoDRAFT_03512
symbol: EIM65271.1
gene_biotype: protein_coding
description:
  Helicase family protein with metal-binding cysteine cluster; PFAM: Helicase conserved C-terminal domain; Domain of unknown function (DUF1998); DEAD/DEAH box helicase.


ensembl_gene_id: DespoDRAFT_03516
symbol: EIM65274.1
gene_biotype: protein_coding
description:
  dGTP triphosphohydrolase; PFAM: HD domain; TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase, putative; Belongs to the dGTPase family. Type 2 subfamily.


ensembl_gene_id: DespoDRAFT_03520
symbol: EIM65278.1
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.


ensembl_gene_id: DespoDRAFT_03524
symbol: EIM65282.1
gene_biotype: protein_coding
description:
  Translation elongation factor-like GTPase; PFAM: Elongation factor Tu domain 2; Elongation factor G C-terminus; Elongation factor Tu GTP binding domain; Elongation factor G, domain IV; TIGRFAM: translation elongation factor EF-G; small GTP-binding protein domain.


ensembl_gene_id: DespoDRAFT_03526
symbol: dxs
gene_biotype: protein_coding
description:
  1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.


ensembl_gene_id: DespoDRAFT_03528
symbol: xseB
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease VII, small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.


ensembl_gene_id: DespoDRAFT_03529
symbol: xseA
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease VII, large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family.


ensembl_gene_id: DespoDRAFT_03532
symbol: EIM65290.1
gene_biotype: protein_coding
description:
  PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: pyridine nucleotide-disulfide oxidoreductase family protein.


ensembl_gene_id: DespoDRAFT_03537
symbol: EIM65294.1
gene_biotype: protein_coding
description:
  PFAM: Y_Y_Y domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Two component regulator propeller; His Kinase A (phosphoacceptor) domain.


ensembl_gene_id: DespoDRAFT_03544
symbol: proA
gene_biotype: protein_coding
description:
  Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.


ensembl_gene_id: DespoDRAFT_03545
symbol: proB
gene_biotype: protein_coding
description:
  Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.


ensembl_gene_id: DespoDRAFT_03552
symbol: EIM65308.1
gene_biotype: protein_coding
description:
  Psp operon transcriptional activator PspF; PFAM: Bacterial regulatory protein, Fis family; Sigma-54 interaction domain; TIGRFAM: psp operon transcriptional activator PspF.


ensembl_gene_id: DespoDRAFT_03555
symbol: EIM65311.1
gene_biotype: protein_coding
description:
  Putative redox protein, regulator of disulfide bond formation; PFAM: SirA-like protein; Belongs to the sulfur carrier protein TusA family.


ensembl_gene_id: DespoDRAFT_03569
symbol: EIM65325.1
gene_biotype: protein_coding
description:
  Putative peptidoglycan-binding domain-containing protein; PFAM: Putative peptidoglycan binding domain.


ensembl_gene_id: DespoDRAFT_03571
symbol: menD
gene_biotype: protein_coding
description:
  2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily.


ensembl_gene_id: DespoDRAFT_03572
symbol: menB
gene_biotype: protein_coding
description:
  Dihydroxynaphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA).


ensembl_gene_id: DespoDRAFT_03573
symbol: EIM65329.1
gene_biotype: protein_coding
description:
  Enolase superfamily enzyme related to L-alanine-DL-glutamate epimerase; PFAM: Mandelate racemase / muconate lactonizing enzyme, C-terminal domain; TIGRFAM: o-succinylbenzoate synthase.


ensembl_gene_id: DespoDRAFT_03576
symbol: EIM65332.1
gene_biotype: protein_coding
description:
  Indolepyruvate ferredoxin oxidoreductase, alpha subunit; Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.


ensembl_gene_id: DespoDRAFT_03577
symbol: EIM65333.1
gene_biotype: protein_coding
description:
  2-oxoacid:ferredoxin oxidoreductase, gamma subunit; PFAM: Pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: indolepyruvate ferredoxin oxidoreductase, beta subunit.


ensembl_gene_id: DespoDRAFT_03578
symbol: aroQ
gene_biotype: protein_coding
description:
  3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.


ensembl_gene_id: DespoDRAFT_03596
symbol: trpB-2
gene_biotype: protein_coding
description:
  Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.


ensembl_gene_id: DespoDRAFT_03597
symbol: trpA
gene_biotype: protein_coding
description:
  Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.


ensembl_gene_id: DespoDRAFT_03598
symbol: mtnA
gene_biotype: protein_coding
description:
  S-methyl-5-thioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).


ensembl_gene_id: DespoDRAFT_03602
symbol: EIM65353.1
gene_biotype: protein_coding
description:
  ABC-type metal ion transport system, periplasmic component/surface adhesin; PFAM: Periplasmic solute binding protein family.


ensembl_gene_id: DespoDRAFT_03603
symbol: EIM65354.1
gene_biotype: protein_coding
description:
  ATPase component of Mn/Zn ABC-type transporter; PFAM: ABC transporter; manually curated; non-canonical start codon.


ensembl_gene_id: DespoDRAFT_03608
symbol: EIM65359.1
gene_biotype: protein_coding
description:
  Ferrous iron transporter FeoB; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.


ensembl_gene_id: DespoDRAFT_03625
symbol: thiM
gene_biotype: protein_coding
description:
  Hydroxyethylthiazole kinase, sugar kinase family; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family.


ensembl_gene_id: DespoDRAFT_03631
symbol: thiE
gene_biotype: protein_coding
description:
  Thiamine monophosphate synthase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.


ensembl_gene_id: DespoDRAFT_03636
symbol: EIM65379.1
gene_biotype: protein_coding
description:
  Uncharacterized protein, possibly involved in aromatic compounds catabolism; PFAM: Thioesterase superfamily; TIGRFAM: uncharacterized domain 1; phenylacetic acid degradation protein PaaD.


ensembl_gene_id: DespoDRAFT_03637
symbol: EIM65380.1
gene_biotype: protein_coding
description:
  PFAM: Histidine biosynthesis protein; TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase, eukaryotic type; Belongs to the HisA/HisF family.


ensembl_gene_id: DespoDRAFT_03638
symbol: EIM65381.1
gene_biotype: protein_coding
description:
  ABC-type uncharacterized transport system, auxiliary component; PFAM: Protein of unknown function (DUF330).


ensembl_gene_id: DespoDRAFT_03639
symbol: EIM65382.1
gene_biotype: protein_coding
description:
  ABC-type transport system involved in resistance to organic solvents, periplasmic component; PFAM: mce related protein.


ensembl_gene_id: DespoDRAFT_03644
symbol: prmA
gene_biotype: protein_coding
description:
  Ribosomal protein L11 methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family.


ensembl_gene_id: DespoDRAFT_03645
symbol: EIM65388.1
gene_biotype: protein_coding
description:
  PFAM: Histidine kinase; HAMP domain; Cache domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.


ensembl_gene_id: DespoDRAFT_03649
symbol: EIM65392.1
gene_biotype: protein_coding
description:
  Mn2+/Fe2_ transporter, NRAMP family; PFAM: Natural resistance-associated macrophage protein; TIGRFAM: NRAMP (natural resistance-associated macrophage protein) metal ion transporters.


ensembl_gene_id: DespoDRAFT_03656
symbol: EIM65399.1
gene_biotype: protein_coding
description:
  PFAM: Phosphatidylserine decarboxylase; TIGRFAM: phosphatidylserine decarboxylase precursor; Belongs to the phosphatidylserine decarboxylase family.


ensembl_gene_id: DespoDRAFT_03673
symbol: EIM65413.1
gene_biotype: protein_coding
description:
  Cysteine desulfurase NifS; Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.


ensembl_gene_id: DespoDRAFT_03674
symbol: EIM65414.1
gene_biotype: protein_coding
description:
  Fe-S cluster assembly protein NifU; PFAM: NifU-like N terminal domain; BFD-like [2Fe-2S] binding domain; TIGRFAM: Fe-S cluster assembly protein NifU.


ensembl_gene_id: DespoDRAFT_03675
symbol: EIM65415.1
gene_biotype: protein_coding
description:
  TIGR02757 family protein; PFAM: Protein of unknown function (DUF2400); TIGRFAM: TIGR02757 family protein.


ensembl_gene_id: DespoDRAFT_03678
symbol: proC
gene_biotype: protein_coding
description:
  Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.


ensembl_gene_id: DespoDRAFT_03681
symbol: aroC
gene_biotype: protein_coding
description:
  Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.


ensembl_gene_id: DespoDRAFT_03683
symbol: EIM65423.1
gene_biotype: protein_coding
description:
  PFAM: Acyl transferase domain; Phosphopantetheine attachment site; KR domain; 2-nitropropane dioxygenase; Beta-ketoacyl synthase, N-terminal domain; Beta-ketoacyl synthase, C-terminal domain; TIGRFAM: malonyl CoA-acyl carrier protein transacylase.


ensembl_gene_id: DespoDRAFT_03684
symbol: EIM65424.1
gene_biotype: protein_coding
description:
  PFAM: 4'-phosphopantetheinyl transferase superfamily; Belongs to the P-Pant transferase superfamily.


ensembl_gene_id: DespoDRAFT_03704
symbol: EIM65443.1
gene_biotype: protein_coding
description:
  Putative phage tail region protein; PFAM: T4-like virus tail tube protein gp19; TIGRFAM: conserved hypothetical phage tail region protein.


ensembl_gene_id: DespoDRAFT_03714
symbol: EIM65453.1
gene_biotype: protein_coding
description:
  PFAM: Bacterial regulatory proteins, crp family; Cyclic nucleotide-binding domain; manually curated; non-canonical start codon.


ensembl_gene_id: DespoDRAFT_03716
symbol: EIM65455.1
gene_biotype: protein_coding
description:
  PFAM: FKBP-type peptidyl-prolyl cis-trans isomerase; Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD.


ensembl_gene_id: DespoDRAFT_03717
symbol: mtgA
gene_biotype: protein_coding
description:
  Monofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family.


ensembl_gene_id: DespoDRAFT_03756
symbol: EIM65491.1
gene_biotype: protein_coding
description:
  PFAM: Prephenate dehydrogenase; Chorismate mutase type II; TIGRFAM: chorismate mutase domain of T-protein.


ensembl_gene_id: DespoDRAFT_03764
symbol: EIM65499.1
gene_biotype: protein_coding
description:
  Thiazole biosynthesis protein ThiH; PFAM: Radical SAM superfamily; Biotin and Thiamin Synthesis associated domain; TIGRFAM: thiazole biosynthesis protein ThiH.


ensembl_gene_id: DespoDRAFT_03765
symbol: thiG
gene_biotype: protein_coding
description:
  Putative enzyme of thiazole biosynthesis; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.


ensembl_gene_id: DespoDRAFT_03767
symbol: dapF
gene_biotype: protein_coding
description:
  Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.


ensembl_gene_id: DespoDRAFT_03769
symbol: thrS
gene_biotype: protein_coding
description:
  threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).


