# geneInfo

ensembl_gene_id: RGE_00010
symbol: dnaA
gene_biotype: protein_coding
description:
  Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.


ensembl_gene_id: RGE_00020
symbol: dnaN
gene_biotype: protein_coding
description:
  DNA polymerase III beta subunit DnaN; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiatio [...]


ensembl_gene_id: RGE_00030
symbol: gyrB
gene_biotype: protein_coding
description:
  DNA gyrase subunit B GyrB; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.


ensembl_gene_id: RGE_00120
symbol: queC
gene_biotype: protein_coding
description:
  7-cyano-7-deazaguanine synthase QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.


ensembl_gene_id: RGE_00150
symbol: RGE_00150
gene_biotype: protein_coding
description:
  Secretion protein HlyD family protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: RGE_00240
symbol: ligT
gene_biotype: protein_coding
description:
  2'-5' RNA ligase LigT; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family.


ensembl_gene_id: RGE_00320
symbol: RGE_00320
gene_biotype: protein_coding
description:
  Putative ABC transporter substrate binding protein; Required for the activity of the bacterial periplasmic transport system of putrescine; Belongs to the bacterial solute-binding protein PotD/PotF family.


ensembl_gene_id: RGE_00560
symbol: gidA
gene_biotype: protein_coding
description:
  tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family.


ensembl_gene_id: RGE_00570
symbol: rsmG
gene_biotype: protein_coding
description:
  Ribosomal RNA small subunit methyltransferase G RsmG; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.


ensembl_gene_id: RGE_00600
symbol: argC
gene_biotype: protein_coding
description:
  N-acetyl-gamma-glutamyl-phosphate reductase ArgC; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 2 subfamily.


ensembl_gene_id: RGE_00680
symbol: aroG
gene_biotype: protein_coding
description:
  3-deoxy-D-arabinoheptulosonate-7-phosphate synthase AroG; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP).


ensembl_gene_id: RGE_00690
symbol: RGE_00690
gene_biotype: protein_coding
description:
  Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.


ensembl_gene_id: RGE_00720
symbol: rsmI
gene_biotype: protein_coding
description:
  Tetrapyrrole methylase family protein; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.


ensembl_gene_id: RGE_00800
symbol: RGE_00800
gene_biotype: protein_coding
description:
  Alanine racemase domain-containing protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.


ensembl_gene_id: RGE_00830
symbol: putA
gene_biotype: protein_coding
description:
  Proline dehydrogenase/delta-1-pyrroline-5-carboxylate dehydrogenase PutA; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: RGE_00920
symbol: prfC
gene_biotype: protein_coding
description:
  Peptide chain release factor RF-3 PrfC; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.


ensembl_gene_id: RGE_00960
symbol: ubiA
gene_biotype: protein_coding
description:
  4-hydroxybenzoate octaprenyltransferase UbiA; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.


ensembl_gene_id: RGE_00970
symbol: proC
gene_biotype: protein_coding
description:
  Pyrroline-5-carboxylate reductase ProC; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.


ensembl_gene_id: RGE_00980
symbol: recG
gene_biotype: protein_coding
description:
  ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily.


ensembl_gene_id: RGE_00990
symbol: queA
gene_biotype: protein_coding
description:
  S-adenosylmethionine:tRNA ribosyltransferase-isomerase QueA; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).


ensembl_gene_id: RGE_01000
symbol: tgt
gene_biotype: protein_coding
description:
  Queuine tRNA-ribosyltransferase Tgt; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to fo [...]


ensembl_gene_id: RGE_01070
symbol: pckG
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate carboxykinase [GTP] PckG; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.


ensembl_gene_id: RGE_01220
symbol: rlpA
gene_biotype: protein_coding
description:
  Rare lipoprotein A RlpA; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.


ensembl_gene_id: RGE_01350
symbol: pntB
gene_biotype: protein_coding
description:
  NAD(P) transhydrogenase, beta subunit PntB; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.


ensembl_gene_id: RGE_01430
symbol: ackA
gene_biotype: protein_coding
description:
  Acetate kinase AckA; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.


ensembl_gene_id: RGE_01580
symbol: purU
gene_biotype: protein_coding
description:
  Formyltetrahydrofolate deformylase PurU; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).


ensembl_gene_id: RGE_01640
symbol: ilvE
gene_biotype: protein_coding
description:
  Branched-chain amino acid aminotransferase IlvE; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: RGE_01670
symbol: radA
gene_biotype: protein_coding
description:
  DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.


ensembl_gene_id: RGE_01690
symbol: alr
gene_biotype: protein_coding
description:
  Alanine racemase Alr; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.


ensembl_gene_id: RGE_01930
symbol: glpK
gene_biotype: protein_coding
description:
  Glycerol kinase GlpK; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.


ensembl_gene_id: RGE_02130
symbol: priA
gene_biotype: protein_coding
description:
  Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.


ensembl_gene_id: RGE_02140
symbol: hemE
gene_biotype: protein_coding
description:
  Uroporphyrinogen decarboxylase HemE; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.


ensembl_gene_id: RGE_02220
symbol: atpC
gene_biotype: protein_coding
description:
  ATP synthase epsilon chain AtpC; Produces ATP from ADP in the presence of a proton gradient across the membrane.


ensembl_gene_id: RGE_02230
symbol: atpD
gene_biotype: protein_coding
description:
  ATP synthase subunit beta AtpD; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.


ensembl_gene_id: RGE_02240
symbol: atpG
gene_biotype: protein_coding
description:
  ATP synthase gamma chain AtpG; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.


ensembl_gene_id: RGE_02250
symbol: atpA
gene_biotype: protein_coding
description:
  ATP synthase subunit alpha AtpA; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.


ensembl_gene_id: RGE_02260
symbol: atpH
gene_biotype: protein_coding
description:
  ATP synthase subunit delta AtpH; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.


ensembl_gene_id: RGE_02270
symbol: atpF
gene_biotype: protein_coding
description:
  ATP synthase subunit b AtpF; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family.


ensembl_gene_id: RGE_02280
symbol: atpE
gene_biotype: protein_coding
description:
  ATP synthase subunit c AtpE; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.


ensembl_gene_id: RGE_02290
symbol: atpB
gene_biotype: protein_coding
description:
  ATP synthase subunit a AtpB; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family.


ensembl_gene_id: RGE_02480
symbol: kup
gene_biotype: protein_coding
description:
  Putative potassium transport system protein Kup; Transport of potassium into the cell; Belongs to the HAK/KUP transporter (TC 2.A.72) family.


ensembl_gene_id: RGE_02540
symbol: metH
gene_biotype: protein_coding
description:
  Cobalamin-dependent methionine synthase MetH; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.


ensembl_gene_id: RGE_02550
symbol: glk-2
gene_biotype: protein_coding
description:
  Putative glucokinase/RipR family transcriptional regulator; Bifunctional protein; Belongs to the bacterial glucokinase family.


ensembl_gene_id: RGE_02630
symbol: malE
gene_biotype: protein_coding
description:
  Maltose ABC transporter, maltose-binding periplasmic protein MalE; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Binds maltose and higher maltodextrins. Belongs to the bacterial solute-binding protein 1 family.


ensembl_gene_id: RGE_02690
symbol: pcrA
gene_biotype: protein_coding
description:
  ATP-dependent DNA helicase PcrA; Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.


ensembl_gene_id: RGE_02770
symbol: RGE_02770
gene_biotype: protein_coding
description:
  TRAP dicarboxylate transporter- DctP subunit; Part of the tripartite ATP-independent periplasmic (TRAP) transport system.


ensembl_gene_id: RGE_02900
symbol: ybdK
gene_biotype: protein_coding
description:
  Carboxylate-amine ligase YbdK; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.


ensembl_gene_id: RGE_02940
symbol: rpe
gene_biotype: protein_coding
description:
  Ribulose-phosphate 3-epimerase Rpe; Protein synonym:pentose-5-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.


ensembl_gene_id: RGE_02980
symbol: RGE_02980
gene_biotype: protein_coding
description:
  Putative ABC transporter permease protein; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: RGE_03060
symbol: gph
gene_biotype: protein_coding
description:
  Phosphoglycolate phosphatase Gph; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.


ensembl_gene_id: RGE_03080
symbol: trpE
gene_biotype: protein_coding
description:
  Anthranilate synthase component I TrpE; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high con [...]


ensembl_gene_id: RGE_03100
symbol: trpD
gene_biotype: protein_coding
description:
  Anthranilate phosphoribosyltransferase TrpD; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).


ensembl_gene_id: RGE_03130
symbol: tuf
gene_biotype: protein_coding
description:
  Elongation factor Tu Tuf; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.


ensembl_gene_id: RGE_03150
symbol: nusG
gene_biotype: protein_coding
description:
  Transcriptional antiterminator NusG; Participates in transcription elongation, termination and antitermination.


ensembl_gene_id: RGE_03160
symbol: rplK
gene_biotype: protein_coding
description:
  50S ribosomal protein L11 RplK; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.


ensembl_gene_id: RGE_03170
symbol: rplA
gene_biotype: protein_coding
description:
  50S ribosomal protein L1 RplA; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.


ensembl_gene_id: RGE_03180
symbol: rplJ
gene_biotype: protein_coding
description:
  50S ribosomal protein L10 RplJ; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.


ensembl_gene_id: RGE_03190
symbol: rplL
gene_biotype: protein_coding
description:
  50S ribosomal protein L7/L12 RplL; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family.


ensembl_gene_id: RGE_03200
symbol: rpoB
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase subunit beta RpoB; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: RGE_03210
symbol: rpoC
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase subunit beta' RpoC; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: RGE_03240
symbol: rpsL
gene_biotype: protein_coding
description:
  30S ribosomal protein S12 RpsL; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.


ensembl_gene_id: RGE_03250
symbol: rpsG
gene_biotype: protein_coding
description:
  30S ribosomal protein S7 RpsG; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.


ensembl_gene_id: RGE_03260
symbol: fusA
gene_biotype: protein_coding
description:
  Elongation factor EF-G FusA; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.


ensembl_gene_id: RGE_03280
symbol: rpsJ
gene_biotype: protein_coding
description:
  30S ribosomal protein S10 RpsJ; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.


ensembl_gene_id: RGE_03290
symbol: rplC
gene_biotype: protein_coding
description:
  50S ribosomal protein L3 RplC; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.


ensembl_gene_id: RGE_03310
symbol: rplW
gene_biotype: protein_coding
description:
  50S ribosomal protein L23 RplW; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.


ensembl_gene_id: RGE_03320
symbol: rplB
gene_biotype: protein_coding
description:
  50S ribosomal protein L2 RplB; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.


ensembl_gene_id: RGE_03330
symbol: rpsS
gene_biotype: protein_coding
description:
  30S ribosomal protein S19 RpsS; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.


ensembl_gene_id: RGE_03340
symbol: rplV
gene_biotype: protein_coding
description:
  50S ribosomal protein L22 RplV; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.


ensembl_gene_id: RGE_03350
symbol: rpsC
gene_biotype: protein_coding
description:
  30S ribosomal protein S3 RpsC; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.


ensembl_gene_id: RGE_03360
symbol: rplP
gene_biotype: protein_coding
description:
  50S ribosomal protein L16 RplP; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.


ensembl_gene_id: RGE_03380
symbol: rpsQ
gene_biotype: protein_coding
description:
  30S ribosomal protein S17 RpsQ; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.


ensembl_gene_id: RGE_03390
symbol: RGE_03390
gene_biotype: protein_coding
description:
  peroxiredoxin-2E-1 like protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.


ensembl_gene_id: RGE_03400
symbol: rplN
gene_biotype: protein_coding
description:
  50S ribosomal protein L14 RplN; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.


ensembl_gene_id: RGE_03410
symbol: rplX
gene_biotype: protein_coding
description:
  50S ribosomal protein L24 RplX; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.


ensembl_gene_id: RGE_03420
symbol: rplE
gene_biotype: protein_coding
description:
  50S ribosomal protein L5 RplE; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.


ensembl_gene_id: RGE_03430
symbol: rpsN
gene_biotype: protein_coding
description:
  30S ribosomal protein S14 RpsN; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family.


ensembl_gene_id: RGE_03440
symbol: rpsH
gene_biotype: protein_coding
description:
  30S ribosomal protein S8 RpsH; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.


ensembl_gene_id: RGE_03450
symbol: rplF
gene_biotype: protein_coding
description:
  50S ribosomal protein L6 RplF; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.


ensembl_gene_id: RGE_03460
symbol: rplR
gene_biotype: protein_coding
description:
  50S ribosomal protein L18 RplR; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.


ensembl_gene_id: RGE_03470
symbol: rpsE
gene_biotype: protein_coding
description:
  30S ribosomal protein S5 RpsE; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.


ensembl_gene_id: RGE_03490
symbol: rplO
gene_biotype: protein_coding
description:
  50S ribosomal protein L15 RplO; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.


ensembl_gene_id: RGE_03500
symbol: secY
gene_biotype: protein_coding
description:
  Preprotein translocase SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.


ensembl_gene_id: RGE_03510
symbol: infA
gene_biotype: protein_coding
description:
  Translation initiation factor IF-1 InfA; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.


ensembl_gene_id: RGE_03530
symbol: rpsM
gene_biotype: protein_coding
description:
  30S ribosomal protein S13 RpsM; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family.


ensembl_gene_id: RGE_03540
symbol: rpsK
gene_biotype: protein_coding
description:
  30S ribosomal protein S11 RpsK; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.


ensembl_gene_id: RGE_03550
symbol: rpsD
gene_biotype: protein_coding
description:
  30S ribosomal protein S4 RpsD; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.


ensembl_gene_id: RGE_03560
symbol: rpoA
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase subunit alpha RpoA; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: RGE_03770
symbol: ybhO
gene_biotype: protein_coding
description:
  Putative cardiolipin synthetase YbhO; Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.


ensembl_gene_id: RGE_03830
symbol: nrdD
gene_biotype: protein_coding
description:
  Anaerobic ribonucleoside-triphosphate reductase NrdD; Protein synonym:class III ribonucleotide reductase.


ensembl_gene_id: RGE_03940
symbol: phnC
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family.


ensembl_gene_id: RGE_04130
symbol: wecB
gene_biotype: protein_coding
description:
  UDP-N-acetylglucosamine 2-epimerase WecB; Belongs to the UDP-N-acetylglucosamine 2-epimerase family.


ensembl_gene_id: RGE_04180
symbol: wecC
gene_biotype: protein_coding
description:
  UDP-N-acetyl-D-mannosamine dehydrogenase WecC; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.


ensembl_gene_id: RGE_04490
symbol: yajC
gene_biotype: protein_coding
description:
  Preprotein translocase YajC subunit; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.


ensembl_gene_id: RGE_04500
symbol: secD
gene_biotype: protein_coding
description:
  Preprotein translocase SecD subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.


ensembl_gene_id: RGE_04510
symbol: secF
gene_biotype: protein_coding
description:
  Preprotein translocase SecF subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.


ensembl_gene_id: RGE_04560
symbol: def
gene_biotype: protein_coding
description:
  Peptide deformylase Def; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.


ensembl_gene_id: RGE_04570
symbol: fmt
gene_biotype: protein_coding
description:
  methionyl-tRNA formyltransferase Fmt; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.


ensembl_gene_id: RGE_04650
symbol: cbbA
gene_biotype: protein_coding
description:
  Fructose-bisphosphate aldolase CbbA; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.


ensembl_gene_id: RGE_04660
symbol: purC
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazole-succinocarboxamide synthase PurC; Belongs to the SAICAR synthetase family.


ensembl_gene_id: RGE_04680
symbol: purE
gene_biotype: protein_coding
description:
  5-(carboxyamino)imidazole ribonucleotide mutase PurE; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).


ensembl_gene_id: RGE_04690
symbol: purK
gene_biotype: protein_coding
description:
  5-(carboxyamino)imidazole ribonucleotide synthase PurK; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).


ensembl_gene_id: RGE_04700
symbol: RGE_04700
gene_biotype: protein_coding
description:
  Sua5/YciO/YrdC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.


ensembl_gene_id: RGE_04750
symbol: dacB
gene_biotype: protein_coding
description:
  D-alanyl-D-alanine carboxypeptidase DacB; Protein synonym:D-alanyl-D-alanine endopeptidase; protein synonym:penicillin-binding protein 4.


ensembl_gene_id: RGE_04800
symbol: glmU
gene_biotype: protein_coding
description:
  Glucosamine-1-phosphate N-acetyltransferase / UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.


ensembl_gene_id: RGE_04830
symbol: ttcA
gene_biotype: protein_coding
description:
  Putative TtcA family protein; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.


ensembl_gene_id: RGE_04880
symbol: cca
gene_biotype: protein_coding
description:
  tRNA nucleotidyltransferase (CCA-adding enzyme); Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.


ensembl_gene_id: RGE_04980
symbol: metF
gene_biotype: protein_coding
description:
  Methylenetetrahydrofolate reductase MetF; Belongs to the methylenetetrahydrofolate reductase family.


ensembl_gene_id: RGE_04990
symbol: ahcY
gene_biotype: protein_coding
description:
  Adenosylhomocysteinase AhcY; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.


ensembl_gene_id: RGE_05030
symbol: purT
gene_biotype: protein_coding
description:
  Phosphoribosylglycinamide formyltransferase 2 PurT; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family.


ensembl_gene_id: RGE_05090
symbol: metK
gene_biotype: protein_coding
description:
  S-adenosylmethionine synthetase MetK; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.


ensembl_gene_id: RGE_05120
symbol: dapF
gene_biotype: protein_coding
description:
  Diaminopimelate epimerase DapF; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.


ensembl_gene_id: RGE_05140
symbol: xerC
gene_biotype: protein_coding
description:
  Tyrosine recombinase XerC; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.


ensembl_gene_id: RGE_05180
symbol: glmS
gene_biotype: protein_coding
description:
  Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.


ensembl_gene_id: RGE_05200
symbol: RGE_05200
gene_biotype: protein_coding
description:
  Alkylhydroperoxidase AhpD family core domain protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.


ensembl_gene_id: RGE_05290
symbol: pflA
gene_biotype: protein_coding
description:
  Pyruvate formate-lyase activating enzyme PflA; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family.


ensembl_gene_id: RGE_05400
symbol: fusA-2
gene_biotype: protein_coding
description:
  Elongation factor G FusA; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.


ensembl_gene_id: RGE_05460
symbol: kduI
gene_biotype: protein_coding
description:
  5-keto-4-deoxyuronate isomerase KduI; Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate. Belongs to the KduI family.


ensembl_gene_id: RGE_05480
symbol: kdgT
gene_biotype: protein_coding
description:
  2-keto-3-deoxygluconate transporter KdgT; The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system. Belongs to the KdgT transporter family.


ensembl_gene_id: RGE_05840
symbol: znuA
gene_biotype: protein_coding
description:
  Metal ABC transporter substrate binding protein ZnuA; Belongs to the bacterial solute-binding protein 9 family.


ensembl_gene_id: RGE_06230
symbol: modC
gene_biotype: protein_coding
description:
  Molybdenum ABC transporter,ATPase subunit ModC; Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Molybdate importer (TC 3.A.1.8) family.


ensembl_gene_id: RGE_06240
symbol: modB
gene_biotype: protein_coding
description:
  Molybdenum ABC transporter, permease protein ModB; Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: RGE_06680
symbol: map
gene_biotype: protein_coding
description:
  Methionine aminopeptidase Map; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.


ensembl_gene_id: RGE_06720
symbol: menD
gene_biotype: protein_coding
description:
  2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase MenD; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily.


ensembl_gene_id: RGE_06830
symbol: cas1
gene_biotype: protein_coding
description:
  CRISPR-associated protein, Cas1 family; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.


ensembl_gene_id: RGE_07090
symbol: sdaA
gene_biotype: protein_coding
description:
  L-serine dehydratase SdaA; Protein synonym:L-serine deaminase; Belongs to the iron-sulfur dependent L-serine dehydratase family.


ensembl_gene_id: RGE_07210
symbol: ytfE
gene_biotype: protein_coding
description:
  Regulator of cell morphogenesis and NO signaling; Di-iron-containing protein involved in the repair of iron- sulfur clusters; Belongs to the RIC family.


ensembl_gene_id: RGE_07440
symbol: pfp
gene_biotype: protein_coding
description:
  6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.


ensembl_gene_id: RGE_07550
symbol: srkA
gene_biotype: protein_coding
description:
  Aminoglycoside phosphotransferase; A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.


ensembl_gene_id: RGE_07580
symbol: rplM
gene_biotype: protein_coding
description:
  50S ribosomal protein L13 RplM; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.


ensembl_gene_id: RGE_07610
symbol: anmK
gene_biotype: protein_coding
description:
  anhydro-N-acetylmuramic acid kinase AnmK; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family.


ensembl_gene_id: RGE_07630
symbol: tyrS
gene_biotype: protein_coding
description:
  tyrosyl-tRNA synthetase TyrS; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.


ensembl_gene_id: RGE_07640
symbol: RGE_07640
gene_biotype: protein_coding
description:
  Putative cation transmembrane transporter; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.


ensembl_gene_id: RGE_07650
symbol: dtd
gene_biotype: protein_coding
description:
  D-tyrosyl-tRNA(Tyr) deacylase Dtd; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family.


ensembl_gene_id: RGE_07720
symbol: RGE_07720
gene_biotype: protein_coding
description:
  Putative branched-chain amino acid transport system permease; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: RGE_07940
symbol: gspE
gene_biotype: protein_coding
description:
  Putative general secretion pathway protein E GspE; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.


ensembl_gene_id: RGE_08060
symbol: ilvA
gene_biotype: protein_coding
description:
  Threonine dehydratase IlvA; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.


ensembl_gene_id: RGE_08080
symbol: coq7
gene_biotype: protein_coding
description:
  2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase Coq7; Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6- methoxy-1,4-benzoquinol during ubiquinone biosynthesis.


ensembl_gene_id: RGE_08130
symbol: lysA
gene_biotype: protein_coding
description:
  Diaminopimelate decarboxylase LysA; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.


ensembl_gene_id: RGE_08150
symbol: cyaY
gene_biotype: protein_coding
description:
  Hypothetical protein; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.


ensembl_gene_id: RGE_08240
symbol: aroK
gene_biotype: protein_coding
description:
  Shikimate kinase AroK; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.


ensembl_gene_id: RGE_08250
symbol: aroB
gene_biotype: protein_coding
description:
  3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).


ensembl_gene_id: RGE_08260
symbol: dgt
gene_biotype: protein_coding
description:
  Putative deoxyguanosinetriphosphate triphosphohydrolase Dgt; Belongs to the dGTPase family. Type 2 subfamily.


ensembl_gene_id: RGE_08370
symbol: zwf
gene_biotype: protein_coding
description:
  Glucose-6-phosphate 1-dehydrogenase Zwf; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.


ensembl_gene_id: RGE_08400
symbol: tal
gene_biotype: protein_coding
description:
  Transaldolase B Tal; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.


ensembl_gene_id: RGE_08410
symbol: pgi
gene_biotype: protein_coding
description:
  Glucose-6-phosphate isomerase Pgi; Protein synonym:phosphoglucose isomerase; protein synonym:phosphohexose isomerase; Belongs to the GPI family.


ensembl_gene_id: RGE_08460
symbol: RGE_08460
gene_biotype: protein_coding
description:
  Molybdopterin oxidoreductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: RGE_08550
symbol: clpP
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease, protease subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.


ensembl_gene_id: RGE_08570
symbol: murA
gene_biotype: protein_coding
description:
  UDP-N-acetylglucosamine 1-carboxyvinyltransferase MurA; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.


ensembl_gene_id: RGE_08580
symbol: hisG
gene_biotype: protein_coding
description:
  ATP phosphoribosyltransferase HisG; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily.


ensembl_gene_id: RGE_08590
symbol: hisD
gene_biotype: protein_coding
description:
  Histidinol dehydrogenase HisD; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.


ensembl_gene_id: RGE_08600
symbol: hisC
gene_biotype: protein_coding
description:
  Histidinol-phosphate aminotransferase HisC; Protein synonym:imidazole acetol-phosphate transaminase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.


ensembl_gene_id: RGE_08620
symbol: hisH
gene_biotype: protein_coding
description:
  Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.


ensembl_gene_id: RGE_08640
symbol: hisF
gene_biotype: protein_coding
description:
  Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.


ensembl_gene_id: RGE_08660
symbol: kdtB
gene_biotype: protein_coding
description:
  Pantetheine-phosphate adenylyltransferase KdtB; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.


ensembl_gene_id: RGE_08690
symbol: pth
gene_biotype: protein_coding
description:
  peptidyl-tRNA hydrolase Pth; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.


ensembl_gene_id: RGE_08700
symbol: rplY
gene_biotype: protein_coding
description:
  50S ribosomal protein L25 RplY; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.


ensembl_gene_id: RGE_08710
symbol: prs
gene_biotype: protein_coding
description:
  Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.


ensembl_gene_id: RGE_08720
symbol: ispE
gene_biotype: protein_coding
description:
  4-diphosphocytidyl-2-C-methyl-D-erythritol kinase IspE; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.


ensembl_gene_id: RGE_08730
symbol: RGE_08730
gene_biotype: protein_coding
description:
  Hypothetical protein; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.


ensembl_gene_id: RGE_08750
symbol: mutM
gene_biotype: protein_coding
description:
  formamidopyrimidine-DNA glycosylase/DNA-(apurinic or apyrimidinic site) lyase MutM; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.


ensembl_gene_id: RGE_08810
symbol: ppnK
gene_biotype: protein_coding
description:
  Putative inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.


ensembl_gene_id: RGE_08820
symbol: hrcA
gene_biotype: protein_coding
description:
  Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons.


ensembl_gene_id: RGE_09460
symbol: rsmH
gene_biotype: protein_coding
description:
  Ribosomal RNA small subunit methyltransferase H; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.


ensembl_gene_id: RGE_09470
symbol: ftsL
gene_biotype: protein_coding
description:
  Putative cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.


ensembl_gene_id: RGE_09480
symbol: ftsI
gene_biotype: protein_coding
description:
  Peptidoglycan synthetase FtsI; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily.


ensembl_gene_id: RGE_09490
symbol: murE
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-2, 6-diaminopimelate ligase MurE; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.


ensembl_gene_id: RGE_09500
symbol: murF
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase MurF; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.


ensembl_gene_id: RGE_09510
symbol: mraY
gene_biotype: protein_coding
description:
  phospho-N-acetylmuramoyl-pentapeptide- transferase MraY; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.


ensembl_gene_id: RGE_09520
symbol: murD
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoylalanine--D-glutamate ligase MurD; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.


ensembl_gene_id: RGE_09530
symbol: ftsW
gene_biotype: protein_coding
description:
  Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily.


ensembl_gene_id: RGE_09540
symbol: murG
gene_biotype: protein_coding
description:
  Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.


ensembl_gene_id: RGE_09560
symbol: ddl
gene_biotype: protein_coding
description:
  D-alanine--D-alanine ligase Ddl; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.


ensembl_gene_id: RGE_09570
symbol: ftsQ
gene_biotype: protein_coding
description:
  Polypeptide-transport-associated domain protein, FtsQ-type; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.


ensembl_gene_id: RGE_09580
symbol: ftsA
gene_biotype: protein_coding
description:
  Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.


ensembl_gene_id: RGE_09590
symbol: ftsZ
gene_biotype: protein_coding
description:
  Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.


ensembl_gene_id: RGE_09780
symbol: leuA
gene_biotype: protein_coding
description:
  2-isopropylmalate synthase LeuA; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.


ensembl_gene_id: RGE_09970
symbol: pta
gene_biotype: protein_coding
description:
  Phosphate acetyltransferase Pta; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.


ensembl_gene_id: RGE_10060
symbol: pldA
gene_biotype: protein_coding
description:
  Phospholipase A1 PldA; Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities. Belongs to the phospholipase A1 family.


ensembl_gene_id: RGE_10070
symbol: RGE_10070
gene_biotype: protein_coding
description:
  Oxidoreductase, 2OG-Fe(II) oxygenase family; Belongs to the iron/ascorbate-dependent oxidoreductase family.


ensembl_gene_id: RGE_10100
symbol: lpxC
gene_biotype: protein_coding
description:
  UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase LpxC; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family.


ensembl_gene_id: RGE_10140
symbol: ruvC
gene_biotype: protein_coding
description:
  Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.


ensembl_gene_id: RGE_10210
symbol: purH
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase; Bifunctional protein; protein synonym:bifunctional purine biosynthesis protein PurH.


ensembl_gene_id: RGE_10230
symbol: dusB
gene_biotype: protein_coding
description:
  tRNA-dihydrouridine synthase B DusB; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily.


ensembl_gene_id: RGE_10250
symbol: RGE_10250
gene_biotype: protein_coding
description:
  Carboxypeptidase; Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.


ensembl_gene_id: RGE_10290
symbol: argB
gene_biotype: protein_coding
description:
  Acetylglutamate kinase ArgB; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.


ensembl_gene_id: RGE_10360
symbol: hisI
gene_biotype: protein_coding
description:
  phosphoribosyl-AMP cyclohydrolase HisI; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.


ensembl_gene_id: RGE_10400
symbol: tatA
gene_biotype: protein_coding
description:
  Sec-independent protein translocase protein TatA; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.


ensembl_gene_id: RGE_10410
symbol: tatB
gene_biotype: protein_coding
description:
  Sec-independent protein translocase protein TatB; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.


ensembl_gene_id: RGE_10420
symbol: tatC
gene_biotype: protein_coding
description:
  Sec-independent protein translocase protein TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.


ensembl_gene_id: RGE_10450
symbol: pdxA
gene_biotype: protein_coding
description:
  4-hydroxythreonine-4-phosphate dehydrogenase PdxA; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).


ensembl_gene_id: RGE_10470
symbol: mscL
gene_biotype: protein_coding
description:
  Large conductance mechanosensitive channel protein MscL; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.


ensembl_gene_id: RGE_10480
symbol: petA
gene_biotype: protein_coding
description:
  Ubiquinol-cytochrome c reductase, iron-sulfur subunit PetA; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.


ensembl_gene_id: RGE_10490
symbol: petB
gene_biotype: protein_coding
description:
  Cytochrome b PetB; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.


ensembl_gene_id: RGE_10540
symbol: secA
gene_biotype: protein_coding
description:
  Preprotein translocase SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family.


ensembl_gene_id: RGE_10570
symbol: argJ
gene_biotype: protein_coding
description:
  Arginine biosynthesis bifunctional protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.


ensembl_gene_id: RGE_10590
symbol: ugpQ
gene_biotype: protein_coding
description:
  Cytoplasmic glycerophosphoryl diester phosphodiesterase UgpQ; Protein synonym:glycerophosphodiester phosphodiesterase.


ensembl_gene_id: RGE_10600
symbol: ugpC
gene_biotype: protein_coding
description:
  Sn-glycerol-3-phosphate ABC transporter ATP binding protein UgpC; Part of the ABC transporter complex UgpABCE involved in sn- glycerol-3-phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. sn-glycerol-3- phosphate importer (TC 3.A.1.1.3) family.


ensembl_gene_id: RGE_10610
symbol: ugpE
gene_biotype: protein_coding
description:
  Sn-glycerol-3-phosphate ABC transporter permease protein UgpE; Part of the binding-protein-dependent transport system for sn-glycerol-3-phosphate; probably responsible for the translocation of the substrate across the membrane.


ensembl_gene_id: RGE_10670
symbol: ubiE
gene_biotype: protein_coding
description:
  Ubiquinone/menaquinone biosynthesis methyltransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2).


ensembl_gene_id: RGE_10860
symbol: RGE_10860
gene_biotype: protein_coding
description:
  Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family.


ensembl_gene_id: RGE_10910
symbol: ubiB
gene_biotype: protein_coding
description:
  2-octaprenylphenol hydroxylase of ubiquinone biosynthetic pathway UbiB; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.


ensembl_gene_id: RGE_10940
symbol: aspS
gene_biotype: protein_coding
description:
  aspartyl-tRNA synthetase AspS; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.


ensembl_gene_id: RGE_10990
symbol: cls
gene_biotype: protein_coding
description:
  Putative cardiolipin synthetase; Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.


ensembl_gene_id: RGE_11110
symbol: tolB
gene_biotype: protein_coding
description:
  Protein TolB; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: RGE_11120
symbol: pal
gene_biotype: protein_coding
description:
  Putative peptidoglycan-associated lipoprotein Pal; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: RGE_11130
symbol: cpoB
gene_biotype: protein_coding
description:
  Tol-pal system protein YbgF; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family.


ensembl_gene_id: RGE_11180
symbol: hemL
gene_biotype: protein_coding
description:
  Glutamate-1-semialdehyde 2,1-aminomutase HemL; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: RGE_11320
symbol: RGE_11320
gene_biotype: protein_coding
description:
  Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: RGE_11350
symbol: frmA
gene_biotype: protein_coding
description:
  S-(hydroxymethyl)glutathione dehydrogenase FrmA; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.


ensembl_gene_id: RGE_11360
symbol: fghA
gene_biotype: protein_coding
description:
  S-formylglutathione hydrolase FghA; Serine hydrolase involved in the detoxification of formaldehyde.


ensembl_gene_id: RGE_11380
symbol: selA
gene_biotype: protein_coding
description:
  L-seryl-tRNA(Ser) selenium transferase SelA; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.


ensembl_gene_id: RGE_11390
symbol: fdhE
gene_biotype: protein_coding
description:
  Formate dehydrogenase accessory protein FdhE; Necessary for formate dehydrogenase activity. Belongs to the FdhE family.


ensembl_gene_id: RGE_11420
symbol: fdoG
gene_biotype: protein_coding
description:
  Formate dehydrogenase-O, major subunit, selenocysteine-containing FdoG; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: RGE_11440
symbol: fdhD
gene_biotype: protein_coding
description:
  Formate dehydrogenase family accessory protein FdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.


ensembl_gene_id: RGE_11470
symbol: RGE_11470
gene_biotype: protein_coding
description:
  Zinc-binding alcohol dehydrogenase family protein, putative; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.


ensembl_gene_id: RGE_11760
symbol: argG
gene_biotype: protein_coding
description:
  Argininosuccinate synthase ArgG; Protein synonym:citrulline--aspartate ligase; Belongs to the argininosuccinate synthase family. Type 2 subfamily.


ensembl_gene_id: RGE_11820
symbol: serC
gene_biotype: protein_coding
description:
  Phosphoserine aminotransferase SerC; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.


ensembl_gene_id: RGE_12240
symbol: mdh
gene_biotype: protein_coding
description:
  Malate dehydrogenase Mdh; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.


ensembl_gene_id: RGE_12280
symbol: sdhA
gene_biotype: protein_coding
description:
  Succinate dehydrogenase flavoprotein subunit SdhA; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.


ensembl_gene_id: RGE_12290
symbol: sdhB
gene_biotype: protein_coding
description:
  Succinate dehydrogenase iron-sulfur subunit SdhB; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.


ensembl_gene_id: RGE_12330
symbol: sucD
gene_biotype: protein_coding
description:
  succinyl-CoA ligase[ADP-forming] subunit alpha SucD; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.


ensembl_gene_id: RGE_12340
symbol: sucC
gene_biotype: protein_coding
description:
  succinyl-CoA ligase[ADP-forming] subunit bata SucC; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.


ensembl_gene_id: RGE_12420
symbol: bioB
gene_biotype: protein_coding
description:
  Biotin synthase BioB; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.


ensembl_gene_id: RGE_12460
symbol: leuC
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydratase large LeuC; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.


ensembl_gene_id: RGE_12480
symbol: leuD
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydratase small subunit LeuD; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.


ensembl_gene_id: RGE_12490
symbol: leuB
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydrogenase LeuB; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.


ensembl_gene_id: RGE_12500
symbol: asd
gene_biotype: protein_coding
description:
  Aspartate-semialdehyde dehydrogenase Asd; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.


ensembl_gene_id: RGE_12520
symbol: truA
gene_biotype: protein_coding
description:
  tRNA pseudouridine synthase A TruA; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.


ensembl_gene_id: RGE_12540
symbol: trpB
gene_biotype: protein_coding
description:
  Tryptophan synthase beta chain TrpB; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.


ensembl_gene_id: RGE_12550
symbol: trpA
gene_biotype: protein_coding
description:
  Tryptophan synthase alpha chain TrpA; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.


ensembl_gene_id: RGE_12560
symbol: accD
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase carboxyl transferase subunit beta AccD; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.


ensembl_gene_id: RGE_12570
symbol: folC
gene_biotype: protein_coding
description:
  Bifunctional folylpolyglutamate synthase and dihydrofolate synthase; Belongs to the folylpolyglutamate synthase family.


ensembl_gene_id: RGE_12600
symbol: purF
gene_biotype: protein_coding
description:
  Amidophosphoribosyltransferase PurF; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.


ensembl_gene_id: RGE_12610
symbol: metZ
gene_biotype: protein_coding
description:
  O-succinylhomoserine sulfhydrylase MetZ; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.


ensembl_gene_id: RGE_12620
symbol: gltX
gene_biotype: protein_coding
description:
  glutamyl-tRNA synthetase GltX; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.


ensembl_gene_id: RGE_13090
symbol: RGE_13090
gene_biotype: protein_coding
description:
  Putative undecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP); Belongs to the UppP family.


ensembl_gene_id: RGE_13120
symbol: dnaE
gene_biotype: protein_coding
description:
  Error-prone DNA polymerase DnaE; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.


ensembl_gene_id: RGE_13220
symbol: kynU
gene_biotype: protein_coding
description:
  Kynureninase KynU; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively.


ensembl_gene_id: RGE_13230
symbol: kynB
gene_biotype: protein_coding
description:
  Putative cyclase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation.


ensembl_gene_id: RGE_13320
symbol: argF
gene_biotype: protein_coding
description:
  Ornithine carbamoyltransferase ArgF; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.


ensembl_gene_id: RGE_13330
symbol: argD
gene_biotype: protein_coding
description:
  Acetylornithine aminotransferase ArgD; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.


ensembl_gene_id: RGE_13360
symbol: mviN
gene_biotype: protein_coding
description:
  Integral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.


ensembl_gene_id: RGE_13400
symbol: pcnB
gene_biotype: protein_coding
description:
  poly(A) polymerase PcnB; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control. Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.


ensembl_gene_id: RGE_13480
symbol: rimM
gene_biotype: protein_coding
description:
  16S rRNA processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family.


ensembl_gene_id: RGE_13490
symbol: trmD
gene_biotype: protein_coding
description:
  tRNA (guanine-N1-)-methyltransferase TrmD; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.


ensembl_gene_id: RGE_13500
symbol: rplS
gene_biotype: protein_coding
description:
  50S ribosomal protein L19 RplS; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.


ensembl_gene_id: RGE_13520
symbol: cbiB
gene_biotype: protein_coding
description:
  Cobalamin biosynthesis protein CbiB; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.


ensembl_gene_id: RGE_13530
symbol: rsgA
gene_biotype: protein_coding
description:
  Putative ribosome biogenesis GTPase RsgA; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.


ensembl_gene_id: RGE_13550
symbol: orn
gene_biotype: protein_coding
description:
  Oligoribonuclease Orn; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family.


ensembl_gene_id: RGE_13610
symbol: gluQ
gene_biotype: protein_coding
description:
  glutamyl-Q tRNA(Asp) synthetase GluQ; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.


ensembl_gene_id: RGE_13720
symbol: gmhA-2
gene_biotype: protein_coding
description:
  Phosphoheptose isomerase GmhA; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.


ensembl_gene_id: RGE_13830
symbol: msbA
gene_biotype: protein_coding
description:
  Lipid A ABC transporter permease/ATP-binding protein MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.


ensembl_gene_id: RGE_13840
symbol: lapB
gene_biotype: protein_coding
description:
  TPR repeat protein; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane; Belongs to the LapB family.


ensembl_gene_id: RGE_13860
symbol: ihfB
gene_biotype: protein_coding
description:
  Integration host factor subunit beta IhfB; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.


ensembl_gene_id: RGE_13870
symbol: rpsA
gene_biotype: protein_coding
description:
  30S ribosomal protein S1 RpsA; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.


ensembl_gene_id: RGE_13880
symbol: aroA
gene_biotype: protein_coding
description:
  3-phosphoshikimate 1-carboxyvinyltransferase AroA; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate; Belongs to the cytidylate kinase family. Type 1 subfamily.


ensembl_gene_id: RGE_13920
symbol: gyrA
gene_biotype: protein_coding
description:
  DNA gyrase subunit A GyrA; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.


ensembl_gene_id: RGE_13940
symbol: ubiG
gene_biotype: protein_coding
description:
  3-demethylubiquinone-9 3-methyltransferase UbiG; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family.


ensembl_gene_id: RGE_14000
symbol: lspA
gene_biotype: protein_coding
description:
  Lipoprotein signal peptidase LspA; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.


ensembl_gene_id: RGE_14020
symbol: ileS
gene_biotype: protein_coding
description:
  isoleucyl-tRNA synthetase IleS; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.


ensembl_gene_id: RGE_14040
symbol: RGE_14040
gene_biotype: protein_coding
description:
  Putative riboflavin kinase/FMN adenylyltransferase; Bifunctional protein; Belongs to the ribF family.


ensembl_gene_id: RGE_14050
symbol: rsuA
gene_biotype: protein_coding
description:
  Ribosomal small subunit pseudouridine synthase A RsuA; Belongs to the pseudouridine synthase RsuA family.


ensembl_gene_id: RGE_14210
symbol: pfkA
gene_biotype: protein_coding
description:
  6-phosphofructokinase PfkA; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.


ensembl_gene_id: RGE_14310
symbol: aroQ
gene_biotype: protein_coding
description:
  3-dehydroquinate dehydratase AroQ; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.


ensembl_gene_id: RGE_14320
symbol: gshA-2
gene_biotype: protein_coding
description:
  Glutamate--cysteine ligase GshA; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.


ensembl_gene_id: RGE_14330
symbol: crcB
gene_biotype: protein_coding
description:
  Protein CrcB homolog; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.


ensembl_gene_id: RGE_14400
symbol: ntrC
gene_biotype: protein_coding
description:
  Nitrogen metabolism transcriptional regulator NtrC; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.


ensembl_gene_id: RGE_14470
symbol: folA
gene_biotype: protein_coding
description:
  Dihydrofolate reductase FolA; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.


ensembl_gene_id: RGE_14480
symbol: thyA
gene_biotype: protein_coding
description:
  Thymidylate synthase ThyA; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.


ensembl_gene_id: RGE_14570
symbol: miaA
gene_biotype: protein_coding
description:
  tRNA dimethylallyltransferase MiaA; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.


ensembl_gene_id: RGE_14590
symbol: rluF
gene_biotype: protein_coding
description:
  Ribosomal large subunit pseudouridine synthase F RluF; Belongs to the pseudouridine synthase RsuA family.


ensembl_gene_id: RGE_14740
symbol: mutL
gene_biotype: protein_coding
description:
  DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.


ensembl_gene_id: RGE_14810
symbol: queG
gene_biotype: protein_coding
description:
  Putative 4Fe-4S cluster-binding ferredoxin protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family.


ensembl_gene_id: RGE_14850
symbol: xerD
gene_biotype: protein_coding
description:
  Tyrosine recombinase XerD; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.


ensembl_gene_id: RGE_14870
symbol: argD-2
gene_biotype: protein_coding
description:
  Acetylornithine aminotransferase ArgD; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: RGE_14910
symbol: RGE_14910
gene_biotype: protein_coding
description:
  Putative ABC transporter substrate binding protein; Belongs to the bacterial solute-binding protein 3 family.


ensembl_gene_id: RGE_14920
symbol: RGE_14920
gene_biotype: protein_coding
description:
  Hypothetical protein; Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC); Belongs to the peptidase M81 family.


ensembl_gene_id: RGE_14950
symbol: hslO
gene_biotype: protein_coding
description:
  33 kDa chaperonin HslO; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress; Belongs to the HSP33 family.


ensembl_gene_id: RGE_14980
symbol: ftsB
gene_biotype: protein_coding
description:
  Cell division protein FtsB; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.


ensembl_gene_id: RGE_14990
symbol: eno
gene_biotype: protein_coding
description:
  Enolase Eno; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.


ensembl_gene_id: RGE_15010
symbol: kdsA
gene_biotype: protein_coding
description:
  2-dehydro-3-deoxyphosphooctonate aldolase KdsA; Protein synonym:3-deoxy-D-manno-octulosonic acid 8-phosphate synthetase; protein synonym:KDO 8-P synthase; protein synonym:KDO-8-phosphate synthetase; protein synonym:KDOPS; protein synonym:phospho-2-dehydro-3-deoxyoctonate aldolase; Belongs to the KdsA family.


ensembl_gene_id: RGE_15020
symbol: pyrG
gene_biotype: protein_coding
description:
  CTP synthase PyrG; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.


ensembl_gene_id: RGE_15040
symbol: cobU
gene_biotype: protein_coding
description:
  Bifunctional adenosylcobalamin biosynthesis protein CobU; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.


ensembl_gene_id: RGE_15060
symbol: RGE_15060
gene_biotype: protein_coding
description:
  ABC transporter permease protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: RGE_15080
symbol: cobQ
gene_biotype: protein_coding
description:
  Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.


ensembl_gene_id: RGE_15090
symbol: cobT-2
gene_biotype: protein_coding
description:
  Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase CobT; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).


ensembl_gene_id: RGE_15100
symbol: cobS
gene_biotype: protein_coding
description:
  Cobalamin-5'-phosphate synthase CobS; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.


ensembl_gene_id: RGE_15160
symbol: mutS
gene_biotype: protein_coding
description:
  DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.


ensembl_gene_id: RGE_15180
symbol: trmJ
gene_biotype: protein_coding
description:
  tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.


ensembl_gene_id: RGE_15230
symbol: RGE_15230
gene_biotype: protein_coding
description:
  TRAP dicarboxylate transporter-DctP subunit; Part of the tripartite ATP-independent periplasmic (TRAP) transport system.


ensembl_gene_id: RGE_15350
symbol: nth
gene_biotype: protein_coding
description:
  Endonuclease III Nth; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.


ensembl_gene_id: RGE_15360
symbol: rnfB
gene_biotype: protein_coding
description:
  Electron transport complex, RnfABCDGE type, B subunit RnfB; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.


ensembl_gene_id: RGE_15390
symbol: uvrB
gene_biotype: protein_coding
description:
  UvrABC system protein B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and [...]


ensembl_gene_id: RGE_15400
symbol: ptpA
gene_biotype: protein_coding
description:
  Putative protein-tyrosine phosphatase; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.


ensembl_gene_id: RGE_15420
symbol: iscS
gene_biotype: protein_coding
description:
  Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.


ensembl_gene_id: RGE_15430
symbol: iscU
gene_biotype: protein_coding
description:
  Fe-S cluster assembly scaffold protein IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.


ensembl_gene_id: RGE_15460
symbol: hscB
gene_biotype: protein_coding
description:
  Co-chaperone protein HscB homolog; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family.


ensembl_gene_id: RGE_15470
symbol: hscA
gene_biotype: protein_coding
description:
  Chaperone protein HscA homolog; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.


ensembl_gene_id: RGE_15490
symbol: gcp
gene_biotype: protein_coding
description:
  Putative O-sialoglycoprotein endopeptidase Gcp; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.


ensembl_gene_id: RGE_15520
symbol: rpsO
gene_biotype: protein_coding
description:
  30S ribosomal protein S15 RpsO; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.


ensembl_gene_id: RGE_15530
symbol: pnp
gene_biotype: protein_coding
description:
  Polyribonucleotide nucleotidyltransferase Pnp; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.


ensembl_gene_id: RGE_15550
symbol: tpiA
gene_biotype: protein_coding
description:
  Triosephosphate isomerase TpiA; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.


ensembl_gene_id: RGE_15560
symbol: secG
gene_biotype: protein_coding
description:
  Preprotein translocase SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.


ensembl_gene_id: RGE_15570
symbol: nuoA
gene_biotype: protein_coding
description:
  NADH-quinone oxidoreductase, A subunit NuoA; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family.


ensembl_gene_id: RGE_15580
symbol: nuoB
gene_biotype: protein_coding
description:
  NADH-quinone oxidoreductase, B subunit NuoB; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: RGE_15590
symbol: nuoC
gene_biotype: protein_coding
description:
  NADH-quinone oxidoreductase, C subunit NuoC; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 30 kDa subunit family.


ensembl_gene_id: RGE_15600
symbol: nuoD
gene_biotype: protein_coding
description:
  NADH-quinone oxidoreductase, D subunit NuoD; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family.


ensembl_gene_id: RGE_15620
symbol: nuoF
gene_biotype: protein_coding
description:
  NADH-quinone oxidoreductase, F subunit NuoF; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family.


ensembl_gene_id: RGE_15630
symbol: nuoG
gene_biotype: protein_coding
description:
  NADH-quinone oxidoreductase, G subunit NuoG; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family.


ensembl_gene_id: RGE_15640
symbol: nuoH
gene_biotype: protein_coding
description:
  NADH-quinone oxidoreductase, H subunit NuoH; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.


ensembl_gene_id: RGE_15650
symbol: nuoI
gene_biotype: protein_coding
description:
  NADH-quinone oxidoreductase, I subunit NuoI; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: RGE_15660
symbol: nuoJ
gene_biotype: protein_coding
description:
  NADH-quinone oxidoreductase, J subunit NuoJ; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: RGE_15670
symbol: nuoK
gene_biotype: protein_coding
description:
  NADH-quinone oxidoreductase, K subunit NuoK; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family.


ensembl_gene_id: RGE_15700
symbol: nuoN
gene_biotype: protein_coding
description:
  NADH-quinone oxidoreductase, N subunit NuoN; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family.


ensembl_gene_id: RGE_15840
symbol: aroC
gene_biotype: protein_coding
description:
  Chorismate synthase AroC; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.


ensembl_gene_id: RGE_15880
symbol: RGE_15880
gene_biotype: protein_coding
description:
  Transporter, AcrB/D/F family protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: RGE_15940
symbol: gcvP
gene_biotype: protein_coding
description:
  Glycine dehydrogenase GcvP; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.


ensembl_gene_id: RGE_15950
symbol: gcvH
gene_biotype: protein_coding
description:
  Glycine cleavage system H protein GcvH; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.


ensembl_gene_id: RGE_16000
symbol: RGE_16000
gene_biotype: protein_coding
description:
  Putative electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone.


ensembl_gene_id: RGE_16150
symbol: pyrD
gene_biotype: protein_coding
description:
  Dihydroorotate dehydrogenase PyrD; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.


ensembl_gene_id: RGE_16160
symbol: rpiA
gene_biotype: protein_coding
description:
  Ribose-5-phosphate isomerase A RpiA; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.


ensembl_gene_id: RGE_16180
symbol: mnmC
gene_biotype: protein_coding
description:
  Putative oxidoreductase; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family.


ensembl_gene_id: RGE_16200
symbol: efp
gene_biotype: protein_coding
description:
  Elongation factor P Efp; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.


ensembl_gene_id: RGE_16220
symbol: uvrC
gene_biotype: protein_coding
description:
  UvrABC system protein C UvrC; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.


ensembl_gene_id: RGE_16240
symbol: pgsA
gene_biotype: protein_coding
description:
  CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase PgsA; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: RGE_16250
symbol: hupB
gene_biotype: protein_coding
description:
  DNA-binding protein HU-beta HupB; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.


ensembl_gene_id: RGE_16580
symbol: bchI
gene_biotype: protein_coding
description:
  Protoporphyrin IX magnesium-chelatase BchI; Involved in bacteriochlorophyll biosynthesis; introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX.


ensembl_gene_id: RGE_16670
symbol: xseB
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease 7 small subunit XseB; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.


ensembl_gene_id: RGE_16690
symbol: dxs
gene_biotype: protein_coding
description:
  1-deoxy-D-xylulose-5-phosphate synthase Dxs; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.


ensembl_gene_id: RGE_16710
symbol: fliR
gene_biotype: protein_coding
description:
  Flagellar biosynthetic protein FliR; Role in flagellar biosynthesis. Belongs to the FliR/MopE/SpaR family.


ensembl_gene_id: RGE_16720
symbol: fliQ
gene_biotype: protein_coding
description:
  Flagellar biosynthetic protein FliQ; Role in flagellar biosynthesis. Belongs to the FliQ/MopD/SpaQ family.


ensembl_gene_id: RGE_16730
symbol: fliP
gene_biotype: protein_coding
description:
  Flagellar biosynthetic protein FliP; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family.


ensembl_gene_id: RGE_16770
symbol: fliL
gene_biotype: protein_coding
description:
  Flagellar protein FliL; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.


ensembl_gene_id: RGE_16830
symbol: fliF
gene_biotype: protein_coding
description:
  Flagellar M-ring protein FliF; The M ring may be actively involved in energy transduction. Belongs to the FliF family.


ensembl_gene_id: RGE_16880
symbol: pilZ
gene_biotype: protein_coding
description:
  Putative type IV pilus assembly PilZ; Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility.


ensembl_gene_id: RGE_16910
symbol: fliD
gene_biotype: protein_coding
description:
  Flagellar hook-associated protein 2 FliD; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.


ensembl_gene_id: RGE_16920
symbol: fliC
gene_biotype: protein_coding
description:
  Flagellin FliC; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.


ensembl_gene_id: RGE_16940
symbol: fliC-3
gene_biotype: protein_coding
description:
  Flagellin FriC; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.


ensembl_gene_id: RGE_17030
symbol: flhD
gene_biotype: protein_coding
description:
  Flagellar transcriptional activator FlhD; Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhD family.


ensembl_gene_id: RGE_17040
symbol: flhC
gene_biotype: protein_coding
description:
  Flagellar transcriptional activator FlhC; Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhC family.


ensembl_gene_id: RGE_17100
symbol: flhB
gene_biotype: protein_coding
description:
  Flagellar biosynthetic protein FlhB; Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the type III secretion exporter family.


ensembl_gene_id: RGE_17110
symbol: flhA
gene_biotype: protein_coding
description:
  Flagellar biosynthesis protein FlhA; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.


ensembl_gene_id: RGE_17120
symbol: flhF
gene_biotype: protein_coding
description:
  GTP-binding signal recognition particle SRP54 G-domain FlhF; Protein synonym:flagella-associated GTP-binding protein FlhF.


ensembl_gene_id: RGE_17140
symbol: filA
gene_biotype: protein_coding
description:
  RNA polymerase sigma factor for flagellar operon FliA; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily.


ensembl_gene_id: RGE_17190
symbol: flgA
gene_biotype: protein_coding
description:
  Flagella basal body P-ring formation protein FlgA; Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P- ring assembly; Belongs to the FlgA family.


ensembl_gene_id: RGE_17200
symbol: flgB
gene_biotype: protein_coding
description:
  Flagellar basal-body rod protein FlgB; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.


ensembl_gene_id: RGE_17220
symbol: flgD
gene_biotype: protein_coding
description:
  Flagellar basal-body rod modification protein FlgD; Required for flagellar hook formation. May act as a scaffolding protein.


ensembl_gene_id: RGE_17260
symbol: RGE_17260
gene_biotype: protein_coding
description:
  3-oxoacyl-[acyl-carrier-protein] synthase II; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: RGE_17320
symbol: flgH
gene_biotype: protein_coding
description:
  Flagellar L-ring protein FlgH; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.


ensembl_gene_id: RGE_17330
symbol: flgI
gene_biotype: protein_coding
description:
  Flagellar P-ring protein FlgI; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.


ensembl_gene_id: RGE_17670
symbol: rbsD
gene_biotype: protein_coding
description:
  High affinity ribose transport protein RbsD; Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.


ensembl_gene_id: RGE_17680
symbol: rbsK
gene_biotype: protein_coding
description:
  Ribokinase RbsK; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.


ensembl_gene_id: RGE_17700
symbol: rbsC
gene_biotype: protein_coding
description:
  Ribose ABC transporter permease protein RbsC; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: RGE_18220
symbol: apaH
gene_biotype: protein_coding
description:
  Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) ApaH; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family.


ensembl_gene_id: RGE_18250
symbol: dusC
gene_biotype: protein_coding
description:
  tRNA-dihydrouridine synthase C DusC; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs. Belongs to the Dus family. DusC subfamily.


ensembl_gene_id: RGE_18330
symbol: aceE
gene_biotype: protein_coding
description:
  Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


ensembl_gene_id: RGE_18490
symbol: prfB
gene_biotype: protein_coding
description:
  Peptide chain release factor RF-2 PrfB; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.


ensembl_gene_id: RGE_18530
symbol: acsA
gene_biotype: protein_coding
description:
  Acetyl-coenzyme A synthetase AcsA; Protein synonym:acetate--CoA ligase; protein synonym:acyl-activating enzyme.


ensembl_gene_id: RGE_18580
symbol: plsY
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.


ensembl_gene_id: RGE_18620
symbol: RGE_18620
gene_biotype: protein_coding
description:
  Fumarate hydratase class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.


ensembl_gene_id: RGE_18640
symbol: acsA-2
gene_biotype: protein_coding
description:
  Acetyl-coenzyme A synthetase AcsA; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.


ensembl_gene_id: RGE_18660
symbol: lgt
gene_biotype: protein_coding
description:
  Prolipoprotein diacylglyceryl transferase Lgt; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.


ensembl_gene_id: RGE_18670
symbol: dnaQ
gene_biotype: protein_coding
description:
  DNA polymerase III epsilon subunit DnaQ; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.


ensembl_gene_id: RGE_18740
symbol: cobI
gene_biotype: protein_coding
description:
  Precorrin-2 C20-methyltransferase CobI; Methylates precorrin-2 at the C-20 position to produce precorrin-3A.


ensembl_gene_id: RGE_18800
symbol: cobB
gene_biotype: protein_coding
description:
  Cobyrinic acid A,C-diamide synthase CobB; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.


ensembl_gene_id: RGE_19040
symbol: glgB
gene_biotype: protein_coding
description:
  Putative 1,4-alpha-glucan-branching enzyme GlgB; Protein synonym:putative 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase; protein synonym:putative glycogen-branching enzyme BE.


ensembl_gene_id: RGE_19230
symbol: nosX
gene_biotype: protein_coding
description:
  Nitrous-oxide reductase protein NosX, putative; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. Belongs to the ApbE family.


ensembl_gene_id: RGE_19400
symbol: panB
gene_biotype: protein_coding
description:
  3-methyl-2-oxobutanoate hydroxymethyltransferase PanB; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.


ensembl_gene_id: RGE_19410
symbol: panC
gene_biotype: protein_coding
description:
  Pantothenate synthetase PanC; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.


ensembl_gene_id: RGE_19430
symbol: azoR
gene_biotype: protein_coding
description:
  FMN-dependent NADH-azoreductase AzoR; Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity; Belongs to the azoreductase type 1 family.


ensembl_gene_id: RGE_19460
symbol: lafA
gene_biotype: protein_coding
description:
  Lateral flagellin LafA; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.


ensembl_gene_id: RGE_19570
symbol: lfiQ
gene_biotype: protein_coding
description:
  Lateral flagellar export/assembly protein LfiQ; Role in flagellar biosynthesis. Belongs to the FliQ/MopD/SpaQ family.


ensembl_gene_id: RGE_19580
symbol: lfiP
gene_biotype: protein_coding
description:
  Lateral flagellar export/assembly protein LfiP; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family.


ensembl_gene_id: RGE_19620
symbol: lfiF
gene_biotype: protein_coding
description:
  Lateral flagellar M-ring protein LfiF; The M ring may be actively involved in energy transduction. Belongs to the FliF family.


ensembl_gene_id: RGE_19670
symbol: lafB
gene_biotype: protein_coding
description:
  Lateral flagellar hook-associated protein 2; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.


ensembl_gene_id: RGE_19710
symbol: lafF
gene_biotype: protein_coding
description:
  Flagellar basal body-associated protein LafF; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.


ensembl_gene_id: RGE_19780
symbol: lfgA
gene_biotype: protein_coding
description:
  Lateral flagellar P-ring addition protein LfgA; Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P- ring assembly; Belongs to the FlgA family.


ensembl_gene_id: RGE_19790
symbol: lfgB
gene_biotype: protein_coding
description:
  Lateral flagellar rod protein LfgB; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.


ensembl_gene_id: RGE_19800
symbol: lfgC
gene_biotype: protein_coding
description:
  Lateral flagellar basal-body rod protein LfgC; Belongs to the flagella basal body rod proteins family.


ensembl_gene_id: RGE_19810
symbol: lfgD
gene_biotype: protein_coding
description:
  Putative basal-body rod modification protein LfgD; Required for flagellar hook formation. May act as a scaffolding protein.


ensembl_gene_id: RGE_19850
symbol: lfgH
gene_biotype: protein_coding
description:
  Lateral flagellar L-ring protein LfgH; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.


ensembl_gene_id: RGE_19860
symbol: lfgI
gene_biotype: protein_coding
description:
  Lateral flagellar P-ring protein LfgI; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.


ensembl_gene_id: RGE_19940
symbol: RGE_19940
gene_biotype: protein_coding
description:
  Cysteine desulfurase, SufS subfamily; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.


ensembl_gene_id: RGE_20320
symbol: dmsA
gene_biotype: protein_coding
description:
  Dimethylsulfoxide (DMSO) reductase, A subunit DmsA; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: RGE_20700
symbol: kdpC
gene_biotype: protein_coding
description:
  Potassium-transporting ATPase C chain KdpC; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.


ensembl_gene_id: RGE_20710
symbol: kdpB
gene_biotype: protein_coding
description:
  Potassium-transporting ATPase B chain KdpB; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.


ensembl_gene_id: RGE_20720
symbol: kdpA
gene_biotype: protein_coding
description:
  Potassium-transporting ATPase A chain KdpA; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane.


ensembl_gene_id: RGE_20740
symbol: apbA-2
gene_biotype: protein_coding
description:
  2-dehydropantoate 2-reductase ApbA; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.


ensembl_gene_id: RGE_20780
symbol: arsC
gene_biotype: protein_coding
description:
  Putative arsenate reductase; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.


ensembl_gene_id: RGE_20790
symbol: RGE_20790
gene_biotype: protein_coding
description:
  Putative tyrosine phosphatase; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.


ensembl_gene_id: RGE_20890
symbol: RGE_20890
gene_biotype: protein_coding
description:
  Putative ABC transporter ATP-binding protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.


ensembl_gene_id: RGE_20920
symbol: mtnD
gene_biotype: protein_coding
description:
  Putative acireductone dioxygenase (Ni2+ or Fe2+-requiring) MtnD; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.


ensembl_gene_id: RGE_20960
symbol: rnfB-2
gene_biotype: protein_coding
description:
  Electron transport complex, RnfABCDGE type, B subunit /ferredoxin RnfB; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.


ensembl_gene_id: RGE_20980
symbol: rnfC
gene_biotype: protein_coding
description:
  Electron transport complex, RnfABCDGE type, C subunit RnfC; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.


ensembl_gene_id: RGE_20990
symbol: rnfD
gene_biotype: protein_coding
description:
  Electron transport complex, RnfABCDGE type, D subunit RnfD; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the NqrB/RnfD family.


ensembl_gene_id: RGE_21010
symbol: rnfE
gene_biotype: protein_coding
description:
  Electron transport complex, RnfABCDGE type, E subunit RnfE; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.


ensembl_gene_id: RGE_21020
symbol: rnfA
gene_biotype: protein_coding
description:
  Electron transport complex, RnfABCDGE type, A subunit RnfA; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.


ensembl_gene_id: RGE_21050
symbol: RGE_21050
gene_biotype: protein_coding
description:
  ApbE family lipoprotein; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. Belongs to the ApbE family.


ensembl_gene_id: RGE_21140
symbol: fdxA
gene_biotype: protein_coding
description:
  4Fe-4S ferredoxin, iron-sulfur binding FdxA; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.


ensembl_gene_id: RGE_21240
symbol: pyc
gene_biotype: protein_coding
description:
  Pyruvate carboxylase Pyc; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.


ensembl_gene_id: RGE_21250
symbol: frdD
gene_biotype: protein_coding
description:
  Fumarate reductase subunit D FrdD; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane; Belongs to the FrdD family.


ensembl_gene_id: RGE_21410
symbol: petA2
gene_biotype: protein_coding
description:
  Ubiquinol-cytochrome c reductase, iron-sulfur subunit PetA2; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.


ensembl_gene_id: RGE_21450
symbol: ate
gene_biotype: protein_coding
description:
  Putative arginyl-tRNA--protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate. Belongs to the R-transferase family. Bpt subfamily.


ensembl_gene_id: RGE_21460
symbol: aat
gene_biotype: protein_coding
description:
  leucyl/phenylalanyl-tRNA--protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.


ensembl_gene_id: RGE_21560
symbol: lolD
gene_biotype: protein_coding
description:
  Lipoprotein ABC transporter ATP binding protein LolD; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.


ensembl_gene_id: RGE_21870
symbol: pssA
gene_biotype: protein_coding
description:
  Phosphatidylserine synthase PssA; Protein synonym:CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: RGE_22040
symbol: ccmA
gene_biotype: protein_coding
description:
  Cytochrome c-type biogenesis protein CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.


ensembl_gene_id: RGE_22070
symbol: ccmB
gene_biotype: protein_coding
description:
  Cytochrome c-type biogenesis protein CcmB; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family.


ensembl_gene_id: RGE_22080
symbol: ccmC
gene_biotype: protein_coding
description:
  Cytochrome c-type biogenesis protein CcmC; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family.


ensembl_gene_id: RGE_22090
symbol: ccmD
gene_biotype: protein_coding
description:
  Cytochrome c-type biogenesis protein CcmD; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmD/CycX/HelD family.


ensembl_gene_id: RGE_22100
symbol: ccmE
gene_biotype: protein_coding
description:
  Cytochrome c-type biogenesis protein CcmE; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family.


ensembl_gene_id: RGE_22360
symbol: malQ
gene_biotype: protein_coding
description:
  4-alpha-glucanotransferase MalQ; Protein synonym:amylomaltase; protein synonym:disproportionating enzyme.


ensembl_gene_id: RGE_22420
symbol: dctA
gene_biotype: protein_coding
description:
  C4-dicarboxylate transport protein DctA; Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane. Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: RGE_22830
symbol: cowN
gene_biotype: protein_coding
description:
  Hypothetical protein; Is required to sustain N(2)-dependent growth in the presence of low levels of carbon monoxide (CO). Probably acts by protecting the N(2) fixation ability of the nitrogenase complex, which is inactivated in the presence of CO.


ensembl_gene_id: RGE_22960
symbol: flgH-2
gene_biotype: protein_coding
description:
  Putative flagellar L-ring protein FlgH; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.


ensembl_gene_id: RGE_23000
symbol: nrdJ
gene_biotype: protein_coding
description:
  Vitamin B12-dependent ribonucleoside-diphosphate reductase NrdJ; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.


ensembl_gene_id: RGE_23020
symbol: blc
gene_biotype: protein_coding
description:
  Outer membrane lipoprotein Blc; Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.


ensembl_gene_id: RGE_23130
symbol: citC
gene_biotype: protein_coding
description:
  Citrate lyase synthetase CitC; Acetylation of prosthetic group (2-(5''-phosphoribosyl)-3'- dephosphocoenzyme-A) of the gamma subunit of citrate lyase.


ensembl_gene_id: RGE_23560
symbol: otsB
gene_biotype: protein_coding
description:
  Trehalose-phosphatase protein OtsB; Removes the phosphate from trehalose 6-phosphate to produce free trehalose.


ensembl_gene_id: RGE_23620
symbol: folD
gene_biotype: protein_coding
description:
  Bifunctional protein FolD; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.


ensembl_gene_id: RGE_23660
symbol: aceF
gene_biotype: protein_coding
description:
  Dihydrolipoamide acetyltransferase AceF; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


ensembl_gene_id: RGE_23680
symbol: hip
gene_biotype: protein_coding
description:
  High potential iron-sulfur protein, HiPIP; Specific class of high-redox-potential 4Fe-4S ferredoxins. Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria; Belongs to the high-potential iron-sulfur protein (HiPIP) family.


ensembl_gene_id: RGE_23750
symbol: phbC-2
gene_biotype: protein_coding
description:
  Protein synonym:poly(3-hydroxyalkanoate) polymerase; protein synonym:poly(3-hydroxybutyrate) polymerase; protein synonym:polyhydroxyalkanoic acid synthase.


ensembl_gene_id: RGE_23810
symbol: selU
gene_biotype: protein_coding
description:
  tRNA 2-selenouridine synthase; Protein synonym:selenophosphate-dependent tRNA 2-selenouridine synthase; Belongs to the SelU family.


ensembl_gene_id: RGE_23820
symbol: glnD
gene_biotype: protein_coding
description:
  UTP-GlnB uridylyltransferase, GlnD; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen fixation and metabolism.


ensembl_gene_id: RGE_23840
symbol: purL
gene_biotype: protein_coding
description:
  Phosphoribosylformylglycinamidine synthase PurL; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.


ensembl_gene_id: RGE_23930
symbol: msrA
gene_biotype: protein_coding
description:
  Peptide methionine sulfoxide reductase MsrA; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.


ensembl_gene_id: RGE_23970
symbol: lexA
gene_biotype: protein_coding
description:
  LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.


ensembl_gene_id: RGE_24030
symbol: dapE
gene_biotype: protein_coding
description:
  Succinyl-diaminopimelate desuccinylase DapE; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily.


ensembl_gene_id: RGE_24050
symbol: dapD
gene_biotype: protein_coding
description:
  2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase DapD; Belongs to the transferase hexapeptide repeat family.


ensembl_gene_id: RGE_24090
symbol: queF
gene_biotype: protein_coding
description:
  NADPH-dependent 7-cyano-7-deazaguanine reductase QueF; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.


ensembl_gene_id: RGE_24100
symbol: smc
gene_biotype: protein_coding
description:
  Chromosome partition protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family.


ensembl_gene_id: RGE_24120
symbol: ligA
gene_biotype: protein_coding
description:
  NAD-dependent DNA ligase LigA; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily.


ensembl_gene_id: RGE_24250
symbol: rhlE-2
gene_biotype: protein_coding
description:
  ATP-dependent RNA helicase RhlE; DEAD-box RNA helicase involved in ribosome assembly. Has RNA- dependent ATPase activity and unwinds double-stranded RNA.


ensembl_gene_id: RGE_24290
symbol: ispZ
gene_biotype: protein_coding
description:
  Putative intracellular septation protein; Involved in cell division; probably involved in intracellular septation; Belongs to the YciB family.


ensembl_gene_id: RGE_24300
symbol: msrB
gene_biotype: protein_coding
description:
  Protein synonym:peptide-methionine (R)-S-oxide reductase; Belongs to the MsrB Met sulfoxide reductase family.


ensembl_gene_id: RGE_24310
symbol: selO
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation). Belongs to the SELO family.


ensembl_gene_id: RGE_24320
symbol: RGE_24320
gene_biotype: protein_coding
description:
  Putative ABC transporter permease; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: RGE_24380
symbol: RGE_24380
gene_biotype: protein_coding
description:
  3-hydroxyacyl-CoA dehydrogenase / short chain enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: RGE_24450
symbol: RGE_24450
gene_biotype: protein_coding
description:
  Short-chain dehydrogenase/reductase SDR; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: RGE_24460
symbol: ribB
gene_biotype: protein_coding
description:
  3,4-dihydroxy-2-butanone 4-phosphate synthase RibB; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.


ensembl_gene_id: RGE_24500
symbol: mdoG
gene_biotype: protein_coding
description:
  Periplasmic glucan biosynthesis protein MdoG; Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).


ensembl_gene_id: RGE_24520
symbol: thrS
gene_biotype: protein_coding
description:
  threonyl-tRNA synthetase ThrS; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).


ensembl_gene_id: RGE_24530
symbol: infC
gene_biotype: protein_coding
description:
  Translation initiation factor IF-3 InfC; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.


ensembl_gene_id: RGE_24550
symbol: rplT
gene_biotype: protein_coding
description:
  50S ribosomal protein L20 RplT; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.


ensembl_gene_id: RGE_24560
symbol: pheS
gene_biotype: protein_coding
description:
  phenylalanyl-tRNA synthetase alpha chain PheS; Protein synonym:phenylalanine--tRNA ligase alpha chain; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.


ensembl_gene_id: RGE_24570
symbol: pheT
gene_biotype: protein_coding
description:
  phenylalanyl-tRNA synthetase beta chain PheT; Protein synonym:phenylalanine--tRNA ligase beta chain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.


ensembl_gene_id: RGE_24580
symbol: ihfA
gene_biotype: protein_coding
description:
  Integration host factor subunit alpha IhfA; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.


ensembl_gene_id: RGE_25170
symbol: rpoN
gene_biotype: protein_coding
description:
  RNA polymerase sigma-54 factor RpoN; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.


ensembl_gene_id: RGE_25250
symbol: RGE_25250
gene_biotype: protein_coding
description:
  Anaerobic sulfatase-maturating enzyme; Protein synonym:Ser-type sulfatase-activating enzyme; protein synonym:arylsulfatase-activating protein.


ensembl_gene_id: RGE_25330
symbol: tauB
gene_biotype: protein_coding
description:
  Taurine ABC transporter ATP binding protein TauB; Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Taurine importer (TC 3.A.1.17.1) family.


ensembl_gene_id: RGE_25400
symbol: ssuD
gene_biotype: protein_coding
description:
  Alkanesulfonate monooxygenase SsuD; Catalyzes the desulfonation of aliphatic sulfonates. Belongs to the SsuD family.


ensembl_gene_id: RGE_25420
symbol: ssuB
gene_biotype: protein_coding
description:
  Aliphatic sulfonate import ATP-binding protein SsuB; Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system.


ensembl_gene_id: RGE_25440
symbol: nifD
gene_biotype: protein_coding
description:
  Putative nitrogenase molybdenum-iron protein alpha chain NifD; Belongs to the NifD/NifK/NifE/NifN family.


ensembl_gene_id: RGE_26090
symbol: tmk
gene_biotype: protein_coding
description:
  Thymidylate kinase Tmk; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.


ensembl_gene_id: RGE_26100
symbol: mltG
gene_biotype: protein_coding
description:
  Hypothetical protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.


ensembl_gene_id: RGE_26220
symbol: RGE_26220
gene_biotype: protein_coding
description:
  Beta-alanine-pyruvate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: RGE_26250
symbol: puuA
gene_biotype: protein_coding
description:
  Glutamate--putrescine ligase PuuA; Protein synonym:gamma-glutamylputrescine synthetase; Belongs to the glutamine synthetase family.


ensembl_gene_id: RGE_26260
symbol: spuC
gene_biotype: protein_coding
description:
  Putative aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: RGE_26270
symbol: potF
gene_biotype: protein_coding
description:
  Putrescine ABC transporter substrate-binding protein PotF; Required for the activity of the bacterial periplasmic transport system of putrescine; Belongs to the bacterial solute-binding protein PotD/PotF family.


ensembl_gene_id: RGE_26280
symbol: potG
gene_biotype: protein_coding
description:
  Putrescine ABC transporter ATP-binding protein PotG; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.


ensembl_gene_id: RGE_26330
symbol: glnA-2
gene_biotype: protein_coding
description:
  Glutamine synthetase GlnA; Protein synonym:glutamate--ammonia ligase; Belongs to the glutamine synthetase family.


ensembl_gene_id: RGE_26370
symbol: mtnA
gene_biotype: protein_coding
description:
  Putative translation initiation factor, aIF-2BI/5-methylthioribose-1-phosphate isomerase MtnA; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).


ensembl_gene_id: RGE_26380
symbol: mtaP
gene_biotype: protein_coding
description:
  Methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.


ensembl_gene_id: RGE_26390
symbol: dusA
gene_biotype: protein_coding
description:
  tRNA-dihydrouridine synthase A DusA; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily.


ensembl_gene_id: RGE_26840
symbol: relA
gene_biotype: protein_coding
description:
  GTP pyrophosphokinase RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.


ensembl_gene_id: RGE_26900
symbol: ispF
gene_biotype: protein_coding
description:
  2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase IspF; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).


ensembl_gene_id: RGE_26910
symbol: ispD
gene_biotype: protein_coding
description:
  2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase IspD; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).


ensembl_gene_id: RGE_26920
symbol: mfd
gene_biotype: protein_coding
description:
  Transcription-repair-coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.


ensembl_gene_id: RGE_26940
symbol: trpB-2
gene_biotype: protein_coding
description:
  Putative tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.


ensembl_gene_id: RGE_27000
symbol: yggX
gene_biotype: protein_coding
description:
  Fe(II) trafficking protein YggX; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.


ensembl_gene_id: RGE_27040
symbol: dnaG
gene_biotype: protein_coding
description:
  DNA primase DnaG; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.


ensembl_gene_id: RGE_27060
symbol: rpoD
gene_biotype: protein_coding
description:
  RNA polymerase primary sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.


ensembl_gene_id: RGE_27090
symbol: hemH
gene_biotype: protein_coding
description:
  Ferrochelatase HemH; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.


ensembl_gene_id: RGE_27110
symbol: grpE
gene_biotype: protein_coding
description:
  Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...]


ensembl_gene_id: RGE_27130
symbol: dnaJ
gene_biotype: protein_coding
description:
  Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]


ensembl_gene_id: RGE_27160
symbol: dnaB
gene_biotype: protein_coding
description:
  Replicative DNA helicase DnaB; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily.


ensembl_gene_id: RGE_27180
symbol: rpsR
gene_biotype: protein_coding
description:
  30S ribosomal protein S18 RpsR; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.


ensembl_gene_id: RGE_27190
symbol: priB
gene_biotype: protein_coding
description:
  Primosomal replication protein N PriB; Binds single-stranded DNA at the primosome assembly site (PAS); Belongs to the PriB family.


ensembl_gene_id: RGE_27220
symbol: ppsA
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate synthase PpsA; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.


ensembl_gene_id: RGE_27230
symbol: RGE_27230
gene_biotype: protein_coding
description:
  Putative phosphotransferase; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.


ensembl_gene_id: RGE_27260
symbol: lpxB
gene_biotype: protein_coding
description:
  lipid-A-disaccharide synthase LpxB; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: RGE_27270
symbol: lpxA
gene_biotype: protein_coding
description:
  acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase LpxA; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: RGE_27280
symbol: fabZ
gene_biotype: protein_coding
description:
  (3R)-hydroxymyristoyl-ACP dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.


ensembl_gene_id: RGE_27290
symbol: lpxD
gene_biotype: protein_coding
description:
  UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily.


ensembl_gene_id: RGE_27310
symbol: yaeT
gene_biotype: protein_coding
description:
  Outer membrane protein assembly factor YaeT; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: RGE_27330
symbol: dxr
gene_biotype: protein_coding
description:
  1-deoxy-D-xylulose 5-phosphate reductoisomerase Dxr; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family.


ensembl_gene_id: RGE_27350
symbol: uppS
gene_biotype: protein_coding
description:
  Undecaprenyl pyrophosphate synthetase UppS; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.


ensembl_gene_id: RGE_27360
symbol: rrf
gene_biotype: protein_coding
description:
  Ribosome recycling factor Rrf; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.


ensembl_gene_id: RGE_27380
symbol: tsf
gene_biotype: protein_coding
description:
  Elongation factor EF-Ts Tsf; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.


ensembl_gene_id: RGE_27420
symbol: nnrD
gene_biotype: protein_coding
description:
  Hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.  Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epi [...]


ensembl_gene_id: RGE_27430
symbol: rnr
gene_biotype: protein_coding
description:
  Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.


ensembl_gene_id: RGE_27450
symbol: purA
gene_biotype: protein_coding
description:
  Adenylosuccinate synthetase PurA; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.


ensembl_gene_id: RGE_27460
symbol: hisZ
gene_biotype: protein_coding
description:
  ATP phosphoribosyltransferase regulatory subunit HisZ; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.


ensembl_gene_id: RGE_27500
symbol: hflX
gene_biotype: protein_coding
description:
  GTP-binding protein HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.


ensembl_gene_id: RGE_27510
symbol: hfq
gene_biotype: protein_coding
description:
  Protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.


ensembl_gene_id: RGE_27520
symbol: engA
gene_biotype: protein_coding
description:
  GTP-binding protein EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.


ensembl_gene_id: RGE_27530
symbol: bamB
gene_biotype: protein_coding
description:
  Hypothetical protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: RGE_27560
symbol: ispG
gene_biotype: protein_coding
description:
  4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase IspG; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family.


ensembl_gene_id: RGE_27590
symbol: rlmN
gene_biotype: protein_coding
description:
  Ribosomal RNA large subunit methyltransferase N; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family.


ensembl_gene_id: RGE_27600
symbol: ndk
gene_biotype: protein_coding
description:
  Nucleoside diphosphate kinase Ndk; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.


ensembl_gene_id: RGE_27610
symbol: rluB
gene_biotype: protein_coding
description:
  Ribosomal large subunit pseudouridine synthase B RluB; Belongs to the pseudouridine synthase RsuA family.


ensembl_gene_id: RGE_27620
symbol: scpB
gene_biotype: protein_coding
description:
  Segregation and condensation protein B; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.


ensembl_gene_id: RGE_27630
symbol: rluD
gene_biotype: protein_coding
description:
  Ribosomal large subunit pseudouridine synthase D RluD; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.


ensembl_gene_id: RGE_27640
symbol: bamD
gene_biotype: protein_coding
description:
  Putative lipoprotein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: RGE_27740
symbol: odhB
gene_biotype: protein_coding
description:
  2-oxoglutarate dehydrogenase E2 component OdhB; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).


ensembl_gene_id: RGE_27840
symbol: macA
gene_biotype: protein_coding
description:
  Macrolide-specific efflux protein MacA; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: RGE_27850
symbol: macB
gene_biotype: protein_coding
description:
  Macrolide ABC transporter permease/ATP-binding protein MacB; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP- binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.


ensembl_gene_id: RGE_27920
symbol: lon
gene_biotype: protein_coding
description:
  ATP-dependent protease La, Lon; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.


ensembl_gene_id: RGE_27930
symbol: clpX
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.


ensembl_gene_id: RGE_27950
symbol: tig
gene_biotype: protein_coding
description:
  Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.


ensembl_gene_id: RGE_28020
symbol: pbpG
gene_biotype: protein_coding
description:
  D-alanyl-D-alanine endopeptidase, PbpG; Protein synonym:penicillin-binding protein 7; Belongs to the peptidase S11 family.


ensembl_gene_id: RGE_28030
symbol: leuA-2
gene_biotype: protein_coding
description:
  2-isopropylmalate synthase,LeuA; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.


ensembl_gene_id: RGE_28050
symbol: ilvC
gene_biotype: protein_coding
description:
  Ketol-acid reductoisomerase IlvC; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.


ensembl_gene_id: RGE_28120
symbol: dgkA
gene_biotype: protein_coding
description:
  Diacylglycerol kinase DgkA; Recycling of diacylglycerol produced during the turnover of membrane phospholipid.


ensembl_gene_id: RGE_28150
symbol: nadE
gene_biotype: protein_coding
description:
  NAD synthetase NadE; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.


ensembl_gene_id: RGE_28170
symbol: ppa
gene_biotype: protein_coding
description:
  Inorganic diphosphatase Ppa; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.


ensembl_gene_id: RGE_28180
symbol: hppA
gene_biotype: protein_coding
description:
  Pyrophosphate-energized proton pump HppA; Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.


ensembl_gene_id: RGE_28220
symbol: truB
gene_biotype: protein_coding
description:
  tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.


ensembl_gene_id: RGE_28230
symbol: rbfA
gene_biotype: protein_coding
description:
  Ribosome-binding factor A RbfA; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.


ensembl_gene_id: RGE_28240
symbol: infB
gene_biotype: protein_coding
description:
  Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.


ensembl_gene_id: RGE_28250
symbol: nusA
gene_biotype: protein_coding
description:
  Transcription termination factor NusA; Participates in both transcription termination and antitermination.


ensembl_gene_id: RGE_28260
symbol: rimP
gene_biotype: protein_coding
description:
  Ribosome maturation factor RimP; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.


ensembl_gene_id: RGE_28550
symbol: fumC
gene_biotype: protein_coding
description:
  Fumarate hydratase class II FumC; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.


ensembl_gene_id: RGE_28720
symbol: pucB
gene_biotype: protein_coding
description:
  Light-harvesting protein B-800/850 beta chain PucB; Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers.


ensembl_gene_id: RGE_28900
symbol: cobD
gene_biotype: protein_coding
description:
  Putative cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.


ensembl_gene_id: RGE_29070
symbol: glgC
gene_biotype: protein_coding
description:
  Glucose-1-phosphate adenylyltransferase GlgC; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.


ensembl_gene_id: RGE_29080
symbol: glgP
gene_biotype: protein_coding
description:
  Glycogen phosphorylase GlgP; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.


ensembl_gene_id: RGE_29090
symbol: glgB-2
gene_biotype: protein_coding
description:
  1,4-alpha-glucan branching enzyme GlgB; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.


ensembl_gene_id: RGE_29140
symbol: pepA
gene_biotype: protein_coding
description:
  Putative cytosol aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.


ensembl_gene_id: RGE_29170
symbol: cbiX
gene_biotype: protein_coding
description:
  Cobalamin (Vitamin B12) biosynthesis CbiX protein; Protein synonym:sirohydrochlorin cobaltochelatase.


ensembl_gene_id: RGE_29300
symbol: nikR
gene_biotype: protein_coding
description:
  Putative nickel-responsive regulator; Transcriptional regulator; Belongs to the transcriptional regulatory CopG/NikR family.


ensembl_gene_id: RGE_29610
symbol: RGE_29610
gene_biotype: protein_coding
description:
  Heavy metal efflux pump, CzcA family; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: RGE_29730
symbol: RGE_29730
gene_biotype: protein_coding
description:
  Acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: RGE_30770
symbol: RGE_30770
gene_biotype: protein_coding
description:
  Hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.


ensembl_gene_id: RGE_30860
symbol: metQ
gene_biotype: protein_coding
description:
  D-methionine ABC transporter substrate binding protein MetQ; Belongs to the nlpA lipoprotein family.


ensembl_gene_id: RGE_30870
symbol: metN
gene_biotype: protein_coding
description:
  D-methionine ABC transporter ATP binding protein MetN; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.


ensembl_gene_id: RGE_30970
symbol: guaB
gene_biotype: protein_coding
description:
  Inosine-5'-monophosphate dehydrogenase GuaB; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.


ensembl_gene_id: RGE_31010
symbol: smpB
gene_biotype: protein_coding
description:
  SsrA-binding protein SmpB; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switch [...]


ensembl_gene_id: RGE_31050
symbol: rimO
gene_biotype: protein_coding
description:
  MiaB-like tRNA modifying enzyme YliG; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily.


ensembl_gene_id: RGE_31250
symbol: cysQ
gene_biotype: protein_coding
description:
  3'(2'),5'-bisphosphate nucleotidase CysQ; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family.


ensembl_gene_id: RGE_31270
symbol: cysNC
gene_biotype: protein_coding
description:
  Sulfate adenylyltransferase subunit 1/adenylyl-sulfate kinase CysN/CysC; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.


ensembl_gene_id: RGE_31280
symbol: ahpC
gene_biotype: protein_coding
description:
  Alkyl hydroperoxide reductase subunit C AhpC; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.


ensembl_gene_id: RGE_31440
symbol: phnX
gene_biotype: protein_coding
description:
  Phosphonoacetaldehyde hydrolase PhnX; Involved in phosphonate degradation; Belongs to the HAD-like hydrolase superfamily. PhnX family.


ensembl_gene_id: RGE_31460
symbol: phnW
gene_biotype: protein_coding
description:
  2-aminoethylphosphonate-pyruvate transaminase PhnW; Involved in phosphonate degradation; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.


ensembl_gene_id: RGE_31610
symbol: tilS
gene_biotype: protein_coding
description:
  tRNA(Ile)-lysidine synthase TilS; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.


ensembl_gene_id: RGE_31620
symbol: accA-2
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase, carboxyl transferase, alpha subunit AccA; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.


ensembl_gene_id: RGE_31660
symbol: ppiA
gene_biotype: protein_coding
description:
  Peptidyl-prolyl cis-trans isomerase A (cyclophilin A) PpiA; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.


ensembl_gene_id: RGE_31670
symbol: ppiB
gene_biotype: protein_coding
description:
  Peptidyl-prolyl cis-trans isomerase B (cyclophilin B) PpiB; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.


ensembl_gene_id: RGE_31680
symbol: lpxH
gene_biotype: protein_coding
description:
  UDP-2,3-diacylglucosamine hydrolase LpxH; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: RGE_31700
symbol: clpA
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease; Protein synonym:ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family.


ensembl_gene_id: RGE_31710
symbol: clpS
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease adapter protein ClpS; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family.


ensembl_gene_id: RGE_31850
symbol: hemN
gene_biotype: protein_coding
description:
  Oxygen-independent coproporphyrinogen III oxidase HemN; Belongs to the anaerobic coproporphyrinogen-III oxidase family.


ensembl_gene_id: RGE_31900
symbol: ccoP
gene_biotype: protein_coding
description:
  Cbb3-type cytochrome oxidase subunit 3 CcoP; C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.


ensembl_gene_id: RGE_31970
symbol: xseA/sodB
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease 7 large subunit/superoxide dismutase; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family.


ensembl_gene_id: RGE_32000
symbol: lpxK
gene_biotype: protein_coding
description:
  Tetraacyldisaccharide 4'-kinase LpxK; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).


ensembl_gene_id: RGE_32020
symbol: kdsB
gene_biotype: protein_coding
description:
  3-deoxy-manno-octulosonate cytidylyltransferase (CMP-KDO synthetase) KdsB; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.


ensembl_gene_id: RGE_32030
symbol: adk
gene_biotype: protein_coding
description:
  Adenylate kinase Adk; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.


ensembl_gene_id: RGE_32130
symbol: tadA
gene_biotype: protein_coding
description:
  CMP/dCMP deaminase zinc-binding; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.


ensembl_gene_id: RGE_32270
symbol: RGE_32270
gene_biotype: protein_coding
description:
  Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.


ensembl_gene_id: RGE_32330
symbol: cpdB
gene_biotype: protein_coding
description:
  2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase CpdB; Bifunctional protein; Belongs to the 5'-nucleotidase family.


ensembl_gene_id: RGE_32360
symbol: rraA
gene_biotype: protein_coding
description:
  Regulator of ribonuclease activity A RraA; Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.


ensembl_gene_id: RGE_32420
symbol: nadA
gene_biotype: protein_coding
description:
  Quinolinate synthetase NadA; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.


ensembl_gene_id: RGE_32530
symbol: clpB
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease ATP-binding subunit ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.


ensembl_gene_id: RGE_32570
symbol: moeA
gene_biotype: protein_coding
description:
  Molybdopterin biosynthesis protein MoeA; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.


ensembl_gene_id: RGE_32680
symbol: moaA
gene_biotype: protein_coding
description:
  Molybdenum cofactor biosynthesis protein A MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.


ensembl_gene_id: RGE_32690
symbol: mobA
gene_biotype: protein_coding
description:
  Putative molybdopterin-guanine dinucleotide biosynthesis protein A MobA; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family.


ensembl_gene_id: RGE_32750
symbol: gloB
gene_biotype: protein_coding
description:
  Hydroxyacylglutathione hydrolase GloB; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.


ensembl_gene_id: RGE_32780
symbol: upp
gene_biotype: protein_coding
description:
  Uracil phosphoribosyltransferase Upp; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.


ensembl_gene_id: RGE_32790
symbol: rlmB-2
gene_biotype: protein_coding
description:
  RNA methyltransferase, TrmH family, group 3; Specifically methylates the ribose of guanosine 2251 in 23S rRNA.


ensembl_gene_id: RGE_32980
symbol: recR
gene_biotype: protein_coding
description:
  Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.


ensembl_gene_id: RGE_32990
symbol: RGE_32990
gene_biotype: protein_coding
description:
  Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.


ensembl_gene_id: RGE_33000
symbol: dnaX
gene_biotype: protein_coding
description:
  DNA polymerase III gamma/tau subunit DnaX; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.


ensembl_gene_id: RGE_33010
symbol: purM
gene_biotype: protein_coding
description:
  Putative phosphoribosylformylglycinamidine cyclo-ligase PurM; Protein synonym:aminoimidazole ribonucleotide synthetase.


ensembl_gene_id: RGE_33100
symbol: rho
gene_biotype: protein_coding
description:
  Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.


ensembl_gene_id: RGE_33160
symbol: pstB
gene_biotype: protein_coding
description:
  Phosphate ABC transporter ATP binding protein, PstB; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.


ensembl_gene_id: RGE_33180
symbol: pstC
gene_biotype: protein_coding
description:
  Phosphate ABC transporter permease PstC; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: RGE_33190
symbol: pstS
gene_biotype: protein_coding
description:
  Phosphate ABC transporter substrate binding protein PstS; Part of the ABC transporter complex PstSACB involved in phosphate import; Belongs to the PstS family.


ensembl_gene_id: RGE_33210
symbol: glmM
gene_biotype: protein_coding
description:
  Phosphoglucosamine mutase GlmM; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.


ensembl_gene_id: RGE_33220
symbol: folP
gene_biotype: protein_coding
description:
  Dihydropteroate synthase FolP; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.


ensembl_gene_id: RGE_33230
symbol: ftsH
gene_biotype: protein_coding
description:
  ATP-dependent zinc metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family.  In the central section; belongs to the AAA ATPase family.


ensembl_gene_id: RGE_33250
symbol: rrmJ
gene_biotype: protein_coding
description:
  Ribosomal RNA large subunit methyltransferase J; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.


ensembl_gene_id: RGE_33280
symbol: greA
gene_biotype: protein_coding
description:
  Transcription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.


ensembl_gene_id: RGE_33320
symbol: rumA
gene_biotype: protein_coding
description:
  23S rRNA (uracil-5-)-methyltransferase RumA; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.


ensembl_gene_id: RGE_33330
symbol: rpoS
gene_biotype: protein_coding
description:
  RNA polymerase sigma factor RpoS; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.


ensembl_gene_id: RGE_33360
symbol: surE
gene_biotype: protein_coding
description:
  Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.


ensembl_gene_id: RGE_33400
symbol: RGE_33400
gene_biotype: protein_coding
description:
  PucC family protein; Protein synonym:ORF440 protein; similar to ORF428 product of Rhodobacter capsulatus.


ensembl_gene_id: RGE_33460
symbol: bchN
gene_biotype: protein_coding
description:
  Light-independent protochlorophyllide reductase subunit N; Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex.


ensembl_gene_id: RGE_33470
symbol: bchB
gene_biotype: protein_coding
description:
  Light-independent protochlorophyllide reductase subunit B; Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex.


ensembl_gene_id: RGE_33490
symbol: bchL
gene_biotype: protein_coding
description:
  Light-independent protochlorophyllide reductase iron-sulfur ATP-binding protein; Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The L component serves as a unique electron donor to the NB-component of the complex, and binds Mg-ATP.


ensembl_gene_id: RGE_33550
symbol: acsF
gene_biotype: protein_coding
description:
  Magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase AcsF; Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis in aerobic conditions. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13- monomethyl ester (MgPMME) (By similarity); Belongs to the AcsF family.


ensembl_gene_id: RGE_33610
symbol: pufC
gene_biotype: protein_coding
description:
  Photosynthesis reaction center complex, subunit C PufC; The reaction center of purple bacteria contains a tightly bound cytochrome molecule which re-reduces the photo oxidized primary electron donor.


ensembl_gene_id: RGE_33620
symbol: pufM
gene_biotype: protein_coding
description:
  Photosynthesis reaction center complex, M subunit PufM; The reaction center is a membrane-bound complex that mediates the initial photochemical event in the electron transfer process of photosynthesis.


ensembl_gene_id: RGE_33630
symbol: pufL
gene_biotype: protein_coding
description:
  Photosynthesis reaction center complex, L subunit PufL; The reaction center is a membrane-bound complex that mediates the initial photochemical event in the electron transfer process of photosynthesis.


ensembl_gene_id: RGE_33640
symbol: pufA
gene_biotype: protein_coding
description:
  Alpha subunit of light-harvesting 1 (B870) complex PufA; Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers.


ensembl_gene_id: RGE_33650
symbol: RGE_33650
gene_biotype: protein_coding
description:
  Antenna complex, beta subunit family protein; Previously called ORF2 of Rubrivivax gelatinosus puf operon; protein synonym:ORF74.


ensembl_gene_id: RGE_33660
symbol: pufB
gene_biotype: protein_coding
description:
  Beta subunit of light-harvesting 1 (B870) complex PufB; Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers.


ensembl_gene_id: RGE_33670
symbol: RGE_33670
gene_biotype: protein_coding
description:
  Hypothetical soluble protein; Previously called ORF1 of Rubrivivax gelatinosus puf operon; protein synonym:ORF48; small protein with high pI.


ensembl_gene_id: RGE_33680
symbol: bchZ
gene_biotype: protein_coding
description:
  Bacteriochlorophyllide reductase subunit BchZ; Converts chlorophylls (Chl) into bacteriochlorophylls (BChl) by reducing ring B of the tetrapyrrole; Belongs to the ChlB/BchB/BchZ family.


ensembl_gene_id: RGE_33780
symbol: RGE_33780
gene_biotype: protein_coding
description:
  HemN C-terminal domain containing protein; Protein synonym:ORF468; Belongs to the anaerobic coproporphyrinogen-III oxidase family.


ensembl_gene_id: RGE_33800
symbol: menA
gene_biotype: protein_coding
description:
  1,4-Dihydroxy-2-naphtoate prenyltransferase MenA; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily.


ensembl_gene_id: RGE_33860
symbol: ppk-2
gene_biotype: protein_coding
description:
  Polyphosphate kinase Ppk; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).


ensembl_gene_id: RGE_33870
symbol: polA
gene_biotype: protein_coding
description:
  DNA polymerase I PolA; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.


ensembl_gene_id: RGE_33930
symbol: guaC
gene_biotype: protein_coding
description:
  GMP reductase GuaC; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides; Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.


ensembl_gene_id: RGE_33960
symbol: valS
gene_biotype: protein_coding
description:
  valyl-tRNA synthetase ValS; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.


ensembl_gene_id: RGE_33970
symbol: RGE_33970
gene_biotype: protein_coding
description:
  Putative phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: RGE_34080
symbol: livM
gene_biotype: protein_coding
description:
  Putative high-affinity branched-chain amino acid ABC transporter permease LivM; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: RGE_34090
symbol: livH
gene_biotype: protein_coding
description:
  Putative high-affinity branched-chain amino acid ABC transporter permease LivH; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: RGE_34120
symbol: lolA
gene_biotype: protein_coding
description:
  Outer membrane lipoproteins carrier protein LolA; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).


ensembl_gene_id: RGE_34140
symbol: crp
gene_biotype: protein_coding
description:
  Transcriptional regulator, Crp/Fnr family; Protein synonym:cAMP receptor protein; protein synonym:cAMP regulatory protein.


ensembl_gene_id: RGE_34190
symbol: RGE_34190
gene_biotype: protein_coding
description:
  Fmu (Sun) domain protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.


ensembl_gene_id: RGE_34200
symbol: purN
gene_biotype: protein_coding
description:
  Phosphoribosylglycinamide formyltransferase PurN; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.


ensembl_gene_id: RGE_34210
symbol: trpS
gene_biotype: protein_coding
description:
  tryptophanyl-tRNA synthetase TrpS; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: RGE_34430
symbol: RGE_34430
gene_biotype: protein_coding
description:
  Methyl-accepting chemotaxis sensory transducer with Pas/Pac sensor; Protein synonym:putative aerotaxis receptor.


ensembl_gene_id: RGE_34450
symbol: gloA-2
gene_biotype: protein_coding
description:
  Lactoylglutathione lyase GloA; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.


ensembl_gene_id: RGE_34460
symbol: eda
gene_biotype: protein_coding
description:
  2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase Eda; Bifunctional protein.


ensembl_gene_id: RGE_34470
symbol: edd
gene_biotype: protein_coding
description:
  Phosphogluconate dehydratase Edd; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family.


ensembl_gene_id: RGE_34480
symbol: RGE_34480
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.


ensembl_gene_id: RGE_34500
symbol: pdxH
gene_biotype: protein_coding
description:
  Pyridoxine/pyridoxamine 5'-phosphate oxidase PdxH; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).


ensembl_gene_id: RGE_34730
symbol: parC
gene_biotype: protein_coding
description:
  Topoisomerase IV subunit A ParC; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.


ensembl_gene_id: RGE_34760
symbol: parE
gene_biotype: protein_coding
description:
  Topoisomerase IV subunit B ParE; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily.


ensembl_gene_id: RGE_34810
symbol: dapA
gene_biotype: protein_coding
description:
  Dihydrodipicolinate synthase DapA; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).


ensembl_gene_id: RGE_34870
symbol: dut
gene_biotype: protein_coding
description:
  Deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.


ensembl_gene_id: RGE_34880
symbol: coaBC
gene_biotype: protein_coding
description:
  Phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase CoaB/CoaC; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.


ensembl_gene_id: RGE_34910
symbol: alaS
gene_biotype: protein_coding
description:
  alanyl-tRNA synthetase AlaS; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.


ensembl_gene_id: RGE_34940
symbol: gabT
gene_biotype: protein_coding
description:
  4-aminobutyrate aminotransferase GabT; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: RGE_34950
symbol: potA
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein PotA; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.


ensembl_gene_id: RGE_35020
symbol: trmB
gene_biotype: protein_coding
description:
  tRNA (guanine-N(7)-)-methyltransferase TrmB; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.


ensembl_gene_id: RGE_35030
symbol: uppP
gene_biotype: protein_coding
description:
  Undecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.


ensembl_gene_id: RGE_35080
symbol: waaA
gene_biotype: protein_coding
description:
  3-deoxy-D-manno-octulosonic-acid transferase WaaA; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.


ensembl_gene_id: RGE_35110
symbol: ada/alkA
gene_biotype: protein_coding
description:
  DNA-O6-methylguanine-protein-cysteine S-methyltransferase/DNA-3-methyladenine glycosylase Ada/AlkA; Bifunctional protein, transcriptional regulator Ada.


ensembl_gene_id: RGE_35120
symbol: RGE_35120
gene_biotype: protein_coding
description:
  Putative methylated-DNA--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.


ensembl_gene_id: RGE_35290
symbol: katG
gene_biotype: protein_coding
description:
  Peroxidase/catalase KatG; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily.


ensembl_gene_id: RGE_35310
symbol: serS
gene_biotype: protein_coding
description:
  seryl-tRNA synthetase SerS; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).


ensembl_gene_id: RGE_35320
symbol: ispH
gene_biotype: protein_coding
description:
  4-hydroxy-3-methylbut-2-enyl diphosphate reductase IspH; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.


ensembl_gene_id: RGE_35420
symbol: cheR
gene_biotype: protein_coding
description:
  Chemotaxis protein methyltransferase CheR; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.


ensembl_gene_id: RGE_35430
symbol: cheD
gene_biotype: protein_coding
description:
  Chemoreceptor glutamine deamidase CheD; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.


ensembl_gene_id: RGE_35440
symbol: cheB
gene_biotype: protein_coding
description:
  Protein-glutamate methylesterase CheB; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.


ensembl_gene_id: RGE_35460
symbol: hemN-2
gene_biotype: protein_coding
description:
  Oxygen-independent coproporphyrinogen III oxidase HemN; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.


ensembl_gene_id: RGE_35470
symbol: RGE_35470
gene_biotype: protein_coding
description:
  Nucleoside-triphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.


ensembl_gene_id: RGE_35480
symbol: rph
gene_biotype: protein_coding
description:
  Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.


ensembl_gene_id: RGE_35530
symbol: dld
gene_biotype: protein_coding
description:
  D-lactate dehydrogenase Dld; Catalyzes the oxidation of D-lactate to pyruvate. Belongs to the quinone-dependent D-lactate dehydrogenase family.


ensembl_gene_id: RGE_35540
symbol: lldD
gene_biotype: protein_coding
description:
  L-lactate dehydrogenase cytochrome LldD; Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain; Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.


ensembl_gene_id: RGE_35560
symbol: lldP
gene_biotype: protein_coding
description:
  L-lactate permease LldP; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family.


ensembl_gene_id: RGE_35570
symbol: thiC
gene_biotype: protein_coding
description:
  Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.


ensembl_gene_id: RGE_35670
symbol: rpoZ
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase subunit omega RpoZ; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.


ensembl_gene_id: RGE_35700
symbol: spoT
gene_biotype: protein_coding
description:
  GTP pyrophosphokinase/guanosine-3',5'-bis (diphosphate) 3'-pyrophosphohydrolase SpoT; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.


ensembl_gene_id: RGE_35710
symbol: greB
gene_biotype: protein_coding
description:
  Transcription elongation factor GreB; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.


ensembl_gene_id: RGE_35720
symbol: RGE_35720
gene_biotype: protein_coding
description:
  Hypothetical protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.


ensembl_gene_id: RGE_35760
symbol: hupB-2
gene_biotype: protein_coding
description:
  Uptake hydrogenase large subunit HupB; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.


ensembl_gene_id: RGE_35870
symbol: hypA
gene_biotype: protein_coding
description:
  Hydrogenase nickel incorporation protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.


ensembl_gene_id: RGE_36060
symbol: cbbL
gene_biotype: protein_coding
description:
  Ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit CbbL; RuBisCO catalyzes two reactions: the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site; Belongs to the RuBisCO large chain family. Type I subfamily.


ensembl_gene_id: RGE_36310
symbol: pncB
gene_biotype: protein_coding
description:
  Nicotinate phosphoribosyltransferase PncB; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family.


ensembl_gene_id: RGE_36460
symbol: hemD
gene_biotype: protein_coding
description:
  uroporphyrinogen-III synthase HemD; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.


ensembl_gene_id: RGE_36470
symbol: hemC
gene_biotype: protein_coding
description:
  Porphobilinogen deaminase HemC; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.


ensembl_gene_id: RGE_36480
symbol: ppc
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate carboxylase Ppc; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family.


ensembl_gene_id: RGE_36520
symbol: dinP
gene_biotype: protein_coding
description:
  DNA-directed DNA polymerase DinP; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.


ensembl_gene_id: RGE_36700
symbol: RGE_36700
gene_biotype: protein_coding
description:
  Hypothetical protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.


ensembl_gene_id: RGE_36710
symbol: metG
gene_biotype: protein_coding
description:
  methionyl-tRNA synthetase MetG; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.


ensembl_gene_id: RGE_36790
symbol: scpA
gene_biotype: protein_coding
description:
  Segregation and condensation protein A ScpA; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.


ensembl_gene_id: RGE_37020
symbol: crp-2
gene_biotype: protein_coding
description:
  Catabolite gene activator; Protein synonym:cAMP receptor protein; protein synonym:cAMP regulatory protein.


ensembl_gene_id: RGE_37030
symbol: mtnN
gene_biotype: protein_coding
description:
  5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase MtnN; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.


ensembl_gene_id: RGE_37160
symbol: rimJ
gene_biotype: protein_coding
description:
  Ribosomal-protein-alanine acetyltransferase RimJ; Protein synonym:acetylating enzyme for N-terminal of ribosomal protein S5.


ensembl_gene_id: RGE_37240
symbol: menB
gene_biotype: protein_coding
description:
  Naphthoate synthase MenB; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA).


ensembl_gene_id: RGE_37280
symbol: phaC
gene_biotype: protein_coding
description:
  Putative K+/H+ antiporter subunit C PhaC; Protein synonym:pH adaptation potassium efflux system protein C.


ensembl_gene_id: RGE_37290
symbol: phaD
gene_biotype: protein_coding
description:
  Putative K+/H+ antiporter subunit D PhaD; Protein synonym:pH adaptation potassium efflux system protein D.


ensembl_gene_id: RGE_37300
symbol: phaE
gene_biotype: protein_coding
description:
  Putative K+/H+ antiporter subunit E PhaE; Protein synonym:pH adaptation potassium efflux system protein E.


ensembl_gene_id: RGE_37310
symbol: phaF
gene_biotype: protein_coding
description:
  Putative K+/H+ antiporter subunit F PhaF; Protein synonym:pH adaptation potassium efflux system protein F.


ensembl_gene_id: RGE_37320
symbol: phaG
gene_biotype: protein_coding
description:
  Putative K+/H+ antiporter subunit G PhaG; Protein synonym:pH adaptation potassium efflux system protein G.


ensembl_gene_id: RGE_37330
symbol: minE
gene_biotype: protein_coding
description:
  Cell division topological specificity factor MinE; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.


ensembl_gene_id: RGE_37350
symbol: minC
gene_biotype: protein_coding
description:
  Septum site-determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family.


ensembl_gene_id: RGE_37520
symbol: recC
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease V gamma chain RecC; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and [...]


ensembl_gene_id: RGE_37530
symbol: recB
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease V beta chain RecB; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and  [...]


ensembl_gene_id: RGE_37540
symbol: recD
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease V alpha chain RecD; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and [...]


ensembl_gene_id: RGE_37590
symbol: ku
gene_biotype: protein_coding
description:
  DNA end-binding protein Ku; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.


ensembl_gene_id: RGE_38020
symbol: infA-2
gene_biotype: protein_coding
description:
  Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.


ensembl_gene_id: RGE_38480
symbol: RGE_38480
gene_biotype: protein_coding
description:
  Hypothetical protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.


ensembl_gene_id: RGE_38490
symbol: rlmH
gene_biotype: protein_coding
description:
  Hypothetical protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family.


ensembl_gene_id: RGE_38500
symbol: rsfS
gene_biotype: protein_coding
description:
  Hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.


ensembl_gene_id: RGE_38510
symbol: nadD
gene_biotype: protein_coding
description:
  Nicotinate-nucleotide adenylyltransferase NadD; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).


ensembl_gene_id: RGE_38520
symbol: hemF
gene_biotype: protein_coding
description:
  Coproporphyrinogen III oxidase, aerobic HemF; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX.


ensembl_gene_id: RGE_38530
symbol: purD
gene_biotype: protein_coding
description:
  Phosphoribosylamine--glycine ligase PurD; Protein synonym:glycinamide ribonucleotide synthetase; protein synonym:phosphoribosylglycinamide synthetase; Belongs to the GARS family.


ensembl_gene_id: RGE_38960
symbol: glyA
gene_biotype: protein_coding
description:
  Serine hydroxymethyltransferase GlyA; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.


ensembl_gene_id: RGE_38970
symbol: nrdR
gene_biotype: protein_coding
description:
  Transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.


ensembl_gene_id: RGE_39040
symbol: ribD-2
gene_biotype: protein_coding
description:
  Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.


ensembl_gene_id: RGE_39060
symbol: ribBA
gene_biotype: protein_coding
description:
  3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.


ensembl_gene_id: RGE_39070
symbol: ribH
gene_biotype: protein_coding
description:
  6,7-dimethyl-8-ribityllumazine synthase RibH; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.


ensembl_gene_id: RGE_39080
symbol: nusB
gene_biotype: protein_coding
description:
  Transcription antitermination protein NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.


ensembl_gene_id: RGE_39110
symbol: tolQ
gene_biotype: protein_coding
description:
  Biopolymer transport protein, TolQ; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: RGE_39140
symbol: pcp
gene_biotype: protein_coding
description:
  Pyrrolidone-carboxylate peptidase Pcp; Removes 5-oxoproline from various penultimate amino acid residues except L-proline; Belongs to the peptidase C15 family.


ensembl_gene_id: RGE_39280
symbol: sodC
gene_biotype: protein_coding
description:
  Superoxide dismutase, Cu, Zn SodC; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family.


ensembl_gene_id: RGE_39460
symbol: add
gene_biotype: protein_coding
description:
  Adenosine deaminase Add; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.


ensembl_gene_id: RGE_39480
symbol: urtB
gene_biotype: protein_coding
description:
  Putative ABC transporter permease UrtB; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: RGE_39490
symbol: urtC
gene_biotype: protein_coding
description:
  ABC transporter permease UrtC; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: RGE_39750
symbol: ureD
gene_biotype: protein_coding
description:
  Urease accessory protein UreD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.


ensembl_gene_id: RGE_39870
symbol: RGE_39870
gene_biotype: protein_coding
description:
  5-hydroxyisourate hydrolase; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.


ensembl_gene_id: RGE_39980
symbol: guaD
gene_biotype: protein_coding
description:
  Guanine deaminase GuaD; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.


ensembl_gene_id: RGE_40250
symbol: mch
gene_biotype: protein_coding
description:
  Methenyltetrahydromethanopterin cyclohydrolase Mch; Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-formyl- H(4)MPT; Belongs to the MCH family.


ensembl_gene_id: RGE_40410
symbol: fhcD
gene_biotype: protein_coding
description:
  Formylmethanofuran--tetrahydromethanopterin N-formyltransferase FhcD; Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT); Belongs to the FTR family.


ensembl_gene_id: RGE_40520
symbol: pqqB
gene_biotype: protein_coding
description:
  Coenzyme PQQ biosynthesis protein B PqqB; May be involved in the transport of PQQ or its precursor to the periplasm; Belongs to the PqqB family.


ensembl_gene_id: RGE_40530
symbol: pqqC
gene_biotype: protein_coding
description:
  Coenzyme PQQ biosynthesis protein C PqqC; Ring cyclization and eight-electron oxidation of 3a-(2-amino- 2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9- dicarboxylic-acid to PQQ.


ensembl_gene_id: RGE_40540
symbol: pqqD
gene_biotype: protein_coding
description:
  Coenzyme PQQ synthesis D PqqD; Functions as a PqqA binding protein and presents PqqA to PqqE, in the pyrroloquinoline quinone (PQQ) biosynthetic pathway.


ensembl_gene_id: RGE_40550
symbol: pqqE
gene_biotype: protein_coding
description:
  Coenzyme PQQ synthesis protein E PqqE; Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).


ensembl_gene_id: RGE_40740
symbol: ureE
gene_biotype: protein_coding
description:
  Urease accessory protein UreE; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family.


ensembl_gene_id: RGE_40750
symbol: ureF
gene_biotype: protein_coding
description:
  Urease accessory protein UreF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.


ensembl_gene_id: RGE_40760
symbol: ureG
gene_biotype: protein_coding
description:
  Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.


ensembl_gene_id: RGE_40800
symbol: corA
gene_biotype: protein_coding
description:
  Magnesium and cobalt transport protein CorA; Mediates influx of magnesium ions. Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.


ensembl_gene_id: RGE_40860
symbol: psd
gene_biotype: protein_coding
description:
  Phosphatidylserine decarboxylase proenzyme Psd; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).


ensembl_gene_id: RGE_40900
symbol: rluC
gene_biotype: protein_coding
description:
  Ribosomal large subunit pseudouridine synthase C RluC; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.


ensembl_gene_id: RGE_40920
symbol: rne
gene_biotype: protein_coding
description:
  Ribonuclease E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily.


ensembl_gene_id: RGE_40940
symbol: nagZ
gene_biotype: protein_coding
description:
  beta-N-acetylhexosaminidase NagZ; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.


ensembl_gene_id: RGE_40950
symbol: acpS
gene_biotype: protein_coding
description:
  Holo-[acyl-carrier-protein] synthase AcpS; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.


ensembl_gene_id: RGE_40960
symbol: pdxJ
gene_biotype: protein_coding
description:
  Pyridoxine 5'-phosphate synthase PdxJ; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.


ensembl_gene_id: RGE_40980
symbol: era
gene_biotype: protein_coding
description:
  GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.


ensembl_gene_id: RGE_40990
symbol: rnc
gene_biotype: protein_coding
description:
  Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.


ensembl_gene_id: RGE_41020
symbol: lepA
gene_biotype: protein_coding
description:
  Elongation factor 4; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.


ensembl_gene_id: RGE_41090
symbol: fabF
gene_biotype: protein_coding
description:
  3-oxoacyl-[acyl-carrier-protein] synthase II, FabF; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.


ensembl_gene_id: RGE_41110
symbol: fabG
gene_biotype: protein_coding
description:
  3-oxoacyl-[acyl-carrier-protein] reductase, FabG; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: RGE_41130
symbol: fabH
gene_biotype: protein_coding
description:
  3-oxoacyl-[acyl-carrier-protein] synthase 3, FabH; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.


ensembl_gene_id: RGE_41140
symbol: plsX
gene_biotype: protein_coding
description:
  Fatty acid/phospholipid synthesis protein PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.


ensembl_gene_id: RGE_41170
symbol: RGE_41170
gene_biotype: protein_coding
description:
  Hypothetical protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes 7- methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids; Belongs to the Maf family. YceF subfamily.


ensembl_gene_id: RGE_41260
symbol: gmd
gene_biotype: protein_coding
description:
  GDP-mannose 4,6-dehydratase Gmd; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose.


ensembl_gene_id: RGE_41410
symbol: rmlC
gene_biotype: protein_coding
description:
  dTDP-4-keto-6-deoxyglucose-3,5-epimerase RmlC; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.


ensembl_gene_id: RGE_41420
symbol: rmlA
gene_biotype: protein_coding
description:
  Glucose-1-phosphate thymidylyltransferase RmlA; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.


ensembl_gene_id: RGE_41430
symbol: rmlD
gene_biotype: protein_coding
description:
  dTDP-4-dehydrorhamnose reductase RmlD; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family.


ensembl_gene_id: RGE_41440
symbol: rlmB
gene_biotype: protein_coding
description:
  dTDP-glucose 4,6-dehydratase RlmB; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.


ensembl_gene_id: RGE_41580
symbol: lysS
gene_biotype: protein_coding
description:
  lysyl-tRNA synthetase LysS; Protein synonym:lysine--tRNA ligase; Belongs to the class-II aminoacyl-tRNA synthetase family.


ensembl_gene_id: RGE_41610
symbol: fcl
gene_biotype: protein_coding
description:
  GDP-L-fucose synthase Fcl; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.


ensembl_gene_id: RGE_41660
symbol: dsbC
gene_biotype: protein_coding
description:
  Putative thiol:disulfide interchange protein DsbC; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily.


ensembl_gene_id: RGE_41690
symbol: thiE
gene_biotype: protein_coding
description:
  Thiamine-phosphate pyrophosphorylase ThiE; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.


ensembl_gene_id: RGE_41700
symbol: thiM
gene_biotype: protein_coding
description:
  Hydroxyethylthiazole kinase ThiM; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family.


ensembl_gene_id: RGE_41720
symbol: ychF
gene_biotype: protein_coding
description:
  GTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.


ensembl_gene_id: RGE_41760
symbol: rpoH
gene_biotype: protein_coding
description:
  RNA polymerase, sigma 32 subunit, RpoH; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.


ensembl_gene_id: RGE_41780
symbol: ctaB
gene_biotype: protein_coding
description:
  Protoheme IX farnesyltransferase CtaB; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.


ensembl_gene_id: RGE_41810
symbol: surf1
gene_biotype: protein_coding
description:
  Cytochrome oxidase assembly protein, SurF1 related; SURF1 superfamily. Surf1/Shy1 has been implicated in the posttranslational steps of the biogenesis of the mitochondrially-encoded Cox1 subunit of cytochrome c oxidase (complex IV).


ensembl_gene_id: RGE_41860
symbol: ctaD
gene_biotype: protein_coding
description:
  Cytochrome c oxidase subunit 1 CtaD; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.


ensembl_gene_id: RGE_41870
symbol: ctaC
gene_biotype: protein_coding
description:
  Cytochrome c oxidase subunit 2 CtaC; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).


ensembl_gene_id: RGE_41900
symbol: trmL
gene_biotype: protein_coding
description:
  RNA methyltransferase, TrmH family, group 2; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.


ensembl_gene_id: RGE_41910
symbol: gpsA
gene_biotype: protein_coding
description:
  Glycerol-3-phosphate dehydrogenase (NAD(P)+) GpsA; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.


ensembl_gene_id: RGE_41920
symbol: secB
gene_biotype: protein_coding
description:
  Preprotein translocase SecB subunit; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.


ensembl_gene_id: RGE_41930
symbol: grxC
gene_biotype: protein_coding
description:
  Glutaredoxin-3 GrxC; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.


ensembl_gene_id: RGE_41950
symbol: gpmA
gene_biotype: protein_coding
description:
  2,3-bisphosphoglycerate-dependent phosphoglycerate mutase GpmA; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.


ensembl_gene_id: RGE_41960
symbol: RGE_41960
gene_biotype: protein_coding
description:
  Putative ribose-phosphate pyrophosphokinase; Protein synonym:phosphoribosyl pyrophosphate synthase; Belongs to the ribose-phosphate pyrophosphokinase family.


ensembl_gene_id: RGE_42000
symbol: pyrB
gene_biotype: protein_coding
description:
  Aspartate carbamoyltransferase PyrB; Protein synonym:aspartate transcarbamylase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.


ensembl_gene_id: RGE_42010
symbol: pyrR
gene_biotype: protein_coding
description:
  Pyrimidine operon regulatory protein/uracil phosphoribosyltransferase; Bifunctional protein; protein synonym:bifunctional protein PyrR.


ensembl_gene_id: RGE_42020
symbol: RGE_42020
gene_biotype: protein_coding
description:
  Putative Holliday junction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family.


ensembl_gene_id: RGE_42140
symbol: hemL-2
gene_biotype: protein_coding
description:
  Glutamate-1-semialdehyde 2,1-aminomutase HemL; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.


ensembl_gene_id: RGE_42160
symbol: mpl
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramate: L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily.


ensembl_gene_id: RGE_42210
symbol: aroE
gene_biotype: protein_coding
description:
  Shikimate dehydrogenase AroE; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).


ensembl_gene_id: RGE_42220
symbol: mtgA
gene_biotype: protein_coding
description:
  Monofunctional biosynthetic peptidoglycan transglycosylase MtgA; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family.


ensembl_gene_id: RGE_42250
symbol: accB
gene_biotype: protein_coding
description:
  Biotin carboxyl carrier protein of acetyl-CoA carboxylase AccB; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.


ensembl_gene_id: RGE_42260
symbol: accC
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase, biotin carboxylase AccC; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.


ensembl_gene_id: RGE_42270
symbol: prmA
gene_biotype: protein_coding
description:
  Ribosomal protein L11 methyltransferase PrmA; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family.


ensembl_gene_id: RGE_42310
symbol: nrdB
gene_biotype: protein_coding
description:
  Ribonucleoside-diphosphate reductase, beta subunit NrdB; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.


ensembl_gene_id: RGE_42320
symbol: nrdA
gene_biotype: protein_coding
description:
  Ribonucleoside-diphosphate reductase, alpha subunit NrdA; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.


ensembl_gene_id: RGE_42380
symbol: ffh
gene_biotype: protein_coding
description:
  Signal recognition particle subunit FFH/SRP54; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individua [...]


ensembl_gene_id: RGE_42390
symbol: ftsY
gene_biotype: protein_coding
description:
  Signal recognition particle receptor FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.


ensembl_gene_id: RGE_42410
symbol: miaB
gene_biotype: protein_coding
description:
  tRNA-i(6)A37 modification enzyme MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.


ensembl_gene_id: RGE_42430
symbol: hemA
gene_biotype: protein_coding
description:
  glutamyl-tRNA reductase HemA; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).


ensembl_gene_id: RGE_42440
symbol: prfA
gene_biotype: protein_coding
description:
  Peptide chain release factor RF-1 PrfA; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.


ensembl_gene_id: RGE_42450
symbol: hemK
gene_biotype: protein_coding
description:
  Protein methyltransferase HemK; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.


ensembl_gene_id: RGE_42470
symbol: grxD
gene_biotype: protein_coding
description:
  Glutaredoxin-4; Protein synonym:monothiol glutaredoxin; Belongs to the glutaredoxin family. Monothiol subfamily.


ensembl_gene_id: RGE_42480
symbol: ubiX
gene_biotype: protein_coding
description:
  3-octaprenyl-4-hydroxybenzoate carboxy-lyase UbiX; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family.


ensembl_gene_id: RGE_42500
symbol: proS
gene_biotype: protein_coding
description:
  prolyl-tRNA synthetase ProS; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involve [...]


ensembl_gene_id: RGE_42510
symbol: rppH
gene_biotype: protein_coding
description:
  RNA pyrophosphohydrolase RppH; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily.


ensembl_gene_id: RGE_42520
symbol: proB
gene_biotype: protein_coding
description:
  Glutamate 5-kinase ProB; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.


ensembl_gene_id: RGE_42530
symbol: obg
gene_biotype: protein_coding
description:
  GTP-binding protein Obg/CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.


ensembl_gene_id: RGE_42550
symbol: rplU
gene_biotype: protein_coding
description:
  50S ribosomal protein L21 RplU; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.


ensembl_gene_id: RGE_42630
symbol: pilD
gene_biotype: protein_coding
description:
  Type 4 prepilin-like proteins leader peptide-processing enzyme PilD; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.


ensembl_gene_id: RGE_42640
symbol: coaE
gene_biotype: protein_coding
description:
  dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.


ensembl_gene_id: RGE_42650
symbol: yacF
gene_biotype: protein_coding
description:
  Protein YacF; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.


ensembl_gene_id: RGE_42660
symbol: yacG
gene_biotype: protein_coding
description:
  Zinc-binding protein YacG; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C- terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.


ensembl_gene_id: RGE_42850
symbol: draG
gene_biotype: protein_coding
description:
  ADP-ribosyl-[dinitrogen reductase] glycohydrolase DraG; Protein synonym:ADP-ribosylglycohydrolase; protein synonym:dinitrogenase reductase-activating glycohydrolase.


ensembl_gene_id: RGE_42880
symbol: nifH-2
gene_biotype: protein_coding
description:
  Nitrogenase iron protein NifH; The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein; Belongs to the NifH/BchL/ChlL family.


ensembl_gene_id: RGE_42900
symbol: nifK-2
gene_biotype: protein_coding
description:
  Nitrogenase molybdenum-iron protein beta chain NifK; This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation; Belongs to the NifD/NifK/NifE/NifN family.


ensembl_gene_id: RGE_42960
symbol: nifN
gene_biotype: protein_coding
description:
  Nitrogenase molybdenum-iron cofactor biosynthesis protein NifN; Belongs to the NifD/NifK/NifE/NifN family.


ensembl_gene_id: RGE_43110
symbol: nifW
gene_biotype: protein_coding
description:
  Nitrogenase-stabilizing/protective protein NifW; May protect the nitrogenase Fe-Mo protein from oxidative damage; Belongs to the NifW family.


ensembl_gene_id: RGE_43140
symbol: fixC
gene_biotype: protein_coding
description:
  Putative electron transfer flavoprotein ubiquinone oxidoreductase (ETF-QO) subunit FixC; Part of an electron transfer system. Belongs to the ETF-QO/FixC family.


ensembl_gene_id: RGE_43150
symbol: fixX
gene_biotype: protein_coding
description:
  Electron transfer flavoprotein ubiquinone oxidoreductase (ETF-QO) subunit FixX; Could be a 3Fe-4S cluster-containing protein.


ensembl_gene_id: RGE_43180
symbol: groES
gene_biotype: protein_coding
description:
  Co-chaperonin GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.


ensembl_gene_id: RGE_43190
symbol: groEL
gene_biotype: protein_coding
description:
  60 kDa chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.


ensembl_gene_id: RGE_43210
symbol: engB
gene_biotype: protein_coding
description:
  Ribosome biogenesis GTP-binding protein EngB; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.


ensembl_gene_id: RGE_43230
symbol: msrP
gene_biotype: protein_coding
description:
  Oxidoreductase molybdopterin binding; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce b [...]


ensembl_gene_id: RGE_43240
symbol: msrQ
gene_biotype: protein_coding
description:
  Ferric reductase-like transmembrane component-like; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase cat [...]


ensembl_gene_id: RGE_43250
symbol: uvrA
gene_biotype: protein_coding
description:
  UvrABC system protein A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.


ensembl_gene_id: RGE_43470
symbol: trkH
gene_biotype: protein_coding
description:
  Trk system potassium uptake protein TrkH; Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA; Belongs to the TrkH potassium transport family.


ensembl_gene_id: RGE_43530
symbol: aceK
gene_biotype: protein_coding
description:
  Isocitrate dehydrogenase kinase/phosphatase AceK; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.


ensembl_gene_id: RGE_43540
symbol: RGE_43540
gene_biotype: protein_coding
description:
  Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family.


ensembl_gene_id: RGE_43680
symbol: lnt
gene_biotype: protein_coding
description:
  Apolipoprotein N-acyltransferase Lnt; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily.


ensembl_gene_id: RGE_43710
symbol: dksA
gene_biotype: protein_coding
description:
  Putative DnaK suppressor protein DksA; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.


ensembl_gene_id: RGE_43730
symbol: hslV
gene_biotype: protein_coding
description:
  ATP-dependent protease subunit HslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.


ensembl_gene_id: RGE_43740
symbol: hslU
gene_biotype: protein_coding
description:
  ATP-dependent hsl protease ATP-binding subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.


ensembl_gene_id: RGE_43750
symbol: coaX
gene_biotype: protein_coding
description:
  Type III pantothenate kinase CoaX; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.


ensembl_gene_id: RGE_43760
symbol: icmF-2
gene_biotype: protein_coding
description:
  methylmalonyl-CoA mutase, putative; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.


ensembl_gene_id: RGE_43800
symbol: amn
gene_biotype: protein_coding
description:
  AMP nucleosidase Amn; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.


ensembl_gene_id: RGE_44010
symbol: ptsI
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate-protein phosphotransferase PtsI; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).


ensembl_gene_id: RGE_44060
symbol: lipA-2
gene_biotype: protein_coding
description:
  Lipoyl synthase LipA; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.


ensembl_gene_id: RGE_44070
symbol: lipB
gene_biotype: protein_coding
description:
  Lipoyltransferase LipB; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.


ensembl_gene_id: RGE_44180
symbol: ybeY
gene_biotype: protein_coding
description:
  Putative rRNA maturation factor; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.


ensembl_gene_id: RGE_44220
symbol: rubA
gene_biotype: protein_coding
description:
  Holliday junction ATP-dependent DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.


ensembl_gene_id: RGE_44240
symbol: ruvB
gene_biotype: protein_coding
description:
  Holliday junction ATP-dependent DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.


ensembl_gene_id: RGE_44390
symbol: rdgC
gene_biotype: protein_coding
description:
  Recombination-associated exonuclease RdgC; May be involved in recombination. Belongs to the RdgC family.


ensembl_gene_id: RGE_44540
symbol: cobO
gene_biotype: protein_coding
description:
  Cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.


ensembl_gene_id: RGE_44680
symbol: proA
gene_biotype: protein_coding
description:
  Glutamate-5-semialdehyde dehydrogenase ProA; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.


ensembl_gene_id: RGE_44760
symbol: cbbG
gene_biotype: protein_coding
description:
  Glyceraldehyde-3-phosphate dehydrogenase CbbG; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.


ensembl_gene_id: RGE_44830
symbol: glnE
gene_biotype: protein_coding
description:
  Glutamine synthetase adenylyltransferase GlnE; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal trans [...]


ensembl_gene_id: RGE_44990
symbol: corA-2
gene_biotype: protein_coding
description:
  Magnesium/nickel/cobalt transporter CorA; Mediates influx of magnesium ions. Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.


ensembl_gene_id: RGE_45100
symbol: hprK
gene_biotype: protein_coding
description:
  HPr kinase/phosphorylase HprK; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).


ensembl_gene_id: RGE_45120
symbol: bamE
gene_biotype: protein_coding
description:
  SmpA/OmlA domain-containing protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: RGE_45130
symbol: dapB
gene_biotype: protein_coding
description:
  Dihydrodipicolinate reductase DapB; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.


ensembl_gene_id: RGE_45160
symbol: leuS
gene_biotype: protein_coding
description:
  leucyl-tRNA synthetase LeuS; Protein synonym:leucine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: RGE_45170
symbol: lptE
gene_biotype: protein_coding
description:
  Putative LPS-assembly lipoprotein LptE; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane; Belongs to the LptE lipoprotein family.


ensembl_gene_id: RGE_45210
symbol: pgpA
gene_biotype: protein_coding
description:
  Phosphatidylglycerophosphatase A PgpA; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).


ensembl_gene_id: RGE_45220
symbol: thiL
gene_biotype: protein_coding
description:
  Thiamine-monophosphate kinase ThiL; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.


ensembl_gene_id: RGE_45290
symbol: rsmA
gene_biotype: protein_coding
description:
  Ribosomal RNA small subunit methyltransferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.


ensembl_gene_id: RGE_45300
symbol: surA
gene_biotype: protein_coding
description:
  Chaperone/peptidyl-prolyl cis-trans isomerase SurA; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.


ensembl_gene_id: RGE_45310
symbol: ostA
gene_biotype: protein_coding
description:
  Organic solvent tolerance protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.


ensembl_gene_id: RGE_45330
symbol: RGE_45330
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; Phosphotransferase family protein; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: RGE_45380
symbol: metX
gene_biotype: protein_coding
description:
  Homoserine O-acetyltransferase MetX; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.


ensembl_gene_id: RGE_45570
symbol: cdd
gene_biotype: protein_coding
description:
  Cytidine deaminase Cdd; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.


ensembl_gene_id: RGE_45580
symbol: punA
gene_biotype: protein_coding
description:
  Purine nucleoside phosphorylase PunA; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.


ensembl_gene_id: RGE_45740
symbol: deoC
gene_biotype: protein_coding
description:
  Deoxyribose-phosphate aldolase DeoC; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate.


ensembl_gene_id: RGE_45760
symbol: deoA-2
gene_biotype: protein_coding
description:
  Thymidine phosphorylase DeoA; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.


ensembl_gene_id: RGE_45870
symbol: pyrF
gene_biotype: protein_coding
description:
  Orotidine 5'-phosphate decarboxylase PyrF; Belongs to the OMP decarboxylase family. Type 2 subfamily.


ensembl_gene_id: RGE_45930
symbol: glcB
gene_biotype: protein_coding
description:
  Malate synthase G GlcB; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.


ensembl_gene_id: RGE_46030
symbol: lptA
gene_biotype: protein_coding
description:
  Putative lipopolysaccharide transport protein A LptA; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane.


ensembl_gene_id: RGE_46090
symbol: rsmE
gene_biotype: protein_coding
description:
  Ribosomal RNA small subunit methyltransferase E RsmE; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.


ensembl_gene_id: RGE_46200
symbol: cysA
gene_biotype: protein_coding
description:
  Sulfate ABC transporter, ATPase subunit CysA; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system.


ensembl_gene_id: RGE_46220
symbol: cysT
gene_biotype: protein_coding
description:
  Sulfate ABC transporter, inner membrane subunit CysT; Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: RGE_46320
symbol: acrA
gene_biotype: protein_coding
description:
  Secretion protein HlyD family protein AcrA; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: RGE_46350
symbol: ssb
gene_biotype: protein_coding
description:
  Single-stranded DNA-binding protein Ssb; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.


ensembl_gene_id: RGE_46390
symbol: uvrA-2
gene_biotype: protein_coding
description:
  UvrABC system protein A UvrA; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.


ensembl_gene_id: RGE_46440
symbol: moaC
gene_biotype: protein_coding
description:
  Molybdopterin cofactor biosynthesis protein MoaC; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.


ensembl_gene_id: RGE_46600
symbol: recA
gene_biotype: protein_coding
description:
  Protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.


ensembl_gene_id: RGE_46630
symbol: rodA
gene_biotype: protein_coding
description:
  Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.


ensembl_gene_id: RGE_46640
symbol: mrdA
gene_biotype: protein_coding
description:
  Penicillin-binding protein 2 MrdA; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.


ensembl_gene_id: RGE_46680
symbol: gatC
gene_biotype: protein_coding
description:
  aspartyl-tRNA(Asn)/glutamyl-tRNA (Gln) amidotransferase subunit C; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family.


ensembl_gene_id: RGE_46690
symbol: gatA
gene_biotype: protein_coding
description:
  aspartyl-tRNA(Asn)/glutamyl-tRNA (Gln) amidotransferase subunit A GatA; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln).


ensembl_gene_id: RGE_46700
symbol: gatB
gene_biotype: protein_coding
description:
  Putative aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily.


ensembl_gene_id: RGE_46720
symbol: pyrE
gene_biotype: protein_coding
description:
  Orotate phosphoribosyltransferase PyrE; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).


ensembl_gene_id: RGE_46850
symbol: mnmA
gene_biotype: protein_coding
description:
  tRNA-specific 2-thiouridylase MnmA; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.


ensembl_gene_id: RGE_46990
symbol: RGE_46990
gene_biotype: protein_coding
description:
  Sodium/hydrogen exchanger family protein; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.


ensembl_gene_id: RGE_47000
symbol: apt
gene_biotype: protein_coding
description:
  Adenine phosphoribosyltransferase Apt; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.


ensembl_gene_id: RGE_47020
symbol: trmE
gene_biotype: protein_coding
description:
  tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.


ensembl_gene_id: RGE_47030
symbol: yidC
gene_biotype: protein_coding
description:
  Protein translocase subunit YidC; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.


ensembl_gene_id: RGE_47040
symbol: RGE_47040
gene_biotype: protein_coding
description:
  Hypothetical protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family.


ensembl_gene_id: RGE_47050
symbol: RGE_47050
gene_biotype: protein_coding
description:
  Ribosomal protein S5 domain protein; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.


