# geneInfo

ensembl_gene_id: PB1_00080
symbol: selA
gene_biotype: protein_coding
description:
  Selenocysteine synthase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.


ensembl_gene_id: PB1_00085
symbol: PB1_00085
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0071 Molecular chaperone (small heat shock protein); Belongs to the small heat shock protein (HSP20) family.


ensembl_gene_id: PB1_00105
symbol: PB1_00105
gene_biotype: protein_coding
description:
  2-amino-3-ketobutyrate coenzyme A ligase; COG0156 7-keto-8-aminopelargonate synthetase and related enzymes.


ensembl_gene_id: PB1_00195
symbol: PB1_00195
gene_biotype: protein_coding
description:
  Maturation of the outermost layer of the spore; COG0463 Glycosyltransferases involved in cell wall biogenesis.


ensembl_gene_id: PB1_00285
symbol: PB1_00285
gene_biotype: protein_coding
description:
  Spore coat polysaccharide biosynthesis protein SpsL; COG1898 dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes.


ensembl_gene_id: PB1_00290
symbol: PB1_00290
gene_biotype: protein_coding
description:
  Spore coat polysaccharide synthesis (dTDP-4-dehydrorhamnose reductase); Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.


ensembl_gene_id: PB1_00295
symbol: PB1_00295
gene_biotype: protein_coding
description:
  Spore coat polysaccharide synthesis (dTDP glucose 4, 6-dehydratase); COG1088 dTDP-D-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.


ensembl_gene_id: PB1_00350
symbol: gmd
gene_biotype: protein_coding
description:
  GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose.


ensembl_gene_id: PB1_00405
symbol: PB1_00405
gene_biotype: protein_coding
description:
  Aminotransferase; COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: PB1_00410
symbol: PB1_00410
gene_biotype: protein_coding
description:
  Alcohol dehydrogenase GroES domain protein; COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases.


ensembl_gene_id: PB1_00420
symbol: PB1_00420
gene_biotype: protein_coding
description:
  Zinc-containing alcohol dehydrogenase; COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases.


ensembl_gene_id: PB1_00425
symbol: PB1_00425
gene_biotype: protein_coding
description:
  NADH:flavin oxidoreductase/NADH oxidase; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family.


ensembl_gene_id: PB1_00440
symbol: PB1_00440
gene_biotype: protein_coding
description:
  Quinone oxidoreductase, YhdH/YhfP family protein; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases.


ensembl_gene_id: PB1_00475
symbol: zwf2
gene_biotype: protein_coding
description:
  Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.


ensembl_gene_id: PB1_00485
symbol: phi
gene_biotype: protein_coding
description:
  6-phospho 3-hexuloisomerase; COG0794 Predicted sugar phosphate isomerase involved in capsule formation.


ensembl_gene_id: PB1_00490
symbol: PB1_00490
gene_biotype: protein_coding
description:
  Bacterial luciferase family protein; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: PB1_00525
symbol: sbcD
gene_biotype: protein_coding
description:
  Nuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.


ensembl_gene_id: PB1_00570
symbol: PB1_00570
gene_biotype: protein_coding
description:
  ABC transporter related protein; COG1132 ABC-type multidrug transport system, ATPase and permease components.


ensembl_gene_id: PB1_00595
symbol: tkt2
gene_biotype: protein_coding
description:
  Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.


ensembl_gene_id: PB1_00615
symbol: lexA
gene_biotype: protein_coding
description:
  LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.


ensembl_gene_id: PB1_00630
symbol: glnR
gene_biotype: protein_coding
description:
  Transcriptional repressor of the glutamine synthetase; COG0789 Predicted transcriptional regulators.


ensembl_gene_id: PB1_00635
symbol: PB1_00635
gene_biotype: protein_coding
description:
  Aluminum resistance protein; COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance.


ensembl_gene_id: PB1_00640
symbol: hflX
gene_biotype: protein_coding
description:
  GTP-binding proten HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.


ensembl_gene_id: PB1_00650
symbol: hfq
gene_biotype: protein_coding
description:
  RNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.


ensembl_gene_id: PB1_00655
symbol: miaA
gene_biotype: protein_coding
description:
  tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.


ensembl_gene_id: PB1_00665
symbol: mutL
gene_biotype: protein_coding
description:
  DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.


ensembl_gene_id: PB1_00670
symbol: mutS
gene_biotype: protein_coding
description:
  DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.


ensembl_gene_id: PB1_00690
symbol: miaB
gene_biotype: protein_coding
description:
  (dimethylallyl)adenosine tRNA methylthiotransferase; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.


ensembl_gene_id: PB1_00695
symbol: korB
gene_biotype: protein_coding
description:
  2-oxoglutarate synthase subunit beta; COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit.


ensembl_gene_id: PB1_00700
symbol: korA
gene_biotype: protein_coding
description:
  2-oxoglutarate synthase subunit alpha; COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit.


ensembl_gene_id: PB1_00720
symbol: recA
gene_biotype: protein_coding
description:
  Recombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.


ensembl_gene_id: PB1_00725
symbol: cinA
gene_biotype: protein_coding
description:
  Competence damage-inducible protein A; COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; Belongs to the CinA family.


ensembl_gene_id: PB1_00730
symbol: PB1_00730
gene_biotype: protein_coding
description:
  CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; COG0558 Phosphatidylglycerophosphate synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: PB1_00735
symbol: PB1_00735
gene_biotype: protein_coding
description:
  Transcriptional regulator, XRE family protein; COG1426 Uncharacterized protein conserved in bacteria.


ensembl_gene_id: PB1_00750
symbol: fabG1
gene_biotype: protein_coding
description:
  3-oxoacyl-[acyl-carrier-protein] reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: PB1_00785
symbol: PB1_00785
gene_biotype: protein_coding
description:
  Inner-membrane translocator; COG1079 Uncharacterized ABC-type transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: PB1_00790
symbol: PB1_00790
gene_biotype: protein_coding
description:
  ABC transporter permease; COG4603 ABC-type uncharacterized transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: PB1_00800
symbol: PB1_00800
gene_biotype: protein_coding
description:
  Basic membrane lipoprotein; COG1744 Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein.


ensembl_gene_id: PB1_00810
symbol: PB1_00810
gene_biotype: protein_coding
description:
  COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins; Belongs to the FtsK/SpoIIIE/SftA family.


ensembl_gene_id: PB1_00825
symbol: rnj
gene_biotype: protein_coding
description:
  mRNA degradation ribonucleases J1/J2; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay; Belongs to the metallo-beta-lactamase superfamily. RNA- metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.


ensembl_gene_id: PB1_00830
symbol: dapA
gene_biotype: protein_coding
description:
  Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).


ensembl_gene_id: PB1_00840
symbol: asd
gene_biotype: protein_coding
description:
  Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.


ensembl_gene_id: PB1_00845
symbol: dpaB
gene_biotype: protein_coding
description:
  Dipicolinate synthase subunit B; Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA).


ensembl_gene_id: PB1_00865
symbol: PB1_00865
gene_biotype: protein_coding
description:
  Sporulation protein, polysaccharide deacetylase family; COG0726 Predicted xylanase/chitin deacetylase.


ensembl_gene_id: PB1_00870
symbol: pnp
gene_biotype: protein_coding
description:
  Polynucleotide phosphorylase/polyadenylase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.


ensembl_gene_id: PB1_00875
symbol: rpsO
gene_biotype: protein_coding
description:
  30S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.


ensembl_gene_id: PB1_00885
symbol: truB
gene_biotype: protein_coding
description:
  tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.


ensembl_gene_id: PB1_00890
symbol: rbfA
gene_biotype: protein_coding
description:
  Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.


ensembl_gene_id: PB1_00900
symbol: infB
gene_biotype: protein_coding
description:
  Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.


ensembl_gene_id: PB1_00910
symbol: PB1_00910
gene_biotype: protein_coding
description:
  Hypothetical protein; COG2740 Predicted nucleic-acid-binding protein implicated in transcription termination.


ensembl_gene_id: PB1_00915
symbol: nusA
gene_biotype: protein_coding
description:
  Transcription elongation factor NusA; Participates in both transcription termination and antitermination.


ensembl_gene_id: PB1_00920
symbol: rimP
gene_biotype: protein_coding
description:
  Ribosome maturation protein RimP; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.


ensembl_gene_id: PB1_00925
symbol: polC
gene_biotype: protein_coding
description:
  DNA polymerase III PolC; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.


ensembl_gene_id: PB1_00930
symbol: proS
gene_biotype: protein_coding
description:
  prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...]


ensembl_gene_id: PB1_00940
symbol: dxr
gene_biotype: protein_coding
description:
  1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family.


ensembl_gene_id: PB1_00950
symbol: uppS
gene_biotype: protein_coding
description:
  Undecaprenyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.


ensembl_gene_id: PB1_00955
symbol: frr
gene_biotype: protein_coding
description:
  Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.


ensembl_gene_id: PB1_00965
symbol: tsf
gene_biotype: protein_coding
description:
  Elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.


ensembl_gene_id: PB1_00980
symbol: PB1_00980
gene_biotype: protein_coding
description:
  COG1191 DNA-directed RNA polymerase specialized sigma subunit; Belongs to the sigma-70 factor family.


ensembl_gene_id: PB1_00985
symbol: cheD
gene_biotype: protein_coding
description:
  CheD; Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the cheA kinase.


ensembl_gene_id: PB1_01005
symbol: cheB
gene_biotype: protein_coding
description:
  Chemotaxis-specific methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.


ensembl_gene_id: PB1_01020
symbol: flhA
gene_biotype: protein_coding
description:
  Flagellar biosynthesis protein FlhA; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.


ensembl_gene_id: PB1_01025
symbol: flhB
gene_biotype: protein_coding
description:
  Flagellar biosynthesis protein FlhB; Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the type III secretion exporter family.


ensembl_gene_id: PB1_01030
symbol: fliR
gene_biotype: protein_coding
description:
  Flagellar biosynthesis protein FliR; Role in flagellar biosynthesis. Belongs to the FliR/MopE/SpaR family.


ensembl_gene_id: PB1_01035
symbol: fliQ
gene_biotype: protein_coding
description:
  Flagellar biosynthesis protein FliQ; Role in flagellar biosynthesis. Belongs to the FliQ/MopD/SpaQ family.


ensembl_gene_id: PB1_01040
symbol: fliP
gene_biotype: protein_coding
description:
  Flagellar biosynthesis protein FliP; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family.


ensembl_gene_id: PB1_01055
symbol: PB1_01055
gene_biotype: protein_coding
description:
  Flagellar motor switch protein; FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliN/MopA/SpaO family.


ensembl_gene_id: PB1_01060
symbol: fliM
gene_biotype: protein_coding
description:
  Flagellar motor switch protein FliM; One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation; Belongs to the FliM family.


ensembl_gene_id: PB1_01065
symbol: fliL
gene_biotype: protein_coding
description:
  Flagellar basal body-associated protein FliL; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.


ensembl_gene_id: PB1_01110
symbol: fliG
gene_biotype: protein_coding
description:
  Flagellar motor switch protein G; One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation; Belongs to the FliG family.


ensembl_gene_id: PB1_01115
symbol: fliF
gene_biotype: protein_coding
description:
  Flagellar MS-ring protein; The M ring may be actively involved in energy transduction. Belongs to the FliF family.


ensembl_gene_id: PB1_01130
symbol: flgB
gene_biotype: protein_coding
description:
  Flagellar basal body rod protein FlgB; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.


ensembl_gene_id: PB1_01135
symbol: codY
gene_biotype: protein_coding
description:
  Transcriptional repressor CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; Belongs to the CodY family.


ensembl_gene_id: PB1_01140
symbol: hslU
gene_biotype: protein_coding
description:
  ATP-dependent protease ATP-binding subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.


ensembl_gene_id: PB1_01145
symbol: hslV
gene_biotype: protein_coding
description:
  ATP-dependent protease subunit HslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.


ensembl_gene_id: PB1_01150
symbol: xerC
gene_biotype: protein_coding
description:
  Site-specific tyrosine recombinase XerC; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.


ensembl_gene_id: PB1_01155
symbol: trmFO
gene_biotype: protein_coding
description:
  tRNA (uracil-5-)-methyltransferase Gid; Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs; Belongs to the MnmG family. TrmFO subfamily.


ensembl_gene_id: PB1_01160
symbol: topA
gene_biotype: protein_coding
description:
  DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]


ensembl_gene_id: PB1_01165
symbol: PB1_01165
gene_biotype: protein_coding
description:
  DNA protecting protein DprA; COG0758 Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake.


ensembl_gene_id: PB1_01170
symbol: sucD
gene_biotype: protein_coding
description:
  succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.


ensembl_gene_id: PB1_01175
symbol: sucC
gene_biotype: protein_coding
description:
  succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.


ensembl_gene_id: PB1_01180
symbol: PB1_01180
gene_biotype: protein_coding
description:
  Flagellar biosynthesis protein; COG2257 Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB.


ensembl_gene_id: PB1_01195
symbol: rbgA
gene_biotype: protein_coding
description:
  GTPase YlqF; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.


ensembl_gene_id: PB1_01205
symbol: rplS
gene_biotype: protein_coding
description:
  Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.


ensembl_gene_id: PB1_01210
symbol: trmD
gene_biotype: protein_coding
description:
  tRNA (guanine-N(1)-)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.


ensembl_gene_id: PB1_01215
symbol: rimM
gene_biotype: protein_coding
description:
  16S rRNA-processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family.


ensembl_gene_id: PB1_01235
symbol: ffh
gene_biotype: protein_coding
description:
  Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.


ensembl_gene_id: PB1_01240
symbol: PB1_01240
gene_biotype: protein_coding
description:
  Hypothetical protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.


ensembl_gene_id: PB1_01245
symbol: ftsY
gene_biotype: protein_coding
description:
  Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).


ensembl_gene_id: PB1_01250
symbol: smc
gene_biotype: protein_coding
description:
  Hypothetical protein; Required for chromosome condensation and partitioning. Belongs to the SMC family.


ensembl_gene_id: PB1_01255
symbol: rnc
gene_biotype: protein_coding
description:
  Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.


ensembl_gene_id: PB1_01265
symbol: fabG2
gene_biotype: protein_coding
description:
  3-oxoacyl-[acyl-carrier-protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: PB1_01275
symbol: plsX
gene_biotype: protein_coding
description:
  Putative phosphate acyltransferase; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.


ensembl_gene_id: PB1_01280
symbol: fapR
gene_biotype: protein_coding
description:
  Fatty acid biosynthesis transcriptional regulator; Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism.


ensembl_gene_id: PB1_01285
symbol: recG
gene_biotype: protein_coding
description:
  ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily.


ensembl_gene_id: PB1_01290
symbol: PB1_01290
gene_biotype: protein_coding
description:
  L-serine dehydratase, iron-sulfur-dependent, alpha subunit; COG1760 L-serine deaminase; Belongs to the iron-sulfur dependent L-serine dehydratase family.


ensembl_gene_id: PB1_01295
symbol: PB1_01295
gene_biotype: protein_coding
description:
  L-serine dehydratase, iron-sulfur-dependent, beta subunit; COG1760 L-serine deaminase; Belongs to the iron-sulfur dependent L-serine dehydratase family.


ensembl_gene_id: PB1_01325
symbol: rsgA
gene_biotype: protein_coding
description:
  GTPase RsgA; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.


ensembl_gene_id: PB1_01340
symbol: rlmN
gene_biotype: protein_coding
description:
  Ribosomal RNA large subunit methyltransferase N; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family.


ensembl_gene_id: PB1_01345
symbol: PB1_01345
gene_biotype: protein_coding
description:
  16S rRNA methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.


ensembl_gene_id: PB1_01350
symbol: fmt
gene_biotype: protein_coding
description:
  methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.


ensembl_gene_id: PB1_01355
symbol: def-2
gene_biotype: protein_coding
description:
  Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.


ensembl_gene_id: PB1_01360
symbol: priA
gene_biotype: protein_coding
description:
  Primosome assembly protein PriA; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.


ensembl_gene_id: PB1_01365
symbol: PB1_01365
gene_biotype: protein_coding
description:
  Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.


ensembl_gene_id: PB1_01370
symbol: rpoZ
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.


ensembl_gene_id: PB1_01400
symbol: pyrE
gene_biotype: protein_coding
description:
  Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).


ensembl_gene_id: PB1_01405
symbol: pyrF
gene_biotype: protein_coding
description:
  Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.


ensembl_gene_id: PB1_01415
symbol: pyrK
gene_biotype: protein_coding
description:
  Dihydroorotate dehydrogenase electron transfer subunit; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).


ensembl_gene_id: PB1_01430
symbol: pyrC
gene_biotype: protein_coding
description:
  Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.


ensembl_gene_id: PB1_01435
symbol: pyrB
gene_biotype: protein_coding
description:
  COG0540 Aspartate carbamoyltransferase, catalytic chain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.


ensembl_gene_id: PB1_01445
symbol: pyrR
gene_biotype: protein_coding
description:
  Bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant; Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.


ensembl_gene_id: PB1_01450
symbol: PB1_01450
gene_biotype: protein_coding
description:
  Pseudouridylate synthase, 23S RNA-specific; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.


ensembl_gene_id: PB1_01455
symbol: lspA
gene_biotype: protein_coding
description:
  Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.


ensembl_gene_id: PB1_01465
symbol: ileS
gene_biotype: protein_coding
description:
  isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.


ensembl_gene_id: PB1_01485
symbol: sepF
gene_biotype: protein_coding
description:
  Cell division machinery factor; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.


ensembl_gene_id: PB1_01490
symbol: PB1_01490
gene_biotype: protein_coding
description:
  Alanine racemase domain protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.


ensembl_gene_id: PB1_01510
symbol: PB1_01510
gene_biotype: protein_coding
description:
  Sporulation sigma factor SigG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.


ensembl_gene_id: PB1_01515
symbol: PB1_01515
gene_biotype: protein_coding
description:
  Sporulation sigma factor SigE; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.


ensembl_gene_id: PB1_01530
symbol: ftsZ
gene_biotype: protein_coding
description:
  Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.


ensembl_gene_id: PB1_01535
symbol: ftsA
gene_biotype: protein_coding
description:
  Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.


ensembl_gene_id: PB1_01570
symbol: murG
gene_biotype: protein_coding
description:
  Undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.


ensembl_gene_id: PB1_01580
symbol: murD
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.


ensembl_gene_id: PB1_01585
symbol: mraY
gene_biotype: protein_coding
description:
  phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.


ensembl_gene_id: PB1_01595
symbol: murE
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.


ensembl_gene_id: PB1_01615
symbol: rsmH
gene_biotype: protein_coding
description:
  S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.


ensembl_gene_id: PB1_01620
symbol: mraZ
gene_biotype: protein_coding
description:
  Cell division protein MraZ; COG2001 Uncharacterized protein conserved in bacteria; Belongs to the MraZ family.


ensembl_gene_id: PB1_01630
symbol: bshC
gene_biotype: protein_coding
description:
  Hypothetical protein; Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH.


ensembl_gene_id: PB1_01640
symbol: PB1_01640
gene_biotype: protein_coding
description:
  2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.


ensembl_gene_id: PB1_01685
symbol: tmcAL
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac- AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.


ensembl_gene_id: PB1_01705
symbol: coaD
gene_biotype: protein_coding
description:
  Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.


ensembl_gene_id: PB1_01735
symbol: PB1_01735
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain.


ensembl_gene_id: PB1_01760
symbol: PB1_01760
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit.


ensembl_gene_id: PB1_01790
symbol: PB1_01790
gene_biotype: protein_coding
description:
  Cytochrome c oxidase, subunit I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.


ensembl_gene_id: PB1_01795
symbol: PB1_01795
gene_biotype: protein_coding
description:
  Cytochrome c oxidase subunit 2; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).


ensembl_gene_id: PB1_01800
symbol: ctaB
gene_biotype: protein_coding
description:
  Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group; Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.


ensembl_gene_id: PB1_01805
symbol: ctaA
gene_biotype: protein_coding
description:
  Heme A synthase (monooxygenase); Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group; Belongs to the COX15/CtaA family. Type 1 subfamily.


ensembl_gene_id: PB1_01810
symbol: pyc
gene_biotype: protein_coding
description:
  Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.


ensembl_gene_id: PB1_01830
symbol: PB1_01830
gene_biotype: protein_coding
description:
  PhoH family protein; COG1875 Predicted ATPase related to phosphate starvation-inducible protein PhoH.


ensembl_gene_id: PB1_01870
symbol: PB1_01870
gene_biotype: protein_coding
description:
  COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family.


ensembl_gene_id: PB1_01940
symbol: pdhD
gene_biotype: protein_coding
description:
  Dihydrolipoyl dehydrogenase (E3 component); COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes.


ensembl_gene_id: PB1_01945
symbol: pdhC
gene_biotype: protein_coding
description:
  Dihydrolipoyllysine-residue acetyltransferase (E2 component); COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes.


ensembl_gene_id: PB1_01950
symbol: pdhB
gene_biotype: protein_coding
description:
  COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit.


ensembl_gene_id: PB1_01955
symbol: pdhA
gene_biotype: protein_coding
description:
  Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).


ensembl_gene_id: PB1_01970
symbol: PB1_01970
gene_biotype: protein_coding
description:
  Hypothetical protein; COG5503 Uncharacterized conserved small protein; Belongs to the UPF0356 family.


ensembl_gene_id: PB1_01975
symbol: rnj-2
gene_biotype: protein_coding
description:
  Ribonuclease J1; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay; Belongs to the metallo-beta-lactamase superfamily. RNA- metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.


ensembl_gene_id: PB1_01995
symbol: dapL
gene_biotype: protein_coding
description:
  N-acetyldiaminopimelate deacetylase; Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate.


ensembl_gene_id: PB1_02000
symbol: dapH
gene_biotype: protein_coding
description:
  Tetrahydrodipicolinate N-acetyltransferase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.


ensembl_gene_id: PB1_02090
symbol: PB1_02090
gene_biotype: protein_coding
description:
  6-phosphogluconate dehydrogenase NAD-binding protein; COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases.


ensembl_gene_id: PB1_02100
symbol: PB1_02100
gene_biotype: protein_coding
description:
  Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: PB1_02105
symbol: PB1_02105
gene_biotype: protein_coding
description:
  PtsI; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).


ensembl_gene_id: PB1_02150
symbol: PB1_02150
gene_biotype: protein_coding
description:
  ATPase AAA-2 domain protein; COG0542 ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family.


ensembl_gene_id: PB1_02185
symbol: mtnD
gene_biotype: protein_coding
description:
  Acireductone dioxygenase; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.


ensembl_gene_id: PB1_02190
symbol: mtnB
gene_biotype: protein_coding
description:
  Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).


ensembl_gene_id: PB1_02195
symbol: mtnX
gene_biotype: protein_coding
description:
  2-hydroxy-3-keto-5-methylthiopentenyl-1- phosphate phosphatase; Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl-1- phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene).


ensembl_gene_id: PB1_02200
symbol: mtnW
gene_biotype: protein_coding
description:
  2,3-diketo-5-methylthiopentyl-1-phosphate enolase; Catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5-methylthiopentenyl-1- phosphate (HK-MTPenyl-1-P); Belongs to the RuBisCO large chain family. Type IV subfamily.


ensembl_gene_id: PB1_02215
symbol: mtnK
gene_biotype: protein_coding
description:
  Methylthioribose kinase; Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate.


ensembl_gene_id: PB1_02220
symbol: PB1_02220
gene_biotype: protein_coding
description:
  O6-alkylguanine DNA alkyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.


ensembl_gene_id: PB1_02275
symbol: sigI
gene_biotype: protein_coding
description:
  Putative RNA polymerase sigma factor SigI; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; Belongs to the sigma-70 factor family. SigI subfamily.


ensembl_gene_id: PB1_02295
symbol: PB1_02295
gene_biotype: protein_coding
description:
  COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs.


ensembl_gene_id: PB1_02300
symbol: prfC
gene_biotype: protein_coding
description:
  Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.


ensembl_gene_id: PB1_02320
symbol: tgl
gene_biotype: protein_coding
description:
  Transglutaminase; Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links. Belongs to the bacillus TGase family.


ensembl_gene_id: PB1_02390
symbol: PB1_02390
gene_biotype: protein_coding
description:
  Dihydroxyacetone kinase, phosphotransfer subunit; COG3412 Uncharacterized protein conserved in bacteria.


ensembl_gene_id: PB1_02405
symbol: glpK
gene_biotype: protein_coding
description:
  Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.


ensembl_gene_id: PB1_02435
symbol: bioC
gene_biotype: protein_coding
description:
  SAM-dependent methyltransferase; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.


ensembl_gene_id: PB1_02440
symbol: PB1_02440
gene_biotype: protein_coding
description:
  Biotin biosynthesis protein BioH; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: PB1_02445
symbol: PB1_02445
gene_biotype: protein_coding
description:
  8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.


ensembl_gene_id: PB1_02450
symbol: cysI
gene_biotype: protein_coding
description:
  Sulfite reductase subunit beta; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.


ensembl_gene_id: PB1_02455
symbol: PB1_02455
gene_biotype: protein_coding
description:
  Sulfite reductase flavoprotein alpha-subunit; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.


ensembl_gene_id: PB1_02470
symbol: PB1_02470
gene_biotype: protein_coding
description:
  Type I site-specific deoxyribonuclease, HsdR family, putative; COG0610 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases.


ensembl_gene_id: PB1_02480
symbol: PB1_02480
gene_biotype: protein_coding
description:
  Biosurfactants production protein; COG2091 Phosphopantetheinyl transferase; Belongs to the P-Pant transferase superfamily.


ensembl_gene_id: PB1_02485
symbol: PB1_02485
gene_biotype: protein_coding
description:
  Amino acid adenylation domain protein; COG1020 Non-ribosomal peptide synthetase modules and related proteins.


ensembl_gene_id: PB1_02505
symbol: PB1_02505
gene_biotype: protein_coding
description:
  Prophage LambdaCh01 DNA binding domain-containing protein; COG1910 Periplasmic molybdate-binding protein/domain.


ensembl_gene_id: PB1_02580
symbol: PB1_02580
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1875 Predicted ATPase related to phosphate starvation-inducible protein PhoH.


ensembl_gene_id: PB1_02620
symbol: PB1_02620
gene_biotype: protein_coding
description:
  DNA mismatch endonuclease, patch repair protein Vsr; May nick specific sequences that contain T:G mispairs resulting from m5C-deamination.


ensembl_gene_id: PB1_02630
symbol: PB1_02630
gene_biotype: protein_coding
description:
  Helicase domain protein; COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster.


ensembl_gene_id: PB1_02660
symbol: PB1_02660
gene_biotype: protein_coding
description:
  ATPase associated with various cellular activities AAA_5; COG1401 GTPase subunit of restriction endonuclease.


ensembl_gene_id: PB1_02705
symbol: PB1_02705
gene_biotype: protein_coding
description:
  Glutamine ABC transporter ATP-binding protein GlnQ; COG1126 ABC-type polar amino acid transport system, ATPase component.


ensembl_gene_id: PB1_02710
symbol: PB1_02710
gene_biotype: protein_coding
description:
  Glutamine ABC transporter; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; Belongs to the bacterial solute-binding protein 3 family.


ensembl_gene_id: PB1_02715
symbol: PB1_02715
gene_biotype: protein_coding
description:
  Glutamine ABC transporter membrane protein; COG0765 ABC-type amino acid transport system, permease component.


ensembl_gene_id: PB1_02720
symbol: PB1_02720
gene_biotype: protein_coding
description:
  Glutamine ABC transporter permease GlnP; COG0765 ABC-type amino acid transport system, permease component.


ensembl_gene_id: PB1_02725
symbol: PB1_02725
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1514 2'-5' RNA ligase; Belongs to the 2H phosphoesterase superfamily. YjcG family.


ensembl_gene_id: PB1_02730
symbol: PB1_02730
gene_biotype: protein_coding
description:
  GCN5-related N-acetyltransferase; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases.


ensembl_gene_id: PB1_02790
symbol: PB1_02790
gene_biotype: protein_coding
description:
  Pseudouridine synthase, RluA family protein; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.


ensembl_gene_id: PB1_02800
symbol: ppnK
gene_biotype: protein_coding
description:
  Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.


ensembl_gene_id: PB1_02820
symbol: PB1_02820
gene_biotype: protein_coding
description:
  COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains).


ensembl_gene_id: PB1_02830
symbol: PB1_02830
gene_biotype: protein_coding
description:
  Hypothetical protein; COG2761 Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis.


ensembl_gene_id: PB1_02855
symbol: cls
gene_biotype: protein_coding
description:
  Cardiolipin synthetase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.


ensembl_gene_id: PB1_02860
symbol: mecA
gene_biotype: protein_coding
description:
  Adaptor protein; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC.


ensembl_gene_id: PB1_02865
symbol: spxA
gene_biotype: protein_coding
description:
  Transcriptional regulator Spx; Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development- promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress. Belongs to the ArsC family. Spx subfamily.


ensembl_gene_id: PB1_02875
symbol: PB1_02875
gene_biotype: protein_coding
description:
  Oligopeptide/dipeptide ABC transporter, ATPase subunit; COG4608 ABC-type oligopeptide transport system, ATPase component; Belongs to the ABC transporter superfamily.


ensembl_gene_id: PB1_02880
symbol: PB1_02880
gene_biotype: protein_coding
description:
  Oligopeptide/dipeptide ABC transporter, ATPase subunit; COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component; Belongs to the ABC transporter superfamily.


ensembl_gene_id: PB1_02895
symbol: PB1_02895
gene_biotype: protein_coding
description:
  Extracellular solute-binding protein family 5; COG4166 ABC-type oligopeptide transport system, periplasmic component.


ensembl_gene_id: PB1_02900
symbol: trpS
gene_biotype: protein_coding
description:
  tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: PB1_02925
symbol: PB1_02925
gene_biotype: protein_coding
description:
  Oligopeptide ABC transporter ATP-binding protein; COG4608 ABC-type oligopeptide transport system, ATPase component; Belongs to the ABC transporter superfamily.


ensembl_gene_id: PB1_02930
symbol: PB1_02930
gene_biotype: protein_coding
description:
  Oligopeptide ABC transporter ATP-binding protein; COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component; Belongs to the ABC transporter superfamily.


ensembl_gene_id: PB1_02940
symbol: PB1_02940
gene_biotype: protein_coding
description:
  3-oxoacyl-(acyl carrier protein) synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.


ensembl_gene_id: PB1_02945
symbol: fabH
gene_biotype: protein_coding
description:
  3-oxoacyl-(acyl carrier protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.


ensembl_gene_id: PB1_02955
symbol: PB1_02955
gene_biotype: protein_coding
description:
  Transcriptional activator protein Med; COG1744 Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein.


ensembl_gene_id: PB1_02975
symbol: clpB
gene_biotype: protein_coding
description:
  ATPase; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.


ensembl_gene_id: PB1_02985
symbol: PB1_02985
gene_biotype: protein_coding
description:
  Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.


ensembl_gene_id: PB1_03000
symbol: argD
gene_biotype: protein_coding
description:
  COG4992 Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.


ensembl_gene_id: PB1_03005
symbol: argB
gene_biotype: protein_coding
description:
  Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.


ensembl_gene_id: PB1_03010
symbol: argJ
gene_biotype: protein_coding
description:
  Bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.


ensembl_gene_id: PB1_03015
symbol: argC
gene_biotype: protein_coding
description:
  N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.


ensembl_gene_id: PB1_03025
symbol: PB1_03025
gene_biotype: protein_coding
description:
  Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.


ensembl_gene_id: PB1_03030
symbol: moaA
gene_biotype: protein_coding
description:
  Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.


ensembl_gene_id: PB1_03035
symbol: PB1_03035
gene_biotype: protein_coding
description:
  N-6 adenine-specific DNA methylase YitW; COG2151 Predicted metal-sulfur cluster biosynthetic enzyme.


ensembl_gene_id: PB1_03090
symbol: PB1_03090
gene_biotype: protein_coding
description:
  Putative nucleotide-binding protein; COG1666 Uncharacterized protein conserved in bacteria; Belongs to the UPF0234 family.


ensembl_gene_id: PB1_03095
symbol: PB1_03095
gene_biotype: protein_coding
description:
  COG1501 Alpha-glucosidases, family 31 of glycosyl hydrolases; Belongs to the glycosyl hydrolase 31 family.


ensembl_gene_id: PB1_03135
symbol: PB1_03135
gene_biotype: protein_coding
description:
  Two component transcriptional regulator, LuxR family protein; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: PB1_03155
symbol: PB1_03155
gene_biotype: protein_coding
description:
  5-carboxymethyl-2-hydroxymuconate Delta-isomerase; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).


ensembl_gene_id: PB1_03165
symbol: PB1_03165
gene_biotype: protein_coding
description:
  Alcohol dehydrogenase, zinc-containing; COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases.


ensembl_gene_id: PB1_03210
symbol: addB
gene_biotype: protein_coding
description:
  ATP-dependent helicase/deoxyribonuclease subunit B; ATP-dependent DNA helicase; Belongs to the helicase family. AddB/RexB type 1 subfamily.


ensembl_gene_id: PB1_03275
symbol: PB1_03275
gene_biotype: protein_coding
description:
  ABC transporter related protein; COG1101 ABC-type uncharacterized transport system, ATPase component.


ensembl_gene_id: PB1_03280
symbol: PB1_03280
gene_biotype: protein_coding
description:
  Inner-membrane translocator; COG4120 ABC-type uncharacterized transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: PB1_03295
symbol: PB1_03295
gene_biotype: protein_coding
description:
  Enoyl-CoA hydratase/isomerase family protein; COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: PB1_03300
symbol: PB1_03300
gene_biotype: protein_coding
description:
  Metallo-beta-lactamase family protein; COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III.


ensembl_gene_id: PB1_03320
symbol: PB1_03320
gene_biotype: protein_coding
description:
  Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.


ensembl_gene_id: PB1_03325
symbol: hemH
gene_biotype: protein_coding
description:
  Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.


ensembl_gene_id: PB1_03330
symbol: hemE
gene_biotype: protein_coding
description:
  Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.


ensembl_gene_id: PB1_03345
symbol: PB1_03345
gene_biotype: protein_coding
description:
  Hypothetical protein; COG2329 Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides.


ensembl_gene_id: PB1_03415
symbol: PB1_03415
gene_biotype: protein_coding
description:
  ABC transporter, ATP-binding protein ecsa; COG1131 ABC-type multidrug transport system, ATPase component.


ensembl_gene_id: PB1_03420
symbol: PB1_03420
gene_biotype: protein_coding
description:
  Histidine triad (HIT) protein; COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases.


ensembl_gene_id: PB1_03425
symbol: serC
gene_biotype: protein_coding
description:
  3-phosphoserine/phosphohydroxythreonine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine.


ensembl_gene_id: PB1_03455
symbol: prsA
gene_biotype: protein_coding
description:
  Protein export protein prsA; Plays a major role in protein secretion by helping the post- translocational extracellular folding of several secreted proteins.


ensembl_gene_id: PB1_03490
symbol: PB1_03490
gene_biotype: protein_coding
description:
  ABC transporter related protein; COG4152 ABC-type uncharacterized transport system, ATPase component.


ensembl_gene_id: PB1_03545
symbol: PB1_03545
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase).


ensembl_gene_id: PB1_03560
symbol: PB1_03560
gene_biotype: protein_coding
description:
  ABC transporter related protein; COG3839 ABC-type sugar transport systems, ATPase components; Belongs to the ABC transporter superfamily.


ensembl_gene_id: PB1_03575
symbol: fumC
gene_biotype: protein_coding
description:
  Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.


ensembl_gene_id: PB1_03580
symbol: PB1_03580
gene_biotype: protein_coding
description:
  Isoaspartyl dipeptidase; Catalyzes the hydrolytic cleavage of a subset of L- isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation. Belongs to the peptidase M38 family.


ensembl_gene_id: PB1_03585
symbol: PB1_03585
gene_biotype: protein_coding
description:
  Penicillin-binding protein, peptidoglycan glycosyltransferase; COG0744 Membrane carboxypeptidase (penicillin-binding protein).


ensembl_gene_id: PB1_03590
symbol: PB1_03590
gene_biotype: protein_coding
description:
  Cation efflux system; COG0053 Predicted Co/Zn/Cd cation transporters; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.


ensembl_gene_id: PB1_03620
symbol: PB1_03620
gene_biotype: protein_coding
description:
  Sulfatase; COG1368 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily; Belongs to the LTA synthase family.


ensembl_gene_id: PB1_03655
symbol: PB1_03655
gene_biotype: protein_coding
description:
  Cysteine exporter protein CydC; COG4987 ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components.


ensembl_gene_id: PB1_03660
symbol: PB1_03660
gene_biotype: protein_coding
description:
  ABC transporter required for expression of cytochrome BD; COG4988 ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components.


ensembl_gene_id: PB1_03700
symbol: bdbC
gene_biotype: protein_coding
description:
  Putative disulfide oxidoreductase; Required for disulfide bond formation in some proteins. Belongs to the DsbB family. BdbC subfamily.


ensembl_gene_id: PB1_03715
symbol: PB1_03715
gene_biotype: protein_coding
description:
  Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.


ensembl_gene_id: PB1_03735
symbol: PB1_03735
gene_biotype: protein_coding
description:
  AcrB/AcrD/AcrF family transporter; COG0841 Cation/multidrug efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: PB1_03770
symbol: PB1_03770
gene_biotype: protein_coding
description:
  rRNA methylase; Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.


ensembl_gene_id: PB1_03870
symbol: PB1_03870
gene_biotype: protein_coding
description:
  Phosphate ABC transporter, inner membrane subunit PstA; COG0581 ABC-type phosphate transport system, permease component.


ensembl_gene_id: PB1_03875
symbol: PB1_03875
gene_biotype: protein_coding
description:
  Phosphate ABC transporter, inner membrane subunit PstC; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: PB1_03905
symbol: perR
gene_biotype: protein_coding
description:
  Peroxide regulon repressor perR, fur family protein; COG0735 Fe2+/Zn2+ uptake regulation proteins; Belongs to the Fur family.


ensembl_gene_id: PB1_03920
symbol: PB1_03920
gene_biotype: protein_coding
description:
  Putative ABC transporter, permease protein; COG3694 ABC-type uncharacterized transport system, permease component.


ensembl_gene_id: PB1_03925
symbol: PB1_03925
gene_biotype: protein_coding
description:
  Putative ABC transporter, permease protein; COG4587 ABC-type uncharacterized transport system, permease component.


ensembl_gene_id: PB1_03930
symbol: PB1_03930
gene_biotype: protein_coding
description:
  ABC transporter related protein; COG4586 ABC-type uncharacterized transport system, ATPase component.


ensembl_gene_id: PB1_03945
symbol: PB1_03945
gene_biotype: protein_coding
description:
  Putative multidrug export ABC transporter ATP-binding/permease protein; COG1132 ABC-type multidrug transport system, ATPase and permease components.


ensembl_gene_id: PB1_03950
symbol: PB1_03950
gene_biotype: protein_coding
description:
  COG3557 Uncharacterized domain/protein associated with RNAses G and E; Belongs to the UPF0374 family.


ensembl_gene_id: PB1_03965
symbol: PB1_03965
gene_biotype: protein_coding
description:
  Enoyl-(acyl carrier protein) reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: PB1_04015
symbol: PB1_04015
gene_biotype: protein_coding
description:
  NAD dependent epimerase/dehydratase family protein; COG1090 Predicted nucleoside-diphosphate sugar epimerase.


ensembl_gene_id: PB1_04110
symbol: PB1_04110
gene_biotype: protein_coding
description:
  Transcriptional regulator; COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases.


ensembl_gene_id: PB1_04185
symbol: PB1_04185
gene_biotype: protein_coding
description:
  Sigma-70 region 4 type 2; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog.


ensembl_gene_id: PB1_04220
symbol: PB1_04220
gene_biotype: protein_coding
description:
  Putative type I restriction enzyme specificity protein; COG0732 Restriction endonuclease S subunits.


ensembl_gene_id: PB1_04225
symbol: PB1_04225
gene_biotype: protein_coding
description:
  Type I site-specific deoxyribonuclease, HsdR family protein; Subunit R is required for both nuclease and ATPase activities, but not for modification.


ensembl_gene_id: PB1_04235
symbol: PB1_04235
gene_biotype: protein_coding
description:
  RNA methyltransferase, TrmA family protein; COG2265 SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.


ensembl_gene_id: PB1_04250
symbol: fumA
gene_biotype: protein_coding
description:
  Fumarate hydratase class I, aerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.


ensembl_gene_id: PB1_04265
symbol: PB1_04265
gene_biotype: protein_coding
description:
  Calcium/proton antiporter, CaCA family protein; Ca(+)/H(+) antiporter that extrudes calcium in exchange for external protons.


ensembl_gene_id: PB1_04310
symbol: map
gene_biotype: protein_coding
description:
  Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.


ensembl_gene_id: PB1_04370
symbol: queF
gene_biotype: protein_coding
description:
  7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.


ensembl_gene_id: PB1_04415
symbol: PB1_04415
gene_biotype: protein_coding
description:
  Ribonuclease activity regulator protein RraA; Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.


ensembl_gene_id: PB1_04435
symbol: PB1_04435
gene_biotype: protein_coding
description:
  ABC transporter-like protein; COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component.


ensembl_gene_id: PB1_04440
symbol: PB1_04440
gene_biotype: protein_coding
description:
  Binding-protein-dependent transporter inner membrane component; COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component.


ensembl_gene_id: PB1_04445
symbol: PB1_04445
gene_biotype: protein_coding
description:
  Aliphatic sulfonate family ABC transporter periplasmic ligand-binding protein; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components.


ensembl_gene_id: PB1_04475
symbol: thiE
gene_biotype: protein_coding
description:
  Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.


ensembl_gene_id: PB1_04485
symbol: thiM
gene_biotype: protein_coding
description:
  Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family.


ensembl_gene_id: PB1_04510
symbol: lytT
gene_biotype: protein_coding
description:
  LytTR family two component transcriptional regulator; COG3279 Response regulator of the LytR/AlgR family.


ensembl_gene_id: PB1_04535
symbol: PB1_04535
gene_biotype: protein_coding
description:
  Putative transcriptional regulator; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: PB1_04615
symbol: PB1_04615
gene_biotype: protein_coding
description:
  Glutamine ABC transporter periplasmic-binding component; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; Belongs to the bacterial solute-binding protein 3 family.


ensembl_gene_id: PB1_04635
symbol: PB1_04635
gene_biotype: protein_coding
description:
  Hypothetical protein; COG2905 Predicted signal-transduction protein containing cAMP-binding and CBS domains.


ensembl_gene_id: PB1_04655
symbol: PB1_04655
gene_biotype: protein_coding
description:
  D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: PB1_04665
symbol: PB1_04665
gene_biotype: protein_coding
description:
  Succinate-semialdehyde dehydrogenase (NADP+); COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: PB1_04670
symbol: PB1_04670
gene_biotype: protein_coding
description:
  ABC transporter related protein; COG1126 ABC-type polar amino acid transport system, ATPase component.


ensembl_gene_id: PB1_04675
symbol: PB1_04675
gene_biotype: protein_coding
description:
  Polar amino acid ABC transporter, inner membrane subunit; COG0765 ABC-type amino acid transport system, permease component.


ensembl_gene_id: PB1_04680
symbol: PB1_04680
gene_biotype: protein_coding
description:
  Extracellular solute-binding protein; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain.


ensembl_gene_id: PB1_04705
symbol: PB1_04705
gene_biotype: protein_coding
description:
  RNA-metabolising metallo-beta-lactamase; COG1236 Predicted exonuclease of the beta-lactamase fold involved in RNA processing.


ensembl_gene_id: PB1_04745
symbol: PB1_04745
gene_biotype: protein_coding
description:
  Branched-chain amino acid transport system II carrier protein; Component of the transport system for branched-chain amino acids.


ensembl_gene_id: PB1_04760
symbol: pxpA
gene_biotype: protein_coding
description:
  LamB/YcsF family protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.


ensembl_gene_id: PB1_04770
symbol: PB1_04770
gene_biotype: protein_coding
description:
  Iron-sulfur cluster repair di-iron protein; Di-iron-containing protein involved in the repair of iron- sulfur clusters; Belongs to the RIC family.


ensembl_gene_id: PB1_04855
symbol: PB1_04855
gene_biotype: protein_coding
description:
  uroporphyrin-III C-methyltransferase; COG0007 Uroporphyrinogen-III methylase; Belongs to the precorrin methyltransferase family.


ensembl_gene_id: PB1_04865
symbol: PB1_04865
gene_biotype: protein_coding
description:
  COG0155 Sulfite reductase, beta subunit (hemoprotein); Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.


ensembl_gene_id: PB1_04875
symbol: sat
gene_biotype: protein_coding
description:
  COG2046 ATP sulfurylase (sulfate adenylyltransferase); Belongs to the sulfate adenylyltransferase family.


ensembl_gene_id: PB1_04880
symbol: cysH
gene_biotype: protein_coding
description:
  Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.


ensembl_gene_id: PB1_04895
symbol: PB1_04895
gene_biotype: protein_coding
description:
  Glyoxalase/bleomycin resistance protein/dioxygenase; COG2764 Uncharacterized protein conserved in bacteria.


ensembl_gene_id: PB1_04910
symbol: PB1_04910
gene_biotype: protein_coding
description:
  Propanediol utilization phosphotransacylase; Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.


ensembl_gene_id: PB1_04930
symbol: PB1_04930
gene_biotype: protein_coding
description:
  Cys/Met metabolism pyridoxal-phosphate-dependent protein; COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases.


ensembl_gene_id: PB1_04945
symbol: PB1_04945
gene_biotype: protein_coding
description:
  Family 3 extracellular solute-binding protein; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components.


ensembl_gene_id: PB1_04960
symbol: PB1_04960
gene_biotype: protein_coding
description:
  ABC transporter related protein; COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component.


ensembl_gene_id: PB1_04970
symbol: PB1_04970
gene_biotype: protein_coding
description:
  Xenobiotic compound monooxygenase A subunit; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: PB1_04975
symbol: PB1_04975
gene_biotype: protein_coding
description:
  ABC transporter permease; COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component.


ensembl_gene_id: PB1_04980
symbol: PB1_04980
gene_biotype: protein_coding
description:
  ABC-type transporter, ATP-binding protein; COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component.


ensembl_gene_id: PB1_04995
symbol: PB1_04995
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family protein; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: PB1_05000
symbol: PB1_05000
gene_biotype: protein_coding
description:
  Luciferase family oxidoreductase, group 1; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: PB1_05015
symbol: PB1_05015
gene_biotype: protein_coding
description:
  Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: PB1_05040
symbol: PB1_05040
gene_biotype: protein_coding
description:
  Oligopeptide/dipeptide ABC transporter, ATPase subunit; COG4608 ABC-type oligopeptide transport system, ATPase component.


ensembl_gene_id: PB1_05050
symbol: PB1_05050
gene_biotype: protein_coding
description:
  Extracellular solute-binding protein family 5; COG0747 ABC-type dipeptide transport system, periplasmic component.


ensembl_gene_id: PB1_05055
symbol: PB1_05055
gene_biotype: protein_coding
description:
  Luciferase-like monooxygenase; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: PB1_05160
symbol: PB1_05160
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; Belongs to the arginase family.


ensembl_gene_id: PB1_05200
symbol: fosB
gene_biotype: protein_coding
description:
  Fosfomycin resistance protein FosB; Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor. Belongs to the fosfomycin resistance protein family. FosB subfamily.


ensembl_gene_id: PB1_05285
symbol: gltC
gene_biotype: protein_coding
description:
  Transcriptional activator of the glutamate synthase operon; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: PB1_05442
symbol: PB1_05442
gene_biotype: protein_coding
description:
  NLPA lipoprotein; COG1464 ABC-type metal ion transport system, periplasmic component/surface antigen; Belongs to the nlpA lipoprotein family.


ensembl_gene_id: PB1_05462
symbol: PB1_05462
gene_biotype: protein_coding
description:
  Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.


ensembl_gene_id: PB1_05467
symbol: PB1_05467
gene_biotype: protein_coding
description:
  Putative lipid kinase; COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase.


ensembl_gene_id: PB1_05472
symbol: uppP
gene_biotype: protein_coding
description:
  Undecaprenyl pyrophosphate phosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.


ensembl_gene_id: PB1_05487
symbol: PB1_05487
gene_biotype: protein_coding
description:
  COG0394 Protein-tyrosine-phosphatase; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.


ensembl_gene_id: PB1_05492
symbol: racA
gene_biotype: protein_coding
description:
  Polar chromosome segregation protein; Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure; Belongs to the RacA family.


ensembl_gene_id: PB1_05502
symbol: thiC
gene_biotype: protein_coding
description:
  Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.


ensembl_gene_id: PB1_05512
symbol: gatB
gene_biotype: protein_coding
description:
  aspartyl/glutamyl-tRNA amidotransferase subunit B; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily.


ensembl_gene_id: PB1_05517
symbol: gatA
gene_biotype: protein_coding
description:
  aspartyl/glutamyl-tRNA amidotransferase subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln).


ensembl_gene_id: PB1_05522
symbol: gatC
gene_biotype: protein_coding
description:
  aspartyl/glutamyl-tRNA amidotransferase subunit C; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family.


ensembl_gene_id: PB1_05542
symbol: rocA
gene_biotype: protein_coding
description:
  COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. RocA subfamily.


ensembl_gene_id: PB1_05552
symbol: ligA
gene_biotype: protein_coding
description:
  NAD-dependent DNA ligase LigA; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily.


ensembl_gene_id: PB1_05562
symbol: pcrB
gene_biotype: protein_coding
description:
  Geranylgeranylglyceryl phosphate synthase-like protein; Prenyltransferase that catalyzes in vivo the transfer of the heptaprenyl moiety of heptaprenyl pyrophosphate (HepPP; 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond- formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales.


ensembl_gene_id: PB1_05587
symbol: purH
gene_biotype: protein_coding
description:
  Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful).


ensembl_gene_id: PB1_05592
symbol: purN
gene_biotype: protein_coding
description:
  Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.


ensembl_gene_id: PB1_05602
symbol: purF
gene_biotype: protein_coding
description:
  Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.


ensembl_gene_id: PB1_05607
symbol: purL
gene_biotype: protein_coding
description:
  Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist  [...]


ensembl_gene_id: PB1_05612
symbol: purQ
gene_biotype: protein_coding
description:
  Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...]


ensembl_gene_id: PB1_05617
symbol: purS
gene_biotype: protein_coding
description:
  Phosphoribosylformylglycinamidine synthase subunit PurS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought  [...]


ensembl_gene_id: PB1_05622
symbol: purC
gene_biotype: protein_coding
description:
  COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family.


ensembl_gene_id: PB1_05632
symbol: purK
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazole carboxylase ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).


ensembl_gene_id: PB1_05637
symbol: purE
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazole carboxylase catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).


ensembl_gene_id: PB1_05647
symbol: PB1_05647
gene_biotype: protein_coding
description:
  PTS glucose-specific transporter subunit IICBA; COG1263 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific.


ensembl_gene_id: PB1_05667
symbol: PB1_05667
gene_biotype: protein_coding
description:
  Transglutaminase domain protein; COG1305 Transglutaminase-like enzymes, putative cysteine proteases.


ensembl_gene_id: PB1_05672
symbol: PB1_05672
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1721 Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain).


ensembl_gene_id: PB1_05702
symbol: PB1_05702
gene_biotype: protein_coding
description:
  Drug resistance transporter, EmrB/QacA subfamily protein; COG0477 Permeases of the major facilitator superfamily.


ensembl_gene_id: PB1_05777
symbol: PB1_05777
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: PB1_05802
symbol: PB1_05802
gene_biotype: protein_coding
description:
  RNA polymerase, sigma-24 subunit, ECF subfamily protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: PB1_05807
symbol: groEL
gene_biotype: protein_coding
description:
  Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.


ensembl_gene_id: PB1_05812
symbol: groES
gene_biotype: protein_coding
description:
  Co-chaperonin GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.


ensembl_gene_id: PB1_05827
symbol: rex
gene_biotype: protein_coding
description:
  Redox-sensing transcriptional repressor Rex; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.


ensembl_gene_id: PB1_05832
symbol: moaC
gene_biotype: protein_coding
description:
  Molybdenum cofactor biosynthesis protein MoaC; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.


ensembl_gene_id: PB1_05847
symbol: tsaD
gene_biotype: protein_coding
description:
  UGMP family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.


ensembl_gene_id: PB1_05852
symbol: PB1_05852
gene_biotype: protein_coding
description:
  Ribosomal-protein-alanine acetyltransferase; Acetylates the N-terminal alanine of ribosomal protein S18.


ensembl_gene_id: PB1_05857
symbol: PB1_05857
gene_biotype: protein_coding
description:
  Glycoprotease family protein; COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone.


ensembl_gene_id: PB1_05907
symbol: rsbW
gene_biotype: protein_coding
description:
  Serine-protein kinase RsbW; Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B).


ensembl_gene_id: PB1_05917
symbol: PB1_05917
gene_biotype: protein_coding
description:
  Transcriptional modulator of MazE/toxin, MazF; Toxic component of a type II toxin-antitoxin (TA) system.


ensembl_gene_id: PB1_05922
symbol: PB1_05922
gene_biotype: protein_coding
description:
  Putative transcriptional regulator, CopG family protein; COG0864 Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain.


ensembl_gene_id: PB1_05927
symbol: PB1_05927
gene_biotype: protein_coding
description:
  Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.


ensembl_gene_id: PB1_05937
symbol: acpS
gene_biotype: protein_coding
description:
  4'-phosphopantetheinyl transferase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.


ensembl_gene_id: PB1_05957
symbol: cshA
gene_biotype: protein_coding
description:
  DEAD/DEAH box helicase domain protein; DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA-dependent ATPase activity; Belongs to the DEAD box helicase family. CshA subfamily.


ensembl_gene_id: PB1_05972
symbol: murF
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.


ensembl_gene_id: PB1_05977
symbol: ddl
gene_biotype: protein_coding
description:
  D-alanyl-alanine synthetase A; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.


ensembl_gene_id: PB1_05987
symbol: PB1_05987
gene_biotype: protein_coding
description:
  Phosphoglycerate mutase; COG0406 Fructose-2,6-bisphosphatase; Belongs to the phosphoglycerate mutase family.


ensembl_gene_id: PB1_06007
symbol: PB1_06007
gene_biotype: protein_coding
description:
  Hypothetical protein; COG2087 Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase.


ensembl_gene_id: PB1_06017
symbol: cobS
gene_biotype: protein_coding
description:
  Cobalamin-5-phosphate synthase CobS; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.


ensembl_gene_id: PB1_06022
symbol: cobQ
gene_biotype: protein_coding
description:
  Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.


ensembl_gene_id: PB1_06027
symbol: PB1_06027
gene_biotype: protein_coding
description:
  Bifunctional adenosylcobalamin biosynthesis protein CobU; COG2087 Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase.


ensembl_gene_id: PB1_06032
symbol: PB1_06032
gene_biotype: protein_coding
description:
  Threonine-phosphate decarboxylase; COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase.


ensembl_gene_id: PB1_06037
symbol: cobD
gene_biotype: protein_coding
description:
  Cobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.


ensembl_gene_id: PB1_06042
symbol: PB1_06042
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components.


ensembl_gene_id: PB1_06047
symbol: PB1_06047
gene_biotype: protein_coding
description:
  Ferric ion ABC transporter; COG0609 ABC-type Fe3+-siderophore transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: PB1_06052
symbol: PB1_06052
gene_biotype: protein_coding
description:
  Periplasmic binding protein; COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component.


ensembl_gene_id: PB1_06067
symbol: PB1_06067
gene_biotype: protein_coding
description:
  MrgA; COG0783 DNA-binding ferritin-like protein (oxidative damage protectant); Belongs to the Dps family.


ensembl_gene_id: PB1_06087
symbol: PB1_06087
gene_biotype: protein_coding
description:
  Peptidase S8/S53 subtilisin kexin sedolisin; COG1404 Subtilisin-like serine proteases; Belongs to the peptidase S8 family.


ensembl_gene_id: PB1_06092
symbol: PB1_06092
gene_biotype: protein_coding
description:
  Two component transcriptional regulator, LytTR family protein; COG3279 Response regulator of the LytR/AlgR family.


ensembl_gene_id: PB1_06102
symbol: PB1_06102
gene_biotype: protein_coding
description:
  Two-component sensor histidine kinase/response regulator; COG0642 Signal transduction histidine kinase.


ensembl_gene_id: PB1_06167
symbol: kdpC
gene_biotype: protein_coding
description:
  Potassium-transporting ATPase C chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.


ensembl_gene_id: PB1_06172
symbol: PB1_06172
gene_biotype: protein_coding
description:
  Potassium-transporting ATPase B chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system.


ensembl_gene_id: PB1_06187
symbol: PB1_06187
gene_biotype: protein_coding
description:
  Gluconate kinase; COG1070 Sugar (pentulose and hexulose) kinases; Belongs to the FGGY kinase family.


ensembl_gene_id: PB1_06192
symbol: PB1_06192
gene_biotype: protein_coding
description:
  Thiamine/molybdopterin biosynthesis ThiF/MoeB-like protein; COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2.


ensembl_gene_id: PB1_06197
symbol: thiG
gene_biotype: protein_coding
description:
  Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.


ensembl_gene_id: PB1_06332
symbol: PB1_06332
gene_biotype: protein_coding
description:
  Peptide ABC transporter ATP-binding protein; COG1136 ABC-type antimicrobial peptide transport system, ATPase component.


ensembl_gene_id: PB1_06337
symbol: PB1_06337
gene_biotype: protein_coding
description:
  LuxR family two component transcriptional regulator; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: PB1_06372
symbol: glmS
gene_biotype: protein_coding
description:
  Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.


ensembl_gene_id: PB1_06387
symbol: glmM
gene_biotype: protein_coding
description:
  Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.


ensembl_gene_id: PB1_06397
symbol: dacA
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.


ensembl_gene_id: PB1_06407
symbol: PB1_06407
gene_biotype: protein_coding
description:
  COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: PB1_06417
symbol: rocF
gene_biotype: protein_coding
description:
  COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; Belongs to the arginase family.


ensembl_gene_id: PB1_06462
symbol: PB1_06462
gene_biotype: protein_coding
description:
  ATP-binding protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.


ensembl_gene_id: PB1_06482
symbol: rplM
gene_biotype: protein_coding
description:
  50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.


ensembl_gene_id: PB1_06487
symbol: truA
gene_biotype: protein_coding
description:
  tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.


ensembl_gene_id: PB1_06492
symbol: ecfT
gene_biotype: protein_coding
description:
  Cobalt transport protein; Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.


ensembl_gene_id: PB1_06512
symbol: rpoA
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: PB1_06517
symbol: rpsK
gene_biotype: protein_coding
description:
  30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.


ensembl_gene_id: PB1_06522
symbol: rpsM
gene_biotype: protein_coding
description:
  30S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family.


ensembl_gene_id: PB1_06532
symbol: infA
gene_biotype: protein_coding
description:
  Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.


ensembl_gene_id: PB1_06547
symbol: adk
gene_biotype: protein_coding
description:
  Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.


ensembl_gene_id: PB1_06552
symbol: secY
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.


ensembl_gene_id: PB1_06557
symbol: rplO
gene_biotype: protein_coding
description:
  50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.


ensembl_gene_id: PB1_06567
symbol: rpsE
gene_biotype: protein_coding
description:
  30S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.


ensembl_gene_id: PB1_06572
symbol: rplR
gene_biotype: protein_coding
description:
  50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.


ensembl_gene_id: PB1_06577
symbol: rplF
gene_biotype: protein_coding
description:
  50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.


ensembl_gene_id: PB1_06582
symbol: rpsH
gene_biotype: protein_coding
description:
  30S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.


ensembl_gene_id: PB1_06587
symbol: rpsN
gene_biotype: protein_coding
description:
  30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.


ensembl_gene_id: PB1_06592
symbol: rplE
gene_biotype: protein_coding
description:
  50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.


ensembl_gene_id: PB1_06597
symbol: rplX
gene_biotype: protein_coding
description:
  50S ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.


ensembl_gene_id: PB1_06602
symbol: rplN
gene_biotype: protein_coding
description:
  50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.


ensembl_gene_id: PB1_06607
symbol: rpsQ
gene_biotype: protein_coding
description:
  30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.


ensembl_gene_id: PB1_06617
symbol: rplP
gene_biotype: protein_coding
description:
  50S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.


ensembl_gene_id: PB1_06622
symbol: rpsC
gene_biotype: protein_coding
description:
  30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.


ensembl_gene_id: PB1_06627
symbol: rplV
gene_biotype: protein_coding
description:
  50S ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.


ensembl_gene_id: PB1_06632
symbol: rpsS
gene_biotype: protein_coding
description:
  30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.


ensembl_gene_id: PB1_06637
symbol: rplB
gene_biotype: protein_coding
description:
  50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.


ensembl_gene_id: PB1_06642
symbol: rplW
gene_biotype: protein_coding
description:
  50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.


ensembl_gene_id: PB1_06652
symbol: rplC
gene_biotype: protein_coding
description:
  50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.


ensembl_gene_id: PB1_06657
symbol: rpsJ
gene_biotype: protein_coding
description:
  30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.


ensembl_gene_id: PB1_06667
symbol: tuf
gene_biotype: protein_coding
description:
  Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.


ensembl_gene_id: PB1_06672
symbol: fusA
gene_biotype: protein_coding
description:
  Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.


ensembl_gene_id: PB1_06677
symbol: rpsG
gene_biotype: protein_coding
description:
  30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.


ensembl_gene_id: PB1_06682
symbol: rpsL
gene_biotype: protein_coding
description:
  30S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.


ensembl_gene_id: PB1_06687
symbol: PB1_06687
gene_biotype: protein_coding
description:
  COG1358 Ribosomal protein HS6-type (S12/L30/L7a); Belongs to the eukaryotic ribosomal protein eL8 family.


ensembl_gene_id: PB1_06692
symbol: rpoC
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: PB1_06697
symbol: rpoB
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: PB1_06707
symbol: rplL
gene_biotype: protein_coding
description:
  50S ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family.


ensembl_gene_id: PB1_06712
symbol: rplJ
gene_biotype: protein_coding
description:
  50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.


ensembl_gene_id: PB1_06717
symbol: rplA
gene_biotype: protein_coding
description:
  50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.


ensembl_gene_id: PB1_06722
symbol: rplK
gene_biotype: protein_coding
description:
  50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.


ensembl_gene_id: PB1_06727
symbol: nusG
gene_biotype: protein_coding
description:
  Transcription antitermination protein NusG; Participates in transcription elongation, termination and antitermination.


ensembl_gene_id: PB1_06732
symbol: secE
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.


ensembl_gene_id: PB1_06742
symbol: PB1_06742
gene_biotype: protein_coding
description:
  COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family.


ensembl_gene_id: PB1_06752
symbol: PB1_06752
gene_biotype: protein_coding
description:
  RNA methyltransferase, TrmH family, group 3; COG0566 rRNA methylases; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.


ensembl_gene_id: PB1_06757
symbol: mrnC
gene_biotype: protein_coding
description:
  Ribonuclease III; Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors; Belongs to the MrnC RNase family.


ensembl_gene_id: PB1_06772
symbol: gltX
gene_biotype: protein_coding
description:
  glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).


ensembl_gene_id: PB1_06777
symbol: ispF
gene_biotype: protein_coding
description:
  2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).


ensembl_gene_id: PB1_06782
symbol: ispD
gene_biotype: protein_coding
description:
  2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).


ensembl_gene_id: PB1_06792
symbol: disA
gene_biotype: protein_coding
description:
  DNA integrity scanning protein DisA; Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis.


ensembl_gene_id: PB1_06797
symbol: radA
gene_biotype: protein_coding
description:
  DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.


ensembl_gene_id: PB1_06802
symbol: PB1_06802
gene_biotype: protein_coding
description:
  Class III stress response-related ATPase, ClpC; COG0542 ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family.


ensembl_gene_id: PB1_06807
symbol: mcsB
gene_biotype: protein_coding
description:
  ATP:guanido phosphotransferase; Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity.


ensembl_gene_id: PB1_06812
symbol: PB1_06812
gene_biotype: protein_coding
description:
  Modulator of heat shock repressor CtsR, McsA; COG3880 Uncharacterized protein with conserved CXXC pairs.


ensembl_gene_id: PB1_06817
symbol: ctsR
gene_biotype: protein_coding
description:
  Transcriptional regulator CtsR; COG4463 Transcriptional repressor of class III stress genes; Belongs to the CtsR family.


ensembl_gene_id: PB1_06842
symbol: PB1_06842
gene_biotype: protein_coding
description:
  TIM-barrel protein, nifR3 family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.


ensembl_gene_id: PB1_06852
symbol: PB1_06852
gene_biotype: protein_coding
description:
  2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase.


ensembl_gene_id: PB1_06857
symbol: PB1_06857
gene_biotype: protein_coding
description:
  Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.


ensembl_gene_id: PB1_06862
symbol: PB1_06862
gene_biotype: protein_coding
description:
  Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.


ensembl_gene_id: PB1_06867
symbol: PB1_06867
gene_biotype: protein_coding
description:
  4-amino-4-deoxychorismate lyase; COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase.


ensembl_gene_id: PB1_06887
symbol: PB1_06887
gene_biotype: protein_coding
description:
  Putative PpiC-type peptidyl-prolyl cis-trans isomerase; COG0760 Parvulin-like peptidyl-prolyl isomerase.


ensembl_gene_id: PB1_06892
symbol: hslO
gene_biotype: protein_coding
description:
  Hsp33-like chaperonin; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.


ensembl_gene_id: PB1_06897
symbol: coaX
gene_biotype: protein_coding
description:
  Pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.


ensembl_gene_id: PB1_06902
symbol: ftsH
gene_biotype: protein_coding
description:
  ATP-dependent Zn protease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family.  In the central section; belongs to the AAA ATPase family.


ensembl_gene_id: PB1_06907
symbol: PB1_06907
gene_biotype: protein_coding
description:
  COG0634 Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.


ensembl_gene_id: PB1_06912
symbol: tilS
gene_biotype: protein_coding
description:
  tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.


ensembl_gene_id: PB1_06952
symbol: PB1_06952
gene_biotype: protein_coding
description:
  Ribosomal RNA binding protein; COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog); ribosomal RNA binding protein; heat shock protein.


ensembl_gene_id: PB1_06957
symbol: PB1_06957
gene_biotype: protein_coding
description:
  COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain.


ensembl_gene_id: PB1_06962
symbol: PB1_06962
gene_biotype: protein_coding
description:
  Polysaccharide biosynthesis protein; COG2244 Membrane protein involved in the export of O-antigen and teichoic acid.


ensembl_gene_id: PB1_06977
symbol: mfd
gene_biotype: protein_coding
description:
  Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.


ensembl_gene_id: PB1_06987
symbol: pth
gene_biotype: protein_coding
description:
  peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.


ensembl_gene_id: PB1_06992
symbol: rplY
gene_biotype: protein_coding
description:
  50S ribosomal protein L25/general stress protein Ctc; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.


ensembl_gene_id: PB1_06997
symbol: prs
gene_biotype: protein_coding
description:
  Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.


ensembl_gene_id: PB1_07002
symbol: glmU
gene_biotype: protein_coding
description:
  UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.


ensembl_gene_id: PB1_07007
symbol: spoVG
gene_biotype: protein_coding
description:
  Regulatory protein SpoVG; Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation.


ensembl_gene_id: PB1_07017
symbol: purR
gene_biotype: protein_coding
description:
  Pur operon repressor; COG0503 Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins.


ensembl_gene_id: PB1_07022
symbol: ispE
gene_biotype: protein_coding
description:
  4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.


ensembl_gene_id: PB1_07047
symbol: ksgA
gene_biotype: protein_coding
description:
  16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.


ensembl_gene_id: PB1_07052
symbol: rnmV
gene_biotype: protein_coding
description:
  Primase/topoisomerase like protein; Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.


ensembl_gene_id: PB1_07067
symbol: metG
gene_biotype: protein_coding
description:
  methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.


ensembl_gene_id: PB1_07072
symbol: abrB
gene_biotype: protein_coding
description:
  Transcriptional regulator, AbrB family protein; COG2002 Regulators of stationary/sporulation gene expression.


ensembl_gene_id: PB1_07077
symbol: rsmI
gene_biotype: protein_coding
description:
  uroporphyrin-III C/tetrapyrrole methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.


ensembl_gene_id: PB1_07092
symbol: PB1_07092
gene_biotype: protein_coding
description:
  DNA replication initiation control protein YabA; Involved in initiation control of chromosome replication. Belongs to the YabA family.


ensembl_gene_id: PB1_07122
symbol: tmk
gene_biotype: protein_coding
description:
  Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.


ensembl_gene_id: PB1_07152
symbol: PB1_07152
gene_biotype: protein_coding
description:
  UBA/THIF-type NAD/FAD binding protein; COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2.


ensembl_gene_id: PB1_07187
symbol: recR
gene_biotype: protein_coding
description:
  Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.


ensembl_gene_id: PB1_07192
symbol: PB1_07192
gene_biotype: protein_coding
description:
  Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.


ensembl_gene_id: PB1_07197
symbol: dnaX
gene_biotype: protein_coding
description:
  DNA polymerase III subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.


ensembl_gene_id: PB1_07202
symbol: tadA
gene_biotype: protein_coding
description:
  CMP/dCMP deaminase zinc-binding protein; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.


ensembl_gene_id: PB1_07222
symbol: serS
gene_biotype: protein_coding
description:
  seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).


ensembl_gene_id: PB1_07227
symbol: pdxT
gene_biotype: protein_coding
description:
  Glutamine amidotransferase subunit PdxT; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.


ensembl_gene_id: PB1_07232
symbol: pdxS
gene_biotype: protein_coding
description:
  Pyridoxal biosynthesis lyase PdxS; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family.


ensembl_gene_id: PB1_07237
symbol: PB1_07237
gene_biotype: protein_coding
description:
  Serine-type D-Ala-D-Ala carboxypeptidase; COG1686 D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family.


ensembl_gene_id: PB1_07242
symbol: guaB
gene_biotype: protein_coding
description:
  Inosine 5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.


ensembl_gene_id: PB1_07257
symbol: gyrA
gene_biotype: protein_coding
description:
  DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.


ensembl_gene_id: PB1_07262
symbol: gyrB
gene_biotype: protein_coding
description:
  DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.


ensembl_gene_id: PB1_07272
symbol: recF
gene_biotype: protein_coding
description:
  Recombination protein F; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family.


ensembl_gene_id: PB1_07282
symbol: PB1_07282
gene_biotype: protein_coding
description:
  DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of  [...]


ensembl_gene_id: PB1_07287
symbol: dnaA
gene_biotype: protein_coding
description:
  Chromosomal replication initiation protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.


ensembl_gene_id: PB1_07297
symbol: rnpA
gene_biotype: protein_coding
description:
  Ribonuclease P; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.


ensembl_gene_id: PB1_07302
symbol: yidC
gene_biotype: protein_coding
description:
  OxaA-like protein precursor; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins; Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily.


ensembl_gene_id: PB1_07312
symbol: mnmE
gene_biotype: protein_coding
description:
  tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.


ensembl_gene_id: PB1_07317
symbol: mnmG
gene_biotype: protein_coding
description:
  tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family.


ensembl_gene_id: PB1_07322
symbol: gidB
gene_biotype: protein_coding
description:
  16S rRNA methyltransferase GidB; Specifically methylates the N7 position of guanine in position 535 of 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.


ensembl_gene_id: PB1_07327
symbol: noc
gene_biotype: protein_coding
description:
  parB-like partition protein; Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage. Belongs to the ParB family.


ensembl_gene_id: PB1_07337
symbol: PB1_07337
gene_biotype: protein_coding
description:
  parB-like partition protein; COG1475 Predicted transcriptional regulators; Belongs to the ParB family.


ensembl_gene_id: PB1_07367
symbol: ychF
gene_biotype: protein_coding
description:
  GTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.


ensembl_gene_id: PB1_07377
symbol: PB1_07377
gene_biotype: protein_coding
description:
  alpha-D-mannose-alpha(1-6)phosphatidyl myo-inositol monomannoside transferase; COG0438 Glycosyltransferase.


ensembl_gene_id: PB1_07387
symbol: PB1_07387
gene_biotype: protein_coding
description:
  Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.


ensembl_gene_id: PB1_07392
symbol: rpsR
gene_biotype: protein_coding
description:
  30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.


ensembl_gene_id: PB1_07417
symbol: PB1_07417
gene_biotype: protein_coding
description:
  Hypothetical protein; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family.


ensembl_gene_id: PB1_07427
symbol: PB1_07427
gene_biotype: protein_coding
description:
  Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily.


ensembl_gene_id: PB1_07437
symbol: purA
gene_biotype: protein_coding
description:
  Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.


ensembl_gene_id: PB1_07452
symbol: yycF
gene_biotype: protein_coding
description:
  COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: PB1_07472
symbol: PB1_07472
gene_biotype: protein_coding
description:
  Beta-lactamase domain protein; COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I.


ensembl_gene_id: PB1_07477
symbol: PB1_07477
gene_biotype: protein_coding
description:
  Trypsin-like protein serine protease, contains C-terminal PDZ domain, Do-like protein; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain.


ensembl_gene_id: PB1_07487
symbol: rlmH
gene_biotype: protein_coding
description:
  rRNA large subunit methyltransferase; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family.


ensembl_gene_id: PB1_07542
symbol: PB1_07542
gene_biotype: protein_coding
description:
  Ferrichrome ABC transporter; COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components.


ensembl_gene_id: PB1_07547
symbol: PB1_07547
gene_biotype: protein_coding
description:
  COG0609 ABC-type Fe3+-siderophore transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: PB1_07552
symbol: PB1_07552
gene_biotype: protein_coding
description:
  FhuB; COG0609 ABC-type Fe3+-siderophore transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: PB1_07557
symbol: PB1_07557
gene_biotype: protein_coding
description:
  Ferrichrome ABC transporter ferrichrome-binding protein; COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component.


ensembl_gene_id: PB1_07562
symbol: PB1_07562
gene_biotype: protein_coding
description:
  Hypothetical protein; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: PB1_07602
symbol: PB1_07602
gene_biotype: protein_coding
description:
  COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases.


ensembl_gene_id: PB1_07622
symbol: pepT
gene_biotype: protein_coding
description:
  Peptidase T; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family.


ensembl_gene_id: PB1_07752
symbol: mobA
gene_biotype: protein_coding
description:
  Formate dehydrogenase family accessory protein FdhD; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.


ensembl_gene_id: PB1_07767
symbol: ung
gene_biotype: protein_coding
description:
  uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.


ensembl_gene_id: PB1_07797
symbol: PB1_07797
gene_biotype: protein_coding
description:
  Spore coat protein GerQ; Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA.


ensembl_gene_id: PB1_07812
symbol: lgt
gene_biotype: protein_coding
description:
  Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.


ensembl_gene_id: PB1_07817
symbol: PB1_07817
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases.


ensembl_gene_id: PB1_07827
symbol: PB1_07827
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase.


ensembl_gene_id: PB1_07842
symbol: lipL
gene_biotype: protein_coding
description:
  Lipoate-protein ligase A; Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes; Belongs to the octanoyltransferase LipL family.


ensembl_gene_id: PB1_07892
symbol: PB1_07892
gene_biotype: protein_coding
description:
  Penicillin-binding protein, 1A family; COG0744 Membrane carboxypeptidase (penicillin-binding protein).


ensembl_gene_id: PB1_07897
symbol: speE
gene_biotype: protein_coding
description:
  Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.


ensembl_gene_id: PB1_07902
symbol: PB1_07902
gene_biotype: protein_coding
description:
  Agmatinase; COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; Belongs to the arginase family.


ensembl_gene_id: PB1_07922
symbol: PB1_07922
gene_biotype: protein_coding
description:
  Phospholipase D/transphosphatidylase; COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipi n synthases and related enzymes; Belongs to the phospholipase D family. Cardiolipin synthase subfamily.


ensembl_gene_id: PB1_07957
symbol: mutB2
gene_biotype: protein_coding
description:
  methylmalonyl-CoA mutase, large subunit; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.


ensembl_gene_id: PB1_07967
symbol: rpoE
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase subunit delta; Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; Belongs to the RpoE family.


ensembl_gene_id: PB1_07972
symbol: pyrG
gene_biotype: protein_coding
description:
  CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.


ensembl_gene_id: PB1_07997
symbol: tal
gene_biotype: protein_coding
description:
  Translaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.


ensembl_gene_id: PB1_08002
symbol: murA
gene_biotype: protein_coding
description:
  UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.


ensembl_gene_id: PB1_08007
symbol: glpX2
gene_biotype: protein_coding
description:
  Fructose-bisphosphatase; COG1494 Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins.


ensembl_gene_id: PB1_08017
symbol: rho
gene_biotype: protein_coding
description:
  Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.


ensembl_gene_id: PB1_08042
symbol: prfA
gene_biotype: protein_coding
description:
  Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.


ensembl_gene_id: PB1_08047
symbol: prmC
gene_biotype: protein_coding
description:
  N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.


ensembl_gene_id: PB1_08057
symbol: PB1_08057
gene_biotype: protein_coding
description:
  sua5/yciO/yrdC/ywlC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.


ensembl_gene_id: PB1_08062
symbol: PB1_08062
gene_biotype: protein_coding
description:
  FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COG2072 Predicted flavoprotein involved in K+ transport.


ensembl_gene_id: PB1_08067
symbol: mntP
gene_biotype: protein_coding
description:
  Hypothetical protein; Probably functions as a manganese efflux pump. Belongs to the MntP (TC 9.B.29) family.


ensembl_gene_id: PB1_08097
symbol: glyA
gene_biotype: protein_coding
description:
  Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.


ensembl_gene_id: PB1_08102
symbol: upp
gene_biotype: protein_coding
description:
  Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.


ensembl_gene_id: PB1_08127
symbol: atpB
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit A; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family.


ensembl_gene_id: PB1_08132
symbol: atpE
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit C; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.


ensembl_gene_id: PB1_08137
symbol: atpF
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit B; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family.


ensembl_gene_id: PB1_08142
symbol: atpH
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit delta; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.


ensembl_gene_id: PB1_08147
symbol: atpA
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.


ensembl_gene_id: PB1_08152
symbol: atpG
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit gamma; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.


ensembl_gene_id: PB1_08157
symbol: atpD
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.


ensembl_gene_id: PB1_08162
symbol: atpC
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit epsilon; Produces ATP from ADP in the presence of a proton gradient across the membrane.


ensembl_gene_id: PB1_08167
symbol: nuoA
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit A; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family.


ensembl_gene_id: PB1_08172
symbol: nuoB
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit B; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: PB1_08182
symbol: nuoD
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family.


ensembl_gene_id: PB1_08187
symbol: nuoH
gene_biotype: protein_coding
description:
  NADH:ubiquinone oxidoreductase subunit H; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.


ensembl_gene_id: PB1_08192
symbol: nuoI
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: PB1_08197
symbol: PB1_08197
gene_biotype: protein_coding
description:
  NADH:ubiquinone oxidoreductase subunit J; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: PB1_08202
symbol: nuoK
gene_biotype: protein_coding
description:
  NADH:ubiquinone oxidoreductase subunit K; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family.


ensembl_gene_id: PB1_08207
symbol: PB1_08207
gene_biotype: protein_coding
description:
  COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit.


ensembl_gene_id: PB1_08217
symbol: nuoN
gene_biotype: protein_coding
description:
  NADH:ubiquinone oxidoreductase subunit N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family.


ensembl_gene_id: PB1_08282
symbol: fabZ
gene_biotype: protein_coding
description:
  (3R)-hydroxymyristoyl-ACP dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.


ensembl_gene_id: PB1_08322
symbol: PB1_08322
gene_biotype: protein_coding
description:
  NADP-dependent glyceraldehyde-3-phosphate dehydrogenase; COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: PB1_08357
symbol: PB1_08357
gene_biotype: protein_coding
description:
  Putative ATP-binding SNF2 helicase or protein kinase; COG0553 Superfamily II DNA/RNA helicases, SNF2 family.


ensembl_gene_id: PB1_08377
symbol: PB1_08377
gene_biotype: protein_coding
description:
  Carboxyl-terminal processing protease; COG0793 Periplasmic protease; Belongs to the peptidase S41A family.


ensembl_gene_id: PB1_08532
symbol: PB1_08532
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog.


ensembl_gene_id: PB1_08577
symbol: PB1_08577
gene_biotype: protein_coding
description:
  Metallophosphoesterase; COG4632 Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase.


ensembl_gene_id: PB1_08587
symbol: PB1_08587
gene_biotype: protein_coding
description:
  Urea ABC transporter, urea binding protein; COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component.


ensembl_gene_id: PB1_08592
symbol: PB1_08592
gene_biotype: protein_coding
description:
  Urea ABC transporter, permease protein UrtB; COG0559 Branched-chain amino acid ABC-type transport system, permease components; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: PB1_08597
symbol: PB1_08597
gene_biotype: protein_coding
description:
  Urea ABC transporter, permease protein UrtC; COG4177 ABC-type branched-chain amino acid transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: PB1_08602
symbol: PB1_08602
gene_biotype: protein_coding
description:
  Urea ABC transporter, ATP-binding protein UrtD; COG4674 Uncharacterized ABC-type transport system, ATPase component.


ensembl_gene_id: PB1_08607
symbol: PB1_08607
gene_biotype: protein_coding
description:
  Urea ABC transporter, ATP-binding protein UrtE; COG0410 ABC-type branched-chain amino acid transport systems, ATPase component.


ensembl_gene_id: PB1_08612
symbol: ureA
gene_biotype: protein_coding
description:
  Urease, gamma subunit; COG0831 Urea amidohydrolase (urease) gamma subunit; Belongs to the urease gamma subunit family.


ensembl_gene_id: PB1_08617
symbol: ureB
gene_biotype: protein_coding
description:
  Urease subunit beta; COG0832 Urea amidohydrolase (urease) beta subunit; Belongs to the urease beta subunit family.


ensembl_gene_id: PB1_08627
symbol: ureE
gene_biotype: protein_coding
description:
  Urease accessory protein UreE; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family.


ensembl_gene_id: PB1_08632
symbol: ureF
gene_biotype: protein_coding
description:
  Urease accessory protein UreF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.


ensembl_gene_id: PB1_08637
symbol: ureG
gene_biotype: protein_coding
description:
  Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.


ensembl_gene_id: PB1_08642
symbol: ureD
gene_biotype: protein_coding
description:
  Urease accessory protein UreD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.


ensembl_gene_id: PB1_08667
symbol: mtaD
gene_biotype: protein_coding
description:
  N-ethylammeline chlorohydrolase; Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.


ensembl_gene_id: PB1_08687
symbol: PB1_08687
gene_biotype: protein_coding
description:
  Binding-protein-dependent transport systems inner membrane component; COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component.


ensembl_gene_id: PB1_08692
symbol: PB1_08692
gene_biotype: protein_coding
description:
  NMT1/THI5 like domain protein; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components.


ensembl_gene_id: PB1_08707
symbol: PB1_08707
gene_biotype: protein_coding
description:
  Molybdopterin dehydrogenase FAD-binding protein; COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs.


ensembl_gene_id: PB1_08712
symbol: PB1_08712
gene_biotype: protein_coding
description:
  Xanthine dehydrogenase, substrate and molybdenum cofactor subunit; COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs.


ensembl_gene_id: PB1_08722
symbol: PB1_08722
gene_biotype: protein_coding
description:
  COG2351 Transthyretin-like protein; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.


ensembl_gene_id: PB1_08732
symbol: PB1_08732
gene_biotype: protein_coding
description:
  Transcriptional regulator of the purine degradation operon; COG2508 Regulator of polyketide synthase expression.


ensembl_gene_id: PB1_08737
symbol: PB1_08737
gene_biotype: protein_coding
description:
  Allantoate amidohydrolase; COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases.


ensembl_gene_id: PB1_08742
symbol: PB1_08742
gene_biotype: protein_coding
description:
  Aminotransferase, class V family protein; COG0075 Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase.


ensembl_gene_id: PB1_08747
symbol: PB1_08747
gene_biotype: protein_coding
description:
  Nitrate/sulfonate/bicarbonate ABC transporter ATP-binding protein; COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component.


ensembl_gene_id: PB1_08757
symbol: PB1_08757
gene_biotype: protein_coding
description:
  Nitrate/sulfonate/bicarbonate ABC transporter substrate-binding protein; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components.


ensembl_gene_id: PB1_08812
symbol: PB1_08812
gene_biotype: protein_coding
description:
  COG0685 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.


ensembl_gene_id: PB1_08822
symbol: PB1_08822
gene_biotype: protein_coding
description:
  Phosphoribosylformylglycinamidine synthase II related protein; COG2144 Selenophosphate synthetase-related proteins.


ensembl_gene_id: PB1_08867
symbol: PB1_08867
gene_biotype: protein_coding
description:
  COG1191 DNA-directed RNA polymerase specialized sigma subunit; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: PB1_08872
symbol: PB1_08872
gene_biotype: protein_coding
description:
  Hypothetical protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.


ensembl_gene_id: PB1_08947
symbol: PB1_08947
gene_biotype: protein_coding
description:
  Alginate O-acetyltransferase; COG1696 Predicted membrane protein involved in D-alanine export; Belongs to the membrane-bound acyltransferase family.


ensembl_gene_id: PB1_08962
symbol: PB1_08962
gene_biotype: protein_coding
description:
  Hypothetical protein; COG4632 Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase.


ensembl_gene_id: PB1_08987
symbol: secA
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.


ensembl_gene_id: PB1_09002
symbol: PB1_09002
gene_biotype: protein_coding
description:
  Glycosyl transferase, family 4, conserved region protein; COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase.


ensembl_gene_id: PB1_09007
symbol: PB1_09007
gene_biotype: protein_coding
description:
  Pleiotropic regulatory protein; COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; Belongs to the DegT/DnrJ/EryC1 family.


ensembl_gene_id: PB1_09022
symbol: PB1_09022
gene_biotype: protein_coding
description:
  Nucleotide sugar dehydrogenase; COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.


ensembl_gene_id: PB1_09037
symbol: PB1_09037
gene_biotype: protein_coding
description:
  COG0381 UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family.


ensembl_gene_id: PB1_09097
symbol: PB1_09097
gene_biotype: protein_coding
description:
  Two-component sensor histidine kinase DegS; Member of the two-component regulatory system DegS/DegU, which plays an important role in the transition growth phase.


ensembl_gene_id: PB1_09117
symbol: PB1_09117
gene_biotype: protein_coding
description:
  Helicase domain protein; COG4098 Superfamily II DNA/RNA helicase required for DNA uptake (late competence protein).


ensembl_gene_id: PB1_09127
symbol: PB1_09127
gene_biotype: protein_coding
description:
  Membrane protein; COG1594 DNA-directed RNA polymerase, subunit M/Transcription elongation factor TFIIS.


ensembl_gene_id: PB1_09132
symbol: PB1_09132
gene_biotype: protein_coding
description:
  Anti-sigma-28 factor FlgM family protein; COG2747 Negative regulator of flagellin synthesis (anti-sigma28 factor).


ensembl_gene_id: PB1_09157
symbol: fliW
gene_biotype: protein_coding
description:
  Hypothetical protein; Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.


ensembl_gene_id: PB1_09162
symbol: csrA
gene_biotype: protein_coding
description:
  Carbon storage regulator; A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'- UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.


ensembl_gene_id: PB1_09167
symbol: PB1_09167
gene_biotype: protein_coding
description:
  Flagellin domain protein; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.


ensembl_gene_id: PB1_09192
symbol: PB1_09192
gene_biotype: protein_coding
description:
  DegT/DnrJ/EryC1/StrS aminotransferase; COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; Belongs to the DegT/DnrJ/EryC1 family.


ensembl_gene_id: PB1_09252
symbol: PB1_09252
gene_biotype: protein_coding
description:
  Short chain dehydrogenase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: PB1_09272
symbol: fliD
gene_biotype: protein_coding
description:
  Flagellar capping protein; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.


ensembl_gene_id: PB1_09292
symbol: hpf
gene_biotype: protein_coding
description:
  Sigma 54 modulation protein/ribosomal protein S30EA; Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.


ensembl_gene_id: PB1_09317
symbol: secA-2
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family.


ensembl_gene_id: PB1_09322
symbol: prfB
gene_biotype: protein_coding
description:
  Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.


ensembl_gene_id: PB1_09347
symbol: ftsE
gene_biotype: protein_coding
description:
  Cell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division.


ensembl_gene_id: PB1_09352
symbol: PB1_09352
gene_biotype: protein_coding
description:
  Cell division protein; Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation. Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.


ensembl_gene_id: PB1_09382
symbol: PB1_09382
gene_biotype: protein_coding
description:
  Cell division topological determinant; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain.


ensembl_gene_id: PB1_09412
symbol: PB1_09412
gene_biotype: protein_coding
description:
  Acriflavin resistance protein; COG0841 Cation/multidrug efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: PB1_09422
symbol: uvrB
gene_biotype: protein_coding
description:
  Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate  [...]


ensembl_gene_id: PB1_09427
symbol: uvrA
gene_biotype: protein_coding
description:
  Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.


ensembl_gene_id: PB1_09472
symbol: nagB
gene_biotype: protein_coding
description:
  Glucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.


ensembl_gene_id: PB1_09477
symbol: hprK
gene_biotype: protein_coding
description:
  HPr kinase/phosphorylase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon [...]


ensembl_gene_id: PB1_09492
symbol: ppaX
gene_biotype: protein_coding
description:
  Pyrophosphatase PpaX; Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK/P. Might play a role in controlling the intracellular pyrophosphate pool.


ensembl_gene_id: PB1_09502
symbol: hisZ
gene_biotype: protein_coding
description:
  ATP phosphoribosyltransferase regulatory subunit; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.


ensembl_gene_id: PB1_09507
symbol: hisG
gene_biotype: protein_coding
description:
  ATP phosphoribosyltransferase catalytic subunit; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily.


ensembl_gene_id: PB1_09512
symbol: hisD
gene_biotype: protein_coding
description:
  Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.


ensembl_gene_id: PB1_09522
symbol: hisH
gene_biotype: protein_coding
description:
  Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.


ensembl_gene_id: PB1_09527
symbol: hisA
gene_biotype: protein_coding
description:
  1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; COG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase.


ensembl_gene_id: PB1_09532
symbol: hisF
gene_biotype: protein_coding
description:
  Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.


ensembl_gene_id: PB1_09537
symbol: hisI
gene_biotype: protein_coding
description:
  Bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; COG0139 Phosphoribosyl-AMP cyclohydrolase; In the N-terminal section; belongs to the PRA-CH family.


ensembl_gene_id: PB1_09562
symbol: PB1_09562
gene_biotype: protein_coding
description:
  Hypothetical protein; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family.


ensembl_gene_id: PB1_09577
symbol: clpP
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.


ensembl_gene_id: PB1_09597
symbol: cggR
gene_biotype: protein_coding
description:
  Transcriptional regulator, DeoR family protein; COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain.


ensembl_gene_id: PB1_09602
symbol: PB1_09602
gene_biotype: protein_coding
description:
  COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.


ensembl_gene_id: PB1_09612
symbol: tpiA
gene_biotype: protein_coding
description:
  Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.


ensembl_gene_id: PB1_09617
symbol: gpmI
gene_biotype: protein_coding
description:
  Phosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the BPG-independent phosphoglycerate mutase family.


ensembl_gene_id: PB1_09622
symbol: eno
gene_biotype: protein_coding
description:
  Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.


ensembl_gene_id: PB1_09627
symbol: secG
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.


ensembl_gene_id: PB1_09637
symbol: rnr
gene_biotype: protein_coding
description:
  Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.


ensembl_gene_id: PB1_09642
symbol: smpB
gene_biotype: protein_coding
description:
  SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]


ensembl_gene_id: PB1_09657
symbol: PB1_09657
gene_biotype: protein_coding
description:
  Luciferase-type oxidoreductase; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: PB1_09662
symbol: mnmA
gene_biotype: protein_coding
description:
  tRNA-specific 2-thiouridylase MnmA; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.


ensembl_gene_id: PB1_09672
symbol: nadE
gene_biotype: protein_coding
description:
  NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family.


ensembl_gene_id: PB1_09717
symbol: PB1_09717
gene_biotype: protein_coding
description:
  Sporulation-specific ATP-dependent protein histidine kinase; COG0642 Signal transduction histidine kinase.


ensembl_gene_id: PB1_09727
symbol: corA
gene_biotype: protein_coding
description:
  Magnesium and cobalt transport protein CorA; Mediates influx of magnesium ions. Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.


ensembl_gene_id: PB1_09782
symbol: PB1_09782
gene_biotype: protein_coding
description:
  Fe3+-siderophore achromobactin ABC transporter periplasmic protein; COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component.


ensembl_gene_id: PB1_09787
symbol: PB1_09787
gene_biotype: protein_coding
description:
  YfiZ; COG0609 ABC-type Fe3+-siderophore transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: PB1_09842
symbol: PB1_09842
gene_biotype: protein_coding
description:
  YusI; COG1393 Arsenate reductase and related proteins, glutaredoxin family; Belongs to the ArsC family.


ensembl_gene_id: PB1_09847
symbol: gcvH
gene_biotype: protein_coding
description:
  Glycine cleavage system protein H; Is also involved in protein lipoylation via its role as an octanoyl/lipoyl carrier protein intermediate; Belongs to the GcvH family.


ensembl_gene_id: PB1_09867
symbol: metN-2
gene_biotype: protein_coding
description:
  ABC transporter related protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.


ensembl_gene_id: PB1_09872
symbol: PB1_09872
gene_biotype: protein_coding
description:
  Methionine import ABC transporter permease MetP; COG2011 ABC-type metal ion transport system, permease component.


ensembl_gene_id: PB1_09887
symbol: PB1_09887
gene_biotype: protein_coding
description:
  FeS assembly ATPase SufC; COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component.


ensembl_gene_id: PB1_09897
symbol: PB1_09897
gene_biotype: protein_coding
description:
  Csd; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.


ensembl_gene_id: PB1_09902
symbol: PB1_09902
gene_biotype: protein_coding
description:
  SUF system FeS assembly protein, NifU family; COG0822 NifU homolog involved in Fe-S cluster formation.


ensembl_gene_id: PB1_09917
symbol: PB1_09917
gene_biotype: protein_coding
description:
  Metallophosphoesterase; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family.


ensembl_gene_id: PB1_09932
symbol: PB1_09932
gene_biotype: protein_coding
description:
  ABC transporter related protein; COG0411 ABC-type branched-chain amino acid transport systems, ATPase component.


ensembl_gene_id: PB1_09937
symbol: PB1_09937
gene_biotype: protein_coding
description:
  COG4177 ABC-type branched-chain amino acid transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: PB1_09942
symbol: PB1_09942
gene_biotype: protein_coding
description:
  COG0559 Branched-chain amino acid ABC-type transport system, permease components; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: PB1_09957
symbol: lipA
gene_biotype: protein_coding
description:
  Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.


ensembl_gene_id: PB1_09987
symbol: PB1_09987
gene_biotype: protein_coding
description:
  HAD-superfamily subfamily IIA hydrolase like protein; COG0647 Predicted sugar phosphatases of the HAD superfamily.


ensembl_gene_id: PB1_10007
symbol: thrC
gene_biotype: protein_coding
description:
  Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.


ensembl_gene_id: PB1_10012
symbol: thrB
gene_biotype: protein_coding
description:
  Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.


ensembl_gene_id: PB1_10037
symbol: PB1_10037
gene_biotype: protein_coding
description:
  FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COG1252 NADH dehydrogenase, FAD-containing subunit.


ensembl_gene_id: PB1_10067
symbol: PB1_10067
gene_biotype: protein_coding
description:
  Mutt/nudix family protein; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; Belongs to the Nudix hydrolase family.


ensembl_gene_id: PB1_10092
symbol: pepA
gene_biotype: protein_coding
description:
  Leucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.


ensembl_gene_id: PB1_10127
symbol: PB1_10127
gene_biotype: protein_coding
description:
  Thioesterase superfamily protein; COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism.


ensembl_gene_id: PB1_10132
symbol: PB1_10132
gene_biotype: protein_coding
description:
  Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.


ensembl_gene_id: PB1_10142
symbol: PB1_10142
gene_biotype: protein_coding
description:
  Cu/Zn superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family.


ensembl_gene_id: PB1_10172
symbol: PB1_10172
gene_biotype: protein_coding
description:
  General stress protein 13; COG1098 Predicted RNA binding protein (contains ribosomal protein S1 domain).


ensembl_gene_id: PB1_10187
symbol: PB1_10187
gene_biotype: protein_coding
description:
  Iron-containing alcohol dehydrogenase; COG1979 Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family.


ensembl_gene_id: PB1_10222
symbol: azoR
gene_biotype: protein_coding
description:
  Azoreductase; Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity; Belongs to the azoreductase type 1 family.


ensembl_gene_id: PB1_10232
symbol: PB1_10232
gene_biotype: protein_coding
description:
  Ribonucleotide-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.


ensembl_gene_id: PB1_10237
symbol: nrdF
gene_biotype: protein_coding
description:
  Ribonucleotide-diphosphate reductase subunit beta; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.


ensembl_gene_id: PB1_10389
symbol: PB1_10389
gene_biotype: protein_coding
description:
  CoA-substrate-specific enzyme activase; COG1924 Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain).


ensembl_gene_id: PB1_10394
symbol: PB1_10394
gene_biotype: protein_coding
description:
  Activator of 2-hydroxyglutaryl-CoA dehydratase; COG3581 Uncharacterized protein conserved in bacteria.


ensembl_gene_id: PB1_10409
symbol: PB1_10409
gene_biotype: protein_coding
description:
  Putative PTS IIA-like nitrogen-regulatory protein PtsN; COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type).


ensembl_gene_id: PB1_10444
symbol: mtnA
gene_biotype: protein_coding
description:
  Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.


ensembl_gene_id: PB1_10494
symbol: nnrE
gene_biotype: protein_coding
description:
  Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.  Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...]


ensembl_gene_id: PB1_10504
symbol: plsY
gene_biotype: protein_coding
description:
  Putative glycerol-3-phosphate acyltransferase PlsY; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.


ensembl_gene_id: PB1_10509
symbol: PB1_10509
gene_biotype: protein_coding
description:
  Amidase; COG0154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases; Belongs to the amidase family.


ensembl_gene_id: PB1_10524
symbol: PB1_10524
gene_biotype: protein_coding
description:
  Hypothetical protein; COG3858 Predicted glycosyl hydrolase; Belongs to the glycosyl hydrolase 18 family.


ensembl_gene_id: PB1_10534
symbol: parE
gene_biotype: protein_coding
description:
  DNA topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 2 subfamily.


ensembl_gene_id: PB1_10539
symbol: parC
gene_biotype: protein_coding
description:
  DNA topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 2 subfamily.


ensembl_gene_id: PB1_10589
symbol: cas2
gene_biotype: protein_coding
description:
  Hypothetical protein; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.


ensembl_gene_id: PB1_10594
symbol: cas1
gene_biotype: protein_coding
description:
  CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.


ensembl_gene_id: PB1_10599
symbol: PB1_10599
gene_biotype: protein_coding
description:
  RecB family exonuclease; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Belongs to the CRISPR-associated exonuclease Cas4 family.


ensembl_gene_id: PB1_10719
symbol: PB1_10719
gene_biotype: protein_coding
description:
  Regulator of chromosome condensation-like protein; COG5184 Alpha-tubulin suppressor and related RCC1 domain-containing proteins.


ensembl_gene_id: PB1_10739
symbol: PB1_10739
gene_biotype: protein_coding
description:
  Glycosyl transferase family 2 protein; COG0463 Glycosyltransferases involved in cell wall biogenesis.


ensembl_gene_id: PB1_10864
symbol: PB1_10864
gene_biotype: protein_coding
description:
  ABC transporter related protein; COG1119 ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA.


ensembl_gene_id: PB1_10894
symbol: PB1_10894
gene_biotype: protein_coding
description:
  Acetyltransferase; COG1246 N-acetylglutamate synthase and related acetyltransferases; Belongs to the acetyltransferase family.


ensembl_gene_id: PB1_10919
symbol: ssuB
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system.


ensembl_gene_id: PB1_10929
symbol: ssuD
gene_biotype: protein_coding
description:
  Aliphatic sulfonate monooxygenase; Catalyzes the desulfonation of aliphatic sulfonates. Belongs to the SsuD family.


ensembl_gene_id: PB1_10934
symbol: PB1_10934
gene_biotype: protein_coding
description:
  Aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components.


ensembl_gene_id: PB1_10974
symbol: cysA
gene_biotype: protein_coding
description:
  Sulfate ABC transporter ATP-binding protein CysA; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system.


ensembl_gene_id: PB1_10984
symbol: PB1_10984
gene_biotype: protein_coding
description:
  Sulfate ABC transporter permease CysT; Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.


ensembl_gene_id: PB1_10994
symbol: PB1_10994
gene_biotype: protein_coding
description:
  Putative sulfate ABC transporter sulfate-binding protein; COG1613 ABC-type sulfate transport system, periplasmic component.


ensembl_gene_id: PB1_11049
symbol: PB1_11049
gene_biotype: protein_coding
description:
  Glyoxalase/bleomycin resistance protein/dioxygenase; COG0346 Lactoylglutathione lyase and related lyases.


ensembl_gene_id: PB1_11094
symbol: bioA
gene_biotype: protein_coding
description:
  Adenosylmethionine--8-amino-7-oxononanoate transaminase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.


ensembl_gene_id: PB1_11139
symbol: bioB
gene_biotype: protein_coding
description:
  Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.


ensembl_gene_id: PB1_11149
symbol: PB1_11149
gene_biotype: protein_coding
description:
  Oxidoreductase family, NAD-binding Rossmann fold protein; COG0673 Predicted dehydrogenases and related proteins.


ensembl_gene_id: PB1_11159
symbol: PB1_11159
gene_biotype: protein_coding
description:
  Putative zinc-type alcohol dehydrogenase-like protein; COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases.


ensembl_gene_id: PB1_11169
symbol: PB1_11169
gene_biotype: protein_coding
description:
  Ribose transport ATP-binding protein rbsA; COG1129 ABC-type sugar transport system, ATPase component.


ensembl_gene_id: PB1_11189
symbol: bioD
gene_biotype: protein_coding
description:
  Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.


ensembl_gene_id: PB1_11229
symbol: PB1_11229
gene_biotype: protein_coding
description:
  Putative factor for cell wall maintenance or synthesis; COG2720 Uncharacterized vancomycin resistance protein.


ensembl_gene_id: PB1_11349
symbol: PB1_11349
gene_biotype: protein_coding
description:
  2Fe-2S iron-sulfur cluster binding domain-containing protein; COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs.


ensembl_gene_id: PB1_11369
symbol: PB1_11369
gene_biotype: protein_coding
description:
  Lipoprotein; COG1999 Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems.


ensembl_gene_id: PB1_11394
symbol: PB1_11394
gene_biotype: protein_coding
description:
  Molybdenum ABC transporter permease; Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: PB1_11429
symbol: crcB
gene_biotype: protein_coding
description:
  Hypothetical protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.


ensembl_gene_id: PB1_11459
symbol: odhB
gene_biotype: protein_coding
description:
  Dihydrolipoyllysine-residue succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).


ensembl_gene_id: PB1_11464
symbol: odhA
gene_biotype: protein_coding
description:
  Oxoglutarate dehydrogenase (succinyl-transferring); E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).


ensembl_gene_id: PB1_11489
symbol: PB1_11489
gene_biotype: protein_coding
description:
  COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; Belongs to the bacterial solute-binding protein 3 family.


ensembl_gene_id: PB1_11524
symbol: PB1_11524
gene_biotype: protein_coding
description:
  methylated-DNA--protein-cysteine S-methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.


ensembl_gene_id: PB1_11534
symbol: PB1_11534
gene_biotype: protein_coding
description:
  GNAT family acetyltransferase; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases.


ensembl_gene_id: PB1_11579
symbol: PB1_11579
gene_biotype: protein_coding
description:
  NlpA lipoprotein; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components.


ensembl_gene_id: PB1_11599
symbol: PB1_11599
gene_biotype: protein_coding
description:
  Homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein; COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain.


ensembl_gene_id: PB1_11604
symbol: PB1_11604
gene_biotype: protein_coding
description:
  Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.


ensembl_gene_id: PB1_11629
symbol: metE
gene_biotype: protein_coding
description:
  5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.


ensembl_gene_id: PB1_11694
symbol: PB1_11694
gene_biotype: protein_coding
description:
  Proton/glutamate symporter family protein; COG1301 Na+/H+-dicarboxylate symporters; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: PB1_11719
symbol: fdhA
gene_biotype: protein_coding
description:
  Formate dehydrogenase alpha chain; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: PB1_11724
symbol: fdhD
gene_biotype: protein_coding
description:
  Formate dehydrogenase family accessory protein; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.


ensembl_gene_id: PB1_11734
symbol: PB1_11734
gene_biotype: protein_coding
description:
  Binding-protein-dependent transport systems inner membrane component; COG2011 ABC-type metal ion transport system, permease component.


ensembl_gene_id: PB1_11739
symbol: metN
gene_biotype: protein_coding
description:
  DL-methionine transporter ATP-binding subunit; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.


ensembl_gene_id: PB1_11759
symbol: PB1_11759
gene_biotype: protein_coding
description:
  NUDIX family hydrolase; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes.


ensembl_gene_id: PB1_11774
symbol: PB1_11774
gene_biotype: protein_coding
description:
  L,D-carboxypeptidase; COG1619 Uncharacterized proteins, homologs of microcin C7 resistance protein MccF.


ensembl_gene_id: PB1_11779
symbol: proA
gene_biotype: protein_coding
description:
  Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.


ensembl_gene_id: PB1_11784
symbol: proB
gene_biotype: protein_coding
description:
  Gamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.


ensembl_gene_id: PB1_11804
symbol: PB1_11804
gene_biotype: protein_coding
description:
  Extracellular solute-binding protein family 1; COG0687 Spermidine/putrescine-binding periplasmic protein.


ensembl_gene_id: PB1_11819
symbol: PB1_11819
gene_biotype: protein_coding
description:
  Binding-protein-dependent transport systems inner membrane component; COG1176 ABC-type spermidine/putrescine transport system, permease component I.


ensembl_gene_id: PB1_11824
symbol: potA
gene_biotype: protein_coding
description:
  ABC transporter related protein; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.


ensembl_gene_id: PB1_11839
symbol: rbsK
gene_biotype: protein_coding
description:
  Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.


ensembl_gene_id: PB1_11849
symbol: PB1_11849
gene_biotype: protein_coding
description:
  Dyp-type peroxidase family protein; Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the tetrapyrrol ring intact. Belongs to the DyP-type peroxidase family.


ensembl_gene_id: PB1_11889
symbol: PB1_11889
gene_biotype: protein_coding
description:
  Bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP; Belongs to the PRA-CH family.


ensembl_gene_id: PB1_11899
symbol: PB1_11899
gene_biotype: protein_coding
description:
  Putative nicotinate phosphoribosyltransferase; COG1488 Nicotinic acid phosphoribosyltransferase; Belongs to the NAPRTase family.


ensembl_gene_id: PB1_11909
symbol: menC
gene_biotype: protein_coding
description:
  O-succinylbenzoic acid (OSB) synthetase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB).


ensembl_gene_id: PB1_11959
symbol: PB1_11959
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component.


ensembl_gene_id: PB1_12009
symbol: queE
gene_biotype: protein_coding
description:
  Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.


ensembl_gene_id: PB1_12019
symbol: queC
gene_biotype: protein_coding
description:
  Queuosine biosynthesis protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).


ensembl_gene_id: PB1_12024
symbol: PB1_12024
gene_biotype: protein_coding
description:
  Molybdopterin oxidoreductase; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: PB1_12029
symbol: PB1_12029
gene_biotype: protein_coding
description:
  Non specific extracellular endonuclease cleaving RNA and DNA; COG1525 Micrococcal nuclease (thermonuclease) homologs.


ensembl_gene_id: PB1_12054
symbol: trpB
gene_biotype: protein_coding
description:
  Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.


ensembl_gene_id: PB1_12149
symbol: PB1_12149
gene_biotype: protein_coding
description:
  Aliphatic sulfonates family ABC transporter, periplasmic ligand-binding protein; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components.


ensembl_gene_id: PB1_12259
symbol: PB1_12259
gene_biotype: protein_coding
description:
  DNA-cytosine methyltransferase; COG0270 Site-specific DNA methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.


ensembl_gene_id: PB1_12304
symbol: rbsK-2
gene_biotype: protein_coding
description:
  Sugar kinase, ribokinase family protein; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.


ensembl_gene_id: PB1_12319
symbol: deoC
gene_biotype: protein_coding
description:
  Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.


ensembl_gene_id: PB1_12374
symbol: PB1_12374
gene_biotype: protein_coding
description:
  Na(+)/H(+)-K(+) antiporter; COG0475 Kef-type K+ transport systems, membrane components; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.


ensembl_gene_id: PB1_12389
symbol: PB1_12389
gene_biotype: protein_coding
description:
  Cytochrome aa3 quinol oxidase subunit II; Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I.


ensembl_gene_id: PB1_12484
symbol: merA
gene_biotype: protein_coding
description:
  Mercuric reductase; Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0). Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.


ensembl_gene_id: PB1_12504
symbol: PB1_12504
gene_biotype: protein_coding
description:
  Arsenical pump membrane protein; Involved in arsenical resistance. Thought to form the channel of an arsenite pump; Belongs to the ArsB family.


ensembl_gene_id: PB1_12534
symbol: mntH
gene_biotype: protein_coding
description:
  Manganese transport protein MntH; H(+)-stimulated, divalent metal cation uptake system. Belongs to the NRAMP family.


ensembl_gene_id: PB1_12609
symbol: PB1_12609
gene_biotype: protein_coding
description:
  PTS system ascorbate-specific transporter subunit IIC; COG3037 Uncharacterized protein conserved in bacteria.


ensembl_gene_id: PB1_12619
symbol: PB1_12619
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type).


ensembl_gene_id: PB1_12624
symbol: abrB2
gene_biotype: protein_coding
description:
  AbrB family transcriptional regulator; COG2002 Regulators of stationary/sporulation gene expression.


ensembl_gene_id: PB1_12664
symbol: PB1_12664
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component.


ensembl_gene_id: PB1_12679
symbol: PB1_12679
gene_biotype: protein_coding
description:
  ABC transporter substrate-binding protein; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components.


ensembl_gene_id: PB1_12764
symbol: trpA
gene_biotype: protein_coding
description:
  Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.


ensembl_gene_id: PB1_12784
symbol: trpD
gene_biotype: protein_coding
description:
  Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).


ensembl_gene_id: PB1_12794
symbol: trpE
gene_biotype: protein_coding
description:
  Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...]


ensembl_gene_id: PB1_12799
symbol: PB1_12799
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases.


ensembl_gene_id: PB1_12839
symbol: PB1_12839
gene_biotype: protein_coding
description:
  Putative 1-phosphofructokinase; COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); Belongs to the carbohydrate kinase PfkB family.


ensembl_gene_id: PB1_12874
symbol: PB1_12874
gene_biotype: protein_coding
description:
  Monogalactosyldiacylglycerol synthase; COG0707 UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase.


ensembl_gene_id: PB1_13084
symbol: PB1_13084
gene_biotype: protein_coding
description:
  FAD dependent oxidoreductase; COG0578 Glycerol-3-phosphate dehydrogenase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.


ensembl_gene_id: PB1_13089
symbol: ku
gene_biotype: protein_coding
description:
  Hypothetical protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.


ensembl_gene_id: PB1_13099
symbol: dapF
gene_biotype: protein_coding
description:
  Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.


ensembl_gene_id: PB1_13109
symbol: ribH
gene_biotype: protein_coding
description:
  6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family.


ensembl_gene_id: PB1_13114
symbol: ribBA
gene_biotype: protein_coding
description:
  3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.


ensembl_gene_id: PB1_13124
symbol: PB1_13124
gene_biotype: protein_coding
description:
  Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.


ensembl_gene_id: PB1_13179
symbol: PB1_13179
gene_biotype: protein_coding
description:
  3-ketoacyl-(acyl-carrier-protein) reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: PB1_13229
symbol: PB1_13229
gene_biotype: protein_coding
description:
  Two component transcriptional regulator, winged helix family protein; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: PB1_13364
symbol: PB1_13364
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: PB1_13399
symbol: msrB
gene_biotype: protein_coding
description:
  methionine-R-sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.


ensembl_gene_id: PB1_13419
symbol: PB1_13419
gene_biotype: protein_coding
description:
  Cu2+-binding oxygen sensor protein; COG1999 Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems.


ensembl_gene_id: PB1_13429
symbol: tatC
gene_biotype: protein_coding
description:
  Twin-arginine protein translocation pathway component TatAD; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes.


ensembl_gene_id: PB1_13434
symbol: tatA
gene_biotype: protein_coding
description:
  Twin arginine translocase protein A; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.


ensembl_gene_id: PB1_13439
symbol: ilvA
gene_biotype: protein_coding
description:
  Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.


ensembl_gene_id: PB1_13444
symbol: PB1_13444
gene_biotype: protein_coding
description:
  Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.


ensembl_gene_id: PB1_13449
symbol: thyA
gene_biotype: protein_coding
description:
  Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.


ensembl_gene_id: PB1_13489
symbol: PB1_13489
gene_biotype: protein_coding
description:
  ABC transporter, ATP-binding protein; COG0488 ATPase components of ABC transporters with duplicated ATPase domains.


ensembl_gene_id: PB1_13509
symbol: fhs
gene_biotype: protein_coding
description:
  Formate--tetrahydrofolate ligase; COG2759 Formyltetrahydrofolate synthetase; Belongs to the formate--tetrahydrofolate ligase family.


ensembl_gene_id: PB1_13514
symbol: metAA
gene_biotype: protein_coding
description:
  Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.


ensembl_gene_id: PB1_13519
symbol: PB1_13519
gene_biotype: protein_coding
description:
  Diacylglycerol glucosyltransferase; COG0707 UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase.


ensembl_gene_id: PB1_13529
symbol: mntR
gene_biotype: protein_coding
description:
  Manganese transport transcriptional regulator; Central regulator of manganese homeostasis. Belongs to the DtxR/MntR family.


ensembl_gene_id: PB1_13574
symbol: PB1_13574
gene_biotype: protein_coding
description:
  Manganese ABC transporter ATP-binding protein; COG1121 ABC-type Mn/Zn transport systems, ATPase component.


ensembl_gene_id: PB1_13579
symbol: PB1_13579
gene_biotype: protein_coding
description:
  Periplasmic solute binding protein; COG0803 ABC-type metal ion transport system, periplasmic component/surface adhesin; Belongs to the bacterial solute-binding protein 9 family.


ensembl_gene_id: PB1_13674
symbol: xpt
gene_biotype: protein_coding
description:
  Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.


ensembl_gene_id: PB1_13689
symbol: PB1_13689
gene_biotype: protein_coding
description:
  COG0843 Heme/copper-type cytochrome/quinol oxidases, subunit 1; Belongs to the heme-copper respiratory oxidase family.


ensembl_gene_id: PB1_13699
symbol: PB1_13699
gene_biotype: protein_coding
description:
  Thermostable carboxypeptidase 1; Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.


ensembl_gene_id: PB1_13739
symbol: PB1_13739
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1251 NAD(P)H-nitrite reductase; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.


ensembl_gene_id: PB1_13744
symbol: PB1_13744
gene_biotype: protein_coding
description:
  Assimilatory nitrate reductase catalytic subunit; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: PB1_13769
symbol: gpsB
gene_biotype: protein_coding
description:
  Cell division protein GpsB; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation.


ensembl_gene_id: PB1_13784
symbol: PB1_13784
gene_biotype: protein_coding
description:
  ATP-dependent RNA helicase yprA; COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster.


ensembl_gene_id: PB1_13794
symbol: PB1_13794
gene_biotype: protein_coding
description:
  Crp/Fnr family transcriptional regulator; COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases.


ensembl_gene_id: PB1_13804
symbol: PB1_13804
gene_biotype: protein_coding
description:
  COG0071 Molecular chaperone (small heat shock protein); Belongs to the small heat shock protein (HSP20) family.


ensembl_gene_id: PB1_13834
symbol: recU
gene_biotype: protein_coding
description:
  Holliday junction-specific endonuclease; Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation; Belongs to the RecU family.


ensembl_gene_id: PB1_13849
symbol: nth
gene_biotype: protein_coding
description:
  Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.


ensembl_gene_id: PB1_13869
symbol: PB1_13869
gene_biotype: protein_coding
description:
  Peptidase propeptide and ypeb domain protein; COG5353 Uncharacterized protein conserved in bacteria.


ensembl_gene_id: PB1_13884
symbol: panD
gene_biotype: protein_coding
description:
  Aspartate alpha-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.


ensembl_gene_id: PB1_13889
symbol: panC
gene_biotype: protein_coding
description:
  Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.


ensembl_gene_id: PB1_13894
symbol: panB
gene_biotype: protein_coding
description:
  3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.


ensembl_gene_id: PB1_13899
symbol: birA
gene_biotype: protein_coding
description:
  Bifunctional BirA, biotin operon repressor/biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.


ensembl_gene_id: PB1_13904
symbol: cca
gene_biotype: protein_coding
description:
  tRNA CCA-pyrophosphorylase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.


ensembl_gene_id: PB1_13924
symbol: dapB
gene_biotype: protein_coding
description:
  Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.


ensembl_gene_id: PB1_13954
symbol: PB1_13954
gene_biotype: protein_coding
description:
  Menaquinol-cytochrome c reductase cytochrome b/c subunit; Component of the menaquinol-cytochrome c reductase complex.


ensembl_gene_id: PB1_13989
symbol: aroA
gene_biotype: protein_coding
description:
  3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.


ensembl_gene_id: PB1_13999
symbol: hisC
gene_biotype: protein_coding
description:
  COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.


ensembl_gene_id: PB1_14004
symbol: PB1_14004
gene_biotype: protein_coding
description:
  Chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis.


ensembl_gene_id: PB1_14009
symbol: aroB
gene_biotype: protein_coding
description:
  3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).


ensembl_gene_id: PB1_14014
symbol: aroC
gene_biotype: protein_coding
description:
  Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.


ensembl_gene_id: PB1_14024
symbol: ndk
gene_biotype: protein_coding
description:
  Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.


ensembl_gene_id: PB1_14029
symbol: hepT
gene_biotype: protein_coding
description:
  Heptaprenyl diphosphate synthase component II; COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.


ensembl_gene_id: PB1_14039
symbol: ubiE
gene_biotype: protein_coding
description:
  Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).


ensembl_gene_id: PB1_14049
symbol: mtrB
gene_biotype: protein_coding
description:
  Transcription attenuation protein MtrB; Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan. Belongs to the MtrB family.


ensembl_gene_id: PB1_14059
symbol: PB1_14059
gene_biotype: protein_coding
description:
  DNA-binding protein HU; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.


ensembl_gene_id: PB1_14064
symbol: PB1_14064
gene_biotype: protein_coding
description:
  Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.


ensembl_gene_id: PB1_14079
symbol: gpsA
gene_biotype: protein_coding
description:
  COG0240 Glycerol-3-phosphate dehydrogenase; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.


ensembl_gene_id: PB1_14084
symbol: der
gene_biotype: protein_coding
description:
  GTP-binding protein Der; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.


ensembl_gene_id: PB1_14149
symbol: PB1_14149
gene_biotype: protein_coding
description:
  Hypothetical protein; Involved in the degradation of specific anti-sigma factors. Belongs to the protease PrsW family.


ensembl_gene_id: PB1_14164
symbol: yweB
gene_biotype: protein_coding
description:
  COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.


ensembl_gene_id: PB1_14184
symbol: PB1_14184
gene_biotype: protein_coding
description:
  LysM repeat protein; COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains).


ensembl_gene_id: PB1_14209
symbol: PB1_14209
gene_biotype: protein_coding
description:
  Hypothetical protein; Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins; Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.


ensembl_gene_id: PB1_14214
symbol: PB1_14214
gene_biotype: protein_coding
description:
  COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: PB1_14219
symbol: PB1_14219
gene_biotype: protein_coding
description:
  COG1387 Histidinol phosphatase and related hydrolases of the PHP family; Belongs to the PHP hydrolase family. HisK subfamily.


ensembl_gene_id: PB1_14264
symbol: PB1_14264
gene_biotype: protein_coding
description:
  Pseudouridine synthase; COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; Belongs to the pseudouridine synthase RsuA family.


ensembl_gene_id: PB1_14274
symbol: PB1_14274
gene_biotype: protein_coding
description:
  Spore maturation protein; COG2715 Uncharacterized membrane protein, required for spore maturation in B.subtilis.


ensembl_gene_id: PB1_14294
symbol: scpB
gene_biotype: protein_coding
description:
  Chromosome segregation and condensation protein, ScpB; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.


ensembl_gene_id: PB1_14299
symbol: scpA
gene_biotype: protein_coding
description:
  Segregation and condensation protein A; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.


ensembl_gene_id: PB1_14319
symbol: lysA
gene_biotype: protein_coding
description:
  Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.


ensembl_gene_id: PB1_14339
symbol: PB1_14339
gene_biotype: protein_coding
description:
  Sporulation sigma factor SigF; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.


ensembl_gene_id: PB1_14344
symbol: spoIIAB
gene_biotype: protein_coding
description:
  Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.


ensembl_gene_id: PB1_14349
symbol: PB1_14349
gene_biotype: protein_coding
description:
  COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Belongs to the anti-sigma-factor antagonist family.


ensembl_gene_id: PB1_14364
symbol: deoB
gene_biotype: protein_coding
description:
  Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family.


ensembl_gene_id: PB1_14369
symbol: xerD
gene_biotype: protein_coding
description:
  Site-specific tyrosine recombinase XerD; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.


ensembl_gene_id: PB1_14384
symbol: PB1_14384
gene_biotype: protein_coding
description:
  Stage II sporulation protein M; Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane.


ensembl_gene_id: PB1_14394
symbol: act
gene_biotype: protein_coding
description:
  Methanol dehydrogenase activator protein; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes.


ensembl_gene_id: PB1_14409
symbol: hmp
gene_biotype: protein_coding
description:
  Nitric oxide dioxygenase; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress; Belongs to the globin family. Two-domain flavohemoproteins subfamily.


ensembl_gene_id: PB1_14489
symbol: PB1_14489
gene_biotype: protein_coding
description:
  UV-damage repair protein UvrX; COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair; Belongs to the DNA polymerase type-Y family.


ensembl_gene_id: PB1_14499
symbol: PB1_14499
gene_biotype: protein_coding
description:
  Short-chain dehydrogenase/reductase SDR; COG0300 Short-chain dehydrogenases of various substrate specificities; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: PB1_14509
symbol: proC
gene_biotype: protein_coding
description:
  Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.


ensembl_gene_id: PB1_14514
symbol: namA
gene_biotype: protein_coding
description:
  NADPH dehydrogenase NamA; Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes; Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily.


ensembl_gene_id: PB1_14519
symbol: rnz
gene_biotype: protein_coding
description:
  Ribonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family.


ensembl_gene_id: PB1_14534
symbol: gnd
gene_biotype: protein_coding
description:
  6-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.


ensembl_gene_id: PB1_14539
symbol: dinB
gene_biotype: protein_coding
description:
  DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.


ensembl_gene_id: PB1_14579
symbol: PB1_14579
gene_biotype: protein_coding
description:
  Membrane ATPase/protein kinase; COG1703 Putative periplasmic protein kinase ArgK and related GTPases of G3E family.


ensembl_gene_id: PB1_14594
symbol: bkdB
gene_biotype: protein_coding
description:
  Branched-chain alpha-keto acid dehydrogenase subunit E2; COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes.


ensembl_gene_id: PB1_14599
symbol: bkdAB
gene_biotype: protein_coding
description:
  Branched-chain alpha-keto acid dehydrogenase, E1 subunit; COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit.


ensembl_gene_id: PB1_14604
symbol: bkdAA
gene_biotype: protein_coding
description:
  3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring); COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit.


ensembl_gene_id: PB1_14609
symbol: bfmbC
gene_biotype: protein_coding
description:
  COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes.


ensembl_gene_id: PB1_14644
symbol: spoOA
gene_biotype: protein_coding
description:
  Response regulator receiver protein; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.


ensembl_gene_id: PB1_14669
symbol: dxs
gene_biotype: protein_coding
description:
  1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.


ensembl_gene_id: PB1_14674
symbol: ispA
gene_biotype: protein_coding
description:
  Farnesyl diphosphate synthase; COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.


ensembl_gene_id: PB1_14679
symbol: xseB
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.


ensembl_gene_id: PB1_14684
symbol: xseA
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family.


ensembl_gene_id: PB1_14689
symbol: folD
gene_biotype: protein_coding
description:
  Methylenetetrahydrofolate dehydrogenase (NADP(+))/ methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.


ensembl_gene_id: PB1_14694
symbol: nusB
gene_biotype: protein_coding
description:
  Transcription antitermination protein NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.


ensembl_gene_id: PB1_14704
symbol: PB1_14704
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.


ensembl_gene_id: PB1_14709
symbol: PB1_14709
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.


ensembl_gene_id: PB1_14759
symbol: efp
gene_biotype: protein_coding
description:
  Elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.


ensembl_gene_id: PB1_14769
symbol: aroQ
gene_biotype: protein_coding
description:
  3-dehydroquinate dehydratase II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.


ensembl_gene_id: PB1_14789
symbol: PB1_14789
gene_biotype: protein_coding
description:
  Phospholipase, patatin family protein; COG1752 Predicted esterase of the alpha-beta hydrolase superfamily.


ensembl_gene_id: PB1_14794
symbol: PB1_14794
gene_biotype: protein_coding
description:
  Ribonucleotide-diphosphate reductase subunit alpha; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.


ensembl_gene_id: PB1_14799
symbol: lipM
gene_biotype: protein_coding
description:
  Lipoate-protein ligase A; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation.


ensembl_gene_id: PB1_14809
symbol: gcvPB
gene_biotype: protein_coding
description:
  Glycine dehydrogenase subunit 2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily.


ensembl_gene_id: PB1_14814
symbol: gcvPA
gene_biotype: protein_coding
description:
  Glycine dehydrogenase subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.


ensembl_gene_id: PB1_14819
symbol: gcvT
gene_biotype: protein_coding
description:
  Glycine cleavage system aminomethyltransferase T; The glycine cleavage system catalyzes the degradation of glycine.


ensembl_gene_id: PB1_14839
symbol: aroK
gene_biotype: protein_coding
description:
  Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.


ensembl_gene_id: PB1_14874
symbol: PB1_14874
gene_biotype: protein_coding
description:
  Competence protein comGA; COG2804 Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB.


ensembl_gene_id: PB1_14909
symbol: PB1_14909
gene_biotype: protein_coding
description:
  gamma-D-glutamyl-L-diamino acid endopeptidase I; COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains).


ensembl_gene_id: PB1_14914
symbol: PB1_14914
gene_biotype: protein_coding
description:
  COG1368 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily; Belongs to the LTA synthase family.


ensembl_gene_id: PB1_14934
symbol: PB1_14934
gene_biotype: protein_coding
description:
  Serine protease of Rhomboid family; Contains TPR repeats; COG0705 Uncharacterized membrane protein (homolog of Drosophila rhomboid).


ensembl_gene_id: PB1_14944
symbol: PB1_14944
gene_biotype: protein_coding
description:
  COG0212 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.


ensembl_gene_id: PB1_14979
symbol: PB1_14979
gene_biotype: protein_coding
description:
  Phosphate transport system regulatory protein PhoU; Plays a role in the regulation of phosphate uptake.


ensembl_gene_id: PB1_14984
symbol: pstB
gene_biotype: protein_coding
description:
  Phosphate ABC transporter ATPase; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.


ensembl_gene_id: PB1_14994
symbol: PB1_14994
gene_biotype: protein_coding
description:
  Phosphate ABC transporter permease; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: PB1_15014
symbol: ppk
gene_biotype: protein_coding
description:
  Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family.


ensembl_gene_id: PB1_15024
symbol: PB1_15024
gene_biotype: protein_coding
description:
  Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.


ensembl_gene_id: PB1_15054
symbol: ispG
gene_biotype: protein_coding
description:
  4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family.


ensembl_gene_id: PB1_15069
symbol: zur
gene_biotype: protein_coding
description:
  Fur family transcriptional regulator protein; COG0735 Fe2+/Zn2+ uptake regulation proteins; Belongs to the Fur family.


ensembl_gene_id: PB1_15074
symbol: PB1_15074
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG1108 ABC-type Mn2+/Zn2+ transport systems, permease components.


ensembl_gene_id: PB1_15079
symbol: PB1_15079
gene_biotype: protein_coding
description:
  Cation ABC transporter ATP-binding protein; COG1121 ABC-type Mn/Zn transport systems, ATPase component.


ensembl_gene_id: PB1_15094
symbol: nfo
gene_biotype: protein_coding
description:
  Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.


ensembl_gene_id: PB1_15099
symbol: cshB
gene_biotype: protein_coding
description:
  DEAD/DEAH box helicase domain protein; Probable DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures.


ensembl_gene_id: PB1_15109
symbol: ispH
gene_biotype: protein_coding
description:
  4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.


ensembl_gene_id: PB1_15139
symbol: sigA
gene_biotype: protein_coding
description:
  RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.


ensembl_gene_id: PB1_15144
symbol: dnaG
gene_biotype: protein_coding
description:
  DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.


ensembl_gene_id: PB1_15154
symbol: mprF
gene_biotype: protein_coding
description:
  Putative lysylphosphatidylglycerol synthetase MprF; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.


ensembl_gene_id: PB1_15159
symbol: PB1_15159
gene_biotype: protein_coding
description:
  PEP synthetase regulatory protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.


ensembl_gene_id: PB1_15169
symbol: glyQS
gene_biotype: protein_coding
description:
  glycyl-tRNA synthetase; Catalyzes the attachment of glycine to tRNA(Gly). Belongs to the class-II aminoacyl-tRNA synthetase family.


ensembl_gene_id: PB1_15184
symbol: era
gene_biotype: protein_coding
description:
  GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.


ensembl_gene_id: PB1_15189
symbol: PB1_15189
gene_biotype: protein_coding
description:
  Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.


ensembl_gene_id: PB1_15199
symbol: ybeY
gene_biotype: protein_coding
description:
  Putative metal-dependent hydrolase; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.


ensembl_gene_id: PB1_15259
symbol: PB1_15259
gene_biotype: protein_coding
description:
  16S ribosomal RNA methyltransferase RsmE; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.


ensembl_gene_id: PB1_15264
symbol: prmA
gene_biotype: protein_coding
description:
  Ribosomal protein L11 methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family.


ensembl_gene_id: PB1_15269
symbol: dnaJ
gene_biotype: protein_coding
description:
  Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]


ensembl_gene_id: PB1_15279
symbol: grpE
gene_biotype: protein_coding
description:
  GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]


ensembl_gene_id: PB1_15284
symbol: hrcA
gene_biotype: protein_coding
description:
  Heat-inducible transcription repressor; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons.


ensembl_gene_id: PB1_15289
symbol: PB1_15289
gene_biotype: protein_coding
description:
  Coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.


ensembl_gene_id: PB1_15294
symbol: lepA
gene_biotype: protein_coding
description:
  GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.


ensembl_gene_id: PB1_15314
symbol: gpr
gene_biotype: protein_coding
description:
  Germination protease; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family.


ensembl_gene_id: PB1_15344
symbol: PB1_15344
gene_biotype: protein_coding
description:
  DNA internalization-related competence protein ComEC/Rec2; COG0658 Predicted membrane metal-binding protein.


ensembl_gene_id: PB1_15359
symbol: proC-2
gene_biotype: protein_coding
description:
  Late competence protein ComER; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.


ensembl_gene_id: PB1_15369
symbol: rsfS
gene_biotype: protein_coding
description:
  Hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.


ensembl_gene_id: PB1_15379
symbol: nadD
gene_biotype: protein_coding
description:
  Nicotinic acid mononucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).


ensembl_gene_id: PB1_15389
symbol: aroE
gene_biotype: protein_coding
description:
  Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).


ensembl_gene_id: PB1_15409
symbol: psd
gene_biotype: protein_coding
description:
  Phosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).


ensembl_gene_id: PB1_15414
symbol: PB1_15414
gene_biotype: protein_coding
description:
  COG1183 Phosphatidylserine synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: PB1_15419
symbol: PB1_15419
gene_biotype: protein_coding
description:
  Sporulation sigma factor SigK; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.


ensembl_gene_id: PB1_15434
symbol: PB1_15434
gene_biotype: protein_coding
description:
  O-acetylserine lyase; COG0031 Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.


ensembl_gene_id: PB1_15439
symbol: mtnN
gene_biotype: protein_coding
description:
  5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.


ensembl_gene_id: PB1_15464
symbol: greA
gene_biotype: protein_coding
description:
  Transcription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.


ensembl_gene_id: PB1_15489
symbol: mltG
gene_biotype: protein_coding
description:
  Aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family.


ensembl_gene_id: PB1_15499
symbol: PB1_15499
gene_biotype: protein_coding
description:
  Holliday junction resolvase-like protein; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family.


ensembl_gene_id: PB1_15509
symbol: alaS
gene_biotype: protein_coding
description:
  alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.


ensembl_gene_id: PB1_15539
symbol: recD2
gene_biotype: protein_coding
description:
  Helicase, RecD/TraA family protein; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily.


ensembl_gene_id: PB1_15569
symbol: PB1_15569
gene_biotype: protein_coding
description:
  Hypothetical protein; COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase.


ensembl_gene_id: PB1_15579
symbol: aspS
gene_biotype: protein_coding
description:
  aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.


ensembl_gene_id: PB1_15599
symbol: dtd
gene_biotype: protein_coding
description:
  D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family.


ensembl_gene_id: PB1_15604
symbol: PB1_15604
gene_biotype: protein_coding
description:
  GTP pyrophosphokinase RelA/SpoT; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.


ensembl_gene_id: PB1_15609
symbol: apt
gene_biotype: protein_coding
description:
  Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.


ensembl_gene_id: PB1_15619
symbol: PB1_15619
gene_biotype: protein_coding
description:
  COG0053 Predicted Co/Zn/Cd cation transporters; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.


ensembl_gene_id: PB1_15624
symbol: secF
gene_biotype: protein_coding
description:
  Bifunctional preprotein translocase subunit SecD/SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily.


ensembl_gene_id: PB1_15664
symbol: tgt
gene_biotype: protein_coding
description:
  Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...]


ensembl_gene_id: PB1_15669
symbol: queA
gene_biotype: protein_coding
description:
  S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).


ensembl_gene_id: PB1_15679
symbol: ruvB
gene_biotype: protein_coding
description:
  Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.


ensembl_gene_id: PB1_15689
symbol: ruvA
gene_biotype: protein_coding
description:
  Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.


ensembl_gene_id: PB1_15719
symbol: nadA
gene_biotype: protein_coding
description:
  Quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.


ensembl_gene_id: PB1_15749
symbol: obgE
gene_biotype: protein_coding
description:
  GTPase CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.


ensembl_gene_id: PB1_15769
symbol: rplU
gene_biotype: protein_coding
description:
  50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.


ensembl_gene_id: PB1_15794
symbol: minC
gene_biotype: protein_coding
description:
  Septum formation inhibitor; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family.


ensembl_gene_id: PB1_15819
symbol: PB1_15819
gene_biotype: protein_coding
description:
  Maf-like protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.


ensembl_gene_id: PB1_15844
symbol: PB1_15844
gene_biotype: protein_coding
description:
  Prepilin peptidase; COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases.


ensembl_gene_id: PB1_15904
symbol: PB1_15904
gene_biotype: protein_coding
description:
  Folyl-polyglutamate synthetase; COG0285 Folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family.


ensembl_gene_id: PB1_15909
symbol: valS
gene_biotype: protein_coding
description:
  valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.


ensembl_gene_id: PB1_15934
symbol: PB1_15934
gene_biotype: protein_coding
description:
  Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.


ensembl_gene_id: PB1_15939
symbol: hemC
gene_biotype: protein_coding
description:
  Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.


ensembl_gene_id: PB1_15944
symbol: PB1_15944
gene_biotype: protein_coding
description:
  uroporphyrin-III C-methyltransferase; COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component.


ensembl_gene_id: PB1_15949
symbol: hemA
gene_biotype: protein_coding
description:
  glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).


ensembl_gene_id: PB1_15959
symbol: engB
gene_biotype: protein_coding
description:
  GTP-binding protein YsxC; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.


ensembl_gene_id: PB1_15964
symbol: lon
gene_biotype: protein_coding
description:
  ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.


ensembl_gene_id: PB1_15974
symbol: clpX
gene_biotype: protein_coding
description:
  ATP-dependent protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.


ensembl_gene_id: PB1_15979
symbol: tig
gene_biotype: protein_coding
description:
  Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.


ensembl_gene_id: PB1_15989
symbol: leuD
gene_biotype: protein_coding
description:
  Isopropylmalate isomerase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.


ensembl_gene_id: PB1_15994
symbol: leuC
gene_biotype: protein_coding
description:
  Isopropylmalate isomerase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.


ensembl_gene_id: PB1_15999
symbol: leuB
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.


ensembl_gene_id: PB1_16004
symbol: leuA
gene_biotype: protein_coding
description:
  2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.


ensembl_gene_id: PB1_16009
symbol: ilvC
gene_biotype: protein_coding
description:
  Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.


ensembl_gene_id: PB1_16019
symbol: PB1_16019
gene_biotype: protein_coding
description:
  COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase].


ensembl_gene_id: PB1_16024
symbol: ilvE
gene_biotype: protein_coding
description:
  Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: PB1_16039
symbol: PB1_16039
gene_biotype: protein_coding
description:
  Nucleoside-triphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.


ensembl_gene_id: PB1_16044
symbol: rph
gene_biotype: protein_coding
description:
  Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.


ensembl_gene_id: PB1_16114
symbol: PB1_16114
gene_biotype: protein_coding
description:
  Transcriptional regulator xre family, bacteriophage lambda repressor c1 like protein; COG1396 Predicted transcriptional regulators.


ensembl_gene_id: PB1_16374
symbol: PB1_16374
gene_biotype: protein_coding
description:
  RNA polymerase sigma factor for flagellar operon; COG1191 DNA-directed RNA polymerase specialized sigma subunit; Belongs to the sigma-70 factor family.


ensembl_gene_id: PB1_16549
symbol: uvrC
gene_biotype: protein_coding
description:
  Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.


ensembl_gene_id: PB1_16579
symbol: PB1_16579
gene_biotype: protein_coding
description:
  Type I phosphodiesterase/nucleotide pyrophosphatase; COG1524 Uncharacterized proteins of the AP superfamily.


ensembl_gene_id: PB1_16584
symbol: mprF-2
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.


ensembl_gene_id: PB1_16614
symbol: PB1_16614
gene_biotype: protein_coding
description:
  COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: PB1_16634
symbol: mutS2
gene_biotype: protein_coding
description:
  Recombination and DNA strand exchange inhibitor protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.


ensembl_gene_id: PB1_16644
symbol: PB1_16644
gene_biotype: protein_coding
description:
  Colicin V production protein; COG1286 Uncharacterized membrane protein, required for colicin V production.


ensembl_gene_id: PB1_16649
symbol: zapA
gene_biotype: protein_coding
description:
  Cell division protein ZapA; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.


ensembl_gene_id: PB1_16659
symbol: pheT
gene_biotype: protein_coding
description:
  phenylalanyl-tRNA synthetase subunit beta; COG0073 EMAP domain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.


ensembl_gene_id: PB1_16664
symbol: pheS
gene_biotype: protein_coding
description:
  COG0016 Phenylalanyl-tRNA synthetase alpha subunit; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.


ensembl_gene_id: PB1_16669
symbol: PB1_16669
gene_biotype: protein_coding
description:
  23S rRNA methyltransferase; COG0566 rRNA methylases; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.


ensembl_gene_id: PB1_16694
symbol: rplT
gene_biotype: protein_coding
description:
  50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.


ensembl_gene_id: PB1_16704
symbol: infC
gene_biotype: protein_coding
description:
  Translation initiation factor 3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.


ensembl_gene_id: PB1_16709
symbol: thrS
gene_biotype: protein_coding
description:
  threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).


ensembl_gene_id: PB1_16729
symbol: nrdR
gene_biotype: protein_coding
description:
  Transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.


ensembl_gene_id: PB1_16734
symbol: speH
gene_biotype: protein_coding
description:
  S-adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.


ensembl_gene_id: PB1_16744
symbol: coaE
gene_biotype: protein_coding
description:
  dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.


ensembl_gene_id: PB1_16754
symbol: mutM
gene_biotype: protein_coding
description:
  Formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.


ensembl_gene_id: PB1_16759
symbol: polA
gene_biotype: protein_coding
description:
  DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.


ensembl_gene_id: PB1_16784
symbol: citH
gene_biotype: protein_coding
description:
  Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.


ensembl_gene_id: PB1_16819
symbol: pfk2
gene_biotype: protein_coding
description:
  6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.


ensembl_gene_id: PB1_16824
symbol: accA
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.


ensembl_gene_id: PB1_16829
symbol: accD
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase, carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.


ensembl_gene_id: PB1_16919
symbol: PB1_16919
gene_biotype: protein_coding
description:
  COG2220 Predicted Zn-dependent hydrolases of the beta-lactamase fold; Belongs to the UPF0173 family.


ensembl_gene_id: PB1_16939
symbol: argG
gene_biotype: protein_coding
description:
  COG0137 Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.


ensembl_gene_id: PB1_16949
symbol: PB1_16949
gene_biotype: protein_coding
description:
  Molybdenum cofactor synthesis domain protein; May be involved in the biosynthesis of molybdopterin. Belongs to the MoaB/Mog family.


ensembl_gene_id: PB1_16959
symbol: ackA
gene_biotype: protein_coding
description:
  Acetate kinase A/propionate kinase 2; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.


ensembl_gene_id: PB1_16974
symbol: tpx
gene_biotype: protein_coding
description:
  Redoxin domain protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily.


ensembl_gene_id: PB1_17014
symbol: thiI
gene_biotype: protein_coding
description:
  Thiamine biosynthesis protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.


ensembl_gene_id: PB1_17024
symbol: ezrA
gene_biotype: protein_coding
description:
  Septation ring formation regulator EzrA; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family.


ensembl_gene_id: PB1_17029
symbol: PB1_17029
gene_biotype: protein_coding
description:
  Histidinol-phosphatase; COG1387 Histidinol phosphatase and related hydrolases of the PHP family; Belongs to the PHP hydrolase family. HisK subfamily.


ensembl_gene_id: PB1_17049
symbol: rpsD
gene_biotype: protein_coding
description:
  30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.


ensembl_gene_id: PB1_17059
symbol: tyrS
gene_biotype: protein_coding
description:
  Tyrosyl-tRNA synthetase, cluster 1; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.


ensembl_gene_id: PB1_17074
symbol: PB1_17074
gene_biotype: protein_coding
description:
  Acetoin utilization protein; Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue.


ensembl_gene_id: PB1_17109
symbol: PB1_17109
gene_biotype: protein_coding
description:
  COG4768 Uncharacterized protein containing a divergent version of the methyl-accepting chemotaxis-like domain.


ensembl_gene_id: PB1_17139
symbol: PB1_17139
gene_biotype: protein_coding
description:
  NTPase; Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.


ensembl_gene_id: PB1_17154
symbol: trmB
gene_biotype: protein_coding
description:
  tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.


ensembl_gene_id: PB1_17169
symbol: PB1_17169
gene_biotype: protein_coding
description:
  COG1523 Type II secretory pathway, pullulanase PulA and related glycosidases; Belongs to the glycosyl hydrolase 13 family.


ensembl_gene_id: PB1_17179
symbol: PB1_17179
gene_biotype: protein_coding
description:
  2'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family.


ensembl_gene_id: PB1_17189
symbol: PB1_17189
gene_biotype: protein_coding
description:
  Dipeptidase; COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases.


ensembl_gene_id: PB1_17234
symbol: PB1_17234
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: PB1_17254
symbol: PB1_17254
gene_biotype: protein_coding
description:
  Sam-dependent methyltransferase, mraw methylase family protein; COG0500 SAM-dependent methyltransferases.


ensembl_gene_id: PB1_17289
symbol: metK
gene_biotype: protein_coding
description:
  S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.


ensembl_gene_id: PB1_17299
symbol: pckA
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.


ensembl_gene_id: PB1_17324
symbol: PB1_17324
gene_biotype: protein_coding
description:
  Nucleoside triphosphate phosphohydrolase; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; Belongs to the Nudix hydrolase family.


ensembl_gene_id: PB1_17364
symbol: luxS
gene_biotype: protein_coding
description:
  S-ribosylhomocysteinase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.


ensembl_gene_id: PB1_17369
symbol: PB1_17369
gene_biotype: protein_coding
description:
  Hypothetical protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family.


ensembl_gene_id: PB1_17379
symbol: PB1_17379
gene_biotype: protein_coding
description:
  Zinc-binding protein adcA; COG0803 ABC-type metal ion transport system, periplasmic component/surface adhesin; Belongs to the bacterial solute-binding protein 9 family.


ensembl_gene_id: PB1_17389
symbol: menE
gene_biotype: protein_coding
description:
  O-succinylbenzoic acid--CoA ligase; Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA (OSB-CoA); Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily.


ensembl_gene_id: PB1_17394
symbol: menB
gene_biotype: protein_coding
description:
  Dihydroxynaphthoic acid synthetase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA).


ensembl_gene_id: PB1_17399
symbol: menH
gene_biotype: protein_coding
description:
  Alpha/beta hydrolase fold protein; Catalyzes a proton abstraction reaction that results in 2,5- elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6- hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).


ensembl_gene_id: PB1_17404
symbol: menD
gene_biotype: protein_coding
description:
  2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily.


ensembl_gene_id: PB1_17414
symbol: menA
gene_biotype: protein_coding
description:
  1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily.


ensembl_gene_id: PB1_17419
symbol: PB1_17419
gene_biotype: protein_coding
description:
  Glycogen phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.


ensembl_gene_id: PB1_17434
symbol: glgC
gene_biotype: protein_coding
description:
  Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.


ensembl_gene_id: PB1_17439
symbol: glgB
gene_biotype: protein_coding
description:
  Glycogen branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.


